| Year |
Citation |
Score |
| 2023 |
Leusmann S, Ménová P, Shanin E, Titz A, Rademacher C. Glycomimetics for the inhibition and modulation of lectins. Chemical Society Reviews. 52: 3663-3740. PMID 37232696 DOI: 10.1039/d2cs00954d |
0.632 |
|
| 2022 |
Shanina E, Kuhaudomlarp S, Siebs E, Fuchsberger FF, Denis M, da Silva Figueiredo Celestino Gomes P, Clausen MH, Seeberger PH, Rognan D, Titz A, Imberty A, Rademacher C. Targeting undruggable carbohydrate recognition sites through focused fragment library design. Communications Chemistry. 5: 64. PMID 36697615 DOI: 10.1038/s42004-022-00679-3 |
0.688 |
|
| 2022 |
Zhang H, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J, Che K, Kim D, Kagelmacher M, Kurzbach D, Nazaré M, Rademacher C. Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. Acs Chemical Biology. PMID 36153965 DOI: 10.1021/acschembio.2c00626 |
0.361 |
|
| 2022 |
Zhang H, Daněk O, Makarov D, Rádl S, Kim D, Ledvinka J, Vychodilová K, Hlaváč J, Lefèbre J, Denis M, Rademacher C, Ménová P. Drug-like Inhibitors of DC-SIGN Based on a Quinolone Scaffold. Acs Medicinal Chemistry Letters. 13: 935-942. PMID 35707152 DOI: 10.1021/acsmedchemlett.2c00067 |
0.383 |
|
| 2021 |
Siebs E, Shanina E, Kuhaudomlarp S, da Silva Figueiredo Celestino Gomes P, Fortin C, Seeberger PH, Rognan D, Rademacher C, Imberty A, Titz A. Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA. Chembiochem : a European Journal of Chemical Biology. PMID 34788491 DOI: 10.1002/cbic.202100563 |
0.668 |
|
| 2021 |
Wawrzinek R, Wamhoff EC, Lefebre J, Rentzsch M, Bachem G, Domeniconi G, Schulze J, Fuchsberger FF, Zhang H, Modenutti C, Schnirch L, Marti MA, Schwardt O, Bräutigam M, Guberman M, ... ... Rademacher C, et al. A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN. Journal of the American Chemical Society. 143: 18977-18988. PMID 34748320 DOI: 10.1021/jacs.1c07235 |
0.654 |
|
| 2021 |
Shanina E, Kuhaudomlarp S, Lal K, Seeberger PH, Imberty A, Rademacher C. Druggable allosteric sites in β-propeller lectins. Angewandte Chemie (International Ed. in English). PMID 34713573 DOI: 10.1002/anie.202109339 |
0.308 |
|
| 2020 |
Kuhaudomlarp S, Siebs E, Shanina E, Topin J, Joachim I, da Silva Figueiredo Celestino Gomes P, Varrot A, Rognan D, Rademacher C, Imberty A, Titz A. Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-binding Lectins. Angewandte Chemie (International Ed. in English). PMID 33314528 DOI: 10.1002/anie.202013217 |
0.686 |
|
| 2020 |
Bachem G, Wamhoff EC, Silberreis K, Kim D, Baukmann H, Fuchsberger F, Dernedde J, Rademacher C, Seitz O. Amplifying the chelate effect as rational approach to a DNA-scaffolded high affinity binder for Langerin. Angewandte Chemie (International Ed. in English). PMID 32749019 DOI: 10.1002/Anie.202006880 |
0.467 |
|
| 2020 |
Shanina E, Siebs E, Zhang H, Silva DV, Joachim I, Titz A, Rademacher C. Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa. Glycobiology. PMID 32573695 DOI: 10.1093/Glycob/Cwaa057 |
0.716 |
|
| 2020 |
Bellmann L, Zelle-Rieser C, Milne P, Resteu A, Tripp CH, Hermann-Kleiter N, Zaderer V, Wilflingseder D, Hörtnagl P, Theochari M, Schulze J, Rentzsch M, Del Frari B, Collin M, Rademacher C, et al. Notch-mediated generation of monocyte-derived Langerhans cells: Phenotype and function. The Journal of Investigative Dermatology. PMID 32522485 DOI: 10.1016/J.Jid.2020.05.098 |
0.316 |
|
| 2020 |
Mende M, Tsouka A, Heidepriem J, Paris G, Mattes DS, Eickelmann S, Bordoni V, Wawrzinek R, Fuchsberger FF, Seeberger PH, Rademacher C, Delbianco M, Mallagaray A, Loeffler FF. On-Chip Neo-Glycopeptide Synthesis for Multivalent Glycan Presentation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32315099 DOI: 10.1002/Chem.202001291 |
