123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, et al. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metabolism. PMID 30827863 DOI: 10.1016/j.cmet.2019.01.023  0.48
2018 O'Driscoll CA, Gallo ME, Hoffmann EJ, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD. Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro. Plos One. 13: e0209690. PMID 30576387 DOI: 10.1371/journal.pone.0209690  0.64
2018 O'Driscoll CA, Owens LA, Hoffmann EJ, Gallo ME, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD. Ambient urban dust particulate matter reduces pathologic T cells in the CNS and severity of EAE. Environmental Research. 168: 178-192. PMID 30316103 DOI: 10.1016/j.envres.2018.09.038  0.64
2018 O'Driscoll CA, Owens LA, Gallo ME, Hoffmann EJ, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD. Differential effects of diesel exhaust particles on T cell differentiation and autoimmune disease. Particle and Fibre Toxicology. 15: 35. PMID 30143013 DOI: 10.1186/s12989-018-0271-3  0.64
2017 Seok SH, Ma ZX, Feltenberger JB, Chen H, Chen H, Scarlett C, Lin Z, Satyshur KA, Cortopassi M, Jefcoate CR, Ge Y, Tang W, Bradfield CA, Xing Y. Trace Derivatives of Kynurenine Potently Activate the Aryl Hydrocarbon Receptor (AHR). The Journal of Biological Chemistry. PMID 29279331 DOI: 10.1074/jbc.RA117.000631  0.44
2017 Shen AL, Moran SM, Glover EA, Teixeira LB, Bradfield CA. Retinal pathology in the PPCD1 mouse. Plos One. 12: e0185094. PMID 28981549 DOI: 10.1371/journal.pone.0185094  0.72
2017 Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396409 DOI: 10.1073/pnas.1617035114  0.44
2016 Díaz-Díaz CJ, Ronnekleiv-Kelly SM, Nukaya M, Geiger PG, Balbo S, Dator R, Megna BW, Carney PR, Bradfield CA, Kennedy GD. The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse. Annals of Surgery. PMID 27433903 DOI: 10.1097/SLA.0000000000001874  1
2016 Shen AL, Moran SA, Glover EA, Drinkwater NR, Swearingen RE, Teixeira LB, Bradfield CA. Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression. Plos One. 11: e0157577. PMID 27310661 DOI: 10.1371/journal.pone.0157577  1
2015 Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J. Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science (New York, N.Y.). 350: aac4250. PMID 26542580 DOI: 10.1126/science.aac4250  1
2014 Izumo M, Pejchal M, Schook AC, Lange RP, Walisser JA, Sato TR, Wang X, Bradfield CA, Takahashi JS. Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant. Elife. 3. PMID 25525750 DOI: 10.7554/eLife.04617  0.92
2014 Johnson BP, Walisser JA, Liu Y, Shen AL, McDearmon EL, Moran SM, McIntosh BE, Vollrath AL, Schook AC, Takahashi JS, Bradfield CA. Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18757-62. PMID 25512522 DOI: 10.1073/pnas.1421708111  1
2014 Liu Y, Johnson BP, Shen AL, Wallisser JA, Krentz KJ, Moran SM, Sullivan R, Glover E, Parlow AF, Drinkwater NR, Schuler LA, Bradfield CA. Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 14295-300. PMID 25225411 DOI: 10.1073/pnas.1209249111  1
2014 Sengupta S, Johnson BP, Swanson SA, Stewart R, Bradfield CA, Thomson JA. Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 236-45. PMID 24752503 DOI: 10.1093/toxsci/kfu069  1
2014 Kennedy GD, Nukaya M, Moran SM, Glover E, Weinberg S, Balbo S, Hecht SS, Pitot HC, Drinkwater NR, Bradfield CA. Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 135-43. PMID 24718703 DOI: 10.1093/toxsci/kfu065  1
2012 Paschos GK, Ibrahim S, Song WL, Kunieda T, Grant G, Reyes TM, Bradfield CA, Vaughan CH, Eiden M, Masoodi M, Griffin JL, Wang F, Lawson JA, Fitzgerald GA. Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nature Medicine. 18: 1768-77. PMID 23142819 DOI: 10.1038/nm.2979  0.4
