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Digvijay Singh - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Biophysics, optics, single-molecule, fluorescence, Electron microscopy, Electron tomography, Molecular Biology, Biochemistry, CRISPR
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, et al. The molecular architecture of the nuclear basket. Cell. PMID 39127037 DOI: 10.1016/j.cell.2024.07.020  0.5
2024 Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, et al. The Molecular Architecture of the Nuclear Basket. Biorxiv : the Preprint Server For Biology. PMID 38586009 DOI: 10.1101/2024.03.27.587068  0.5
2024 Raveh B, Eliasian R, Rashkovits S, Russel D, Hayama R, Sparks SE, Singh D, Lim R, Villa E, Rout MP, Cowburn D, Sali A. Integrative spatiotemporal map of nucleocytoplasmic transport. Biorxiv : the Preprint Server For Biology. PMID 38260487 DOI: 10.1101/2023.12.31.573409  0.461
2021 Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, et al. Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell. PMID 34982960 DOI: 10.1016/j.cell.2021.12.015  0.477
2021 Dai L, Singh D, Lu S, Kottadiel VI, Vafabakhsh R, Mahalingam M, Chemla YR, Ha T, Rao VB. A viral genome packaging ring-ATPase is a flexibly coordinated pentamer. Nature Communications. 12: 6548. PMID 34772936 DOI: 10.1038/s41467-021-26800-z  0.403
2021 Poddar A, Azam MS, Kayikcioglu T, Bobrovskyy M, Zhang J, Ma X, Labhsetwar P, Fei J, Singh D, Luthey-Schulten Z, Vanderpool CK, Ha T. Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA. Nature Communications. 12: 874. PMID 33558533 DOI: 10.1038/s41467-021-21144-0  0.464
2021 Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR, Villa E, Cleveland DW, Corbett KD. The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nature Communications. 12: 502. PMID 33479198 DOI: 10.1038/s41467-020-20768-y  0.506
2021 Wang Y, Mallon J, Wang H, Singh D, Hyun Jo M, Hua B, Bailey S, Ha T. Real-time observation of Cas9 postcatalytic domain motions. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33443184 DOI: 10.1073/pnas.2010650118  0.479
2020 Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, Toprani D, Beccari MS, Yates JR, Da Cruz S, Newby JM, Lafarga M, Gladfelter AS, Villa E, Cleveland DW. HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science (New York, N.Y.). PMID 33335017 DOI: 10.1126/science.abb4309  0.497
2020 Lu S, Ye Q, Singh D, Villa E, Cleveland DW, Corbett KD. The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Biorxiv : the Preprint Server For Biology. PMID 32766587 DOI: 10.1101/2020.07.30.228023  0.513
2020 Wagner FR, Watanabe R, Schampers R, Singh D, Persoon H, Schaffer M, Fruhstorfer P, Plitzko J, Villa E. Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography. Nature Protocols. PMID 32405053 DOI: 10.1038/S41596-020-0320-X  0.436
2019 Okafor IC, Singh D, Wang Y, Jung M, Wang H, Mallon J, Bailey S, Lee JK, Ha T. Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding. Nucleic Acids Research. PMID 31713616 DOI: 10.1093/Nar/Gkz1058  0.539
2018 Singh D, Mallon J, Poddar A, Wang Y, Tippana R, Yang O, Bailey S, Ha T. Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a). Proceedings of the National Academy of Sciences of the United States of America. PMID 29735714 DOI: 10.1073/Pnas.1718686115  0.571
2018 Singh D, Wang Y, Mallon J, Yang O, Fei J, Poddar A, Ceylan D, Bailey S, Ha T. Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis. Nature Structural & Molecular Biology. 25: 347-354. PMID 29622787 DOI: 10.1038/S41594-018-0051-7  0.539
2018 Hua B, Wang Y, Park S, Han KY, Singh D, Kim JH, Cheng W, Ha T. Single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays. Biochemistry. PMID 29457977 DOI: 10.1021/Acs.Biochem.7B01293  0.531
2018 Singh D, Ha T. Understanding the molecular mechanisms of CRISPR toolbox using single molecule approaches. Acs Chemical Biology. PMID 29394047 DOI: 10.1021/Acschembio.7B00905  0.486
2018 Wang Y, Singh D, Mallon J, Hua B, Bailey S, Ha T. Simultaneous Real-Time Observation of DNA Unwinding and Nuclease Domain Activation in Cas9-RNA-DNA Complex via Three-Color Single Molecule FRET Biophysical Journal. 114: 572a. DOI: 10.1016/J.Bpj.2017.11.3127  0.552
2017 Singh D, Mallon J, Tipanna R, Poddar A, Yang O, Bailey S, Ha T. Investigation of DNA Binding, Nucleolysis and Product Release Specificity of RNA Guided Endonuclease CRISPR-Cpf1 Family Reveals Important Differences from Cas9-RNA Biophysical Journal. 112: 472a. DOI: 10.1016/J.Bpj.2016.11.2531  0.536
2016 Singh D, Sternberg SH, Fei J, Doudna JA, Ha T. Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9. Nature Communications. 7: 12778. PMID 27624851 DOI: 10.1038/Ncomms12778  0.583
2016 Dai L, Singh D, Vafabakhsh R, Mahalingam M, Kottadiel V, Chemla Y, Ha T, Rao VB. Mechanism of Coordination of the Bacteriophage T4 DNA Packaging Motor Analyzed by Real-Time Single Molecule Fluorescence Assay Biophysical Journal. 110: 46a. DOI: 10.1016/J.Bpj.2015.11.316  0.481
2015 Fei J, Singh D, Zhang Q, Park S, Balasubramanian D, Golding I, Vanderpool CK, Ha T. RNA biochemistry. Determination of in vivo target search kinetics of regulatory noncoding RNA. Science (New York, N.Y.). 347: 1371-4. PMID 25792329 DOI: 10.1126/Science.1258849  0.535
2015 Singh D, Sternberg SH, Fei J, Doudna JA, Ha T. Real-Time Observation of DNA Recognition by the RNA-Guided Endonuclease Cas9 using Single-Molecule FRET Biophysical Journal. 108: 26a. DOI: 10.1016/J.Bpj.2014.11.169  0.589
2014 Hua B, Han KY, Zhou R, Kim H, Shi X, Abeysirigunawardena SC, Jain A, Singh D, Aggarwal V, Woodson SA, Ha T. An improved surface passivation method for single-molecule studies. Nature Methods. 11: 1233-6. PMID 25306544 DOI: 10.1038/Nmeth.3143  0.652
2014 Fei J, Singh D, Zhang Q, Park S, Golding I, Vanderpool CK, Ha T. Watching Gene Regulation by Small RNA in Bacteria with Super-Resolution Imaging Biophysical Journal. 106: 434a. DOI: 10.1016/J.Bpj.2013.11.2447  0.535
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