| Year |
Citation |
Score |
| 2024 |
Gadgil RY, Rider SD, Shrestha R, Alhawach V, Hitch DC, Leffak M. Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs. Biorxiv : the Preprint Server For Biology. PMID 38260482 DOI: 10.1101/2024.01.12.575055 |
0.429 |
|
| 2023 |
Rider SD, Damewood FJ, Gadgil RY, Hitch DC, Alhawach V, Shrestha R, Shanahan M, Zavada N, Leffak M. Suppressors of Break-Induced Replication in Human Cells. Genes. 14. PMID 36833325 DOI: 10.3390/genes14020398 |
0.459 |
|
| 2022 |
Rider SD, Gadgil RY, Hitch DC, Damewood FJ, Zavada N, Shanahan M, Alhawach V, Shrestha R, Shin-Ya K, Leffak M. Stable G-quadruplex DNA structures promote replication-dependent genome instability. The Journal of Biological Chemistry. 101947. PMID 35447109 DOI: 10.1016/j.jbc.2022.101947 |
0.352 |
|
| 2020 |
Gadgil RY, Romer EJ, Goodman CC, Rider SD, Damewood FJ, Barthelemy JR, Shin-Ya K, Hanenberg H, Leffak M. Replication stress at microsatellites causes DNA double strand breaks and break induced replication. The Journal of Biological Chemistry. PMID 32873711 DOI: 10.1074/Jbc.Ra120.013495 |
0.539 |
|
| 2020 |
Gadgil RY, Rider SD, Lewis T, Barthelemy J, Leffak M. Analysis of Trinucleotide Repeat Stability by Integration at a Chromosomal Ectopic Site. Methods in Molecular Biology (Clifton, N.J.). 2056: 121-136. PMID 31586345 DOI: 10.1007/978-1-4939-9784-8_8 |
0.488 |
|
| 2019 |
Lewis TW, Barthelemy JR, Virts EL, Kennedy FM, Gadgil RY, Wiek C, Linka RM, Zhang F, Andreassen PR, Hanenberg H, Leffak M. Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination. Nucleic Acids Research. PMID 30715513 DOI: 10.1093/Nar/Gkz026 |
0.445 |
|
| 2018 |
Poudel S, Yao J, Kemp MG, Leffak M. Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells. The Journal of Biological Chemistry. PMID 30037903 DOI: 10.1074/Jbc.Ra118.004519 |
0.431 |
|
| 2017 |
Leffak M. Break-induced replication links microsatellite expansion to complex genome rearrangements. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28621832 DOI: 10.1002/Bies.201700025 |
0.482 |
|
| 2016 |
Leffak M, Gadgil R, Barthelemy J, Lewis T. Replication stalling and DNA microsatellite instability. Biophysical Chemistry. PMID 27914716 DOI: 10.1016/J.Bpc.2016.11.007 |
0.378 |
|
| 2016 |
Barthelemy J, Hanenberg H, Leffak M. FANCJ is essential to maintain microsatellite structure genome-wide during replication stress. Nucleic Acids Research. PMID 27794046 DOI: 10.1093/Nar/Gkw1091 |
0.489 |
|
| 2016 |
Guo J, Gu L, Leffak M, Li GM. MutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesis. Cell Research. PMID 27255792 DOI: 10.1038/Cr.2016.66 |
0.456 |
|
| 2016 |
Barthelemy J, Hanenberg H, Leffak M. FANCJ is essential to maintain microsatellite structure genome-wide during replication stress. Nucleic Acids Research. PMID 27179029 DOI: 10.1093/nar/gkw433 |
0.394 |
|
| 2015 |
Virts EL, Jankowska A, Mackay C, Glaas MF, Wiek C, Kelich SL, Lottmann N, Kennedy FM, Marchal C, Lehnert E, Scharf RE, Dufour C, Lanciotti M, Farruggia P, Santoro A, ... ... Leffak M, et al. AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia. Human Molecular Genetics. PMID 26085575 DOI: 10.1093/Hmg/Ddv227 |
0.389 |
|
| 2014 |
Gao Y, Yao J, Poudel S, Romer E, Abu-Niaaj L, Leffak M. Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation. The Journal of Biological Chemistry. 289: 35987-6000. PMID 25258324 DOI: 10.1074/Jbc.M114.589119 |
