Bruno Gasnier, Ph. D. - Publications

Affiliations: 
CNRS UMR 8192 University Paris Descartes, Paris, Île-de-France, France 
Area:
Vesicular transporter

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jungnickel KEJ, Guelle O, Iguchi M, Dong W, Kotov V, Gabriel F, Debacker C, Dairou J, McCort-Tranchepain I, Laqtom NN, Chan SH, Ejima A, Sato K, Massa López D, Saftig P, ... ... Gasnier B, et al. MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nature Cell Biology. PMID 38839979 DOI: 10.1038/s41556-024-01436-5  0.346
2021 Leray X, Conti R, Li Y, Debacker C, Castelli F, Fenaille F, Zdebik AA, Pusch M, Gasnier B. Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34344826 DOI: 10.1073/pnas.2025315118  0.49
2021 Gasnier B. Plug-and-socket mechanisms in nutrient sensing by lysosomal amino acid transporters. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723009 DOI: 10.1073/pnas.2102173118  0.369
2020 Moriyama Y, Gasnier B. Transporters in acidic organelles. Biochimica Et Biophysica Acta. Biomembranes. 183458. PMID 32861642 DOI: 10.1016/j.bbamem.2020.183458  0.404
2018 Houdou M, Lebredonchel E, Garat A, Duvet S, Legrand D, Decool V, Klein A, Ouzzine M, Gasnier B, Potelle S, Foulquier F. Involvement of thapsigargin and cyclopiazonic acid-sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800387R. PMID 30307768 DOI: 10.1096/Fj.201800387R  0.401
2017 Fettelschoss V, Burda P, Sagné C, Coelho D, De Laet C, Lutz S, Suormala T, Fowler B, Pietrancosta N, Gasnier B, Bornhauser B, Froese DS, Baumgartner MR. Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1. The Journal of Biological Chemistry. PMID 28572511 DOI: 10.1074/Jbc.M117.784819  0.323
2017 Verdon Q, Boonen M, Ribes C, Jadot M, Gasnier B, Sagné C. SNAT7 is the primary lysosomal glutamine exporter required for extracellular protein-dependent growth of cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416685 DOI: 10.1073/Pnas.1617066114  0.499
2016 Gasnier B. Watching the Pulleys Turn while the Elevator Moves in a Secondary Transporter. Biophysical Journal. 111: 895-897. PMID 27602715 DOI: 10.1016/J.Bpj.2016.07.026  0.499
2014 Anne C, Gasnier B. Vesicular neurotransmitter transporters: mechanistic aspects. Current Topics in Membranes. 73: 149-74. PMID 24745982 DOI: 10.1016/B978-0-12-800223-0.00003-7  0.56
2013 Chapel A, Kieffer-Jaquinod S, Sagné C, Verdon Q, Ivaldi C, Mellal M, Thirion J, Jadot M, Bruley C, Garin J, Gasnier B, Journet A. An extended proteome map of the lysosomal membrane reveals novel potential transporters. Molecular & Cellular Proteomics : McP. 12: 1572-88. PMID 23436907 DOI: 10.1074/Mcp.M112.021980  0.436
2013 Martineau M, Shi T, Puyal J, Knolhoff AM, Dulong J, Gasnier B, Klingauf J, Sweedler JV, Jahn R, Mothet JP. Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3413-23. PMID 23426669 DOI: 10.1523/Jneurosci.3497-12.2013  0.393
2012 Jézégou A, Llinares E, Anne C, Kieffer-Jaquinod S, O'Regan S, Aupetit J, Chabli A, Sagné C, Debacker C, Chadefaux-Vekemans B, Journet A, André B, Gasnier B. Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy. Proceedings of the National Academy of Sciences of the United States of America. 109: E3434-43. PMID 23169667 DOI: 10.1073/Pnas.1211198109  0.505
2012 Jaenecke I, Boissel JP, Lemke M, Rupp J, Gasnier B, Closs EI. A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport. The Journal of Biological Chemistry. 287: 30853-60. PMID 22787143 DOI: 10.1074/Jbc.M112.350322  0.538
