Bruno Giros - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Molecular Neurobiology, Psychiatry, Neuropsychopharmacology

194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bonnavion P, Varin C, Fakhfouri G, Martinez Olondo P, De Groote A, Cornil A, Lorenzo Lopez R, Pozuelo Fernandez E, Isingrini E, Rainer Q, Xu K, Tzavara E, Vigneault E, Dumas S, de Kerchove d'Exaerde A, ... Giros B, et al. Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs. Nature Neuroscience. PMID 38965445 DOI: 10.1038/s41593-024-01694-4  0.716
2023 Rocchetti J, Fasano C, Dal-Bo G, Guma E, El Mestikawy S, Wong TP, Fakhfouri G, Giros B. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. Plos One. 18: e0289770. PMID 37624765 DOI: 10.1371/journal.pone.0289770  0.81
2023 Isingrini E, Guinaudie C, Perret L, Guma E, Gorgievski V, Blum ID, Colby-Milley J, Bairachnaya M, Mella S, Adamantidis A, Storch KF, Giros B. Behavioral and Transcriptomic Changes Following Brain-Specific Loss of Noradrenergic Transmission. Biomolecules. 13. PMID 36979445 DOI: 10.3390/biom13030511  0.725
2022 Petrelli F, Zehnder T, Laugeray A, Mondoloni S, Calì C, Pucci L, Molinero Perez A, Bondiolotti BM, De Oliveira Figueiredo E, Dallerac G, Déglon N, Giros B, Magrassi L, Mothet JP, Mameli M, et al. Disruption of Astrocyte-Dependent Dopamine Control in the Developing Medial Prefrontal Cortex Leads to Excessive Grooming in Mice. Biological Psychiatry. PMID 36958999 DOI: 10.1016/j.biopsych.2022.11.018  0.325
2021 Rebeillard F, De Gois S, Pietrancosta N, Mai TH, Lai-Kuen R, Kieffer BL, Giros B, Massart R, Darmon M, Diaz J. The Orphan GPCR Receptor, GPR88, Interacts with Nuclear Protein Partners in the Cerebral Cortex. Cerebral Cortex (New York, N.Y. : 1991). PMID 34247243 DOI: 10.1093/cercor/bhab224  0.755
2020 Bhardwaj SK, Cui Q, Moquin L, Gratton A, Giros B, Srivastava LK. Mice with dopaminergic neuron-specific deletion of DTNBP-1 gene show blunted nucleus accumbens dopamine release and associated behaviors. Neuropharmacology. 108440. PMID 33340529 DOI: 10.1016/j.neuropharm.2020.108440  0.373
2019 Poirel O, Mamer LE, Herman MA, Arnulf-Kempcke M, Kervern M, Potier B, Miot S, Wang J, Favre-Besse FC, Brabet I, Laras Y, Bertrand HO, Acher F, Pin JP, Puel JL, ... Giros B, et al. LSP5-2157 a new inhibitor of vesicular glutamate transporters. Neuropharmacology. 107902. PMID 31811873 DOI: 10.1016/J.Neuropharm.2019.107902  0.745
2019 Orrico-Sanchez A, Chausset-Boissarie L, Alves de Sousa R, Coutens B, Rezai Amin S, Vialou V, Louis F, Hessani A, Dansette PM, Zornoza T, Gruszczynski C, Giros B, Guiard BP, Acher F, Pietrancosta N, et al. Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression. Molecular Psychiatry. PMID 31619760 DOI: 10.1038/S41380-019-0548-4  0.658
2019 Cavarec F, Krauss P, Witkowski T, Broisat A, Ghezzi C, De Gois S, Giros B, Depaulis A, Deransart C. Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis. Epilepsia. PMID 31535376 DOI: 10.1111/Epi.16342  0.79
2019 Giguère N, Delignat-Lavaud B, Herborg F, Voisin A, Li Y, Jacquemet V, Anand-Srivastava M, Gether U, Giros B, Trudeau LÉ. Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout. Plos Genetics. 15: e1008352. PMID 31449520 DOI: 10.1371/Journal.Pgen.1008352  0.38
2019 Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration. Scientific Reports. 9: 7850. PMID 31127135 DOI: 10.1038/S41598-019-43955-4  0.811
2019 Bimpisidis Z, König N, Stagkourakis S, Zell V, Vlcek B, Dumas S, Giros B, Broberger C, Hnasko TS, Wallén-Mackenzie Å. The NeuroD6 subtype of VTA neurons contributes to psychostimulant sensitization and behavioral reinforcement. Eneuro. PMID 31097625 DOI: 10.1523/ENEURO.0066-19.2019  0.308
2019 Mongrédien R, Erdozain AM, Dumas S, Cutando L, Del Moral AN, Puighermanal E, Rezai Amin S, Giros B, Valjent E, Meana JJ, Gautron S, Callado LF, Fabre V, Vialou V. Cartography of hevin-expressing cells in the adult brain reveals prominent expression in astrocytes and parvalbumin neurons. Brain Structure & Function. PMID 30656447 DOI: 10.1007/S00429-019-01831-X  0.665
2018 Nair AG, Castro LRV, El Khoury M, Gorgievski V, Giros B, Tzavara ET, Hellgren-Kotaleski J, Vincent P. The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia. Neuropharmacology. PMID 30468798 DOI: 10.1016/J.Neuropharm.2018.11.029  0.722
2018 Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, ... ... Giros B, et al. Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments. Molecular Psychiatry. PMID 30127471 DOI: 10.1038/S41380-018-0226-Y  0.442
2018 Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, ... ... Giros B, et al. Antidepressive effects of targeting ELK-1 signal transduction. Nature Medicine. PMID 29736027 DOI: 10.1038/S41591-018-0011-0  0.774
2018 Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage. PMID 29704613 DOI: 10.1016/J.Neuroimage.2018.04.054  0.806
2017 Dos Santos M, Cahill EN, Bo GD, Vanhoutte P, Caboche J, Giros B, Heck N. Cocaine increases dopaminergic connectivity in the nucleus accumbens. Brain Structure & Function. PMID 29027032 DOI: 10.1007/S00429-017-1532-X  0.428
2017 Isingrini E, Guinaudie C, C Perret L, Rainer Q, Moquin L, Gratton A, Giros B. Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson's disease motor symptoms without neuronal degeneration in adult mice. Scientific Reports. 7: 12432. PMID 28963508 DOI: 10.1038/S41598-017-12810-9  0.767
2017 Erdozain AM, De Gois S, Bernard V, Gorgievski V, Pietrancosta N, Dumas S, Macedo CE, Vanhoutte P, Ortega JE, Meana JJ, Tzavara ET, Vialou V, Giros B. Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28905875 DOI: 10.1038/Npp.2017.217  0.838
2017 Xu Y, Lu Y, Xu P, Mangieri LR, Isingrini E, Xu Y, Giros B, Tong Q. VMAT2-Mediated Neurotransmission from Midbrain Leptin Receptor Neurons in Feeding Regulation. Eneuro. 4. PMID 28560316 DOI: 10.1523/ENEURO.0083-17.2017  0.301
2017 Fasano C, Rocchetti J, Pietrajtis K, Zander JF, Manseau F, Sakae DY, Marcus-Sells M, Ramet L, Morel LJ, Carrel D, Dumas S, Bolte S, Bernard V, Vigneault E, Goutagny R, ... ... Giros B, et al. Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells. Frontiers in Cellular Neuroscience. 11: 140. PMID 28559797 DOI: 10.3389/Fncel.2017.00140  0.737
