Year |
Citation |
Score |
2021 |
Okuyama S, Sawamoto A, Nakajima M, Furukawa Y. [The Search for Citrus Components with Neuroprotective and Anti-dementia Effects in the Mouse Brain]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 141: 819-824. PMID 34078788 DOI: 10.1248/yakushi.20-00251-1 |
0.362 |
|
2020 |
Okuyama S, Sawamoto A, Nakajima M, Furukawa Y. [Neuroprotective effects of the peel of Citrus kawachiensis (Kawachi Bankan) and auraptene in the hippocampus of hyperglycemia mice and global cerebral ischemia/reperfusion injury mice]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 155: 214-219. PMID 32612031 DOI: 10.1254/Fpj.20022 |
0.425 |
|
2020 |
Furukawa Y, Washimi YS, Hara RI, Yamaoka M, Okuyama S, Sawamoto A, Nakajima M. Citrus Auraptene Induces Expression of Brain-Derived Neurotrophic Factor in Neuro2a Cells. Molecules (Basel, Switzerland). 25. PMID 32138196 DOI: 10.3390/Molecules25051117 |
0.4 |
|
2019 |
Furukawa Y, Hara RI, Nakaya M, Okuyama S, Sawamoto A, Nakajima M. Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells. International Journal of Molecular Sciences. 21. PMID 31905925 DOI: 10.3390/Ijms21010253 |
0.424 |
|
2019 |
Sawamoto A, Nakanishi M, Okuyama S, Furukawa Y, Nakajima M. Heptamethoxyflavone inhibits adipogenesis via enhancing PKA signaling. European Journal of Pharmacology. 172758. PMID 31672599 DOI: 10.1016/J.Ejphar.2019.172758 |
0.347 |
|
2019 |
Haramiishi R, Okuyama S, Yoshimura M, Nakajima M, Furukawa Y, Ito H, Amakura Y. Identification of the characteristic components in walnut and anti-inflammatory effect of glansreginin A as an indicator for quality evaluation. Bioscience, Biotechnology, and Biochemistry. 1-11. PMID 31566092 DOI: 10.1080/09168451.2019.1670046 |
0.367 |
|
2019 |
Sawamoto A, Okuyama S, Nakajima M, Furukawa Y. Citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone induces BDNF via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells. Pharmacological Reports : Pr. 71: 653-658. PMID 31195342 DOI: 10.1016/J.Pharep.2019.03.006 |
0.347 |
|
2019 |
Okuyama S, Kanzaki T, Kotani Y, Katoh M, Sawamoto A, Nakajima M, Furukawa Y. Continual Treatment with the Peels of Citrus kawachiensis (Kawachi Bankan) Protects against Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's Disease. Journal of Nutritional Science and Vitaminology. 65: 205-208. PMID 31061292 DOI: 10.3177/Jnsv.65.205 |
0.361 |
|
2019 |
Furukawa Y, Sawamoto A, Yamaoka M, Nakaya M, Hieda Y, Choshi T, Hatae N, Okuyama S, Nakajima M, Hibino S. Effects of Carbazole Derivatives on Neurite Outgrowth and Hydrogen Peroxide-Induced Cytotoxicity in Neuro2a Cells. Molecules (Basel, Switzerland). 24. PMID 30959983 DOI: 10.3390/Molecules24071366 |
0.324 |
|
2019 |
Okuyama S, Katoh M, Kanzaki T, Kotani Y, Amakura Y, Yoshimura M, Fukuda N, Tamai T, Sawamoto A, Nakajima M, Furukawa Y. Auraptene/Naringin-Rich Fruit Juice of Citrus kawachiensis (Kawachi Bankan) Prevents Ischemia-Induced Neuronal Cell Death in Mouse Brain through Anti-Inflammatory Responses. Journal of Nutritional Science and Vitaminology. 65: 66-71. PMID 30814414 DOI: 10.3177/Jnsv.65.66 |
0.405 |
|
2018 |
Okuyama S, Nakashima T, Nakamura K, Shinoka W, Kotani M, Sawamoto A, Nakajima M, Furukawa Y. Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice. Antioxidants (Basel, Switzerland). 7. PMID 30126250 DOI: 10.3390/Antiox7080109 |
0.451 |
|
2018 |