0.742 |
|
| 2019 |
Freichel T, Laaf D, Hoffmann M, Konietzny PB, Heine V, Wawrzinek R, Rademacher C, Snyder NL, Elling L, Hartmann L. Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3. Rsc Advances. 9: 23484-23497. PMID 35530592 DOI: 10.1039/c9ra05497a |
0.372 |
|
| 2019 |
Keller BG, Rademacher C. Allostery in C-type lectins. Current Opinion in Structural Biology. 62: 31-38. PMID 31838280 DOI: 10.1016/J.Sbi.2019.11.003 |
0.405 |
|
| 2019 |
Troelsen N, Shanina E, Gonzalez-Romero D, Danková D, Jensen I, Sniady K, Nami F, Zhang H, Rademacher C, Cuenda A, Gotfredsen C, Clausen MH. The 3F Library: Fluorinated Fsp3-rich Fragments for Expeditious 19F-NMR-based Screening. Angewandte Chemie (International Ed. in English). PMID 31724281 DOI: 10.1002/Anie.201913125 |
0.327 |
|
| 2019 |
Neuhaus K, Wamhoff EC, Freichel T, Grafmüller A, Rademacher C, Hartmann L. Asymmetrically Branched Precision Glycooligomers Targeting Langerin. Biomacromolecules. PMID 31600054 DOI: 10.1021/Acs.Biomac.9B00906 |
0.484 |
|
| 2019 |
van Dalen R, Fuchsberger FF, Rademacher C, van Strijp JAG, van Sorge NM. A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus. Journal of Innate Immunity. 1-10. PMID 31141812 DOI: 10.1159/000500547 |
0.313 |
|
| 2019 |
Wamhoff EC, Schulze J, Bellmann L, Rentzsch M, Bachem G, Fuchsberger FF, Rademacher J, Hermann M, Del Frari B, van Dalen R, Hartmann D, van Sorge NM, Seitz O, Stoitzner P, Rademacher C. A Specific, Glycomimetic Langerin Ligand for Human Langerhans Cell Targeting. Acs Central Science. 5: 808-820. PMID 31139717 DOI: 10.1021/Acscentsci.9B00093 |
0.352 |
|
| 2019 |
Schulze J, Rentzsch M, Kim D, Bellmann L, Stoitzner P, Rademacher C. A liposomal delivery platform for protein antigen delivery to Langerin-expressing cells. Biochemistry. PMID 31062587 DOI: 10.1021/Acs.Biochem.9B00402 |
0.311 |
|
| 2019 |
Aretz J, Rademacher C. Ranking Hits From Saturation Transfer Difference Nuclear Magnetic Resonance-Based Fragment Screening. Frontiers in Chemistry. 7: 215. PMID 31032246 DOI: 10.3389/Fchem.2019.00215 |
0.395 |
|
| 2019 |
Denavit V, Lainé D, Bouzriba C, Shanina E, Gillon É, Fortin S, Rademacher C, Imberty A, Giguére D. Stereoselective synthesis of fluorinated galactopyranosides as potential molecular probes on galactophilic proteins: assessment of monofluorogalactosides-LecA interactions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30690814 DOI: 10.1002/Chem.201806197 |
0.422 |
|
| 2019 |
Geissner A, Reinhardt A, Rademacher C, Johannssen T, Monteiro J, Lepenies B, Thépaut M, Fieschi F, Mrázková J, Wimmerova M, Schuhmacher F, Götze S, Grünstein D, Guo X, Hahm HS, et al. Microbe-focused glycan array screening platform. Proceedings of the National Academy of Sciences of the United States of America. PMID 30670663 DOI: 10.1073/Pnas.1800853116 |
0.423 |
|
| 2019 |
Freichel T, Laaf D, Hoffmann M, Konietzny PB, Heine V, Wawrzinek R, Rademacher C, Snyder NL, Elling L, Hartmann L. Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3 Rsc Advances. 9: 23484-23497. DOI: 10.1039/C9Ra05497A |
0.419 |
|
| 2018 |
Schulze J, Baukmann H, Wawrzinek R, Fuchsberger FF, Specker E, Aretz J, Nazaré M, Rademacher C. CellFy: A Cell-Based Fragment Screen against C-Type Lectins. Acs Chemical Biology. 13: 3229-3235. PMID 30480432 DOI: 10.1021/Acschembio.8B00875 |
0.405 |
|
| 2018 |
Ng S, Bennett NJ, Schulze J, Gao N, Rademacher C, Derda R. Genetically-encoded fragment-based discovery of glycopeptide ligands for DC-SIGN. Bioorganic & Medicinal Chemistry. PMID 30344001 DOI: 10.1016/J.Bmc.2018.08.036 |