2017 Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. 695. Resilience against Chronic Stress is Mediated by Noradrenergic Regulation of the Ventral Tegmental Area Biological Psychiatry. 81: S282. DOI: 10.1016/J.Biopsych.2017.02.762  0.765
2017 Farley S, Grenier J, Gorgievski V, Barbe A, Jaworski W, Bochereau A, Macedo C, Ghandour S, Huebner N, Bienert T, Henning J, Massaad C, Giros B, Harsan L, Tzavara E. 109. From Early Life Adversity to Adolescence Depression: White Matter Remodelling in a Translational Animal Model Biological Psychiatry. 81: S46. DOI: 10.1016/J.Biopsych.2017.02.121  0.505
2016 Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nature Neuroscience. PMID 26878672 DOI: 10.1038/Nn.4245  0.8
2016 Erdozain A, De Gois S, Bernard V, Gorgievski V, Pietrancosta N, Macedo C, Vanhoutte P, Ortega J, Meana J, Tzavara E, Vialou V, Giros B. Snapin control of the dopamine transporter trafficking regulates amphetamine effect on mice European Neuropsychopharmacology. 26: S221-S222. DOI: 10.1016/S0924-977X(16)31076-8  0.472
2015 Isingrini E, Perret L, Rainer Q, Sagueby S, Moquin L, Gratton A, Giros B. Selective genetic disruption of dopaminergic, serotonergic and noradrenergic neurotransmission: insights into motor, emotional and addictive behaviour. Journal of Psychiatry & Neuroscience : Jpn. 41: 150028. PMID 26505143 DOI: 10.1503/Jpn.150028  0.769
2015 Pilorge M, Fassier C, Le Corronc H, Potey A, Bai J, De Gois S, Delaby E, Assouline B, Guinchat V, Devillard F, Delorme R, Nygren G, Råstam M, Meier JC, Otani S, ... ... Giros B, et al. Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Molecular Psychiatry. PMID 26370147 DOI: 10.1038/Mp.2015.139  0.775
2015 Sakae DY, Marti F, Lecca S, Vorspan F, Martín-García E, Morel LJ, Henrion A, Gutiérrez-Cuesta J, Besnard A, Heck N, Herzog E, Bolte S, Prado VF, Prado MA, Bellivier F, ... ... Giros B, et al. The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens. Molecular Psychiatry. 20: 1448-59. PMID 26239290 DOI: 10.1038/Mp.2015.104  0.783
2015 De Gois S, Slama P, Pietrancosta N, Erdozain AM, Louis F, Bouvrais-Veret C, Daviet L, Giros B. Ctr9, a protein in the transcription complex Paf1, regulates dopamine transporter activity at the plasma membrane. The Journal of Biological Chemistry. PMID 26048990 DOI: 10.1074/Jbc.M115.646315  0.813
2015 Doly S, Shirvani H, Gäta G, Meye FJ, Emerit MB, Enslen H, Achour L, Pardo-Lopez L, Yang SK, Armand V, Gardette R, Giros B, Gassmann M, Bettler B, Mameli M, et al. GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper. Molecular Psychiatry. PMID 26033241 DOI: 10.1038/Mp.2015.72  0.339
2015 Couroussé T, Bacq A, Belzung C, Guiard B, Balasse L, Louis F, Le Guisquet AM, Gardier AM, Schinkel AH, Giros B, Gautron S. Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling. Molecular Psychiatry. 20: 889-900. PMID 25092247 DOI: 10.1038/Mp.2014.86  0.332
2015 Rocchetti J, Isingrini E, Dal Bo G, Sagheby S, Menegaux A, Tronche F, Levesque D, Moquin L, Gratton A, Wong TP, Rubinstein M, Giros B. Presynaptic D2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus. Biological Psychiatry. 77: 513-25. PMID 24742619 DOI: 10.1016/J.Biopsych.2014.03.013  0.803
2015 Blot K, Kimura S, Bai J, Kemp A, Manahan-Vaughan D, Giros B, Tzavara E, Otani S. Modulation of hippocampus-prefrontal cortex synaptic transmission and disruption of executive cognitive functions by MK-801. Cerebral Cortex (New York, N.Y. : 1991). 25: 1348-61. PMID 24304584 DOI: 10.1093/Cercor/Bht329  0.332
2015 Sakae DY, Marti F, Lecca S, Vorspan F, Martín-García E, Morel LJ, Henrion A, Gutiérrez-Cuesta J, Besnard A, Heck N, Herzog E, Bolte S, Prado VF, Prado MAM, Bellivier F, ... ... Giros B, et al. The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens Molecular Psychiatry. DOI: 10.1038/mp.2015.104  0.727
2015 Gorgievski V, Tzavara ET, Giros B. Study of dopamine receptor and dopamine transporter networks in mice Neuromethods. 96: 305-328. DOI: 10.1007/978-1-4939-2196-6_17  0.348
2014 Blum ID, Zhu L, Moquin L, Kokoeva MV, Gratton A, Giros B, Storch KF. A highly tunable dopaminergic oscillator generates ultradian rhythms of behavioral arousal. Elife. 3. PMID 25546305 DOI: 10.7554/Elife.05105  0.426
2014 Bai J, Blot K, Tzavara E, Nosten-Bertrand M, Giros B, Otani S. Inhibition of dopamine transporter activity impairs synaptic depression in rat prefrontal cortex through over-stimulation of D1 receptors. Cerebral Cortex (New York, N.Y. : 1991). 24: 945-55. PMID 23236206 DOI: 10.1093/Cercor/Bhs376  0.422
2013 Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, ... ... Giros B, et al. dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Translational Psychiatry. 3: e338. PMID 24346136 DOI: 10.1038/Tp.2013.105  0.522
2013 Lejeune S, Dourmap N, Martres MP, Giros B, Daugé V, Naudon L. The dopamine D1 receptor agonist SKF 38393 improves temporal order memory performance in maternally deprived rats. Neurobiology of Learning and Memory. 106: 268-73. PMID 24140426 DOI: 10.1016/J.Nlm.2013.10.005  0.39
2013 Germain J, Bruel-Jungerman E, Grannec G, Denis C, Lepousez G, Giros B, Francis F, Nosten-Bertrand M. Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects. Plos One. 8: e74992. PMID 24073232 DOI: 10.1371/Journal.Pone.0074992  0.323
2013 Diaz SL, Narboux-Nême N, Trowbridge S, Scotto-Lomassese S, Kleine Borgmann FB, Jessberger S, Giros B, Maroteaux L, Deneris E, Gaspar P. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European Journal of Neuroscience. 38: 2650-8. PMID 23841816 DOI: 10.1111/Ejn.12297  0.313
2013 Narboux-Nême N, Angenard G, Mosienko V, Klempin F, Pitychoutis PM, Deneris E, Bader M, Giros B, Alenina N, Gaspar P. Postnatal growth defects in mice with constitutive depletion of central serotonin. Acs Chemical Neuroscience. 4: 171-81. PMID 23336056 DOI: 10.1021/Cn300165X  0.311
2013 Barth V, Need AB, Tzavara ET, Giros B, Overshiner C, Gleason SD, Wade M, Johansson AM, Perry K, Nomikos GG, Witkin JM. In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder. The Journal of Pharmacology and Experimental Therapeutics. 344: 501-10. PMID 23197772 DOI: 10.1124/Jpet.112.198895  0.411
2012 Fournet V, de Lavilléon G, Schweitzer A, Giros B, Andrieux A, Martres MP. Both chronic treatments by epothilone D and fluoxetine increase the short-term memory and differentially alter the mood status of STOP/MAP6 KO mice. Journal of Neurochemistry. 123: 982-96. PMID 23013328 DOI: 10.1111/Jnc.12027  0.387