2012 Pietrancosta N, Anne C, Prescher H, Ruivo R, Sagné C, Debacker C, Bertrand HO, Brossmer R, Acher F, Gasnier B. Successful prediction of substrate-binding pocket in SLC17 transporter sialin. The Journal of Biological Chemistry. 287: 11489-97. PMID 22334707 DOI: 10.1074/Jbc.M111.313056  0.463
2012 Ruivo R, Bellenchi GC, Chen X, Zifarelli G, Sagné C, Debacker C, Pusch M, Supplisson S, Gasnier B. Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin. Proceedings of the National Academy of Sciences of the United States of America. 109: E210-7. PMID 22232659 DOI: 10.1073/Pnas.1115581109  0.683
2011 Savalas LR, Gasnier B, Damme M, Lübke T, Wrocklage C, Debacker C, Jézégou A, Reinheckel T, Hasilik A, Saftig P, Schröder B. Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. The Biochemical Journal. 439: 113-28. PMID 21692750 DOI: 10.1042/Bj20110166  0.431
2010 Sharifi A, Kousi M, Sagné C, Bellenchi GC, Morel L, Darmon M, Hulková H, Ruivo R, Debacker C, El Mestikawy S, Elleder M, Lehesjoki AE, Jalanko A, Gasnier B, Kyttälä A. Expression and lysosomal targeting of CLN7, a major facilitator superfamily transporter associated with variant late-infantile neuronal ceroid lipofuscinosis. Human Molecular Genetics. 19: 4497-514. PMID 20826447 DOI: 10.1093/Hmg/Ddq381  0.425
2010 Gailus S, Höhne W, Gasnier B, Nürnberg P, Fowler B, Rutsch F. Insights into lysosomal cobalamin trafficking: lessons learned from cblF disease. Journal of Molecular Medicine (Berlin, Germany). 88: 459-66. PMID 20174775 DOI: 10.1007/S00109-010-0601-X  0.338
2010 Amilhon B, Lepicard E, Renoir T, Mongeau R, Popa D, Poirel O, Miot S, Gras C, Gardier AM, Gallego J, Hamon M, Lanfumey L, Gasnier B, Giros B, El Mestikawy S. VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2198-210. PMID 20147547 DOI: 10.1523/Jneurosci.5196-09.2010  0.332
2009 Ruivo R, Anne C, Sagné C, Gasnier B. Molecular and cellular basis of lysosomal transmembrane protein dysfunction. Biochimica Et Biophysica Acta. 1793: 636-49. PMID 19146888 DOI: 10.1016/J.Bbamcr.2008.12.008  0.468
2009 Rutsch F, Gailus S, Miousse IR, Suormala T, Sagné C, Toliat MR, Nürnberg G, Wittkampf T, Buers I, Sharifi A, Stucki M, Becker C, Baumgartner M, Robenek H, Marquardt T, ... ... Gasnier B, et al. Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism. Nature Genetics. 41: 234-9. PMID 19136951 DOI: 10.1038/Ng.294  0.33
2009 Rutsch F, Gailus S, Racine-Miousse I, Suormala T, Sagne C, Wittkampf T, Robenek H, Marquardt T, Hoehne W, Gasnier B, Rosenblatt DS, Fowler B, Nuernberg P. 118. Identification of a novel lysosomal membrane protein mutated in the Cbl F defect of vitamin B12 metabolism Molecular Genetics and Metabolism. 96: S38. DOI: 10.1016/J.Ymgme.2008.11.119  0.308
2008 Sagné C, Gasnier B. Molecular physiology and pathophysiology of lysosomal membrane transporters. Journal of Inherited Metabolic Disease. 31: 258-66. PMID 18425435 DOI: 10.1007/s10545-008-0879-9  0.449
2008 Ruivo R, Sharifi A, Boubekeur S, Morin P, Anne C, Debacker C, Graziano JC, Sagné C, Gasnier B. Molecular pathogenesis of sialic acid storage diseases: insight gained from four missense mutations and a putative polymorphism of human sialin. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 100: 551-9. PMID 18399798 DOI: 10.1042/Bc20070166  0.417
