Meryl H. Karol - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Toxicology, Public Health, Occupational Health and Safety

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Mitchell CS, Zhang JJ, Sigsgaard T, Jantunen M, Lioy PJ, Samson R, Karol MH. Current state of the science: health effects and indoor environmental quality. Environmental Health Perspectives. 115: 958-64. PMID 17589607 DOI: 10.1289/Ehp.8987  0.325
2005 Brownawell AM, Berent S, Brent RL, Bruckner JV, Doull J, Gershwin EM, Hood RD, Matanoski GM, Rubin R, Weiss B, Karol MH. The potential adverse health effects of dental amalgam. Toxicological Reviews. 24: 1-10. PMID 16042501 DOI: 10.2165/00139709-200524010-00001  0.308
2002 Karol MH. Respiratory allergy: what are the uncertainties? Toxicology. 181: 305-10. PMID 12505330 DOI: 10.1016/S0300-483X(02)00298-6  0.384
2002 Matheson JM, Lemus R, Lange RW, Karol MH, Luster MI. Role of tumor necrosis factor in toluene diisocyanate asthma American Journal of Respiratory Cell and Molecular Biology. 27: 396-405. PMID 12356572 DOI: 10.1165/Rcmb.4614  0.361
2002 Redlich CA, Karol MH. Diisocyanate asthma: clinical aspects and immunopathogenesis. International Immunopharmacology. 2: 213-24. PMID 11811926 DOI: 10.1016/S1567-5769(01)00174-6  0.392
2002 Luster MI, Karol MH. Preface to Occupational Immunology International Immunopharmacology. 2: 161-162. DOI: 10.1016/S1567-5769(01)00168-0  0.321
2001 Lemus R, Lukinskeine L, Bier ME, Wisnewski AV, Redlich CA, Karol MH. Development of immunoassays for biomonitoring of hexamethylene diisocyanate exposure. Environmental Health Perspectives. 109: 1103-1108. PMID 11712993 DOI: 10.1289/Ehp.011091103  0.405
2001 Matheson JM, Lange RW, Lemus R, Karol MH, Luster MI. Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI) Clinical and Experimental Allergy. 31: 1067-1076. PMID 11467998 DOI: 10.1046/J.1365-2222.2001.01125.X  0.407
2001 Ebino K, Ueda H, Kawakatsu H, Shutoh Y, Kosaka T, Nagayoshi E, Lemus R, Karol MH. Isolated airway exposure to toluene diisocyanate results in skin sensitization. Toxicology Letters. 121: 79-85. PMID 11312040 DOI: 10.1016/S0378-4274(01)00325-3  0.409
2001 Lantz RC, Lemus R, Lange RW, Karol MH. Rapid reduction of intracellular glutathione in human bronchial epithelial cells exposed to occupational levels of Toluene diisocyanate Toxicological Sciences. 60: 348-355. PMID 11248147 DOI: 10.1093/Toxsci/60.2.348  0.379
2000 Wisnewski AV, Srivastava R, Herick C, Xu L, Lemus R, Cain H, Magoski NM, Karol MH, Bottomly K, Redlich CA. Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo. American Journal of Respiratory and Critical Care Medicine. 162: 2330-6. PMID 11112159 DOI: 10.1164/Ajrccm.162.6.2002086  0.359
2000 Smith JS, Macina OT, Sussman NB, Luster MI, Karol MH. A robust structure-activity relationship (SAR) model for esters that cause skin irritation in humans Toxicological Sciences. 55: 215-222. PMID 10788576 DOI: 10.1093/Toxsci/55.1.215  0.303
2000 Smith JS, Macina OT, Sussman NB, Karol MH, Maibach HI. Experimental validation of a structure-activity relationship model of skin irritation by esters Quantitative Structure-Activity Relationships. 19: 467-474. DOI: 10.1002/1521-3838(200012)19:5<467::Aid-Qsar467>3.0.Co;2-#  0.308