2012 Pauly SK, Fechner JH, Zhang X, Torrealba J, Bradfield CA, Mezrich JD. The Aryl Hydrocarbon Receptor Influences Transplant Outcomes in Response to Environmental Signals. Toxicological and Environmental Chemistry. 94: 1175-1187. PMID 23002321 DOI: 10.1080/02772248.2012.688546  0.64
2012 Mezrich JD, Nguyen LP, Kennedy G, Nukaya M, Fechner JH, Zhang X, Xing Y, Bradfield CA. SU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulation. Plos One. 7: e44547. PMID 22970246 DOI: 10.1371/journal.pone.0044547  0.92
2012 Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Löhr CV, Arlt VM, Phillips DH, Williams DE, Baird WM. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicology and Applied Pharmacology. 264: 377-86. PMID 22935520 DOI: 10.1016/j.taap.2012.08.014  1
2012 Xing Y, Nukaya M, Satyshur KA, Jiang L, Stanevich V, Korkmaz EN, Burdette L, Kennedy GD, Cui Q, Bradfield CA. Identification of the Ah-receptor structural determinants for ligand preferences. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 86-97. PMID 22659362 DOI: 10.1093/toxsci/kfs194  0.44
2012 Cobleigh MA, Bradfield C, Liu Y, Mehta A, Robek MD. The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate. Journal of Virology. 86: 4253-61. PMID 22345454 DOI: 10.1128/JVI.05991-11  0.52
2012 Lee JS, Cella M, McDonald KG, Garlanda C, Kennedy GD, Nukaya M, Mantovani A, Kopan R, Bradfield CA, Newberry RD, Colonna M. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nature Immunology. 13: 144-51. PMID 22101730 DOI: 10.1038/ni.2187  0.44
2011 Chernoff N, Rogers EH, Zehr RD, Gage MI, Malarkey DE, Bradfield CA, Liu Y, Schmid JE, Jaskot RH, Richards JH, Wood CR, Rosen MB. Toxicity and recovery in the pregnant mouse after gestational exposure to the cyanobacterial toxin, cylindrospermopsin. Journal of Applied Toxicology : Jat. 31: 242-54. PMID 20936652 DOI: 10.1002/jat.1586  0.52
2010 Nukaya M, Walisser JA, Moran SM, Kennedy GD, Bradfield CA. Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 554-63. PMID 20935161 DOI: 10.1093/toxsci/kfq305  1
2010 Nukaya M, Lin BC, Glover E, Moran SM, Kennedy GD, Bradfield CA. The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes. The Journal of Biological Chemistry. 285: 35599-605. PMID 20829355 DOI: 10.1074/jbc.M110.132043  1
2010 Shen AL, O'Leary KA, Dubielzig RR, Drinkwater N, Murphy CJ, Kasper CB, Bradfield CA. The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene. Plos One. 5: e12213. PMID 20808945 DOI: 10.1371/journal.pone.0012213  1
2010 Mezrich JD, Fechner JH, Zhang X, Johnson BP, Burlingham WJ, Bradfield CA. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 3190-8. PMID 20720200 DOI: 10.4049/jimmunol.0903670  0.64
2010 Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 466: 627-31. PMID 20562852 DOI: 10.1038/nature09253  1
2010 McIntosh BE, Hogenesch JB, Bradfield CA. Mammalian Per-Arnt-Sim proteins in environmental adaptation. Annual Review of Physiology. 72: 625-45. PMID 20148691 DOI: 10.1146/annurev-physiol-021909-135922  0.76
2009 Nguyen LP, Hsu EL, Chowdhury G, Dostalek M, Guengerich FP, Bradfield CA. D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan. Chemical Research in Toxicology. 22: 1897-904. PMID 19860415 DOI: 10.1021/tx900043s  0.92
2009 Chowdhury G, Dostalek M, Hsu EL, Nguyen LP, Stec DF, Bradfield CA, Guengerich FP. Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid. Chemical Research in Toxicology. 22: 1905-12. PMID 19860413 DOI: 10.1021/tx9000418  1
2009 Vollrath AL, Smith AA, Craven M, Bradfield CA. EDGE(3): a web-based solution for management and analysis of Agilent two color microarray experiments. Bmc Bioinformatics. 10: 280. PMID 19732451 DOI: 10.1186/1471-2105-10-280  1
