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Year Citation  Score
2024 Stellingwerff MD, Al-Saady ML, Chan KS, Dvorak A, Marques JP, Kolind S, Schoenmakers DH, van Voorst R, Roosendaal SD, Barkhof F, Wolf NI, Berkhof J, Pouwels PJW, van der Knaap MS. Quantitative MRI distinguishes different leukodystrophies and correlates with clinical measures. European Radiology. PMID 39320477 DOI: 10.1007/s00330-024-11089-5  0.486
2024 Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, ... ... Barkhof F, et al. Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia. Neurology. 103: e209801. PMID 39288341 DOI: 10.1212/WNL.0000000000209801  0.658
2024 Lorenzini L, Collij LE, Tesi N, Vilor-Tejedor N, Ingala S, Blennow K, Foley C, Frisoni GB, Haller S, Holstege H, van der van der Lee S, Martinez-Lage P, Marioni RE, McCartney DL, O' Brien J, ... ... Barkhof F, et al. Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39073684 DOI: 10.1002/alz.14096  0.65
2024 Ulugut H, Bertoux M, Younes K, Montembeault M, Fumagalli GG, Samanci B, Illán-Gala I, Kuchcinski G, Leroy M, Thompson JC, Kobylecki C, Santillo AF, Englund E, Waldö ML, Riedl L, ... ... Barkhof F, et al. Clinical recognition of frontotemporal dementia with right anterior temporal predominance: A multicenter retrospective cohort study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38982845 DOI: 10.1002/alz.14076  0.329
2024 Mastenbroek SE, Sala A, Vállez García D, Shekari M, Salvadó G, Lorenzini L, Pieperhoff L, Wink AM, Lopes Alves I, Wolz R, Ritchie C, Boada M, Visser PJ, Bucci M, Farrar G, ... ... Barkhof F, et al. Continuous β-Amyloid CSF/PET Imbalance Model to Capture Alzheimer Disease Heterogeneity. Neurology. 103: e209419. PMID 38862136 DOI: 10.1212/WNL.0000000000209419  0.601
2024 Tranfa M, Lorenzini L, Collij LE, Vállez García D, Ingala S, Pontillo G, Pieperhoff L, Maranzano A, Wolz R, Haller S, Blennow K, Frisoni G, Sudre CH, Chételat G, Ewers M, ... ... Barkhof F, et al. Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure. Annals of Clinical and Translational Neurology. PMID 38757392 DOI: 10.1002/acn3.52071  0.634
2024 van der Knaap MS, Barkhof F, Rossi A. Obituary: Jacob Valk. Neuroradiology. 66: 1063-1064. PMID 38735023 DOI: 10.1007/s00234-024-03376-1  0.303
2024 Bollack A, Collij LE, García DV, Shekari M, Altomare D, Payoux P, Dubois B, Grau-Rivera O, Boada M, Marquié M, Nordberg A, Walker Z, Scheltens P, Schöll M, Wolz R, ... ... Barkhof F, et al. Investigating reliable amyloid accumulation in Centiloids: Results from the AMYPAD Prognostic and Natural History Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38574374 DOI: 10.1002/alz.13761  0.31
2024 Hönig M, Altomare D, Caprioglio C, Collij L, Barkhof F, Van Berckel B, Scheltens P, Farrar G, Battle MR, Theis H, Giehl K, Bischof GN, Garibotto V, Molinuevo JLL, Grau-Rivera O, et al. Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease. Neurology. 102: e208053. PMID 38377442 DOI: 10.1212/WNL.0000000000208053  0.396
2024 Koubiyr I, Krijnen EA, Eijlers AJC, Dekker I, Hulst HE, Uitdehaag BMJ, Barkhof F, Geurts JJG, Schoonheim MM. Longitudinal fibre-specific white matter damage predicts cognitive decline in multiple sclerosis. Brain Communications. 6: fcae018. PMID 38344654 DOI: 10.1093/braincomms/fcae018  0.539
2023 Stellingwerff MD, Al-Saady ML, Chan KS, Dvorak A, Marques JP, Kolind S, Roosendaal SD, Wolf NI, Barkhof F, van der Knaap MS, Pouwels PJW. Applicability of multiple quantitative magnetic resonance methods in genetic brain white matter disorders. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 37925602 DOI: 10.1111/jon.13167  0.483
2023 Bader I, Bader I, Lopes Alves I, Vállez García D, Vellas B, Dubois B, Boada M, Marquié M, Altomare D, Scheltens P, Vandenberghe R, Hanseeuw B, Schöll M, Frisoni GB, Jessen F, ... ... Barkhof F, et al. Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study. Alzheimer's Research & Therapy. 15: 189. PMID 37919783 DOI: 10.1186/s13195-023-01332-4  0.371
2023 Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, ... ... Barkhof F, et al. Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning. Genome Medicine. 15: 79. PMID 37794492 DOI: 10.1186/s13073-023-01233-z  0.351
2023 Coomans EM, de Koning LA, Rikken RM, Verfaillie SCJ, Visser D, den Braber A, Tomassen J, van de Beek M, Collij LE, Lemstra AW, Windhorst AD, Barkhof F, Golla SSV, Visser PJ, Scheltens P, et al. Performance of a [F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia With Lewy Bodies. Neurology. 101: e1850-e1862. PMID 37748892 DOI: 10.1212/WNL.0000000000207794  0.361
2023 Bollack A, Markiewicz PJ, Wink AM, Prosser L, Lilja J, Bourgeat P, Schott JM, Coath W, Collij LE, Pemberton HG, Farrar G, Barkhof F, Cash DM. Evaluation of novel data-driven metrics of amyloid β deposition for longitudinal PET studies. Neuroimage. 120313. PMID 37595816 DOI: 10.1016/j.neuroimage.2023.120313  0.574
2023 van Amerongen S, Kamps S, Kaijser KKM, Pijnenburg YAL, Scheltens P, Teunissen CE, Barkhof F, Ossenkoppele R, Rozemuller AJM, Stern RA, Hoozemans JJM, Vijverberg EGB. Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature. Acta Neuropathologica Communications. 11: 77. PMID 37161501 DOI: 10.1186/s40478-023-01572-3  0.407
2023 Altomare D, Barkhof F, Caprioglio C, Collij LE, Scheltens P, Lopes Alves I, Bouwman F, Berkhof J, van Maurik IS, Garibotto V, Moro C, Delrieu J, Payoux P, Saint-Aubert L, Hitzel A, et al. Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial. Jama Neurology. PMID 37155177 DOI: 10.1001/jamaneurol.2023.0997  0.334
2023 Lorenzini L, Ingala S, Collij LE, Wottschel V, Haller S, Blennow K, Frisoni G, Chételat G, Payoux P, Lage-Martinez P, Ewers M, Waldman A, Wardlaw J, Ritchie C, Gispert JD, ... ... Barkhof F, et al. Eigenvector centrality dynamics are related to Alzheimer's disease pathological changes in non-demented individuals. Brain Communications. 5: fcad088. PMID 37151225 DOI: 10.1093/braincomms/fcad088  0.672
2023 Stellingwerff MD, Pouwels PJW, Roosendaal SD, Barkhof F, van der Knaap MS. Quantitative MRI in leukodystrophies. Neuroimage. Clinical. 38: 103427. PMID 37150021 DOI: 10.1016/j.nicl.2023.103427  0.464
2023 Frisoni GB, Altomare D, Ribaldi F, Villain N, Brayne C, Mukadam N, Abramowicz M, Barkhof F, Berthier M, Bieler-Aeschlimann M, Blennow K, Brioschi Guevara A, Carrera E, Chételat G, Csajka C, et al. Dementia prevention in memory clinics: recommendations from the European task force for brain health services. The Lancet Regional Health. Europe. 26: 100576. PMID 36895446 DOI: 10.1016/j.lanepe.2022.100576  0.353
2023 Coomans EM, Tomassen J, Ossenkoppele R, Tijms BM, Lorenzini L, Ten Kate M, Collij LE, Heeman F, Rikken RM, van der Landen SM, den Hollander ME, Golla SSV, Yaqub M, Windhorst AD, Barkhof F, et al. Genetically identical twin-pair difference models support the amyloid cascade hypothesis. Brain : a Journal of Neurology. PMID 36892415 DOI: 10.1093/brain/awad077  0.337
2023 Dijsselhof MBJ, Barboure M, Stritt M, Nordhøy W, Wink AM, Beck D, Westlye LT, Cole JH, Barkhof F, Mutsaerts HJMM, Petr J. The value of arterial spin labelling perfusion MRI in brain age prediction. Human Brain Mapping. PMID 36852443 DOI: 10.1002/hbm.26242  0.592
2023 den Braber A, Verberk IMW, Tomassen J, den Dulk B, Stoops E, Dage JL, Collij LE, Barkhof F, Willemsen G, Nivard MG, van Berckel BNM, Scheltens P, Visser PJ, de Geus EJC, Teunissen CE. Plasma biomarkers predict amyloid pathology in cognitively normal monozygotic twins after 10 years. Brain Communications. 5: fcad024. PMID 36824390 DOI: 10.1093/braincomms/fcad024  0.347
2023 van 't Hooft JJ, Pelkmans W, Tomassen J, Smits C, Legdeur N, den Braber A, Barkhof F, van Berckel B, Yaqub M, Scheltens P, Pijnenburg YA, Visser PJ, Tijms BM. Distinct disease mechanisms may underlie cognitive decline related to hearing loss in different age groups. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 36639225 DOI: 10.1136/jnnp-2022-329726  0.324
2023 Caprioglio C, Ribaldi F, Visser LNC, Minguillon C, Collij LE, Grau-Rivera O, Zeyen P, Molinuevo JL, Gispert JD, Garibotto V, Moro C, Walker Z, Edison P, Demonet JF, Barkhof F, et al. Analysis of Psychological Symptoms Following Disclosure of Amyloid-Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline. Jama Network Open. 6: e2250921. PMID 36637820 DOI: 10.1001/jamanetworkopen.2022.50921  0.375
2022 Küçükali F, Neumann A, Van Dongen J, De Pooter T, Joris G, De Rijk P, Ohlei O, Dobricic V, Bos I, Vos SJB, Engelborghs S, De Roeck E, Vandenberghe R, Gabel S, Meersmans K, ... ... Barkhof F, et al. Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36464806 DOI: 10.1002/alz.12842  0.347
2022 Leijenaar JF, Ingala S, Sudre CH, Mutsaerts HM, Leeuwis AE, van der Flier WM, Scheltens P, Weinstein HC, Barkhof F, van Gerven J, Groeneveld GJ, Prins ND. Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI. Cerebral Circulation - Cognition and Behavior. 3: 100128. PMID 36324417 DOI: 10.1016/j.cccb.2022.100128  0.404
2022 Boomsma JM, Exalto LG, Barkhof F, Leeuwis AE, Prins ND, Scheltens P, Teunissen CE, Weinstein HC, Biessels GJ, van der Flier WM. Vascular Cognitive Impairment and cognitive decline; a longitudinal study comparing different types of vascular brain injury - The TRACE-VCI study. Cerebral Circulation - Cognition and Behavior. 3: 100141. PMID 36324410 DOI: 10.1016/j.cccb.2022.100141  0.357
2022 Carotenuto A, Valsasina P, Schoonheim MM, Geurts JJ, Barkhof F, Gallo A, Tedeschi G, Tommasin S, Pantano P, Filippi M, Rocca MA. Investigating Functional Network Abnormalities and Associations With Disability in Multiple Sclerosis. Neurology. PMID 36096690 DOI: 10.1212/WNL.0000000000201264  0.514
2022 Ebenau JL, Visser D, Verfaillie SCJ, Timmers T, van Leeuwenstijn MSSA, Kate MT, Windhorst AD, Barkhof F, Scheltens P, Prins ND, Boellaard R, van der Flier WM, van Berckel BNM. Cerebral blood flow, amyloid burden, and cognition in cognitively normal individuals. European Journal of Nuclear Medicine and Molecular Imaging. PMID 36071221 DOI: 10.1007/s00259-022-05958-8  0.37
2022 Ebenau JL, Visser D, Kroeze LA, van Leeuwenstijn MSSA, van Harten AC, Windhorst AD, Golla SVS, Boellaard R, Scheltens P, Barkhof F, van Berckel BNM, van der Flier WM. Longitudinal change in ATN biomarkers in cognitively normal individuals. Alzheimer's Research & Therapy. 14: 124. PMID 36057616 DOI: 10.1186/s13195-022-01069-6  0.37
2022 van Amerongen S, Caton DK, Ossenkoppele R, Barkhof F, Pouwels PJW, Teunissen CE, Rozemuller AJM, Hoozemans JJM, Pijnenburg YAL, Scheltens P, Vijverberg EGB. Rationale and design of the "NEurodegeneration: Traumatic brain injury as Origin of the Neuropathology (NEwTON)" study: a prospective cohort study of individuals at risk for chronic traumatic encephalopathy. Alzheimer's Research & Therapy. 14: 119. PMID 36050790 DOI: 10.1186/s13195-022-01059-8  0.339
2022 Mank A, van Maurik IS, Rijnhart JJM, Bakker ED, Bouteloup V, Le Scouarnec L, Teunissen CE, Barkhof F, Scheltens P, Berkhof J, van der Flier WM. Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer's disease. Alzheimer's Research & Therapy. 14: 110. PMID 35932034 DOI: 10.1186/s13195-022-01053-0  0.351
2022 Lorenzini L, Ingala S, Wink AM, Kuijer JPA, Wottschel V, Dijsselhof M, Sudre CH, Haller S, Molinuevo JL, Gispert JD, Cash DM, Thomas DL, Vos SB, Prados F, Petr J, ... ... Barkhof F, et al. The Open-Access European Prevention of Alzheimer's Dementia (EPAD) MRI dataset and processing workflow. Neuroimage. Clinical. 35: 103106. PMID 35839659 DOI: 10.1016/j.nicl.2022.103106  0.636
2022 Lorenzini L, Ansems LT, Lopes Alves I, Ingala S, Vállez García D, Tomassen J, Sudre C, Salvadó G, Shekari M, Operto G, Brugulat-Serrat A, Sánchez-Benavides G, Ten Kate M, Tijms B, Wink AM, ... ... Barkhof F, et al. Regional associations of white matter hyperintensities and early cortical amyloid pathology. Brain Communications. 4: fcac150. PMID 35783557 DOI: 10.1093/braincomms/fcac150  0.633
2022 Prouskas SE, Schoonheim MM, Huiskamp M, Steenwijk MD, Gehring K, Barkhof F, de Jong BA, Sitskoorn MM, Geurts JJ, Hulst HE. A randomized trial predicting response to cognitive rehabilitation in multiple sclerosis: Is there a window of opportunity? Multiple Sclerosis (Houndmills, Basingstoke, England). 13524585221103134. PMID 35765748 DOI: 10.1177/13524585221103134  0.475
2022 Altomare D, Collij L, Caprioglio C, Scheltens P, van Berckel BNM, Alves IL, Berkhof J, de Gier Y, Garibotto V, Moro C, Poitrine L, Delrieu J, Payoux P, Saint-Aubert L, Molinuevo JL, ... ... Barkhof F, et al. Description of a European memory clinic cohort undergoing amyloid-PET: The AMYPAD Diagnostic and Patient Management Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35715930 DOI: 10.1002/alz.12696  0.318
2022 Delvenne A, Gobom J, Tijms B, Bos I, Reus LM, Dobricic V, Kate MT, Verhey F, Ramakers I, Scheltens P, Teunissen CE, Vandenberghe R, Schaeverbeke J, Gabel S, Popp J, ... ... Barkhof F, et al. Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35698882 DOI: 10.1002/alz.12713  0.391
2022 Dubbelman MA, Verrijp M, Terwee CB, Jutten RJ, Postema MC, Barkhof F, Berckel BNM, Gillissen F, Teeuwen V, Teunissen C, van de Flier WM, Scheltens P, Sikkes SAM. Pursuing Clinical Meaningfulness: Determining the Minimal Important Change of Everyday Functioning in Dementia. Neurology. PMID 35641309 DOI: 10.1212/WNL.0000000000200781  0.336
2022 Broeders TAA, Douw L, Eijlers AJC, Dekker I, Uitdehaag BMJ, Barkhof F, Hulst HE, Vinkers CH, Geurts JJG, Schoonheim MM. A more unstable resting-state functional network in cognitively declining multiple sclerosis. Brain Communications. 4: fcac095. PMID 35620116 DOI: 10.1093/braincomms/fcac095  0.518
2022 Homann J, Osburg T, Ohlei O, Dobricic V, Deecke L, Bos I, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, Blin O, Richardson JC, Bordet R, ... ... Barkhof F, et al. Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset. Frontiers in Aging Neuroscience. 14: 840651. PMID 35386118 DOI: 10.3389/fnagi.2022.840651  0.401
2022 van Loenhoud AC, Groot C, Bocancea DI, Barkhof F, Teunissen C, Scheltens P, van de Flier WM, Ossenkoppele R. Association of Education and Intracranial Volume With Cognitive Trajectories and Mortality Rates Across the Alzheimer Disease Continuum. Neurology. 98: e1679-e1691. PMID 35314498 DOI: 10.1212/WNL.0000000000200116  0.386
2022 Pelkmans W, Vromen EM, Dicks E, Scheltens P, Teunissen CE, Barkhof F, van der Flier WM, Tijms BM. Grey matter network markers identify individuals with prodromal Alzheimer's disease who will show rapid clinical decline. Brain Communications. 4: fcac026. PMID 35310828 DOI: 10.1093/braincomms/fcac026  0.446
2022 Collij LE, Salvadó G, Wottschel V, Mastenbroek SE, Schoenmakers P, Heeman F, Aksman L, Wink AM, Berckel BNM, van de Flier WM, Scheltens P, Visser PJ, Barkhof F, Haller S, Gispert JD, et al. Spatial-Temporal Patterns of Amyloid-β Accumulation: A Subtype and Stage Inference Model Analysis. Neurology. PMID 35292558 DOI: 10.1212/WNL.0000000000200148  0.614
2022 Verhaar BJH, Hendriksen HMA, de Leeuw FA, Doorduijn AS, van Leeuwenstijn M, Teunissen CE, Barkhof F, Scheltens P, Kraaij R, van Duijn CM, Nieuwdorp M, Muller M, van der Flier WM. Gut Microbiota Composition Is Related to AD Pathology. Frontiers in Immunology. 12: 794519. PMID 35173707 DOI: 10.3389/fimmu.2021.794519  0.383
2022 Neumann A, Küçükali F, Bos I, Vos SJB, Engelborghs S, De Pooter T, Joris G, De Rijk P, De Roeck E, Tsolaki M, Verhey F, Martinez-Lage P, Tainta M, Frisoni G, Blin O, ... ... Barkhof F, et al. Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation. Molecular Psychiatry. PMID 35173266 DOI: 10.1038/s41380-022-01437-6  0.32
2022 Ebenau JL, Pelkmans W, Verberk IMW, Verfaillie S, van den Bosch KA, van Leeuwenstijn M, Collij L, Scheltens P, Prins N, Barkhof F, van Berckel B, Teunissen CE, Van der Flier WM. Association of CSF, Plasma, and Imaging Markers of Neurodegeneration With Clinical Progression in People With Subjective Cognitive Decline. Neurology. PMID 35110378 DOI: 10.1212/WNL.0000000000200035  0.373
2022 van de Beek M, Ooms FAH, Ebenau JL, Barkhof F, Scheltens P, Teunissen CE, van Harten AC, van der Flier WM, Lemstra AW. Association of the ATN Research Framework With Clinical Profile, Ccognitive Decline, and Mortality in Patients With Dementia With Lewy Bodies. Neurology. PMID 35074893 DOI: 10.1212/WNL.0000000000200048  0.362
2022 Coomans EM, Tomassen J, Ossenkoppele R, Golla SSV, den Hollander M, Collij LE, Weltings E, van der Landen S, Wolters EE, Windhorst AD, Barkhof F, de Geus EJC, Scheltens P, Visser PJ, van Berckel BNM, et al. Genetically identical twins show comparable tau PET load and spatial distribution. Brain : a Journal of Neurology. PMID 35022652 DOI: 10.1093/brain/awac004  0.308
2021 Salvadó G, Ferreira D, Operto G, Cumplido-Mayoral I, Arenaza-Urquijo EM, Cacciaglia R, Falcon C, Vilor-Tejedor N, Minguillon C, Groot C, van der Flier WM, Barkhof F, Scheltens P, Ossenkoppele R, Kern S, et al. The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34877786 DOI: 10.1002/alz.12487  0.377
2021 Ranson JM, Rittman T, Hayat S, Brayne C, Jessen F, Blennow K, van Duijn C, Barkhof F, Tang E, Mummery CJ, Stephan BCM, Altomare D, Frisoni GB, Ribaldi F, Molinuevo JL, et al. Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6. Alzheimer's Research & Therapy. 13: 169. PMID 34635138 DOI: 10.1186/s13195-021-00895-4  0.321
2021 Ingala S, Tomassen J, Collij LE, Prent N, van 't Ent D, Ten Kate M, Konijnenberg E, Yaqub M, Scheltens P, de Geus EJC, Teunissen CE, Tijms B, Wink AM, Barkhof F, van Berckel BNM, et al. Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals. Brain Communications. 3: fcab201. PMID 34617016 DOI: 10.1093/braincomms/fcab201  0.649
2021 Ebenau JL, van der Lee SJ, Hulsman M, Tesi N, Jansen IE, Verberk IMW, van Leeuwenstijn M, Teunissen CE, Barkhof F, Prins ND, Scheltens P, Holstege H, van Berckel BNM, van der Flier WM. Risk of dementia in ε4 carriers is mitigated by a polygenic risk score. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12229. PMID 34541285 DOI: 10.1002/dad2.12229  0.338
2021 Collij LE, Mastenbroek SE, Salvadó G, Wink AM, Visser PJ, Barkhof F, van Berckel BNM, Lopes Alves I. Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12216. PMID 34368416 DOI: 10.1002/dad2.12216  0.602
2021 Ulugut H, Dijkstra AA, Scarioni M, Barkhof F, Scheltens P, Rozemuller AJM, Pijnenburg YAL. Right temporal variant frontotemporal dementia is pathologically heterogeneous: a case-series and a systematic review. Acta Neuropathologica Communications. 9: 131. PMID 34344452 DOI: 10.1186/s40478-021-01229-z  0.332
2021 Ulugut H, Stek S, Wagemans LEE, Jutten RJ, Keulen MA, Bouwman FH, Prins ND, Lemstra AW, Krudop W, Teunissen CE, van Berckel BNM, Ossenkoppele R, Barkhof F, van der Flier WM, Scheltens P, et al. The natural history of primary progressive aphasia: beyond aphasia. Journal of Neurology. PMID 34216263 DOI: 10.1007/s00415-021-10689-1  0.315
2021 Stellingwerff MD, Al-Saady ML, van de Brug T, Barkhof F, Pouwels PJW, van der Knaap MS. MRI Natural History of the Leukodystrophy Vanishing White Matter. Radiology. 210110. PMID 34184934 DOI: 10.1148/radiol.2021210110  0.474
2021 Groot C, Risacher SL, Chen JQA, Dicks E, Saykin AJ, Mac Donald CL, Mez J, Trittschuh EH, Mukherjee S, Barkhof F, Scheltens P, van der Flier WM, Ossenkoppele R, Crane PK. Differential trajectories of hypometabolism across cognitively-defined Alzheimer's disease subgroups. Neuroimage. Clinical. 31: 102725. PMID 34153688 DOI: 10.1016/j.nicl.2021.102725  0.376
2021 Huiskamp M, Eijlers AJC, Broeders TAA, Pasteuning J, Dekker I, Uitdehaag BMJ, Barkhof F, Wink AM, Geurts JJG, Hulst HE, Schoonheim MM. Longitudinal Network Changes and Conversion to Cognitive Impairment in Multiple Sclerosis. Neurology. PMID 34099528 DOI: 10.1212/WNL.0000000000012341  0.698
2021 Hong S, Dobricic V, Ohlei O, Bos I, Vos SJB, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, ... ... Barkhof F, et al. TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33991015 DOI: 10.1002/alz.12330  0.344