1999 Lange RW, Day BW, Lemus R, Tyurin VA, Kagan VE, Karol MH. Intracellular S-glutathionyl adducts in murine lung and human bronchoepithelial cells after exposure to diisocyanatotoluene. Chemical Research in Toxicology. 12: 931-6. PMID 10525268 DOI: 10.1021/Tx990045H  0.369
1999 Lange RW, Lantz RC, Stolz DB, Watkins SC, Sundareshan P, Lemus R, Karol MH. Toluene diisocyanate colocalizes with tubulin on cilia of differentiated human airway epithelial cells Toxicological Sciences. 50: 64-71. PMID 10445754 DOI: 10.1093/Toxsci/50.1.64  0.399
1999 Rosenkranz HS, Klopman G, Zhang YP, Graham C, Karol MH. Relationship between allergic contact dermatitis and electrophilicity. Environmental Health Perspectives. 107: 129-32. PMID 9924008 DOI: 10.1289/Ehp.99107129  0.314
1998 Jones M, Graham C, Taylor AN, Sarlo K, Hoyle V, Karol MH. Immunologic cross-reactivity between respiratory chemical sensitizers: reactive dyes and cyanuric chloride. The Journal of Allergy and Clinical Immunology. 102: 835-40. PMID 9819302 DOI: 10.1016/S0091-6749(98)70025-9  0.382
1997 Graham C, Rosenkranz HS, Karol MH. Structure-activity model of chemicals that cause human respiratory sensitization. Regulatory Toxicology and Pharmacology. 26: 296-306. PMID 9441920 DOI: 10.1006/Rtph.1997.1170  0.371
1997 Karol MH, Pittsburgh, Pennsylvania, Lantz RC. Immunohistochemical detection of toluene diisocyanate (TDI) adducts in pulmonary tissue of guinea pigs following inhalation exposure Inhalation Toxicology. 9: 63-84. DOI: 10.1080/089583797198277  0.459
1997 Zhang YP, Macina OT, Rosenkranz HS, Karol MH, Mattison DR, Klopman G. Prediction of the metabolism and toxicological profiles of gasoline oxygenates Inhalation Toxicology. 9: 237-254. DOI: 10.1080/089583797198231  0.316
1996 Karol MH, Kramarik JA. Phenyl isocyanate is a potent chemical sensitizer. Toxicology Letters. 89: 139-146. PMID 8960156 DOI: 10.1016/S0378-4274(96)03798-8  0.432
1996 Gealy R, Graham C, Sussman NB, Macina OT, Rosenkranz HS, Karol MH. Evaluating clinical case report data for SAR modeling of allergic contact dermatitis Human and Experimental Toxicology. 15: 489-493. PMID 8793531 DOI: 10.1177/096032719601500605  0.329
1996 Karol MH, Graham C, Gealy R, Macina OT, Sussman N, Rosenkranz HS. Structure-activity relationships and computer-assisted analysis of respiratory sensitization potential. Toxicology Letters. 86: 187-191. PMID 8711771 DOI: 10.1016/0378-4274(96)03689-2  0.385
1996 Shvedova AA, Satoh T, Tollerud D, Guevarra L, Karol MH. Elevated Levels of IL-6, INF-γ, And Tnf-α In Mice in Response to Cotton Dust are Modulated by Anti-Tnf-α Antiserum Experimental Lung Research. 22: 149-161. PMID 8706633 DOI: 10.3109/01902149609050844  0.335
1996 Mapp CE, Silva JRLe, Lucchini RE, Chitano P, Rado V, Saetta M, Pretolani M, Karol MH, Maestrelli P, Fabbri LM. Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate. American Journal of Respiratory and Critical Care Medicine. 154: 201-208. PMID 8680681 DOI: 10.1164/Ajrccm.154.1.8680681  0.351
1996 Kimber I, Bernstein IL, Karol MH, Robinson MK, Sarlo K, Selgrade MK. Identification of Respiratory Allergens Toxicological Sciences. 33: 1-10. DOI: 10.1093/Toxsci/33.1.1  0.402