2009 Stevens EA, Mezrich JD, Bradfield CA. The aryl hydrocarbon receptor: a perspective on potential roles in the immune system. Immunology. 127: 299-311. PMID 19538249 DOI: 10.1111/j.1365-2567.2009.03054.x  1
2009 Smith AA, Vollrath A, Bradfield CA, Craven M. Clustered alignments of gene-expression time series data. Bioinformatics (Oxford, England). 25: i119-27. PMID 19477977 DOI: 10.1093/bioinformatics/btp206  1
2009 Nukaya M, Moran S, Bradfield CA. The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl hydrocarbon receptor biology. Proceedings of the National Academy of Sciences of the United States of America. 106: 4923-8. PMID 19261855 DOI: 10.1073/pnas.0809613106  1
2009 Nukaya M, Bradfield CA. Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive elements cluster. Biochemical Pharmacology. 77: 654-9. PMID 19026991 DOI: 10.1016/j.bcp.2008.10.026  1
2008 Lin BC, Nguyen LP, Walisser JA, Bradfield CA. A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse. Molecular Pharmacology. 74: 1367-71. PMID 18669605 DOI: 10.1124/mol.108.047068  1
2008 Bunger MK, Glover E, Moran SM, Walisser JA, Lahvis GP, Hsu EL, Bradfield CA. Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 106: 83-92. PMID 18660548 DOI: 10.1093/toxsci/kfn149  1
2008 Smith AA, Vollrath A, Bradfield CA, Craven M. Similarity queries for temporal toxicogenomic expression profiles. Plos Computational Biology. 4: e1000116. PMID 18636114 DOI: 10.1371/journal.pcbi.1000116  1
2008 Stevens EA, Bradfield CA. Immunology: T cells hang in the balance. Nature. 453: 46-7. PMID 18451850 DOI: 10.1038/453046a  1
2008 Westgate EJ, Cheng Y, Reilly DF, Price TS, Walisser JA, Bradfield CA, FitzGerald GA. Genetic components of the circadian clock regulate thrombogenesis in vivo. Circulation. 117: 2087-95. PMID 18413500 DOI: 10.1161/CIRCULATIONAHA.107.739227  1
2008 Kunieda T, Minamino T, Miura K, Katsuno T, Tateno K, Miyauchi H, Kaneko S, Bradfield CA, FitzGerald GA, Komuro I. Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circulation Research. 102: 607-14. PMID 18218984 DOI: 10.1161/CIRCRESAHA.107.162230  1
2008 Nguyen LP, Bradfield CA. The search for endogenous activators of the aryl hydrocarbon receptor. Chemical Research in Toxicology. 21: 102-16. PMID 18076143 DOI: 10.1021/tx7001965  1
2008 Vollrath AL, Bradfield CA. An Introduction to Toxicogenomics Drug Metabolism Handbook: Concepts and Applications. 737-759. DOI: 10.1002/9780470439265.ch25  1
2007 Hayes KR, Zastrow GM, Nukaya M, Pande K, Glover E, Maufort JP, Liss AL, Liu Y, Moran SM, Vollrath AL, Bradfield CA. Hepatic transcriptional networks induced by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemical Research in Toxicology. 20: 1573-81. PMID 17949056 DOI: 10.1021/tx7003294  1
2007 Lin BC, Sullivan R, Lee Y, Moran S, Glover E, Bradfield CA. Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality. The Journal of Biological Chemistry. 282: 35924-32. PMID 17916558 DOI: 10.1074/jbc.M705471200  1
2007 McMillan BJ, Bradfield CA. The aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems. Molecular Pharmacology. 72: 487-98. PMID 17535977 DOI: 10.1124/mol.107.037259  1
2007 McMillan BJ, McMillan SN, Glover E, Bradfield CA. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces premature activation of the KLF2 regulon during thymocyte development. The Journal of Biological Chemistry. 282: 12590-7. PMID 17337447 DOI: 10.1074/jbc.M611446200  1
2007 McMillan BJ, Bradfield CA. The aryl hydrocarbon receptor is activated by modified low-density lipoprotein. Proceedings of the National Academy of Sciences of the United States of America. 104: 1412-7. PMID 17227852 DOI: 10.1073/pnas.0607296104  1