Okuyama S, Shinoka W, Nakamura K, Kotani M, Sawamoto A, Sugawara K, Sudo M, Nakajima M, Furukawa Y. Suppressive effects of the peel of Citrus kawachiensis (Kawachi Bankan) on astroglial activation, tau phosphorylation, and inhibition of neurogenesis in the hippocampus of type 2 diabetic db/db mice. Bioscience, Biotechnology, and Biochemistry. 1-12. PMID 29732953 DOI: 10.1080/09168451.2018.1469396 |
0.427 |
|
2018 |
Okuyama S, Yamamoto K, Mori H, Sawamoto A, Amakura Y, Yoshimura M, Tamanaha A, Ohkubo Y, Sugawara K, Sudo M, Nakajima M, Furukawa Y. Neuroprotective effect of Citrus kawachiensis (Kawachi Bankan) peels, a rich source of naringin, against global cerebral ischemia/reperfusion injury in mice. Bioscience, Biotechnology, and Biochemistry. 1-9. PMID 29618282 DOI: 10.1080/09168451.2018.1456320 |
0.427 |
|
2018 |
Okuyama S, Kotani Y, Yamamoto K, Sawamoto A, Sugawara K, Sudo M, Ohkubo Y, Tamanaha A, Nakajima M, Furukawa Y. The peel of Citrus kawachiensis (kawachi bankan) ameliorates microglial activation, tau hyper-phosphorylation, and suppression of neurogenesis in the hippocampus of senescence-accelerated mice. Bioscience, Biotechnology, and Biochemistry. 1-10. PMID 29424280 DOI: 10.1080/09168451.2018.1433993 |
0.459 |
|
2017 |
Hamada Y, Nakajima M, Tsuzuki K, Amakura Y, Yoshimura M, Okuyama S, Furukawa Y. Heptamethoxyflavone Reduces Phosphodiesterase Activity and T-Cell Growth in vitro. International Archives of Allergy and Immunology. PMID 29130985 DOI: 10.1159/000481094 |
0.309 |
|
2017 |
Sawamoto A, Okuyama S, Amakura Y, Yoshimura M, Yamada T, Yokogoshi H, Nakajima M, Furukawa Y. 3,5,6,7,8,3',4'-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation. International Journal of Molecular Sciences. 18. PMID 29023414 DOI: 10.3390/Ijms18102133 |
0.368 |
|
2017 |
Sawamoto A, Okuyama S, Amakura Y, Yamada R, Yoshimura M, Nakajima M, Furukawa Y. Sansoninto as evidence-based remedial medicine for depression-like behavior. Journal of Natural Medicines. PMID 28825180 DOI: 10.1007/S11418-017-1119-0 |
0.348 |
|
2017 |
Okuyama S, Miyazaki K, Yamada R, Amakura Y, Yoshimura M, Sawamoto A, Nakajima M, Furukawa Y. Permeation of Polymethoxyflavones into the Mouse Brain and Their Effect on MK-801-Induced Locomotive Hyperactivity. International Journal of Molecular Sciences. 18. PMID 28245567 DOI: 10.3390/Ijms18030489 |
0.391 |
|
2016 |
Okuyama S, Semba T, Toyoda N, Epifano F, Genovese S, Fiorito S, Taddeo VA, Sawamoto A, Nakajima M, Furukawa Y. Auraptene and Other Prenyloxyphenylpropanoids Suppress Microglial Activation and Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's Disease. International Journal of Molecular Sciences. 17. PMID 27763495 DOI: 10.3390/Ijms17101716 |
0.39 |
|
2016 |
Nakajima M, Watanabe T, Aoki R, Shimizu R, Okuyama S, Furukawa Y. Phenotypes Associated with Psychiatric Disorders are Sex-Specific in a Mutant Mouse Line. Brain Research. PMID 27693417 DOI: 10.1016/J.Brainres.2016.09.037 |
0.302 |
|
2016 |
Sawamoto A, Okuyama S, Yamamoto K, Amakura Y, Yoshimura M, Nakajima M, Furukawa Y. 3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus. Molecules (Basel, Switzerland). 21. PMID 27120588 DOI: 10.3390/Molecules21040541 |
0.349 |
|
2016 |
Nakajima M, Shimizu R, Furuta K, Sugino M, Watanabe T, Aoki R, Okuyama S, Furukawa Y. Auraptene induces oligodendrocyte lineage precursor cells in a cuprizone-induced animal model of demyelination. Brain Research. PMID 26944297 DOI: 10.1016/J.Brainres.2016.02.041 |
0.319 |
|
2015 |
