David Pitt, MD - Publications

Affiliations: 
Neurology Yale University, New Haven, CT 
Area:
multiple sclerosis

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bagnato F, Sati P, Hemond CC, Elliott C, Gauthier SA, Harrison DM, Mainero C, Oh J, Pitt D, Shinohara RT, Smith SA, Trapp B, Azevedo CJ, Calabresi PA, Henry RG, et al. Imaging chronic active lesions in multiple sclerosis: a consensus statement. Brain : a Journal of Neurology. PMID 38226694 DOI: 10.1093/brain/awae013  0.588
2022 Zinger N, Ponath G, Sweeney E, Nguyen TD, Lo CH, Diaz I, Dimov A, Teng L, Zexter L, Comunale J, Wang Y, Pitt D, Gauthier SA. Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions. Neurology(R) Neuroimmunology & Neuroinflammation. 9. PMID 35046083 DOI: 10.1212/NXI.0000000000001138  0.327
2020 Lucca LE, Lerner BA, Park C, DeBartolo D, Harnett B, Kumar VP, Ponath G, Raddassi K, Huttner A, Hafler DA, Pitt D. Differential expression of the T-cell inhibitor TIGIT in glioblastoma and MS. Neurology(R) Neuroimmunology & Neuroinflammation. 7. PMID 32269065 DOI: 10.1212/Nxi.0000000000000712  0.373
2019 Swanberg KM, Landheer K, Pitt D, Juchem C. Quantifying the Metabolic Signature of Multiple Sclerosis by Proton Magnetic Resonance Spectroscopy: Current Challenges and Future Outlook in the Translation From Proton Signal to Diagnostic Biomarker. Frontiers in Neurology. 10: 1173. PMID 31803127 DOI: 10.3389/Fneur.2019.01173  0.35
2019 Park C, Ponath G, Levine-Ritterman M, Bull E, Swanson EC, De Jager PL, Segal BM, Pitt D. The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions. Acta Neuropathologica Communications. 7: 130. PMID 31405387 DOI: 10.1186/S40478-019-0779-2  0.44
2019 Ramaglia V, Sheikh-Mohamed S, Legg K, Park C, Rojas OL, Zandee S, Fu F, Ornatsky O, Swanson EC, Pitt D, Prat A, McKee TD, Gommerman JL. Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry. Elife. 8. PMID 31368890 DOI: 10.7554/Elife.48051  0.457
2019 Ramaglia V, Sheikh-Mohamed S, Legg K, Park C, Rojas OL, Zandee S, Fu F, Ornatsky O, Swanson EC, Pitt D, Prat A, McKee TD, Gommerman JL. Author response: Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry Elife. DOI: 10.7554/Elife.48051.028  0.368
2018 Kaunzner UW, Kang Y, Zhang S, Morris E, Yao Y, Pandya S, Hurtado Rua SM, Park C, Gillen KM, Nguyen TD, Wang Y, Pitt D, Gauthier SA. Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions. Brain : a Journal of Neurology. PMID 30561514 DOI: 10.1093/Brain/Awy296  0.419
2018 Ponath G, Lincoln MR, Levine-Ritterman M, Park C, Dahlawi S, Mubarak M, Sumida T, Airas L, Zhang S, Isitan C, Nguyen TD, Raine CS, Hafler DA, Pitt D. Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis. Nature Communications. 9: 5337. PMID 30559390 DOI: 10.1038/S41467-018-07785-8  0.551
2018 Pitt D, Ponath G. Astrocytes play a crucial role in the formation and evolution of MS lesions - Yes. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518793026. PMID 30136895 DOI: 10.1177/1352458518793026  0.425
2018 Deh K, Ponath GD, Molvi Z, Parel GT, Gillen KM, Zhang S, Nguyen TD, Spincemaille P, Ma Y, Gupta A, Gauthier SA, Pitt D, Wang Y. Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM. Journal of Magnetic Resonance Imaging : Jmri. PMID 29517817 DOI: 10.1002/Jmri.25997  0.447
2018 Gillen KM, Mubarak M, Nguyen TD, Pitt D. Significance andDetection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions. Frontiers in Immunology. 9: 255. PMID 29515576 DOI: 10.3389/Fimmu.2018.00255  0.468
