Adam C Kaufman - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Alzheimer's Disease, Neuroplasticity, Hearing

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, et al. Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists. Cell Reports. 26: 1368. PMID 30699361 DOI: 10.1016/j.celrep.2019.01.064  0.78
2019 Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, et al. Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists. Cell Reports. 26: 145-158.e8. PMID 30605671 DOI: 10.1016/J.Celrep.2018.12.021  0.789
2017 Salazar SV, Gallardo C, Kaufman AC, Herber CS, Haas LT, Robinson S, Manson JC, Lee MK, Strittmatter SM. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28842420 DOI: 10.1523/Jneurosci.0722-17.2017  0.755
2017 Takahashi H, Klein ZA, Bhagat SM, Kaufman AC, Kostylev MA, Ikezu T, Strittmatter SM. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathologica. PMID 28070672 DOI: 10.1007/S00401-017-1668-Z  0.722
2015 Haas LT, Salazar SV, Kostylev MA, Um JW, Kaufman AC, Strittmatter SM. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain : a Journal of Neurology. PMID 26667279 DOI: 10.1093/Brain/Awv356  0.749
2015 Kostylev MA, Kaufman AC, Nygaard HB, Patel P, Haas LT, Gunther EC, Vortmeyer A, Strittmatter SM. Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models. The Journal of Biological Chemistry. 290: 17415-38. PMID 26018073 DOI: 10.1074/Jbc.M115.643577  0.789
2015 Nygaard HB, Kaufman AC, Sekine-Konno T, Huh LL, Going H, Feldman SJ, Kostylev MA, Strittmatter SM. Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer's disease mouse model. Alzheimer's Research & Therapy. 7: 25. PMID 25945128 DOI: 10.1186/S13195-015-0110-9  0.671
2015 Nygaard HB, Wagner AF, Bowen GS, Good SP, MacAvoy MG, Strittmatter KA, Kaufman AC, Rosenberg BJ, Sekine-Konno T, Varma P, Chen K, Koleske AJ, Reiman EM, Strittmatter SM, van Dyck CH. A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease. Alzheimer's Research & Therapy. 7: 35. PMID 25874001 DOI: 10.1186/S13195-015-0119-0  0.626
2015 Kaufman AC, Salazar SV, Haas LT, Yang J, Kostylev MA, Jeng AT, Robinson SA, Gunther EC, van Dyck CH, Nygaard HB, Strittmatter SM. Fyn inhibition rescues established memory and synapse loss in Alzheimer mice. Annals of Neurology. 77: 953-71. PMID 25707991 DOI: 10.1002/Ana.24394  0.747
2015 Kaufman A, Kostylev M, Haas L, Salazar S, Strittmatter S. F5-02-02: Aß oligomer induced signal transduction at the post-synaptic density Alzheimer's & Dementia. 11: P305-P305. DOI: 10.1016/J.Jalz.2015.07.428  0.683
2014 Kelley BJ, Harel NY, Kim CY, Papademetris X, Coman D, Wang X, Hasan O, Kaufman A, Globinsky R, Staib LH, Cafferty WB, Hyder F, Strittmatter SM. Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery. Journal of Neurotrauma. 31: 1362-73. PMID 24779685 DOI: 10.1089/Neu.2013.3238  0.697
2014 Strittmatter S, Kostylev M, Kaufman A, Haas L, Heiss J, Gunther E, Nygaard H. A Synaptotoxic Pathway from Aβ oligomer to Prion Protein to mGluR5 to F kinase in Alzheimer's Disease Neurobiology of Aging. 35: S21. DOI: 10.1016/J.Neurobiolaging.2014.01.112  0.795
2013 Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ, Gunther EC, Nygaard HB, Strittmatter SM. Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. Neuron. 79: 887-902. PMID 24012003 DOI: 10.1016/J.Neuron.2013.06.036  0.629
2013 Couch BA, Kerrisk ME, Kaufman AC, Nygaard HB, Strittmatter SM, Koleske AJ. Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice. The Journal of Comparative Neurology. 521: 1395-408. PMID 23047754 DOI: 10.1002/Cne.23239  0.626
2013 Kaufman AC, Strittmatter SM. Role of cellular prion protein in the amyloid-β oligomer pathophysiology of Alzheimer's disease Prions and Diseases. 1: 35-48. DOI: 10.1007/978-1-4614-5305-5_3  0.627
2012 Nygaard H, Kaufman A, Huh L, Strittmatter S. Epileptiform discharges in transgenic Alzheimer's mice correlate with impairments in spatial memory and are reduced by ethosuximide Alzheimers & Dementia. 8: 202. DOI: 10.1016/J.Jalz.2012.05.555  0.582
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