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David D. Eisenstat, M.D., M.A., F.R.C.P.C - Publications

Affiliations: 
Pediatrics and Medical Genetics University of Alberta, Edmonton, Alberta, Canada 
Area:
CNS germinoma, GBM, BNIP3
Website:
http://www.braintumorfunders.org/eisenstat.php
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Burnett M, Abuetabh Y, Wronski A, Shen F, Persad S, Leng R, Eisenstat D, Sergi C. Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells. Journal of Cancer. 11: 5007-5023. PMID 32742448 DOI: 10.7150/Jca.46464  0.336
2020 Fonseca A, Afzal S, Bowes L, Crooks B, Larouche V, Jabado N, Perreault S, Johnston DL, Zelcer S, Fleming A, Scheinemann K, Silva M, Vanan MI, Mpofu C, Wilson B, ... Eisenstat DD, et al. Pontine gliomas a 10-year population-based study: a report from The Canadian Paediatric Brain Tumour Consortium (CPBTC). Journal of Neuro-Oncology. PMID 32632896 DOI: 10.1007/S11060-020-03568-8  0.308
2019 Japoni S, Song X, Leng R, Eisenstat D. BIOL-04. DISTAL-LESS/DLX2 HOMEOBOX GENE REGULATION OF CHEMOKINE RECEPTOR CXCR4 - ROLE IN MIGRATION IN FOREBRAIN DEVELOPMENT AND CNS TUMORS Neuro-Oncology. 21: ii66-ii67. DOI: 10.1093/Neuonc/Noz036.017  0.312
2018 Singh A, Azad M, Shymko MD, Henson ES, Katyal S, Eisenstat DD, Gibson SB. The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation. Plos One. 13: e0204792. PMID 30307949 DOI: 10.1371/Journal.Pone.0204792  0.302
2018 Nevin M, Song X, Becher O, Underhill DA, Godbout R, Eisenstat D. PDTM-12. DLX2 TRANSCRIPTIONAL REGULATION OF CENTRAL NERVOUS SYSTEM CELL FATE RELEVANCE TO PEDIATRIC DIFFUSE MIDLINE GLIOMAS WITH HISTONE 3 MUTATIONS Neuro-Oncology. 20: vi206-vi206. DOI: 10.1093/Neuonc/Noy148.854  0.303
2018 Zapotocky M, Ryall S, Fukuoka K, Stucklin AG, Bennett J, Sumerauer D, Pavelka Z, Cruz O, Solano P, Garre ML, Hauser P, Frappaz D, Hansford J, Amayiri N, Morse H, ... ... Eisenstat D, et al. Lgg-59. Remarkable Objective Response And Favorable Survival For Braf-V600E Childhood Low-Grade Gliomas To Braf Inhibitors Compared Conventional Chemotherapy Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.399  0.309
2018 Nevin M, Song X, Japoni S, Zagozewski J, Jiang Q, Becher O, Godbout R, Underhill D, Eisenstat D. 09 Could DLX2 regulation of neural progenitor cell fate contribute to differentiation of diffuse intrinsic pontine glioma (DIPG)? Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S16-S16. DOI: 10.1017/Cjn.2018.305  0.331
2018 Michaiel G, Strother D, Gottardo N, Bartels U, Coltin H, Eisenstat DD, Hukin J, Johnston DL, Wilson B, Zelcer S, Hansford JR, Wells O, AbdelBaki MS, Abu-Arja MH, Cole KA, et al. 31 Intracranial growing teratoma syndrome (IGTS): An international retrospective study Canadian Journal of Neurological Sciences. 45. DOI: 10.1017/Cjn.2018.295  0.358
2018 Jiang Q, Zagozewski J, Nozza P, Wilson B, Van Landeghem F, Eisenstat D. 60 Are gangliogliomas in children and adults disorders of nervous system development? Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 45: S10-S10. DOI: 10.1017/Cjn.2018.288  0.33
2017 Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, ... ... Eisenstat D, et al. Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta Neuropathologica. PMID 28733933 DOI: 10.1007/S00401-017-1752-4  0.351
2017 Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M, Krishnatry R, Guerreiro Stucklin A, Zhukova N, Arnoldo A, Ryall S, Ling C, McKeown T, Loukides J, Cruz O, de Torres C, ... ... Eisenstat D, et al. Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016718726. PMID 28727518 DOI: 10.1200/Jco.2016.71.8726  0.362