2018 Ponath G, Park C, Pitt D. The Role of Astrocytes in Multiple Sclerosis. Frontiers in Immunology. 9: 217. PMID 29515568 DOI: 10.3389/Fimmu.2018.00217  0.457
2017 Giles DA, Washnock-Schmid JM, Duncker PC, Dahlawi S, Ponath G, Pitt D, Segal BM. Myeloid cell plasticity in the evolution of central nervous system autoimmunity. Annals of Neurology. PMID 29283442 DOI: 10.1002/Ana.25128  0.397
2016 Ponath G, Ramanan S, Mubarak M, Housley W, Lee S, Sahinkaya FR, Vortmeyer A, Raine CS, Pitt D. Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology. Brain : a Journal of Neurology. PMID 28007993 DOI: 10.1093/Brain/Aww298  0.571
2016 Zhang Y, Gauthier SA, Gupta A, Chen W, Comunale J, Chiang GC, Zhou D, Askin G, Zhu W, Pitt D, Wang Y. Quantitative Susceptibility Mapping and R2* Measured Changes during White Matter Lesion Development in Multiple Sclerosis: Myelin Breakdown, Myelin Debris Degradation and Removal, and Iron Accumulation. Ajnr. American Journal of Neuroradiology. PMID 27256856 DOI: 10.3174/Ajnr.A4825  0.387
2016 Cao Y, Nylander A, Ramanan S, Goods BA, Ponath G, Zabad R, Chiang VL, Vortmeyer AO, Hafler DA, Pitt D. CNS demyelination and enhanced myelin-reactive responses after ipilimumab treatment. Neurology. PMID 26984943 DOI: 10.1212/Wnl.0000000000002594  0.344
2015 Stüber C, Pitt D, Wang Y. Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping. International Journal of Molecular Sciences. 17. PMID 26784172 DOI: 10.3390/Ijms17010100  0.37
2015 Housley WJ, Pitt D, Hafler DA. Biomarkers in multiple sclerosis. Clinical Immunology (Orlando, Fla.). 161: 51-8. PMID 26143623 DOI: 10.1016/J.Clim.2015.06.015  0.376
2015 Orack JC, Deleidi M, Pitt D, Mahajan K, Nicholas JA, Boster AL, Racke MK, Comabella M, Watanabe F, Imitola J. Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration. Stem Cells Translational Medicine. 4: 252-60. PMID 25593207 DOI: 10.5966/Sctm.2014-0133  0.334
2015 Wisnieff C, Ramanan S, Olesik J, Gauthier S, Wang Y, Pitt D. Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron. Magnetic Resonance in Medicine. 74: 564-70. PMID 25137340 DOI: 10.1002/Mrm.25420  0.407
2014 Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, et al. B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes. Science Translational Medicine. 6: 248ra107. PMID 25100741 DOI: 10.1126/Scitranslmed.3008879  0.339
2014 Chen W, Gauthier SA, Gupta A, Comunale J, Liu T, Wang S, Pei M, Pitt D, Wang Y. Quantitative susceptibility mapping of multiple sclerosis lesions at various ages. Radiology. 271: 183-92. PMID 24475808 DOI: 10.1148/Radiol.13130353  0.39
2013 Cox GM, Kithcart AP, Pitt D, Guan Z, Alexander J, Williams JL, Shawler T, Dagia NM, Popovich PG, Satoskar AR, Whitacre CC. Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 191: 1043-54. PMID 23797673 DOI: 10.4049/Jimmunol.1200485  0.414
2013 Mehta V, Pei W, Yang G, Li S, Swamy E, Boster A, Schmalbrock P, Pitt D. Iron is a sensitive biomarker for inflammation in multiple sclerosis lesions. Plos One. 8: e57573. PMID 23516409 DOI: 10.1371/Journal.Pone.0057573  0.419
2013 Boster AL, Nicholas JA, Topalli I, Kisanuki YY, Pei W, Morgan-Followell B, Kirsch CF, Racke MK, Pitt D. Lessons learned from fatal progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with natalizumab. Jama Neurology. 70: 398-402. PMID 23338729 DOI: 10.1001/Jamaneurol.2013.1960  0.309