2006 McDearmon EL, Patel KN, Ko CH, Walisser JA, Schook AC, Chong JL, Wilsbacher LD, Song EJ, Hong HK, Bradfield CA, Takahashi JS. Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (New York, N.Y.). 314: 1304-8. PMID 17124323 DOI: 10.1126/science.1132430  1
2006 Walisser JA, Bradfield CA. A time to divide: does the circadian clock control cell cycle? Developmental Cell. 10: 539-40. PMID 16678767 DOI: 10.1016/j.devcel.2006.04.014  1
2006 Dunham EE, Stevens EA, Glover E, Bradfield CA. The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein. Molecular Pharmacology. 70: 8-15. PMID 16582008 DOI: 10.1124/mol.106.024380  1
2006 Harstad EB, Guite CA, Thomae TL, Bradfield CA. Liver deformation in Ahr-null mice: evidence for aberrant hepatic perfusion in early development. Molecular Pharmacology. 69: 1534-41. PMID 16443691 DOI: 10.1124/mol.105.020107  1
2006 Thomae TL, Stevens EA, Liss AL, Drinkwater NR, Bradfield CA. The teratogenic sensitivity to 2,3,7,8-tetrachlorodibenzo-p-dioxin is modified by a locus on mouse chromosome 3. Molecular Pharmacology. 69: 770-5. PMID 16354765 DOI: 10.1124/mol.105.019760  1
2005 Walisser JA, Glover E, Pande K, Liss AL, Bradfield CA. Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types. Proceedings of the National Academy of Sciences of the United States of America. 102: 17858-63. PMID 16301529 DOI: 10.1073/pnas.0504757102  1
2005 Laposky A, Easton A, Dugovic C, Walisser J, Bradfield C, Turek F. Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation. Sleep. 28: 395-409. PMID 16171284  1
2005 Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Molecular and Cellular Biology. 25: 3163-72. PMID 15798202 DOI: 10.1128/MCB.25.8.3163-3172.2005  1
2005 Hayes KR, Bradfield CA. Advances in toxicogenomics. Chemical Research in Toxicology. 18: 403-14. PMID 15777080 DOI: 10.1021/tx0496690  0.88
2005 Bunger MK, Walisser JA, Sullivan R, Manley PA, Moran SM, Kalscheur VL, Colman RJ, Bradfield CA. Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus. Genesis (New York, N.Y. : 2000). 41: 122-32. PMID 15739187 DOI: 10.1002/gene.20102  1
2005 Pande K, Moran SM, Bradfield CA. Aspects of dioxin toxicity are mediated by interleukin 1-like cytokines. Molecular Pharmacology. 67: 1393-8. PMID 15722456 DOI: 10.1124/mol.105.010983  1
2005 Thomae TL, Stevens EA, Bradfield CA. Transforming growth factor-beta3 restores fusion in palatal shelves exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. The Journal of Biological Chemistry. 280: 12742-6. PMID 15668235 DOI: 10.1074/jbc.M410780200  1
2005 Hayes KR, Vollrath AL, Zastrow GM, McMillan BJ, Craven M, Jovanovich S, Rank DR, Penn S, Walisser JA, Reddy JK, Thomas RS, Bradfield CA. EDGE: a centralized resource for the comparison, analysis, and distribution of toxicogenomic information. Molecular Pharmacology. 67: 1360-8. PMID 15662043 DOI: 10.1124/mol.104.009175  0.92
2005 Lahvis GP, Pyzalski RW, Glover E, Pitot HC, McElwee MK, Bradfield CA. The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse. Molecular Pharmacology. 67: 714-20. PMID 15590894 DOI: 10.1124/mol.104.008888  1
2005 Williams SN, Dunham E, Bradfield CA. Induction of cytochrome P450 enzymes Cytochrome P450: Structure, Mechanism, and Biochemistry: Third Edition. 323-346. DOI: 10.1007/0-387-27447-2_8  1
2004 Walisser JA, Bunger MK, Glover E, Bradfield CA. Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development. Proceedings of the National Academy of Sciences of the United States of America. 101: 16677-82. PMID 15545609 DOI: 10.1073/pnas.0404379101  1
2004 Thomae TL, Glover E, Bradfield CA. A maternal Ahr null genotype sensitizes embryos to chemical teratogenesis. The Journal of Biological Chemistry. 279: 30189-94. PMID 15145931 DOI: 10.1074/jbc.M403690200  1
