John David York - Publications

Affiliations: 
Pharmacology and Cancer Biology Duke University School of Medicine, Durham, NC, United States 
Website:
https://medschool.duke.edu/about-us/our-faculty/john-david-york

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang T, Hale AT, Guo S, York JD. Coordinated inositide lipid-phosphatase activities of synaptojanin modulates actin cytoskeleton organization. Advances in Biological Regulation. 101012. PMID 38220563 DOI: 10.1016/j.jbior.2023.101012  0.302
2020 Dollins DE, Bai W, Fridy PC, Otto JC, Neubauer JL, Gattis SG, Mehta KPM, York JD. Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 32303658 DOI: 10.1073/Pnas.1908875117  0.465
2020 Hale AT, Clarke BP, York JD. Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells. Methods in Molecular Biology (Clifton, N.J.). 2091: 83-92. PMID 31773572 DOI: 10.1007/978-1-0716-0167-9_7  0.383
2019 Clarke BP, Logeman BL, Hale AT, Luka Z, York JD. A synthetic biological approach to reconstitution of inositide signaling pathways in bacteria. Advances in Biological Regulation. 100637. PMID 31378699 DOI: 10.1016/J.Jbior.2019.100637  0.44
2019 McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, Guibao CD, Diep J, Nourse A, Cai CR, Wu H, Kalathur RC, Green DR, York JD, Carette JE, Moldoveanu T. Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites. Cell Chemical Biology. PMID 31031142 DOI: 10.1016/J.Chembiol.2019.03.010  0.394
2018 Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, ... ... York JD, et al. MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. Molecular Cell. 70: 936-948.e7. PMID 29883610 DOI: 10.1016/J.Molcel.2018.05.010  0.446
2017 Hatch AJ, Odom AR, York JD. Inositol phosphate multikinase dependent transcriptional control. Advances in Biological Regulation. PMID 28342784 DOI: 10.1016/J.Jbior.2017.03.001  0.443
2016 York JD, Vagelos PR. A tribute to Philip W. Majerus. The Journal of Clinical Investigation. 126: 3161-4. PMID 27584729 DOI: 10.1172/JCI89724  0.442
2015 Seeds AM, Tsui MM, Sunu C, Spana EP, York JD. Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 26647185 DOI: 10.1073/Pnas.1514684112  0.426
2014 Emptage RP, Tonthat NK, York JD, Schumacher MA, Zhou P. Structural basis of lipid binding for the membrane-embedded tetraacyldisaccharide-1-phosphate 4'-kinase LpxK. The Journal of Biological Chemistry. 289: 24059-68. PMID 25023290 DOI: 10.1074/Jbc.M114.589986  0.361
2014 Pulloor NK, Nair S, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, García-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, et al. Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. Plos Pathogens. 10: e1003981. PMID 24586175 DOI: 10.1371/Journal.Ppat.1003981  0.409
2014 Hudson BH, York JD. Tissue-specific regulation of 3'-nucleotide hydrolysis and nucleolar architecture. Advances in Biological Regulation. 54: 208-13. PMID 24309248 DOI: 10.1016/J.Jbior.2013.11.002  0.354
2013 Hudson BH, Frederick JP, Drake LY, Megosh LC, Irving RP, York JD. Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 5040-5. PMID 23479625 DOI: 10.1073/Pnas.1205001110  0.359
2013 Emptage RP, Pemble CW, York JD, Raetz CR, Zhou P. Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis. Biochemistry. 52: 2280-90. PMID 23464738 DOI: 10.1021/Bi400097Z  0.417
2013 Banfic H, Bedalov A, York JD, Visnjic D. Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 288: 1717-25. PMID 23179856 DOI: 10.1074/Jbc.M112.412288  0.405
2012 Endo-Streeter S, Tsui MK, Odom AR, Block J, York JD. Structural studies and protein engineering of inositol phosphate multikinase. The Journal of Biological Chemistry. 287: 35360-9. PMID 22896696 DOI: 10.1074/Jbc.M112.365031  0.487