2017 Story E, Johnston DL, Bartels U, Carret AS, Crooks B, Eisenstat DD, Fryer C, Lafay-Cousin L, Larouche V, Wilson B, Zelcer S, Silva M, Brossard J, Bouffet E, Keene DL. Embryonal tumors in Canadian children less than 36 months of age: results from the Canadian Pediatric Brain Tumor Consortium (CPBTC). Journal of Neuro-Oncology. PMID 28508928 DOI: 10.1007/S11060-017-2468-Y  0.344
2017 Vanan MI, Underhill DA, Eisenstat DD. Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28233220 DOI: 10.1007/S13311-017-0514-2  0.336
2017 Fossey M, Li H, Afzal S, Carret AS, Eisenstat DD, Fleming A, Hukin J, Hawkins C, Jabado N, Johnston D, Brown T, Larouche V, Scheinemann K, Strother D, Wilson B, et al. Atypical teratoid rhabdoid tumor in the first year of life: the Canadian ATRT registry experience and review of the literature. Journal of Neuro-Oncology. PMID 28102486 DOI: 10.1007/S11060-016-2353-0  0.36
2016 Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, ... ... Eisenstat DD, et al. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Cancer Cell. 30: 891-908. PMID 27960086 DOI: 10.1016/J.Ccell.2016.11.003  0.342
2016 Lassaletta A, Scheinemann K, Zelcer SM, Hukin J, Wilson BA, Jabado N, Carret AS, Lafay-Cousin L, Larouche V, Hawkins CE, Pond GR, Poskitt K, Keene D, Johnston DL, Eisenstat DD, et al. Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27573663 DOI: 10.1200/Jco.2016.68.1585  0.376
2016 Eisenstat D, Landeghem Fv. Mpth-49. Is Ganglioglioma A Cns Tumor With Arrested Development? Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.484  0.314
2016 Lassaletta A, Mistry M, Arnaldo A, Ryall S, Guerreiro-Stucklin A, Krishnatry R, Ling C, Honnorat M, Zhukova N, Zapotocky M, McKeown T, Ramaswamy V, Bartels U, Huang A, Jabado N, ... ... Eisenstat D, et al. Lg-46Inferior Outcome And Poor Response To Conventional Therapies In Pediatric Low-Grade Gliomas Harboring The Braf V600E Mutation. Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now075.46  0.304
2016 Baadjes B, Cheng S, Steinbok P, Potts J, Goddard K, Ailon T, Tabori U, Carret A, McNeely D, Eisenstat D, Wilson B, Johnston D, Zelcer S, Scheinemann K, Dunham C, et al. EPN-37PAEDIATRIC SPINAL EPENDYMOMA IN CANADA: A MULTICENTRE RETROSPECTIVE STUDY Neuro-Oncology. 18: iii39.1-iii39. DOI: 10.1093/Neuonc/Now070.36  0.318
2016 Jiang Q, Zagozewski J, Nozza P, Wilson B, Van Landeghem F, Eisenstat D. PS1 - 218 Characterization of Ganglioglioma as a Neurodevelopmental Disorder: A Cast of Arrested Development? Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 43: S12-S12. DOI: 10.1017/Cjn.2016.363  0.342
2015 Steinbok P, Gopalakrishnan CV, Hengel AR, Vitali AM, Poskitt K, Hawkins C, Drake J, Lamberti-Pasculli M, Ajani O, Hader W, Mehta V, McNeely PD, McDonald PJ, Ranger A, Vassilyadi M, ... ... Eisenstat DD, et al. Pediatric thalamic tumors in the MRI era: a Canadian perspective. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 26597682 DOI: 10.1007/S00381-015-2968-Z  0.346
2015 Vanan MI, Eisenstat DD. DIPG in Children - What Can We Learn from the Past? Frontiers in Oncology. 5: 237. PMID 26557503 DOI: 10.3389/Fonc.2015.00237  0.394
2015 Chen Y, Henson ES, Xiao W, Shome E, Azad MB, Burton TR, Queau M, Sathya A, Eisenstat DD, Gibson SB. Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells. Cancer Biology & Therapy. 0. PMID 26467103 DOI: 10.1080/15384047.2015.1095399  0.329
2015 Johnston DL, Keene D, Bartels U, Carret AS, Crooks B, Eisenstat DD, Fryer C, Lafay-Cousin L, Larouche V, Moghrabi A, Wilson B, Zelcer S, Silva M, Bouffet E. Low grade astrocytoma in children under the age of three years: a report from the Canadian pediatric brain tumour consortium. Journal of Neuro-Oncology. 124: 95-100. PMID 25968346 DOI: 10.1007/S11060-015-1806-1  0.38
2015 Li AM, Dunham C, Tabori U, Carret AS, McNeely PD, Johnston D, Lafay-Cousin L, Wilson B, Eisenstat DD, Jabado N, Zelcer S, Silva M, Scheinemann K, Fryer C, Hendson G, et al. EZH2 expression is a prognostic factor in childhood intracranial ependymoma: a Canadian Pediatric Brain Tumor Consortium study. Cancer. 121: 1499-507. PMID 25586788 DOI: 10.1002/Cncr.29198  0.392
