Year |
Citation |
Score |
2021 |
Alasady MJ, Terry AR, Pierce AD, Cavalier MC, Blaha CS, Adipietro KA, Wilder PT, Weber DJ, Hay N. The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling. Plos One. 16: e0256238. PMID 34411141 DOI: 10.1371/journal.pone.0256238 |
0.736 |
|
2016 |
Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, Blaner WS, Frank J, Quadro L, Weber DJ, Shapiro L, et al. Structure of the STRA6 receptor for retinol uptake. Science (New York, N.Y.). 353. PMID 27563101 DOI: 10.1126/Science.Aad8266 |
0.753 |
|
2016 |
Cavalier MC, Melville Z, Aligholizadeh E, Raman EP, Yu W, Fang L, Alasady M, Pierce AD, Wilder PT, MacKerell AD, Weber DJ. Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography. Acta Crystallographica. Section D, Structural Biology. 72: 753-760. PMID 27303795 DOI: 10.1107/S2059798316005532 |
0.754 |
|
2016 |
Cavalier MC, Ansari MI, Pierce AD, Wilder PT, McKnight LE, Raman EP, Neau DB, Bezawada P, Alasady MJ, Charpentier TH, Varney K, Toth EA, MacKerell AD, Coop A, Weber DJ. Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. Journal of Medicinal Chemistry. PMID 26727270 DOI: 10.1021/Acs.Jmedchem.5B01369 |
0.682 |
|
2016 |
Cavalier MC, Wilder PT, Luci D, Maloney DJ, Fang L, Ansari MI, MacKerell AD, Coop A, Jadhav A, Weber DJ. Abstract 1358: Structure-based drug design of 3-site binding, high affinity inhibitors of S100B in malignant melanoma Cancer Research. 76: 1358-1358. DOI: 10.1158/1538-7445.Am2016-1358 |
0.743 |
|
2015 |
Stowe SD, Cavalier MC, Godoy-Ruiz R, Varney KJ, Wilder PT, Gartenhaus RB, Weber DJ. Abstract 2454: Targeting the translational enhancer complex MCT-1:DenR to disrupt NHL survival Cancer Research. 75: 2454-2454. DOI: 10.1158/1538-7445.Am2015-2454 |
0.761 |
|
2015 |
Melville Z, Varney K, Cavalier M, Stowe S, Weber D, Toth E, Weber D. Characterizing a New Metal Binding Site in S100B Biophysical Journal. 108: 48a. DOI: 10.1016/J.Bpj.2014.11.293 |
0.745 |
|
2015 |
Stowe SD, Cavalier MC, Godoy-Ruiz R, Varney KM, Wilder PT, Gartenhaus RB, Weber DJ. Characterizing the MCT-1:DenR Complex, a Translational Enhancer for Lymphoma Survival Biophysical Journal. 108: 219a. DOI: 10.1016/J.Bpj.2014.11.1212 |
0.742 |
|
2015 |
Cavalier MC, Weber DJ. Targeting Melanoma with Small Molecules: Inhibitors of the Calcium-Binding Protein S100B Biophysical Journal. 108: 214a. DOI: 10.1016/J.Bpj.2014.11.1181 |
0.66 |
|
2014 |
Cavalier MC, Pierce AD, Wilder PT, Alasady MJ, Hartman KG, Neau DB, Foley TL, Jadhav A, Maloney DJ, Simeonov A, Toth EA, Weber DJ. Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53: 6628-40. PMID 25268459 DOI: 10.1021/Bi5005552 |
0.757 |
|
2014 |
Cavalier MC. Abstract 3221: Covalent inhibitors of S100B (SBiXs) in malignant melanoma Cancer Research. 74: 3221-3221. DOI: 10.1158/1538-7445.Am2014-3221 |
0.584 |
|
2013 |
Cavalier MC, McKnight L, Weber D, Wilder P. Abstract 2226: Structure/function characterization of SBi4225, a novel inhibitor of the calcium-binding protein S100B. Cancer Research. 73: 2226-2226. DOI: 10.1158/1538-7445.Am2013-2226 |
0.793 |
|
2013 |
Cavalier M, Wilder PT, Coop A, MacKerell A, Weber DJ. Abstract B103: Inhibitors of S100B (SBiXs) in malignant melanoma. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B103 |
0.756 |
|
2012 |
Cavalier MC, Yim YS, Asamizu S, Neau D, Almabruk KH, Mahmud T, Lee YH. Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex Plos One. 7. PMID 23028689 DOI: 10.1371/Journal.Pone.0044934 |
0.395 |
|
2012 |
Cavalier MC, Kim SG, Neau D, Lee YH. Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function Proteins: Structure, Function and Bioinformatics. 80: 1143-1153. PMID 22275052 DOI: 10.1002/Prot.24015 |
0.344 |
|
2011 |
Crochet RB, Cavalier MC, Seo M, Kim JD, Yim YS, Park SJ, Lee YH. Investigating combinatorial approaches in virtual screening on human inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a case study for small molecule kinases. Analytical Biochemistry. 418: 143-8. PMID 21771574 DOI: 10.1016/J.Ab.2011.06.035 |
0.31 |
|
2007 |
Kim SG, Cavalier M, El-Maghrabi MR, Lee YH. A direct substrate-substrate interaction found in the kinase domain of the bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Journal of Molecular Biology. 370: 14-26. PMID 17499765 DOI: 10.1016/J.Jmb.2007.03.038 |
0.368 |
|
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