1996 Graham C, Gealy R, Macina OT, Karol MH, Rosenkranz HS. Qsar For Allergic Contact Dermatitis Quantitative Structure-Activity Relationships. 15: 224-229. DOI: 10.1002/Qsar.19960150307  0.356
1995 Shvedova AA, Menshikova EV, Ritov VB, Kagan VE, Karol MH. Murine Pulmonary Ca2+ -Transport System Activated by Allergic Immune Response Retains Sensitivity to Oxidative Stress Experimental Lung Research. 21: 743-770. PMID 8556992 DOI: 10.3109/01902149509050840  0.356
1995 Shvedova AA, Kisin ER, Kagan VE, Karol MH. Increased lipid peroxidation and decreased antioxidants in lungs of guinea pigs following an allergic pulmonary response. Toxicology and Applied Pharmacology. 132: 72-81. PMID 7747287 DOI: 10.1006/Taap.1995.1088  0.37
1995 Satoh T, Kramarik JA, Tollerud DJ, Karol MH. A murine model for assessing the respiratory hypersensitivity potential of chemical allergens. Toxicology Letters. 78: 57-66. PMID 7604400 DOI: 10.1016/0378-4274(94)03234-X  0.437
1994 Karol M, Tollerud D, Campbell T, Fabbri L, Maestrelli P, Saetta M, Mapp C. Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge. American Journal of Respiratory and Critical Care Medicine. 149: 611-615. PMID 8118626 DOI: 10.1164/Ajrccm.149.3.8118626  0.385
1994 Ryan LK, Jin R, Boggs SS, Karol MH, Day BW. Mouse model for assessing endotoxin involvement in the lung inflammation and cytokine production resulting from inhaled organic dust Inhalation Toxicology. 6: 485-499. DOI: 10.3109/08958379409040506  0.362
1994 Selgrade MK, Zeiss CR, Karol MH, Sarlo K, Kimber I, Tepper JS, Henry MC. Workshop on Status of Test Methods for Assessing Potential of Chemicals to Induce Respiratory Allergic Reactions Inhalation Toxicology. 6: 303-319. DOI: 10.3109/08958379408995238  0.366
1993 Griffiths‐Johnson D, Jin R, Karol MH. Role of purified IgG1 in pulmonary hypersensitivity responses of the guinea pig. Journal of Toxicology and Environmental Health. 40: 117-127. PMID 8360939 DOI: 10.1080/15287399309531779  0.425
1992 Ruppel-Kerr R, Lemp JA, Karol MH. Antibody to recombinant murine tumor necrosis factor (TNF) neutralizes guinea pig TNF. Journal of Immunological Methods. 154: 179-184. PMID 1401952 DOI: 10.1016/0022-1759(92)90190-5  0.396
1991 Karol M, Jin R, Bennedsen M, Vaughan F. Production and isolation of guinea pig IgE antibody Journal of Immunological Methods. 139: 123-134. PMID 2040810 DOI: 10.1016/0022-1759(91)90359-N  0.368
1991 Griffiths-Johnson DA, Karol MH. Validation of a non-invasive technique to assess development of airway hyperreactivity in an animal model of immunologic pulmonary hypersensitivity. Toxicology. 65: 283-294. PMID 1992562 DOI: 10.1016/0300-483X(91)90087-H  0.385
1991 Ryan LK, Karol MH. Release of Tumor Necrosis Factor in Guinea Pigs upon Acute Inhalation of Cotton Dust American Journal of Respiratory Cell and Molecular Biology. 5: 93-98. PMID 1878256 DOI: 10.1165/Ajrcmb/5.1.93  0.362
1991 Karol MH. Allergic reactions to indoor air pollutants. Environmental Health Perspectives. 95: 45-51. PMID 1821377 DOI: 10.1289/Ehp.919545  0.427
1991 Griffiths-johnson DA, Ryan L, Karol MH. Development of an animal model for organic dust toxic syndrome Inhalation Toxicology. 3: 405-417. DOI: 10.3109/08958379109145298  0.406