2012 Baudin A, Blot K, Verney C, Estevez L, Santamaria J, Gressens P, Giros B, Otani S, Daugé V, Naudon L. Maternal deprivation induces deficits in temporal memory and cognitive flexibility and exaggerates synaptic plasticity in the rat medial prefrontal cortex. Neurobiology of Learning and Memory. 98: 207-14. PMID 22922490 DOI: 10.1016/J.Nlm.2012.08.004  0.317
2012 Haenisch B, Drescher E, Thiemer L, Xin H, Giros B, Gautron S, Bönisch H. Interaction of antidepressant and antipsychotic drugs with the human organic cation transporters hOCT1, hOCT2 and hOCT3. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 1017-23. PMID 22806583 DOI: 10.1007/S00210-012-0781-8  0.339
2012 El Khoury MA, Gorgievski V, Moutsimilli L, Giros B, Tzavara ET. Interactions between the cannabinoid and dopaminergic systems: evidence from animal studies. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 36-50. PMID 22300746 DOI: 10.1016/J.Pnpbp.2011.12.005  0.802
2012 Berthet A, Bezard E, Porras G, Fasano S, Barroso-Chinea P, Dehay B, Martinez A, Thiolat ML, Nosten-Bertrand M, Giros B, Baufreton J, Li Q, Bloch B, Martin-Negrier ML. L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 681-91. PMID 22238104 DOI: 10.1523/Jneurosci.1541-11.2012  0.4
2012 Fournet V, Schweitzer A, Chevarin C, Deloulme JC, Hamon M, Giros B, Andrieux A, Martres MP. The deletion of STOP/MAP6 protein in mice triggers highly altered mood and impaired cognitive performances. Journal of Neurochemistry. 121: 99-114. PMID 22146001 DOI: 10.1111/J.1471-4159.2011.07615.X  0.543
2012 Farley S, Dumas S, El Mestikawy S, Giros B. Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. Neuropharmacology. 62: 503-17. PMID 21945287 DOI: 10.1016/J.Neuropharm.2011.09.010  0.781
2012 Bacq A, Balasse L, Biala G, Guiard B, Gardier AM, Schinkel A, Louis F, Vialou V, Martres MP, Chevarin C, Hamon M, Giros B, Gautron S. Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response. Molecular Psychiatry. 17: 926-39. PMID 21769100 DOI: 10.1038/Mp.2011.87  0.806
2012 El Mestikawy S, Fasano C, Daumas S, Giros B, Sakae D, Ramet L. S.12.04 Regulation of ‘non-glutamatergic’ transmission by the vesicular glutamate transporter VGLUT3 European Neuropsychopharmacology. 22: S129. DOI: 10.1016/S0924-977X(12)70157-8  0.363
2011 Narboux-Nême N, Sagné C, Doly S, Diaz SL, Martin CB, Angenard G, Martres MP, Giros B, Hamon M, Lanfumey L, Gaspar P, Mongeau R. Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2538-50. PMID 21814181 DOI: 10.1038/Npp.2011.142  0.528
2011 Charron G, Doudnikoff E, Laux A, Berthet A, Porras G, Canron MH, Barroso-Chinea P, Li Q, Qin C, Nosten-Bertrand M, Giros B, Delalande F, Van Dorsselaer A, Vital A, Goumon Y, et al. Endogenous morphine-like compound immunoreactivity increases in parkinsonism. Brain : a Journal of Neurology. 134: 2321-38. PMID 21742735 DOI: 10.1093/Brain/Awr166  0.32
2011 Naef L, Moquin L, Dal Bo G, Giros B, Gratton A, Walker CD. Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring. Neuroscience. 176: 225-36. PMID 21187125 DOI: 10.1016/J.Neuroscience.2010.12.037  0.388
2010 Fournet V, Jany M, Fabre V, Chali F, Orsal D, Schweitzer A, Andrieux A, Messanvi F, Giros B, Hamon M, Lanfumey L, Deloulme JC, Martres MP. The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network. Journal of Neurochemistry. 115: 1579-94. PMID 20969568 DOI: 10.1111/J.1471-4159.2010.07064.X  0.526
2010 Pietrancosta N, Kessler A, Favre-Besse FC, Triballeau N, Quentin T, Giros B, El Mestikawy S, Acher FC. Rose Bengal analogs and vesicular glutamate transporters (VGLUTs). Bioorganic & Medicinal Chemistry. 18: 6922-33. PMID 20708942 DOI: 10.1016/J.Bmc.2010.06.069  0.741
2010 Amphoux A, Millan MJ, Cordi A, Bönisch H, Vialou V, Mannoury la Cour C, Dupuis DS, Giros B, Gautron S. Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha 1- and alpha 2-adrenoceptor subtypes. European Journal of Pharmacology. 634: 1-9. PMID 20170649 DOI: 10.1016/J.Ejphar.2010.02.012  0.657
2010 Amilhon B, Lepicard E, Renoir T, Mongeau R, Popa D, Poirel O, Miot S, Gras C, Gardier AM, Gallego J, Hamon M, Lanfumey L, Gasnier B, Giros B, El Mestikawy S. VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2198-210. PMID 20147547 DOI: 10.1523/Jneurosci.5196-09.2010  0.77
2010 Farley S, Apazoglou K, Witkin JM, Giros B, Tzavara ET. Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1207-18. PMID 20059803 DOI: 10.1017/S1461145709991076  0.583
2010 Morice E, Denis C, Giros B, Nosten-Bertrand M. Evidence of long-term expression of behavioral sensitization to both cocaine and ethanol in dopamine transporter knockout mice. Psychopharmacology. 208: 57-66. PMID 19937000 DOI: 10.1007/S00213-009-1707-0  0.774
2010 Blot K, Kimura S, Kemp A, Manahan-Vaughan D, Giros B, Otani S. The Effect Of Non-Competitive Nmda Receptor Antagonist Mk801 On Hippocampus-Prefrontal Cortex Synaptic Responses And Executive Cognitive Function In Rats Schizophrenia Research. 117: 393-393. DOI: 10.1016/J.Schres.2010.02.710  0.306
2008 Ruel J, Emery S, Nouvian R, Bersot T, Amilhon B, Van Rybroek JM, Rebillard G, Lenoir M, Eybalin M, Delprat B, Sivakumaran TA, Giros B, El Mestikawy S, Moser T, Smith RJ, et al. Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice. American Journal of Human Genetics. 83: 278-92. PMID 18674745 DOI: 10.1016/J.Ajhg.2008.07.008  0.741
2008 Vialou V, Balasse L, Callebert J, Launay JM, Giros B, Gautron S. Altered aminergic neurotransmission in the brain of organic cation transporter 3-deficient mice. Journal of Neurochemistry. 106: 1471-82. PMID 18513366 DOI: 10.1111/J.1471-4159.2008.05506.X  0.701
2008 Gras C, Amilhon B, Lepicard EM, Poirel O, Vinatier J, Herbin M, Dumas S, Tzavara ET, Wade MR, Nomikos GG, Hanoun N, Saurini F, Kemel ML, Gasnier B, Giros B, et al. The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone. Nature Neuroscience. 11: 292-300. PMID 18278042 DOI: 10.1038/Nn2052  0.82
2008 Mathieu F, Miot S, Etain B, El Khoury MA, Chevalier F, Bellivier F, Leboyer M, Giros B, Tzavara ET. Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder. Behavioral and Brain Functions : Bbf. 4: 2. PMID 18201382 DOI: 10.1186/1744-9081-4-2  0.66
