Henry F. McFarland, MD - Publications

Affiliations: 
NINDS / Neuroimmunology Branch National Institutes of Health, Bethesda, MD 
Area:
multiple sclerosis, neuroimmunology,MR imaging

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Borges IT, Shea CD, Ohayon J, Jones BC, Stone RD, Ostuni J, Shiee N, McFarland H, Bielekova B, Reich DS. The effect of daclizumab on brain atrophy in relapsing-remitting multiple sclerosis. Multiple Sclerosis and Related Disorders. 2: 133-140. PMID 23580931 DOI: 10.1016/j.msard.2012.10.002  0.6
2013 Yuen TJ, Johnson KR, Miron VE, Zhao C, Quandt J, Harrisingh MC, Swire M, Williams A, McFarland HF, Franklin RJ, Ffrench-Constant C. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain : a Journal of Neurology. 136: 1035-47. PMID 23518706 DOI: 10.1093/brain/awt024  0.6
2013 Ohayon J, Oh U, Richert N, Martin J, Vortmeyer A, McFarland H, Bielekova B. CNS vasculitis in a patient with MS on daclizumab monotherapy. Neurology. 80: 453-7. PMID 23303850 DOI: 10.1212/WNL.0b013e31827f0f42  0.6
2012 Quandt JA, Huh J, Baig M, Yao K, Ito N, Bryant M, Kawamura K, Pinilla C, McFarland HF, Martin R, Ito K. Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 189: 2897-908. PMID 22888134 DOI: 10.4049/jimmunol.1103087  0.6
2012 Bielekova B, McFarland H. Comment on "interleukin-2/Interleukin-2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation" Annals of Neurology. 71: 148-149. PMID 22275261 DOI: 10.1002/ana.22547  0.6
2011 Bielekova B, Richert N, Herman ML, Ohayon J, Waldmann TA, McFarland H, Martin R, Blevins G. Intrathecal effects of daclizumab treatment of multiple sclerosis Neurology. 77: 1877-1886. PMID 22076546 DOI: 10.1212/WNL.0b013e318239f7ef  0.6
2011 McFarland H. The importance of clinical trials in unraveling the mysteries of multiple sclerosis Journal of Neuroimmunology. 231: 3-6. PMID 21300410 DOI: 10.1016/j.jneuroim.2010.12.010  0.6
2011 Bomboi G, Ikonomidou VN, Pellegrini S, Stern SK, Gallo A, Auh S, Evangelou IE, Agarwal J, Pellicano C, Ohayon JM, Cantor FK, Ehrmantraut M, McFarland HF, Kane RL, Bagnato F. Quality and quantity of diffuse and focal white matter disease and cognitive disability of patients with multiple sclerosis. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 21: e57-63. PMID 20626570 DOI: 10.1111/j.1552-6569.2010.00488.x  0.6
2011 Reingold SC, McFarland HF, John Petkau A. The growing need for alternative clinical trial designs for multiple sclerosis Multiple Sclerosis Therapeutics, Fourth Edition. 253-260. DOI: 10.1017/CBO9781139023986.024  0.6
2010 Bagnato F, Salman Z, Kane R, Auh S, Cantor FK, Ehrmantraut M, Gallo A, Ikonomidou VN, Ohayon J, Pellicano C, Stern SK, McFarland HF. T1 cortical hypointensities and their association with cognitive disability in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 1203-12. PMID 20699284 DOI: 10.1177/1352458510377223  0.6
2010 Polman CH, Bertolotto A, Deisenhammer F, Giovannoni G, Hartung HP, Hemmer B, Killestein J, McFarland HF, Oger J, Pachner AR, Petkau J, Reder AT, Reingold SC, Schellekens H, Sørensen PS. Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis. The Lancet. Neurology. 9: 740-50. PMID 20610349 DOI: 10.1016/S1474-4422(10)70103-4  0.6
2010 Pellicano C, Gallo A, Li X, Ikonomidou VN, Evangelou IE, Ohayon JM, Stern SK, Ehrmantraut M, Cantor F, McFarland HF, Bagnato F. Relationship of cortical atrophy to fatigue in patients with multiple sclerosis. Archives of Neurology. 67: 447-53. PMID 20385911 DOI: 10.1001/archneurol.2010.48  0.6
2010 Davis M, Auh S, Riva M, Richert ND, Frank JA, McFarland HF, Bagnato F. Ring and nodular multiple sclerosis lesions: a retrospective natural history study. Neurology. 74: 851-6. PMID 20211910 DOI: 10.1212/WNL.0b013e3181d31df5  0.6
2010 McFarland HF. Examination of the role of MRI in multiple sclerosis: a problem orientated approach. Results and Problems in Cell Differentiation. 51: 287-301. PMID 19960380 DOI: 10.1007/400_2009_33  0.6
2009 McFarland HF. Examination of the role of magnetic resonance imaging in multiple sclerosis: A problem-orientated approach. Annals of Indian Academy of Neurology. 12: 254-63. PMID 20182573 DOI: 10.4103/0972-2327.58284  0.6
2009 Bielekova B, Richert N, Howard T, Packer AN, Blevins G, Ohayon J, McFarland HF, Stürzebecher CS, Martin R. Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood--brain barrier disruption in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 15: 1206-14. PMID 19776093 DOI: 10.1177/1352458509345903  0.6
2009 Bagnato F, Yao B, Cantor F, Merkle H, Condon E, Montequin M, Moore S, Quezado M, Tkaczyk D, McFarland H. Multisequence-imaging protocols to detect cortical lesions of patients with multiple sclerosis: observations from a post-mortem 3 Tesla imaging study. Journal of the Neurological Sciences. 282: 80-5. PMID 19394970 DOI: 10.1016/j.jns.2009.03.021  0.6
2009 Tovar-Moll F, Evangelou IE, Chiu AW, Richert ND, Ostuni JL, Ohayon JM, Auh S, Ehrmantraut M, Talagala SL, McFarland HF, Bagnato F. Thalamic involvement and its impact on clinical disability in patients with multiple sclerosis: a diffusion tensor imaging study at 3T. Ajnr. American Journal of Neuroradiology. 30: 1380-6. PMID 19369608 DOI: 10.3174/ajnr.A1564  0.6
2009 Bielekova B, Howard T, Packer AN, Richert N, Blevins G, Ohayon J, Waldmann TA, McFarland HF, Martin R. Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis. Archives of Neurology. 66: 483-9. PMID 19364933 DOI: 10.1001/archneurol.2009.50  0.6
2009 Oh U, Blevins G, Griffith C, Richert N, Maric D, Lee CR, McFarland H, Jacobson S. Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis. Archives of Neurology. 66: 471-9. PMID 19364932 DOI: 10.1001/archneurol.2009.16  0.6
2009 McFarland HF. Alemtuzumab versus interferon beta-1a: implications for pathology and trial design. The Lancet. Neurology. 8: 26-8. PMID 19081510 DOI: 10.1016/S1474-4422(08)70280-1  0.6
2009 Chiu AW, Richert N, Ehrmantraut M, Ohayon J, Gupta S, Bomboi G, Gaindh D, Cantor FK, Frank JA, McFarland HF, Bagnato F. Heterogeneity in response to interferon beta in patients with multiple sclerosis: a 3-year monthly imaging study. Archives of Neurology. 66: 39-43. PMID 19001157 DOI: 10.1001/archneur.66.1.noc80047  0.6
2008 Gaindh D, Jeffries N, Ohayon J, Richert ND, Pellicano C, Frank JA, McFarland H, Bagnato F. The effect of interferon beta-1b on size of short-lived enhancing lesions in patients with multiple sclerosis. Expert Opinion On Biological Therapy. 8: 1823-9. PMID 18990070 DOI: 10.1517/14712590802510629  0.6
2008 Kawamura K, Yao K, Shukaliak-Quandt JA, Huh J, Baig M, Quigley L, Ito N, Necker A, McFarland HF, Muraro PA, Martin R, Ito K. Different development of myelin basic protein agonist- and antagonist-specific human TCR transgenic T cells in the thymus and periphery. Journal of Immunology (Baltimore, Md. : 1950). 181: 5462-72. PMID 18832703  0.6