0.418 |
|
| 2018 |
Aretz J, Anumala UR, Fuchsberger FF, Molavi N, Ziebart N, Zhang H, Nazaré M, Rademacher C. Allosteric Inhibition of a Mammalian Lectin. Journal of the American Chemical Society. 140: 14915-14925. PMID 30303367 DOI: 10.1021/Jacs.8B08644 |
0.463 |
|
| 2018 |
Tian GZ, Hu J, Zhang HX, Rademacher C, Zou XP, Zheng HN, Xu F, Wang XL, Linker T, Yin J. Synthesis and conformational analysis of linear homo- and heterooligomers from novel 2-C-branched sugar amino acids (SAAs). Scientific Reports. 8: 6625. PMID 29700416 DOI: 10.1038/S41598-018-24927-6 |
0.331 |
|
| 2018 |
Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, et al. High affinity sugar ligands of C-type lectin receptor langerin. Biochimica Et Biophysica Acta. PMID 29631057 DOI: 10.1016/J.Bbagen.2018.04.004 |
0.46 |
|
| 2017 |
Sommer R, Wagner S, Rox K, Varrot A, Hauck D, Wamhoff EC, Schreiber J, Ryckmans T, Brunner T, Rademacher C, Hartmann RW, Brönstrup M, Imberty A, Titz A. Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa. Journal of the American Chemical Society. PMID 29272578 DOI: 10.1021/Jacs.7B11133 |
0.679 |
|
| 2017 |
Aretz J, Baukmann H, Shanina E, Hanske J, Wawrzinek R, Zapol'skii VA, Seeberger PH, Kaufmann DE, Rademacher C. Corrigendum: Identification of Multiple Druggable Secondary Sites by Fragment Screening against DC-SIGN. Angewandte Chemie (International Ed. in English). 56: 12398. PMID 28961388 DOI: 10.1002/Anie.201708597 |
0.309 |
|
| 2017 |
Spiliotopoulos D, Wamhoff EC, Lolli G, Rademacher C, Caflisch A. Discovery of BAZ2A bromodomain ligands. European Journal of Medicinal Chemistry. 139: 564-572. PMID 28837921 DOI: 10.1016/J.Ejmech.2017.08.028 |
0.487 |
|
| 2017 |
Glas A, Wamhoff EC, Krüger DM, Rademacher C, Grossmann TN. Increased Conformational Flexibility of a Macrocycle-Receptor Complex Contributes to Reduced Dissociation Rates. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28777495 DOI: 10.1002/Chem.201702776 |
0.464 |
|
| 2017 |
Aretz J, Baukmann H, Shanina E, Hanske J, Wawrzinek R, Zapol'skii VA, Seeberger PH, Kaufmann DE, Rademacher C. Identification of Multiple Druggable Secondary Sites by Fragment Screening against DC-SIGN. Angewandte Chemie (International Ed. in English). PMID 28523851 DOI: 10.1002/Anie.201701943 |
0.452 |
|
| 2017 |
Spiliotopoulos D, Zhu J, Wamhoff EC, Deerain N, Marchand JR, Aretz J, Rademacher C, Caflisch A. Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters. PMID 28410781 DOI: 10.1016/J.Bmcl.2017.04.001 |
0.471 |
|
| 2017 |
Hanske J, Wawrzinek R, Geissner A, Wamhoff EC, Sellrie K, Schmidt H, Seeberger PH, Rademacher C. Calcium-independent activation of an allosteric network in Langerin by heparin oligosaccharides. Chembiochem : a European Journal of Chemical Biology. PMID 28198086 DOI: 10.1002/Cbic.201700027 |
0.433 |
|
| 2017 |
Aretz J, Baukmann H, Shanina E, Hanske J, Wawrzinek R, Zapol'skii VA, Seeberger PH, Kaufmann DE, Rademacher C. Identifikation sekundärer Bindestellen auf DC-SIGN mithilfe eines Fragment-Screenings Angewandte Chemie. 129: 7398-7402. DOI: 10.1002/Ange.201701943 |
0.309 |
|
| 2016 |
Hanske J, Schulze J, Aretz J, McBride R, Loll B, Schmidt H, Knirel Y, Rabsch W, Wahl MC, Paulson JC, Rademacher C. Bacterial polysaccharide specificity of the pattern recognition receptor Langerin is highly species dependent. The Journal of Biological Chemistry. PMID 27903635 DOI: 10.1074/Jbc.M116.751750 |
0.447 |
|
| 2016 |
Hanske J, Aleksić S, Ballaschk M, Jurk M, Shanina E, Beerbaum M, Schmieder P, Keller BG, Rademacher C. An intra-domain allosteric network modulates the calcium affinity of the C-type lectin receptor Langerin. Journal of the American Chemical Society. PMID 27560542 DOI: 10.1021/Jacs.6B05458 |