2008 Bouvrais-Veret C, Weiss S, Hanoun N, Andrieux A, Schweitzer A, Job D, Hamon M, Giros B, Martres MP. Microtubule-associated STOP protein deletion triggers restricted changes in dopaminergic neurotransmission. Journal of Neurochemistry. 104: 745-56. PMID 18199119 DOI: 10.1111/J.1471-4159.2007.05025.X  0.832
2008 Moutsimilli L, Farley S, El Khoury MA, Chamot C, Sibarita JB, Racine V, El Mestikawy S, Mathieu F, Dumas S, Giros B, Tzavara ET. Antipsychotics increase vesicular glutamate transporter 2 (VGLUT2) expression in thalamolimbic pathways. Neuropharmacology. 54: 497-508. PMID 18155072 DOI: 10.1016/J.Neuropharm.2007.10.022  0.808
2008 Herzog CJ, Miot S, Mansuy IM, Giros B, Tzavara ET. Chronic valproate normalizes behavior in mice overexpressing calcineurin. European Journal of Pharmacology. 580: 153-60. PMID 18021766 DOI: 10.1016/J.Ejphar.2007.10.050  0.583
2008 Kashani A, Lepicard E, Poirel O, Videau C, David JP, Fallet-Bianco C, Simon A, Delacourte A, Giros B, Epelbaum J, Betancur C, El Mestikawy S. Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease. Neurobiology of Aging. 29: 1619-30. PMID 17531353 DOI: 10.1016/J.Neurobiolaging.2007.04.010  0.703
2007 Khelfaoui M, Denis C, van Galen E, de Bock F, Schmitt A, Houbron C, Morice E, Giros B, Ramakers G, Fagni L, Chelly J, Nosten-Bertrand M, Billuart P. Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9439-50. PMID 17728457 DOI: 10.1523/Jneurosci.2029-07.2007  0.752
2007 Bouvrais-Veret C, Weiss S, Andrieux A, Schweitzer A, McIntosh JM, Job D, Giros B, Martres MP. Sustained increase of alpha7 nicotinic receptors and choline-induced improvement of learning deficit in STOP knock-out mice. Neuropharmacology. 52: 1691-700. PMID 17512560 DOI: 10.1016/J.Neuropharm.2007.03.015  0.787
2007 Vazquez V, Weiss S, Giros B, Martres MP, Daugé V. Maternal deprivation and handling modify the effect of the dopamine D3 receptor agonist, BP 897 on morphine-conditioned place preference in rats. Psychopharmacology. 193: 475-86. PMID 17492273 DOI: 10.1007/S00213-007-0789-9  0.531
2007 Weiss S, Tzavara ET, Davis RJ, Nomikos GG, Michael McIntosh J, Giros B, Martres MP. Functional alterations of nicotinic neurotransmission in dopamine transporter knock-out mice. Neuropharmacology. 52: 1496-508. PMID 17433376 DOI: 10.1016/J.Neuropharm.2007.02.002  0.55
2007 Weiss S, Nosten-Bertrand M, McIntosh JM, Giros B, Martres MP. Nicotine improves cognitive deficits of dopamine transporter knockout mice without long-term tolerance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2465-78. PMID 17375139 DOI: 10.1038/Sj.Npp.1301385  0.534
2007 Morice E, Billard JM, Denis C, Mathieu F, Betancur C, Epelbaum J, Giros B, Nosten-Bertrand M. Parallel loss of hippocampal LTD and cognitive flexibility in a genetic model of hyperdopaminergia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2108-16. PMID 17342172 DOI: 10.1038/Sj.Npp.1301354  0.804
2007 Crozatier C, Farley S, Mansuy IM, Dumas S, Giros B, Tzavara ET. Calcineurin (protein phosphatase 2B) is involved in the mechanisms of action of antidepressants. Neuroscience. 144: 1470-6. PMID 17207580 DOI: 10.1016/J.Neuroscience.2006.11.030  0.628
2007 Vialou V, Balasse L, Dumas S, Giros B, Gautron S. Neurochemical characterization of pathways expressing plasma membrane monoamine transporter in the rat brain. Neuroscience. 144: 616-22. PMID 17110048 DOI: 10.1016/J.Neuroscience.2006.09.058  0.719
2007 Kashani A, Betancur C, Giros B, Hirsch E, El Mestikawy S. Altered expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in Parkinson disease. Neurobiology of Aging. 28: 568-78. PMID 16563567 DOI: 10.1016/J.Neurobiolaging.2006.02.010  0.729
2007 Lepicard E, Poirel O, Kashani A, Amilhon B, Hirsch E, Epelbaum J, David JP, Delacourte J, Giros B, Betancur C, Mestikawy SE. P.5.b.005 Vesicular glutamate transporters in pathologies of the central nervous system European Neuropsychopharmacology. 17. DOI: 10.1016/S0924-977X(07)70827-1  0.334
2006 Vazquez V, Giros B, Daugé V. Maternal deprivation specifically enhances vulnerability to opiate dependence. Behavioural Pharmacology. 17: 715-24. PMID 17110797 DOI: 10.1097/Fbp.0B013E3280116E6F  0.314
2006 Vinatier J, Herzog E, Plamont MA, Wojcik SM, Schmidt A, Brose N, Daviet L, El Mestikawy S, Giros B. Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis. Journal of Neurochemistry. 97: 1111-25. PMID 16606361 DOI: 10.1111/J.1471-4159.2006.03821.X  0.798
2006 Amphoux A, Vialou V, Drescher E, Brüss M, Mannoury La Cour C, Rochat C, Millan MJ, Giros B, Bönisch H, Gautron S. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology. 50: 941-52. PMID 16581093 DOI: 10.1016/J.Neuropharm.2006.01.005  0.674
2006 Tzavara ET, Li DL, Moutsimilli L, Bisogno T, Di Marzo V, Phebus LA, Nomikos GG, Giros B. Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. Biological Psychiatry. 59: 508-15. PMID 16199010 DOI: 10.1016/J.Biopsych.2005.08.019  0.823
2005 Gras C, Vinatier J, Amilhon B, Guerci A, Christov C, Ravassard P, Giros B, El Mestikawy S. Developmentally regulated expression of VGLUT3 during early post-natal life. Neuropharmacology. 49: 901-11. PMID 16182324 DOI: 10.1016/J.Neuropharm.2005.07.023  0.795
2005 Moutsimilli L, Farley S, Dumas S, El Mestikawy S, Giros B, Tzavara ET. Selective cortical VGLUT1 increase as a marker for antidepressant activity. Neuropharmacology. 49: 890-900. PMID 16111724 DOI: 10.1016/J.Neuropharm.2005.06.017  0.797
2005 Guerriero RM, Rajadhyaksha A, Crozatier C, Giros B, Nosten-Bertrand M, Kosofsky BE. Augmented constitutive CREB expression in the nucleus accumbens and striatum may contribute to the altered behavioral response to cocaine of adult mice exposed to cocaine in utero. Developmental Neuroscience. 27: 235-48. PMID 16046859 DOI: 10.1159/000085997  0.335
2005 Vazquez V, Farley S, Giros B, Daugé V. Maternal deprivation increases behavioural reactivity to stressful situations in adulthood: suppression by the CCK2 antagonist L365,260. Psychopharmacology. 181: 706-13. PMID 16032413 DOI: 10.1007/S00213-005-0029-0  0.546
2005 Biala G, Betancur C, Mansuy IM, Giros B. The reinforcing effects of chronic D-amphetamine and morphine are impaired in a line of memory-deficient mice overexpressing calcineurin. The European Journal of Neuroscience. 21: 3089-96. PMID 15978018 DOI: 10.1111/J.1460-9568.2005.04132.X  0.651