2004 Yao G, Craven M, Drinkwater N, Bradfield CA. Interaction networks in yeast define and enumerate the signaling steps of the vertebrate aryl hydrocarbon receptor. Plos Biology. 2: E65. PMID 15024417 DOI: 10.1371/journal.pbio.0020065  1
2004 Peter Guengerich F, Martin MV, McCormick WA, Nguyen LP, Glover E, Bradfield CA. Aryl hydrocarbon receptor response to indigoids in vitro and in vivo. Archives of Biochemistry and Biophysics. 423: 309-16. PMID 15001395 DOI: 10.1016/j.abb.2004.01.002  1
2004 Walisser JA, Bunger MK, Glover E, Harstad EB, Bradfield CA. Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele. The Journal of Biological Chemistry. 279: 16326-31. PMID 14764592 DOI: 10.1074/jbc.M400784200  1
2004 Bradfield C. Genomics and proteomics. Chemical Research in Toxicology. 17: 2. PMID 14727913 DOI: 10.1021/tx0342619  1
2003 Bittinger MA, Nguyen LP, Bradfield CA. Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor. Molecular Pharmacology. 64: 550-6. PMID 12920190 DOI: 10.1124/mol.64.3.550  1
2003 Bunger MK, Moran SM, Glover E, Thomae TL, Lahvis GP, Lin BC, Bradfield CA. Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 278: 17767-74. PMID 12621046 DOI: 10.1074/jbc.M209594200  1
2002 Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Hu T, Pande K, Lewis M, Jovanovich SB, Bradfield CA. Application of genomics to toxicology research. Environmental Health Perspectives. 110: 919-23. PMID 12634120  0.88
2002 Thomas RS, Rank DR, Penn SG, Craven MW, Drinkwater NR, Bradfield CA. Developing toxicologically predictive gene sets using cDNA microarrays and Bayesian classification. Methods in Enzymology. 357: 198-205. PMID 12424911 DOI: 10.1016/S0076-6879(02)57679-5  1
2002 Thomas RS, Penn SG, Holden K, Bradfield CA, Rank DR. Sequence variation and phylogenetic history of the mouse Ahr gene. Pharmacogenetics. 12: 151-63. PMID 11875369 DOI: 10.1097/00008571-200203000-00009  1
2001 Cherkaoui-Malki M, Meyer K, Cao WQ, Latruffe N, Yeldandi AV, Rao MS, Bradfield CA, Reddy JK. Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis. Gene Expression. 9: 291-304. PMID 11764000  1
2001 Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Pande K, Glover E, Silander T, Craven MW, Reddy JK, Jovanovich SB, Bradfield CA. Identification of toxicologically predictive gene sets using cDNA microarrays. Molecular Pharmacology. 60: 1189-94. PMID 11723225  0.88
2000 Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 103: 1009-17. PMID 11163178 DOI: 10.1016/S0092-8674(00)00205-1  1
2000 Lahvis GP, Lindell SL, Thomas RS, McCuskey RS, Murphy C, Glover E, Bentz M, Southard J, Bradfield CA. Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 10442-7. PMID 10973493 DOI: 10.1073/pnas.190256997  1
2000 Hogenesch JB, Gu YZ, Moran SM, Shimomura K, Radcliffe LA, Takahashi JS, Bradfield CA. The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC83. PMID 10864977  1
2000 Gu YZ, Hogenesch JB, Bradfield CA. The PAS superfamily: sensors of environmental and developmental signals. Annual Review of Pharmacology and Toxicology. 40: 519-61. PMID 10836146 DOI: 10.1146/annurev.pharmtox.40.1.519  0.76
2000 LaPres JJ, Glover E, Dunham EE, Bunger MK, Bradfield CA. ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor. The Journal of Biological Chemistry. 275: 6153-9. PMID 10692406 DOI: 10.1074/jbc.275.9.6153  1
1999 Chan WK, Yao G, Gu YZ, Bradfield CA. Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation. The Journal of Biological Chemistry. 274: 12115-23. PMID 10207038 DOI: 10.1074/jbc.274.17.12115  1
1998 Bunger MK, Bradfield CA. Generation of allelic series in mice by gene targeting. Methods in Molecular Biology (Clifton, N.J.). 107: 439-68. PMID 14577251 DOI: 10.1385/0-89603-519-0:439  1
