Year |
Citation |
Score |
2016 |
Almaliti J, Al-Hamashi AA, Negmeldin AT, Hanigan CL, Perera L, Pflum MK, Casero RA, Tillekeratne LM. Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue. Journal of Medicinal Chemistry. PMID 27809521 DOI: 10.1021/Acs.Jmedchem.6B01271 |
0.533 |
|
2014 |
Bhansali P, Hanigan CL, Perera L, Casero RA, Tillekeratne LM. Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups. European Journal of Medicinal Chemistry. 86: 528-41. PMID 25203782 DOI: 10.1016/J.Ejmech.2014.09.009 |
0.574 |
|
2013 |
Murray-Stewart T, Hanigan CL, Woster PM, Marton LJ, Casero RA. Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism Molecular Cancer Therapeutics. 12: 2088-2099. PMID 23943804 DOI: 10.1158/1535-7163.Mct-13-0418 |
0.532 |
|
2013 |
Jin L, Hanigan CL, Wu Y, Wang W, Park BH, Woster PM, Casero RA. Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1 (DNA methyltransferase 1)-independent manner Biochemical Journal. 449: 459-468. PMID 23072722 DOI: 10.1042/Bj20121360 |
0.526 |
|
2012 |
Yun J, Johnson JL, Hanigan CL, Locasale JW. Interactions between epigenetics and metabolism in cancers. Frontiers in Oncology. 2: 163. PMID 23162793 DOI: 10.3389/Fonc.2012.00163 |
0.428 |
|
2011 |
Bhansali P, Hanigan CL, Casero RA, Tillekeratne LM. Largazole and analogues with modified metal-binding motifs targeting histone deacetylases: synthesis and biological evaluation. Journal of Medicinal Chemistry. 54: 7453-63. PMID 21936551 DOI: 10.1021/Jm200432A |
0.562 |
|
2008 |
Hanigan CL, Van Engeland M, De Bruine AP, Wouters KA, Weijenberg MP, Eshleman JR, Herman JG. An inactivating mutation in HDAC2 leads to dysregulation of apoptosis mediated by APAF1. Gastroenterology. 135: 1654-1664.e2. PMID 18834886 DOI: 10.1053/J.Gastro.2008.07.078 |
0.408 |
|
2002 |
Futscher BW, Oshiro MM, Wozniak RJ, Holtan N, Hanigan CL, Duan H, Domann FE. Role for DNA methylation in the control of cell type specific maspin expression. Nature Genetics. 31: 175-9. PMID 12021783 DOI: 10.1038/Ng886 |
0.37 |
|
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