David Scott - Publications

Massachusetts Institute of Technology, Cambridge, MA, United States 

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shang X, Scott D, Chan RK, Zhang L, He M. Association of pulmonary function with cognitive decline in older adults: a nationwide longitudinal study in China. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 33824989 DOI: 10.1093/gerona/glab096  0.36
2021 Nguyen H, Perry A, Skrabek P, Nasr M, Herrera AF, Bedell V, Murata-Collins J, Pillai R, Xu M, Chen L, Chan WC, Weisenburger DD, Scott DW, Song JY. Validation of the double-hit gene expression signature (DLBCL90) in an independent cohort of patients with diffuse large B-cell lymphoma of germinal center origin. The Journal of Molecular Diagnostics : Jmd. PMID 33636392 DOI: 10.1016/j.jmoldx.2021.02.005  0.32
2021 Scott DW, Wang Z. Robust Multiple Regression. Entropy (Basel, Switzerland). 23. PMID 33435467 DOI: 10.3390/e23010088  0.48
2021 Song JY, Perry AM, Herrera AF, Chen L, Skrabek P, Nasr M, Ottesen R, Nikowitz J, Bedell V, Murata-Collins JL, Li Y, McCarthy C, Pillai RK, Wang J, Wu X, ... ... Scott DW, et al. Double-hit signature with TP53 abnormalities predicts poor survival in patients with germinal center type diffuse large B-cell lymphoma treated with R-CHOP. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33414134 DOI: 10.1158/1078-0432.CCR-20-2378  0.32
2020 Mollasalehi N, Francois-Moutal L, Scott DD, Tello JA, Williams H, Mahoney B, Carlson JM, Dong Y, Li X, Miranda VG, Gokhale V, Wang W, Barmada SJ, Khanna M. An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties. Acs Chemical Biology. PMID 33044808 DOI: 10.1021/acschembio.0c00494  0.32
2019 Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, et al. Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. Nature Reviews. Microbiology. PMID 31857715 DOI: 10.1038/S41579-019-0299-X  1
2019 Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F. A Survey of Genome Editing Activity for 16 Cas12a Orthologs. The Keio Journal of Medicine. PMID 31723075 DOI: 10.2302/Kjm.2019-0009-Oa  1
2019 Nowakowski GS, Chiappella A, Witzig TE, Scott DW, Spina M, Gascoyne RD, Zhang L, Russo J, Kang J, Zhang J, Xu Y, Vitolo U. Variable global distribution of cell-of-origin from the ROBUST phase 3 study in diffuse large B-cell lymphoma. Haematologica. PMID 31221781 DOI: 10.3324/haematol.2019.220475  0.36
2019 Scott DD, Francois-Moutal L, Kumirov VK, Khanna M. H, N and C backbone assignment of apo TDP-43 RNA recognition motifs. Biomolecular Nmr Assignments. PMID 30694439 DOI: 10.1007/S12104-018-09870-X  0.32
2018 François-Moutal L, Scott DD, Perez-Miller S, Gokhale V, Khanna M, Khanna R. Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels. Channels (Austin, Tex.). 1-9. PMID 30081699 DOI: 10.1080/19336950.2018.1491244  0.32
2017 Zhu Y, Zhao S, Deng Y, Gordillo R, Ghaben AL, Shao M, Zhang F, Xu P, Li Y, Cao H, Zagnitko O, Scott DA, Gupta RK, Xing C, Zhang BB, et al. Hepatic GALE Regulates Whole Body Glucose Homeostasis by Modulating Tff3 Expression. Diabetes. PMID 28877911 DOI: 10.2337/Db17-0323  1
2017 Scott DA, Zhang F. Implications of human genetic variation in CRISPR-based therapeutic genome editing. Nature Medicine. PMID 28759051 DOI: 10.1038/Nm.4377  1
2017 Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks. Nature Communications. 8: 15058. PMID 28497783 DOI: 10.1038/Ncomms15058  1
2017 Shang X, Scott D, Hodge AM, Giles GG, Ebeling PR, Sanders KM. Reply to G-C Chen et al. The American Journal of Clinical Nutrition. 105: 1016. PMID 28373312 DOI: 10.3945/Ajcn.116.149468  0.36
2017 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Erratum: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. 35: 178. PMID 28178246 DOI: 10.1038/Nbt0217-178B  1
2017 Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV. Diversity and evolution of class 2 CRISPR-Cas systems. Nature Reviews. Microbiology. PMID 28111461 DOI: 10.1038/Nrmicro.2016.184  1
2016 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. PMID 27918548 DOI: 10.1038/Nbt.3737  1
2016 Shang X, Scott D, Hodge A, English DR, Giles GG, Ebeling PR, Sanders KM. Dietary protein from different food sources, incident metabolic syndrome and changes in its components: An 11-year longitudinal study in healthy community-dwelling adults. Clinical Nutrition (Edinburgh, Scotland). PMID 27746001 DOI: 10.1016/J.Clnu.2016.09.024  0.36