0.384 |
|
| 2013 |
Chen X, Liu G, Leffak M. Activation of a human chromosomal replication origin by protein tethering. Nucleic Acids Research. 41: 6460-74. PMID 23658226 DOI: 10.1093/Nar/Gkt368 |
0.466 |
|
| 2013 |
Leffak M. Hypothesis: local dNTP depletion as the cause of microsatellite repeat instability during replication (comment on DOI 10.1002/bies.201200128). Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 305. PMID 23494534 DOI: 10.1002/Bies.201300026 |
0.462 |
|
| 2013 |
Liu G, Chen X, Leffak M. Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability. Molecular and Cellular Biology. 33: 571-81. PMID 23166299 DOI: 10.1128/Mcb.01265-12 |
0.475 |
|
| 2012 |
Liu G, Myers S, Chen X, Bissler JJ, Sinden RR, Leffak M. Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract. The Journal of Biological Chemistry. 287: 33412-23. PMID 22872635 DOI: 10.1074/Jbc.M112.402503 |
0.558 |
|
| 2012 |
Wang Z, Kim E, Leffak M, Xu YJ. Treslin, DUE-B, and GEMC1 cannot complement Sld3 mutants in fission yeast. Fems Yeast Research. 12: 486-90. PMID 22380713 DOI: 10.1111/J.1567-1364.2012.00794.X |
0.373 |
|
| 2012 |
Liu G, Leffak M. Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis. Cell & Bioscience. 2: 7. PMID 22369689 DOI: 10.1186/2045-3701-2-7 |
0.39 |
|
| 2012 |
Liu G, Chen X, Gao Y, Lewis T, Barthelemy J, Leffak M. Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instability. Molecular and Cellular Biology. 32: 1618-32. PMID 22354993 DOI: 10.1128/Mcb.06727-11 |
0.38 |
|
| 2010 |
Liu G, Chen X, Bissler JJ, Sinden RR, Leffak M. Replication-dependent instability at (CTG) x (CAG) repeat hairpins in human cells. Nature Chemical Biology. 6: 652-9. PMID 20676085 DOI: 10.1038/Nchembio.416 |
0.522 |
|
| 2010 |
Xu YJ, Leffak M. ATRIP from TopBP1 to ATR--in vitro activation of a DNA damage checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 107: 13561-2. PMID 20660767 DOI: 10.1073/Pnas.1008909107 |
0.514 |
|
| 2010 |
Chowdhury A, Liu G, Kemp M, Chen X, Katrangi N, Myers S, Ghosh M, Yao J, Gao Y, Bubulya P, Leffak M. The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation. Molecular and Cellular Biology. 30: 1495-507. PMID 20065034 DOI: 10.1128/Mcb.00710-09 |
0.405 |
|
| 2007 |
Liu G, Bissler JJ, Sinden RR, Leffak M. Unstable spinocerebellar ataxia type 10 (ATTCT*(AGAAT) repeats are associated with aberrant replication at the ATX10 locus and replication origin-dependent expansion at an ectopic site in human cells. Molecular and Cellular Biology. 27: 7828-38. PMID 17846122 DOI: 10.1128/Mcb.01276-07 |
0.439 |
|
| 2007 |
Kemp M, Bae B, Yu JP, Ghosh M, Leffak M, Nair SK. Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B. The Journal of Biological Chemistry. 282: 10441-8. PMID 17264083 DOI: 10.1074/Jbc.M609632200 |
0.459 |
|
| 2007 |
Specht S, Organisciak DT, Darrow RM, Leffak M. Continuing Damage to Rat Retinal DNA During Darkness Following Light Exposure Photochemistry and Photobiology. 71: 559-566. DOI: 10.1562/0031-8655(2000)0710559CDTRRD2.0.CO2 |
0.306 |
|
| 2006 |
Ghosh M, Kemp M, Liu G, Ritzi M, Schepers A, Leffak M. Differential binding of replication proteins across the human c-myc replicator. Molecular and Cellular Biology. 26: 5270-83. PMID 16809765 DOI: 10.1128/Mcb.02137-05 |