2012 Hudson BH, York JD. Roles for nucleotide phosphatases in sulfate assimilation and skeletal disease. Advances in Biological Regulation. 52: 229-38. PMID 22100882 DOI: 10.1016/J.Advenzreg.2011.11.002  0.393
2010 Hatch AJ, York JD. SnapShot: Inositol phosphates. Cell. 143: 1030-1030.e1. PMID 21145466 DOI: 10.1016/J.Cell.2010.11.045  0.347
2010 Otto JC, York JD. Molecular manipulation and analysis of inositol phosphate and pyrophosphate levels in Mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 645: 47-60. PMID 20645180 DOI: 10.1007/978-1-60327-175-2_3  0.426
2010 Monserrate JP, York JD. Inositol phosphate synthesis and the nuclear processes they affect. Current Opinion in Cell Biology. 22: 365-73. PMID 20359876 DOI: 10.1016/J.Ceb.2010.03.006  0.343
2010 Tsui MM, York JD. Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes. Advances in Enzyme Regulation. 50: 324-37. PMID 20006638 DOI: 10.1016/J.Advenzreg.2009.12.002  0.392
2009 Padmanabhan U, Dollins DE, Fridy PC, York JD, Downes CP. Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates. The Journal of Biological Chemistry. 284: 10571-82. PMID 19208622 DOI: 10.1074/Jbc.M900752200  0.426
2009 Majerus PW, York JD. Phosphoinositide phosphatases and disease. Journal of Lipid Research. 50: S249-54. PMID 19001665 DOI: 10.1194/Jlr.R800072-Jlr200  0.54
2009 Lin H, Fridy PC, Ribeiro AA, Choi JH, Barma DK, Vogel G, Falck JR, Shears SB, York JD, Mayr GW. Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases. The Journal of Biological Chemistry. 284: 1863-72. PMID 18981179 DOI: 10.1074/Jbc.M805686200  0.406
2008 Frederick JP, Tafari AT, Wu SM, Megosh LC, Chiou ST, Irving RP, York JD. A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11605-12. PMID 18695242 DOI: 10.1073/Pnas.0801182105  0.354
2008 York JD, Lew DJ. IP7 guards the CDK gate. Nature Chemical Biology. 4: 16-7. PMID 18084274 DOI: 10.1038/Nchembio0108-16  0.362
2007 Otto JC, Mulugu S, Fridy PC, Chiou ST, Armbruster BN, Ribeiro AA, York JD. Biochemical analysis of inositol phosphate kinases. Methods in Enzymology. 434: 171-85. PMID 17954248 DOI: 10.1016/S0076-6879(07)34010-X  0.446
2007 Otto JC, Kelly P, Chiou ST, York JD. Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinases. Proceedings of the National Academy of Sciences of the United States of America. 104: 15653-8. PMID 17895383 DOI: 10.1073/Pnas.0705729104  0.44
2007 Fridy PC, Otto JC, Dollins DE, York JD. Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases. The Journal of Biological Chemistry. 282: 30754-62. PMID 17690096 DOI: 10.1074/Jbc.M704656200  0.458
2007 Seeds AM, Frederick JP, Tsui MM, York JD. Roles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biology. Advances in Enzyme Regulation. 47: 10-25. PMID 17467778 DOI: 10.1016/J.Advenzreg.2006.12.019  0.473
2007 Lee YS, Mulugu S, York JD, O'Shea EK. Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science (New York, N.Y.). 316: 109-12. PMID 17412959 DOI: 10.1126/Science.1139080  0.403
2007 Mulugu S, Bai W, Fridy PC, Bastidas RJ, Otto JC, Dollins DE, Haystead TA, Ribeiro AA, York JD. A conserved family of enzymes that phosphorylate inositol hexakisphosphate. Science (New York, N.Y.). 316: 106-9. PMID 17412958 DOI: 10.1126/Science.1139099  0.49
2007 Seeds AM, York JD. Inositol polyphosphate kinases: regulators of nuclear function. Biochemical Society Symposium. 183-97. PMID 17233590 DOI: 10.1042/Bss0740183  0.433
2006 DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ. APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2. Circulation Research. 99: 829-36. PMID 16973905 DOI: 10.1161/01.Res.0000245479.03190.9F  0.363