2021 Granziera C, Wuerfel J, Barkhof F, Calabrese M, De Stefano N, Enzinger C, Evangelou N, Filippi M, Geurts JJG, Reich DS, Rocca MA, Ropele S, Rovira À, Sati P, Toosy AT, et al. Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis. Brain : a Journal of Neurology. PMID 33970206 DOI: 10.1093/brain/awab029  0.537
2021 Groot C, Grothe MJ, Mukherjee S, Jelistratova I, Jansen I, van Loenhoud AC, Risacher SL, Saykin AJ, Mac Donald CL, Mez J, Trittschuh EH, Gryglewski G, Lanzenberger R, Pijnenburg YAL, Barkhof F, et al. Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer's disease subgroups. Neuroimage. Clinical. 30: 102660. PMID 33895633 DOI: 10.1016/j.nicl.2021.102660  0.395
2021 van Engelen ME, Rozemuller AJM, Ulugut Erkoyun H, Groot C, Fieldhouse JLP, Koene T, Ossenkoppele R, Gossink FT, Krudop WA, Vijverberg EGB, Dols A, Barkhof F, Berckel BNMV, Scheltens P, Brain Bank N, et al. The bvFTD phenocopy syndrome: a case study supported by repeated MRI, [F]FDG-PET and pathological assessment. Neurocase. 1-9. PMID 33881963 DOI: 10.1080/13554794.2021.1905855  0.341
2021 Haider L, Prados F, Chung K, Goodkin O, Kanber B, Sudre C, Yiannakas M, Samson RS, Mangesius S, Thompson AJ, Gandini Wheeler-Kingshott CAM, Ciccarelli O, Chard DT, Barkhof F. Cortical involvement determines impairment 30 years after a clinically isolated syndrome. Brain : a Journal of Neurology. PMID 33880511 DOI: 10.1093/brain/awab033  0.31
2021 Schoonheim MM, Pinter D, Prouskas SE, Broeders TA, Pirpamer L, Khalil M, Ropele S, Uitdehaag BM, Barkhof F, Enzinger C, Geurts JJ. Disability in multiple sclerosis is related to thalamic connectivity and cortical network atrophy. Multiple Sclerosis (Houndmills, Basingstoke, England). 13524585211008743. PMID 33870779 DOI: 10.1177/13524585211008743  0.491
2021 Collij LE, Ingala S, Top H, Wottschel V, Stickney KE, Tomassen J, Konijnenberg E, Ten Kate M, Sudre C, Lopes Alves I, Yaqub MM, Wink AM, Van 't Ent D, Scheltens P, van Berckel BNM, ... ... Barkhof F, et al. White matter microstructure disruption in early stage amyloid pathology. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12124. PMID 33816751 DOI: 10.1002/dad2.12124  0.666
2021 Ingala S, De Boer C, Masselink LA, Vergari I, Lorenzini L, Blennow K, Chételat G, Di Perri C, Ewers M, van der Flier WM, Fox NC, Gispert JD, Haller S, Molinuevo JL, Muniz-Terrera G, ... ... Barkhof F, et al. Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33811742 DOI: 10.1002/alz.12292  0.642
2021 Shi L, Winchester LM, Westwood S, Baird AL, Anand SN, Buckley NJ, Hye A, Ashton NJ, Bos I, Vos SJB, Kate MT, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, ... ... Barkhof F, et al. Replication study of plasma proteins relating to Alzheimer's pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33792144 DOI: 10.1002/alz.12322  0.348
2021 Collij LE, Salvadó G, Shekari M, Alves IL, Reimand J, Wink AM, Zwan M, Niñerola-Baizán A, Perissinotti A, Scheltens P, Ikonomovic MD, Smith APL, Farrar G, Molinuevo JL, Barkhof F, et al. Visual assessment of [F]flutemetamol PET images can detect early amyloid pathology and grade its extent. European Journal of Nuclear Medicine and Molecular Imaging. PMID 33615397 DOI: 10.1007/s00259-020-05174-2  0.627
2021 Chard DT, Alahmadi AAS, Audoin B, Charalambous T, Enzinger C, Hulst HE, Rocca MA, Rovira À, Sastre-Garriga J, Schoonheim MM, Tijms B, Tur C, Gandini Wheeler-Kingshott CAM, Wink AM, Ciccarelli O, ... Barkhof F, et al. Mind the gap: from neurons to networks to outcomes in multiple sclerosis. Nature Reviews. Neurology. PMID 33437067 DOI: 10.1038/s41582-020-00439-8  0.626
2021 Erkoyun HU, van der Lee SJ, Nijmeijer B, Spaendonk RV, Nelissen A, Scarioni M, Dijkstra A, Samancı B, Gürvit H, Yıldırım Z, Tepgeç F, Bilgic B, Barkhof F, Rozemuller A, van der Flier WM, et al. The Right Temporal Variant of Frontotemporal Dementia is Not Genetically Sporadic: A Case Series. Journal of Alzheimer's Disease : Jad. PMID 33427744 DOI: 10.3233/JAD-201191  0.301
2021 Pelkmans W, Legdeur N, Ten Kate M, Barkhof F, Yaqub MM, Holstege H, van Berckel BNM, Scheltens P, van der Flier WM, Visser PJ, Tijms BM. Amyloid-β, cortical thickness, and subsequent cognitive decline in cognitively normal oldest-old. Annals of Clinical and Translational Neurology. PMID 33421355 DOI: 10.1002/acn3.51273  0.36
2021 van Maurik IS, Rhodius-Meester HFM, Teunissen CE, Scheltens P, Barkhof F, Palmqvist S, Hansson O, van der Flier WM, Berkhof J. Biomarker testing in MCI patients-deciding who to test. Alzheimer's Research & Therapy. 13: 14. PMID 33413634 DOI: 10.1186/s13195-020-00763-7  0.356
2020 Tijms BM, Gobom J, Reus L, Jansen I, Hong S, Dobricic V, Kilpert F, Ten Kate M, Barkhof F, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, et al. Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics. Brain : a Journal of Neurology. 143: 3776-3792. PMID 33439986 DOI: 10.1093/brain/awaa325  0.412
2020 Dekker I, Schoonheim MM, Venkatraghavan V, Eijlers AJC, Brouwer I, Bron EE, Klein S, Wattjes MP, Wink AM, Geurts JJG, Uitdehaag BMJ, Oxtoby NP, Alexander DC, Vrenken H, Killestein J, ... Barkhof F, et al. The sequence of structural, functional and cognitive changes in multiple sclerosis. Neuroimage. Clinical. 29: 102550. PMID 33418173 DOI: 10.1016/j.nicl.2020.102550  0.698
2020 Dicks E, Vermunt L, van der Flier WM, Barkhof F, Scheltens P, Tijms BM. Grey matter network trajectories across the Alzheimer's disease continuum and relation to cognition. Brain Communications. 2: fcaa177. PMID 33376987 DOI: 10.1093/braincomms/fcaa177  0.405
2020 Hong S, Prokopenko D, Dobricic V, Kilpert F, Bos I, Vos SJB, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Cleynen I, Gabel S, Schaeverbeke J, Scheltens P, Teunissen CE, ... ... Barkhof F, et al. Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset. Translational Psychiatry. 10: 403. PMID 33223526 DOI: 10.1038/s41398-020-01074-z  0.358
2020 Singleton EH, Pijnenburg YAL, Sudre CH, Groot C, Kochova E, Barkhof F, La Joie R, Rosen HJ, Seeley WW, Miller B, Cardoso MJ, Papma J, Scheltens P, Rabinovici GD, Ossenkoppele R. Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease. Alzheimer's Research & Therapy. 12: 148. PMID 33189136 DOI: 10.1186/s13195-020-00717-z  0.345
2020 Chételat G, Arbizu J, Barthel H, Garibotto V, Law I, Morbelli S, van de Giessen E, Agosta F, Barkhof F, Brooks DJ, Carrillo MC, Dubois B, Fjell AM, Frisoni GB, Hansson O, et al. Amyloid-PET and F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias. The Lancet. Neurology. 19: 951-962. PMID 33098804 DOI: 10.1016/S1474-4422(20)30314-8  0.322
2020 Leeuwis AE, Hooghiemstra AM, Bron EE, Kuipers S, Oudeman EA, Kalay T, Brunner-La Rocca HP, Kappelle LJ, van Oostenbrugge RJ, Greving JP, Niessen WJ, van Buchem MA, van Osch MJP, van Rossum AC, Prins ND, ... ... Barkhof F, et al. Cerebral blood flow and cognitive functioning in patients with disorders along the heart-brain axis: Cerebral blood flow and the heart-brain axis. Alzheimer's & Dementia (New York, N. Y.). 6: e12034. PMID 32995468 DOI: 10.1002/Trc2.12034  0.337
2020 Verberk IMW, Thijssen E, Koelewijn J, Mauroo K, Vanbrabant J, de Wilde A, Zwan MD, Verfaillie SCJ, Ossenkoppele R, Barkhof F, van Berckel BNM, Scheltens P, van der Flier WM, Stoops E, Vanderstichele HM, et al. Combination of plasma amyloid beta and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology. Alzheimer's Research & Therapy. 12: 118. PMID 32988409 DOI: 10.1186/s13195-020-00682-7  0.341
2020 Moccia M, van de Pavert S, Eshaghi A, Haider L, Pichat J, Yiannakas M, Ourselin S, Wang Y, Wheeler-Kingshott C, Thompson A, Barkhof F, Ciccarelli O. Pathological correlates of the magnetization transfer ratio in multiple sclerosis. Neurology. PMID 32938787 DOI: 10.1212/Wnl.0000000000010909  0.335
2020 Legdeur N, Badissi M, Yaqub M, Beker N, Sudre CH, Ten Kate M, Gordon MF, Novak G, Barkhof F, van Berckel BNM, Holstege H, Muller M, Scheltens P, Maier AB, Visser PJ. What determines cognitive functioning in the oldest-old? The EMIF-AD 90+ Study. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences. PMID 32898275 DOI: 10.1093/Geronb/Gbaa152  0.46
2020 Bouman PM, Steenwijk MD, Pouwels PJW, Schoonheim MM, Barkhof F, Jonkman LE, Geurts JJG. Histopathology-validated recommendations for cortical lesion imaging in multiple sclerosis. Brain : a Journal of Neurology. PMID 32889535 DOI: 10.1093/Brain/Awaa233  0.555
2020 de Leeuw FA, Karamujić-Čomić H, Tijms BM, Peeters CFW, Kester MI, Scheltens P, Ahmad S, Vojinovic D, Adams HHH, Hankemeier T, Bos D, van der Lugt A, Vernooij MW, Ikram MA, Amin N, ... Barkhof F, et al. Circulating metabolites are associated with brain atrophy and white matter hyperintensities. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32886448 DOI: 10.1002/Alz.12180  0.47
2020 Exalto LG, Boomsma JMF, Babapour Mofrad R, Barkhof F, Groeneveld ON, Heinen R, Kuijf HJ, Leeuwis AE, Prins ND, Biessels GJ, Vd Flier WM. Sex differences in memory clinic patients with possible vascular cognitive impairment. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12090. PMID 32875057 DOI: 10.1002/Dad2.12090  0.313
2020 Shi L, Winchester LM, Liu BY, Killick R, Ribe EM, Westwood S, Baird AL, Buckley NJ, Hong S, Dobricic V, Kilpert F, Franke A, Kiddle S, Sattlecker M, Dobson R, ... ... Barkhof F, et al. Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology. Journal of Alzheimer's Disease : Jad. PMID 32831200 DOI: 10.3233/Jad-200208  0.435
2020 Ulugut Erkoyun H, Groot C, Heilbron R, Nelissen A, van Rossum J, Jutten R, Koene T, van der Flier WM, Wattjes MP, Scheltens P, Ossenkoppele R, Barkhof F, Pijnenburg Y. A clinical-radiological framework of the right temporal variant of frontotemporal dementia. Brain : a Journal of Neurology. PMID 32830218 DOI: 10.1093/Brain/Awaa225  0.484
2020 Gerdes LA, Janoschka C, Eveslage M, Mannig B, Wirth T, Schulte-Mecklenbeck A, Lauks S, Glau L, Gross CC, Tolosa E, Flierl-Hecht A, Ertl-Wagner B, Barkhof F, Meuth SG, Kümpfel T, et al. Immune signatures of prodromal multiple sclerosis in monozygotic twins. Proceedings of the National Academy of Sciences of the United States of America. 117: 21546-21556. PMID 32817525 DOI: 10.1073/Pnas.2003339117  0.308
2020 Frisoni GB, Molinuevo JL, Altomare D, Carrera E, Barkhof F, Berkhof J, Delrieu J, Dubois B, Kivipelto M, Nordberg A, Schott JM, van der Flier WM, Vellas B, Jessen F, Scheltens P, et al. Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32815289 DOI: 10.1002/Alz.12132  0.443
2020 Verhaar BJH, de Leeuw FA, Doorduijn AS, Fieldhouse JLP, van de Rest O, Teunissen CE, van Berckel BNM, Barkhof F, Visser M, de van der Schueren MAE, Scheltens P, Kester MI, Muller M, van der Flier WM. Nutritional status and structural brain changes in Alzheimer's disease: The NUDAD project. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12063. PMID 32793798 DOI: 10.1002/Dad2.12063  0.505
2020 Ingala S, Mazzai L, Sudre CH, Salvadó G, Brugulat-Serrat A, Wottschel V, Falcon C, Operto G, Tijms B, Gispert JD, Molinuevo JL, Barkhof F. The relation between APOE genotype and cerebral microbleeds in cognitively unimpaired middle- and old-aged individuals. Neurobiology of Aging. 95: 104-114. PMID 32791423 DOI: 10.1016/J.Neurobiolaging.2020.06.015  0.365
2020 Boomsma JMF, Exalto LG, Barkhof F, Chen CLH, Hilal S, Leeuwis AE, Prins ND, Saridin FN, Scheltens P, Teunissen CE, Verwer JH, Weinstein HC, van der Flier WM, Biessels GJ. Prediction of poor clinical outcome in vascular cognitive impairment: TRACE-VCI study. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12077. PMID 32789162 DOI: 10.1002/Dad2.12077  0.44
2020 Mofrad RB, Tijms BM, Scheltens P, Barkhof F, van der Flier WM, Am Sikkes S, Teunissen CE. Sex differences in CSF biomarkers vary by Alzheimer's disease stage and APOE ε4 genotype. Neurology. PMID 32788242 DOI: 10.1212/Wnl.0000000000010629  0.423
2020 Geraldes R, Juryńczyk M, Dos Passos GR, Pichler A, Chung K, Hagens M, Ruggieri S, Auger C, Sastre-Garriga J, Enzinger C, Chard D, Barkhof F, Gasperini C, Rovira A, DeLuca G, et al. The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520943777. PMID 32757905 DOI: 10.1177/1352458520943777  0.321
2020 Alexander S, Peryer G, Gray E, Barkhof F, Chataway J. Wearable technologies to measure clinical outcomes in multiple sclerosis: A scoping review. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520946005. PMID 32749928 DOI: 10.1177/1352458520946005  0.306
2020 Goodkin O, Pemberton HG, Vos SB, Prados F, Das RK, Moggridge J, De Blasi B, Bartlett P, Williams E, Campion T, Haider L, Pearce K, Bargallό N, Sanchez E, Bisdas S, ... ... Barkhof F, et al. Clinical evaluation of automated quantitative MRI reports for assessment of hippocampal sclerosis. European Radiology. PMID 32749588 DOI: 10.1007/S00330-020-07075-2  0.347
2020 Heinen R, Groeneveld ON, Barkhof F, de Bresser J, Exalto LG, Kuijf HJ, Prins ND, Scheltens P, van der Flier WM, Biessels GJ. Small vessel disease lesion type and brain atrophy: The role of co-occurring amyloid. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12060. PMID 32695872 DOI: 10.1002/Dad2.12060  0.472
2020 Groot C, Yeo BTT, Vogel JW, Zhang X, Sun N, Mormino EC, Pijnenburg YAL, Miller BL, Rosen HJ, Joie R, Barkhof F, Scheltens P, van der Flier WM, Rabinovici GD, Ossenkoppele R. Latent atrophy factors related to phenotypical variants of posterior cortical atrophy. Neurology. PMID 32675078 DOI: 10.1212/Wnl.0000000000010362  0.44
2020 Jonkman LE, Steenwijk MD, Boesen N, Rozemuller AJM, Barkhof F, Geurts JJG, Douw L, van de Berg WDJ. Relationship between β-amyloid and structural network topology in decedents without dementia. Neurology. PMID 32661099 DOI: 10.1212/Wnl.0000000000009910  0.493
2020 de Sitter A, Verhoeven T, Burggraaff J, Liu Y, Simoes J, Ruggieri S, Palotai M, Brouwer I, Versteeg A, Wottschel V, Ropele S, Rocca MA, Gasperini C, Gallo A, Yiannakas MC, ... ... Barkhof F, et al. Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis: an evaluation of four automated methods against manual reference segmentations in a multi-center cohort. Journal of Neurology. PMID 32621103 DOI: 10.1007/S00415-020-10023-1  0.363
2020 Dicks E, van der Flier WM, Scheltens P, Barkhof F, Tijms BM. Single-subject gray matter networks predict future cortical atrophy in preclinical Alzheimer's disease. Neurobiology of Aging. 94: 71-80. PMID 32585492 DOI: 10.1016/J.Neurobiolaging.2020.05.008  0.5
2020 Visser M, Petr J, Müller DMJ, Eijgelaar RS, Hendriks EJ, Witte M, Barkhof F, van Herk M, Mutsaerts HJMM, Vrenken H, de Munck JC, De Witt Hamer PC. Accurate MR Image Registration to Anatomical Reference Space for Diffuse Glioma. Frontiers in Neuroscience. 14: 585. PMID 32581699 DOI: 10.3389/Fnins.2020.00585  0.301
2020 van Faals NL, Dekker I, Balk LJ, Moraal B, Barkhof F, Uitdehaag BMJ, Killestein J, Wattjes MP. Clinico-radiological dissociation of disease activity in MS patients: frequency and clinical relevance. Journal of Neurology. PMID 32564152 DOI: 10.1007/S00415-020-09991-1  0.339
2020 Mutsaerts HJMM, Petr J, Groot P, Vandemaele P, Ingala S, Robertson AD, Václavů L, Groote I, Kuijf H, Zelaya F, O'Daly O, Hilal S, Wink AM, Kant I, Caan MWA, ... ... Barkhof F, et al. ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies. Neuroimage. 117031. PMID 32526385 DOI: 10.1016/J.Neuroimage.2020.117031  0.636
2020 Ebenau JL, Timmers T, Wesselman LMP, Verberk IMW, Verfaillie SCJ, Slot RER, van Harten AC, Teunissen CE, Barkhof F, van den Bosch KA, van Leeuwenstijn M, Tomassen J, Braber AD, Visser PJ, Prins ND, et al. ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project. Neurology. PMID 32522798 DOI: 10.1212/Wnl.0000000000009724  0.453
2020 Quattrini G, Pievani M, Jovicich J, Aiello M, Bargalló N, Barkhof F, Bartres-Faz D, Beltramello A, Pizzini FB, Blin O, Bordet R, Caulo M, Constantinides M, Didic M, Drevelegas A, et al. Amygdalar nuclei and hippocampal subfields on MRI: test-retest reliability of automated volumetry across different MRI sites and vendors. Neuroimage. 116932. PMID 32416226 DOI: 10.1016/J.Neuroimage.2020.116932  0.308
2020 Cole JH, Raffel J, Friede T, Eshaghi A, Brownlee WJ, Chard D, De Stefano N, Enzinger C, Pirpamer L, Filippi M, Gasperini C, Rocca MA, Rovira A, Ruggieri S, Sastre-Garriga J, ... ... Barkhof F, et al. Longitudinal assessment of multiple sclerosis with the brain-age paradigm. Annals of Neurology. PMID 32285956 DOI: 10.1002/Ana.25746  0.313
2020 Lopes Alves I, Collij LE, Altomare D, Frisoni GB, Saint-Aubert L, Payoux P, Kivipelto M, Jessen F, Drzezga A, Leeuwis A, Wink AM, Visser PJ, van Berckel BNM, Scheltens P, Gray KR, ... ... Barkhof F, et al. Quantitative amyloid PET in Alzheimer's disease: the AMYPAD prognostic and natural history study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32281303 DOI: 10.1002/Alz.12069  0.684
2020 Pitkänen J, Koikkalainen J, Nieminen T, Marinkovic I, Curtze S, Sibolt G, Jokinen H, Rueckert D, Barkhof F, Schmidt R, Pantoni L, Scheltens P, Wahlund LO, Korvenoja A, Lötjönen J, et al. Evaluating severity of white matter lesions from computed tomography images with convolutional neural network. Neuroradiology. PMID 32281028 DOI: 10.1007/S00234-020-02410-2  0.438
2020 Sastre-Garriga J, Pareto D, Battaglini M, Rocca MA, Ciccarelli O, Enzinger C, Wuerfel J, Sormani MP, Barkhof F, Yousry TA, De Stefano N, Tintoré M, Filippi M, Gasperini C, Kappos L, et al. MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice. Nature Reviews. Neurology. 16: 171-182. PMID 32094485 DOI: 10.1038/S41582-020-0314-X  0.381
2020 van de Beek M, van Steenoven I, van der Zande JJ, Barkhof F, Teunissen CE, van der Flier WM, Lemstra AW. Prodromal Dementia with Lewy Bodies: Clinical Characterization and Predictors of Progression. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32048343 DOI: 10.1002/Mds.27997  0.353
2020 Geraldes R, Juryńczyk M, Dos Passos G, Prichler A, Chung K, Hagens M, Ruggieri S, Huerga E, Sastre-Garriga J, Enzinger C, Chard DT, Barkhof F, Gasperini C, Rovira A, DeLuca GC, et al. Distinct influence of different vascular risk factors on white matter brain lesions in multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 32034114 DOI: 10.1136/Jnnp-2019-322369  0.358
2020 Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, ... ... Barkhof F, et al. Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. Journal of Alzheimer's Disease : Jad. PMID 31985466 DOI: 10.3233/Jad-190434  0.47
2020 Rhodius-Meester HFM, van Maurik IS, Koikkalainen J, Tolonen A, Frederiksen KS, Hasselbalch SG, Soininen H, Herukka SK, Remes AM, Teunissen CE, Barkhof F, Pijnenburg YAL, Scheltens P, Lötjönen J, van der Flier WM. Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy. Plos One. 15: e0226784. PMID 31940390 DOI: 10.1371/Journal.Pone.0226784  0.444
2020 Bot JCJ, Mazzai L, Hagenbeek RE, Ingala S, van Oosten B, Sanchez-Aliaga E, Barkhof F. Brain miliary enhancement. Neuroradiology. PMID 31925469 DOI: 10.1007/S00234-019-02335-5  0.341
2020 Leijenaar JF, Groeneveld GJ, Klaassen ES, Leeuwis AE, Scheltens P, Weinstein HC, van Gerven JMA, Barkhof F, van der Flier WM, Prins ND. Methylphenidate and galantamine in patients with vascular cognitive impairment-the proof-of-principle study STREAM-VCI. Alzheimer's Research & Therapy. 12: 10. PMID 31910895 DOI: 10.1186/S13195-019-0567-Z  0.433
2019 Boon BDC, Pouwels PJW, Jonkman LE, Keijzer MJ, Preziosa P, van de Berg WDJ, Geurts JJG, Scheltens P, Barkhof F, Rozemuller AJM, Bouwman FH, Steenwijk MD. Can MRI be used as a proxy for ? A case study. Brain Communications. 1: fcz030. PMID 32954270 DOI: 10.1093/braincomms/fcz030  0.589
2019 Marizzoni M, Ferrari C, Babiloni C, Albani D, Barkhof F, Cavaliere L, Didic M, Forloni G, Fusco F, Galluzzi S, Hensch T, Jovicich J, Marra C, Molinuevo JL, Nobili F, et al. CSF cutoffs for MCI due to AD depend on APOEε4 carrier status. Neurobiology of Aging. PMID 32029236 DOI: 10.1016/J.Neurobiolaging.2019.12.019  0.344