0.479 |
|
| 2005 |
Moaddel R, Price GB, Juteau JM, Leffak M, Wainer IW. The synthesis and initial characterization of an immobilized DNA unwinding element binding (DUE-B) protein chromatographic stationary phase. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 820: 197-203. PMID 15899373 DOI: 10.1016/J.Jchromb.2005.03.030 |
0.399 |
|
| 2005 |
Casper JM, Kemp MG, Ghosh M, Randall GM, Vaillant A, Leffak M. The c-myc DNA-unwinding element-binding protein modulates the assembly of DNA replication complexes in vitro. The Journal of Biological Chemistry. 280: 13071-83. PMID 15653697 DOI: 10.1074/Jbc.M404754200 |
0.422 |
|
| 2005 |
Kemp MG, Ghosh M, Liu G, Leffak M. The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells. Nucleic Acids Research. 33: 325-36. PMID 15653633 DOI: 10.1093/Nar/Gki177 |
0.498 |
|
| 2005 |
Ghosh M, Liu G, Randall G, Bevington J, Leffak M. Transcription factor binding and induced transcription alter chromosomal c-myc replicator activity. Molecular and Cellular Biology. 24: 10193-207. PMID 15542830 DOI: 10.1128/Mcb.24.23.10193-10207.2004 |
0.434 |
|
| 2005 |
Kemp MG, Ghosh M, Liu G, Leffak M. Erratum: The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells (Nucleic Acids Research (2005) vol. 33 (325-336)) Nucleic Acids Research. 33. DOI: 10.1093/Nar/Gki229 |
0.416 |
|
| 2003 |
Potaman VN, Bissler JJ, Hashem VI, Oussatcheva EA, Lu L, Shlyakhtenko LS, Lyubchenko YL, Matsuura T, Ashizawa T, Leffak M, Benham CJ, Sinden RR. Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats. Journal of Molecular Biology. 326: 1095-111. PMID 12589756 DOI: 10.1016/S0022-2836(03)00037-8 |
0.46 |
|
| 2003 |
Liu G, Malott M, Leffak M. Multiple functional elements comprise a Mammalian chromosomal replicator. Molecular and Cellular Biology. 23: 1832-42. PMID 12589000 DOI: 10.1128/Mcb.23.5.1832-1842.2003 |
0.546 |
|
| 2001 |
Dhar SK, Yoshida K, Machida Y, Khaira P, Chaudhuri B, Wohlschlegel JA, Leffak M, Yates J, Dutta A. Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. Cell. 106: 287-96. PMID 11509178 DOI: 10.1016/S0092-8674(01)00458-5 |
0.662 |
|
| 2001 |
Kamath S, Leffak M. Multiple sites of replication initiation in the human beta-globin gene locus. Nucleic Acids Research. 29: 809-17. PMID 11160905 DOI: 10.1093/Nar/29.3.809 |
0.5 |
|
| 2000 |
Tao L, Dong Z, Leffak M, Zannis-Hadjopoulos M, Price G. Major DNA replication initiation sites in the c-myc locus in human cells Journal of Cellular Biochemistry. 78: 442-457. PMID 10861842 DOI: 10.1002/1097-4644(20000901)78:3<442::Aid-Jcb9>3.0.Co;2-1 |
0.481 |
|
| 2000 |
Specht S, Organisciak DT, Darrow RM, Leffak M. Continuing damage to rat retinal DNA during darkness following light exposure. Photochemistry and Photobiology. 71: 559-66. PMID 10818786 DOI: 10.1562/0031-8655(2000)071<0559:Cdtrrd>2.0.Co;2 |
0.727 |
|
| 1999 |
Rein T, Kobayashi T, Malott M, Leffak M, DePamphilis ML. DNA methylation at mammalian replication origins. The Journal of Biological Chemistry. 274: 25792-800. PMID 10464318 DOI: 10.1074/Jbc.274.36.25792 |
0.336 |
|
| 1999 |
Malott M, Leffak M. Activity of the c-myc replicator at an ectopic chromosomal location. Molecular and Cellular Biology. 19: 5685-95. PMID 10409757 DOI: 10.1128/Mcb.19.8.5685 |
0.549 |
|
| 1999 |