1998 Gu YZ, Moran SM, Hogenesch JB, Wartman L, Bradfield CA. Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. Gene Expression. 7: 205-13. PMID 9840812  1
1998 Carver LA, LaPres JJ, Jain S, Dunham EE, Bradfield CA. Characterization of the Ah receptor-associated protein, ARA9. The Journal of Biological Chemistry. 273: 33580-7. PMID 9837941 DOI: 10.1074/jbc.273.50.33580  1
1998 Lahvis GP, Bradfield CA. Ahr null alleles: distinctive or different? Biochemical Pharmacology. 56: 781-7. PMID 9774139 DOI: 10.1016/S0006-2952(98)00134-8  1
1998 Hogenesch JB, Gu YZ, Jain S, Bradfield CA. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proceedings of the National Academy of Sciences of the United States of America. 95: 5474-9. PMID 9576906  0.76
1998 Jain S, Maltepe E, Lu MM, Simon C, Bradfield CA. Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mechanisms of Development. 73: 117-23. PMID 9545558 DOI: 10.1016/S0925-4773(98)00038-0  1
1998 Powell-Coffman JA, Bradfield CA, Wood WB. Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator. Proceedings of the National Academy of Sciences of the United States of America. 95: 2844-9. PMID 9501178 DOI: 10.1073/pnas.95.6.2844  1
1997 Luo G, Gu YZ, Jain S, Chan WK, Carr KM, Hogenesch JB, Bradfield CA. Molecular characterization of the murine Hif-1 alpha locus. Gene Expression. 6: 287-99. PMID 9368100  1
1997 Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature. 386: 403-7. PMID 9121557 DOI: 10.1038/386403a0  1
1997 Carver LA, Bradfield CA. Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. The Journal of Biological Chemistry. 272: 11452-6. PMID 9111057 DOI: 10.1074/jbc.272.17.11452  1
1997 Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu YZ, Pray-Grant M, Perdew GH, Bradfield CA. Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. The Journal of Biological Chemistry. 272: 8581-93. PMID 9079689 DOI: 10.1074/jbc.272.13.8581  1
1996 Schmidt JV, Bradfield CA. Ah receptor signaling pathways. Annual Review of Cell and Developmental Biology. 12: 55-89. PMID 8970722 DOI: 10.1146/annurev.cellbio.12.1.55  1
1996 Perdew GH, Bradfield CA. Mapping the 90 kDa heat shock protein binding region of the Ah receptor. Biochemistry and Molecular Biology International. 39: 589-93. PMID 8828811  1
1996 Schmidt JV, Su GH, Reddy JK, Simon MC, Bradfield CA. Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proceedings of the National Academy of Sciences of the United States of America. 93: 6731-6. PMID 8692887 DOI: 10.1073/pnas.93.13.6731  1
1995 Swanson HI, Chan WK, Bradfield CA. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. The Journal of Biological Chemistry. 270: 26292-302. PMID 7592839 DOI: 10.1074/jbc.270.44.26292  1
1994 Huang Q, Alvares K, Chu R, Bradfield CA, Reddy JK. Association of peroxisome proliferator-activated receptor and Hsp72. The Journal of Biological Chemistry. 269: 8493-7. PMID 8132576  1
1994 Le Beau MM, Carver LA, Espinosa R, Schmidt JV, Bradfield CA. Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15. Cytogenetics and Cell Genetics. 66: 172-6. PMID 8125016  1
1994 Carver LA, Hogenesch JB, Bradfield CA. Tissue specific expression of the rat Ah-receptor and ARNT mRNAs. Nucleic Acids Research. 22: 3038-44. PMID 8065918  0.76
1994 Bradfield CA, Gallo MA, Gasiewicz TA, Greenberg RS, Greenlee WF, Margolick J, Mattison DR, Munson P, Neal RA, Okey AB. EPA dioxin reassessment. Science (New York, N.Y.). 266: 1628-9. PMID 7992038  1
1994 Jain S, Dolwick KM, Schmidt JV, Bradfield CA. Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxyl termini. The Journal of Biological Chemistry. 269: 31518-24. PMID 7989319  1
1994 Carver LA, Jackiw V, Bradfield CA. The 90-kDa heat shock protein is essential for Ah receptor signaling in a yeast expression system. The Journal of Biological Chemistry. 269: 30109-12. PMID 7982913  1