2008 Miller DH, Weinshenker BG, Filippi M, Banwell BL, Cohen JA, Freedman MS, Galetta SL, Hutchinson M, Johnson RT, Kappos L, Kira J, Lublin FD, McFarland HF, Montalban X, Panitch H, et al. Differential diagnosis of suspected multiple sclerosis: a consensus approach. Multiple Sclerosis (Houndmills, Basingstoke, England). 14: 1157-74. PMID 18805839 DOI: 10.1177/1352458508096878  0.6
2008 Petkau J, Reingold SC, Held U, Cutter GR, Fleming TR, Hughes MD, Miller DH, McFarland HF, Wolinsky JS. Magnetic resonance imaging as a surrogate outcome for multiple sclerosis relapses. Multiple Sclerosis (Houndmills, Basingstoke, England). 14: 770-8. PMID 18535021 DOI: 10.1177/1352458507088104  0.6
2008 Polman CH, Reingold SC, Barkhof F, Calabresi PA, Clanet M, Cohen JA, Cutter GR, Freedman MS, Kappos L, Lublin FD, McFarland HF, Metz LM, Miller AE, Montalban X, O'Connor PW, et al. Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment. Neurology. 70: 1134-40. PMID 18362273 DOI: 10.1212/01.wnl.0000306410.84794.4d  0.6
2008 McFarland HF. The B cell--old player, new position on the team. The New England Journal of Medicine. 358: 664-5. PMID 18272890 DOI: 10.1056/NEJMp0708143  0.6
2008 Sonkova P, Evangelou IE, Gallo A, Cantor FK, Ohayon J, McFarland HF, Bagnato F. Semi-automatic segmentation and modeling of the cervical spinal cord for volume quantification in multiple sclerosis patients from magnetic resonance images Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6914. DOI: 10.1117/12.773055  0.6
2007 McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nature Immunology. 8: 913-9. PMID 17712344 DOI: 10.1038/ni1507  0.6
2007 Chiu AW, Ehrmantraut M, Richert ND, Ikonomidou VN, Pellegrini S, McFarland HF, Frank JA, Bagnato F. A case study on the effect of neutralizing antibodies to interferon beta 1b in multiple sclerosis patients followed for 3 years with monthly imaging. Clinical and Experimental Immunology. 150: 61-7. PMID 17666095 DOI: 10.1111/j.1365-2249.2007.03467.x  0.6
2007 Wolinsky JS, Narayana PA, O'Connor P, Coyle PK, Ford C, Johnson K, Miller A, Pardo L, Kadosh S, Ladkani D, Kastrukoff L, Duquette P, Freedman M, Debouverie M, Lubetski C, ... ... McFarland H, et al. Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial Annals of Neurology. 61: 14-24. PMID 17262850 DOI: 10.1002/ana.21079  0.6
2006 Bagnato F, Butman JA, Gupta S, Calabrese M, Pezawas L, Ohayon JM, Tovar-Moll F, Riva M, Cao MM, Talagala SL, McFarland HF. In vivo detection of cortical plaques by MR imaging in patients with multiple sclerosis. Ajnr. American Journal of Neuroradiology. 27: 2161-7. PMID 17110688  0.6
2006 McFarland HF, Jacobson S. Natalizumab and immune cells. Archives of Neurology. 63: 1366-7. PMID 17030649 DOI: 10.1001/archneur.63.10.1366  0.6
2006 Bielekova B, Catalfamo M, Reichert-Scrivner S, Packer A, Cerna M, Waldmann TA, McFarland H, Henkart PA, Martin R. Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 5941-6. PMID 16585503 DOI: 10.1073/pnas.0601335103  0.6
2006 Richert ND, Howard T, Frank JA, Stone R, Ostuni J, Ohayon J, Bash C, McFarland HF. Relationship between inflammatory lesions and cerebral atrophy in multiple sclerosis. Neurology. 66: 551-6. PMID 16505310 DOI: 10.1212/01.wnl.0000197982.78063.06  0.6
2005 Bagnato F, Butman JA, Mora CA, Gupta S, Yamano Y, Tasciyan TA, Solomon JM, Santos WJ, Stone RD, McFarland HF, Jacobson S. Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis. Journal of Neurovirology. 11: 525-34. PMID 16338746 DOI: 10.1080/13550280500385039  0.6
2005 McFarland HF, Reingold SC. The future of multiple sclerosis therapies: redesigning multiple sclerosis clinical trials in a new therapeutic era. Multiple Sclerosis (Houndmills, Basingstoke, England). 11: 669-76. PMID 16320726 DOI: 10.1191/1352458505ms1231oa  0.6
2005 Gupta S, Solomon JM, Tasciyan TA, Cao MM, Stone RD, Ostuni JL, Ohayon JM, Muraro PA, Frank JA, Richert ND, McFarland HF, Bagnato F. Interferon-beta-1b effects on re-enhancing lesions in patients with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 11: 658-68. PMID 16320725 DOI: 10.1191/1352458505ms1229oa  0.6
2005 Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, Lublin FD, Metz LM, McFarland HF, O'Connor PW, Sandberg-Wollheim M, Thompson AJ, Weinshenker BG, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Annals of Neurology. 58: 840-6. PMID 16283615 DOI: 10.1002/ana.20703  0.6
2005 Bielekova B, Kadom N, Fisher E, Jeffries N, Ohayon J, Richert N, Howard T, Bash CN, Frank JA, Stone L, Martin R, Cutter G, McFarland HF. MRI as a marker for disease heterogeneity in multiple sclerosis. Neurology. 65: 1071-6. PMID 16217061 DOI: 10.1212/01.wnl.0000178984.30534.f9  0.6
2005 Bagnato F, Gupta S, Richert ND, Stone RD, Ohayon JM, Frank JA, McFarland HF. Effects of interferon beta-1b on black holes in multiple sclerosis over a 6-year period with monthly evaluations. Archives of Neurology. 62: 1684-8. PMID 16157739 DOI: 10.1001/archneur.62.11.noc40499  0.6
2005 Morgen K, Crawford AL, Stone RD, Martin R, Richert ND, Frank JA, McFarland HF. Contrast-enhanced MRI lesions during treatment with interferonbeta-1b predict increase in T1 black hole volume in patients with relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 11: 146-8. PMID 15794386 DOI: 10.1191/1352458505ms1147oa  0.6
2005 Oh U, Yamano Y, Mora CA, Ohayon J, Bagnato F, Butman JA, Dambrosia J, Leist TP, McFarland H, Jacobson S. Interferon-beta1a therapy in human T-lymphotropic virus type I-associated neurologic disease. Annals of Neurology. 57: 526-34. PMID 15786444 DOI: 10.1002/ana.20429  0.6
2005 Muraro PA, Douek DC, Packer A, Chung K, Guenaga FJ, Cassiani-Ingoni R, Campbell C, Memon S, Nagle JW, Hakim FT, Gress RE, McFarland HF, Burt RK, Martin R. Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients. The Journal of Experimental Medicine. 201: 805-16. PMID 15738052 DOI: 10.1084/jem.20041679  0.6
2005 Ravina B, Eidelberg D, Ahlskog JE, Albin RL, Brooks DJ, Carbon M, Dhawan V, Feigin A, Fahn S, Guttman M, Gwinn-Hardy K, McFarland H, Innis R, Katz RG, Kieburtz K, et al. The role of radiotracer imaging in Parkinson disease. Neurology. 64: 208-15. PMID 15668415 DOI: 10.1212/01.WNL.0000149403.14458.7F  0.6
2004 Morgen K, McFarland HF, Pillemer SR. Central nervous system disease in primary Sjogrens syndrome: the role of magnetic resonance imaging. Seminars in Arthritis and Rheumatism. 34: 623-30. PMID 15609267 DOI: 10.1016/j.semarthrit.2004.07.005  0.6
2004 Kappos L, Weinshenker B, Pozzilli C, Thompson AJ, Dahlke F, Beckmann K, Polman C, McFarland H. Interferon beta-1b in secondary progressive MS: A combined analysis of the two trials Neurology. 63: 1779-1787. PMID 15557490  0.6
2004 Morgen K, Kadom N, Sawaki L, Tessitore A, Ohayon J, McFarland H, Frank J, Martin R, Cohen LG. Training-dependent plasticity in patients with multiple sclerosis. Brain : a Journal of Neurology. 127: 2506-17. PMID 15456705 DOI: 10.1093/brain/awh266  0.6
2004 McFarland HF, Martin R. Re: GAMES issue. Journal of Neuroimmunology. 153: 3. PMID 15334745  0.6