2019 Reimand J, de Wilde A, Teunissen CE, Zwan M, Windhorst AD, Boellaard R, Barkhof F, van der Flier WM, Scheltens P, van Berckel BNM, Ossenkoppele R, Bouwman F. PET and CSF amyloid-β status are differently predicted by patient features: information from discordant cases. Alzheimer's Research & Therapy. 11: 100. PMID 31810489 DOI: 10.1186/S13195-019-0561-5  0.423
2019 Reimand J, Groot C, Teunissen CE, Windhorst AD, Boellaard R, Barkhof F, Nazarenko S, van der Flier WM, van Berckel BNM, Scheltens P, Ossenkoppele R, Bouwman F. Why Is Amyloid-β PET Requested After Performing Cerebrospinal Fluid Biomarkers? Journal of Alzheimer's Disease : Jad. PMID 31796674 DOI: 10.3233/Jad-190836  0.412
2019 Garbarino S, Lorenzi M, Oxtoby NP, Vinke EJ, Marinescu RV, Eshaghi A, Ikram MA, Niessen WJ, Ciccarelli O, Barkhof F, Schott JM, Vernooij MW, Alexander DC. Differences in topological progression profile among neurodegenerative diseases from imaging data. Elife. 8. PMID 31793876 DOI: 10.7554/Elife.49298  0.335
2019 Leijenaar JF, Groot C, Sudre CH, Bergeron D, Leeuwis AE, Cardoso MJ, Carrasco FP, Laforce R, Barkhof F, van der Flier WM, Scheltens P, Prins ND, Ossenkoppele R. Comorbid amyloid-β pathology affects clinical and imaging features in VCD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31786129 DOI: 10.1016/J.Jalz.2019.08.190  0.439
2019 Brugulat-Serrat A, Salvadó G, Operto G, Cacciaglia R, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Sánchez-Benavides G, Gramunt N, Minguillon C, Fauria K, Barkhof F, Molinuevo JL, Gispert JD, et al. White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants. Human Brain Mapping. PMID 31778002 DOI: 10.1002/Hbm.24877  0.375
2019 Canas LS, Sudre CH, De Vita E, Nihat A, Mok TH, Slattery CF, Paterson RW, Foulkes AJM, Hyare H, Cardoso MJ, Thornton J, Schott JM, Barkhof F, Collinge J, Ourselin S, et al. Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process. Neuroimage. Clinical. 24: 102051. PMID 31734530 DOI: 10.1016/J.Nicl.2019.102051  0.333
2019 Weeda MM, Brouwer I, de Vos ML, de Vries MS, Barkhof F, Pouwels PJW, Vrenken H. Comparing lesion segmentation methods in multiple sclerosis: Input from one manually delineated subject is sufficient for accurate lesion segmentation. Neuroimage. Clinical. 24: 102074. PMID 31734527 DOI: 10.1016/J.Nicl.2019.102074  0.333
2019 Wottschel V, Chard DT, Enzinger C, Filippi M, Frederiksen JL, Gasperini C, Giorgio A, Rocca MA, Rovira A, De Stefano N, Tintoré M, Alexander DC, Barkhof F, Ciccarelli O. SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of multiple sclerosis. Neuroimage. Clinical. 24: 102011. PMID 31734524 DOI: 10.1016/J.Nicl.2019.102011  0.357
2019 Heinen R, Steenwijk MD, Barkhof F, Biesbroek JM, van der Flier WM, Kuijf HJ, Prins ND, Vrenken H, Biessels GJ, de Bresser J. Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset. Scientific Reports. 9: 16742. PMID 31727919 DOI: 10.1038/S41598-019-52966-0  0.328
2019 Jokinen H, Koikkalainen J, Laakso HM, Melkas S, Nieminen T, Brander A, Korvenoja A, Rueckert D, Barkhof F, Scheltens P, Schmidt R, Fazekas F, Madureira S, Verdelho A, Wallin A, et al. Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline. Stroke. STROKEAHA119026170. PMID 31699021 DOI: 10.1161/Strokeaha.119.026170  0.517
2019 Chung KK, Altmann D, Barkhof F, Miszkiel K, Brex PA, O'Riordan J, Ebner M, Prados F, Cardoso MJ, Vercauteren T, Ourselin S, Thompson A, Ciccarelli O, Chard DT. A thirty year clinical and MRI observational study of multiple sclerosis and clinically isolated syndromes. Annals of Neurology. PMID 31693200 DOI: 10.1002/Ana.25637  0.309
2019 Scheltens NME, Briels CT, Yaqub M, Barkhof F, Boellaard R, van der Flier WM, Schwarte LA, Teunissen CE, Attali A, Broersen LM, van Berckel BNM, Scheltens P. Exploring effects of Souvenaid on cerebral glucose metabolism in Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 5: 492-500. PMID 31650005 DOI: 10.1016/J.Trci.2019.08.002  0.414
2019 Rocca MA, Valsasina P, Meani A, Gobbi C, Zecca C, Rovira À, Montalban X, Kearney H, Ciccarelli O, Matthews L, Palace J, Gallo A, Bisecco A, Gass A, Eisele P, ... ... Barkhof F, et al. Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS. Neurology. PMID 31611336 DOI: 10.1212/Wnl.0000000000008466  0.303
2019 Altomare D, de Wilde A, Ossenkoppele R, Pelkmans W, Bouwman F, Groot C, van Maurik I, Zwan M, Yaqub M, Barkhof F, van Berckel BN, Teunissen CE, Frisoni GB, Scheltens P, van der Flier WM. Applying the ATN scheme in a memory clinic population: The ABIDE project. Neurology. PMID 31597710 DOI: 10.1212/Wnl.0000000000008361  0.38
2019 de Wilde A, Ossenkoppele R, Pelkmans W, Bouwman F, Groot C, van Maurik I, Zwan M, Yaqub M, Barkhof F, Lammertsma AA, Biessels GJ, Scheltens P, van Berckel BN, van der Flier WM. Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31594684 DOI: 10.1016/J.Jalz.2019.07.003  0.413
2019 Beltrán E, Gerdes LA, Hansen J, Flierl-Hecht A, Krebs S, Blum H, Ertl-Wagner B, Barkhof F, Kümpfel T, Hohlfeld R, Dornmair K. Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. The Journal of Clinical Investigation. PMID 31566584 DOI: 10.1172/Jci128475  0.324
2019 Verburg N, Koopman T, Yaqub MM, Hoekstra OS, Lammertsma AA, Barkhof F, Pouwels PJW, Reijneveld JC, Heimans JJ, Rozemuller AJM, Bruynzeel AME, Lagerwaard F, Vandertop WP, Boellaard R, Wesseling P, et al. Improved detection of diffuse glioma infiltration with imaging combinations: a diagnostic accuracy study. Neuro-Oncology. PMID 31550353 DOI: 10.1093/Neuonc/Noz180  0.565
2019 van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Frolich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Frisoni GB, et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. PMID 31526625 DOI: 10.1016/S1474-4422(19)30283-2  0.452
2019 Weaver NA, Doeven T, Barkhof F, Biesbroek JM, Groeneveld ON, Kuijf HJ, Prins ND, Scheltens P, Teunissen CE, van der Flier WM, Biessels GJ. Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions. Neurobiology of Aging. PMID 31500909 DOI: 10.1016/J.Neurobiolaging.2019.08.001  0.498
2019 Elliott C, Belachew S, Wolinsky JS, Hauser SL, Kappos L, Barkhof F, Bernasconi C, Fecker J, Model F, Wei W, Arnold DL. Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis. Brain : a Journal of Neurology. 142: 2787-2799. PMID 31497864 DOI: 10.1093/Brain/Awz212  0.348
2019 Shi L, Westwood S, Baird AL, Winchester L, Dobricic V, Kilpert F, Hong S, Franke A, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Buckley NJ, Kate MT, ... ... Barkhof F, et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31495601 DOI: 10.1016/J.Jalz.2019.06.4951  0.421
2019 Eijlers AJC, Dekker I, Steenwijk MD, Meijer KA, Hulst HE, Pouwels PJW, Uitdehaag BMJ, Barkhof F, Vrenken H, Schoonheim MM, Geurts JJG. Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis. Neurology. PMID 31484713 DOI: 10.1212/Wnl.0000000000008198  0.576
2019 Barkhof F, Kappos L, Wolinsky JS, Li DKB, Bar-Or A, Hartung HP, Belachew S, Han J, Julian L, Sauter A, Napieralski J, Koendgen H, Hauser SL. Onset of clinical and MRI efficacy of ocrelizumab in relapsing multiple sclerosis. Neurology. PMID 31484710 DOI: 10.1212/Wnl.0000000000008189  0.354
2019 Weeda MM, Middelkoop SM, Steenwijk MD, Daams M, Amiri H, Brouwer I, Killestein J, Uitdehaag BMJ, Dekker I, Lukas C, Bellenberg B, Barkhof F, Pouwels PJW, Vrenken H. Validation of mean upper cervical cord area (MUCCA) measurement techniques in multiple sclerosis (MS): High reproducibility and robustness to lesions, but large software and scanner effects. Neuroimage. Clinical. 24: 101962. PMID 31416017 DOI: 10.1016/J.Nicl.2019.101962  0.338
2019 Legdeur N, Tijms BM, Konijnenberg E, den Braber A, Ten Kate M, Sudre CH, Tomassen J, Badissi M, Yaqub M, Barkhof F, van Berckel BN, Boomsma DI, Scheltens P, Holstege H, Maier AB, et al. Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 31411322 DOI: 10.1093/Gerona/Glz180  0.461
2019 Habets EJJ, Hendriks EJ, Taphoorn MJB, Douw L, Zwinderman AH, Vandertop WP, Barkhof F, De Witt Hamer PC, Klein M. Association between tumor location and neurocognitive functioning using tumor localization maps. Journal of Neuro-Oncology. PMID 31410731 DOI: 10.1007/S11060-019-03259-Z  0.305
2019 Cotta Ramusino M, Altomare D, Bacchin R, Ingala S, Bnà C, Bonetti M, Costa A, Barkhof F, Nicolosi V, Festari C, Frisoni GB, Boccardi M. Medial temporal lobe atrophy and posterior atrophy scales normative values. Neuroimage. Clinical. 24: 101936. PMID 31382240 DOI: 10.1016/J.Nicl.2019.101936  0.313
2019 Dekker I, Sombekke MH, Balk LJ, Moraal B, Geurts JJ, Barkhof F, Uitdehaag BM, Killestein J, Wattjes MP. Infratentorial and spinal cord lesions: Cumulative predictors of long-term disability? Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519864933. PMID 31373535 DOI: 10.1177/1352458519864933  0.51
2019 Goodkin O, Pemberton H, Vos SB, Prados F, Sudre CH, Moggridge J, Cardoso MJ, Ourselin S, Bisdas S, White M, Yousry T, Thornton J, Barkhof F. The quantitative neuroradiology initiative framework: application to dementia. The British Journal of Radiology. 20190365. PMID 31368776 DOI: 10.1259/Bjr.20190365  0.332
2019 Archetti D, Ingala S, Venkatraghavan V, Wottschel V, Young AL, Bellio M, Bron EE, Klein S, Barkhof F, Alexander DC, Oxtoby NP, Frisoni GB, Redolfi A. Multi-study validation of data-driven disease progression models to characterize evolution of biomarkers in Alzheimer's disease. Neuroimage. Clinical. 24: 101954. PMID 31362149 DOI: 10.1016/J.Nicl.2019.101954  0.37
2019 Brownlee WJ, Altmann DR, Prados F, Miszkiel KA, Eshaghi A, Gandini Wheeler-Kingshott CAM, Barkhof F, Ciccarelli O. Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis. Brain : a Journal of Neurology. 142: 2276-2287. PMID 31342055 DOI: 10.1093/Brain/Awz156  0.387
2019 Collorone S, Prados F, Hagens MH, Tur C, Kanber B, Sudre CH, Lukas C, Gasperini C, Oreja-Guevara C, Andelova M, Ciccarelli O, Wattjes MP, Ourselin S, Altmann DR, Tijms BM, ... Barkhof F, et al. Single-subject structural cortical networks in clinically isolated syndrome. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519865739. PMID 31339446 DOI: 10.1177/1352458519865739  0.351
2019 Brugulat-Serrat A, Salvadó G, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Sánchez-Benavides G, Gramunt N, Fauria K, Cardoso MJ, Barkhof F, Molinuevo JL, Gispert JD. Patterns of white matter hyperintensities associated with cognition in middle-aged cognitively healthy individuals. Brain Imaging and Behavior. PMID 31278650 DOI: 10.1007/S11682-019-00151-2  0.35
2019 Timmers T, Ossenkoppele R, Wolters EE, Verfaillie SCJ, Visser D, Golla SSV, Barkhof F, Scheltens P, Boellaard R, van der Flier WM, van Berckel BNM. Associations between quantitative [F]flortaucipir tau PET and atrophy across the Alzheimer's disease spectrum. Alzheimer's Research & Therapy. 11: 60. PMID 31272512 DOI: 10.1186/S13195-019-0510-3  0.433
2019 Altomare D, Ferrari C, Caroli A, Galluzzi S, Prestia A, van der Flier WM, Ossenkoppele R, Van Berckel B, Barkhof F, Teunissen CE, Wall A, Carter SF, Schöll M, Choo ILH, Grimmer T, et al. Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset. Journal of Neurology. PMID 31267207 DOI: 10.1007/S00415-019-09441-7  0.464
2019 van Loenhoud AC, van der Flier WM, Wink AM, Dicks E, Groot C, Twisk J, Barkhof F, Scheltens P, Ossenkoppele R. Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship. Neurology. PMID 31266904 DOI: 10.1212/Wnl.0000000000007821  0.69
2019 Verburg N, Koopman T, Yaqub M, Hoekstra OS, Lammertsma AA, Schwarte LA, Barkhof F, Pouwels PJW, Heimans JJ, Reijneveld JC, Rozemuller AJM, Vandertop WP, Wesseling P, Boellaard R, de Witt Hamer PC. Direct comparison of [C] choline and [F] FET PET to detect glioma infiltration: a diagnostic accuracy study in eight patients. Ejnmmi Research. 9: 57. PMID 31254208 DOI: 10.1186/S13550-019-0523-8  0.505
2019 Haan JD, van de Kreeke JA, Konijnenberg E, Kate MT, Braber AD, Barkhof F, van Berckel BN, Teunissen CE, Scheltens P, Visser PJ, Verbraak FD, Bouwman FH. Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 463-471. PMID 31249859 DOI: 10.1016/J.Dadm.2019.05.002  0.435
2019 Bartel F, Visser M, de Ruiter M, Belderbos J, Barkhof F, Vrenken H, de Munck JC, van Herk M. Non-linear registration improves statistical power to detect hippocampal atrophy in aging and dementia. Neuroimage. Clinical. 23: 101902. PMID 31233953 DOI: 10.1016/J.Nicl.2019.101902  0.343
2019 Filippi M, Preziosa P, Banwell BL, Barkhof F, Ciccarelli O, De Stefano N, Geurts JJG, Paul F, Reich DS, Toosy AT, Traboulsee A, Wattjes MP, Yousry TA, Gass A, Lubetzki C, et al. Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines. Brain : a Journal of Neurology. PMID 31209474 DOI: 10.1093/Brain/Awz144  0.578
2019 Battaglini M, Gentile G, Luchetti L, Giorgio A, Vrenken H, Barkhof F, Cover KS, Bakshi R, Chu R, Sormani MP, Enzinger C, Ropele S, Ciccarelli O, Wheeler-Kingshott C, Yiannakas M, et al. Lifespan normative data on rates of brain volume changes. Neurobiology of Aging. 81: 30-37. PMID 31207467 DOI: 10.1016/J.Neurobiolaging.2019.05.010  0.327
2019 Haan JD, van de Kreeke JA, van Berckel BN, Barkhof F, Teunissen CE, Scheltens P, Verbraak FD, Bouwman FH. Is retinal vasculature a biomarker in amyloid proven Alzheimer's disease? Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 383-391. PMID 31193094 DOI: 10.1016/J.Dadm.2019.03.006  0.437
2019 Dekker I, Leurs CE, Hagens MHJ, van Kempen ZLE, Kleerekooper I, Lissenberg-Witte BI, Barkhof F, Uitdehaag BMJ, Balk LJ, Wattjes MP, Killestein J. Long-term disease activity and disability progression in relapsing-remitting multiple sclerosis patients on natalizumab. Multiple Sclerosis and Related Disorders. 33: 82-87. PMID 31174043 DOI: 10.1016/J.Msard.2019.05.017  0.357
2019 Mancini M, Vos SB, Vakharia VN, O'Keeffe AG, Trimmel K, Barkhof F, Dorfer C, Soman S, Winston GP, Wu C, Duncan JS, Sparks R, Ourselin S. Automated fiber tract reconstruction for surgery planning: Extensive validation in language-related white matter tracts. Neuroimage. Clinical. 23: 101883. PMID 31163386 DOI: 10.1016/J.Nicl.2019.101883  0.306
2019 Pelkmans W, Dicks E, Barkhof F, Vrenken H, Scheltens P, van der Flier WM, Tijms BM. Gray matter T1-w/T2-w ratios are higher in Alzheimer's disease. Human Brain Mapping. PMID 31157938 DOI: 10.1002/Hbm.24638  0.463
2019 Frisoni GB, Alves IL, Barkhof F. IDEAS becoming reality on the roadmap for biomarker validation in Alzheimer's disease. The Lancet. Neurology. 18: 519-520. PMID 31122488 DOI: 10.1016/S1474-4422(19)30166-8  0.309
2019 Kim M, Snowden S, Suvitaival T, Ali A, Merkler DJ, Ahmad T, Westwood S, Baird A, Proitsi P, Nevado-Holgado A, Hye A, Bos I, Vos S, Vandenberghe R, Teunissen C, ... ... Barkhof F, et al. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31078433 DOI: 10.1016/J.Jalz.2019.03.004  0.467
2019 Tur C, Grussu F, Prados F, Charalambous T, Collorone S, Kanber B, Cawley N, Altmann DR, Ourselin S, Barkhof F, Clayden JD, Toosy AT, Wheeler-Kingshott CAG, Ciccarelli O. A multi-shell multi-tissue diffusion study of brain connectivity in early multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519845105. PMID 31074686 DOI: 10.1177/1352458519845105  0.336
2019 Eshaghi A, Kievit RA, Prados F, Sudre CH, Nicholas J, Cardoso MJ, Chan D, Nicholas R, Ourselin S, Greenwood J, Thompson AJ, Alexander DC, Barkhof F, Chataway J, Ciccarelli O. Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31072935 DOI: 10.1073/Pnas.1818978116  0.33
2019 Morgan AR, Touchard S, Leckey C, O'Hagan C, Nevado-Holgado AJ, Barkhof F, Bertram L, Blin O, Bos I, Dobricic V, Engelborghs S, Frisoni G, Frölich L, Gabel S, et al. Inflammatory biomarkers in Alzheimer's disease plasma. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31047856 DOI: 10.1016/J.Jalz.2019.03.007  0.421
2019 Leeuwis AE, Weaver NA, Biesbroek JM, Exalto LG, Kuijf HJ, Hooghiemstra AM, Prins ND, Scheltens P, Barkhof F, van der Flier WM, Biessels GJ. Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study Journal of Psychiatry & Neuroscience : Jpn. 44: 1-10. PMID 31021068 DOI: 10.1503/Jpn.180136  0.386
2019 van Maurik IS, Slot RER, Verfaillie SCJ, Zwan MD, Bouwman FH, Prins ND, Teunissen CE, Scheltens P, Barkhof F, Wattjes MP, Molinuevo JL, Rami L, Wolfsgruber S, Peters O, Jessen F, et al. Personalized risk for clinical progression in cognitively normal subjects-the ABIDE project. Alzheimer's Research & Therapy. 11: 33. PMID 30987684 DOI: 10.1186/S13195-019-0487-Y  0.49
2019 Dicks E, Vermunt L, van der Flier WM, Visser PJ, Barkhof F, Scheltens P, Tijms BM. Modeling grey matter atrophy as a function of time, aging or cognitive decline show different anatomical patterns in Alzheimer's disease. Neuroimage. Clinical. 22: 101786. PMID 30921610 DOI: 10.1016/J.Nicl.2019.101786  0.479
2019 Boomsma JMF, Exalto LG, Barkhof F, Berg EVD, Bresser J, Heinen R, Leeuwis AE, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ. How Do Different Forms of Vascular Brain Injury Relate to Cognition in a Memory Clinic Population: The TRACE-VCI Study. Journal of Alzheimer's Disease : Jad. PMID 30909212 DOI: 10.3233/Jad-180696  0.458
2019 Kuijf HJ, Biesbroek JM, de Bresser J, Heinen R, Andermatt S, Bento M, Berseth M, Belyaev M, Cardoso MJ, Casamitjana A, Collins DL, Dadar M, Georgiou A, Ghafoorian M, Jin D, ... ... Barkhof F, et al. Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities; Results of the WMH Segmentation Challenge. Ieee Transactions On Medical Imaging. PMID 30908194 DOI: 10.1109/Tmi.2019.2905770  0.318
2019 d'Ambrosio A, Valsasina P, Gallo A, De Stefano N, Pareto D, Barkhof F, Ciccarelli O, Enzinger C, Tedeschi G, Stromillo ML, Arévalo MJ, Hulst HE, Muhlert N, Koini M, Filippi M, et al. Reduced dynamics of functional connectivity and cognitive impairment in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519837707. PMID 30887862 DOI: 10.1177/1352458519837707  0.37
2019 Bos I, Vos S, Verhey F, Scheltens P, Teunissen C, Engelborghs S, Sleegers K, Frisoni G, Blin O, Richardson JC, Bordet R, Tsolaki M, Popp J, Peyratout G, Martinez-Lage P, ... ... Barkhof F, et al. Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30853464 DOI: 10.1016/J.Jalz.2019.01.004  0.455
2019 Vernooij MW, Pizzini FB, Schmidt R, Smits M, Yousry TA, Bargallo N, Frisoni GB, Haller S, Barkhof F. Dementia imaging in clinical practice: a European-wide survey of 193 centres and conclusions by the ESNR working group. Neuroradiology. PMID 30852630 DOI: 10.1007/S00234-019-02188-Y  0.308
2019 Ferro DA, van den Brink H, Exalto LG, Boomsma JMF, Barkhof F, Prins ND, van der Flier WM, Biessels GJ. Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment. Neurology. PMID 30850444 DOI: 10.1212/Wnl.0000000000007250  0.324
2019 Visser M, Müller DMJ, van Duijn RJM, Smits M, Verburg N, Hendriks EJ, Nabuurs RJA, Bot JCJ, Eijgelaar RS, Witte M, van Herk MB, Barkhof F, de Witt Hamer PC, de Munck JC. Inter-rater agreement in glioma segmentations on longitudinal MRI. Neuroimage. Clinical. 22: 101727. PMID 30825711 DOI: 10.1016/J.Nicl.2019.101727  0.311
2019 Koikkalainen JR, Rhodius-Meester HFM, Frederiksen KS, Bruun M, Hasselbalch SG, Baroni M, Mecocci P, Vanninen R, Remes A, Soininen H, van Gils M, van der Flier WM, Scheltens P, Barkhof F, Erkinjuntti T, et al. Automatically computed rating scales from MRI for patients with cognitive disorders. European Radiology. PMID 30796570 DOI: 10.1007/S00330-019-06067-1  0.422
2019 Groeneveld ON, Moneti C, Heinen R, de Bresser J, Kuijf HJ, Exalto LG, Boomsma JMF, Kappelle LJ, Barkhof F, Prins ND, Scheltens P, van der Flier WM, Biessels GJ. The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus. Journal of Alzheimer's Disease : Jad. PMID 30775988 DOI: 10.3233/Jad-180914  0.453
2019 Bruun M, Koikkalainen J, Rhodius-Meester HFM, Baroni M, Gjerum L, van Gils M, Soininen H, Remes AM, Hartikainen P, Waldemar G, Mecocci P, Barkhof F, Pijnenburg Y, van der Flier WM, Hasselbalch SG, et al. Detecting frontotemporal dementia syndromes using MRI biomarkers. Neuroimage. Clinical. 22: 101711. PMID 30743135 DOI: 10.1016/J.Nicl.2019.101711  0.367