1989 Ryan LK, Karol MH. Acute respiratory response of guinea pigs to lipopolysaccharide, lipid A, and monophosphoryl lipid A from Salmonella minnesota. The American Review of Respiratory Disease. 140: 1429-1435. PMID 2817607 DOI: 10.1164/Ajrccm/140.5.1429  0.314
1989 Thorne PS, Karol MH. Association of fever with late-onset pulmonary hypersensitivity responses in the guinea pig. Toxicology and Applied Pharmacology. 100: 247-258. PMID 2781557 DOI: 10.1016/0041-008X(89)90311-6  0.41
1989 Karol MH, Hillebrand JA, Thorne PS. Characteristics of weekly pulmonary hypersensitivity responses elicited in the guinea pig by inhalation of ovalbumin aerosols Toxicology and Applied Pharmacology. 100: 234-246. PMID 2781556 DOI: 10.1016/0041-008X(89)90310-4  0.464
1988 Olaniran NS, Karol MH. Serologic study of guinea pigs exposed for 12 months to cotton dust. Journal of Toxicology and Environmental Health. 25: 185-199. PMID 3172272 DOI: 10.1080/15287398809531200  0.417
1988 Thorne PS, Karol MH. Assessment of airway reactivity in guinea pigs: comparison of methods employing whole body plethysmography. Toxicology. 52: 141-163. PMID 3142103 DOI: 10.1016/0300-483X(88)90201-6  0.357
1988 Ryan LK, Karol MH. Production of antibody to lipopolysaccharide (LPS) after immunization with a LPS-polymyxin B-agarose immunogen. Journal of Applied Microbiology. 64: 487-495. PMID 3049507 DOI: 10.1111/J.1365-2672.1988.Tb02440.X  0.312
1988 Jin R, Karol MH. Diisocyanate antigens that detect specific antibodies in exposed workers and guinea pigs Chemical Research in Toxicology. 1: 288-293. PMID 2979745 DOI: 10.1021/Tx00005A006  0.402
1987 Thorne PS, Hillebrand JA, Lewis GR, Karol MH. Contact sensitivity by diisocyanates: potencies and cross-reactivities. Toxicology and Applied Pharmacology. 87: 155-165. PMID 3798450 DOI: 10.1016/0041-008X(87)90093-7  0.372
1987 Thorne PS, Yeske CP, Karol MH. Monitoring guinea pig core temperature by telemetry during inhalation exposures. Toxicological Sciences. 9: 398-408. PMID 3691999 DOI: 10.1016/0272-0590(87)90022-4  0.312
1987 Karol MH, Taskar S, Gangal S, Rubanoff BF, Kamat SR. The antibody response to methyl isocyanate: experimental and clinical findings Environmental Health Perspectives. 72: 169-175. PMID 3622432 DOI: 10.1289/Ehp.8772169  0.431
1987 Hillebrand JA, Thorne PS, Karol MH. Experimental sensitization to subtilisin. II. Production of specific antibodies following inhalation exposure of guinea pigs. Toxicology and Applied Pharmacology. 89: 449-456. PMID 3299874 DOI: 10.1016/0041-008X(87)90164-5  0.466
1987 Ellakkani MA, Alarie Y, Weyel D, Karol MH. Chronic pulmonary effects in guinea pigs from prolonged inhalation of cotton dust. Toxicology and Applied Pharmacology. 88: 354-369. PMID 3107166 DOI: 10.1016/0041-008X(87)90211-0  0.423
1986 Thorne PS, Hillebrand J, Magreni C, Riley EJ, Karol MH. Experimental sensitization to subtilisin : I. Production of immediate- and late-onset pulmonary reactions Toxicology and Applied Pharmacology. 86: 112-123. PMID 3532428 DOI: 10.1016/0041-008X(86)90404-7  0.445
1986 Karol MH, Dean JH. Respiratory effects of inhaled isocyanates Critical Reviews in Toxicology. 16: 349-379. PMID 3519088 DOI: 10.3109/10408448609037467  0.429
1985 Stadler JC, Karol MH. Use of dose-response data to compare the skin sensitizing abilities of dicyclohexylmethane-4,4′-diisocyanate and picryl chloride in two animal species☆ Toxicology and Applied Pharmacology. 78: 445-450. PMID 4049393 DOI: 10.1016/0041-008X(85)90251-0  0.381