2006 Stevenson-Paulik J, Chiou ST, Frederick JP, dela Cruz J, Seeds AM, Otto JC, York JD. Inositol phosphate metabolomics: merging genetic perturbation with modernized radiolabeling methods. Methods (San Diego, Calif.). 39: 112-21. PMID 16829132 DOI: 10.1016/J.Ymeth.2006.05.012  0.392
2006 York JD. Regulation of nuclear processes by inositol polyphosphates. Biochimica Et Biophysica Acta. 1761: 552-9. PMID 16781889 DOI: 10.1016/J.Bbalip.2006.04.014  0.445
2005 Stevenson-Paulik J, Bastidas RJ, Chiou ST, Frye RA, York JD. Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases. Proceedings of the National Academy of Sciences of the United States of America. 102: 12612-7. PMID 16107538 DOI: 10.1073/Pnas.0504172102  0.412
2005 Seeds AM, Bastidas RJ, York JD. Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 280: 27654-61. PMID 15944147 DOI: 10.1074/Jbc.M505089200  0.455
2005 Frederick JP, Mattiske D, Wofford JA, Megosh LC, Drake LY, Chiou ST, Hogan BL, York JD. An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production. Proceedings of the National Academy of Sciences of the United States of America. 102: 8454-9. PMID 15939867 DOI: 10.1073/Pnas.0503706102  0.455
2005 Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4336-41. PMID 15784746 DOI: 10.1073/Pnas.0408107102  0.357
2005 Spiegelberg BD, Dela Cruz J, Law TH, York JD. Alteration of lithium pharmacology through manipulation of phosphoadenosine phosphate metabolism. The Journal of Biological Chemistry. 280: 5400-5. PMID 15583009 DOI: 10.1074/Jbc.M407890200  0.422
2005 York SJ, Armbruster BN, Greenwell P, Petes TD, York JD. Inositol diphosphate signaling regulates telomere length. The Journal of Biological Chemistry. 280: 4264-9. PMID 15561716 DOI: 10.1074/Jbc.M412070200  0.435
2005 Fujii M, York JD. A role for rat inositol polyphosphate kinases rIPK2 and rIPK1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells. The Journal of Biological Chemistry. 280: 1156-64. PMID 15528195 DOI: 10.1074/Jbc.M412006200  0.358
2004 York JD, Hunter T. Signal transduction. Unexpected mediators of protein phosphorylation. Science (New York, N.Y.). 306: 2053-5. PMID 15604398 DOI: 10.1126/Science.1107225  0.426
2004 Seeds AM, Sandquist JC, Spana EP, York JD. A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster. The Journal of Biological Chemistry. 279: 47222-32. PMID 15322119 DOI: 10.1074/Jbc.M408295200  0.411
2003 Plattner R, Irvin BJ, Guo S, Blackburn K, Kazlauskas A, Abraham RT, York JD, Pendergast AM. A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nature Cell Biology. 5: 309-19. PMID 12652307 DOI: 10.1038/Ncb949  0.395
2002 Stevenson-Paulik J, Odom AR, York JD. Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases. The Journal of Biological Chemistry. 277: 42711-8. PMID 12226109 DOI: 10.1074/Jbc.M209112200  0.416
2002 Alb JG, Phillips SE, Rostand K, Cui X, Pinxteren J, Cotlin L, Manning T, Guo S, York JD, Sontheimer H, Collawn JF, Bankaitis VA. Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells. Molecular Biology of the Cell. 13: 739-54. PMID 11907258 DOI: 10.1091/Mbc.01-09-0457  0.35
2002 Kontos CD, Cha EH, York JD, Peters KG. The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. Molecular and Cellular Biology. 22: 1704-13. PMID 11865050 DOI: 10.1128/Mcb.22.6.1704-1713.2002  0.444
2001 Tsujishita Y, Guo S, Stolz LE, York JD, Hurley JH. Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell. 105: 379-89. PMID 11348594 DOI: 10.1016/S0092-8674(01)00326-9  0.383
2000 Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, Grinstein S. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. The Journal of Cell Biology. 151: 1353-68. PMID 11134066 DOI: 10.1083/Jcb.151.7.1353  0.367