2019 Jonkman LE, Graaf YG, Bulk M, Kaaij E, Pouwels PJW, Barkhof F, Rozemuller AJM, van der Weerd L, Geurts JJG, van de Berg WDJ. Normal Aging Brain Collection Amsterdam (NABCA): A comprehensive collection of postmortem high-field imaging, neuropathological and morphometric datasets of non-neurological controls. Neuroimage. Clinical. 22: 101698. PMID 30711684 DOI: 10.1016/J.Nicl.2019.101698  0.53
2019 Salvadó G, Brugulat-Serrat A, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Fauria K, Cardoso MJ, Barkhof F, Molinuevo JL, Gispert JD. Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort. Alzheimer's Research & Therapy. 11: 12. PMID 30678723 DOI: 10.1186/S13195-018-0460-1  0.329
2019 Amiri H, Brouwer I, Kuijer JPA, de Munck JC, Barkhof F, Vrenken H. Novel imaging phantom for accurate and robust measurement of brain atrophy rates using clinical MRI. Neuroimage. Clinical. 21: 101667. PMID 30665101 DOI: 10.1016/J.Nicl.2019.101667  0.378
2019 Emanuel AL, van Duinkerken E, Wattjes MP, Klein M, Barkhof F, Snoek FJ, Diamant M, Eringa EC, IJzerman RG, Serné EH. The presence of cerebral white matter lesions and lower skin microvascular perfusion predict lower cognitive performance in type 1 diabetes patients with retinopathy but not in healthy controls - a longitudinal study. Microcirculation (New York, N.Y. : 1994). e12530. PMID 30659710 DOI: 10.1111/Micc.12530  0.324
2019 Dekker I, Eijlers AJC, Popescu V, Balk LJ, Vrenken H, Wattjes MP, Uitdehaag BMJ, Killestein J, Geurts JJG, Barkhof F, Schoonheim MM. Predicting clinical progression in multiple sclerosis after 6 and 12 years. European Journal of Neurology. PMID 30629788 DOI: 10.1111/Ene.13904  0.37
2019 Garbarino S, Lorenzi M, Oxtoby NP, Vinke EJ, Marinescu RV, Eshaghi A, Ikram MA, Niessen WJ, Ciccarelli O, Barkhof F, Schott JM, Vernooij MW, Alexander DC. Author response: Differences in topological progression profile among neurodegenerative diseases from imaging data Elife. DOI: 10.7554/Elife.49298.Sa2  0.311
2019 Leeuwis AE, Hooghiemstra AM, Bron EE, Brunner-La Rocca HP, Kappelle LJ, Van Oostenbrugge RJ, Greving JP, Niessen WJ, Van Buchem MA, Van Osch MJP, Van Rossum AC, Prins ND, Biessels GJ, Barkhof F, Van Der Flier WM. P3714Cerebral blood flow and cognitive functioning in the heart-brain axis European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz745.0568  0.34
2019 Hönig MC, Bischof GN, Alves IL, Ahlswede M, Sakagiannis P, Jessen F, Schmidt ME, Barkhof F, Eimeren Tv, Drzezga A. P1‐350: Hippocampal Intrinsic Connectivity Supports Cognitive Reserve In Amyloid‐Positive Cognitively Normal Subjects And Alzheimer'S Disease Patients Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.905  0.359
2019 Lötjönen J, Koikkalainen J, Meester HFMR, Baroni M, Mecocci P, Remes A, Soininen H, Erkinjuntti T, Teunissen CE, Scheltens P, Barkhof F, Flier WMvd, Law I, Hasselbalch SG, Frederiksen KS. P1‐347: Detecting Alzheimer'S Disease At Different Levels Of White‐Matter Hyperintensities Using Mri Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.902  0.462
2019 Singleton EH, Pijnenburg YAL, Sudre CH, Kochova E, Groot C, Papma JM, Swieten JCv, Barkhof F, Scheltens P, Rabinovici GD, Ossenkoppele R. Ic-P-097: Differentiating The Behavioural Variant Of Alzheimer'S Disease From Behavioural Variant Frontotemporal Dementia And Typical Alzheimer'S Disease: The Value Of Neuroimaging Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4940  0.444
2019 Bos I, Vos SJB, Kate Mt, Jansen WJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, ... ... Barkhof F, et al. Associations Between Cerebrospinal Fluid Neurodegenerative Markers, Neurofilament-Light And Total Tau And Cerebrovascular Imaging Markers Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4860  0.402
2019 Loenhoud ACv, Groot C, Barkhof F, Scheltens P, Flier WMvd, Ossenkoppele R. Ic-P-100: A Longitudinal Study Of The Effects Of Education And Intracranial Volume On Cognitive Changes And Mortality Rates In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4766  0.444
2019 Leijenaar JF, Groot C, Sudre CH, Bergeron D, Leeuwis AE, Cardoso J, Carrasco FP, Laforce R, Barkhof F, Flier WMvd, Scheltens P, Prins ND, Ossenkoppele R. COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4647  0.431
2019 Salvadó G, Ferreira D, Cacciaglia R, Operto G, Falcon C, Groot C, Flier WMvd, Barkhof F, Scheltens P, Ossenkoppele R, Stomrud E, Westen Dv, Hansson O, Molinuevo JL, Wahlund L, et al. O3-02-06: COGNITIVELY NORMAL APOE-ε2 HOMOZYGOTES DISPLAY GREATER HIPPOCAMPI: AN UNBIASED VOXEL-BASED ANALYSIS Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4635  0.421
2019 Meester HFR, Maurik ISV, Koikkalainen J, Barkhof F, Teunissen CE, Frederiksen KS, Scheltens P, Meccocci P, Baroni M, Remes A, Soininen H, Hasselbalch SG, Flier WMvd, Lötjönen J. O2-02-03: Stepwise Patient Selection For Amyloid Measurements Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4459  0.378
2019 Ebenau J, Timmers T, Wesselman LMP, Verberk IMW, Verfaillie SCJ, Slot RER, Teunissen CE, Barkhof F, Bosch Kvd, Leeuwenstijn Mv, Prins ND, Sikkes SAM, Scheltens P, Berckel BNMV, Flier WMvd. Atn Biomarker Model As A Determinant Of Cognitive Decline And Incident Clinical Progression In Subjective Cognitive Decline: The Science Project Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4383  0.434
2019 Dicks E, van der Flier WM, Barkhof F, Scheltens P, Tijms BM. IC-02-01: GREY MATTER CONNECTIVITY TRAJECTORIES ACROSS THE ALZHEIMER'S DISEASE CONTINUUM AND ASSOCIATIONS WITH COGNITIVE DECLINE Alzheimer's & Dementia. 15: P1-P1. DOI: 10.1016/J.Jalz.2019.06.4145  0.469
2019 Aksman LM, Alexander DC, Barkhof F, Altmann A. P4-320: AMYLOID-BETA ACCUMULATION AFFECTS IN VIVO STAGING OF TAU DEPOSITION IN COGNITIVELY IMPAIRED INDIVIDUALS Alzheimer's & Dementia. 15: P1416-P1417. DOI: 10.1016/J.Jalz.2019.06.3990  0.305
2019 Alves IL, Doull L, Gunn F, Farrar G, Barkhof F, Ford L, Ritchie CW. P4-307: The Added Value Of Quantitative Amyloid Pet In Determining Alzheimer'S Disease (Ad) Dementia Risk: The Amypad Prognostic And Natural History Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3977  0.322
2019 Groot C, Risacher SL, Chen JA, Saykin AJ, MacDonald C, Mez J, Trittschuh EH, Mukherjee S, Gibbons LE, Choi S, Sanders RE, Dicks E, Barkhof F, Scheltens P, van der Flier WM, et al. P3-422: FDG-PET REVEALS DISTINCT HYPOMETABOLIC TRAJECTORIES IN COGNITIVELY DEFINED SUBGROUPS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1119-P1120. DOI: 10.1016/J.Jalz.2019.06.3456  0.453
2019 Altomare D, Barkhof F, Berkhof J, Boccardi M, Canzoneri E, Collij L, Drzezga A, Farrar G, Garibotto V, Gismondi R, Gispert JD, Jessen F, Kivipelto M, Alves IL, Molinuevo JL, et al. P3-373: Amypad-Dpms Preliminary Results: Participants’ Baseline Features Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3406  0.348
2019 Brugulat-Serrat A, Salvadó G, Operto G, Cacciaglia R, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Sánchez-Benavides G, Gramunt N, Minguillon C, Fauria K, Barkhof F, Molinuevo JL, Gispert JD, et al. P3-323: White Matter Hyperintensities Mediate The Relationship Between Gray Matter Volume And Executive Function In Cognitively Unimpaired Middle-Aged Individuals Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3355  0.325
2019 Legdeur N, Badissi M, Yaqub MM, Beker N, Sudre CH, Kate Mt, Gordon MF, Novak GP, Barkhof F, Berckel BNMV, Holstege H, Muller M, Scheltens P, Maier AB, Visser PJ. P2-345: What Determines Cognitive Functioning In The Oldest-Old? The Emif-Ad 90+ Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2752  0.45
2019 Briels CT, Scheltens NME, Yaqub MM, Barkhof F, Boellaard R, Flier WMvd, Schwarte LA, Teunissen CE, Broersen LM, Berckel BNMV, Scheltens P. P2-016: Exploring The Effect Of Souvenaid On Cerebral Glucose Metabolism In Early Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1238  0.411
2019 Salvadó G, Collij L, Niñerola-Baizán A, Perissinotti A, Flier WMvd, Visser PJ, Scheltens P, Zetterberg H, Blennow K, Barkhof F, Molinuevo JL, Alves IL, Gispert JD, Study A, Adni. Ic-P-015: Voxel-Based Amyloid Pet Staging For The Whole Alzheimer'S Disease Continuum Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1026  0.42
2018 Rhodius-Meester HFM, Liedes H, Koikkalainen J, Wolfsgruber S, Coll-Padros N, Kornhuber J, Peters O, Jessen F, Kleineidam L, Molinuevo JL, Rami L, Teunissen CE, Barkhof F, Sikkes SAM, Wesselman LMP, et al. Computer-assisted prediction of clinical progression in the earliest stages of AD. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 726-736. PMID 30619929 DOI: 10.1016/J.Dadm.2018.09.001  0.454
2018 Gasperini C, Prosperini L, Tintoré M, Sormani MP, Filippi M, Rio J, Palace J, Rocca MA, Ciccarelli O, Barkhof F, Sastre-Garriga J, Vrenken H, Frederiksen JL, Yousry TA, Enzinger C, et al. Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge. Neurology. PMID 30587516 DOI: 10.1212/Wnl.0000000000006810  0.355
2018 Elliott C, Wolinsky JS, Hauser SL, Kappos L, Barkhof F, Bernasconi C, Wei W, Belachew S, Arnold DL. Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518814117. PMID 30566027 DOI: 10.1177/1352458518814117  0.359
2018 Jutten RJ, Dicks E, Vermaat L, Barkhof F, Scheltens P, Tijms BM, Sikkes SAM. Impairment in complex activities of daily living is related to neurodegeneration in Alzheimer's disease-specific regions. Neurobiology of Aging. 75: 109-116. PMID 30557769 DOI: 10.1016/J.Neurobiolaging.2018.11.018  0.502
2018 Legdeur N, Badissi M, Carter SF, de Crom S, van de Kreeke A, Vreeswijk R, Trappenburg MC, Oudega ML, Koek HL, van Campen JP, Keijsers CJPW, Amadi C, Hinz R, Gordon MF, Novak G, ... ... Barkhof F, et al. Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+ study. Bmc Geriatrics. 18: 289. PMID 30477432 DOI: 10.1186/S12877-018-0984-Z  0.455
2018 Ten Kate M, Ingala S, Schwarz AJ, Fox NC, Chételat G, van Berckel BNM, Ewers M, Foley C, Gispert JD, Hill D, Irizarry MC, Lammertsma AA, Molinuevo JL, Ritchie C, Scheltens P, ... ... Barkhof F, et al. Secondary prevention of Alzheimer's dementia: neuroimaging contributions. Alzheimer's Research & Therapy. 10: 112. PMID 30376881 DOI: 10.1186/S13195-018-0438-Z  0.475
2018 Ten Kate M, Dicks E, Visser PJ, van der Flier WM, Teunissen CE, Barkhof F, Scheltens P, Tijms BM. Atrophy subtypes in prodromal Alzheimer's disease are associated with cognitive decline. Brain : a Journal of Neurology. PMID 30351346 DOI: 10.1093/Brain/Awy264  0.502
2018 Groot C, Sudre CH, Barkhof F, Teunissen CE, van Berckel BNM, Seo SW, Ourselin S, Scheltens P, Cardoso MJ, van der Flier WM, Ossenkoppele R. Clinical phenotype, atrophy, and small vessel disease in ε2 carriers with Alzheimer disease. Neurology. PMID 30341156 DOI: 10.1212/Wnl.0000000000006503  0.475
2018 Frisoni GB, Barkhof F, Altomare D, Berkhof J, Boccardi M, Canzoneri E, Collij L, Drzezga A, Farrar G, Garibotto V, Gismondi R, Gispert JD, Jessen F, Kivipelto M, Alves IL, et al. AMYPAD Diagnostic and Patient Management Study: Rationale and design. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30339801 DOI: 10.1016/J.Jalz.2018.09.003  0.442
2018 Hu X, Teunissen C, Spottke A, Heneka MT, Düzel E, Peters O, Li S, Priller J, Bürger K, Teipel S, Laske C, Verfaillie S, Barkhof F, Coll-Padrós N, Rami L, et al. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321506 DOI: 10.1016/J.Jalz.2018.09.002  0.406
2018 Bruun M, Rhodius-Meester HFM, Koikkalainen J, Baroni M, Gjerum L, Lemstra AW, Barkhof F, Remes AM, Urhemaa T, Tolonen A, Rueckert D, van Gils M, Frederiksen KS, Waldemar G, Scheltens P, et al. Evaluating combinations of diagnostic tests to discriminate different dementia types. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 509-518. PMID 30320203 DOI: 10.1016/J.Dadm.2018.07.003  0.398
2018 Collij L, Konijnenberg E, Reimand J, Ten Kate M, Den Braber A, Lopes Alves I, Zwan M, Yaqub M, Van Assema D, Wink AM, Lammertsma A, Scheltens P, Visser PJ, Barkhof F, Van Berckel B. Assessing Amyloid Pathology in Cognitively Normal Subjects using [F]Flutemetamol PET: Comparing Visual Reads and Quantitative Methods. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30315145 DOI: 10.2967/Jnumed.118.211532  0.678
2018 Leeuwis AE, Smith LA, Melbourne A, Hughes AD, Richards M, Prins ND, Sokolska M, Atkinson D, Tillin T, Jäger HR, Chaturvedi N, van der Flier WM, Barkhof F. Cerebral Blood Flow and Cognitive Functioning in a Community-Based, Multi-Ethnic Cohort: The SABRE Study. Frontiers in Aging Neuroscience. 10: 279. PMID 30279656 DOI: 10.3389/Fnagi.2018.00279  0.336
2018 Rocca MA, Barkhof F, De Luca J, Frisén J, Geurts JJG, Hulst HE, Sastre-Garriga J, Filippi M. The hippocampus in multiple sclerosis. The Lancet. Neurology. 17: 918-926. PMID 30264730 DOI: 10.1016/S1474-4422(18)30309-0  0.553
2018 Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R, Gabel S, Schaeverbeke J, Scheltens P, Blin O, Richardson JC, Bordet R, Wallin A, Eckerstrom C, Molinuevo JL, ... ... Barkhof F, et al. MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study. Alzheimer's Research & Therapy. 10: 100. PMID 30261928 DOI: 10.1186/S13195-018-0428-1  0.479
2018 Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, et al. Correction to: A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease. Alzheimer's Research & Therapy. 10: 99. PMID 30261916 DOI: 10.1186/S13195-018-0409-4  0.375
2018 Eijlers AJC, van Geest Q, Dekker I, Steenwijk MD, Meijer KA, Hulst HE, Barkhof F, Uitdehaag BMJ, Schoonheim MM, Geurts JJG. Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study. Brain : a Journal of Neurology. 141: 2605-2618. PMID 30169585 DOI: 10.1093/Brain/Awy202  0.611
2018 Connick P, De Angelis F, Parker RA, Plantone D, Doshi A, John N, Stutters J, MacManus D, Prados Carrasco F, Barkhof F, Ourselin S, Braisher M, Ross M, Cranswick G, Pavitt SH, et al. Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (MS-SMART): a multiarm phase IIb randomised, double-blind, placebo-controlled clinical trial comparing the efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis. Bmj Open. 8: e021944. PMID 30166303 DOI: 10.1136/Bmjopen-2018-021944  0.315
2018 Bendfeldt K, Taschler B, Gaetano L, Madoerin P, Kuster P, Mueller-Lenke N, Amann M, Vrenken H, Wottschel V, Barkhof F, Borgwardt S, Klöppel S, Wicklein EM, Kappos L, Edan G, et al. MRI-based prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis using SVM and lesion geometry. Brain Imaging and Behavior. PMID 30155789 DOI: 10.1007/S11682-018-9942-9  0.39
2018 Wink AM, Tijms BM, Ten Kate M, Raspor E, de Munck JC, Altena E, Ecay-Torres M, Clerigue M, Estanga A, Garcia-Sebastian M, Izagirre A, Martinez-Lage Alvarez P, Villanua J, Barkhof F, Sanz-Arigita E. Functional brain network centrality is related to APOE genotype in cognitively normal elderly. Brain and Behavior. e01080. PMID 30136422 DOI: 10.1002/Brb3.1080  0.663
2018 Wolters EE, Golla SSV, Timmers T, Ossenkoppele R, van der Weijden CWJ, Scheltens P, Schwarte L, Schuit RC, Windhorst AD, Barkhof F, Yaqub M, Lammertsma AA, Boellaard R, van Berckel BNM. A novel partial volume correction method for accurate quantification of [F] flortaucipir in the hippocampus. Ejnmmi Research. 8: 79. PMID 30112620 DOI: 10.1186/S13550-018-0432-2  0.372
2018 Reus LM, Vijverberg EG, Tijms BM, Kate MT, Gossink F, Krudop WA, Campo MD, Teunissen CE, Barkhof F, van der Flier WM, Visser PJ, Dols A, Pijnenburg YA. Disease trajectories in behavioural variant frontotemporal dementia, primary psychiatric and other neurodegenerative disorders presenting with behavioural change. Journal of Psychiatric Research. 104: 183-191. PMID 30103065 DOI: 10.1016/J.Jpsychires.2018.07.014  0.332
2018 Slot RER, Verfaillie SCJ, Overbeek JM, Timmers T, Wesselman LMP, Teunissen CE, Dols A, Bouwman FH, Prins ND, Barkhof F, Lammertsma AA, Van Berckel BNM, Scheltens P, Sikkes SAM, Van der Flier WM. Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results. Alzheimer's Research & Therapy. 10: 76. PMID 30081935 DOI: 10.1186/S13195-018-0390-Y  0.416
2018 Konijnenberg E, Carter SF, Ten Kate M, den Braber A, Tomassen J, Amadi C, Wesselman L, Nguyen HT, van de Kreeke JA, Yaqub M, Demuru M, Mulder SD, Hillebrand A, Bouwman FH, Teunissen CE, ... ... Barkhof F, et al. The EMIF-AD PreclinAD study: study design and baseline cohort overview. Alzheimer's Research & Therapy. 10: 75. PMID 30075734 DOI: 10.1186/S13195-018-0406-7  0.483
2018 de Wilde A, van Buchem MM, Otten RHJ, Bouwman F, Stephens A, Barkhof F, Scheltens P, van der Flier WM. Disclosure of amyloid positron emission tomography results to individuals without dementia: a systematic review. Alzheimer's Research & Therapy. 10: 72. PMID 30055660 DOI: 10.1186/S13195-018-0398-3  0.448
2018 Groot C, Tolboom N, Ikonomovic MD, Lammertsma AA, Boon BDC, Barkhof F, Scheltens P, Klunk WE, Rozemuller AJM, Ossenkoppele R, van Berckel BNM. Quantitative PET and Histology of Brain Biopsy Reveal Lack of Selective Pittsburgh Compound-B Binding to Intracerebral Amyloidoma. Journal of Alzheimer's Disease : Jad. PMID 30040724 DOI: 10.3233/Jad-180316  0.408
2018 Shu N, Duan Y, Huang J, Ren Z, Liu Z, Dong H, Barkhof F, Li K, Liu Y. Progressive brain rich-club network disruption from clinically isolated syndrome towards multiple sclerosis. Neuroimage. Clinical. 19: 232-239. PMID 30035017 DOI: 10.1016/J.Nicl.2018.03.034  0.367
2018 Scheltens NME, van der Weijden K, Adriaanse SM, van Assema D, Oomen PP, Krudop WA, Lammertsma AA, Barkhof F, Koene T, Teunissen CE, Scheltens P, van der Flier WM, Pijnenburg YAL, Yaqub M, Ossenkoppele R, et al. Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease. Neuroimage. Clinical. 19: 625-632. PMID 29984170 DOI: 10.1016/J.Nicl.2018.05.024  0.468
2018 Amiri H, de Sitter A, Bendfeldt K, Battaglini M, Gandini Wheeler-Kingshott CAM, Calabrese M, Geurts JJG, Rocca MA, Sastre-Garriga J, Enzinger C, de Stefano N, Filippi M, Rovira Á, Barkhof F, Vrenken H, et al. Urgent challenges in quantification and interpretation of brain grey matter atrophy in individual MS patients using MRI. Neuroimage. Clinical. 19: 466-475. PMID 29984155 DOI: 10.1016/J.Nicl.2018.04.023  0.576
2018 Bos I, Vos S, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni G, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird A, Dobson R, Legido-Quigley C, Sleegers K, ... ... Barkhof F, et al. The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics. Alzheimer's Research & Therapy. 10: 64. PMID 29980228 DOI: 10.1186/S13195-018-0396-5  0.436
2018 Prados F, Barkhof F. Spinal cord atrophy rates: Ready for prime time in multiple sclerosis clinical trials? Neurology. PMID 29950433 DOI: 10.1212/Wnl.0000000000005873  0.358
2018 Hagens MHJ, Burggraaff J, Kilsdonk ID, de Vos ML, Cawley N, Sbardella E, Andelova M, Amann M, Lieb JM, Pantano P, Lissenberg-Witte BI, Killestein J, Oreja-Guevara C, Ciccarelli O, Gasperini C, ... ... Barkhof F, et al. Three-Tesla MRI does not improve the diagnosis of multiple sclerosis: A multicenter study. Neurology. PMID 29925550 DOI: 10.1212/Wnl.0000000000005825  0.393
2018 Tolonen A, Rhodius-Meester HFM, Bruun M, Koikkalainen J, Barkhof F, Lemstra AW, Koene T, Scheltens P, Teunissen CE, Tong T, Guerrero R, Schuh A, Ledig C, Baroni M, Rueckert D, et al. Data-Driven Differential Diagnosis of Dementia Using Multiclass Disease State Index Classifier. Frontiers in Aging Neuroscience. 10: 111. PMID 29922145 DOI: 10.3389/Fnagi.2018.00111  0.461
2018 de Wilde A, van der Flier WM, Pelkmans W, Bouwman F, Verwer J, Groot C, van Buchem MM, Zwan M, Ossenkoppele R, Yaqub M, Kunneman M, Smets EMA, Barkhof F, Lammertsma AA, Stephens A, et al. Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project. Jama Neurology. PMID 29889941 DOI: 10.1001/Jamaneurol.2018.1346  0.414
2018 Leeuwis AE, Prins ND, Hooghiemstra AM, Benedictus MR, Scheltens P, Barkhof F, van der Flier WM. Microbleeds are associated with depressive symptoms in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 112-120. PMID 29780860 DOI: 10.1016/J.Dadm.2017.11.006  0.378
2018 Eshaghi A, Marinescu RV, Young AL, Firth NC, Prados F, Jorge Cardoso M, Tur C, De Angelis F, Cawley N, Brownlee WJ, De Stefano N, Laura Stromillo M, Battaglini M, Ruggieri S, Gasperini C, ... ... Barkhof F, et al. Progression of regional grey matter atrophy in multiple sclerosis. Brain : a Journal of Neurology. PMID 29741648 DOI: 10.1093/Brain/Awy088  0.585