2016 Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre Ena X, Teater M, Meydan C, Li Z, Poloway D, Wang S, ... ... Scott DW, et al. CREBBP Inactivation Promotes the Development of HDAC3 Dependent Lymphomas. Cancer Discovery. PMID 27733359 DOI: 10.1158/2159-8290.Cd-16-0975  0.32
2016 Shang X, Scott D, Hodge AM, English DR, Giles GG, Ebeling PR, Sanders KM. Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies. The American Journal of Clinical Nutrition. PMID 27629053 DOI: 10.3945/Ajcn.116.140954  0.36
2016 Shang X, Scott D, Hodge A, Khan B, Khan N, English DR, Giles GG, Ebeling PR, Sanders KM. Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults. The International Journal of Cardiovascular Imaging. PMID 27246927 DOI: 10.1007/S10554-016-0920-2  0.36
2016 Gu Z, Lamont GJ, Lamont RJ, Uriarte SM, Wang H, Scott DA. Resolvin D1, resolvin D2 and maresin 1 activate the GSK3β anti-inflammatory axis in TLR4-engaged human monocytes. Innate Immunity. PMID 26878867 DOI: 10.1177/1753425916628618  0.32
2016 Gao S, Li S, Ma Z, Liang S, Shan T, Zhang M, Zhu X, Zhang P, Liu G, Zhou F, Yuan X, Jia R, Potempa J, Scott DA, Lamont RJ, et al. Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer. Infectious Agents and Cancer. 11: 3. PMID 26788120 DOI: 10.1186/S13027-016-0049-X  0.32
2015 Yin H, Zhou H, Kang Y, Zhang X, Duan X, Alnabhan R, Liang S, Scott DA, Lamont RJ, Shang J, Wang H. Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells. Biochimica Et Biophysica Acta. PMID 26708990 DOI: 10.1016/J.Bbagen.2015.12.012  0.32
2015 Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science (New York, N.Y.). PMID 26628643 DOI: 10.1126/Science.Aad5227  0.8
2015 Wang H, Graves MW, Zhou H, Gu Z, Lamont RJ, Scott DA. 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 26613980 DOI: 10.1007/S00011-015-0891-0  0.32
2015 Zhang F, Patel DM, Colavita K, Rodionova I, Buckley B, Scott DA, Kumar A, Shabalina SA, Saha S, Chernov M, Osterman AL, Kashina A. Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase. Nature Communications. 6: 7517. PMID 26175007 DOI: 10.1038/Ncomms8517  0.8
2015 Shang X, Sanders KM, Scott D, Khan B, Hodge A, Khan N, English DR, Giles GG, Ebeling PR. Dietary α-Linolenic Acid and Total ω-3 Fatty Acids Are Inversely Associated with Abdominal Aortic Calcification in Older Women, but Not in Older Men. The Journal of Nutrition. PMID 26041673 DOI: 10.3945/jn.115.211789  0.36
2015 Ramanan V, Shlomai A, Cox DB, Schwartz RE, Michailidis E, Bhatta A, Scott DA, Zhang F, Rice CM, Bhatia SN. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Scientific Reports. 5: 10833. PMID 26035283 DOI: 10.1038/Srep10833  0.8
2015 Zhou Y, Sztukowska M, Wang Q, Inaba H, Potempa J, Scott DA, Wang H, Lamont RJ. Noncanonical Activation of β-Catenin by Porphyromonas gingivalis. Infection and Immunity. 83: 3195-203. PMID 26034209 DOI: 10.1128/Iai.00302-15  0.32
2015 Zhou H, Gao S, Duan X, Liang S, Scott DA, Lamont RJ, Wang H. Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25993992 DOI: 10.1096/Fj.15-270462  0.32
2015 Wang Q, Sztukowska M, Ojo A, Scott DA, Wang H, Lamont RJ. FOXO responses to Porphyromonas gingivalis in epithelial cells. Cellular Microbiology. PMID 25958948 DOI: 10.1111/Cmi.12459  0.32
2015 Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/Nature14299  0.8
2015 Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, et al. Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 27: 354-69. PMID 25759021 DOI: 10.1016/J.Ccell.2015.02.006  0.8
2015 Ratnikov B, Aza-Blanc P, Ronai ZA, Smith JW, Osterman AL, Scott DA. Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma. Oncotarget. 6: 7379-89. PMID 25749035  0.8
2015 Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/J.Cell.2015.02.038  0.8
2015 Viero MP, Moncelsi L, Quadri RF, Béthermin M, Bock J, Burgarella D, Chapman SC, Clements DL, Conley A, Conversi L, Duivenvoorden S, Dunlop JS, Farrah D, Franceschini A, Halpern M, ... ... Scott D, et al. HERMES: CURRENT COSMIC INFRARED BACKGROUND ESTIMATES CAN BE EXPLAINED by KNOWN GALAXIES and THEIR FAINT COMPANIONS at z > 4 Astrophysical Journal Letters. 809. DOI: 10.1088/2041-8205/809/2/L22  0.32