Okuyama S, Morita M, Kaji M, Amakura Y, Yoshimura M, Shimamoto K, Ookido Y, Nakajima M, Furukawa Y. Auraptene Acts as an Anti-Inflammatory Agent in the Mouse Brain. Molecules (Basel, Switzerland). 20: 20230-20239. PMID 26569206 DOI: 10.3390/Molecules201119691 |
0.433 |
|
2015 |
Okuyama S. [Effects of Bioactive Substances from Citrus on the Central Nervous System and Utilization as Food Material]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 135: 1153-9. PMID 26423872 DOI: 10.1248/Yakushi.15-00205 |
0.416 |
|
2015 |
Okuyama S, Miyoshi K, Tsumura Y, Amakura Y, Yoshimura M, Yoshida T, Nakajima M, Furukawa Y. 3,5,6,7,8,3',4'-heptamethoxyflavone, a citrus polymethoxylated flavone, attenuates inflammation in the mouse hippocampus. Brain Sciences. 5: 118-29. PMID 25884208 DOI: 10.3390/Brainsci5020118 |
0.38 |
|
2015 |
Okuyama S, Morita M, Sawamoto A, Terugo T, Nakajima M, Furukawa Y. Edaravone enhances brain-derived neurotrophic factor production in the ischemic mouse brain. Pharmaceuticals (Basel, Switzerland). 8: 176-85. PMID 25850013 DOI: 10.3390/Ph8020176 |
0.399 |
|
2015 |
Nakajima M, Shimizu R, Furuta K, Sugino M, Watanabe T, Aoki R, Okuyama S, Furukawa Y. Nobiletin Induces Oligodendrocyte Lineage Precursor Cells in a Cuprizone-Administered Demyelination Animal Model Journal of Multiple Sclerosis. 2015: 1-6. DOI: 10.4172/2376-0389.1000153 |
0.324 |
|
2014 |
Okuyama S, Yamamoto K, Mori H, Toyoda N, Yoshimura M, Amakura Y, Yoshida T, Sugawara K, Sudo M, Nakajima M, Furukawa Y. Auraptene in the Peels of Citrus kawachiensis (Kawachi Bankan) Ameliorates Lipopolysaccharide-Induced Inflammation in the Mouse Brain. Evidence-Based Complementary and Alternative Medicine : Ecam. 2014: 408503. PMID 24955102 DOI: 10.1155/2014/408503 |
0.36 |
|
2014 |
Okuyama S, Morita M, Miyoshi K, Nishigawa Y, Kaji M, Sawamoto A, Terugo T, Toyoda N, Makihata N, Amakura Y, Yoshimura M, Nakajima M, Furukawa Y. 3,5,6,7,8,3',4'-Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model. Neurochemistry International. 70: 30-8. PMID 24657445 DOI: 10.1016/J.Neuint.2014.03.008 |
0.357 |
|
2013 |
Nakajima M, Kawamura T, Tokui R, Furuta K, Sugino M, Nakanishi M, Okuyama S, Furukawa Y. Enhanced accumulation of Kir4.1 protein, but not mRNA, in a murine model of cuprizone-induced demyelination. Brain Research. 1537: 340-9. PMID 24070676 DOI: 10.1016/J.Brainres.2013.09.024 |
0.359 |
|
2013 |
Okuyama S, Makihata N, Yoshimura M, Amakura Y, Yoshida T, Nakajima M, Furukawa Y. Oenothein B Suppresses Lipopolysaccharide (LPS)-Induced Inflammation in the Mouse Brain. International Journal of Molecular Sciences. 14: 9767-78. PMID 23652834 DOI: 10.3390/Ijms14059767 |
0.379 |
|
2013 |
Okuyama S, Minami S, Shimada N, Makihata N, Nakajima M, Furukawa Y. Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice. European Journal of Pharmacology. 699: 118-23. PMID 23219792 DOI: 10.1016/J.Ejphar.2012.11.043 |
0.409 |
|
2013 |
Nakajima M, Mori H, Nishikawa C, Tsuruta M, Okuyama S, Furukawa Y. Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice. Journal of Neurochemistry. 124: 241-9. PMID 23134367 DOI: 10.1111/Jnc.12085 |
0.312 |
|
2012 |
Okuyama S, Shimada N, Kaji M, Morita M, Miyoshi K, Minami S, Amakura Y, Yoshimura M, Yoshida T, Watanabe S, Nakajima M, Furukawa Y. Heptamethoxyflavone, a citrus flavonoid, enhances brain-derived neurotrophic factor production and neurogenesis in the hippocampus following cerebral global ischemia in mice. Neuroscience Letters. 528: 190-5. PMID 22985518 DOI: 10.1016/J.Neulet.2012.08.079 |