2008 Gras C, Amilhon B, Lepicard EM, Poirel O, Vinatier J, Herbin M, Dumas S, Tzavara ET, Wade MR, Nomikos GG, Hanoun N, Saurini F, Kemel ML, Gasnier B, Giros B, et al. The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone. Nature Neuroscience. 11: 292-300. PMID 18278042 DOI: 10.1038/Nn2052  0.444
2007 Aubrey KR, Rossi FM, Ruivo R, Alboni S, Bellenchi GC, Le Goff A, Gasnier B, Supplisson S. The transporters GlyT2 and VIAAT cooperate to determine the vesicular glycinergic phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6273-81. PMID 17554001 DOI: 10.1523/Jneurosci.1024-07.2007  0.686
2007 Morin P, Sagné C, Gasnier B. Lysosomal membrane transport in the central nervous system Handbook of Neurochemistry and Molecular Neurobiology: Neural Membranes and Transport. 439-459. DOI: 10.1007/978-0-387-30380-2_22  0.398
2004 Morin P, Sagné C, Gasnier B. Functional characterization of wild-type and mutant human sialin. The Embo Journal. 23: 4560-70. PMID 15510212 DOI: 10.1038/Sj.Emboj.7600464  0.46
2004 Kalatzis V, Nevo N, Cherqui S, Gasnier B, Antignac C. Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin. Human Molecular Genetics. 13: 1361-71. PMID 15128704 DOI: 10.1093/Hmg/Ddh152  0.46
2004 Gasnier B. The SLC32 transporter, a key protein for the synaptic release of inhibitory amino acids. Pflã¼Gers Archiv : European Journal of Physiology. 447: 756-9. PMID 12750892 DOI: 10.1007/S00424-003-1091-2  0.579
2004 Boll M, Daniel H, Gasnier B. The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis. Pflã¼Gers Archiv : European Journal of Physiology. 447: 776-9. PMID 12748860 DOI: 10.1007/S00424-003-1073-4  0.543
2002 Jellali A, Stussi-Garaud C, Gasnier B, Rendon A, Sahel JA, Dreyfus H, Picaud S. Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. The Journal of Comparative Neurology. 449: 76-87. PMID 12115694 DOI: 10.1002/Cne.10272  0.433
2002 Gras C, Herzog E, Bellenchi GC, Bernard V, Ravassard P, Pohl M, Gasnier B, Giros B, El Mestikawy S. A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5442-51. PMID 12097496  0.377
2002 Marty S, Wehrlé R, Alvarez-Leefmans FJ, Gasnier B, Sotelo C. Postnatal maturation of Na+, K+, 2Cl- cotransporter expression and inhibitory synaptogenesis in the rat hippocampus: an immunocytochemical analysis. The European Journal of Neuroscience. 15: 233-45. PMID 11849291 DOI: 10.1046/J.0953-816X.2001.01854.X  0.396
2002 Gras C, Herzog E, Bellenchi GC, Bernard V, Ravassard P, Pohl M, Gasnier B, Giros B, Mestikawy SE. A Third Vesicular Glutamate Transporter Expressed by Cholinergic and Serotoninergic Neurons The Journal of Neuroscience. 22: 5442-5451. DOI: 10.1523/Jneurosci.22-13-05442.2002  0.468
2001 Herzog E, Bellenchi GC, Gras C, Bernard V, Ravassard P, Bedet C, Gasnier B, Giros B, El Mestikawy S. The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC181. PMID 11698619  0.429
2001 Kalatzis V, Cherqui S, Antignac C, Gasnier B. Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter. The Embo Journal. 20: 5940-9. PMID 11689434 DOI: 10.1093/Emboj/20.21.5940  0.551
2001 Kneussel M, Brandstätter JH, Gasnier B, Feng G, Sanes JR, Betz H. Gephyrin-independent clustering of postsynaptic GABA(A) receptor subtypes. Molecular and Cellular Neurosciences. 17: 973-82. PMID 11414787 DOI: 10.1006/Mcne.2001.0983  0.331
2001 Sagné C, Agulhon C, Ravassard P, Darmon M, Hamon M, El Mestikawy S, Gasnier B, Giros B. Identification and characterization of a lysosomal transporter for small neutral amino acids. Proceedings of the National Academy of Sciences of the United States of America. 98: 7206-11. PMID 11390972 DOI: 10.1073/Pnas.121183498  0.531