2018 Liu Y, Duan Y, Dong H, Barkhof F, Li K, Shu N. Disrupted Module Efficiency of Structural and Functional Brain Connectomes in Clinically Isolated Syndrome and Multiple Sclerosis. Frontiers in Human Neuroscience. 12: 138. PMID 29692717 DOI: 10.3389/Fnhum.2018.00138  0.34
2018 Bouts MJRJ, Möller C, Hafkemeijer A, van Swieten JC, Dopper E, van der Flier WM, Vrenken H, Wink AM, Pijnenburg YAL, Scheltens P, Barkhof F, Schouten TM, de Vos F, Feis RA, van der Grond J, et al. Single Subject Classification of Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Anatomical, Diffusion Tensor, and Resting-State Functional Magnetic Resonance Imaging. Journal of Alzheimer's Disease : Jad. PMID 29614652 DOI: 10.3233/Jad-170893  0.703
2018 Verfaillie SCJ, Slot RER, Dicks E, Prins ND, Overbeek JM, Teunissen CE, Scheltens P, Barkhof F, van der Flier WM, Tijms BM. A more randomly organized grey matter network is associated with deteriorating language and global cognition in individuals with subjective cognitive decline. Human Brain Mapping. PMID 29602212 DOI: 10.1002/Hbm.24065  0.462
2018 Ten Kate M, Visser PJ, Bakardjian H, Barkhof F, Sikkes SAM, van der Flier WM, Scheltens P, Hampel H, Habert MO, Dubois B, Tijms BM. Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults. Frontiers in Aging Neuroscience. 10: 67. PMID 29599717 DOI: 10.3389/Fnagi.2018.00067  0.49
2018 Leijenaar JF, Groeneveld GJ, van der Flier WM, Scheltens P, Klaassen ES, Weinstein HC, Biessels GJ, Barkhof F, Prins ND. Symptomatic Treatment of Vascular Cognitive Impairment (STREAM-VCI): Protocol for a Cross-Over Trial. Jmir Research Protocols. 7: e80. PMID 29559423 DOI: 10.2196/Resprot.9192  0.438
2018 Haller S, Vernooij MW, Kuijer JPA, Larsson EM, Jäger HR, Barkhof F. Cerebral Microbleeds: Imaging and Clinical Significance. Radiology. 287: 11-28. PMID 29558307 DOI: 10.1148/Radiol.2018170803  0.351
2018 Wijburg MT, Kleerekooper I, Lissenberg-Witte BI, de Vos M, Warnke C, Uitdehaag BMJ, Barkhof F, Killestein J, Wattjes MP. Association of Progressive Multifocal Leukoencephalopathy Lesion Volume With JC Virus Polymerase Chain Reaction Results in Cerebrospinal Fluid of Natalizumab-Treated Patients With Multiple Sclerosis. Jama Neurology. PMID 29532061 DOI: 10.1001/Jamaneurol.2018.0094  0.36
2018 Geraldes R, Ciccarelli O, Barkhof F, De Stefano N, Enzinger C, Filippi M, Hofer M, Paul F, Preziosa P, Rovira A, DeLuca GC, Kappos L, Yousry T, Fazekas F, Frederiksen J, et al. The current role of MRI in differentiating multiple sclerosis from its imaging mimics. Nature Reviews. Neurology. PMID 29521337 DOI: 10.1038/Nrneurol.2018.14  0.388
2018 Cortese R, Magnollay L, Tur C, Abdel-Aziz K, Jacob A, De Angelis F, Yiannakas MC, Prados F, Ourselin S, Yousry TA, Barkhof F, Ciccarelli O. Value of the central vein sign at 3T to differentiate MS from seropositive NMOSD. Neurology. PMID 29514948 DOI: 10.1212/Wnl.0000000000005256  0.328
2018 Ten Kate M, Sudre CH, den Braber A, Konijnenberg E, Nivard MG, Cardoso MJ, Scheltens P, Ourselin S, Boomsma DI, Barkhof F, Visser PJ. White matter hyperintensities and vascular risk factors in monozygotic twins. Neurobiology of Aging. 66: 40-48. PMID 29505954 DOI: 10.1016/J.Neurobiolaging.2018.02.002  0.386
2018 Vos SB, Micallef C, Barkhof F, Hill A, Winston GP, Ourselin S, Duncan JS. Evaluation of prospective motion correction of high-resolution 3D-T2-FLAIR acquisitions in epilepsy patients. Journal of Neuroradiology. Journal De Neuroradiologie. PMID 29505841 DOI: 10.1016/J.Neurad.2018.02.007  0.32
2018 Rhodius-Meester HFM, Liedes H, Koene T, Lemstra AW, Teunissen CE, Barkhof F, Scheltens P, van Gils M, Lötjönen J, van der Flier WM. Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease. Alzheimer's Research & Therapy. 10: 23. PMID 29458426 DOI: 10.1186/S13195-018-0348-0  0.457
2018 Hendriks EJ, Habets EJJ, Taphoorn MJB, Douw L, Zwinderman AH, Vandertop WP, Barkhof F, Klein M, De Witt Hamer PC. Linking late cognitive outcome with glioma surgery location using resection cavity maps. Human Brain Mapping. PMID 29380489 DOI: 10.1002/Hbm.23986  0.325
2018 Eshaghi A, Prados F, Brownlee W, Altmann DR, Tur C, Cardoso MJ, De Angelis F, van de Pavert SH, Cawley N, De Stefano N, Stromillo ML, Battaglini M, Ruggieri S, Gasperini C, Filippi M, ... ... Barkhof F, et al. Deep grey matter volume loss drives disability worsening in multiple sclerosis. Annals of Neurology. PMID 29331092 DOI: 10.1002/Ana.25145  0.357
2018 Hagens MH, Burggraaff J, Kilsdonk ID, Ruggieri S, Collorone S, Cortese R, Cawley N, Sbardella E, Andelova M, Amann M, Lieb JM, Pantano P, Lissenberg-Witte BI, Killestein J, Oreja-Guevara C, ... ... Barkhof F, et al. Impact of 3 Tesla MRI on interobserver agreement in clinically isolated syndrome: A MAGNIMS multicentre study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517751647. PMID 29327668 DOI: 10.1177/1352458517751647  0.338
2018 Rimkus CM, Schoonheim MM, Steenwijk MD, Vrenken H, Eijlers AJ, Killestein J, Wattjes MP, Leite CC, Barkhof F, Tijms BM. Gray matter networks and cognitive impairment in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517751650. PMID 29320933 DOI: 10.1177/1352458517751650  0.362
2018 EMANUEL AL, DUINKERKEN EV, WATTJES MP, KLEIN M, BARKHOF F, SNOEK FJ, ERINGA EC, IJZERMAN R, SERNE EH. The Presence of Cerebral White Matter Lesions and Lower Skin Microvascular Perfusion Predict Decline in General Cognitive Ability in Type 1 Diabetes Patients but Not in Healthy Controls Diabetes. 67: 203-LB. DOI: 10.2337/Db18-203-Lb  0.344
2018 de Stefano N, Achiron A, Barkhof F, Chan A, Derfuss T, Hodgkinson S, Leocani L, Montalban X, Prat A, Schmierer K, Sellebjerg F, Vermersch P, Wiendl H, Keller B, Roy S. THUR 174 The magnify-ms study: mavenclad® tablets in active rms Journal of Neurology, Neurosurgery & Psychiatry. 89: A23.1-A23. DOI: 10.1136/Jnnp-2018-Abn.81  0.394
2018 Leeuwis AE, Weaver NA, Biesbroek JM, Kuijf HJ, Hooghiemstra AM, Prins ND, Scheltens P, Barkhof F, Flier WMVd, Biessels GJ. O1-14-04: Impact Of White Matter Hyperintensity Location On Depressive Symptoms In Memory Clinic Patients: A Lesion-Symptom Mapping Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.3050  0.404
2018 Leeuw FAd, Tijms BM, Peeters CFW, Kester MI, Scheltens P, Duijn CMv, Barkhof F, Teunissen CE, Flier WMVd. P1-297: Metabolic Blood-Based Biomarkers Relate To Brain Atrophy And White Matter Hyperintensities In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.303  0.465
2018 Kate Mt, Dicks E, Flier WMVd, Teunissen CE, Scheltens P, Barkhof F, Visser PJ, Tijms BM, Initiative ADN, Cohort AD. O5-01-03: Atrophy Subtypes In Alzheimer'S Disease Identified Through Non-Negative Matrix Factorization Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2997  0.406
2018 Loenhoud ACv, Flier WMVd, Wink AM, Dicks E, Groot C, Twisk JW, Barkhof F, Scheltens P, Ossenkoppele R. The Use Of Residual Methods To Capture Cognitive Reserve And Study Clinical Progression In Alzheimer’S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2987  0.446
2018 Maurik ISv, Vos SJB, Bos I, Bouwman FH, Tijms BM, Teunissen CE, Barkhof F, Scheltens P, Palmqvist S, Hansson O, Visser PJ, Berkhof J, Flier WMVd. O2-15-04: Robust Individualized Prediction Models Which Are Applicable Across Different Cohorts Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2727  0.338
2018 Pijnenburg YAL, Vijverberg E, Krudop WA, Gossink FT, Prins ND, Schouws S, Teunissen CE, Barkhof F, Berckel BNMv, Stek ML, Scheltens P, Dols A. O2-14-04: Identifying Behavioral Variant Frontotemporal Dementia Among Patients With A Late-Onset Frontal Lobe Syndrome: Summary Results Of The Lof Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2721  0.411
2018 Collij L, Heeman F, Konijnenberg E, Braber Ad, Yaqub MM, Visser PJ, Wink AM, Scheltens P, Boellaard R, Berckel BNMv, Schmidt ME, Barkhof F, Alves IL. Extension And Validation Of An Amyloid Staging Model: Associations With Clinical Measures Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2692  0.388
2018 Hong S, Dobricic V, Smith RG, Küçükali F, Kilpert F, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, ... ... Barkhof F, et al. F1-02-04: Genomics And Epigenomics Analyses In The Emif-Ad Multimodal Biomarker Discovery Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2310  0.379
2018 Bos I, Vos SJB, Verhey FRJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, Popp J, Martinez-Lage P, Lleó A, Johannsen P, Freund-Levi Y, ... ... Barkhof F, et al. F1-02-01: RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT-LIGHT AND YKL-40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2307  0.44
2018 Timmers T, Ossenkoppele R, Wolters EE, Visser D, Barkhof F, Golla SSV, Boellaard R, Windhorst AD, Scheltens P, Flier WMVd, Berckel BNMv. Ic-P-222: [18F]Av1451 Pet In Relation To Atrophy Across The Alzheimer'S Disease Spectrum Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2289  0.403
2018 Loenhoud ACv, Flier WMVd, Wink AM, Dicks E, Groot C, Twisk JW, Barkhof F, Scheltens P, Ossenkoppele R. Disease-Stage Specific Relationship Between Cognitive Reserve And Clinical Progression In Alzheimer’S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2259  0.448
2018 Jonkman LE, Galis Y, Kaai E, Weerd Lvd, Pouwels PJW, Barkhof F, Rozemuller AM, Geurts JJ, Berg WDJVd. The Normal Aging Brain Collection Amsterdam (Nabca): A Comprehensive Collection Of Postmortem Imaging, Neuropathological And Morphometric Datasets Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2188  0.314
2018 Singleton EH, Pijnenburg YAL, Sudre CH, Kochova E, Groot C, Papma JM, Ourselin S, Swieten JCv, Barkhof F, Cardoso MJ, Scheltens P, Rabinovici GD, Ossenkoppele R. Ic-P-110: Patterns Of Glucose Hypometabolism, Subcortical Atrophy And White Matter Hyperintensities In The Behavioral Variant Of Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2176  0.429
2018 Groot C, Yeo T, Vogel JW, Zhang EX, Suna N, Crane PK, Rabinovici GD, Mormino BC, Pijnenburg YAL, Barkhof F, Scheltens P, Flier WMVd, Ossenkoppele R. Ic-P-093: Latent Atrophy Factors In Posterior Cortical Atrophy Relate To Specific Cognitive Impairments Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2157  0.433
2018 Braber Ad, Stickney K, Ent Dv', Kate Mt, Konijnenberg E, Tomassen J, Barkhof F, Berckel BNMv, Boomsma DI, Geus Ed, Scheltens P, Visser PJ. Ic-P-066: White Matter Microstructure And Amyloid Aggregation In Cognitively Healthy, Elderly Identical Twins Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2131  0.473
2018 Collij L, Konijnenberg E, Reimand J, Kate Mt, Braber Ad, Alves IL, Zwan MD, Yaqub MM, Assema Dv, Wink AM, Lammertsma AA, Scheltens P, Visser PJ, Barkhof F, Berckel BNMv. Assessment Of Early Amyloid Pathology Using [18F]Flutemetamol Positron Emission Tomography: Comparing Visual Read, Semi-Quantitative And Quantitative Methods Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2069  0.383
2018 Tijms BM, Dicks E, Scheltens P, Barkhof F, Flier WMVd. Ic-06-05: Loss Of Grey Matter Connectivity In The Precuneus Is Associated With Faster Atrophy Rates In Preclinical Alzheimer'S Disease Alzheimers & Dementia. 14: 13. DOI: 10.1016/J.Jalz.2018.06.2058  0.44
2018 Garbarino S, Lorenzi M, Vinke E, Marinescu RV, Oxtoby NP, Eshaghi A, Ikram MA, Niessen WJ, Ciccarelli O, Barkhof F, Vernooij MW, Alexander DC, Initiative ADN. P3-436: Mechanistic Profiles Of Neurodegeneration: A Study In Alzheimer'S Disease, Healthy Ageing And Primary Progressive Multiple Sclerosis Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1799  0.355
2018 Dicks E, He Y, Beg F, Biessels GJ, Carmeli C, Chen G, Çiftçi K, Dai Z, Dellen EV, Dyrba M, Friedman EJ, Haan Wd, Jalili M, Jeong J, Jeong Y, ... ... Barkhof F, et al. Ic-P-032: Influence Of Network Construction Methods On Path Length Values In Alzheimer'S Disease: A Multi-Study Analysis Of Mri Connectivity Studies Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1703  0.438
2018 Jutten RJ, Dicks E, Vermaat LEW, Barkhof F, Scheltens P, Tijms BM, Sikkes SAM. P3-277: Impairment In Complex Activities Of Daily Living Is Related To Neurodegeneration In Alzheimer'S Disease Specific Regions Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1637  0.441
2018 Kim M, Snowden SG, Ahmad T, Westwood S, Baird AL, Proitsi P, Nevado-Holgado AJ, Hye A, Ashton NJ, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, ... ... Barkhof F, et al. P3-233: PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER\textquotesingleS DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1592  0.439
2018 Legdeur N, Badissi M, Collij L, Heeman F, Berckel BNMv, Barkhof F, Scheltens P, Muller M, Maier AB, Visser PJ. P3-216: Is The Relation Between Blood Pressure And Cognition Dependent On Amyloid Pathology Or Physical Performance? Results Of The Emif-Ad 90+ Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1575  0.436
2018 Brugulat-Serrat A, Salvadó G, Sudre CH, Grau O, Falcon C, Sánchez-Benavides G, Gramunt N, Cardoso MJ, Barkhof F, Molinuevo JL, Gispert JD. P2-505: Regional Distribution Of White Matter Hyperintensity Correlates With Cognition In The Alfa Cohort Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1199  0.313
2018 Rhodius-Meester HFM, Bruun M, Baroni M, Gjerum L, Remes AM, Urhemaa T, Tolonen A, Rueckert D, Gils Mv, Lemstra E, Barkhof F, Frederiksen KS, Waldemar G, Scheltens P, Soininen H, et al. Different combinations of diagnostic tests discriminate specific subtypes of dementia Alzheimers & Dementia. 10: 820-821. DOI: 10.1016/J.Jalz.2018.06.1039  0.396
2018 Leijenaar JF, Klaassen ES, Leeuwis AE, Groeneveld GJ, Flier WMVd, Scheltens P, Weinstein HC, Biessels GJ, Barkhof F, Prins ND. Methylphenidate Improves Executive Functioning In Patients With Vascular Cognitive Impairment: First Results Of The Stream-Vci Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.017  0.437
2017 Filippi M, Preziosa P, Meani A, Ciccarelli O, Mesaros S, Rovira A, Frederiksen J, Enzinger C, Barkhof F, Gasperini C, Brownlee W, Drulovic J, Montalban X, Cramer SP, Pichler A, et al. Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study. The Lancet. Neurology. PMID 29275979 DOI: 10.1016/S1474-4422(17)30469-6  0.398
2017 Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. The Lancet. Neurology. PMID 29275977 DOI: 10.1016/S1474-4422(17)30470-2  0.357
2017 Groot C, van Loenhoud AC, Barkhof F, van Berckel BNM, Koene T, Teunissen CC, Scheltens P, van der Flier WM, Ossenkoppele R. Differential effects of cognitive reserve and brain reserve on cognition in Alzheimer disease. Neurology. PMID 29237798 DOI: 10.1212/Wnl.0000000000004802  0.466
2017 Leijenaar JF, van Maurik IS, Kuijer JPA, van der Flier WM, Scheltens P, Barkhof F, Prins ND. Lower cerebral blood flow in subjects with Alzheimer's dementia, mild cognitive impairment, and subjective cognitive decline using two-dimensional phase-contrast magnetic resonance imaging. Alzheimer's & Dementia (Amsterdam, Netherlands). 9: 76-83. PMID 29234724 DOI: 10.1016/J.Dadm.2017.10.001  0.487
2017 Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, et al. A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease. Alzheimer's Research & Therapy. 9: 95. PMID 29221491 DOI: 10.1186/S13195-017-0318-Y  0.422
2017 Wattjes MP, Wijburg MT, Eijk JV, Frequin S, Uitdehaag BMJ, Barkhof F, Warnke C, Killestein J. Inflammatory natalizumab-associated PML: baseline characteristics, lesion evolution and relation with PML-IRIS. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29142146 DOI: 10.1136/Jnnp-2017-316886  0.31
2017 Dicks E, Tijms BM, Ten Kate M, Gouw AA, Benedictus MR, Teunissen CE, Barkhof F, Scheltens P, van der Flier WM. Gray matter network measures are associated with cognitive decline in mild cognitive impairment. Neurobiology of Aging. 61: 198-206. PMID 29111486 DOI: 10.1016/J.Neurobiolaging.2017.09.029  0.477
2017 Dekker I, Sombekke MH, Witte BI, Geurts JJ, Barkhof F, Uitdehaag BM, Killestein J, Wattjes MP. Asymptomatic spinal cord lesions do not predict the time to disability in patients with early multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517736147. PMID 29106327 DOI: 10.1177/1352458517736147  0.546
2017 van Maurik IS, Zwan MD, Tijms BM, Bouwman FH, Teunissen CE, Scheltens P, Wattjes MP, Barkhof F, Berkhof J, van der Flier WM. Interpreting Biomarker Results in Individual Patients With Mild Cognitive Impairment in the Alzheimer's Biomarkers in Daily Practice (ABIDE) Project. Jama Neurology. PMID 29049480 DOI: 10.1001/Jamaneurol.2017.2712  0.491
2017 Moccia M, de Stefano N, Barkhof F. Imaging outcome measures for progressive multiple sclerosis trials. Multiple Sclerosis (Houndmills, Basingstoke, England). 23: 1614-1626. PMID 29041865 DOI: 10.1177/1352458517729456  0.397
2017 Tijms BM, Ten Kate M, Gouw AA, Borta A, Verfaillie S, Teunissen CE, Scheltens P, Barkhof F, van der Flier WM. Gray matter networks and clinical progression in subjects with predementia Alzheimer's disease. Neurobiology of Aging. 61: 75-81. PMID 29040871 DOI: 10.1016/J.Neurobiolaging.2017.09.011  0.508
2017 Verfaillie SCJ, Slot RE, Tijms BM, Bouwman F, Benedictus MR, Overbeek JM, Koene T, Vrenken H, Scheltens P, Barkhof F, van der Flier WM. Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory. Neurobiology of Aging. PMID 29029762 DOI: 10.1016/J.Neurobiolaging.2017.09.009  0.476
2017 Martens RM, Bechten A, Ingala S, van Schijndel RA, Machado VB, de Jong MC, Sanchez E, Purcell D, Arrighi MH, Brashear RH, Wattjes MP, Barkhof F. The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients: An interobserver study. European Radiology. PMID 28956123 DOI: 10.1007/S00330-017-5022-6  0.379
2017 de Sitter A, Steenwijk MD, Ruet A, Versteeg A, Liu Y, van Schijndel RA, Pouwels PJW, Kilsdonk ID, Cover KS, van Dijk BW, Ropele S, Rocca MA, Yiannakas M, Wattjes MP, Damangir S, ... ... Barkhof F, et al. Performance of five research-domain automated WM lesion segmentation methods in a multi-center MS study. Neuroimage. PMID 28899746 DOI: 10.1016/J.Neuroimage.2017.09.011  0.336
2017 Ten Kate M, Barkhof F, Visser PJ, Teunissen CE, Scheltens P, van der Flier WM, Tijms BM. Amyloid-independent atrophy patterns predict time to progression to dementia in mild cognitive impairment. Alzheimer's Research & Therapy. 9: 73. PMID 28899429 DOI: 10.1186/S13195-017-0299-X  0.517
2017 Steenwijk MD, Amiri H, Schoonheim MM, de Sitter A, Barkhof F, Pouwels PJW, Vrenken H. Agreement of MSmetrix with established methods for measuring cross-sectional and longitudinal brain atrophy. Neuroimage. Clinical. 15: 843-853. PMID 28794970 DOI: 10.1016/J.Nicl.2017.06.034  0.332
2017 Liu Y, Jiang X, Butzkueven H, Duan Y, Huang J, Ren Z, Dong H, Shi FD, Barkhof F, Li K, Wang J. Multimodal characterization of gray matter alterations in neuromyelitis optica. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517721053. PMID 28741987 DOI: 10.1177/1352458517721053  0.36
2017 Frisoni GB, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K, Démonet JF, Garibotto V, Giannakopoulos P, Gietl A, Hansson O, Herholz K, Jack CR, Nobili F, Nordberg A, et al. Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers. The Lancet. Neurology. 16: 661-676. PMID 28721928 DOI: 10.1016/S1474-4422(17)30159-X  0.444
2017 Liu Y, Duan Y, Huang J, Ren Z, Liu Z, Dong H, Weiler F, Hahn HK, Shi FD, Butzkueven H, Barkhof F, Li K. Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS. European Radiology. PMID 28667482 DOI: 10.1007/S00330-017-4921-X  0.323
2017 Tong T, Ledig C, Guerrero R, Schuh A, Koikkalainen J, Tolonen A, Rhodius H, Barkhof F, Tijms B, Lemstra AW, Soininen H, Remes AM, Waldemar G, Hasselbalch S, Mecocci P, et al. Five-class differential diagnostics of neurodegenerative diseases using random undersampling boosting. Neuroimage. Clinical. 15: 613-624. PMID 28664032 DOI: 10.1016/J.Nicl.2017.06.012  0.322