1985 Ellakkani MA, Alarie YC, Weyel DA, Karol MH. Concentration-dependent respiratory response of guinea pigs to a single exposure of cotton dust Toxicology and Applied Pharmacology. 80: 357-366. PMID 4024124 DOI: 10.1016/0041-008X(85)90093-6  0.416
1985 Karol MH, Stadler J, Magreni C. Immunotoxicologic evaluation of the respiratory system: Animal models for immediate- and delayed-onset pulmonary hypersensitivity☆ Toxicological Sciences. 5: 459-472. PMID 2989053 DOI: 10.1016/0272-0590(85)90093-4  0.473
1985 Wong K, Karol MH, Alarie Y. Use of repeated co2 challenges to evaluate the pulmonary performance of guinea pigs exposed to toluene diisocyanate Journal of Toxicology and Environmental Health. 15: 137-148. PMID 2984437 DOI: 10.1080/15287398509530641  0.415
1984 Stadler J, Karol MH. Experimental delayed hypersensitivity following inhalation of dicyclohexylmethane-4,4′-diisocyanate: A concentration-response relationship☆ Toxicology and Applied Pharmacology. 74: 244-249. PMID 6740674 DOI: 10.1016/0041-008X(84)90149-2  0.457
1984 Karol MH, Hansen GA, Brown WE. Effects of inhaled hexamethylene diisocyanate (HDI) on guinea pig cholinesterases. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: 284-7. PMID 6724200 DOI: 10.1016/0272-0590(84)90130-1  0.396
1984 Brown WE, Shamoo AY, Hill BL, Karol MH. Immobilized cholinesterase to detect airborne concentrations of hexamethylene diisocyanate (HDI) Toxicology and Applied Pharmacology. 73: 105-109. PMID 6710507 DOI: 10.1016/0041-008X(84)90058-9  0.389
1984 Chang KC, Karol MH. Diphenylmethane diisocyanate (MDI)‐induced asthma: evaluation of the immunologic responses and application of an animal model of isocyanate sensitivity Clinical & Experimental Allergy. 14: 329-339. PMID 6467557 DOI: 10.1111/J.1365-2222.1984.Tb02213.X  0.401
1984 Lee HK, Alarie Y, Karol MH. Induction of formaldehyde sensitivity in guinea pigs. Toxicology and Applied Pharmacology. 75: 147-155. PMID 6464018 DOI: 10.1016/0041-008X(84)90085-1  0.475
1984 Ellakkani MA, Alarie YC, Weyel DA, Mazumdar S, Karol MH. Pulmonary reactions to inhaled cotton dust: An animal model for byssinosis☆ Toxicology and Applied Pharmacology. 74: 267-284. PMID 6429899 DOI: 10.1016/0041-008X(84)90152-2  0.424
1983 Karol MH. Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposure. Toxicology and Applied Pharmacology. 68: 229-241. PMID 6304938 DOI: 10.1016/0041-008X(83)90007-8  0.498
1983 Shapiro MA, Karol MH, Keleti G, Sykora JL, Martinez AJ. The Role of Free-Living Amoebae Occurring in Heated Effluents as Causative Agents of Human Disease Water Science and Technology. 15: 135-147. DOI: 10.2166/Wst.1983.0061  0.312
1982 Karol MH, Stadler J, Underhill D, Alarie Y. Monitoring delayed-onset pulmonary hypersensitivity in guinea pigs. Toxicology and Applied Pharmacology. 61: 277-85. PMID 7324069 DOI: 10.1016/0041-008X(81)90418-X  0.405
1982 Karol MH, Magreni C. Extensive skin sensitization with minimal antibody production in guinea pigs as a result of exposure to dicyclohexylmethane-4,4'-diisocyanate. Toxicology and Applied Pharmacology. 65: 291-301. PMID 7179285 DOI: 10.1016/0041-008X(82)90012-6  0.432