2004 Quandt JA, Baig M, Yao K, Kawamura K, Huh J, Ludwin SK, Bian HJ, Bryant M, Quigley L, Nagy ZA, McFarland HF, Muraro PA, Martin R, Ito K. Unique clinical and pathological features in HLA-DRB1*0401-restricted MBP 111-129-specific humanized TCR transgenic mice. The Journal of Experimental Medicine. 200: 223-34. PMID 15263029 DOI: 10.1084/jem.20030994  0.6
2004 Bielekova B, Richert N, Howard T, Blevins G, Markovic-Plese S, McCartin J, Frank JA, Würfel J, Ohayon J, Waldmann TA, McFarland HF, Martin R. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proceedings of the National Academy of Sciences of the United States of America. 101: 8705-8. PMID 15161974 DOI: 10.1073/pnas.0402653101  0.6
2004 Huh J, Yao K, Quigley L, Ludwin SK, McFarland HF, Muraro PA, Martin R, Ito K. Limited repertoire of HLA-DRB1*0401-restricted MBP111-129-specific T cells in HLA-DRB1*0401 Tg mice and their pathogenic potential. Journal of Neuroimmunology. 151: 94-102. PMID 15145608 DOI: 10.1016/j.jneuroim.2004.02.015  0.6
2004 Anderson SA, Shukaliak-Quandt J, Jordan EK, Arbab AS, Martin R, McFarland H, Frank JA. Magnetic resonance imaging of labeled T-cells in a mouse model of multiple sclerosis. Annals of Neurology. 55: 654-9. PMID 15122705 DOI: 10.1002/ana.20066  0.6
2004 Morgen K, Kadom N, Sawaki L, Tessitore A, Ohayon J, Frank J, McFarland H, Martin R, Cohen LG. Kinematic specificity of cortical reorganization associated with motor training. Neuroimage. 21: 1182-7. PMID 15006685 DOI: 10.1016/j.neuroimage.2003.11.006  0.6
2004 Bielekova B, Sung MH, Kadom N, Simon R, McFarland H, Martin R. Expansion and Functional Relevance of High-Avidity Myelin-Specific CD4 + T Cells in Multiple Sclerosis Journal of Immunology. 172: 3893-3904. PMID 15004197  0.6
2004 Wuerfel J, Bellmann-Strobl J, Brunecker P, Aktas O, McFarland H, Villringer A, Zipp F. Changes in cerebral perfusion precede plaque formation in multiple sclerosis: a longitudinal perfusion MRI study. Brain : a Journal of Neurology. 127: 111-9. PMID 14570816 DOI: 10.1093/brain/awh007  0.6
2004 Frank JA, Richert N, Bash C, Stone L, Calabresi PA, Lewis B, Stone R, Howard T, McFarland HF. Interferon-β-1b slows progression of atrophy in RRMS: Three-year follow-up in NAb- and NAb+ patients Neurology. 62: 719-725. DOI: 10.1212/01.WNL.0000113765.75855.19  0.6
2004 Raine CS, Oksenberg JR, Hauser SL, McFarland HF, Martin R, Weinshenker BG, Kantarci OH, Ebers GC, Sadovnik AD, De Jager PL, Walsh EC, Rioux JD, Hafler DA. Letters to the editors Journal of Neuroimmunology. 153: 1-6. DOI: 10.1016/j.jneuroim.2004.04.017  0.6
2003 Polman C, Barkhof F, Kappos L, Pozzilli C, Sandbrink R, Dahlke F, Jakobs P, Lorenz A, Hern J, Coleman R, Soelberg Srensen P, Hartung HP, Fredrikson S, Selmaj K, Pelletier J, ... ... McFarland HF, et al. Oral interferon beta-1a in relapsing-remitting multiple sclerosis: A double-blind randomized study Multiple Sclerosis. 9: 342-348. PMID 12926838 DOI: 10.1191/1352458503ms923oa  0.6
2003 Bomprezzi R, Ringnér M, Kim S, Bittner ML, Khan J, Chen Y, Elkahloun A, Yu A, Bielekova B, Meltzer PS, Martin R, McFarland HF, Trent JM. Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease. Human Molecular Genetics. 12: 2191-9. PMID 12915464 DOI: 10.1093/hmg/ddg221  0.6
2003 Bagnato F, Jeffries N, Richert ND, Stone RD, Ohayon JM, McFarland HF, Frank JA. Evolution of T1 black holes in patients with multiple sclerosis imaged monthly for 4 years. Brain : a Journal of Neurology. 126: 1782-9. PMID 12821527 DOI: 10.1093/brain/awg182  0.6
2003 Markovic-Plese S, Bielekova B, Kadom N, Leist TP, Martin R, Frank JA, McFarland HF. Longitudinal MRI study: the effects of azathioprine in MS patients refractory to interferon beta-1b. Neurology. 60: 1849-51. PMID 12796549  0.6
2003 Stürzebecher S, Wandinger KP, Rosenwald A, Sathyamoorthy M, Tzou A, Mattar P, Frank JA, Staudt L, Martin R, McFarland HF. Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis. Brain : a Journal of Neurology. 126: 1419-29. PMID 12764062 DOI: 10.1093/brain/awg147  0.6
2003 Muraro PA, Wandinger KP, Bielekova B, Gran B, Marques A, Utz U, McFarland HF, Jacobson S, Martin R. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain : a Journal of Neurology. 126: 20-31. PMID 12477694 DOI: 10.1093/brain/awg021  0.6
2002 Calabresi PA, Austin H, Racke MK, Goodman A, Choyke P, Maloni H, McFarland HF. Impaired renal function in progressive multiple sclerosis. Neurology. 59: 1799-801. PMID 12473777  0.6
2002 Leigh R, Ostuni J, Pham D, Goldszal A, Lewis BK, Howard T, Richert N, McFarland H, Frank JA. Estimating cerebral atrophy in multiple sclerosis patients from various MR pulse sequences. Multiple Sclerosis (Houndmills, Basingstoke, England). 8: 420-9. PMID 12356210 DOI: 10.1191/1352458502ms801oa  0.6
2002 Muraro PA, Kalbus M, Afshar G, McFarland HF, Martin R. T cell response to 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) in multiple sclerosis patients. Journal of Neuroimmunology. 130: 233-42. PMID 12225906 DOI: 10.1016/S0165-5728(02)00229-1  0.6
2002 Rao AB, Richert N, Howard T, Lewis BK, Bash CN, McFarland HF, Frank JA. Methylprednisolone effect on brain volume and enhancing lesions in MS before and during IFNbeta-1b. Neurology. 59: 688-94. PMID 12221158  0.6
2002 Berti R, Brennan MB, Soldan SS, Ohayon JM, Casareto L, McFarland HF, Jacobson S. Increased detection of serum HHV-6 DNA sequences during multiple sclerosis (MS) exacerbations and correlation with parameters of MS disease progression. Journal of Neurovirology. 8: 250-6. PMID 12053279 DOI: 10.1080/13550280290049615-1  0.6
2002 Filippi M, Dousset V, McFarland HF, Miller DH, Grossman RI. Role of magnetic resonance imaging in the diagnosis and monitoring of multiple sclerosis: consensus report of the White Matter Study Group. Journal of Magnetic Resonance Imaging : Jmri. 15: 499-504. PMID 11997889 DOI: 10.1002/jmri.10097  0.6
2002 Tedeschi G, Bonavita S, McFarland HF, Richert N, Duyn JH, Frank JA. Proton MR spectroscopic imaging in multiple sclerosis. Neuroradiology. 44: 37-42. PMID 11942498 DOI: 10.1007/s002340100584  0.6
2002 McFarland HF. The emerging role of MRI in multiple sclerosis and the new diagnostic criteria. Multiple Sclerosis (Houndmills, Basingstoke, England). 8: 71-2. PMID 11936491  0.6
2002 McFarland HF, Barkhof F, Antel J, Miller DH. The role of MRI as a surrogate outcome measure in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 8: 40-51. PMID 11936488 DOI: 10.1191/1352458502ms767xx  0.6
2002 Frank JA, Richert N, Lewis B, Bash C, Howard T, Civil R, Stone R, Eaton J, McFarland H, Leist T. A pilot study of recombinant insulin-like growth factor-I in seven multiple sclerosis patients Multiple Sclerosis. 8: 24-29. PMID 11936485 DOI: 10.1191/1352458502ms768oa  0.6
2001 Markovic-Plese S, McFarland HF. Immunopathogenesis of the multiple sclerosis lesion. Current Neurology and Neuroscience Reports. 1: 257-62. PMID 11898527  0.6
2001 Morgen K, Martin R, Stone RD, Grafman J, Kadom N, McFarland HF, Marques A. FLAIR and magnetization transfer imaging of patients with post-treatment Lyme disease syndrome. Neurology. 57: 1980-5. PMID 11739813  0.6