2017 van Loenhoud AC, Wink AM, Groot C, Verfaillie SCJ, Twisk J, Barkhof F, van Berckel B, Scheltens P, van der Flier WM, Ossenkoppele R. A neuroimaging approach to capture cognitive reserve: Application to Alzheimer's disease. Human Brain Mapping. PMID 28631336 DOI: 10.1002/Hbm.23695  0.705
2017 Cavedo E, Lista S, Rojkova K, Andrea Chiesa P, Houot M, Brueggen K, Blautzik J, Bokde ALW, Dubois B, Barkhof F, Pouwels PJW, Teipel S, Hampel H. Disrupted white matter structural networks in healthy older adults APOE ε4 carriers - An International Multicenter DTI Study. Neuroscience. PMID 28596117 DOI: 10.1016/J.Neuroscience.2017.05.048  0.363
2017 Vrij-van den Bos S, Hol JA, La Piana R, Harting I, Vanderver A, Barkhof F, Cayami F, van Wieringen WN, Pouwels PJW, van der Knaap MS, Bernard G, Wolf NI. 4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System. Neuropediatrics. 48: 152-160. PMID 28561206 DOI: 10.1055/S-0037-1599141  0.536
2017 Rhodius-Meester HFM, Benedictus MR, Wattjes MP, Barkhof F, Scheltens P, Muller M, van der Flier WM. MRI Visual Ratings of Brain Atrophy and White Matter Hyperintensities across the Spectrum of Cognitive Decline Are Differently Affected by Age and Diagnosis. Frontiers in Aging Neuroscience. 9: 117. PMID 28536518 DOI: 10.3389/Fnagi.2017.00117  0.47
2017 Harper L, Bouwman F, Burton EJ, Barkhof F, Scheltens P, O'Brien JT, Fox NC, Ridgway GR, Schott JM. Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28473626 DOI: 10.1136/Jnnp-2016-314978  0.481
2017 Meijer KA, Eijlers AJC, Douw L, Uitdehaag BMJ, Barkhof F, Geurts JJG, Schoonheim MM. Increased connectivity of hub networks and cognitive impairment in multiple sclerosis. Neurology. PMID 28468841 DOI: 10.1212/Wnl.0000000000003982  0.551
2017 Hagens MH, Killestein J, Yaqub MM, van Dongen GA, Lammertsma AA, Barkhof F, van Berckel BN. Cerebral rituximab uptake in multiple sclerosis: A (89)Zr-immunoPET pilot study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517704507. PMID 28443358 DOI: 10.1177/1352458517704507  0.339
2017 van Duinkerken E, Schoonheim MM, IJzerman RG, Moll AC, Landeira-Fernandez J, Klein M, Diamant M, Snoek FJ, Barkhof F, Wink AM. Altered eigenvector centrality is related to local resting-state network functional connectivity in patients with longstanding type 1 diabetes mellitus. Human Brain Mapping. PMID 28429383 DOI: 10.1002/Hbm.23617  0.633
2017 Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Koek HL, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ. Vascular Cognitive Impairment in a Memory Clinic Population: Rationale and Design of the "Utrecht-Amsterdam Clinical Features and Prognosis in Vascular Cognitive Impairment" (TRACE-VCI) Study. Jmir Research Protocols. 6: e60. PMID 28428166 DOI: 10.2196/Resprot.6864  0.449
2017 Scheltens NME, Tijms BM, Koene T, Barkhof F, Teunissen CE, Wolfsgruber S, Wagner M, Kornhuber J, Peters O, Cohn-Sheehy BI, Rabinovici GD, Miller BL, Kramer JH, Scheltens P, van der Flier WM, et al. Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28427934 DOI: 10.1016/J.Jalz.2017.03.002  0.486
2017 Klauser AM, Wiebenga OT, Eijlers AJ, Schoonheim MM, Uitdehaag BM, Barkhof F, Pouwels PJ, Geurts JJ. Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517702534. PMID 28406063 DOI: 10.1177/1352458517702534  0.57
2017 Ten Kate M, Barkhof F, Boccardi M, Visser PJ, Jack CR, Lovblad KO, Frisoni GB, Scheltens P. Clinical validity of medial temporal atrophy as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework. Neurobiology of Aging. 52: 167-182.e1. PMID 28317647 DOI: 10.1016/J.Neurobiolaging.2016.05.024  0.45
2017 Ketter N, Brashear HR, Bogert J, Di J, Miaux Y, Gass A, Purcell DD, Barkhof F, Arrighi HM. Central Review of Amyloid-Related Imaging Abnormalities in Two Phase III Clinical Trials of Bapineuzumab in Mild-To-Moderate Alzheimer's Disease Patients. Journal of Alzheimer's Disease : Jad. PMID 28269765 DOI: 10.3233/Jad-160216  0.354
2017 Vrij-van den Bos S, Hol JA, La Piana R, Harting I, Vanderver A, Barkhof F, Cayami F, van Wieringen WN, Pouwels PJ, van der Knaap MS, Bernard G, Wolf NI. 4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System. Neuropediatrics. PMID 28249300 DOI: 10.1055/s-0037-1599141  0.473
2017 de Wilde A, van Maurik IS, Kunneman M, Bouwman F, Zwan M, Willemse EA, Biessels GJ, Minkman M, Pel R, Schoonenboom NS, Smets EM, Wattjes MP, Barkhof F, Stephens A, van Lier EJ, et al. Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design. Alzheimer's & Dementia (Amsterdam, Netherlands). 6: 143-151. PMID 28239639 DOI: 10.1016/J.Dadm.2017.01.003  0.461
2017 Sudre CH, Cardoso MJ, Frost C, Barnes J, Barkhof F, Fox N, Ourselin S. APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis. Neurobiology of Aging. 53: 67-75. PMID 28235680 DOI: 10.1016/J.Neurobiolaging.2017.01.014  0.387
2017 Eijlers AJ, Meijer KA, Wassenaar TM, Steenwijk MD, Uitdehaag BM, Barkhof F, Wink AM, Geurts JJ, Schoonheim MM. Increased default-mode network centrality in cognitively impaired multiple sclerosis patients. Neurology. PMID 28179464 DOI: 10.1212/Wnl.0000000000003689  0.721
2017 Derks J, Dirkson AR, de Witt Hamer PC, van Geest Q, Hulst HE, Barkhof F, Pouwels PJ, Geurts JJ, Reijneveld JC, Douw L. Connectomic profile and clinical phenotype in newly diagnosed glioma patients. Neuroimage. Clinical. 14: 87-96. PMID 28154795 DOI: 10.1016/J.Nicl.2017.01.007  0.533
2017 van Zanten SE, Baugh J, Chaney B, De Jongh D, Aliaga ES, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, et al. Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease. Journal of Neuro-Oncology. PMID 28110411 DOI: 10.1007/S11060-016-2363-Y  0.305
2017 Bechten A, Wattjes MP, Purcell DD, Aliaga ES, Daams M, Brashear HR, Arrighi HM, Barkhof F. Validation of an MRI Rating Scale for Amyloid-Related Imaging Abnormalities. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 28102639 DOI: 10.1111/Jon.12422  0.337
2017 Wilde Ad, Pelkmans W, Bouwman FH, Verwer J, Groot C, Buchem Mv, Zwan MD, Ossenkoppele R, Yaqub MM, Kunneman M, Smets EM, Barkhof F, Lammertsma AA, Stephens A, Lier Ev, et al. The Impact Of Amyloid Pet On Diagnosis And Patient Management In An Unselected Memory Clinic Cohort: The Abide Project Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.08.004  0.393
2017 Frisoni GB, Barkhof F, Farrar G, Raffa N, Gismondi R, Schmidt ME, Berkhof J, Boccardi M, Walker Z, Scheltens P, Schott JM, Molinuevo JL, Vellas B, Jessen F, Nordberg A, et al. THE AMYPAD-DX CONTROLLED TRIAL ON THE DIAGNOSTIC VALUE OF AMYLOID PET Alzheimer's & Dementia. 13: P1523. DOI: 10.1016/J.Jalz.2017.07.653  0.379
2017 Jansen IE, Teunissen CE, Barkhof F, Scheltens P, Posthuma D, van der Flier WM. ESTABLISHING THE EFFECT OF CODING VARIANTS ON ALZHEIMER’S DISEASE RELATED ENDOPHENOTYPES Alzheimer's & Dementia. 13: P1487-P1488. DOI: 10.1016/J.Jalz.2017.07.569  0.366
2017 van Loenhoud AC, van der Flier WM, Wink AM, Groot C, Twisk JW, van Berckel BN, Barkhof F, Scheltens P, Ossenkoppele R. PREDICTING PROGRESSION IN PRE-DEMENTIA STAGES OF ALZHEIMER’S DISEASE WITH A NEUROIMAGING MEASURE OF COGNITIVE RESERVE Alzheimer's & Dementia. 13: P581-P582. DOI: 10.1016/J.Jalz.2017.07.206  0.677
2017 Rhodius-Meester HFM, Liedes H, Wolfsgruber S, Coll-Padros N, Koikkalainen J, Kornhuber J, Peters O, Jessen F, Kleineidam L, Molinuevo JL, Rami L, Teunissen CE, Barkhof F, Sikkes SAM, Wesselman LMP, et al. Prognosis Of Clinical Progression In Subjective Cognitive Decline Using A Clinical Decision Support System Alzheimers & Dementia. 13: 579. DOI: 10.1016/J.Jalz.2017.07.203  0.424
2017 Slot RER, Verfaillie SCJ, Overbeek JM, Timmers T, Wesselman LMP, Bouwman FH, Prins ND, Teunissen CE, Dols A, Barkhof F, Berckel BNMv, Scheltens P, Sikkes SAM, Flier WMvd. Characterizing Individuals With Subjective Cognitive Decline: The Subjective Cognitive Impairment Cohort (Science) Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.143  0.424
2017 Maurik ISv, Slot RER, Verfaillie SCJ, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Wattjes MP, Berkhof J, Flier WMvd. Biomarker-Based Personalized Risk Estimates For Patients With Subjective Cognitive Decline Alzheimers & Dementia. 13: 177. DOI: 10.1016/J.Jalz.2017.07.022  0.425
2017 Westwood S, Hye A, Lleó A, Nevado-Holgado AJ, Baird AL, Wallin A, Leslie A, Jimenez B, Liu BY, Legido-Quigley C, Dima D, Ruvolo D, Holmes E, D'Hondt E, Westman E, ... Barkhof F, et al. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION Alzheimer's & Dementia. 13: P174-P175. DOI: 10.1016/J.Jalz.2017.07.016  0.45
2017 Haan Jd, Kreeke Avd, Verbraak F, Nadyarnykh O, Teunissen CE, Barkhof F, Berckel BNMv, Scheltens P, Bouwman FH, Boer Jd. Amyloid Visualization In The Retina Of Alzheimer’S Disease Patients With Curcumin Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.897  0.41
2017 Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird AL, Legido-Quigley C, Bertram L, Barkhof F, et al. European Medical Information Framework For Alzheimer’S Disease (Emif-Ad): The Biomarker Discovery Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.864  0.401
2017 Ingala S, Martens RM, Bechten A, van Schijndel RA, Machado V, de Jong MC, Sanchez E, Arrighi M, Purcell DD, Brashear R, Wattjes MP, Barkhof F. [P1-400]: USING SUBTRACTION MRI TO IMPROVE THE DETECTION OF AMYLOID-RELATED IMAGING ABNORMALITIES WITH EDEMA OR EFFUSION (ARIA-E) IN PATIENTS AFFECTED BY ALZHEIMER's DISEASE RECEIVING IMMUNOTHERAPY: AN INTER-OBSERVER STUDY Alzheimer's & Dementia. 13: P425-P427. DOI: 10.1016/J.Jalz.2017.06.416  0.361
2017 Farrar G, Barkhof F, Pla S, Gispert JD, Foley C, Mett A, Ritchie CW, Georges J, Stephens A, Schmidt ME, Van Der Geyten S, Frisoni GB. [P1-395]: AMYPAD: A EUROPEAN PUBLIC-PRIVATE PARTNERSHIP TO INVESTIGATE THE VALUE OF β-AMYLOID BRAIN SCANS AS A DIAGNOSTIC AND THERAPEUTIC MARKER FOR ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P420-P420. DOI: 10.1016/J.Jalz.2017.06.411  0.314
2017 Wottschel V, Wink AM, Tijms BM, Collij L, Kuijer J, van der Flier WM, Scheltens P, Barkhof F. [P1-392]: AUTOMATED SELECTION OF MULTIMODAL MRI BIOMARKERS FOR DIAGNOSIS OF DEMENTIA Alzheimer's & Dementia. 13: P417-P418. DOI: 10.1016/J.Jalz.2017.06.408  0.699
2017 Westwood S, Baird AL, Hye A, Bos I, Vos SJ, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Snowden SG, ... ... Barkhof F, et al. [P1-289]: DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimer's & Dementia. 13: P361-P362. DOI: 10.1016/J.Jalz.2017.06.305  0.432
2017 Bouts MJRJ, Möller C, Hafkemeijer A, Swieten JCv, Dopper EGP, Flier WMvd, Vrenken H, Wink AM, Pijnenburg YAL, Scheltens P, Barkhof F, Grond Jvd, Rooij Md, Rombouts SARB. Mri-Based Classification Accuracy Of Dementia Type Is Determined By Mri Modality Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2404  0.502
2017 Verfaillie SCJ, Slot RER, Dicks E, Prins ND, Overbeek JM, Scheltens P, Barkhof F, Flier WMvd, Tijms BM. Grey Matter Connectivity Is Related To A Steeper Loss Of Memory And Language Functioning Over Time In Patients With Subjective Cognitive Decline Alzheimers & Dementia. 13: 451. DOI: 10.1016/J.Jalz.2017.06.2384  0.44
2017 Kate Mt, Sudre CH, Braber Ad, Konijnenberg E, Cardoso MJ, Scheltens P, Ourselin S, Boomsma DI, Barkhof F, Visser PJ. White Matter Hyperintensities And Vascular Risk Factors In Cognitively Healthy Elderly Monozygotic Twin Pairs Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2338  0.433
2017 Groot C, Weijden CWJvd, Flier WMvd, Loenhoud ACv, Berckel BNMv, Barkhof F, Koene T, Teunissen CE, Scheltens P, Ossenkoppele R. EFFECT OF APOE-ε2 ON REGIONAL GRAY MATTER ATROPHY AND CLINICAL PHENOTYPE IN ALZHEIMER’S DISEASE Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2328  0.452
2017 Braber Ad, Prent N, Kate Mt, Konijnenberg E, Barkhof F, Berckel BNMv, Scheltens P, Boomsma DI, Visser PJ. Early Alterations In Resting-State Functional Connectivity Is Associated With Amyloid Pathology In Cognitively Healthy Elderly Monozygotic Twins Alzheimers & Dementia. 13: 429. DOI: 10.1016/J.Jalz.2017.06.2326  0.449
2017 Leijenaar JF, Pelkmans W, Rozemuller A, Bouwman FH, Flier WMvd, Scheltens P, Barkhof F, Prins ND. Clinical And Radiological Findings In Patients With Pathologically Confirmed Caa Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1639  0.431
2017 Lotjonen J, Koikkalainen J, Meester HFR, Flier WMvd, Scheltens P, Barkhof F, Erkinjuntti T. Computed Rating Scales For Cognitive Disorders From Mri Alzheimers & Dementia. 13: 1108. DOI: 10.1016/J.Jalz.2017.06.1602  0.418
2017 Dicks E, Tijms BM, Gouw AA, Benedictus MR, Barkhof F, Scheltens P, Flier WMvd. Grey Matter Connectivity Is Associated With The Rate Of Cognitive Decline In Mild Cognitive Impairment Alzheimers & Dementia. 13: 69. DOI: 10.1016/J.Jalz.2017.06.1591  0.44
2017 Gispert JD, Foley C, Lammertsma AA, van Berckel BN, Yaqub MM, Cardoso MJ, Markiewicz P, Modat M, Buckley CJ, Mett A, Bullich S, Banton N, Grecci E, Hall J, Hill DL, ... ... Barkhof F, et al. [P2-418]: METHODOLOGICAL AND LOGISTIC STRATEGIES FOR A LARGE MULTI-CENTER β-AMYLOID PET EUROPEAN PROJECT: AMYLOID IMAGING TO PREVENT ALZHEIMER's DISEASE (AMYPAD) Alzheimer's & Dementia. 13: P794-P794. DOI: 10.1016/J.Jalz.2017.06.1074  0.313
2017 Kate Mt, Tijms BM, Konijnenberg E, Braber Ad, Boomsma DI, Scheltens P, Barkhof F, Visser PJ. Correlation Of Grey Matter Network Measures In Cognitively Healthy Elderly Monozygotic Twin Pairs Alzheimers & Dementia. 13: 783. DOI: 10.1016/J.Jalz.2017.06.1054  0.44
2016 Scheltens NME, Kuyper IS, Boellaard R, Barkhof F, Teunissen CE, Broersen LM, Lansbergen MM, van der Flier WM, van Berckel BNM, Scheltens P. Design of the NL-ENIGMA study: Exploring the effect of Souvenaid on cerebral glucose metabolism in early Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 2: 233-240. PMID 29067310 DOI: 10.1016/J.Trci.2016.07.004  0.407
2016 Verfaillie SC, Tijms B, Versteeg A, Benedictus MR, Bouwman FH, Scheltens P, Barkhof F, Vrenken H, van der Flier WM. Thinner temporal and parietal cortex is related to incident clinical progression to dementia in patients with subjective cognitive decline. Alzheimer's & Dementia (Amsterdam, Netherlands). 5: 43-52. PMID 28054027 DOI: 10.1016/J.Dadm.2016.10.007  0.5
2016 Comi G, De Stefano N, Freedman MS, Barkhof F, Uitdehaag BM, de Vos M, Marhardt K, Chen L, Issard D, Kappos L. Subcutaneous interferon β-1a in the treatment of clinically isolated syndromes: 3-year and 5-year results of the phase III dosing frequency-blind multicentre REFLEXION study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28039317 DOI: 10.1136/Jnnp-2016-314843  0.302
2016 Hulst HE, Goldschmidt T, Nitsche MA, de Wit SJ, van den Heuvel OA, Barkhof F, Paulus W, van der Werf YD, Geurts JJ. rTMS affects working memory performance, brain activation and functional connectivity in patients with multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27974394 DOI: 10.1136/Jnnp-2016-314224  0.315
2016 Jokinen H, Melkas S, Madureira S, Verdelho A, Ferro JM, Fazekas F, Schmidt R, Scheltens P, Barkhof F, Wardlaw JM, Inzitari D, Pantoni L, Erkinjuntti T. Cognitive reserve moderates long-term cognitive and functional outcome in cerebral small vessel disease. Journal of Neurology, Neurosurgery, and Psychiatry. 87: 1296-1302. PMID 27951523 DOI: 10.1136/Jnnp-2016-313914  0.461
2016 Vijverberg EG, Tijms BM, Dopp J, Hong YJ, Teunissen CE, Barkhof F, Scheltens P, Pijnenburg YA. Gray matter network differences between behavioral variant frontotemporal dementia and Alzheimer's disease. Neurobiology of Aging. 50: 77-86. PMID 27940352 DOI: 10.1016/J.Neurobiolaging.2016.11.005  0.371
2016 Louwersheimer E, Cohn-Hokke PE, Pijnenburg YA, Weiss MM, Sistermans EA, Rozemuller AJ, Hulsman M, van Swieten JC, van Duijn CM, Barkhof F, Koene T, Scheltens P, Van der Flier WM, Holstege H. Rare Genetic Variant in SORL1 May Increase Penetrance of Alzheimer's Disease in a Family with Several Generations of APOE-ɛ4 Homozygosity. Journal of Alzheimer's Disease : Jad. PMID 27911290 DOI: 10.3233/Jad-160091  0.41
2016 Haller S, Zaharchuk G, Thomas DL, Lovblad KO, Barkhof F, Golay X. Arterial Spin Labeling Perfusion of the Brain: Emerging Clinical Applications. Radiology. 281: 337-356. PMID 27755938 DOI: 10.1148/Radiol.2016150789  0.343
2016 Leeuwis AE, Benedictus MR, Kuijer JP, Binnewijzend MA, Hooghiemstra AM, Verfaillie SC, Koene T, Scheltens P, Barkhof F, Prins ND, van der Flier WM. Lower cerebral blood flow is associated with impairment in multiple cognitive domains in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27693109 DOI: 10.1016/J.Jalz.2016.08.013  0.472
2016 Freeze WM, Jacobs HI, Gronenschild EH, Jansen JF, Burgmans S, Aalten P, Clerx L, Vos SJ, van Buchem MA, Barkhof F, van der Flier WM, Verbeek MM, Rikkert MO, Backes WH, Verhey FR, et al. White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-β. Journal of Alzheimer's Disease : Jad. PMID 27662299 DOI: 10.3233/Jad-160474  0.391
2016 Hafkemeijer A, Möller C, Dopper EG, Jiskoot LC, van den Berg-Huysmans AA, van Swieten JC, van der Flier WM, Vrenken H, Pijnenburg YA, Barkhof F, Scheltens P, van der Grond J, Rombouts SA. A Longitudinal Study on Resting State Functional Connectivity in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27662284 DOI: 10.3233/Jad-150695  0.488
2016 Wijburg MT, Witte BI, Vennegoor A, Roosendaal SD, Sanchez E, Liu Y, Martins Jarnalo CO, Uitdehaag BM, Barkhof F, Killestein J, Wattjes MP. MRI criteria differentiating asymptomatic PML from new MS lesions during natalizumab pharmacovigilance. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27530808 DOI: 10.1136/Jnnp-2016-313772  0.394
2016 Verburg N, Pouwels PJ, Boellaard R, Barkhof F, Hoekstra OS, Reijneveld JC, Vandertop WP, Wesseling P, de Witt Hamer PC. Accurate Delineation of Glioma Infiltration by Advanced PET/MR Neuro-Imaging (FRONTIER Study): A Diagnostic Study Protocol. Neurosurgery. PMID 27479710 DOI: 10.1227/Neu.0000000000001355  0.33
2016 Steenweg ME, Wolf NI, van Wieringen WN, Barkhof F, van der Knaap MS, Pouwels PJ. Quantitative MRI in hypomyelinating disorders: Correlation with motor handicap. Neurology. PMID 27440150 DOI: 10.1212/Wnl.0000000000003000  0.476
2016 Sormani MP, Kappos L, Radue EW, Cohen J, Barkhof F, Sprenger T, Piani Meier D, Häring D, Tomic D, De Stefano N. Defining brain volume cutoffs to identify clinically relevant atrophy in RRMS. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27411701 DOI: 10.1177/1352458516659550  0.359
2016 Shu N, Duan Y, Xia M, Schoonheim MM, Huang J, Ren Z, Sun Z, Ye J, Dong H, Shi FD, Barkhof F, Li K, Liu Y. Disrupted topological organization of structural and functional brain connectomes in clinically isolated syndrome and multiple sclerosis. Scientific Reports. 6: 29383. PMID 27403924 DOI: 10.1038/Srep29383  0.376
2016 Collij LE, Heeman F, Kuijer JP, Ossenkoppele R, Benedictus MR, Möller C, Verfaillie SC, Sanz-Arigita EJ, van Berckel BN, van der Flier WM, Scheltens P, Barkhof F, Wink AM. Application of Machine Learning to Arterial Spin Labeling in Mild Cognitive Impairment and Alzheimer Disease. Radiology. 152703. PMID 27383395 DOI: 10.1148/Radiol.2016152703  0.686
2016 Vijverberg EG, Wattjes MP, Dols A, Krudop WA, Möller C, Peters A, Kerssens CJ, Gossink F, Prins ND, Stek ML, Scheltens P, van Berckel BN, Barkhof F, Pijnenburg YA. Diagnostic Accuracy of MRI and Additional [18F]FDG-PET for Behavioral Variant Frontotemporal Dementia in Patients with Late Onset Behavioral Changes. Journal of Alzheimer's Disease : Jad. PMID 27372646 DOI: 10.3233/Jad-160285  0.409
2016 Chételat G, Ossenkoppele R, Villemagne VL, Perrotin A, Landeau B, Mézenge F, Jagust WJ, Dore V, Miller BL, Egret S, Seeley WW, van der Flier WM, La Joie R, Ames D, van Berckel BN, ... ... Barkhof F, et al. Atrophy, hypometabolism and clinical trajectories in patients with amyloid-negative Alzheimer's disease. Brain : a Journal of Neurology. PMID 27357349 DOI: 10.1093/Brain/Aww159  0.488
2016 Barkhof F. Brain atrophy measurements should be used to guide therapy monitoring in MS - NO. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27335096 DOI: 10.1177/1352458516649452  0.312