2001 Mayerhofer A, Höhne-Zell B, Gamel-Didelon K, Jung H, Redecker P, Grube D, Urbanski HF, Gasnier B, Fritschy JM, Gratzl M. Gamma-aminobutyric acid (GABA): a para- and/or autocrine hormone in the pituitary. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1089-91. PMID 11292677 DOI: 10.1096/Fj.00-0546Fje  0.369
2001 Herzog E, Bellenchi GC, Gras C, Bernard V, Ravassard P, Bedet C, Gasnier B, Giros B, Mestikawy SE. The Existence of a Second Vesicular Glutamate Transporter Specifies Subpopulations of Glutamatergic Neurons The Journal of Neuroscience. 21. DOI: 10.1523/Jneurosci.21-22-J0001.2001  0.5
2000 Dumoulin A, Lévi S, Riveau B, Gasnier B, Triller A. Formation of mixed glycine and GABAergic synapses in cultured spinal cord neurons. The European Journal of Neuroscience. 12: 3883-92. PMID 11069583 DOI: 10.1046/J.1460-9568.2000.00271.X  0.347
2000 Bedet C, Isambert MF, Henry JP, Gasnier B. Constitutive phosphorylation of the vesicular inhibitory amino acid transporter in rat central nervous system. Journal of Neurochemistry. 75: 1654-63. PMID 10987847 DOI: 10.1046/J.1471-4159.2000.0751654.X  0.458
2000 Gasnier B. The loading of neurotransmitters into synaptic vesicles. Biochimie. 82: 327-37. PMID 10865121 DOI: 10.1016/S0300-9084(00)00221-2  0.555
1999 Höcker M, John M, Anagnostopoulos J, Buhr HJ, Solimena M, Gasnier B, Henry JP, Wang TC, Wiedenmann B. Molecular dissection of regulated secretory pathways in human gastric enterochromaffin-like cells: an immunohistochemical analysis. Histochemistry and Cell Biology. 112: 205-14. PMID 10502067 DOI: 10.1007/S004180050408  0.377
1999 Dumoulin A, Rostaing P, Bedet C, Lévi S, Isambert MF, Henry JP, Triller A, Gasnier B. Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons. Journal of Cell Science. 112: 811-23. PMID 10036231  0.383
1998 Henry JP, Sagné C, Isambert MF, Gasnier B. Noncovalent and covalent labeling of vesicular monoamine transporter with tetrabenazine and ketanserin derivatives; purification of photolabeled protein. Methods in Enzymology. 296: 73-83. PMID 9779441 DOI: 10.1016/S0076-6879(98)96007-4  0.51
1998 Henry JP, Sagné C, Bedet C, Gasnier B. The vesicular monoamine transporter: from chromaffin granule to brain. Neurochemistry International. 32: 227-46. PMID 9587917 DOI: 10.1016/S0197-0186(97)00092-2  0.505
1998 Henry JP, Sagné C, Botton D, Isambert MF, Gasnier B. Molecular pharmacology of the vesicular monoamine transporter. Advances in Pharmacology (San Diego, Calif.). 42: 236-9. PMID 9327887 DOI: 10.1016/S1054-3589(08)60736-X  0.45
1997 Sagné C, El Mestikawy S, Isambert MF, Hamon M, Henry JP, Giros B, Gasnier B. Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases. Febs Letters. 417: 177-83. PMID 9395291 DOI: 10.1016/S0014-5793(97)01279-9  0.488
1997 Sagné C, Isambert MF, Vandekerckhove J, Henry JP, Gasnier B. The photoactivatable inhibitor 7-azido-8-iodoketanserin labels the N terminus of the vesicular monoamine transporter from bovine chromaffin granules. Biochemistry. 36: 3345-52. PMID 9116013 DOI: 10.1021/Bi9623439  0.451
1996 Sagné C, Isambert MF, Henry JP, Gasnier B. SDS-resistant aggregation of membrane proteins: application to the purification of the vesicular monoamine transporter. The Biochemical Journal. 316: 825-31. PMID 8670158 DOI: 10.1042/Bj3160825  0.444