2005 Morice E, Denis C, Macario A, Giros B, Nosten-Bertrand M. Constitutive hyperdopaminergia is functionally associated with reduced behavioral lateralization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 575-81. PMID 15354185 DOI: 10.1038/Sj.Npp.1300570  0.786
2004 Herzog E, Landry M, Buhler E, Bouali-Benazzouz R, Legay C, Henderson CE, Nagy F, Dreyfus P, Giros B, El Mestikawy S. Expression of vesicular glutamate transporters, VGLUT1 and VGLUT2, in cholinergic spinal motoneurons. The European Journal of Neuroscience. 20: 1752-60. PMID 15379996 DOI: 10.1111/J.1460-9568.2004.03628.X  0.731
2004 Morice E, Denis C, Giros B, Nosten-Bertrand M. Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background. The European Journal of Neuroscience. 20: 120-6. PMID 15245485 DOI: 10.1111/J.1460-9568.2004.03465.X  0.788
2004 Vialou V, Amphoux A, Zwart R, Giros B, Gautron S. Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2846-51. PMID 15028779 DOI: 10.1523/Jneurosci.5147-03.2004  0.682
2004 Herzog E, Gilchrist J, Gras C, Muzerelle A, Ravassard P, Giros B, Gaspar P, El Mestikawy S. Localization of VGLUT3, the vesicular glutamate transporter type 3, in the rat brain. Neuroscience. 123: 983-1002. PMID 14751290 DOI: 10.1016/J.Neuroscience.2003.10.039  0.758
2004 Roubert C, Spielewoy C, Soubrié P, Hamon M, Giros B, Betancur C. Altered neurotensin mrna expression in mice lacking the dopamine transporter. Neuroscience. 123: 537-46. PMID 14698760 DOI: 10.1016/J.Neuroscience.2003.08.022  0.823
2004 El Mestikawy S, Kashani A, Gras C, Gilchrist J, Bournaud M, Giros B. S.08.03 Heterogeneity of glutamatergic neurons inthe central nervous systems revealed by the distribution of vesicular glutamate transporter subtypes European Neuropsychopharmacology. 14: S128-S129. DOI: 10.1016/S0924-977X(04)80030-0  0.359
2003 Crozatier C, Guerriero RM, Mathieu F, Giros B, Nosten-Bertrand M, Kosofsky BE. Altered cocaine-induced behavioral sensitization in adult mice exposed to cocaine in utero. Brain Research. Developmental Brain Research. 147: 97-105. PMID 14741755 DOI: 10.1016/J.Devbrainres.2003.10.006  0.304
2003 Agulhon C, Rostaing P, Ravassard P, Sagné C, Triller A, Giros B. Lysosomal amino acid transporter LYAAT-1 in the rat central nervous system: an in situ hybridization and immunohistochemical study. The Journal of Comparative Neurology. 462: 71-89. PMID 12761825 DOI: 10.1002/Cne.10712  0.755
2003 Giros B, Morice E, Nosten-Bertrand M. S.20.02 Effects of psychostimulants in the absence of dopamine transporter European Neuropsychopharmacology. 13: S149-S150. DOI: 10.1016/S0924-977X(03)91677-4  0.434
2002 Gras C, Herzog E, Bellenchi GC, Bernard V, Ravassard P, Pohl M, Gasnier B, Giros B, El Mestikawy S. A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5442-51. PMID 12097496  0.753
2002 Jamain S, Betancur C, Quach H, Philippe A, Fellous M, Giros B, Gillberg C, Leboyer M, Bourgeron T. Linkage and association of the glutamate receptor 6 gene with autism. Molecular Psychiatry. 7: 302-10. PMID 11920157 DOI: 10.1038/Sj.Mp.4000979  0.313
2002 Betancur C, Corbex M, Spielewoy C, Philippe A, Laplanche JL, Launay JM, Gillberg C, Mouren-Siméoni MC, Hamon M, Giros B, Nosten-Bertrand M, Leboyer M. Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder. Molecular Psychiatry. 7: 67-71. PMID 11803447 DOI: 10.1038/Sj/Mp/4000923  0.779
2002 Gras C, Herzog E, Bellenchi GC, Bernard V, Ravassard P, Pohl M, Gasnier B, Giros B, Mestikawy SE. A Third Vesicular Glutamate Transporter Expressed by Cholinergic and Serotoninergic Neurons The Journal of Neuroscience. 22: 5442-5451. DOI: 10.1523/Jneurosci.22-13-05442.2002  0.442
2001 Spielewoy C, Biala G, Roubert C, Hamon M, Betancur C, Giros B. Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter. Psychopharmacology. 159: 2-9. PMID 11797063 DOI: 10.1007/S002130100901  0.822
2001 Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Molecular Biology of the Cell. 12: 3797-807. PMID 11739781 DOI: 10.1091/Mbc.12.12.3797  0.526
2001 Herzog E, Bellenchi GC, Gras C, Bernard V, Ravassard P, Bedet C, Gasnier B, Giros B, El Mestikawy S. The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC181. PMID 11698619  0.748
2001 Roubert C, Sagné C, Kapsimali M, Vernier P, Bourrat F, Giros B. A Na(+)/Cl(-)-dependent transporter for catecholamines, identified as a norepinephrine transporter, is expressed in the brain of the teleost fish medaka (Oryzias latipes). Molecular Pharmacology. 60: 462-73. PMID 11502876  0.764
2001 Sagné C, Agulhon C, Ravassard P, Darmon M, Hamon M, El Mestikawy S, Gasnier B, Giros B. Identification and characterization of a lysosomal transporter for small neutral amino acids. Proceedings of the National Academy of Sciences of the United States of America. 98: 7206-11. PMID 11390972 DOI: 10.1073/Pnas.121183498  0.793
2001 Syringas M, Janin F, Giros B, Costentin J, Bonnet JJ. Involvement of the NH2 terminal domain of catecholamine transporters in the Na(2+) and Cl(-)-dependence of a [3H]-dopamine uptake. British Journal of Pharmacology. 133: 387-94. PMID 11375255 DOI: 10.1038/Sj.Bjp.0704097  0.591
2001 Carboni E, Spielewoy C, Vacca C, Nosten-Bertrand M, Giros B, Di Chiara G. Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC141: 1-4. PMID 11312315 DOI: 10.1523/Jneurosci.21-09-J0001.2001  0.83
2001 Roubert C, Cox PJ, Bruss M, Hamon M, Bönisch H, Giros B. Determination of residues in the norepinephrine transporter that are critical for tricyclic antidepressant affinity. The Journal of Biological Chemistry. 276: 8254-60. PMID 11092898 DOI: 10.1074/Jbc.M009798200  0.75
2001 Herzog E, Bellenchi GC, Gras C, Bernard V, Ravassard P, Bedet C, Gasnier B, Giros B, Mestikawy SE. The Existence of a Second Vesicular Glutamate Transporter Specifies Subpopulations of Glutamatergic Neurons The Journal of Neuroscience. 21. DOI: 10.1523/Jneurosci.21-22-J0001.2001  0.427
2000 Spielewoy C, Roubert C, Hamon M, Nosten-Bertrand M, Betancur C, Giros B. Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice. Behavioural Pharmacology. 11: 279-90. PMID 11103882 DOI: 10.1097/00008877-200006000-00011  0.816