1994 Chan WK, Chu R, Jain S, Reddy JK, Bradfield CA. Baculovirus expression of the Ah receptor and Ah receptor nuclear translocater. Evidence for additional dioxin responsive element-binding species and factors required for signaling. The Journal of Biological Chemistry. 269: 26464-71. PMID 7929368  1
1993 Schmidt JV, Carver LA, Bradfield CA. Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment. The Journal of Biological Chemistry. 268: 22203-9. PMID 8408082  1
1993 Dolwick KM, Swanson HI, Bradfield CA. In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition. Proceedings of the National Academy of Sciences of the United States of America. 90: 8566-70. PMID 8397410  1
1993 Swanson HI, Bradfield CA. The AH-receptor: genetics, structure and function. Pharmacogenetics. 3: 213-30. PMID 8287061  1
1993 Dolwick KM, Schmidt JV, Carver LA, Swanson HI, Bradfield CA. Cloning and expression of a human Ah receptor cDNA. Molecular Pharmacology. 44: 911-7. PMID 8246913  1
1992 Poland A, Bradfield C. A brief review of the Ah locus. The Tohoku Journal of Experimental Medicine. 168: 83-7. PMID 1339107  1
1992 Burbach KM, Poland A, Bradfield CA. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 8185-9. PMID 1325649  1
1991 Bradfield CA, Bjeldanes LF. Modification of carcinogen metabolism by indolylic autolysis products of Brassica oleraceae. Advances in Experimental Medicine and Biology. 289: 153-63. PMID 1897390  1
1991 Poland A, Glover E, Bradfield CA. Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten. Molecular Pharmacology. 39: 20-6. PMID 1846218  1
1991 Bradfield CA, Glover E, Poland A. Purification and N-terminal amino acid sequence of the Ah receptor from the C57BL/6J mouse. Molecular Pharmacology. 39: 13-9. PMID 1846217  1
1991 Bjeldanes LF, Kim JY, Grose KR, Bartholomew JC, Bradfield CA. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proceedings of the National Academy of Sciences of the United States of America. 88: 9543-7. PMID 1658785  1
1988 Bradfield CA, Poland A. A competitive binding assay for 2,3,7,8-tetrachlorodibenzo-p-dioxin and related ligands of the Ah receptor. Molecular Pharmacology. 34: 682-8. PMID 2848187  1
1988 Bradfield CA, Kende AS, Poland A. Kinetic and equilibrium studies of Ah receptor-ligand binding: use of [125I]2-iodo-7,8-dibromodibenzo-p-dioxin. Molecular Pharmacology. 34: 229-37. PMID 2842655  1
1987 Bradfield CA, Bjeldanes LF. Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism. Journal of Toxicology and Environmental Health. 21: 311-23. PMID 3495667 DOI: 10.1080/15287398709531021  1
1987 Bradfield CA, Bjeldanes LF. High-performance liquid chromatographic analysis of anticarcinogenic indoles in Brassica oleracea Journal of Agricultural and Food Chemistry. 35: 46-49.  1
1987 Bradfield CA, Bjeldanes LF. Dietary modification of xenobiotic metabolism: Contribution of indolylic compounds present in Brassica oleracea Journal of Agricultural and Food Chemistry. 35: 896-900.  1
1985 Bradfield CA, Chang Y, Bjeldanes LF. Effects of commonly consumed vegetables on hepatic xenobiotic-metabolizing enzymes in the mouse. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 23: 899-904. PMID 3877667 DOI: 10.1016/0278-6915(85)90105-X  1
1985 Bradfield CA, Bjeldanes LF. Effects of dietary cauliflower, indole-3-carbinol and its structural analogs on xenobiotic metabolism in the rat and mouse Federation Proceedings. 44: No. 7378.  1
1984 Bradfield CA, Bjeldanes LF. Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 22: 977-82. PMID 6334634 DOI: 10.1016/0278-6915(84)90147-9  1
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