2016 Benedictus MR, Leeuwis AE, Binnewijzend MA, Kuijer JP, Scheltens P, Barkhof F, van der Flier WM, Prins ND. Lower cerebral blood flow is associated with faster cognitive decline in Alzheimer's disease. European Radiology. PMID 27334014 DOI: 10.1007/S00330-016-4450-Z  0.468
2016 Cohn-Hokke PE, Holstege H, Weiss MM, van der Flier WM, Barkhof F, Sistermans EA, Pijnenburg YA, van Swieten JC, Meijers-Heijboer H, Scheltens P. A novel CCM2 variant in a family with non-progressive cognitive complaints and cerebral microbleeds. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27277535 DOI: 10.1002/Ajmg.B.32468  0.465
2016 Cover KS, van Schijndel RA, Versteeg A, Leung KK, Mulder ER, Jong RA, Visser PJ, Redolfi A, Revillard J, Grenier B, Manset D, Damangir S, Bosco P, Vrenken H, van Dijk BW, ... ... Barkhof F, et al. Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease. Psychiatry Research. 252: 26-35. PMID 27179313 DOI: 10.1016/J.Pscychresns.2016.04.006  0.333
2016 Vijverberg EG, Dols A, Krudop WA, Peters A, Kerssens CJ, van Berckel BN, Wattjes MP, Barkhof F, Gossink F, Prins ND, Stek ML, Scheltens P, Pijnenburg YA. Diagnostic Accuracy of the Frontotemporal Dementia Consensus Criteria in the Late-Onset Frontal Lobe Syndrome. Dementia and Geriatric Cognitive Disorders. 41: 210-9. PMID 27160162 DOI: 10.1159/000444849  0.431
2016 Koikkalainen J, Rhodius-Meester H, Tolonen A, Barkhof F, Tijms B, Lemstra AW, Tong T, Guerrero R, Schuh A, Ledig C, Rueckert D, Soininen H, Remes AM, Waldemar G, Hasselbalch S, et al. Differential diagnosis of neurodegenerative diseases using structural MRI data. Neuroimage. Clinical. 11: 435-49. PMID 27104138 DOI: 10.1016/J.Nicl.2016.02.019  0.403
2016 Hagens M, van Berckel B, Barkhof F. Novel MRI and PET markers of neuroinflammation in multiple sclerosis. Current Opinion in Neurology. PMID 27058220 DOI: 10.1097/Wco.0000000000000326  0.388
2016 Brueggen K, Grothe MJ, Dyrba M, Fellgiebel A, Fischer F, Filippi M, Agosta F, Nestor P, Meisenzahl E, Blautzik J, Frölich L, Hausner L, Bokde AL, Frisoni G, Pievani M, ... ... Barkhof F, et al. The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment. Neuroimage. PMID 27046114 DOI: 10.1016/J.Neuroimage.2016.03.067  0.439
2016 Wiebenga OT, Schoonheim MM, Hulst HE, Nagtegaal GJ, Strijbis EM, Steenwijk MD, Polman CH, Pouwels PJ, Barkhof F, Geurts JJ. White Matter Diffusion Changes during the First Year of Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis. Ajnr. American Journal of Neuroradiology. PMID 26965463 DOI: 10.3174/Ajnr.A4690  0.637
2016 Kilsdonk ID, Jonkman LE, Klaver R, van Veluw SJ, Zwanenburg JJ, Kuijer JP, Pouwels PJ, Twisk JW, Wattjes MP, Luijten PR, Barkhof F, Geurts JJ. Increased cortical grey matter lesion detection in multiple sclerosis with 7 T MRI: a post-mortem verification study. Brain : a Journal of Neurology. PMID 26956422 DOI: 10.1093/Brain/Aww037  0.547
2016 Popescu V, Klaver R, Versteeg A, Voorn P, Twisk JW, Barkhof F, Geurts JJ, Vrenken H. Postmortem validation of MRI cortical volume measurements in MS. Human Brain Mapping. PMID 26945922 DOI: 10.1002/Hbm.23168  0.555
2016 Harper L, Fumagalli GG, Barkhof F, Scheltens P, O'Brien JT, Bouwman F, Burton EJ, Rohrer JD, Fox NC, Ridgway GR, Schott JM. MRI visual rating scales in the diagnosis of dementia: evaluation in 184 post-mortem confirmed cases. Brain : a Journal of Neurology. PMID 26936938 DOI: 10.1093/Brain/Aww005  0.478
2016 Preziosa P, Rocca MA, Pagani E, Stromillo ML, Enzinger C, Gallo A, Hulst HE, Atzori M, Pareto D, Riccitelli GC, Copetti M, De Stefano N, Fazekas F, Bisecco A, Barkhof F, et al. Structural MRI correlates of cognitive impairment in patients with multiple sclerosis: A Multicenter Study. Human Brain Mapping. PMID 26833969 DOI: 10.1002/Hbm.23125  0.432
2016 Möller C, Hafkemeijer A, Pijnenburg YA, Rombouts SA, van der Grond J, Dopper E, van Swieten J, Versteeg A, Steenwijk MD, Barkhof F, Scheltens P, Vrenken H, van der Flier WM. Different patterns of cortical gray matter loss over time in behavioral variant frontotemporal dementia and Alzheimer's disease. Neurobiology of Aging. 38: 21-31. PMID 26827640 DOI: 10.1016/J.Neurobiolaging.2015.10.020  0.494
2016 Ten Kate M, Sanz-Arigita EJ, Tijms BM, Wink AM, Clerigue M, Garcia-Sebastian M, Izagirre A, Ecay-Torres M, Estanga A, Villanua J, Vrenken H, Visser PJ, Martinez-Lage P, Barkhof F. Impact of APOE-ɛ4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults. Neurobiology of Aging. 38: 14-20. PMID 26827639 DOI: 10.1016/J.Jalz.2015.06.130  0.655
2016 Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, ... Barkhof F, et al. MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines. The Lancet. Neurology. PMID 26822746 DOI: 10.1016/S1474-4422(15)00393-2  0.405
2016 Zhang Y, Jonkman L, Klauser A, Barkhof F, Yong VW, Metz LM, Geurts JJ. Multi-scale MRI spectrum detects differences in myelin integrity between MS lesion types. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26754802 DOI: 10.1177/1352458515624771  0.576
2016 Popescu V, Schoonheim MM, Versteeg A, Chaturvedi N, Jonker M, Xavier de Menezes R, Gallindo Garre F, Uitdehaag BM, Barkhof F, Vrenken H. Grey Matter Atrophy in Multiple Sclerosis: Clinical Interpretation Depends on Choice of Analysis Method. Plos One. 11: e0143942. PMID 26745873 DOI: 10.1371/Journal.Pone.0143942  0.385
2016 Prins ND, Bergeron D, Groot C, Loenhoud ACv, Laforce R, Berckel BNMv, Barkhof F, Flier WMvd, Scheltens P, Ossenkoppele R. Impact Of Co-Morbid Amyloid Pathology On Clinical Phenotype Of Patients With Vascular Cognitive Disorders Alzheimers & Dementia. 12: 472. DOI: 10.1016/J.Jalz.2016.06.926  0.45
2016 Maurik ISv, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Wattjes M, Berkhof J, Flier WMvd. Personalized Risk Estimates For Mci Patients: Taking Biomarkers Into The Clinic Alzheimers & Dementia. 12: 393. DOI: 10.1016/J.Jalz.2016.06.742  0.395
2016 Tijms BM, Kate Mt, Gouw AA, Teunissen CE, Barkhof F, Scheltens P, Flier WMvd. Grey Matter Connectivity Is Associated With Time To Clinical Progression In Mild Cognitive Impairment, Independent Of Amyloid Status Alzheimers & Dementia. 12: 303. DOI: 10.1016/J.Jalz.2016.06.549  0.48
2016 van Loenhoud AC, Wink AM, Groot C, Verfaillie SC, Barkhof F, van Berckel BN, Scheltens P, van der Flier WM, Ossenkoppele R. P4-191: A Novel Neuroimaging Approach to Capture Cognitive Reserve Alzheimer's & Dementia. 12: P1095-P1096. DOI: 10.1016/J.Jalz.2016.06.2283  0.654
2016 Verfaillie SCJ, Slot RER, Tijms BM, Bouwman FH, Benedictus M, Overbeek J, Koene T, Vrenken H, Scheltens P, Barkhof F, Flier WMvd. Thinner Cortical Thickness In Patients With Subjective Cognitive Decline Is Related To Poor Memory Performance And Faster Decline Of Executive Function Alzheimers & Dementia. 12: 774. DOI: 10.1016/J.Jalz.2016.06.184  0.438
2016 Scheltens NM, Tijms BM, Koene T, Barkhof F, Teunissen CE, Wolfsgruber S, Wagner M, Kornhuber J, Peters O, Cohn-Sheehy B, Rabinovici GD, Miller B, Kramer J, Scheltens P, van der Flier WM. P3-144: Cognitive Subtypes Identified Using Nonnegative Matrix Factorisation in Four Large Alzheimer's Disease Dementia Cohorts Alzheimer's & Dementia. 12: P873-P874. DOI: 10.1016/J.Jalz.2016.06.1804  0.471
2016 Kate Mt, Visser PJ, Flier WMvd, Scheltens P, Barkhof F, Tijms BM. Atrophy Patterns Predicting Cognitive Decline In Non-Demented Subjects Are Independent Of Amyloid Pathology Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.177  0.446
2016 Leijenaar JF, Maurik ISv, Kuijer J, Flier WMvd, Scheltens P, Barkhof F, Prins ND. Cerebral Blood Flow Measured With Phase-Contrast Mri In Ad, Mci And Controls Alzheimers & Dementia. 12: 706. DOI: 10.1016/J.Jalz.2016.06.1389  0.425
2016 Bron EE, Young AL, Oxtoby NP, Smits M, Swieten JCv, Wink AM, Flier WMvd, Barkhof F, Golay X, Niessen WJ, Klein S, Alexander DC. Cross-Sectional Modeling Of Regional Perfusion And Gray Matter Volume In Alzheimer'S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.136  0.302
2016 Groot C, van Loenhoud AC, van Berckel BN, Barkhof F, Koene T, Teunissen CE, Scheltens P, van der Flier WM, Ossenkoppele R. IC-P-103: Active and Passive Reserve Differentially Mitigate Cognitive Symptoms in Demented and Non-Demented Stages of Alzheimer’s Disease Alzheimer's & Dementia. 12: P78-P79. DOI: 10.1016/J.Jalz.2016.06.133  0.415
2016 Tijms BM, Kate Mt, Verfaillie SCJ, Gouw AA, Teunissen CE, Barkhof F, Scheltens P, Flier WMvd. Grey Matter Connectivity Is Associated With Clinical Progression In Non-Demented, Amyloid Positive Patients Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.072  0.459
2016 Braber Ad, Konijnenberg E, Kate Mt, Tijms BM, Barkhof F, Boomsma DI, Scheltens P, Visser PJ. Correlation of cortical thickness in cognitively healthy elderly monozygotic twin pairs Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.069  0.432
2015 Liu Y, Dai Z, Duan Y, Huang J, Ren Z, Liu Z, Dong H, Shu N, Vrenken H, Wattjes MP, Barkhof F, He Y, Li K. Whole brain functional connectivity in clinically isolated syndrome without conventional brain MRI lesions. European Radiology. PMID 26714968 DOI: 10.1007/S00330-015-4147-8  0.379
2015 van Duinkerken E, Ijzerman RG, Klein M, Moll AC, Snoek FJ, Scheltens P, Pouwels PJ, Barkhof F, Diamant M, Tijms BM. Disrupted subject-specific gray matter network properties and cognitive dysfunction in type 1 diabetes patients with and without proliferative retinopathy. Human Brain Mapping. PMID 26700243 DOI: 10.1002/Hbm.23096  0.468
2015 Jokinen H, Gonçalves N, Vigário R, Lipsanen J, Fazekas F, Schmidt R, Barkhof F, Madureira S, Verdelho A, Inzitari D, Pantoni L, Erkinjuntti T. Early-Stage White Matter Lesions Detected by Multispectral MRI Segmentation Predict Progressive Cognitive Decline. Frontiers in Neuroscience. 9: 455. PMID 26696814 DOI: 10.3389/Fnins.2015.00455  0.423
2015 Jonkman LE, Fleysher L, Steenwijk MD, Koeleman JA, de Snoo TP, Barkhof F, Inglese M, Geurts JJ. Ultra-high field MTR and qR2* differentiates subpial cortical lesions from normal-appearing gray matter in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26672996 DOI: 10.1177/1352458515620499  0.575
2015 Hafkemeijer A, Möller C, Dopper EG, Jiskoot LC, van den Berg-Huysmans AA, van Swieten JC, van der Flier WM, Vrenken H, Pijnenburg YA, Barkhof F, Scheltens P, van der Grond J, Rombouts SA. Differences in structural covariance brain networks between behavioral variant frontotemporal dementia and Alzheimer's disease. Human Brain Mapping. PMID 26660857 DOI: 10.1002/Hbm.23081  0.48
2015 Liu Y, Lukas C, Steenwijk M, Daams M, Versteeg A, Duan Y, Li K, Weiler F, Hahn HK, Wattjes MP, Barkhof F, Vrenken H. Multicenter Validation of Mean Upper Cervical Cord Area Measurements from Head 3D T1-Weighted MR Imaging in Patients with Multiple Sclerosis. Ajnr. American Journal of Neuroradiology. PMID 26659338 DOI: 10.3174/Ajnr.A4635  0.326
2015 Möller C, Pijnenburg YA, van der Flier WM, Versteeg A, Tijms B, de Munck JC, Hafkemeijer A, Rombouts SA, van der Grond J, van Swieten J, Dopper E, Scheltens P, Barkhof F, Vrenken H, Wink AM. Alzheimer Disease and Behavioral Variant Frontotemporal Dementia: Automatic Classification Based on Cortical Atrophy for Single-Subject Diagnosis. Radiology. 150220. PMID 26653846 DOI: 10.1148/Radiol.2015150220  0.694
2015 Steenwijk MD, Geurts JJ, Daams M, Tijms BM, Wink AM, Balk LJ, Tewarie PK, Uitdehaag BM, Barkhof F, Vrenken H, Pouwels PJ. Cortical atrophy patterns in multiple sclerosis are non-random and clinically relevant. Brain : a Journal of Neurology. PMID 26637488 DOI: 10.1093/Brain/Awv337  0.729
2015 Möller C, Hafkemeijer A, Pijnenburg YA, Rombouts SA, van der Grond J, Dopper E, van Swieten J, Versteeg A, Pouwels PJ, Barkhof F, Scheltens P, Vrenken H, van der Flier WM. Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study. Neuroimage. Clinical. 9: 418-29. PMID 26594624 DOI: 10.1016/J.Nicl.2015.08.022  0.488
2015 Rhodius-Meester HF, Koikkalainen J, Mattila J, Teunissen CE, Barkhof F, Lemstra AW, Scheltens P, Lötjönen J, van der Flier WM. Integrating Biomarkers for Underlying Alzheimer's Disease in Mild Cognitive Impairment in Daily Practice: Comparison of a Clinical Decision Support System with Individual Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 26577521 DOI: 10.3233/Jad-150548  0.491
2015 Steenwijk MD, Vrenken H, Jonkman LE, Daams M, Geurts JJ, Barkhof F, Pouwels PJ. High-resolution T1-relaxation time mapping displays subtle, clinically relevant, gray matter damage in long-standing multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26564997 DOI: 10.1177/1352458515615953  0.575
2015 Wattjes MP, Wijburg MT, Vennegoor A, Witte BI, Roosendaal SD, Sanchez E, Liu Y, Martins Jarnalo CO, Richert ND, Uitdehaag BM, Barkhof F, Killestein J. Diagnostic performance of brain MRI in pharmacovigilance of natalizumab-treated MS patients. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26564995 DOI: 10.1177/1352458515615225  0.408
2015 Tijms BM, Kate MT, Wink AM, Visser PJ, Ecay M, Clerigue M, Estanga A, Garcia Sebastian M, Izagirre A, Villanua J, Martinez Lage P, van der Flier WM, Scheltens P, Sanz Arigita E, Barkhof F. Gray matter network disruptions and amyloid beta in cognitively normal adults. Neurobiology of Aging. PMID 26559882 DOI: 10.1016/J.Neurobiolaging.2015.10.015  0.702
2015 Enzinger C, Barkhof F, Ciccarelli O, Filippi M, Kappos L, Rocca MA, Ropele S, Rovira À, Schneider T, de Stefano N, Vrenken H, Wheeler-Kingshott C, Wuerfel J, Fazekas F. Nonconventional MRI and microstructural cerebral changes in multiple sclerosis. Nature Reviews. Neurology. PMID 26526531 DOI: 10.1038/Nrneurol.2015.194  0.405
2015 Gardeniers M, Wattjes MP, Meulen EF, Barkhof F, Bakker J. [Diagnostic imaging in dementia: use of imaging modalities in Dutch memory clinics]. Tijdschrift Voor Gerontologie En Geriatrie. PMID 26525706 DOI: 10.1007/S12439-015-0154-0  0.316
2015 Krudop WA, Dols A, Kerssens CJ, Prins ND, Möller C, Schouws S, Barkhof F, van Berckel BN, Teunissen CE, van der Flier WM, Scheltens P, Sikkes SA, Stek ML, Pijnenburg YA. Impact of Imaging and Cerebrospinal Fluid Biomarkers on Behavioral Variant Frontotemporal Dementia Diagnosis within a Late-Onset Frontal Lobe Syndrome Cohort. Dementia and Geriatric Cognitive Disorders. 41: 16-26. PMID 26473985 DOI: 10.1159/000441023  0.453
2015 Cohen J, Belova A, Selmaj K, Wolf C, Sormani MP, Oberyé J, van den Tweel E, Mulder R, Koper N, Voortman G, Barkhof F. Equivalence of Generic Glatiramer Acetate in Multiple Sclerosis: A Randomized Clinical Trial. Jama Neurology. 1-9. PMID 26458034 DOI: 10.1001/Jamaneurol.2015.2154  0.307
2015 Munger KL, Fitzgerald KC, Freedman MS, Hartung HP, Miller DH, Montalbán X, Edan G, Barkhof F, Suarez G, Radue EW, Sandbrink R, Kappos L, Pohl C, Ascherio A. No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT. Neurology. 85: 1694-701. PMID 26453645 DOI: 10.1212/Wnl.0000000000002099  0.323
2015 Hafkemeijer A, Möller C, Dopper EG, Jiskoot LC, Schouten TM, van Swieten JC, van der Flier WM, Vrenken H, Pijnenburg YA, Barkhof F, Scheltens P, van der Grond J, Rombouts SA. Resting state functional connectivity differences between behavioral variant frontotemporal dementia and Alzheimer's disease. Frontiers in Human Neuroscience. 9: 474. PMID 26441584 DOI: 10.3389/Fnhum.2015.00474  0.475
2015 Tillema JM, Hulst HE, Rocca MA, Vrenken H, Steenwijk MD, Damjanovic D, Enzinger C, Ropele S, Tedeschi G, Gallo A, Ciccarelli O, Rovira A, Montalban X, de Stefano N, Stromillo ML, ... ... Barkhof F, et al. Regional cortical thinning in multiple sclerosis and its relation with cognitive impairment: A multicenter study. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26432859 DOI: 10.1177/1352458515607650  0.358
2015 Liu Y, Fu Y, Schoonheim MM, Zhang N, Fan M, Su L, Shen Y, Yan Y, Yang L, Wang Q, Zhang N, Yu C, Barkhof F, Shi FD. Structural MRI substrates of cognitive impairment in neuromyelitis optica. Neurology. PMID 26423432 DOI: 10.1212/Wnl.0000000000002067  0.369
2015 Adriaanse SM, Wink AM, Tijms BM, Ossenkoppele R, Verfaillie S, Lammertsma AA, Boellaard R, Scheltens P, van Berckel BN, Barkhof F. The association of glucose metabolism and eigenvector centrality in Alzheimer's disease. Brain Connectivity. PMID 26414628 DOI: 10.1089/Brain.2014.0320  0.667
2015 Duits FH, Hernandez-Guillamon M, Montaner J, Goos JD, Montañola A, Wattjes MP, Barkhof F, Scheltens P, Teunissen CE, van der Flier WM. Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds. Journal of Alzheimer's Disease : Jad. PMID 26402072 DOI: 10.3233/Jad-143186  0.412
2015 Brueggen K, Dyrba M, Barkhof F, Hausner L, Filippi M, Nestor PJ, Hauenstein K, Klöppel S, Grothe MJ, Kasper E, Teipel SJ. Basal Forebrain and Hippocampus as Predictors of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment - A Multicenter DTI and Volumetry Study. Journal of Alzheimer's Disease : Jad. 48: 197-204. PMID 26401940 DOI: 10.1016/J.Jalz.2015.06.127  0.416
2015 Tillema JM, Derks MG, Pouwels PJ, de Graaf P, van Rappard DF, Barkhof F, Steenweg ME, van der Knaap MS, Wolf NI. Volumetric MRI data correlate to disease severity in metachromatic leukodystrophy. Annals of Clinical and Translational Neurology. 2: 932-40. PMID 26401514 DOI: 10.1002/Acn3.232  0.564
2015 Wattjes MP, Wijburg MT, Vennegoor A, Witte BI, de Vos M, Richert ND, Uitdehaag BM, Barkhof F, Killestein J. MRI characteristics of early PML-IRIS after natalizumab treatment in patients with MS. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26369555 DOI: 10.1136/Jnnp-2015-311411  0.377
2015 Wattjes MP, Rovira À, Miller D, Yousry TA, Sormani MP, de Stefano N, Tintoré M, Auger C, Tur C, Filippi M, Rocca MA, Fazekas F, Kappos L, Polman C, Barkhof F, et al. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-establishing disease prognosis and monitoring patients. Nature Reviews. Neurology. PMID 26369511 DOI: 10.1038/Nrneurol.2015.157  0.577
2015 Ossenkoppele R, Cohn-Sheehy BI, La Joie R, Vogel JW, Möller C, Lehmann M, van Berckel BN, Seeley WW, Pijnenburg YA, Gorno-Tempini ML, Kramer JH, Barkhof F, Rosen HJ, van der Flier WM, Jagust WJ, et al. Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease. Human Brain Mapping. PMID 26260856 DOI: 10.1002/Hbm.22927  0.49
2015 Daams M, Steenwijk MD, Schoonheim MM, Wattjes MP, Balk LJ, Tewarie PK, Killestein J, Uitdehaag BM, Geurts JJ, Barkhof F. Multi-parametric structural magnetic resonance imaging in relation to cognitive dysfunction in long-standing multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26209593 DOI: 10.1177/1352458515596598  0.598
2015 Oudega ML, Dols A, Adelerhof I, Rozing M, Wattjes MP, Comijs HC, Barkhof F, Eikelenboom P, Stek ML, van Exel E. Contribution of white matter hyperintensities, medial temporal lobe atrophy and cortical atrophy on outcome, seven to twelve years after ECT in severely depressed geriatric patients. Journal of Affective Disorders. 185: 144-8. PMID 26186529 DOI: 10.1016/J.Jad.2015.07.011  0.349
2015 Benedictus MR, van Harten AC, Leeuwis AE, Koene T, Scheltens P, Barkhof F, Prins ND, van der Flier WM. White Matter Hyperintensities Relate to Clinical Progression in Subjective Cognitive Decline. Stroke; a Journal of Cerebral Circulation. 46: 2661-4. PMID 26173729 DOI: 10.1161/Strokeaha.115.009475  0.482
2015 Rovira À, Wattjes MP, Tintoré M, Tur C, Yousry TA, Sormani MP, De Stefano N, Filippi M, Auger C, Rocca MA, Barkhof F, Fazekas F, Kappos L, Polman C, Miller D, et al. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-clinical implementation in the diagnostic process. Nature Reviews. Neurology. 11: 471-82. PMID 26149978 DOI: 10.1038/Nrneurol.2015.106  0.568
2015 Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, Joie RL, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, ... ... Barkhof F, et al. The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features. Brain : a Journal of Neurology. 138: 2732-49. PMID 26141491 DOI: 10.1093/Brain/Awv191  0.478
2015 Daams M, Steenwijk MD, Wattjes MP, Geurts JJ, Uitdehaag BM, Tewarie PK, Balk LJ, Pouwels PJ, Killestein J, Barkhof F. Unraveling the neuroimaging predictors for motor dysfunction in long-standing multiple sclerosis. Neurology. 85: 248-55. PMID 26115736 DOI: 10.1212/Wnl.0000000000001756  0.534