2001 Whitney LW, Ludwin SK, McFarland HF, Biddison WE. Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions. Journal of Neuroimmunology. 121: 40-8. PMID 11730938 DOI: 10.1016/S0165-5728(01)00438-6  0.6
2001 Soldan SS, Fogdell-Hahn A, Brennan MB, Mittleman BB, Ballerini C, Massacesi L, Seya T, McFarland HF, Jacobson S. Elevated serum and cerebrospinal fluid levels of soluble human herpesvirus type 6 cellular receptor, membrane cofactor protein, in patients with multiple sclerosis. Annals of Neurology. 50: 486-93. PMID 11603380 DOI: 10.1002/ana.1135  0.6
2001 Markovic-Plese S, Cortese I, Wandinger KP, McFarland HF, Martin R. CD4+CD28- costimulation-independent T cells in multiple sclerosis. The Journal of Clinical Investigation. 108: 1185-94. PMID 11602626 DOI: 10.1172/JCI12516  0.6
2001 Wandinger KP, Stürzebecher CS, Bielekova B, Detore G, Rosenwald A, Staudt LM, McFarland HF, Martin R. Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes. Annals of Neurology. 50: 349-57. PMID 11558791 DOI: 10.1002/ana.1096  0.6
2001 Martin R, Stürzebecher CS, McFarland HF. Immunotherapy of multiple sclerosis: where are we? Where should we go? Nature Immunology. 2: 785-8. PMID 11526386 DOI: 10.1038/ni0901-785  0.6
2001 Morgen K, Jeffries NO, Stone R, Martin R, Richert ND, Frank JA, McFarland HF. Ring-enchancement in multiple sclerosis: marker of disease severity. Multiple Sclerosis (Houndmills, Basingstoke, England). 7: 167-71. PMID 11475440 DOI: 10.1191/135245801678438393  0.6
2001 McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, McFarland HF, Paty DW, Polman CH, Reingold SC, Sandberg-Wollheim M, Sibley W, Thompson A, van den Noort S, Weinshenker BY, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of Neurology. 50: 121-7. PMID 11456302 DOI: 10.1002/ana.1032  0.6
2001 Martin R, Gran B, Zhao Y, Markovic-Plese S, Bielekova B, Marques A, Sung MH, Hemmer B, Simon R, McFarland HF, Pinilla C. Molecular mimicry and antigen-specific T cell responses in multiple sclerosis and chronic CNS Lyme disease. Journal of Autoimmunity. 16: 187-92. PMID 11334482 DOI: 10.1006/jaut.2000.0501  0.6
2001 Richert ND, Ostuni JL, Bash CN, Leist TP, McFarland HF, Frank JA. Interferon beta-1b and intravenous methylprednisolone promote lesion recovery in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 7: 49-58. PMID 11321194 DOI: 10.1191/135245801669116174  0.6
2001 Leist TP, Gobbini MI, Frank JA, McFarland HF. Enhancing magnetic resonance imaging lesions and cerebral atrophy in patients with relapsing multiple sclerosis. Archives of Neurology. 58: 57-60. PMID 11176937  0.6
2000 Frank JA, McFarland HF. How to participate in a multiple sclerosis clinical trial. Neuroimaging Clinics of North America. 10: 817-30 ,x. PMID 11359727  0.6
2000 Martin R, Bielekova B, Gran B, McFarland HF. Lessons from studies of antigen-specific T cell responses in Multiple Sclerosis. Journal of Neural Transmission. Supplementum. 361-73. PMID 11205154  0.6
2000 Muraro PA, Leist T, Bielekova B, McFarland HF. VLA-4/CD49d downregulated on primed T lymphocytes during interferon-beta therapy in multiple sclerosis. Journal of Neuroimmunology. 111: 186-94. PMID 11063837 DOI: 10.1016/S0165-5728(00)00362-3  0.6
2000 Akhyani N, Berti R, Brennan MB, Soldan SS, Eaton JM, McFarland HF, Jacobson S. Tissue distribution and variant characterization of human herpesvirus (HHV)-6: increased prevalence of HHV-6A in patients with multiple sclerosis. The Journal of Infectious Diseases. 182: 1321-5. PMID 11023456 DOI: 10.1086/315893  0.6
2000 Bielekova B, Goodwin B, Richert N, Cortese I, Kondo T, Afshar G, Gran B, Eaton J, Antel J, Frank JA, McFarland HF, Martin R. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nature Medicine. 6: 1167-75. PMID 11017150 DOI: 10.1038/80516  0.6
2000 Berti R, Soldan SS, Akhyani N, McFarland HF, Jacobson S. Extended observations on the association of HHV-6 and multiple sclerosis. Journal of Neurovirology. 6: S85-7. PMID 10871792  0.6
2000 Muraro PA, Pette M, Bielekova B, McFarland HF, Martin R. Human autoreactive CD4+ T cells from naive CD45RA+ and memory CD45RO+ subsets differ with respect to epitope specificity and functional antigen avidity. Journal of Immunology (Baltimore, Md. : 1950). 164: 5474-81. PMID 10799915  0.6
2000 Burt RK, Brenner M, Burns W, Courier E, Firestein G, Hahn B, Heslop H, Link C, McFarland H, Roland M, Territo M, Tsokos G, Traynor A. Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease. Journal of Clinical Immunology. 20: 1-9. PMID 10798601 DOI: 10.1023/A:1006673408343  0.6
2000 Richert ND, Zierak MC, Bash CN, Lewis BK, McFarland HF, Frank JA. MRI and clinical activity in MS patients after terminating treatment with interferon beta-1b. Multiple Sclerosis (Houndmills, Basingstoke, England). 6: 86-90. PMID 10773853  0.6
2000 Soldan SS, Leist TP, Juhng KN, McFarland HF, Jacobson S. Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients. Annals of Neurology. 47: 306-13. PMID 10716249 DOI: 10.1002/1531-8249(200003)47:3<306::AID-ANA5>3.0.CO;2-A  0.6
2000 Singer BA, Tresser NJ, Frank JA, McFarland HF, Biddison WE. Induction of experimental allergic encephalomyelitis in the NIH minipig. Journal of Neuroimmunology. 105: 7-19. PMID 10713359 DOI: 10.1016/S0165-5728(99)00275-1  0.6
2000 Hemmer B, Kondo T, Gran B, Pinilla C, Cortese I, Pascal J, Tzou A, McFarland HF, Houghten R, Martin R. Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival. International Immunology. 12: 375-83. PMID 10700472  0.6
2000 Peters TR, Bodine DM, McDonagh KT, Lovett-Racke A, McFarland HF, McFarlin DE, Nienhuis AW, Racke MK. Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 103: 51-62. PMID 10674989 DOI: 10.1016/S0165-5728(99)00181-2  0.6
2000 Mazzanti B, Hemmer B, Traggiai E, Ballerini C, McFarland HF, Massacesi L, Martin R, Vergelli M. Decrypting the spectrum of antigen-specific T-cell responses: the avidity repertoire of MBP-specific T-cells. Journal of Neuroscience Research. 59: 86-93. PMID 10658188 DOI: 10.1002/(SICI)1097-4547(20000101)59:1<86::AID-JNR10>3.0.CO;2-U  0.6
2000 Hemmer B, Pinilla C, Gran B, Vergelli M, Ling N, Conlon P, McFarland HF, Houghten R, Martin R. Contribution of individual amino acids within MHC molecule or antigenic peptide to TCR ligand potency. Journal of Immunology (Baltimore, Md. : 1950). 164: 861-71. PMID 10623833  0.6
1999 Bielekova B, Muraro PA, Golestaneh L, Pascal J, McFarland HF, Martin R. Preferential expansion of autoreactive T lymphocytes from the memory T-cell pool by IL-7. Journal of Neuroimmunology. 100: 115-23. PMID 10695722 DOI: 10.1016/S0165-5728(99)00200-3  0.6
1999 McFarland HF. Correlation between MR and clinical findings of disease activity in multiple sclerosis. Ajnr. American Journal of Neuroradiology. 20: 1777-8. PMID 10588096  0.6
1999 Hemmer B, Gran B, Zhao Y, Marques A, Pascal J, Tzou A, Kondo T, Cortese I, Bielekova B, Straus SE, McFarland HF, Houghten R, Simon R, Pinilla C, Martin R. Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nature Medicine. 5: 1375-82. PMID 10581079 DOI: 10.1038/70946  0.6
