| Year |
Citation |
Score |
| 2023 |
Howard E, Hurrell BP, Helou DG, Shafiei-Jahani P, Hasiakos S, Painter J, Srikanth S, Gwack Y, Akbari O. Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models. Nature Communications. 14: 5989. PMID 37752127 DOI: 10.1038/s41467-023-41065-4 |
0.528 |
|
| 2022 |
Wu B, Woo JS, Sun Z, Srikanth S, Gwack Y. Ca Signaling Augmented by ORAI1 Trafficking Regulates the Pathogenic State of Effector T Cells. Journal of Immunology (Baltimore, Md. : 1950). 208: 1329-1340. PMID 35217583 DOI: 10.4049/jimmunol.2100871 |
0.547 |
|
| 2021 |
Wu B, Ramaiah A, Garcia G, Hasiakos S, Arumugaswami V, Srikanth S. ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 34819389 DOI: 10.4049/jimmunol.2100742 |
0.432 |
|
| 2021 |
Wu B, Woo JS, Vila P, Jew M, Leung J, Sun Z, Srikanth S, Gwack Y. NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca entry in T cells. Cell Reports. 36: 109603. PMID 34433025 DOI: 10.1016/j.celrep.2021.109603 |
0.465 |
|
| 2021 |
Wu B, Ramaiah A, Garcia G, Gwack Y, Arumugaswami V, Srikanth S. ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling. Biorxiv : the Preprint Server For Biology. PMID 33972946 DOI: 10.1101/2021.05.04.442548 |
0.44 |
|
| 2021 |
Srikanth S, Gwack Y. Blue light opens the ORAI1 LOC(K). Cell Calcium. 95: 102371. PMID 33626404 DOI: 10.1016/j.ceca.2021.102371 |
0.504 |
|
| 2020 |
Woo JS, Sun Z, Srikanth S, Gwack Y. The short isoform of extended synaptotagmin-2 controls Ca dynamics in T cells via interaction with STIM1. Scientific Reports. 10: 14433. PMID 32879390 DOI: 10.1038/S41598-020-71489-7 |
0.55 |
|
| 2019 |
Srikanth S, Woo JS, Wu B, El-Sherbiny YM, Leung J, Chupradit K, Rice L, Seo GJ, Calmettes G, Ramakrishna C, Cantin E, An DS, Sun R, Wu TT, Jung JU, et al. The Ca sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. Nature Immunology. PMID 30643259 DOI: 10.1038/S41590-018-0287-8 |
0.449 |
|
| 2018 |
Woo JS, Srikanth S, Kim KD, Elsaesser H, Lu J, Pellegrini M, Brooks DG, Sun Z, Gwack Y. CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 29987160 DOI: 10.4049/Jimmunol.1800659 |
0.43 |
|
| 2018 |
Choi H, Srikanth S, Atti E, Pirih FQ, Nervina JM, Gwack Y, Tetradis S. Deletion of Orai1 leads to bone loss aggravated with aging and impairs function of osteoblast lineage cells. Bone Reports. 8: 147-155. PMID 29955633 DOI: 10.1016/J.Bonr.2018.03.007 |
0.326 |
|
| 2017 |
Srikanth S, Woo JS, Sun Z, Gwack Y. Immunological Disorders: Regulation of Ca(2+) Signaling in T Lymphocytes. Advances in Experimental Medicine and Biology. 993: 397-424. PMID 28900926 DOI: 10.1007/978-3-319-57732-6_21 |
0.605 |
|
| 2017 |
Choi D, Park E, Jung E, Seong YJ, Yoo J, Lee E, Hong M, Lee S, Ishida H, Burford J, Peti-Peterdi J, Adams RH, Srikanth S, Gwack Y, Chen CS, et al. Laminar flow downregulates Notch activity to promote lymphatic sprouting. The Journal of Clinical Investigation. PMID 28263185 DOI: 10.1172/Jci87442 |
0.36 |
|
| 2016 |
Lee SH, Rigas NK, Lee CR, Bang A, Srikanth S, Gwack Y, Kang MK, Kim RH, Park NH, Shin KH. Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma. Oncotarget. PMID 27259269 DOI: 10.18632/Oncotarget.9755 |
0.359 |
|
| 2016 |
Srikanth S, Woo JS, Gwack Y. A large Rab GTPase family in a small GTPase world. Small Gtpases. 0. PMID 27221160 DOI: 10.1080/21541248.2016.1192921 |
0.368 |
|
| 2016 |
Lee SH, Park Y, Song M, Srikanth S, Kim S, Kang MK, Gwack Y, Park NH, Kim RH, Shin KH. Orai1 mediates osteogenic differentiation via BMP signaling pathway in bone marrow mesenchymal stem cells. Biochemical and Biophysical Research Communications. PMID 27086849 DOI: 10.1016/J.Bbrc.2016.04.068 |
0.452 |
|
| 2016 |
Srikanth S, Kim KD, Gao Y, Woo JS, Ghosh S, Calmettes G, Paz A, Abramson J, Jiang M, Gwack Y. A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals. Science Signaling. 9: ra31. PMID 27016526 DOI: 10.1126/Scisignal.Aac9171 |