2015 Jain S, Sima DM, Ribbens A, Cambron M, Maertens A, Van Hecke W, De Mey J, Barkhof F, Steenwijk MD, Daams M, Maes F, Van Huffel S, Vrenken H, Smeets D. Automatic segmentation and volumetry of multiple sclerosis brain lesions from MR images. Neuroimage. Clinical. 8: 367-75. PMID 26106562 DOI: 10.1016/J.Nicl.2015.05.003  0.393
2015 Liu Y, Duan Y, Huang J, Ren Z, Ye J, Dong H, Shi FD, Barkhof F, Vrenken H, Wattjes MP, Wang J, Li K. Multimodal Quantitative MR Imaging of the Thalamus in Multiple Sclerosis and Neuromyelitis Optica. Radiology. 142786. PMID 26043265 DOI: 10.1148/Radiol.2015142786  0.389
2015 Binnewijzend MA, Benedictus MR, Kuijer JP, van der Flier WM, Teunissen CE, Prins ND, Wattjes MP, van Berckel BN, Scheltens P, Barkhof F. Cerebral perfusion in the predementia stages of Alzheimer's disease. European Radiology. PMID 26040647 DOI: 10.1007/S00330-015-3834-9  0.423
2015 Ossenkoppele R, Mattsson N, Teunissen CE, Barkhof F, Pijnenburg Y, Scheltens P, van der Flier WM, Rabinovici GD. Cerebrospinal fluid biomarkers and cerebral atrophy in distinct clinical variants of probable Alzheimer's disease. Neurobiology of Aging. 36: 2340-7. PMID 25990306 DOI: 10.1016/J.Neurobiolaging.2015.04.011  0.489
2015 Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ, Verfaillie SC, Zwan MD, Adriaanse SM, Lammertsma AA, Barkhof F, Jagust WJ, et al. Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis. Jama. 313: 1939-49. PMID 25988463 DOI: 10.1001/Jama.2015.4669  0.456
2015 Yi HA, Möller C, Dieleman N, Bouwman FH, Barkhof F, Scheltens P, van der Flier WM, Vrenken H. Relation between subcortical grey matter atrophy and conversion from mild cognitive impairment to Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25904810 DOI: 10.1136/Jnnp-2014-309105  0.508
2015 Verfaillie SC, Adriaanse SM, Binnewijzend MA, Benedictus MR, Ossenkoppele R, Wattjes MP, Pijnenburg YA, van der Flier WM, Lammertsma AA, Kuijer JP, Boellaard R, Scheltens P, van Berckel BN, Barkhof F. Cerebral perfusion and glucose metabolism in Alzheimer's disease and frontotemporal dementia: two sides of the same coin? European Radiology. PMID 25899416 DOI: 10.1007/S00330-015-3696-1  0.477
2015 Bisecco A, Rocca MA, Pagani E, Mancini L, Enzinger C, Gallo A, Vrenken H, Stromillo ML, Copetti M, Thomas DL, Fazekas F, Tedeschi G, Barkhof F, Stefano ND, Filippi M, et al. Connectivity-based parcellation of the thalamus in multiple sclerosis and its implications for cognitive impairment: A multicenter study. Human Brain Mapping. 36: 2809-25. PMID 25873194 DOI: 10.1002/Hbm.22809  0.439
2015 Harper L, Barkhof F, Fox NC, Schott JM. Using visual rating to diagnose dementia: a critical evaluation of MRI atrophy scales. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25872513 DOI: 10.1136/Jnnp-2014-310090  0.347
2015 Barkhof F, Geurts JJ. Laminar cortical damage in multiple sclerosis. Brain : a Journal of Neurology. 138: 828-9. PMID 25802316 DOI: 10.1093/Brain/Awv031  0.559
2015 Benedictus MR, Prins ND, Goos JD, Scheltens P, Barkhof F, van der Flier WM. Microbleeds, Mortality, and Stroke in Alzheimer Disease: The MISTRAL Study. Jama Neurology. 72: 539-45. PMID 25798556 DOI: 10.1001/Jamaneurol.2015.14  0.435
2015 Scheltens NM, Galindo-Garre F, Pijnenburg YA, van der Vlies AE, Smits LL, Koene T, Teunissen CE, Barkhof F, Wattjes MP, Scheltens P, van der Flier WM. The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25783437 DOI: 10.1136/Jnnp-2014-309582  0.487
2015 Redolfi A, Manset D, Barkhof F, Wahlund LO, Glatard T, Mangin JF, Frisoni GB. Head-to-head comparison of two popular cortical thickness extraction algorithms: a cross-sectional and longitudinal study. Plos One. 10: e0117692. PMID 25781983 DOI: 10.1371/Journal.Pone.0117692  0.348
2015 Liu Y, Wang J, Daams M, Weiler F, Hahn HK, Duan Y, Huang J, Ren Z, Ye J, Dong H, Vrenken H, Wattjes MP, Shi FD, Li K, Barkhof F. Differential patterns of spinal cord and brain atrophy in NMO and MS. Neurology. 84: 1465-72. PMID 25762714 DOI: 10.1212/Wnl.0000000000001441  0.352
2015 Jonkman LE, Soriano AL, Amor S, Barkhof F, van der Valk P, Vrenken H, Geurts JJ. Can MS lesion stages be distinguished with MRI? A postmortem MRI and histopathology study. Journal of Neurology. 262: 1074-80. PMID 25761376 DOI: 10.1007/S00415-015-7689-4  0.578
2015 Gass A, Rocca MA, Agosta F, Ciccarelli O, Chard D, Valsasina P, Brooks JC, Bischof A, Eisele P, Kappos L, Barkhof F, Filippi M. MRI monitoring of pathological changes in the spinal cord in patients with multiple sclerosis. The Lancet. Neurology. 14: 443-54. PMID 25748099 DOI: 10.1016/S1474-4422(14)70294-7  0.335
2015 Wiebenga OT, Klauser AM, Schoonheim MM, Nagtegaal GJ, Steenwijk MD, van Rossum JA, Polman CH, Barkhof F, Pouwels PJ, Geurts JJ. Enhanced Axonal Metabolism during Early Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis. Ajnr. American Journal of Neuroradiology. 36: 1116-23. PMID 25742985 DOI: 10.3174/Ajnr.A4252  0.652
2015 Hulst HE, Schoonheim MM, Van Geest Q, Uitdehaag BM, Barkhof F, Geurts JJ. Memory impairment in multiple sclerosis: Relevance of hippocampal activation and hippocampal connectivity. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 25680986 DOI: 10.1177/1352458514567727  0.556
2015 Arrighi HM, Barakos J, Barkhof F, Tampieri D, Jack C, Melançon D, Morris K, Ketter N, Liu E, Brashear HR. Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25669746 DOI: 10.1136/Jnnp-2014-309493  0.376
2015 Louwersheimer E, Ramirez A, Cruchaga C, Becker T, Kornhuber J, Peters O, Heilmann S, Wiltfang J, Jessen F, Visser PJ, Scheltens P, Pijnenburg YA, Teunissen CE, Barkhof F, van Swieten JC, et al. The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. Neurobiology of Aging. 36: 1605.e13-20. PMID 25659857 DOI: 10.1016/J.Neurobiolaging.2014.12.007  0.439
2015 Bron EE, Smits M, van der Flier WM, Vrenken H, Barkhof F, Scheltens P, Papma JM, Steketee RM, Méndez Orellana C, Meijboom R, Pinto M, Meireles JR, Garrett C, Bastos-Leite AJ, Abdulkadir A, et al. Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: the CADDementia challenge. Neuroimage. 111: 562-79. PMID 25652394 DOI: 10.1016/J.Neuroimage.2015.01.048  0.439
2015 Prestia A, Caroli A, Wade SK, van der Flier WM, Ossenkoppele R, Van Berckel B, Barkhof F, Teunissen CE, Wall A, Carter SF, Schöll M, Choo IH, Nordberg A, Scheltens P, Frisoni GB. Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25646957 DOI: 10.1016/J.Jalz.2014.12.001  0.487
2015 Dyrba M, Barkhof F, Fellgiebel A, Filippi M, Hausner L, Hauenstein K, Kirste T, Teipel SJ. Predicting Prodromal Alzheimer's Disease in Subjects with Mild Cognitive Impairment Using Machine Learning Classification of Multimodal Multicenter Diffusion-Tensor and Magnetic Resonance Imaging Data. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 25644739 DOI: 10.1111/Jon.12214  0.415
2015 Radue EW, Barkhof F, Kappos L, Sprenger T, Häring DA, de Vera A, von Rosenstiel P, Bright JR, Francis G, Cohen JA. Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. Neurology. 84: 784-93. PMID 25632085 DOI: 10.1212/Wnl.0000000000001281  0.414
2015 Steenwijk MD, Daams M, Pouwels PJ, J Balk L, Tewarie PK, Geurts JJ, Barkhof F, Vrenken H. Unraveling the relationship between regional gray matter atrophy and pathology in connected white matter tracts in long-standing multiple sclerosis. Human Brain Mapping. 36: 1796-807. PMID 25627545 DOI: 10.1002/Hbm.22738  0.586
2015 Schoonheim MM, Hulst HE, Brandt RB, Strik M, Wink AM, Uitdehaag BM, Barkhof F, Geurts JJ. Thalamus structure and function determine severity of cognitive impairment in multiple sclerosis. Neurology. 84: 776-83. PMID 25616483 DOI: 10.1212/Wnl.0000000000001285  0.722
2015 Barkhof F, Reich DS. Can leptomeningeal enhancement be linked to multiple sclerosis? Neurology. 84: 762-3. PMID 25616481 DOI: 10.1212/Wnl.0000000000001292  0.385
2015 Popescu V, Klaver R, Voorn P, Galis-de Graaf Y, Knol D, Twisk J, Versteeg A, Schenk G, Van der Valk P, Barkhof F, De Vries H, Vrenken H, Geurts J. What drives MRI-measured cortical atrophy in multiple sclerosis? Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 25583833 DOI: 10.1177/1352458514562440  0.57
2015 Caroli A, Prestia A, Galluzzi S, Ferrari C, van der Flier WM, Ossenkoppele R, Van Berckel B, Barkhof F, Teunissen C, Wall AE, Carter SF, Schöll M, Choo IH, Grimmer T, Redolfi A, et al. Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression. Neurology. 84: 508-15. PMID 25568301 DOI: 10.1212/Wnl.0000000000001209  0.475
2015 Roosendaal SD, Barkhof F. Imaging phenotypes in multiple sclerosis. Neuroimaging Clinics of North America. 25: 83-96. PMID 25476514 DOI: 10.1016/J.Nic.2014.09.008  0.375
2015 Möller C, Dieleman N, van der Flier WM, Versteeg A, Pijnenburg Y, Scheltens P, Barkhof F, Vrenken H. More atrophy of deep gray matter structures in frontotemporal dementia compared to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 635-47. PMID 25322925 DOI: 10.3233/Jad-141230  0.469
2015 Tewarie P, Schoonheim MM, Schouten DI, Polman CH, Balk LJ, Uitdehaag BM, Geurts JJ, Hillebrand A, Barkhof F, Stam CJ. Functional brain networks: linking thalamic atrophy to clinical disability in multiple sclerosis, a multimodal fMRI and MEG study. Human Brain Mapping. 36: 603-18. PMID 25293505 DOI: 10.1002/Hbm.22650  0.656
2015 Frisoni GB, Jack CR, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, ... ... Barkhof F, et al. The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 111-25. PMID 25267715 DOI: 10.1016/J.Jalz.2014.05.1756  0.391
2015 Haller S, Barkhof F, Wattjes MP, Lalive PH. Transient gadolinium leakage in natalizumab-treated multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 475-6. PMID 25246642 DOI: 10.1136/Jnnp-2014-309069  0.353
2015 Wattjes MP, Vennegoor A, Steenwijk MD, de Vos M, Killestein J, van Oosten BW, Mostert J, Siepman DA, Moll W, van Golde AE, Frequin ST, Richert ND, Barkhof F. MRI pattern in asymptomatic natalizumab-associated PML. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 793-8. PMID 25205744 DOI: 10.1136/Jnnp-2014-308630  0.375
2015 Richiardi J, Monsch AU, Haas T, Barkhof F, Van de Ville D, Radü EW, Kressig RW, Haller S. Altered cerebrovascular reactivity velocity in mild cognitive impairment and Alzheimer's disease. Neurobiology of Aging. 36: 33-41. PMID 25146454 DOI: 10.1016/J.Neurobiolaging.2014.07.020  0.393
2015 van Rooden S, Doan NT, Versluis MJ, Goos JD, Webb AG, Oleksik AM, van der Flier WM, Scheltens P, Barkhof F, Weverling-Rynsburger AW, Blauw GJ, Reiber JH, van Buchem MA, Milles J, van der Grond J. 7T T₂*-weighted magnetic resonance imaging reveals cortical phase differences between early- and late-onset Alzheimer's disease. Neurobiology of Aging. 36: 20-6. PMID 25113794 DOI: 10.1016/J.Neurobiolaging.2014.07.006  0.474
2015 Kilsdonk ID, Steenwijk MD, Pouwels PJ, Zwanenburg JJ, Visser F, Luijten PR, Geurts J, Barkhof F, Wattjes MP. Perivascular spaces in MS patients at 7 Tesla MRI: a marker of neurodegeneration? Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 155-62. PMID 25013150 DOI: 10.1177/1352458514540358  0.566
2015 Balk LJ, Steenwijk MD, Tewarie P, Daams M, Killestein J, Wattjes MP, Vrenken H, Barkhof F, Polman CH, Uitdehaag BM, Petzold A. Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 419-24. PMID 24973342 DOI: 10.1136/Jnnp-2014-308189  0.49
2015 Lukas C, Knol DL, Sombekke MH, Bellenberg B, Hahn HK, Popescu V, Weier K, Radue EW, Gass A, Kappos L, Naegelin Y, Uitdehaag BM, Geurts JJ, Barkhof F, Vrenken H. Cervical spinal cord volume loss is related to clinical disability progression in multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 410-8. PMID 24973341 DOI: 10.1136/Jnnp-2014-308021  0.531
2015 van Straaten EC, den Haan J, de Waal H, van der Flier WM, Barkhof F, Prins ND, Stam CJ. Disturbed phase relations in white matter hyperintensity based vascular dementia: an EEG directed connectivity study. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 126: 497-504. PMID 24969377 DOI: 10.1016/J.Clinph.2014.05.018  0.406
2015 Lalive PH, Bridel C, Ferfoglia RI, Kaiser L, Du Pasquier R, Barkhof F, Haller S. Minimal supportive treatment in natalizumab-related PML in a MS patient. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 354-5. PMID 24957322 DOI: 10.1136/Jnnp-2014-308154  0.329
2015 Silber E, Montalban X, Barkhof F, Khatri B, Hartung H, Ritter S, Meier DP, Tomic D, Kappos L. EFFECT OF FINGOLIMOD VS. IFN-BETA1A ON NO EVIDENCE OF DISEASE ACTIVITY Journal of Neurology, Neurosurgery & Psychiatry. 86: e4.18-e4. DOI: 10.1136/Jnnp-2015-312379.114  0.341
2015 Weiler F, Daams M, Lukas C, Barkhof F, Hahn HK. Highly accurate volumetry of the spinal cord Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9413. DOI: 10.1117/12.2080803  0.304
2015 Rovira À, Wattjes MP, Tintoré M, Tur C, Yousry TA, Sormani MP, de Stefano N, Filippi M, Auger C, Rocca MA, Barkhof F, Fazekas F, Kappos L, Polman C, Miller D, et al. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis—clinical implementation in the diagnostic process Nature Reviews Neurology. DOI: 10.1038/nrneurol.2015.106  0.412
2015 Verfaillie S, Tijms BM, Versteeg A, Bouwman F, Scheltens P, Barkhof F, Vrenken H, Flier WMvd. Reduced cortical thickness in patients with subjective cognitive decline is related to clinical progression Alzheimers & Dementia. 11: 317. DOI: 10.1016/J.Jalz.2015.07.453  0.466
2015 Harper L, Fumagalli GG, Burton EJ, Bouwman F, O'Brien JT, Barkhof F, Scheltens P, Fox NC, Ridgway GR, Schott JM. Visual assessment in postmortem-proven dementias: Clinical expertise versus machine learning Alzheimers & Dementia. 11: 289. DOI: 10.1016/J.Jalz.2015.07.392  0.378
2015 Rhodius-Meester HFM, Koikkalainen J, Mattila J, Lotjonen J, Teunissen CE, Barkhof F, Koene T, Lemstra AW, Scheltens P, Flier WMvd. Assessing underlying Alzheimer's disease pathology in MCI patients from the amsterdam dementia cohort by use of the predictad software tool Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.316  0.47
2015 Kate Mt, Sanz-Arigita E, Tijms BM, Wink AM, Clerigue M, Garcia-Sebastian M, Izagirre A, Ecay M, Estanga A, Villanua JA, Vrenken H, Visser PJ, Martinez-Lage P, Barkhof F. MONDAY, JULY 20, 2015 ORAL SESSIONS O2-09 NEUROIMAGING: IMAGING AND GENETIC RISK FACTORSImpact of ApoE-ɛ4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.177  0.324
2015 Ossenkoppele R, Pijnenburg YA, Perry D, Cohn-Sheehy B, Scheltens NM, Vogel JW, Kramer J, van der Vlies A, La Joie R, Rosen H, van der Flier WM, Grinberg L, Rozemuller A, Huang E, van Berckel BN, ... ... Barkhof F, et al. F2-03-03: Characterization of the behavioral and dysexecutive variants of Alzheimer's disease Alzheimer's & Dementia. 11: P168-P168. DOI: 10.1016/J.Jalz.2015.07.118  0.398
2015 Caroli A, Galluzzi S, Ferrari C, Prestia A, Flier WMvd, Ossenkoppele R, Berckel BNMv, Barkhof F, Teunissen CE, Wall A, Carter SF, Scholl M, Choo IH, Grimmer T, Redolfi A, et al. Alzheimer’s disease core biomarkers and prediction of dementia in MCI: The effect of age at onset Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.064  0.434
2015 Leeuwis A, Benedictus M, Kuijer J, Scheltens P, Barkhof F, Prins N, Flier WMvd. Lower cerebral blood flow is related to more severe cognitive impairment in patients with dementia due to Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.1794  0.479
2015 Benedictus M, Leeuwis A, Kuijer J, Scheltens P, Barkhof F, Flier MWvd, Prins N. Lower cerebral blood flow is associated with cognitive decline in patients with Alzheimer’s disease Alzheimers & Dementia. 11: 806. DOI: 10.1016/J.Jalz.2015.06.1793  0.445
2015 Tijms BM, Kate M, Wink AM, Visser PJ, Ecay M, Estanga A, Clerigue M, Garcia-Sebastian M, Izagirre A, Villanua J, Martinez-Lage P, van der Flier WM, Scheltens P, Sanz-Arigita E, Barkhof F. P3-158: Grey matter network disruptions are related to amyloid beta in cognitively healthy elderly Alzheimer's & Dementia. 11: P689-P689. DOI: 10.1016/j.jalz.2015.06.1529  0.607
2015 Wink AM, Verfaillie S, Adriaanse S, Benedictus M, Kuijer J, de Munck J, Wattjes M, van der Flier WM, Scheltens P, van Berckel BN, Barkhof F. IC-P-124: Classification of resting-state cerebral perfusion maps from patients with Alzheimer's disease and patients with frontotemporal dementia Alzheimer's & Dementia. 11: P85-P85. DOI: 10.1016/J.Jalz.2015.06.146  0.675
2015 Harper L, Burton EJ, Bouwman F, O'Brien JT, Barkhof F, Scheltens P, Fox NC, Ridgway GR, Schott JM. Distinct patterns of atrophy in postmortem confirmed dementias Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.114  0.411
2015 Tijms BM, Wink AM, Kate M, Visser PJ, Ecay M, Izagirre A, Estanga A, Clerigue M, Garcia-Sebastian M, Villanua J, Martinez-Lage P, van der Flier WM, Scheltens P, Sanz-Arigita E, Barkhof F. IC-04-03: Grey matter network disruptions are related to amyloid-beta in cognitively healthy elderly Alzheimer's & Dementia. 11: P11-P11. DOI: 10.1016/J.Jalz.2015.06.017  0.667
2014 Freedman MS, Comi G, De Stefano N, Barkhof F, Polman CH, Uitdehaag BM, Lehr L, Stubinski B, Kappos L. Moving toward earlier treatment of multiple sclerosis: Findings from a decade of clinical trials and implications for clinical practice. Multiple Sclerosis and Related Disorders. 3: 147-55. PMID 25878002 DOI: 10.1016/J.Msard.2013.07.001  0.547
2014 Aalten P, Ramakers IH, Biessels GJ, de Deyn PP, Koek HL, OldeRikkert MG, Oleksik AM, Richard E, Smits LL, van Swieten JC, Teune LK, van der Lugt A, Barkhof F, Teunissen CE, Rozendaal N, et al. The Dutch Parelsnoer Institute - Neurodegenerative diseases; methods, design and baseline results. Bmc Neurology. 14: 254. PMID 25551191 DOI: 10.1186/S12883-014-0254-4  0.39
2014 van Rooden S, Buijs M, van Vliet ME, Versluis MJ, Webb AG, Oleksik AM, van de Wiel L, Middelkoop HA, Blauw GJ, Weverling-Rynsburger AW, Goos JD, van der Flier WM, Koene T, Scheltens P, Barkhof F, et al. Cortical phase changes measured using 7-T MRI in subjects with subjective cognitive impairment, and their association with cognitive function. Nmr in Biomedicine. PMID 25522735 DOI: 10.1002/Nbm.3248  0.48
2014 Prins ND, van der Flier WA, Knol DL, Fox NC, Brashear HR, Nye JS, Barkhof F, Scheltens P. The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial. Alzheimer's Research & Therapy. 6: 47. PMID 25478019 DOI: 10.1186/Alzrt275  0.484
2014 Olde Dubbelink KT, Schoonheim MM, Deijen JB, Twisk JW, Barkhof F, Berendse HW. Functional connectivity and cognitive decline over 3 years in Parkinson disease. Neurology. 83: 2046-53. PMID 25355821 DOI: 10.1212/Wnl.0000000000001020  0.327
2014 Munger KL, Köchert K, Simon KC, Kappos L, Polman CH, Freedman MS, Hartung HP, Miller DH, Montalbán X, Edan G, Barkhof F, Pleimes D, Sandbrink R, Ascherio A, Pohl C. Molecular mechanism underlying the impact of vitamin D on disease activity of MS. Annals of Clinical and Translational Neurology. 1: 605-17. PMID 25285313 DOI: 10.1002/Acn3.91  0.502
2014 Limmroth V, Barkhof F, Desem N, Diamond MP, Tachas G. CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS. Neurology. 83: 1780-8. PMID 25239835 DOI: 10.1212/Wnl.0000000000000926  0.36
2014 Cover KS, van Schijndel RA, Popescu V, van Dijk BW, Redolfi A, Knol DL, Frisoni GB, Barkhof F, Vrenken H. The SIENA/FSL whole brain atrophy algorithm is no more reproducible at 3T than 1.5 T for Alzheimer's disease. Psychiatry Research. 224: 14-21. PMID 25089020 DOI: 10.1016/J.Pscychresns.2014.07.002  0.305
2014 Adriaanse SM, Binnewijzend MA, Ossenkoppele R, Tijms BM, van der Flier WM, Koene T, Smits LL, Wink AM, Scheltens P, van Berckel BN, Barkhof F. Widespread disruption of functional brain organization in early-onset Alzheimer's disease. Plos One. 9: e102995. PMID 25080229 DOI: 10.1371/Journal.Pone.0102995  0.696
2014 Tewarie P, Steenwijk MD, Tijms BM, Daams M, Balk LJ, Stam CJ, Uitdehaag BM, Polman CH, Geurts JJ, Barkhof F, Pouwels PJ, Vrenken H, Hillebrand A. Disruption of structural and functional networks in long-standing multiple sclerosis. Human Brain Mapping. 35: 5946-61. PMID 25053254 DOI: 10.1002/Hbm.22596  0.651
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