1999 Smith ME, Eller NL, McFarland HF, Racke MK, Raine CS. Age dependence of clinical and pathological manifestations of autoimmune demyelination. Implications for multiple sclerosis. The American Journal of Pathology. 155: 1147-61. PMID 10514398 DOI: 10.1016/S0002-9440(10)65218-2  0.6
1999 Gobbini MI, Smith ME, Richert ND, Frank JA, McFarland HF. Effect of open label pulse cyclophosphamide therapy on MRI measures of disease activity in five patients with refractory relapsing-remitting multiple sclerosis. Journal of Neuroimmunology. 99: 142-9. PMID 10496187 DOI: 10.1016/S0165-5728(99)00039-9  0.6
1999 Whitney LW, Becker KG, Tresser NJ, Caballero-Ramos CI, Munson PJ, Prabhu VV, Trent JM, McFarland HF, Biddison WE. Analysis of gene expression in mutiple sclerosis lesions using cDNA microarrays. Annals of Neurology. 46: 425-8. PMID 10482277 DOI: 10.1002/1531-8249(199909)46:3<425::AID-ANA22>3.0.CO;2-O  0.6
1999 Fazekas F, Barkhof F, Filippi M, Grossman RI, Li DK, McDonald WI, McFarland HF, Paty DW, Simon JH, Wolinsky JS, Miller DH. The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis. Neurology. 53: 448-56. PMID 10449103  0.6
1999 Jordan EK, McFarland HI, Lewis BK, Tresser N, Gates MA, Johnson M, Lenardo M, Matis LA, McFarland HF, Frank JA. Serial MR imaging of experimental autoimmune encephalomyelitis induced by human white matter or by chimeric myelin-basic and proteolipid protein in the common marmoset. Ajnr. American Journal of Neuroradiology. 20: 965-76. PMID 10445431  0.6
1999 McFarland HF. The path to damage in multiple sclerosis. Annals of Neurology. 46: 141-2. PMID 10443877 DOI: 10.1002/1531-8249(199908)46:2<141::AID-ANA1>3.0.CO;2-Z  0.6
1999 Pette M, Muraro PA, Pette DF, Dinter H, McFarland HF, Martin R. Differential effects of phosphodiesterase type 4-specific inhibition on human autoreactive myelin-specific T cell clones. Journal of Neuroimmunology. 98: 147-56. PMID 10430048 DOI: 10.1016/S0165-5728(99)00088-0  0.6
1999 Gran B, Hemmer B, Vergelli M, McFarland HF, Martin R. Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity. Annals of Neurology. 45: 559-67. PMID 10319877 DOI: 10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q  0.6
1998 Lehky TJ, Levin MC, Kubota R, Bamford RN, Flerlage AN, Soldan SS, Leist TP, Xavier A, White JD, Brown M, Fleisher TA, Top LE, Light S, McFarland HF, Waldmann TA, et al. Reduction in HTLV-I proviral load and spontaneous lymphoproliferation in HTLV-I-associated myelopathy/tropical spastic paraparesis patients treated with humanized anti-Tac. Annals of Neurology. 44: 942-7. PMID 9851439 DOI: 10.1002/ana.410440613  0.6
1998 Richert ND, Ostuni JL, Bash CN, Duyn JH, McFarland HF, Frank JA. Serial whole-brain magnetization transfer imaging in patients with relapsing-remitting multiple sclerosis at baseline and during treatment with interferon beta-1b. Ajnr. American Journal of Neuroradiology. 19: 1705-13. PMID 9802494  0.6
1998 Calabresi PA, Tranquill LR, McFarland HF, Cowan EP. Cytokine gene expression in cells derived from CSF of multiple sclerosis patients. Journal of Neuroimmunology. 89: 198-205. PMID 9726843 DOI: 10.1016/S0165-5728(98)00139-8  0.6
1998 Becker KG, Simon RM, Bailey-Wilson JE, Freidlin B, Biddison WE, McFarland HF, Trent JM. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 95: 9979-84. PMID 9707586 DOI: 10.1073/pnas.95.17.9979  0.6
1998 Calabresi PA, Fields NS, Maloni HW, Hanham A, Carlino J, Moore J, Levin MC, Dhib-Jalbut S, Tranquill LR, Austin H, McFarland HF, Racke MK. Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS. Neurology. 51: 289-92. PMID 9674825  0.6
1998 Reinhold D, Hemmer B, Gran B, Born I, Faust J, Neubert K, McFarland HF, Martin R, Ansorge S. Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones. Journal of Neuroimmunology. 87: 203-9. PMID 9670864 DOI: 10.1016/S0165-5728(98)00100-3  0.6
1998 McFarland HF. The lesion in multiple sclerosis: clinical, pathological, and magnetic resonance imaging considerations. Journal of Neurology, Neurosurgery, and Psychiatry. 64: S26-30. PMID 9647281  0.6
1998 Xu S, Jordan EK, Brocke S, Bulte JW, Quigley L, Tresser N, Ostuni JL, Yang Y, McFarland HF, Frank JA. Study of relapsing remitting experimental allergic encephalomyelitis SJL mouse model using MION-46L enhanced in vivo MRI: early histopathological correlation. Journal of Neuroscience Research. 52: 549-58. PMID 9632311 DOI: 10.1002/(SICI)1097-4547(19980601)52:5<549::AID-JNR7>3.0.CO;2-C  0.6
1998 Calabresi PA, Fields NS, Farnon EC, Frank JA, Bash CN, Kawanashi T, Maloni H, Jacobson S, McFarland HF. ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions. Journal of Neuroimmunology. 85: 212-9. PMID 9630170 DOI: 10.1016/S0165-5728(98)00008-3  0.6
1998 Trotter JL, Pelfrey CM, Trotter AL, Selvidge JA, Gushleff KC, Mohanakumar T, McFarland HF. T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects. Journal of Neuroimmunology. 84: 172-8. PMID 9628460 DOI: 10.1016/S0165-5728(97)00260-9  0.6
1998 Afshar G, Muraro PA, McFarland HF, Martin R. Lack of over-expression of T cell receptor Vβ5.2 in myelin basic protein-specific T cell lines derived from HLA-DR2 positive multiple sclerosis patients and controls Journal of Neuroimmunology. 84: 7-13. PMID 9600703 DOI: 10.1016/S0165-5728(97)00215-4  0.6
1998 Li W, Quigley L, Yao DL, Hudson LD, Brenner M, Zhang BJ, Brocke S, McFarland HF, Webster HD. Chronic relapsing experimental autoimmune encephalomyelitis: effects of insulin-like growth factor-I treatment on clinical deficits, lesion severity, glial responses, and blood brain barrier defects. Journal of Neuropathology and Experimental Neurology. 57: 426-38. PMID 9596413  0.6
1998 Xu S, Jordan EK, Li W, Yang Y, Chesnick SA, Webster HD, Brocke S, Quigley L, McFarland HF, Frank JA. In vivo three-dimensional MR microscopy of mice with chronic relapsing experimental autoimmune encephalomyelitis after treatment with insulin-like growth factor-I. Ajnr. American Journal of Neuroradiology. 19: 653-8. PMID 9576650  0.6
1998 Hemmer B, Vergelli M, Gran B, Ling N, Conlon P, Pinilla C, Houghten R, McFarland HF, Martin R. Cutting edge: Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology Journal of Immunology. 160: 3631-3636. PMID 9558061  0.6
1998 Miller DH, Grossman RI, Reingold SC, McFarland HF. The role of magnetic resonance techniques in understanding and managing multiple sclerosis Brain. 121: 3-24. PMID 9549485 DOI: 10.1093/brain/121.1.3  0.6
1998 Filippi M, Horsfield MA, Adèr HJ, Barkhof F, Bruzzi P, Evans A, Frank JA, Grossman RI, McFarland HF, Molyneux P, Paty DW, Simon J, Tofts PS, Wolinsky JS, Miller DH. Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities in monitoring the treatment of multiple sclerosis Annals of Neurology. 43: 499-506. PMID 9546332 DOI: 10.1002/ana.410430414  0.6