0.502 |
|
| 2016 |
Woo JS, Srikanth S, Nishi M, Ping P, Takeshima H, Gwack Y. Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929330 DOI: 10.1073/Pnas.1524229113 |
0.583 |
|
| 2015 |
Nurbaeva MK, Eckstein M, Concepcion AR, Smith CE, Srikanth S, Paine ML, Gwack Y, Hubbard MJ, Feske S, Lacruz RS. Dental enamel cells express functional SOCE channels. Scientific Reports. 5: 15803. PMID 26515404 DOI: 10.1038/Srep15803 |
0.673 |
|
| 2015 |
Sohn S, Park Y, Srikanth S, Arai A, Song M, Yu B, Shin KH, Kang MK, Wang C, Gwack Y, Park NH, Kim RH. The Role of ORAI1 in the Odontogenic Differentiation of Human Dental Pulp Stem Cells. Journal of Dental Research. PMID 26403672 DOI: 10.1177/0022034515608128 |
0.544 |
|
| 2014 |
Bertin S, Aoki-Nonaka Y, de Jong PR, Nohara LL, Xu H, Stanwood SR, Srikanth S, Lee J, To K, Abramson L, Yu T, Han T, Touma R, Li X, González-Navajas JM, et al. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells. Nature Immunology. 15: 1055-63. PMID 25282159 DOI: 10.1038/Ni.3009 |
0.474 |
|
| 2014 |
Srikanth S, Kim KD, Gwack Y. Methods to measure cytoplasmic and mitochondrial Ca(2+) concentration using Ca(2+)-sensitive dyes. Methods in Enzymology. 543: 1-20. PMID 24924125 DOI: 10.1016/B978-0-12-801329-8.00001-5 |
0.65 |
|
| 2014 |
Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim do H, Baretta K, Srikanth S, Gwack Y, Ahnn J, et al. Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis. Science Signaling. 7: ra54. PMID 24917591 DOI: 10.1126/Scisignal.2004983 |
0.442 |
|
| 2014 |
Kim KD, Srikanth S, Tan YV, Yee MK, Jew M, Damoiseaux R, Jung ME, Shimizu S, An DS, Ribalet B, Waschek JA, Gwack Y. Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 192: 110-22. PMID 24307733 DOI: 10.4049/Jimmunol.1302586 |
0.54 |
|
| 2013 |
Srikanth S, Gwack Y. Molecular regulation of the pore component of CRAC channels, Orai1. Current Topics in Membranes. 71: 181-207. PMID 23890116 DOI: 10.1016/B978-0-12-407870-3.00008-1 |
0.668 |
|
| 2013 |
Srikanth S, Gwack Y. Orai1-NFAT signalling pathway triggered by T cell receptor stimulation. Molecules and Cells. 35: 182-94. PMID 23483280 DOI: 10.1007/S10059-013-0073-2 |
0.63 |
|
| 2013 |
Srikanth S, Ribalet B, Gwack Y. Regulation of CRAC channels by protein interactions and post-translational modification. Channels (Austin, Tex.). 7: 354-63. PMID 23454861 DOI: 10.4161/Chan.23801 |
0.656 |
|
| 2013 |
Srikanth S, Gwack Y. Measurement of intracellular Ca2+ concentration in single cells using ratiometric calcium dyes. Methods in Molecular Biology (Clifton, N.J.). 963: 3-14. PMID 23296601 DOI: 10.1007/978-1-62703-230-8_1 |
0.647 |
|
| 2012 |
Srikanth S, Gwack Y. Orai1, STIM1, and their associating partners. The Journal of Physiology. 590: 4169-77. PMID 22586216 DOI: 10.1113/Jphysiol.2012.231522 |
0.623 |
|
| 2012 |
Srikanth S, Jew M, Kim KD, Yee MK, Abramson J, Gwack Y. Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1). Proceedings of the National Academy of Sciences of the United States of America. 109: 8682-7. PMID 22586105 DOI: 10.1073/Pnas.1200667109 |
0.592 |
|
| 2011 |
Kim KD, Srikanth S, Yee MK, Mock DC, Lawson GW, Gwack Y. ORAI1 deficiency impairs activated T cell death and enhances T cell survival. Journal of Immunology (Baltimore, Md. : 1950). 187: 3620-30. PMID 21873530 DOI: 10.4049/Jimmunol.1100847 |
0.541 |
|
| 2011 |
Srikanth S, Yee MK, Gwack Y, Ribalet B. The third transmembrane segment of orai1 protein modulates Ca2+ release-activated Ca2+ (CRAC) channel gating and permeation properties. The Journal of Biological Chemistry. 286: 35318-28. PMID 21865174 DOI: 10.1074/Jbc.M111.265884 |
0.611 |
|
| 2011 |
Newton RH, Leverrier S, Srikanth S, Gwack Y, Cahalan MD, Walsh CM. Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation. Journal of Immunology (Baltimore, Md. : 1950). 186: 940-50. PMID 21148796 DOI: 10.4049/Jimmunol.1000942 |
