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Aakanksha Khandelwal, Ph.D. - Publications

Affiliations: 
2007 University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Pharmacology, Oncology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Godbole AM, Ramalingam S, Ramamurthy VP, Khandelwal A, Bruno RD, Upreti VV, Gediya LK, Purushottamachar P, Mbatia HW, Addya S, Ambulos N, Njar VC. VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats. European Journal of Pharmacology. 734: 98-104. PMID 24726842 DOI: 10.1016/J.Ejphar.2014.04.004  0.674
2008 Vasaitis T, Belosay A, Schayowitz A, Khandelwal A, Chopra P, Gediya LK, Guo Z, Fang HB, Njar VC, Brodie AM. Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer. Molecular Cancer Therapeutics. 7: 2348-57. PMID 18723482 DOI: 10.1158/1535-7163.MCT-08-0230  0.677
2008 Gediya LK, Khandelwal A, Patel J, Belosay A, Sabnis G, Mehta J, Purushottamachar P, Njar VC. Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro. Journal of Medicinal Chemistry. 51: 3895-904. PMID 18543902 DOI: 10.1021/Jm8001839  0.749
2008 Khandelwal A, Gediya L, Njar V. MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours. British Journal of Cancer. 98: 1234-43. PMID 18349838 DOI: 10.1038/Sj.Bjc.6604295  0.702
2008 Purushottamachar P, Khandelwal A, Vasaitis TS, Bruno RD, Gediya LK, Njar VC. Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent. Bioorganic & Medicinal Chemistry. 16: 3519-29. PMID 18316193 DOI: 10.1016/J.Bmc.2008.02.031  0.762
2008 Gediya LK, Belosay A, Khandelwal A, Purushottamachar P, Njar VC. Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Bioorganic & Medicinal Chemistry. 16: 3352-60. PMID 18166465 DOI: 10.1016/J.Bmc.2007.12.007  0.721
2008 Gediya L, Purushottamachar P, Khandelwal A, Mehta J, Godbole A, Njar V. 27 INVITED Novel atypical retinoic acid metabolism blocking agents (RAMBAs)/ CYP26 inhibitors for breast cancer therapy European Journal of Cancer Supplements. 6: 12. DOI: 10.1016/S1359-6349(08)71959-1  0.767
2007 Patel JB, Mehta J, Belosay A, Sabnis G, Khandelwal A, Brodie AM, Soprano DR, Njar VC. Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth. British Journal of Cancer. 96: 1204-15. PMID 17387344 DOI: 10.1038/Sj.Bjc.6603705  0.773
2007 Purushottamachar P, Khandelwal A, Chopra P, Maheshwari N, Gediya LK, Vasaitis TS, Bruno RD, Clement OO, Njar VC. First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents. Bioorganic & Medicinal Chemistry. 15: 3413-21. PMID 17383188 DOI: 10.1016/J.Bmc.2007.03.019  0.752
2007 Patel JB, Khandelwal A, Chopra P, Handratta VD, Njar VC. Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents. Cancer Chemotherapy and Pharmacology. 60: 899-905. PMID 17345084 DOI: 10.1007/S00280-007-0438-3  0.784
2006 Njar VC, Gediya L, Purushottamachar P, Chopra P, Vasaitis TS, Khandelwal A, Mehta J, Huynh C, Belosay A, Patel J. Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases. Bioorganic & Medicinal Chemistry. 14: 4323-40. PMID 16530416 DOI: 10.1016/J.Bmc.2006.02.041  0.732
2006 Njar VCO, Gediya L, Purushottamachar P, Chopra P, Vasaitis TS, Khandelwal A, Mehta J, Huynh C, Belosay A, Patel J. Retinoic Acid Metabolism Blocking Agents (RAMBAs) for Treatment of Cancer and Dermatological Diseases Cheminform. 37. DOI: 10.1002/CHIN.200637236  0.623
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