1998 Mazzanti B, Vergelli M, Riccio P, Martin R, McFarland HF, Liuzzi GM, Amaducci L, Massacesi L. T-cell response to myelin basic protein and lipid-bound myelin basic protein in patients with multiple sclerosis and healthy donors. Journal of Neuroimmunology. 82: 96-100. PMID 9526851 DOI: 10.1016/S0165-5728(97)00194-X  0.6
1998 Zipp F, Weller M, Calabresi PA, Frank JA, Bash CN, Dichgans J, McFarland HF, Martin R. Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis. Annals of Neurology. 43: 116-20. PMID 9450777 DOI: 10.1002/ana.410430120  0.6
1998 Martin R, Vergelli M, Gran B, Ling N, Conlon P, McFarland HF, Hemmer B. Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology Faseb Journal. 12: A625.  0.6
1998 Gran B, Martin R, Pascal J, Tranquill L, Pinilla C, Tzou A, McFarland HF, Houghten R, Hemmer B. Activation of human class-II restricted T cell clones by short peptides Faseb Journal. 12: A625.  0.6
1998 Hemmer B, Pinilla C, Gran B, Conlon P, Ling N, McFarland HF, Houghten R, Martin R. Precise prediction of class II T-cell epitopes using a combinatorial peptide library approach Faseb Journal. 12: A625.  0.6
1998 Filippi M, Comi G, Mcfarland HF, Miller DH. Magnetic Resonance Techniques in Multiple Sclerosis. First Advanced Course, Milan, 15-17 May 1997: Introduction Journal of Neurology Neurosurgery and Psychiatry. 64: S1.  0.6
1997 Dhib-Jalbut S, McFarland HF. Treatment of multiple sclerosis with interferon beta 1b. BaillièRe's Clinical Neurology. 6: 467-80. PMID 10101584  0.6
1997 Soldan SS, Berti R, Salem N, Secchiero P, Flamand L, Calabresi PA, Brennan MB, Maloni HW, McFarland HF, Lin HC, Patnaik M, Jacobson S. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nature Medicine. 3: 1394-7. PMID 9396611 DOI: 10.1038/nm1297-1394  0.6
1997 Sommer N, Martin R, McFarland HF, Quigley L, Cannella B, Raine CS, Scott DE, Löschmann PA, Racke MK. Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease. Journal of Neuroimmunology. 79: 54-61. PMID 9357447 DOI: 10.1016/S0165-5728(97)00111-2  0.6
1997 Hemmer B, Vergelli M, Tranquill L, Conlon P, Ling N, McFarland HF, Martin R. Human T-cell response to myelin basic protein peptide (83-99): Extensive heterogeneity in antigen recognition, function, and phenotype Neurology. 49: 1116-1126. PMID 9339699  0.6
1997 Calabresi PA, Pelfrey CM, Tranquill LR, Maloni H, McFarland HF. VLA-4 expression on peripheral blood lymphocytes is downregulated after treatment of multiple sclerosis with interferon beta. Neurology. 49: 1111-6. PMID 9339698  0.6
1997 Lovett-Racke AE, Martin R, McFarland HF, Racke MK, Utz U. Longitudinal study of myelin basic protein-specific T-cell receptors during the course of multiple sclerosis Journal of Neuroimmunology. 78: 162-171. PMID 9307241 DOI: 10.1016/S0165-5728(97)00097-0  0.6
1997 Stone LA, Frank JA, Albert PS, Bash CN, Calabresi PA, Maloni H, McFarland HF. Characterization of MRI response to treatment with interferon beta-1b: contrast-enhancing MRI lesion frequency as a primary outcome measure. Neurology. 49: 862-9. PMID 9305355  0.6
1997 Pette M, Pette DF, Muraro PA, Farnon E, Martin R, McFarland HF. Interferon-β interferes with the proliferation but not with the cytokine secretion of myelin basic protein-specific, T-helper type 1 lymphocytes Neurology. 49: 385-392. PMID 9270566  0.6
1997 Vergelli M, Kalbus M, Rojo SC, Hemmer B, Kalbacher H, Tranquill L, Beck H, McFarland HF, De Mars R, Long EO, Martin R. T cell response to myelin basic protein in the context of the multiple sclerosis-associated HLA-DR15 haplotype: Peptide binding, immunodominance and effector functions of T cells Journal of Neuroimmunology. 77: 195-203. PMID 9258250 DOI: 10.1016/S0165-5728(97)00075-1  0.6
1997 Muraro PA, Vergelli M, Kalbus M, Banks DE, Nagle JW, Tranquill LR, Nepom GT, Biddison WE, McFarland HF, Martin R. Immunodominance of a low-affinity major histocompatibility complex- binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire Journal of Clinical Investigation. 100: 339-349. PMID 9218510  0.6
1997 Capello E, Voskuhl RR, McFarland HF, Raine CS. Multiple sclerosis: re-expression of a developmental gene in chronic lesions correlates with remyelination. Annals of Neurology. 41: 797-805. PMID 9189041 DOI: 10.1002/ana.410410616  0.6
1997 Pette M, Pette DF, Muraro PA, Martin R, McFarland HF. In vitro modulation of human, autoreactive MBP-specific CD4 + T-cell clones by cyclosporin A Journal of Neuroimmunology. 76: 91-99. PMID 9184637 DOI: 10.1016/S0165-5728(97)00035-0  0.6
1997 Calabresi PA, Tranquill LR, Dambrosia JM, Stone LA, Maloni H, Bash CN, Frank JA, McFarland HF. Increases in soluble VCAM-1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon beta-1b. Annals of Neurology. 41: 669-74. PMID 9153530 DOI: 10.1002/ana.410410517  0.6
1997 Calabresi PA, Stone LA, Bash CN, Frank JA, McFarland HF. Interferon beta results in immediate reduction of contrast-enhanced MRI lesions in multiple sclerosis patients followed by weekly MRI. Neurology. 48: 1446-8. PMID 9153489  0.6
1997 Trotter JL, Damico CA, Cross AH, Pelfrey CM, Karr RW, Fu XT, McFarland HF. HPRT mutant T-cell lines from multiple sclerosis patients recognize myelin proteolipid protein peptides. Journal of Neuroimmunology. 75: 95-103. PMID 9143242 DOI: 10.1016/S0165-5728(97)00007-6  0.6
1997 Rösener M, Muraro PA, Riethmüller A, Kalbus M, Sappler G, Thompson RJ, Lichtenfels R, Sommer N, McFarland HF, Martin R. 2',3'-cyclic nucleotide 3'-phosphodiesterase: a novel candidate autoantigen in demyelinating diseases. Journal of Neuroimmunology. 75: 28-34. PMID 9143234 DOI: 10.1016/S0165-5728(96)00230-5  0.6
1997 Levin MC, Lehky TJ, Flerlage AN, Katz D, Kingma DW, Jaffe ES, Heiss JD, Patronas N, Mcfarland HF, Jacobson S. Immunologic analysis of a spinal cord-biopsy specimen from a patient with human T-cell lymphotropic virus type I-associated neurologic disease New England Journal of Medicine. 336: 839-845. PMID 9062093 DOI: 10.1056/NEJM199703203361205  0.6
1997 Vergelli M, Hemmer B, Muraro PA, Tranquill L, Biddison WE, Sarin A, McFarland HF, Martin R. Human Autoreactive CD4+ T Cell Clones Use Perforin- or Fas/Fas Ligand-Mediated Pathways for Target Cell Lysis Journal of Immunology. 158: 2756-2761. PMID 9058810  0.6
1997 Honma K, Parker KC, Becker KG, McFarland HF, Coligan JE, Biddison WE. Identification of an epitope derived from human proteolipid protei nthat can induce autoreactive CD8+ cytotoxic T lymphocytes restricted by HLA-A3: Evidence for cross-reactivity with an environmental microorganism Journal of Neuroimmunology. 73: 7-14. PMID 9058754 DOI: 10.1016/S0165-5728(96)00161-0  0.6
1997 Eo C, Voskuhl R, McFarland HF, Gl M, Cs R. Differential expression of a novel candidate auto-antigen, X2 MBP, in multiple sclerosis (MS) lesions Italian Journal of Neurological Sciences. 18: 31.  0.6
1997 Grekova MC, Salerno K, McFarland HF, Richert JR. Deficient expression of the transcription factor Sp3 in multiple sclerosis immune cells Multiple Sclerosis. 3: 404.  0.6