1982 Karol MH, Hauth BA. Use of Hexyl Isocyanate Antigen to Detect Antibodies to Hexamethylene Diisocyanate (HDI) in Sensitized Guinea Pigs and in a Sensitized Worker Toxicological Sciences. 2: 108-113. PMID 6821040 DOI: 10.1016/S0272-0590(82)80090-0  0.417
1982 Stadler J, Karol MH. Experimental delayed-onset pulmonary sensitivity: Identification of retest reactions in the lung Toxicology and Applied Pharmacology. 65: 323-328. PMID 6817470 DOI: 10.1016/0041-008X(82)90015-1  0.416
1982 Brown WE, Green AH, Karol MH, Alarie YC. Inhibition of cholinesterase activity by isocyanates. Toxicology and Applied Pharmacology. 63: 45-52. PMID 6280343 DOI: 10.1016/0041-008X(82)90025-4  0.33
1982 Sykora J, Karol M, Keleti G, Novak D. Amoebae as sources of hypersensitivity pneumonitis Environment International. 8: 343-347. DOI: 10.1016/0160-4120(82)90048-4  0.415
1981 Karol MH, Alarie Y. Serologic assays for antibodies to HDI and MDI Contact Dermatitis. 7: 60-61. PMID 7249635 DOI: 10.1111/J.1600-0536.1981.Tb03977.X  0.323
1981 Karol MH. Survey of industrial workers for antibodies to toluene diisocyanate. Journal of Occupational and Environmental Medicine. 23: 741-747. PMID 6275057 DOI: 10.1097/00043764-198111000-00007  0.322
1981 Karol MH, Hauth BA, Riley EJ, Magreni CM. Dermal contact with toluene diisocyanate (TDI) produces respiratory tract hypersensitivity in guinea pigs. Toxicology and Applied Pharmacology. 58: 221-230. PMID 6264649 DOI: 10.1016/0041-008X(81)90426-9  0.484
1981 Karol MH, Alarie Y. Serologic assays for antibodies to hexamethylene diisocyanate and diphenylmethane diisocyanate. Archives of Dermatology. 117: 456-456. DOI: 10.1001/Archderm.1981.01650080008015  0.417
1980 Karol MH, Dixon C, Brady M, Alarie Y. Immunologic sensitization and pulmonary hypersensitivity by repeated inhalation of aromatic isocyanates. Toxicology and Applied Pharmacology. 53: 260-270. PMID 6249000 DOI: 10.1016/0041-008X(80)90425-1  0.475
1980 Karol MH, Alarie Y. IgE antibodies in TDI workers. The Journal of Allergy and Clinical Immunology. 65: 162. PMID 6243321 DOI: 10.1016/0091-6749(80)90202-X  0.347
1980 Karol MH. Study of guinea pig and human antibodies to toluene diisocyanate. The American Review of Respiratory Disease. 122: 965. PMID 6161573 DOI: 10.1164/Arrd.1980.122.6.965  0.388
1979 Karol MH, Ioset HH, Alarie YC. Effect of coal dust inhalation on pulmonary immunologic responses. American Industrial Hygiene Association Journal. 40: 283-290. PMID 474412 DOI: 10.1080/15298667991429606  0.434
1979 Karol MH, Hauth BA, Alarie Y. Pulmonary hypersensitivity to hexyl isocyanate-ovalbumin aerosol in guinea pigs. Toxicology and Applied Pharmacology. 51: 73-80. PMID 118546 DOI: 10.1016/0041-008X(79)90009-7  0.478
1978 Karol MH, Ioset HH, Alarie YC. Tolyl-specific IgE antibodies in workers with hypersensitivity to toluene diisocyanate American Industrial Hygiene Association Journal. 39: 454-458. PMID 210646 DOI: 10.1080/0002889778507789  0.399
1977 Cypess RH, Karol MH, Zidian JL, Glickman LT, Gitlin D. Larva-specific antibodies in patients with visceral larva migrans. The Journal of Infectious Diseases. 135: 633-40. PMID 853247 DOI: 10.1093/Infdis/135.4.633  0.325
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