0.552 |
|
| 2010 |
Srikanth S, Jung HJ, Kim KD, Souda P, Whitelegge J, Gwack Y. A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. Nature Cell Biology. 12: 436-46. PMID 20418871 DOI: 10.1038/Ncb2045 |
0.496 |
|
| 2010 |
Srikanth S, Jung HJ, Ribalet B, Gwack Y. The intracellular loop of Orai1 plays a central role in fast inactivation of Ca2+ release-activated Ca2+ channels. The Journal of Biological Chemistry. 285: 5066-75. PMID 20007711 DOI: 10.1074/Jbc.M109.072736 |
0.64 |
|
| 2010 |
Srikanth S, Jung H, Ribalet B, Gwack Y. The Intracellular Loop of Orai1 Plays a Central Role in Fast Inactivation of CRAC Channels Biophysical Journal. 98: 540a. DOI: 10.1016/J.Bpj.2009.12.2929 |
0.618 |
|
| 2008 |
Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, Yamashita M, Gelinas C, Neems DS, Sasaki Y, Feske S, Prakriya M, Rajewsky K, Rao A. Hair loss and defective T- and B-cell function in mice lacking ORAI1. Molecular and Cellular Biology. 28: 5209-22. PMID 18591248 DOI: 10.1128/Mcb.00360-08 |
0.453 |
|
| 2008 |
Barr VA, Bernot KM, Srikanth S, Gwack Y, Balagopalan L, Regan CK, Helman DJ, Sommers CL, Oh-Hora M, Rao A, Samelson LE. Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps. Molecular Biology of the Cell. 19: 2802-17. PMID 18448669 DOI: 10.1091/Mbc.E08-02-0146 |
0.497 |
|
| 2007 |
Gwack Y, Feske S, Srikanth S, Hogan PG, Rao A. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium. 42: 145-56. PMID 17572487 DOI: 10.1016/J.Ceca.2007.03.007 |
0.625 |
|
| 2007 |
Gwack Y, Srikanth S, Feske S, Cruz-Guilloty F, Oh-hora M, Neems DS, Hogan PG, Rao A. Biochemical and functional characterization of Orai proteins. The Journal of Biological Chemistry. 282: 16232-43. PMID 17293345 DOI: 10.1074/Jbc.M609630200 |
0.644 |
|
| 2007 |
Ong HL, Cheng KT, Liu X, Bandyopadhyay BC, Paria BC, Soboloff J, Pani B, Gwack Y, Srikanth S, Singh BB, Gill DL, Gill D, Ambudkar IS. Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. The Journal of Biological Chemistry. 282: 9105-16. PMID 17224452 DOI: 10.1074/Jbc.M608942200 |
0.553 |
|
| 2006 |
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A, Hogan PG. Orai1 is an essential pore subunit of the CRAC channel. Nature. 443: 230-3. PMID 16921383 DOI: 10.1038/Nature05122 |
0.647 |
|
| 2006 |
Banerjee S, Joshi R, Venkiteswaran G, Agrawal N, Srikanth S, Alam F, Hasan G. Compensation of inositol 1,4,5-trisphosphate receptor function by altering sarco-endoplasmic reticulum calcium ATPase activity in the Drosophila flight circuit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8278-88. PMID 16899722 DOI: 10.1523/Jneurosci.1231-06.2006 |
0.538 |
|
| 2006 |
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature. 441: 179-85. PMID 16582901 DOI: 10.1038/Nature04702 |
0.623 |
|
| 2006 |
Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A. A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT. Nature. 441: 646-50. PMID 16511445 DOI: 10.1038/Nature04631 |
0.455 |
|
| 2006 |
Srikanth S, Banerjee S, Hasan G. Ectopic expression of a Drosophila InsP(3)R channel mutant has dominant-negative effects in vivo. Cell Calcium. 39: 187-96. PMID 16325255 DOI: 10.1016/J.Ceca.2005.10.013 |
0.761 |
|
| 2004 |
Srikanth S, Wang Z, Hasan G, Bezprozvanny I. Functional properties of a pore mutant in the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor. Febs Letters. 575: 95-8. PMID 15388340 DOI: 10.1016/J.Febslet.2004.08.042 |
0.677 |
|
| 2004 |
Srikanth S, Wang Z, Tu H, Nair S, Mathew MK, Hasan G, Bezprozvanny I. Functional properties of the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor mutants. Biophysical Journal. 86: 3634-46. PMID 15189860 DOI: 10.1529/Biophysj.104.040121 |
0.744 |
|
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