1996 Pelfrey CM, Tranquill LR, Vogt AB, McFarland HF. T cell response to two immunodominant proteolipid protein (PLP) peptides in multiple sclerosis patients and healthy controls Multiple Sclerosis. 1: 270-278. PMID 9345429  0.6
1996 McFarland HF, Stone LA, Calabresi PA, Maloni H, Bash CN, Frank JA. MRI studies of multiple sclerosis: implications for the natural history of the disease and for monitoring effectiveness of experimental therapies. Multiple Sclerosis (Houndmills, Basingstoke, England). 2: 198-205. PMID 9345374  0.6
1996 McFarland HF. Complexities in the treatment of autoimmune disease Science. 274: 2037-2038. PMID 8984662 DOI: 10.1126/science.274.5295.2037  0.6
1996 Liedtke W, Limmroth V, Stone LA, Frank JA, McFarland HF. Validity of brain MRI as the primary outcome criterion in multiple sclerosis phase II clinical trials [1] Annals of Neurology. 39: 276-277. PMID 8967762  0.6
1996 Stüber A, Martin R, Stone LA, Maloni H, McFarland HF. Expression pattern of activation and adhesion molecules on peripheral blood CD4+ T-lymphocytes in relapsing-remitting multiple sclerosis patients: A serial analysis Journal of Neuroimmunology. 66: 147-151. PMID 8964909 DOI: 10.1016/0165-5728(96)00026-4  0.6
1996 Lehky TJ, Flerlage N, Katz D, Houff S, Hall WH, Ishii K, Monken C, Dhib-Jalbut S, McFarland HF, Jacobson S. Human T-cell lymphotropic virus type II-associated myelopathy: Clinical and immunologic profiles Annals of Neurology. 40: 714-723. PMID 8957012  0.6
1996 Vergelli M, Hemmer B, Utz U, Vogt A, Kalbus M, Tranquill L, Conlon P, Ling N, Steinman L, McFarland HF, Martin R. Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99) European Journal of Immunology. 26: 2624-2634. PMID 8921948 DOI: 10.1002/eji.1830261113  0.6
1996 Voskuhl RR, Farris RW, Nagasato K, McFarland HF, Dalcq MD. Epitope spreading occurs in active but not passive EAE induced by myelin basic protein Journal of Neuroimmunology. 70: 103-111. PMID 8898718 DOI: 10.1016/S0165-5728(96)00054-9  0.6
1996 Hemmer B, Vergelli M, Calabresi P, Huang T, McFarland HF, Martin R. Cytokine phenotype of human autoreactive T cell clones specific for the immunodominant myelin basic protein peptide (83-99) Journal of Neuroscience Research. 45: 852-862. PMID 8892097  0.6
1996 Tranquill LR, Skinner E, Campagnoni C, Vergelli M, Hemmer B, Muraro P, Martin R, McFarland HF, Campagnoni AT, Voskuhl RR. Human T lymphocytes specific for the immunodominant 83-99 epitope of myelin basic protein: recognition of golli MBP HOG 7. Journal of Neuroscience Research. 45: 820-8. PMID 8892094 DOI: 10.1002/(SICI)1097-4547(19960915)45:6<820::AID-JNR19>3.0.CO;2-Z  0.6
1996 Grekova MC, Robinson ED, Faerber MA, Katz P, McFarland HF, Richert JR. Deficient expression in multiple sclerosis of the inhibitory transcription factor Sp3 in mononuclear blood cells Annals of Neurology. 40: 108-112. PMID 8687178 DOI: 10.1002/ana.410400117  0.6
1996 Voskuhl RR, Goldstein AM, Simonis T, Davey RJ, McFarland HF. DR2/DQw1 inheritance and haplotype sharing in affected siblings from multiple sclerosis families Annals of Neurology. 39: 804-807. PMID 8651654 DOI: 10.1002/ana.410390618  0.6
1996 Voskuhl RR, Pitchekian-Halabi H, MacKenzie-Graham A, McFarland HF, Raine CS. Gender differences in autoimmune demyelination in the mouse: implications for multiple sclerosis. Annals of Neurology. 39: 724-33. PMID 8651644 DOI: 10.1002/ana.410390608  0.6
1996 Racke MK, Critchfield JM, Quigley L, Cannella B, Raine CS, McFarland HF, Lenardo MJ. Intravenous antigen administration as a therapy for autoimmune demyelinating disease. Annals of Neurology. 39: 46-56. PMID 8572666 DOI: 10.1002/ana.410390108  0.6
1996 Brocke S, Quigley L, McFarland HF, Steinman L. Isolation and characterization of autoreactive T cells in experimental autoimmune encephalomyelitis of the mouse Methods: a Companion to Methods in Enzymology. 9: 458-462. DOI: 10.1006/meth.1996.0053  0.6
1996 Pitchekian-Haiabi H, Kirn S, Mackenzie-Graham A, McFarland HF, Raine OS, Voskuhl RR. Gender differences in autoimmune demyelination in the mouse; implications for multiple sclerosis Faseb Journal. 10: A1353.  0.6
1995 Whitaker JN, McFarland HF, Rudge P, Reingold SC. Outcomes assessment in multiple sclerosis clinical trials: a critical analysis Multiple Sclerosis (Houndmills, Basingstoke, England). 1: 37-47. PMID 9345468  0.6
1995 Stone LA, Smith ME, Albert PS, Bash CN, Maloni H, Frank JA, McFarland HF. Blood-brain barrier disruption on contrast-enhanced mri in patients with mild relapsing-remitting multiple sclerosis: Relationship to course, gender, and age Neurology. 45: 1122-1126. PMID 7783875  0.6
1995 Stone LA, Frank JA, Albert PS, Bash C, Smith ME, Maloni H, McFarland HF. The effect of interferon-β on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis Annals of Neurology. 37: 611-619. PMID 7755356  0.6
1995 McFarland HF. The multiple sclerosis lesion Annals of Neurology. 37: 419-421. PMID 7717677 DOI: 10.1002/ana.410370402  0.6
1995 Martin R, McFarland HF. Multiple sclerosis: Are HLA class I molecules involved in disease pathogenesis? Annals of Neurology. 38: 137-139. PMID 7654058 DOI: 10.1002/ana.410380202  0.6
1995 Martin R, Mcfarland HF, Boggs JM. Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis Critical Reviews in Clinical Laboratory Sciences. 32: 121-182. PMID 7598789 DOI: 10.3109/10408369509084683  0.6
1995 Richert JR, Robinson ED, Johnson AH, Cohn ML, McFarland HF, Hurley CK. Myelin basic protein-reactive human T-cell clones: stimulation by diverse microbial antigens. Annals of the New York Academy of Sciences. 756: 319-20. PMID 7544081 DOI: 10.1111/j.1749-6632.1995.tb44532.x  0.6
1995 Richert JR, Robinson ED, Camphausen K, Hastings E, Martin R, Voskuhl R, McFarland HF. T-cell receptor alpha and beta CDR3 expression by myelin basic protein-specific human T-cell clones. Annals of the New York Academy of Sciences. 756: 317-8. PMID 7544080 DOI: 10.1111/j.1749-6632.1995.tb44531.x  0.6
1995 Utz U, Martin R, Brooks JA, Biddison WE, McFarland HF. T-cell receptor use in multiple sclerosis. Annals of the New York Academy of Sciences. 756: 259-64. PMID 7544076 DOI: 10.1111/j.1749-6632.1995.tb44523.x  0.6
1995 Pelfrey CM, Tranquill LR, Boehme SA, McFarland HF, Lenardo MJ. Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals Journal of Immunology. 154: 6191-6202. PMID 7538545  0.6
1995 Richert JR, Robinson ED, Camphausen K, Martin R, Voskuhl RR, Faerber MA, McFarland HF, Hurley CK. Diversity of T-cell receptor V(α), V(β), and CDR3 expression by myelin basic protein-specific human T-cell clones Neurology. 45: 1919-1922. PMID 7477993  0.6
1995 Stone LA, Albert PS, Smith ME, DeCarli C, Armstrong MR, McFarlin DE, Frank JA, McFarland HF. Changes in the amount of diseased white matter over time in patients with relapsing-remitting multiple sclerosis. Neurology. 45: 1808-14. PMID 7477973  0.6
1994 McFarland HF. Significance of autoreactive T cells in diseases such as multiple sclerosis using an innovative primate model Journal of Clinical Investigation. 94: 921-922. PMID 8083376  0.6