1994 Gasnier B, Krejci E, Botton D, Massoulié J, Henry JP. Expression of a bovine vesicular monoamine transporter in COS cells. Febs Letters. 342: 225-9. PMID 8150075 DOI: 10.1016/0014-5793(94)80506-7  0.532
1994 Henry JP, Gasnier B, Desnos C, Scherman D, Krejci E, Massoulié J. The catecholamine transporter of adrenal medulla chromaffin granules. Annals of the New York Academy of Sciences. 733: 185-92. PMID 7978866 DOI: 10.1111/J.1749-6632.1994.Tb17268.X  0.496
1994 Henry JP, Botton D, Sagne C, Isambert MF, Desnos C, Blanchard V, Raisman-Vozari R, Krejci E, Massoulie J, Gasnier B. Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules. The Journal of Experimental Biology. 196: 251-62. PMID 7823026  0.477
1993 Krejci E, Gasnier B, Botton D, Isambert MF, Sagné C, Gagnon J, Massoulié J, Henry JP. Expression and regulation of the bovine vesicular monoamine transporter gene. Febs Letters. 335: 27-32. PMID 7902299 DOI: 10.1016/0014-5793(93)80432-T  0.479
1992 Isambert MF, Gasnier B, Botton D, Henry JP. Characterization and purification of the monoamine transporter of bovine chromaffin granules. Biochemistry. 31: 1980-6. PMID 1536840 DOI: 10.1021/Bi00122A012  0.445
1992 Gasnier B, Isambert M, Sagmé C, Desnos C, Scherman D, Henry J. The monoamine transporter of chromaffin granules: Purification and regulation Neurochemistry International. 21: Q17. DOI: 10.1016/0197-0186(92)91851-M  0.488
1989 Isambert MF, Gasnier B, Laduron PM, Henry JP. Photoaffinity labeling of the monoamine transporter of bovine chromaffin granules and other monoamine storage vesicles using 7-azido-8-[125I]iodoketanserin. Biochemistry. 28: 2265-70. PMID 2719952 DOI: 10.1021/Bi00431A044  0.437
1987 Gasnier B. Characterization of low- and high-affinity glucose transports in the yeast Kluyveromyces marxianus. Biochimica Et Biophysica Acta. 903: 425-33. PMID 3663655 DOI: 10.1016/0005-2736(87)90049-6  0.402
1987 Gasnier B, Scherman D, Henry JP. Inactivation of the catecholamine transporter during the preparation of chromaffin granule membrane 'ghosts'. Febs Letters. 222: 215-9. PMID 3653399 DOI: 10.1016/0014-5793(87)80222-3  0.477
1987 Gasnier B, Ellory JC, Henry JP. Functional molecular mass of binding sites for [3H]dihydrotetrabenazine and [3H]reserpine and of dopamine beta-hydroxylase and cytochrome b561 from chromaffin granule membrane as determined by radiation inactivation. European Journal of Biochemistry / Febs. 165: 73-8. PMID 3569299 DOI: 10.1111/J.1432-1033.1987.Tb11195.X  0.333
1987 Henry JP, Gasnier B, Roisin MP, Isambert MF, Scherman D. Molecular pharmacology of the monoamine transporter of the chromaffin granule membrane. Annals of the New York Academy of Sciences. 493: 194-206. PMID 3296907 DOI: 10.1111/J.1749-6632.1987.Tb27201.X  0.488
1986 Gasnier B, Roisin MP, Scherman D, Coornaert S, Desplanches G, Henry JP. Uptake of meta-iodobenzylguanidine by bovine chromaffin granule membranes. Molecular Pharmacology. 29: 275-80. PMID 3951433  0.451
1986 Henry JP, Scherman D, Roisin MP, Gasnier B, Isambert MF. [Molecular pharmacology of the catecholamine transporter of chromaffin granules from the bovine adrenal medulla]. Biochimie. 68: 451-8. PMID 3017452 DOI: 10.1016/S0300-9084(86)80012-8  0.383
1985 Gasnier B, Scherman D, Henry JP. Dicyclohexylcarbodiimide inhibits the monoamine carrier of bovine chromaffin granule membrane. Biochemistry. 24: 1239-44. PMID 2937444 DOI: 10.1021/Bi00326A028  0.387
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