0.361 |
|
| 2016 |
Mallagaray A, Rademacher C, Parra F, Hansman G, Peters T. Sexually transmitted disease nuclear magnetic resonance titrations reveal complex multistep-binding of l-fucose to norovirus particles. Glycobiology. PMID 27496762 DOI: 10.1093/Glycob/Cww070 |
0.757 |
|
| 2016 |
Wamhoff EC, Hanske J, Schnirch L, Aretz J, Grube M, Varón Silva D, Rademacher C. (19)F NMR-Guided Design of Glycomimetic Langerin Ligands. Acs Chemical Biology. 11: 2407-13. PMID 27458873 DOI: 10.1021/Acschembio.6B00561 |
0.479 |
|
| 2016 |
Broecker F, Hanske J, Martin CE, Baek JY, Wahlbrink A, Wojcik F, Hartmann L, Rademacher C, Anish C, Seeberger PH. Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans. Nature Communications. 7: 11224. PMID 27091615 DOI: 10.1038/Ncomms11224 |
0.314 |
|
| 2016 |
Aretz J, Kondoh Y, Honda K, Anumala UR, Nazaré M, Watanabe N, Osada H, Rademacher C. Chemical fragment arrays for rapid druggability assessment. Chemical Communications (Cambridge, England). PMID 26890187 DOI: 10.1039/C5Cc10457B |
0.32 |
|
| 2016 |
Aretz J, Wratil PR, Wamhoff E, Nguyen HG, Reutter W, Rademacher C. Fragment-screening of N-acetylmannosamine kinase reveals non-carbohydrate inhibitors Canadian Journal of Chemistry. 94: 920-926. DOI: 10.1139/Cjc-2015-0603 |
0.361 |
|
| 2015 |
Lee CU, Hahne G, Hanske J, Bange T, Bier D, Rademacher C, Hennig S, Grossmann TN. Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes. Angewandte Chemie (International Ed. in English). PMID 26418532 DOI: 10.1002/Anie.201506338 |
0.312 |
|
| 2015 |
Rademacher C, Seeberger PH. High-Throughput Synthesis of Diverse Compound Collections for Lead Discovery and Optimization. Handbook of Experimental Pharmacology. PMID 26330259 DOI: 10.1007/164_2015_25 |
0.341 |
|
| 2014 |
Aretz J, Wamhoff EC, Hanske J, Heymann D, Rademacher C. Computational and experimental prediction of human C-type lectin receptor druggability. Frontiers in Immunology. 5: 323. PMID 25071783 DOI: 10.3389/Fimmu.2014.00323 |
0.429 |
|
| 2014 |
Glas A, Bier D, Hahne G, Rademacher C, Ottmann C, Grossmann TN. Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angewandte Chemie (International Ed. in English). 53: 2489-93. PMID 24504455 DOI: 10.1002/Anie.201310082 |
0.353 |
|
| 2014 |
Broecker F, Aretz J, Yang Y, Hanske J, Guo X, Reinhardt A, Wahlbrink A, Rademacher C, Anish C, Seeberger PH. Epitope recognition of antibodies against a yersinia pestis lipopolysaccharide trisaccharide component Acs Chemical Biology. 9: 867-873. PMID 24479563 DOI: 10.1021/Cb400925K |
0.357 |
|
| 2014 |
Ponader D, Maffre P, Aretz J, Pussak D, Ninnemann NM, Schmidt S, Seeberger PH, Rademacher C, Nienhaus GU, Hartmann L. Carbohydrate-Lectin recognition of sequence-defined heteromultivalent glycooligomers Journal of the American Chemical Society. 136: 2008-2016. PMID 24417254 DOI: 10.1021/Ja411582T |
0.486 |
|
| 2014 |
Glas A, Bier D, Hahne G, Rademacher C, Ottmann C, Grossmann TN. Back Cover: Constrained Peptides with Target-Adapted Cross-Links as Inhibitors of a Pathogenic Protein-Protein Interaction (Angew. Chem. Int. Ed. 9/2014) Angewandte Chemie International Edition. 53: 2510-2510. DOI: 10.1002/Anie.201400778 |
0.328 |
|
| 2013 |
Macauley MS, Pfrengle F, Rademacher C, Nycholat CM, Gale AJ, von Drygalski A, Paulson JC. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. The Journal of Clinical Investigation. 123: 3074-83. PMID 23722906 DOI: 10.1172/Jci69187 |
0.322 |
|
| 2013 |