2000 Syringas M, Janin F, Mezghanni S, Giros B, Costentin J, Bonnet JJ. Structural domains of chimeric dopamine-noradrenaline human transporters involved in the Na(+)- and Cl(-)-dependence of dopamine transport. Molecular Pharmacology. 58: 1404-11. PMID 11093780 DOI: 10.1124/Mol.58.6.1404  0.602
2000 Tseng KY, Roubert C, Do L, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gershanik OS, Murer MG, Giros B, Raisman-Vozari R. Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice. Brain Research. Molecular Brain Research. 80: 1-6. PMID 11039723 DOI: 10.1016/S0169-328X(00)00107-8  0.791
2000 Spielewoy C, Gonon F, Roubert C, Fauchey V, Jaber M, Caron MG, Roques BP, Hamon M, Betancur C, Maldonado R, Giros B. Increased rewarding properties of morphine in dopamine-transporter knockout mice. The European Journal of Neuroscience. 12: 1827-37. PMID 10792459 DOI: 10.1046/J.1460-9568.2000.00063.X  0.812
2000 Masson J, Gaspar P, Aïdouni Z, Ezan P, Giros B, Hamon M, El Mestikawy S. Ontogeny of Rxt1, a vesicular "orphan" Na(+)/Cl(-)-dependent transporter, in the rat. Neuroscience. 96: 627-37. PMID 10717444 DOI: 10.1016/S0306-4522(99)00570-9  0.752
2000 Dumartin B, Jaber M, Gonon F, Caron MG, Giros B, Bloch B. Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 1879-84. PMID 10677550 DOI: 10.1073/Pnas.97.4.1879  0.613
1999 Bönisch H, Runkel F, Roubert C, Giros B, Brüss M. The human desipramine-sensitive noradrenaline transporter and the importance of defined amino acids for its function. Journal of Autonomic Pharmacology. 19: 327-33. PMID 10961738 DOI: 10.1111/J.1365-2680.1999.Tb00005.X  0.736
1999 Jaber M, Dumartin B, Sagné C, Haycock JW, Roubert C, Giros B, Bloch B, Caron MG. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. The European Journal of Neuroscience. 11: 3499-511. PMID 10564358 DOI: 10.1046/J.1460-9568.1999.00764.X  0.805
1999 Masson J, Cervera P, Côté S, Morisette J, Aïdouni Z, Giros B, Hamon M, Falardeau P, Mestikawy SE. Characterization and distribution of Hxt1, a Na(+)/Cl(-)-dependent orphan transporter, in the human brain. Journal of Neuroscience Research. 56: 146-59. PMID 10494103 DOI: 10.1002/(Sici)1097-4547(19990415)56:2<146::Aid-Jnr4>3.0.Co;2-#  0.537
1999 Masson J, Riad M, Chaudhry F, Darmon M, Aïdouni Z, Conrath M, Giros B, Hamon M, Storm-Mathisen J, Descarries L, El Mestikawy S. Unexpected localization of the Na+/Cl--dependent-like orphan transporter, Rxt1, on synaptic vesicles in the rat central nervous system. The European Journal of Neuroscience. 11: 1349-61. PMID 10103130 DOI: 10.1046/J.1460-9568.1999.00540.X  0.8
1998 Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG. Cocaine self-administration in dopamine-transporter knockout mice. Nature Neuroscience. 1: 132-7. PMID 10195128 DOI: 10.1038/381  0.715
1998 Jaber M, Bloch B, Caron MG, Giros B. [Behavioral, cellular and molecular consequences of the dopamine transporter gene inactivation]. Comptes Rendus Des Sã©Ances De La Sociã©Tã© De Biologie Et De Ses Filiales. 192: 1127-37. PMID 10101608  0.387
1998 Martres MP, Demeneix B, Hanoun N, Hamon M, Giros B. Up- and down-expression of the dopamine transporter by plasmid DNA transfer in the rat brain. The European Journal of Neuroscience. 10: 3607-16. PMID 9875340 DOI: 10.1046/J.1460-9568.1998.00366.X  0.58
1998 Cases O, Lebrand C, Giros B, Vitalis T, De Maeyer E, Caron MG, Price DJ, Gaspar P, Seif I. Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6914-27. PMID 9712661 DOI: 10.1523/Jneurosci.18-17-06914.1998  0.525
1998 Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. The Journal of Biological Chemistry. 273: 18180-4. PMID 9660778 DOI: 10.1074/Jbc.273.29.18180  0.624
1998 Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 4029-34. PMID 9520487 DOI: 10.1073/Pnas.95.7.4029  0.687
1998 Fumagalli F, Jones S, Bossé R, Jaber M, Giros B, Missale C, Wightman RM, Caron MG. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. Advances in Pharmacology (San Diego, Calif.). 42: 179-82. PMID 9327873 DOI: 10.1016/S1054-3589(08)60722-X  0.629
1998 Rocha B, Fumagalli F, Gainetdinov R, Jones S, Ator R, Giros B, Miller G, Caron M. Erratum: Cocaine self-administration in dopamine-transporter knockout mice Nature Neuroscience. 1: 330-330. DOI: 10.1038/1152  0.702
1998 Spielewoy C, Roubert C, Hamon M, Giros B. Implication of transgenic models for mental disorders: Study of the dopamine neurotransmission system European Neuropsychopharmacology. 8: S119. DOI: 10.1016/S0924-977X(98)80105-3  0.791
1997 Zhang J, Ferguson SS, Barak LS, Aber MJ, Giros B, Lefkowitz RJ, Caron MG. Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization. Receptors & Channels. 5: 193-9. PMID 9606723  0.628
1997 Sagné C, El Mestikawy S, Isambert MF, Hamon M, Henry JP, Giros B, Gasnier B. Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases. Febs Letters. 417: 177-83. PMID 9395291 DOI: 10.1016/S0014-5793(97)01279-9  0.766
1997 Jaber M, Jones S, Giros B, Caron MG. The dopamine transporter: a crucial component regulating dopamine transmission. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 629-33. PMID 9380041 DOI: 10.1002/Mds.870120502  0.695
1997 Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0  0.577
1997 Aubert I, Brana C, Pellevoisin C, Giros B, Caille I, Carles D, Vital C, Bloch B. Molecular anatomy of the development of the human substantia nigra. The Journal of Comparative Neurology. 379: 72-87. PMID 9057113 DOI: 10.1002/(Sici)1096-9861(19970303)379:1<72::Aid-Cne5>3.0.Co;2-F  0.441
1996 Masson J, Pohl M, Aïdouni Z, Giros B, Hamon M, el Mestikawy S. The two orphan Na+/Cl(-)-dependent transporters Rxt1 and V-7-3-2 have an overlapping expression pattern in the rat central nervous system. Receptors & Channels. 4: 227-42. PMID 9065971  0.725
1996 Jaber M, Koch WJ, Rockman H, Smith B, Bond RA, Sulik KK, Ross J, Lefkowitz RJ, Caron MG, Giros B. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proceedings of the National Academy of Sciences of the United States of America. 93: 12974-9. PMID 8917529 DOI: 10.1073/Pnas.93.23.12974  0.61
1996 Pifl C, Hornykiewicz O, Giros B, Caron MG. Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 277: 1437-43. PMID 8667208  0.681
1996 Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379: 606-12. PMID 8628395 DOI: 10.1038/379606A0  0.697