1994 Allegretta M, Albertini RJ, Howell MD, Smith LR, Martin R, McFarland HF, Sriram S, Brostoff S, Steinman L. Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis Journal of Clinical Investigation. 94: 105-109. PMID 8040252  0.6
1994 Albert PS, McFarland HF, Smith ME, Frank JA. Time series for modelling counts from a relapsing-remitting disease: Application to modelling disease activity in multiple sclerosis Statistics in Medicine. 13: 453-466. PMID 8023028  0.6
1994 Utz U, McFarland HF. The role of T cells in multiple sclerosis implications for therapies targeting the T cell receptor Journal of Neuropathology and Experimental Neurology. 53: 351-358. PMID 8021708  0.6
1994 Frank JA, Stone LA, Smith ME, Albert PS, Maloni H, McFarland HF. Serial contrast-enhanced magnetic resonance imaging in patients with early relapsing-remitting multiple sclerosis: Implications for treatment trials Annals of Neurology. 36: S86-S90. PMID 8017894 DOI: 10.1002/ana.410360719  0.6
1994 Tsuchida T, Parker KC, Turner RV, Mcfarland HF, Coligan JE, Biddison WE. Autoreactive CDS8+ T-cell responses to human myelin protein-derived peptides Proceedings of the National Academy of Sciences of the United States of America. 91: 10859-10863. PMID 7526383  0.6
1994 Voskuhl RR, Robinson ED, Segal BM, Tranquill L, Camphausen K, Albert PS, Richert JR, McFarland HF. HLA restriction and TCR usage of T lymphocytes specific for a novel candidate autoantigen, X2 MBP, in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 153: 4834-44. PMID 7525716  0.6
1994 Pelfrey CM, Trotter JL, Tranquill LR, McFarland HF. Identification of a second T cell epitope of human proteolipid protein (residues 89-106) recognized by proliferative and cytolytic CD4+ T cells from multiple sclerosis patients. Journal of Neuroimmunology. 53: 153-61. PMID 7520919 DOI: 10.1016/0165-5728(94)90025-6  0.6
1994 Utz U, Brooks JA, McFarland HF, Martin R, Biddison WE. Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 5567-71. PMID 7515505 DOI: 10.1073/pnas.91.12.5567  0.6
1994 Whitaker JN, Williams PH, Layton BA, McFarland HF, Stone LA, Smith ME, David Kachelhofer R, Bradley EL, Burgard S, Zhao G, Paty DW. Correlation of clinical features and findings on cranial magnetic resonance imaging with urinary myelin basic protein-like material in patients with multiple sclerosis Annals of Neurology. 35: 577-585. PMID 7513981 DOI: 10.1002/ana.410350511  0.6
1994 Segal BM, Raine CS, McFarlin DE, Voskuhl RR, McFarland HF. Experimental allergic encephalomyelitis induced by the peptide encoded by exon 2 of the MBP gene, a peptide implicated in remyelination. Journal of Neuroimmunology. 51: 7-19. PMID 7512579 DOI: 10.1016/0165-5728(94)90123-6  0.6
1993 Smith ME, Stone LA, Albert PS, Frank JA, Martin R, Armstrong M, Maloni H, McFarlin DE, McFarland HF. Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine - Enhancing magnetic resonance imaging lesions Annals of Neurology. 33: 480-489. PMID 8498825  0.6
1993 Katz D, Taubenberger JK, Cannella B, McFarlin DE, Raine CS, McFarland HF. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Annals of Neurology. 34: 661-9. PMID 8239560 DOI: 10.1002/ana.410340507  0.6
1993 Beall SS, Biddison WE, McFarlin DE, McFarland HF, Hood LE. Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR V beta chain locus and HLA class II genes. Journal of Neuroimmunology. 45: 53-60. PMID 8101191 DOI: 10.1016/0165-5728(93)90163-S  0.6
1993 Voskuhl RR, Martin R, Bergman C, Dalal M, Ruddle NH, McFarland HF. T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes. Autoimmunity. 15: 137-43. PMID 7692995 DOI: 10.3109/08916939309043888  0.6
1993 Martin R, Voskuhl R, Flerlage M, McFarlin DE, McFarland HF. Myelin basic protein-specific T-cell responses in identical twins discordant or concordant for multiple sclerosis Annals of Neurology. 34: 524-535. PMID 7692808  0.6
1993 Pelfrey CM, Trotter JL, Tranquill LR, McFarland HF. Identification of a novel T cell epitope of human proteolipid protein (residues 40-60) recognized by proliferative and cytolytic CD4+ T cells from multiple sclerosis patients. Journal of Neuroimmunology. 46: 33-42. PMID 7689593 DOI: 10.1016/0165-5728(93)90231-M  0.6
1993 Voskuhl RR, McFarlin DE, Tranquill LR, Deibler G, Stone R, Maloni H, McFarland HF. A novel candidate autoantigen in a multiplex family with multiple sclerosis: prevalence of T-lymphocytes specific for an MBP epitope unique to myelination Journal of Neuroimmunology. 46: 137-144. PMID 7689584 DOI: 10.1016/0165-5728(93)90243-R  0.6
1993 Utz U, Biddison WE, McFarland HF, McFarlin DE, Flerlage M, Martin R. Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis Nature. 364: 243-247. PMID 7686632  0.6
1993 Voskuhl RR, Martin R, McFarland HF. A functional basis for the association of HLA class II genes adn susceptibility to multiple sclerosis: cellular immune responses to myelin basic protein in a multiplex family Journal of Neuroimmunology. 42: 199-207. PMID 7679119 DOI: 10.1016/0165-5728(93)90011-M  0.6
1993 Voskuhl RR, McFarlin DE, Stone R, McFarland HF. T-lymphocyte recognition of a portion of myelin basic protein encoded by an exon expressed during myelination Journal of Neuroimmunology. 42: 187-191. PMID 7679118 DOI: 10.1016/0165-5728(93)90009-N  0.6
1992 Panitch HS. Outcome measures for clinical trials in multiple sclerosis. Annals of Neurology. 31: 116-7. PMID 1543345 DOI: 10.1002/ana.410310127  0.6
1992 McFarland HF, Frank JA, Albert PS, Smith ME, Martin R, Harris JO, Patronas N, Maloni H, McFarlin DE. Using gadolinium-enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis Annals of Neurology. 32: 758-766. PMID 1471866  0.6
1992 McFarland HF. Twin studies and multiple sclerosis Annals of Neurology. 32: 722-723. PMID 1471861 DOI: 10.1002/ana.410320603  0.6
1992 Martin R, McFarland HF, McFarlin DE. Immunological aspects of demyelinating diseases Annual Review of Immunology. 10: 153-187. PMID 1375472  0.6
1992 Martin R, Utz U, Coligan JE, Richert JR, Flerlage M, Robinson E, Stone R, Biddison WE, Mcfarlin DE, Mcfarland HF. Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106 Journal of Immunology. 148: 1359-1366. PMID 1371525  0.6
1992 Martin R, McFarland HF. T cell receptor usage in neurological disease: the case in multiple sclerosis Seminars in Neuroscience. 4: 243-248. DOI: 10.1016/1044-5765(92)90038-4  0.6
1991 Richert JR, Robinson ED, Martin R, McFarland HF, Hurley CK. T cell receptor gene rearrangements in the human response to myelin basic protein Annals of the New York Academy of Sciences. 636: 396-399. PMID 1724363 DOI: 10.1111/j.1749-6632.1991.tb33477.x  0.6
1991 Martin R, Howell MD, Jaraquemada D, Flerlage M, Richert J, Brostoff S, Long EO, McFarlin DE, McFarland HF. A myelin basic protein peptide is recognized by cytotoxic t cells in the context of four HLA-DR types associated with multiple sclerosis Journal of Experimental Medicine. 173: 19-24. PMID 1702137  0.6
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