Rillahan CD, Schwartz E, Rademacher C, McBride R, Rangarajan J, Fokin VV, Paulson JC. On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7. Acs Chemical Biology. 8: 1417-22. PMID 23597400 DOI: 10.1021/Cb400125W |
0.438 |
|
| 2012 |
Nycholat CM, Rademacher C, Kawasaki N, Paulson JC. In silico-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages. Journal of the American Chemical Society. 134: 15696-9. PMID 22967315 DOI: 10.1021/Ja307501E |
0.397 |
|
| 2012 |
Landström J, Persson K, Rademacher C, Lundborg M, Wakarchuk W, Peters T, Widmalm G. Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase. Glycoconjugate Journal. 29: 491-502. PMID 22711644 DOI: 10.1007/S10719-012-9411-4 |
0.68 |
|
| 2012 |
Rademacher C, Bru T, McBride R, Robison E, Nycholat CM, Kremer EJ, Paulson JC. A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein. Glycobiology. 22: 1086-91. PMID 22522600 DOI: 10.1093/Glycob/Cws073 |
0.39 |
|
| 2012 |
Rademacher C, Paulson JC. Glycan fingerprints: calculating diversity in glycan libraries. Acs Chemical Biology. 7: 829-34. PMID 22373368 DOI: 10.1021/Cb300003Z |
0.329 |
|
| 2012 |
Fiege B, Rademacher C, Cartmell J, Kitov PI, Parra F, Peters T. Molecular details of the recognition of blood group antigens by a human norovirus as determined by STD NMR spectroscopy. Angewandte Chemie (International Ed. in English). 51: 928-32. PMID 22170811 DOI: 10.1002/Anie.201105719 |
0.562 |
|
| 2011 |
Rademacher C, Guiard J, Kitov PI, Fiege B, Dalton KP, Parra F, Bundle DR, Peters T. Targeting norovirus infection-multivalent entry inhibitor design based on NMR experiments. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7442-53. PMID 21567493 DOI: 10.1002/Chem.201003432 |
0.736 |
|
| 2011 |
Zeng Y, Rademacher C, Nycholat CM, Futakawa S, Lemme K, Ernst B, Paulson JC. High affinity sialoside ligands of myelin associated glycoprotein. Bioorganic & Medicinal Chemistry Letters. 21: 5045-9. PMID 21561770 DOI: 10.1016/J.Bmcl.2011.04.068 |
0.375 |
|
| 2010 |
Rademacher C, Landström J, Sindhuwinata N, Palcic MM, Widmalm G, Peters T. NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments. Glycoconjugate Journal. 27: 349-58. PMID 20217221 DOI: 10.1007/S10719-010-9282-5 |
0.669 |
|
| 2008 |
Rademacher C, Peters T. Molecular recognition of ligands by native viruses and virus-like particles as studied by NMR experiments. Topics in Current Chemistry. 273: 183-202. PMID 23605463 DOI: 10.1007/128_2007_19 |
0.611 |
|
| 2008 |
Rademacher C, Krishna NR, Palcic M, Parra F, Peters T. NMR experiments reveal the molecular basis of receptor recognition by a calicivirus. Journal of the American Chemical Society. 130: 3669-75. PMID 18302385 DOI: 10.1021/Ja710854R |
0.61 |
|
| 2007 |
Rademacher C, Shoemaker GK, Kim HS, Zheng RB, Taha H, Liu C, Nacario RC, Schriemer DC, Klassen JS, Peters T, Lowary TL. Ligand specificity of CS-35, a monoclonal antibody that recognizes mycobacterial lipoarabinomannan: a model system for oligofuranoside-protein recognition. Journal of the American Chemical Society. 129: 10489-502. PMID 17672460 DOI: 10.1021/Ja0723380 |
0.673 |
|
| 2006 |
Angulo J, Rademacher C, Biet T, Benie AJ, Blume A, Peters H, Palcic M, Parra F, Peters T. NMR analysis of carbohydrate-protein interactions. Methods in Enzymology. 416: 12-30. PMID 17113857 DOI: 10.1016/S0076-6879(06)16002-4 |
0.736 |
|
| 2005 |
Peters H, Kusov YY, Meyer S, Benie AJ, Bäuml E, Wolff M, Rademacher C, Peters T, Gauss-Müller V. Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization. The Biochemical Journal. 385: 363-70. PMID 15361063 DOI: 10.1042/Bj20041153 |
0.603 |
|
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