1996 Pifl C, Giros B, Caron MG. The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse. Advances in Neurology. 69: 235-8. PMID 8615133  0.648
1995 Masson J, Langlois X, Lanfumey L, Gérard C, Aïdouni Z, Giros B, Hamon M, el Mestikawy S. Immunolabeling of the Na+/Cl(-)-dependent "orphan" transporter Rxt1 in the rat central nervous system. Journal of Neuroscience Research. 42: 423-32. PMID 8583511 DOI: 10.1002/Jnr.490420317  0.764
1994 el Mestikawy S, Giros B, Pohl M, Hamon M, Kingsmore SF, Seldin MF, Caron MG. Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain. Journal of Neurochemistry. 62: 445-55. PMID 8294906 DOI: 10.1046/J.1471-4159.1994.62020445.X  0.812
1994 Giros B, Wang YM, Suter S, McLeskey SB, Pifl C, Caron MG. Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters. The Journal of Biological Chemistry. 269: 15985-8. PMID 8206893  0.651
1994 Li T, Yang L, Wiese C, Xu CT, Zeng Z, Giros B, Caron MG, Moises HW, Liu X. No association between alleles or genotypes at the dopamine transporter gene and schizophrenia. Psychiatry Research. 52: 17-23. PMID 8047618 DOI: 10.1016/0165-1781(94)90116-3  0.334
1994 Kingsmore SF, Giros B, Suh D, Bieniarz M, Caron MG, Seldin MF. Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Nature Genetics. 7: 136-41. PMID 7920630 DOI: 10.1038/Ng0694-136  0.484
1994 Sabaté O, Campion D, d'Amato T, Martres MP, Sokoloff P, Giros B, Leboyer M, Jay M, Guedj F, Thibaut F. Failure to find evidence for linkage or association between the dopamine D3 receptor gene and schizophrenia. The American Journal of Psychiatry. 151: 107-11. PMID 7903510 DOI: 10.1176/Ajp.151.1.107  0.31
1993 Giros B, Caron MG. Molecular characterization of the dopamine transporter. Trends in Pharmacological Sciences. 14: 43-9. PMID 8480373 DOI: 10.1016/0165-6147(93)90029-J  0.593
1993 Pifl C, Giros B, Caron MG. Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4246-53. PMID 8410185 DOI: 10.1523/Jneurosci.13-10-04246.1993  0.737
1993 Byerley W, Coon H, Hoff M, Holik J, Waldo M, Freedman R, Caron MG, Giros B. Human dopamine transporter gene not linked to schizophrenia in multigenerational pedigrees. Human Heredity. 43: 319-22. PMID 8406521 DOI: 10.1159/000154151  0.55
1993 Giros B, Sokoloff P, Martres MP, Lannfelt L, Andrieux M, Besançon R, Pilon C, Bouthenet ML, Souil E, Schwartz JC. The third dopamine receptor (D3): new perspectives in therapeutics. Psychopharmacology Series. 10: 82-93. PMID 8103228 DOI: 10.1007/978-3-642-78010-3_8  0.531
1993 Byerley W, Hoff M, Holik J, Caron MG, Giros B. VNTR polymorphism for the human dopamine transporter gene (DAT1). Human Molecular Genetics. 2: 335. PMID 8098980 DOI: 10.1093/Hmg/2.3.335  0.557
1992 Sokoloff P, Giros B, Martres MP, Andrieux M, Besancon R, Pilon C, Bouthenet ML, Souil E, Schwartz JC. Localization and function of the D3 dopamine receptor. Arzneimittel-Forschung. 42: 224-30. PMID 1586393  0.442
1992 Lévesque D, Diaz J, Pilon C, Martres MP, Giros B, Souil E, Schott D, Morgat JL, Schwartz JC, Sokoloff P. Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin. Proceedings of the National Academy of Sciences of the United States of America. 89: 8155-9. PMID 1518841 DOI: 10.1073/Pnas.89.17.8155  0.516
1992 Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG. Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Molecular Pharmacology. 42: 383-90. PMID 1406597  0.762
1992 Sokoloff P, Martres MP, Giros B, Bouthenet ML, Schwartz JC. Heterogeneity and regulation of central dopamine receptor subtypes studied by cDNA cloning methodology. Neurochemistry International. 20: 27S-32S. PMID 1365440 DOI: 10.1016/0197-0186(92)90207-8  0.553
1992 Martres MP, Sokoloff P, Giros B, Bouthenet ML, Pilon C, Lannfelt L, Schwartz JC. [Dopaminergic receptors, multiple targets for neuroleptics]. Annales Mã©Dico-Psychologiques. 150: 119-23. PMID 1364189  0.396
1992 Sokoloff P, Andrieux M, Besançon R, Pilon C, Martres MP, Giros B, Schwartz JC. Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor. European Journal of Pharmacology. 225: 331-7. PMID 1354163 DOI: 10.1016/0922-4106(92)90107-7  0.508
1992 Sokoloff P, Martres MP, Giros B, Bouthenet ML, Schwartz JC. The third dopamine receptor (D3) as a novel target for antipsychotics. Biochemical Pharmacology. 43: 659-66. PMID 1347215 DOI: 10.1016/0006-2952(92)90227-A  0.535
1992 Martres MP, Sokoloff P, Giros B, Schwartz JC. Effects of dopaminergic transmission interruption on the D2 receptor isoforms in various cerebral tissues. Journal of Neurochemistry. 58: 673-9. PMID 1309568 DOI: 10.1111/J.1471-4159.1992.Tb09770.X  0.546
1992 Lannfelt L, Sokoloff P, Martres M, Pilon C, Giros B, Jönsson E, Sedvall G, Schwartz J. Amino acid substitution in the dopamine D3 receptor as a useful polymorphism for investigating psychiatric disorders Psychiatric Genetics. 2: 249-256. DOI: 10.1097/00041444-199210000-00003  0.301
1992 Schwartz JC, Giros B, Martres MP, Sokoloff P. The dopamine receptor family: molecular biology and pharmacology Seminars in Neuroscience. 4: 99-108. DOI: 10.1016/1044-5765(92)90008-P  0.523
1992 Giros B, El Mestikawy S, Godinot N, Yang-Feng T, Caron MG. Molecular cloning, pharmacological characterization and genetic studies of the human dopamine transporter European Neuropsychopharmacology. 2: 268-269. DOI: 10.1016/0924-977X(92)90103-F  0.783
1991 Giros B, Martres MP, Pilon C, Sokoloff P, Schwartz JC. Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing. Biochemical and Biophysical Research Communications. 176: 1584-92. PMID 2039532 DOI: 10.1016/0006-291X(91)90469-N  0.533
1991 Le Coniat M, Sokoloff P, Hillion J, Martres MP, Giros B, Pilon C, Schwartz JC, Berger R. Chromosomal localization of the human D3 dopamine receptor gene. Human Genetics. 87: 618-20. PMID 1916765 DOI: 10.1007/Bf00209024  0.492
1991 Piomelli D, Pilon C, Giros B, Sokoloff P, Martres MP, Schwartz JC. Dopamine activation of the arachidonic acid cascade as a basis for D1/D2 receptor synergism. Nature. 353: 164-7. PMID 1909771 DOI: 10.1038/353164a0  0.472
1991 Bouthenet ML, Souil E, Martres MP, Sokoloff P, Giros B, Schwartz JC. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. Brain Research. 564: 203-19. PMID 1839781 DOI: 10.1016/0006-8993(91)91456-B  0.517