2015 Eisenstat DD, Pollack IF, Demers A, Sapp MV, Lambert P, Weisfeld-Adams JD, Burger PC, Gilles F, Davis RL, Packer R, Boyett JM, Finlay JL. Impact of tumor location and pathological discordance on survival of children with midline high-grade gliomas treated on Children's Cancer Group high-grade glioma study CCG-945. Journal of Neuro-Oncology. 121: 573-81. PMID 25431150 DOI: 10.1007/S11060-014-1669-X  0.387
2015 Ailon T, Dunham C, Carret AS, Tabori U, Mcneely PD, Zelcer S, Wilson B, Lafay-Cousin L, Johnston D, Eisenstat DD, Silva M, Jabado N, Goddard KJ, Fryer C, Hendson G, et al. The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 31: 57-65. PMID 25391979 DOI: 10.1007/S00381-014-2575-4  0.319
2015 Reardon DA, Nabors LB, Mason WP, Perry JR, Shapiro W, Kavan P, Mathieu D, Phuphanich S, Cseh A, Fu Y, Cong J, Wind S, Eisenstat DD. Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma. Neuro-Oncology. 17: 430-9. PMID 25140039 DOI: 10.1093/Neuonc/Nou160  0.349
2015 Chen Y, Henson E, Shome E, Xiao W, Eisenstat D, Gibson S. CBIO-10Bcl-2 FAMILY MEMBER Mcl-1 EXPRESSION IS REDUCED UNDER HYPOXIA BY THE E3 LIGASE FBW7 CONTRIBUTING TO BNIP3 INDUCED CELL DEATH IN GLIOMA CELLS Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov209.10  0.348
2015 Zagozewski J, Japoni S, Jiang Q, Landeghem Fv, Nozza P, Raso A, Eisenstat D. Bi-03Dlx Homeobox Genes Regulate Neuronal Vs Oligodendroglial Cell Fate Decisions: Potential Relevance To Pediatric Glioneuronal Tumors And High Grade Gliomas Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.9  0.35
2014 Vanan MI, Eisenstat DD. Management of high-grade gliomas in the pediatric patient: Past, present, and future. Neuro-Oncology Practice. 1: 145-157. PMID 26034626 DOI: 10.1093/Nop/Npu022  0.411
2014 Purdy E, Johnston DL, Bartels U, Fryer C, Carret AS, Crooks B, Eisenstat DD, Lafay-Cousin L, Larouche V, Wilson B, Zelcer S, Silva M, Bouffet E, Keene D, Strother DR. Ependymoma in children under the age of 3 years: a report from the Canadian Pediatric Brain Tumour Consortium. Journal of Neuro-Oncology. 117: 359-64. PMID 24532240 DOI: 10.1007/S11060-014-1396-3  0.38
2014 Eisenstat DD, Zagozewski J, Ziegler K, Japoni S, Jiang Q, Underhill DA. Transcriptional Regulation Of Oligodendroglial Cell Fate By Dlx Homeobox Genes: Potential Relevance To Histone H3.3 Mutations In Pediatric High Grade Glioma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou208.10  0.335
2013 Osorio DS, Finlay JL, Dhall G, Goldman S, Eisenstat D, Brown RJ. Feasibility of dasatinib in children and adolescents with new or recurrent central nervous system germinoma. Pediatric Blood & Cancer. 60: E100-2. PMID 23754592 DOI: 10.1002/Pbc.24567  0.35
2013 Burton TR, Henson ES, Azad MB, Brown M, Eisenstat DD, Gibson SB. BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas. Cell Death & Disease. 4: e587. PMID 23579274 DOI: 10.1038/Cddis.2013.100  0.362
2012 Lafay-Cousin L, Hawkins C, Carret AS, Johnston D, Zelcer S, Wilson B, Jabado N, Scheinemann K, Eisenstat D, Fryer C, Fleming A, Mpofu C, Larouche V, Strother D, Bouffet E, et al. Central nervous system atypical teratoid rhabdoid tumours: the Canadian Paediatric Brain Tumour Consortium experience. European Journal of Cancer (Oxford, England : 1990). 48: 353-9. PMID 22023887 DOI: 10.1016/J.Ejca.2011.09.005  0.353
2012 Pitz MW, Eisenhauer EA, MacNeil MV, Thiessen B, Macdonald DR, Easaw JC, Eisenstat DD, Kakumanu AS, Squire J, Tsao MS, Kamel-Reid S, Tassignon A, Hausman DF, Mason WP. Phase II study of PX-866 in recurrent glioblastoma. Journal of Clinical Oncology. 30: 2051-2051. DOI: 10.1200/Jco.2012.30.15_Suppl.2051  0.305