Jones DR, Leffak M. A bifunctional regulatory element of the human ApoA-I gene responsive to a distal enhancer. Dna and Cell Biology. 18: 107-19. PMID 10073570 DOI: 10.1089/104454999315493 |
0.342 |
|
| 1999 |
Specht S, Leffak M, Darrow RM, Organisciak DT. Damage to Rat Retinal DNA Induced In Vivo by Visible Light Photochemistry and Photobiology. 69: 91-98. DOI: 10.1111/J.1751-1097.1999.Tb05311.X |
0.726 |
|
| 1998 |
Khaira P, James CD, Leffak M. Amplification of the translocated c-myc genes in three Burkitt lymphoma cell lines. Gene. 211: 101-8. PMID 9643977 DOI: 10.1016/S0378-1119(98)00104-8 |
0.663 |
|
| 1996 |
Waltz SE, Trivedi AA, Leffak M. DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cells Nucleic Acids Research. 24: 1887-1894. PMID 8657570 DOI: 10.1093/Nar/24.10.1887 |
0.696 |
|
| 1995 |
Berberich S, Trivedi A, Daniel DC, Johnson EM, Leffak M. In vitro replication of plasmids containing human c-myc DNA. Journal of Molecular Biology. 245: 92-109. PMID 7799437 DOI: 10.1006/Jmbi.1994.0010 |
0.568 |
|
| 1995 |
McWhinney C, Waltz SE, Leffak M. Cis-acting effects of sequences within 2.4-kb upstream of the human c-myc gene on autonomous plasmid replication in HeLa cells Dna and Cell Biology. 14: 565-579. PMID 7626216 DOI: 10.1089/Dna.1995.14.565 |
0.718 |
|
| 1993 |
Berberich S, Leffak M. DNase-sensitive chromatin structure near a chromosomal origin of bidirectional replication of the avian alpha-globin locus. Dna and Cell Biology. 12: 703-14. PMID 8397828 DOI: 10.1089/Dna.1993.12.703 |
0.382 |
|
| 1991 |
Kumar S, Leffak M. Conserved chromatin structure in c-myc 5'flanking DNA after viral transduction. Journal of Molecular Biology. 222: 45-57. PMID 1942068 DOI: 10.1016/0022-2836(91)90736-P |
0.495 |
|
| 1990 |
McWhinney C, Leffak M. Autonomous replication of a DNA fragment containing the chromosomal replication origin of the human c-myc gene. Nucleic Acids Research. 18: 1233-42. PMID 2157194 DOI: 10.1093/Nar/18.5.1233 |
0.575 |
|
| 1989 |
Kumar S, Leffak M. DNA topology of the ordered chromatin domain 5' to the human c-myc gene. Nucleic Acids Research. 17: 2819-33. PMID 2717410 DOI: 10.1093/NAR/17.7.2819 |
0.416 |
|
| 1989 |
Leffak M, James CD. Opposite replication polarity of the germ line c-myc gene in HeLa cells compared with that of two Burkitt lymphoma cell lines Molecular and Cellular Biology. 9: 586-593. PMID 2710118 DOI: 10.1128/Mcb.9.2.586 |
0.528 |
|
| 1988 |
Trempe JP, Lindstrom YI, Leffak M. Opposite replication polarities of transcribed and nontranscribed histone H5 genes Molecular and Cellular Biology. 8: 1657-1663. PMID 3380091 DOI: 10.1128/Mcb.8.4.1657 |
0.459 |
|
| 1988 |
Leffak M. Nonrandom assembly of chromatin during hydroxyurea inhibition of DNA synthesis. Biochemistry. 27: 686-91. PMID 3349057 DOI: 10.1021/Bi00402A029 |
0.312 |
|
| 1987 |
Fink PS, Whitford T, Leffak M, Prochaska LJ. Homology between bacterial DNA and bovine mitochondrial DNA encoding cytochrome c oxidase subunit III. Febs Letters. 214: 75-80. PMID 3032681 DOI: 10.1016/0014-5793(87)80016-9 |
0.499 |
|
| 1986 |
James CD, Leffak M. Polarity of DNA replication through the avian alpha-globin locus Molecular and Cellular Biology. 6: 976-984. PMID 3785167 DOI: 10.1128/Mcb.6.4.976 |
0.515 |
|
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