1991 Giros B, el Mestikawy S, Bertrand L, Caron MG. Cloning and functional characterization of a cocaine-sensitive dopamine transporter. Febs Letters. 295: 149-54. PMID 1765147 DOI: 10.1016/0014-5793(91)81406-X  0.806
1991 Schwartz JC, Sokoloff P, Giros B, Martres MP, Andrieux M, Besançon R, Bouthenet ML. The dopamine D3 receptor as a novel target for antipsychotics European Neuropsychopharmacology. 1: 197-199. DOI: 10.1016/0924-977X(91)90482-A  0.385
1990 Llorens-Cortes C, Giros B, Schwartz JC. A novel potential metallopeptidase derived from the enkephalinase gene by alternative splicing. Journal of Neurochemistry. 55: 2146-8. PMID 2230815 DOI: 10.1111/J.1471-4159.1990.Tb05810.X  0.456
1990 Llorens-Cortes C, Van Amsterdam JG, Giros B, Quach TT, Schwartz JC. Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels. Brain Research. Molecular Brain Research. 8: 227-33. PMID 2170800 DOI: 10.1016/0169-328X(90)90021-5  0.507
1990 Llorens-Cortes C, Giros B, Quach TT, Schwartz JC. Adaptative changes in two indices of enkephalin neuron activity in mouse striatum following GABAergic stimulation. Progress in Clinical and Biological Research. 328: 203-6. PMID 2154779  0.41
1990 Giros B, Martres MP, Sokoloff P, Schwartz JC. [Gene cloning of human dopaminergic D3 receptor and identification of its chromosome]. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 311: 501-8. PMID 2129115  0.394
1990 Sokoloff P, Giros B, Martres MP, Bouthenet ML, Schwartz JC. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature. 347: 146-51. PMID 1975644 DOI: 10.1038/347146A0  0.524
1990 Sokoloff P, Giros B, Martres M, Schwartz J, Bouthenet M. Le troisième récepteur de la dopamine. Une nouvelle cible d'action des neuroleptiques MéDecine/Sciences. 6: 800. DOI: 10.4267/10608/4238  0.317
1990 Giros B, Sokoloff P, Martres MP, Schwartz JC. Two D2 dopamine receptor isoforms generated via alternative mRNA splicing: regional distribution and effects of haloperidol treatments European Journal of Pharmacology. 183: 1619. DOI: 10.1016/0014-2999(90)91906-R  0.38
1989 Llorens-Cortes C, Martres MP, Van Amsterdam Y, Giros B, Gros C, Pollard H, Schwartz JC. [Dopamine and enkephalins. Effects of dopaminergic agents on the levels of striatal tyrosyl-glycyl-glycine]. L'Encã©Phale. 15: 105-9. PMID 2743934  0.475
1989 Malfroy B, Kado-Fong H, Gros C, Giros B, Schwartz JC, Hellmiss R. Molecular cloning and amino acid sequence of rat kidney aminopeptidase M: a member of a super family of zinc-metallohydrolases. Biochemical and Biophysical Research Communications. 161: 236-41. PMID 2567164 DOI: 10.1016/0006-291X(89)91586-6  0.426
1989 Giros B, Sokoloff P, Martres MP, Riou JF, Emorine LJ, Schwartz JC. Alternative splicing directs the expression of two D2 dopamine receptor isoforms. Nature. 342: 923-6. PMID 2531847 DOI: 10.1038/342923A0  0.522
1988 Gros C, Giros B, Schwartz JC, Vlaiculescu A, Costentin J, Lecomte JM. Potent inhibition of cerebral aminopeptidases by carbaphethiol, a parenterally active compound. Neuropeptides. 12: 111-8. PMID 3241626 DOI: 10.1016/0143-4179(88)90040-6  0.44
1987 Giros B, Gros C, Schwartz JC, Danvy D, Plaquevent JC, Duhamel L, Duhamel P, Vlaiculescu A, Costentin J, Lecomte JM. Enantiomers of thiorphan and acetorphan: correlation between enkephalinase inhibition, protection of endogenous enkephalins and behavioral effects. The Journal of Pharmacology and Experimental Therapeutics. 243: 666-73. PMID 3479550  0.388
1987 Michael-Titus A, Preterre P, Giros B, Costentin J. Role of endogenous enkephalins in locomotion evidenced by acetorphan, an "enkephalinase" inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 243: 1062-6. PMID 3121843  0.314
1987 Giros B, Gros C, Llorens-Cortes C, Schwartz JC. [Opioid peptides: metabolism and receptors]. Gastroentã©Rologie Clinique Et Biologique. 11: 7B-13B. PMID 3038654  0.317
1987 Giros B, Schwartz JC. [Opioid peptides and their receptors]. La Revue Du Praticien. 37: 1695-8, 1701-2. PMID 3035700  0.319
1987 Schwartz JC, Giros B, Gros C, Llorens-Cortes C, Arrang JM, Garbarg M, Pollard H. Novel agents affecting enkephalinergic and histaminergic transmissions in brain. Cephalalgia : An International Journal of Headache. 7: 32-5. PMID 2894899 DOI: 10.1177/03331024870070S610  0.437
1986 Schwartz JC, de la Baume S, Bouthenet ML, Giros B, Gros C, Llorens-Cortes C, Pollard H, Sales N, Solhonne B, Costentin J. [Neuropeptidases responsible for the inactivation of enkephalins and the pharmacology of their inhibitors]. Journal De Pharmacologie. 17: 104-22. PMID 3546953  0.326
1986 Giros B, Llorens-Cortes C, Gros C, Schwartz JC. The endogenous tripeptide Tyr-Gly-Gly as a possible metabolite of opioid peptides in rat brain: identification, regional distribution, effects of lesions and formation in depolarized slices. Peptides. 7: 669-77. PMID 3532054 DOI: 10.1016/0196-9781(86)90043-4  0.481
1986 Giros B, Llorens-Cortes C, Gros C, Schwartz JC. The endogenous tripeptide Tyr-Gly-Gly as an extracellular metabolite of enkephalins in rat brain: origin and metabolism. Nida Research Monograph. 75: 271-4. PMID 3123944  0.411
1986 Gros C, Solhonne B, Giros B, Pollard H, Salès N, Schwartz JC, Ronco P, Verroust P. Immunohistochemical and subcellular studies of aminopeptidase M localization in rat brain: microvessels and synaptic membranes. Nida Research Monograph. 75: 303-6. PMID 2893270  0.378
1986 Giros B, Gros C, Solhonne B, Schwartz JC. Characterization of aminopeptidases responsible for inactivating endogenous (Met5)enkephalin in brain slices using peptidase inhibitors and anti-aminopeptidase M antibodies. Molecular Pharmacology. 29: 281-7. PMID 2869404  0.356
1985 Gros C, Giros B, Schwartz JC. Purification of membrane-bound aminopeptidase from rat brain: identification of aminopeptidase M. Neuropeptides. 5: 485-8. PMID 2860607 DOI: 10.1016/0143-4179(85)90060-5  0.434
1985 Gros C, Giros B, Llorens C, Malfroy B, Pollard H, Pachot I, Schwartz JC, Mazie JC. Enkephalin metabolism and its inhibition. Biochemical Society Transactions. 13: 47-50. PMID 2860040 DOI: 10.1042/Bst0130047  0.394
1985 Gros C, Giros B, Schwartz JC. Identification of aminopeptidase M as an enkephalin-inactivating enzyme in rat cerebral membranes. Biochemistry. 24: 2179-85. PMID 2859885 DOI: 10.1021/Bi00330A011  0.452
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