0.418 |
|
2012 |
Furukawa Y, Watanabe S, Okuyama S, Nakajima M. Neurotrophic effect of citrus auraptene: neuritogenic activity in PC12 cells. International Journal of Molecular Sciences. 13: 5338-47. PMID 22754300 DOI: 10.3390/Ijms13055338 |
0.367 |
|
2012 |
Furukawa Y, Okuyama S, Amakura Y, Watanabe S, Fukata T, Nakajima M, Yoshimura M, Yoshida T. Isolation and characterization of activators of ERK/MAPK from citrus plants. International Journal of Molecular Sciences. 13: 1832-45. PMID 22408427 DOI: 10.3390/Ijms13021832 |
0.35 |
|
2011 |
Nakajima M, Matsuda K, Miyauchi N, Fukunaga Y, Watanabe S, Okuyama S, Pérez J, Fernández-Llebrez P, Shen J, Furukawa Y. Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages. Brain Research. 1382: 275-81. PMID 21262207 DOI: 10.1016/J.Brainres.2011.01.048 |
0.333 |
|
2011 |
Nakajima M, Matsuda K, Miyauchi N, Fukunaga Y, Watanabe S, Okuyama S, Pérez J, Fernández-Llebrez P, Shen J, Furukawa Y. ErratumCorrigendum to “Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages” [Brain Res. 1382 (2011) 275–281] Brain Research. 1395: 116. DOI: 10.1016/J.Brainres.2011.04.027 |
0.324 |
|
2010 |
Tokuraku K, Okuyama S, Matsushima K, Ikezu T, Kotani S. Distinct neuronal localization of microtubule-associated protein 4 in the mammalian brain. Neuroscience Letters. 484: 143-7. PMID 20727942 DOI: 10.1016/J.Neulet.2010.08.038 |
0.56 |
|
2010 |
Kiyota T, Okuyama S, Swan RJ, Jacobsen MT, Gendelman HE, Ikezu T. CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3093-102. PMID 20371618 DOI: 10.1096/Fj.10-155317 |
0.725 |
|
2010 |
Xu J, Sato S, Okuyama S, Swan RJ, Jacobsen MT, Strunk E, Ikezu T. Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2904-15. PMID 20354135 DOI: 10.1096/Fj.09-150144 |
0.696 |
|
2010 |
Furukawa Y, Urano T, Minamimura M, Nakajima M, Okuyama S, Furukawa S. 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway. Biomedical Research (Tokyo, Japan). 31: 45-52. PMID 20203419 DOI: 10.2220/Biomedres.31.45 |
0.34 |
|
2009 |
Buescher JL, Martinez LB, Sato S, Okuyama S, Ikezu T. YY1 and FoxD3 regulate antiretroviral zinc finger protein OTK18 promoter activation induced by HIV-1 infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 103-15. PMID 19034670 DOI: 10.1007/S11481-008-9139-X |
0.548 |
|
2008 |
Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T. Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14511-21. PMID 19118186 DOI: 10.1523/Jneurosci.3417-08.2008 |
0.705 |
|
2008 |
Lyou S, Kawano S, Yamada T, Okuyama S, Terashima T, Hayase K, Yokogoshi H. Role of estrogen receptors and aromatase on brain protein synthesis rates in ovariectomized female rats fed genistein. Nutritional Neuroscience. 11: 155-60. PMID 18681983 DOI: 10.1179/147683008X301559 |
0.313 |
|
2008 |
Ikezu T, Kiyota T, Yamamoto M, Xu J, Jacobsen MT, Okuyama S. O1-04-08: Therapeutic application of anti-inflammatory cytokines an Abeta-induced cognitive dysfunction Alzheimer's & Dementia. 4: T116-T117. DOI: 10.1016/J.Jalz.2008.05.245 |
0.629 |
|
2002 |
Hirano E, Lyou S, Tujioka K, Tanaka M, Hayase K, Okuyama S, Yokogoshi H. Effects of quantity and quality of dietary protein on the brain polysome profile in aged rats. Bioscience, Biotechnology, and Biochemistry. 66: 351-5. PMID 11999408 DOI: 10.1271/Bbb.66.351 |
0.3 |
|
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