2012 Bluestein KT, Pitt D, Sammet S, Zachariah CR, Nagaraj U, Knopp MV, Schmalbrock P. Detecting cortical lesions in multiple sclerosis at 7 T using white matter signal attenuation. Magnetic Resonance Imaging. 30: 907-15. PMID 22578928 DOI: 10.1016/J.Mri.2012.03.006  0.408
2012 Bluestein KT, Pitt D, Knopp MV, Schmalbrock P. T1 and proton density at 7 T in patients with multiple sclerosis: an initial study. Magnetic Resonance Imaging. 30: 19-25. PMID 21937183 DOI: 10.1016/J.Mri.2011.07.018  0.401
2011 Boster A, Bartoszek MP, O'Connell C, Pitt D, Racke M. Efficacy, safety, and cost-effectiveness of glatiramer acetate in the treatment of relapsing-remitting multiple sclerosis. Therapeutic Advances in Neurological Disorders. 4: 319-32. PMID 22010043 DOI: 10.1177/1756285611422108  0.303
2011 Schaaf SM, Pitt D, Racke MK. What happens when natalizumab therapy is stopped? Expert Review of Neurotherapeutics. 11: 1247-50. PMID 21864070 DOI: 10.1586/Ern.11.109  0.342
2010 Pitt D, Boster A, Pei W, Wohleb E, Jasne A, Zachariah CR, Rammohan K, Knopp MV, Schmalbrock P. Imaging cortical lesions in multiple sclerosis with ultra-high-field magnetic resonance imaging. Archives of Neurology. 67: 812-8. PMID 20625086 DOI: 10.1001/Archneurol.2010.148  0.384
2010 Pitt D, Gonzales E, Cross AH, Goldberg MP. Dysmyelinated axons in shiverer mice are highly vulnerable to alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated toxicity. Brain Research. 1309: 146-54. PMID 19896473 DOI: 10.1016/J.Brainres.2009.10.066  0.518
2003 Pitt D, Nagelmeier IE, Wilson HC, Raine CS. Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis. Neurology. 61: 1113-20. PMID 14581674 DOI: 10.1212/01.Wnl.0000090564.88719.37  0.523
2003 Gaupp S, Pitt D, Kuziel WA, Cannella B, Raine CS. Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains. The American Journal of Pathology. 162: 139-50. PMID 12507897 DOI: 10.1016/S0002-9440(10)63805-9  0.512
2001 Werner P, Pitt D, Raine CS. Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Annals of Neurology. 50: 169-80. PMID 11506399 DOI: 10.1002/Ana.1077  0.584
2000 Werner P, Pitt D, Raine CS. Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis? Journal of Neural Transmission. Supplementum. 375-85. PMID 11205156 DOI: 10.1007/978-3-7091-6301-6_27  0.592
2000 Cannella B, Pitt D, Capello E, Raine CS. Insulin-like growth factor-1 fails to enhance central nervous system myelin repair during autoimmune demyelination. The American Journal of Pathology. 157: 933-43. PMID 10980132 DOI: 10.1016/S0002-9440(10)64606-8  0.482
2000 Pitt D, Werner P, Raine CS. Glutamate excitotoxicity in a model of multiple sclerosis. Nature Medicine. 6: 67-70. PMID 10613826 DOI: 10.1038/71555  0.588
1999 Cannella B, Pitt D, Marchionni M, Raine CS. Neuregulin and erbB receptor expression in normal and diseased human white matter. Journal of Neuroimmunology. 100: 233-42. PMID 10695733 DOI: 10.1016/S0165-5728(99)00201-5  0.558
1999 Zeine R, Cannella B, Pitt D, Raine CS. PERFORIN EXPRESSION IN DEMYELINATIVE LESIONS OF MULTIPLE SCLEROSIS, AND A ROLE FOR PERFORIN IN THE REGULATION OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS Journal of Neuropathology and Experimental Neurology. 58: 564. DOI: 10.1097/00005072-199905000-00232  0.564
1998 Pitt D, Kuziel W, Charles P, Cannella B, Raine C. Experimental autoimmune encephalomyelitis in chemokine receptor deficient mice Journal of Neuroimmunology. 90: 60. DOI: 10.1016/S0165-5728(98)91536-3  0.439
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