2000 Ives EB, Nichols J, Wente SR, York JD. Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases. The Journal of Biological Chemistry. 275: 36575-83. PMID 10960485 DOI: 10.1074/Jbc.M007586200  0.433
2000 Aharonovitz O, Zaun HC, Balla T, York JD, Orlowski J, Grinstein S. Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. The Journal of Cell Biology. 150: 213-24. PMID 10893269 DOI: 10.1083/Jcb.150.1.213  0.357
2000 Odom AR, Stahlberg A, Wente SR, York JD. A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. Science (New York, N.Y.). 287: 2026-9. PMID 10720331 DOI: 10.1126/Science.287.5460.2026  0.436
1999 Meyer T, York JD. Calcium-myristoyl switches turn on new lights. Nature Cell Biology. 1: E93-5. PMID 10559930 DOI: 10.1038/12090  0.341
1999 Rivas MP, Kearns BG, Xie Z, Guo S, Sekar MC, Hosaka K, Kagiwada S, York JD, Bankaitis VA. Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. Molecular Biology of the Cell. 10: 2235-50. PMID 10397762 DOI: 10.1091/Mbc.10.7.2235  0.404
1999 York JD, Odom AR, Murphy R, Ives EB, Wente SR. A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science (New York, N.Y.). 285: 96-100. PMID 10390371 DOI: 10.1126/Science.285.5424.96  0.35
1999 Spiegelberg BD, Xiong JP, Smith JJ, Gu RF, York JD. Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate. The Journal of Biological Chemistry. 274: 13619-28. PMID 10224133 DOI: 10.1074/Jbc.274.19.13619  0.425
1999 Guo S, Stolz LE, Lemrow SM, York JD. SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. The Journal of Biological Chemistry. 274: 12990-5. PMID 10224048 DOI: 10.1074/Jbc.274.19.12990  0.449
1999 Basu SS, York JD, Raetz CR. A phosphotransferase that generates phosphatidylinositol 4-phosphate (PtdIns-4-P) from phosphatidylinositol and lipid A in Rhizobium leguminosarum. A membrane-bound enzyme linking lipid a and ptdins-4-p biosynthesis. The Journal of Biological Chemistry. 274: 11139-49. PMID 10196199 DOI: 10.1074/Jbc.274.16.11139  0.382
1998 Kontos CD, Stauffer TP, Yang WP, York JD, Huang L, Blanar MA, Meyer T, Peters KG. Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt. Molecular and Cellular Biology. 18: 4131-40. PMID 9632797 DOI: 10.1128/Mcb.18.7.4131  0.429
1998 Stolz LE, Kuo WJ, Longchamps J, Sekhon MK, York JD. INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype. The Journal of Biological Chemistry. 273: 11852-61. PMID 9565610 DOI: 10.1074/Jbc.273.19.11852  0.373
1995 York JD, Ponder JW, Majerus PW. Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proceedings of the National Academy of Sciences of the United States of America. 92: 5149-53. PMID 7761465 DOI: 10.1073/Pnas.92.11.5149  0.571
1994 York JD, Chen ZW, Ponder JW, Chauhan AK, Mathews FS, Majerus PW. Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells. Journal of Molecular Biology. 236: 584-9. PMID 8107142 DOI: 10.1006/Jmbi.1994.1167  0.551
1994 York JD, Ponder JW, Chen ZW, Mathews FS, Majerus PW. Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution. Biochemistry. 33: 13164-71. PMID 7947723 DOI: 10.1021/Bi00249A002  0.513
1993 York JD, Veile RA, Donis-Keller H, Majerus PW. Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 90: 5833-7. PMID 8390685 DOI: 10.1073/Pnas.90.12.5833  0.536
1991 Neuwald AF, York JD, Majerus PW. Diverse proteins homologous to inositol monophosphatase. Febs Letters. 294: 16-8. PMID 1660408 DOI: 10.1016/0014-5793(91)81332-3  0.567
1991 Gu MX, York JD, Warshawsky I, Majerus PW. Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. Proceedings of the National Academy of Sciences of the United States of America. 88: 5867-71. PMID 1648233 DOI: 10.1073/Pnas.88.13.5867  0.571
1990 York JD, Majerus PW. Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 87: 9548-52. PMID 2175905 DOI: 10.1073/Pnas.87.24.9548  0.567
Show low-probability matches.