2011 Eisenstat DD, Nabors LB, Mason WP, Perry JR, Shapiro WR, Kavan P, Phuphanich S, Fu Y, Cong XJ, Shahidi M, Reardon DA. A phase II study of daily afatinib (BIBW 2992) with or without temozolomide (21/28 days) in the treatment of patients with recurrent glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2010. PMID 28023857 DOI: 10.1200/Jco.2011.29.15_Suppl.2010  0.305
2011 Easaw JC, Mason WP, Perry J, Laperrière N, Eisenstat DD, Del Maestro R, Bélanger K, Fulton D, Macdonald D. Canadian recommendations for the treatment of recurrent or progressive glioblastoma multiforme. Current Oncology (Toronto, Ont.). 18: e126-36. PMID 21655151 DOI: 10.3747/Co.V18I3.755  0.321
2011 Lafay-Cousin L, Keene D, Carret AS, Fryer C, Brossard J, Crooks B, Eisenstat D, Johnston D, Larouche V, Silva M, Wilson B, Zelcer S, Bartels U, Bouffet E. Choroid plexus tumors in children less than 36 months: The Canadian Pediatric Brain Tumor Consortium (CPBTC) experience Child's Nervous System. 27: 259-264. PMID 20809071 DOI: 10.1007/S00381-010-1269-9  0.353
2011 Bartels U, Baruchel S, Carret AS, Crooks B, Hukin J, Johnston D, Silva M, Strother D, Wilson B, Zelcer S, Eisenstat D, Sung L, Bouffet E. The use and effectiveness of temozolomide in children with central nervous system tumours: A survey from the Canadian paediatric brain tumour consortium Current Oncology. 18: e19-e24. DOI: 10.3747/Co.V18I1.675  0.346
2010 Sharp JR, Bouffet E, Stempak D, Gammon J, Stephens D, Johnston DL, Eisenstat D, Hukin J, Samson Y, Bartels U, Tabori U, Huang A, Baruchel S. A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma European Journal of Cancer. 46: 3271-3279. PMID 20656474 DOI: 10.1016/J.Ejca.2010.06.115  0.336
2010 Perry JR, Bélanger K, Mason WP, Fulton D, Kavan P, Easaw J, Shields C, Kirby S, Macdonald DR, Eisenstat DD, Thiessen B, Forsyth P, Pouliot JF. Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2051-7. PMID 20308655 DOI: 10.1200/Jco.2009.26.5520  0.333
2010 Johnston DL, Keene D, Bartels U, Carret AS, Crooks B, Eisenstat D, Fryer C, Lafay-Cousin L, Larouche V, Moghrabi A, Wilson B, Zelcer S, Silva M, Brossard J, Bouffet E. Patterns of enrollment of infants with central nervous system tumours on cooperative group studies: A report from the Canadian Pediatric Brain Tumour Consortium Journal of Neuro-Oncology. 99: 243-249. PMID 20135195 DOI: 10.1007/S11060-010-0123-Y  0.375
2009 Burton TR, Eisenstat DD, Gibson SB. BNIP3 (Bcl-2 19 kDa interacting protein) acts as transcriptional repressor of apoptosis-inducing factor expression preventing cell death in human malignant gliomas. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4189-99. PMID 19339613 DOI: 10.1523/Jneurosci.5747-08.2009  0.347
2009 Johnston DL, Keene D, Bartels U, Carret AS, Crooks B, Eisenstat DD, Fryer C, Lafay-Cousin L, Larouche V, Moghrabi A, Wilson B, Zelcer S, Silva M, Brossard J, Bouffet E. Medulloblastoma in children under the age of three years: a retrospective Canadian review. Journal of Neuro-Oncology. 94: 51-6. PMID 19184579 DOI: 10.1007/S11060-009-9799-2  0.352
2008 Johnston DL, Keene DL, Lafay-Cousin L, Steinbok P, Sung L, Carret AS, Crooks B, Strother D, Wilson B, Odame I, Eisenstat DD, Mpofu C, Zelcer S, Huang A, Bouffet E. Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium report. Journal of Neuro-Oncology. 86: 101-8. PMID 17619825 DOI: 10.1007/S11060-007-9440-1  0.398
2007 Keene D, Johnston D, Strother D, Fryer C, Carret AS, Crooks B, Eisenstat D, Moghrabi A, Wilson B, Brossard J, Mpofu C, Odame I, Zelcer S, Silva M, Samson Y, et al. Epidemiological survey of central nervous system germ cell tumors in Canadian children Journal of Neuro-Oncology. 82: 289-295. PMID 17120159 DOI: 10.1007/S11060-006-9282-2  0.364
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