2015 Ma B, Cooray A, Calanog JA, Nayyeri H, Timmons N, Casey C, Baes M, Chapman S, Dannerbauer H, Da Cunha E, De Zotti G, Dunne L, Farrah D, Fu H, Gonzalez-Nuevo J, ... Scott D, et al. Spitzer imaging of strongly lensed Herschel-selected dusty star-forming galaxies Astrophysical Journal. 814. DOI: 10.1088/0004-637X/814/1/17  0.32
2015 Bussmann RS, Riechers D, Fialkov A, Scudder J, Hayward CC, Cowley WI, Bock J, Calanog J, Chapman SC, Cooray A, De Bernardis F, Farrah D, Fu H, Gavazzi R, Hopwood R, ... ... Scott D, et al. HERMES: Alma imaging of herschel-selected dusty star-forming galaxies Astrophysical Journal. 812. DOI: 10.1088/0004-637X/812/1/43  0.32
2014 Wang L, Das U, Scott DA, Tang Y, McLean PJ, Roy S. α-synuclein multimers cluster synaptic vesicles and attenuate recycling. Current Biology : Cb. 24: 2319-26. PMID 25264250 DOI: 10.1016/J.Cub.2014.08.027  0.8
2014 Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889  0.8
2014 Rodionova IA, Schuster BM, Guinn KM, Sorci L, Scott DA, Li X, Kheterpal I, Shoen C, Cynamon M, Locher C, Rubin EJ, Osterman AL. Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria. Mbio. 5. PMID 24549842 DOI: 10.1128/Mbio.00747-13  0.8
2014 Dufort FJ, Gumina MR, Ta NL, Tao Y, Heyse SA, Scott DA, Richardson AD, Seyfried TN, Chiles TC. Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation. The Journal of Biological Chemistry. 289: 7011-24. PMID 24469453 DOI: 10.1074/Jbc.M114.551051  0.8
2014 Sharma V, Nayak J, DeRossi C, Charbono A, Ichikawa M, Ng BG, Grajales-Esquivel E, Srivastava A, Wang L, He P, Scott DA, Russell J, Contreras E, Guess CM, Krajewski S, et al. Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1854-69. PMID 24421398 DOI: 10.1096/fj.13-245514  0.8
2014 Ichikawa M, Scott DA, Losfeld ME, Freeze HH. The metabolic origins of mannose in glycoproteins. The Journal of Biological Chemistry. 289: 6751-61. PMID 24407290 DOI: 10.1074/jbc.M113.544064  0.8
2014 Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.). 343: 84-7. PMID 24336571 DOI: 10.1126/Science.1247005  0.8
2013 Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nature Protocols. 8: 2281-308. PMID 24157548 DOI: 10.1038/Nprot.2013.143  0.8
2013 Tang Y, Scott D, Das U, Gitler D, Ganguly A, Roy S. Fast vesicle transport is required for the slow axonal transport of synapsin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15362-75. PMID 24068803 DOI: 10.1523/Jneurosci.1148-13.2013  0.8
2013 Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154: 1380-9. PMID 23992846 DOI: 10.1016/J.Cell.2013.08.021  0.8
2013 Das U, Scott DA, Ganguly A, Koo EH, Tang Y, Roy S. Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway. Neuron. 79: 447-60. PMID 23931995 DOI: 10.1016/J.Neuron.2013.05.035  0.8
2013 Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/Nature12466  1
2013 Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nature Biotechnology. 31: 827-32. PMID 23873081 DOI: 10.1038/Nbt.2647  0.8
2013 Feng X, Rodriguez-Contreras D, Polley T, Lye LF, Scott D, Burchmore RJ, Beverley SM, Landfear SM. 'Transient' genetic suppression facilitates generation of hexose transporter null mutants in Leishmania mexicana. Molecular Microbiology. 87: 412-29. PMID 23170981 DOI: 10.1111/Mmi.12106  0.8
2012 De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW. Functional specialization in proline biosynthesis of melanoma. Plos One. 7: e45190. PMID 23024808 DOI: 10.1371/Journal.Pone.0045190  0.8
2012 Rodionova IA, Scott DA, Grishin NV, Osterman AL, Rodionov DA. Tagaturonate-fructuronate epimerase UxaE, a novel enzyme in the hexuronate catabolic network in Thermotoga maritima. Environmental Microbiology. 14: 2920-34. PMID 22925190 DOI: 10.1111/J.1462-2920.2012.02856.X  0.8
2012 Filipp FV, Ratnikov B, De Ingeniis J, Smith JW, Osterman AL, Scott DA. Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma Pigment Cell and Melanoma Research. 25: 732-739. PMID 22846158 DOI: 10.1111/pcmr.12000  0.8
2012 Scott D, Roy S. α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10129-35. PMID 22836248 DOI: 10.1523/Jneurosci.0535-12.2012  0.8
2012 Filipp FV, Scott DA, Ronai ZA, Osterman AL, Smith JW. Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells Pigment Cell and Melanoma Research. 25: 375-383. PMID 22360810 DOI: 10.1111/j.1755-148X.2012.00989.x  0.8
2012 Tang Y, Das U, Scott DA, Roy S. The slow axonal transport of alpha-synuclein--mechanistic commonalities amongst diverse cytosolic cargoes. Cytoskeleton (Hoboken, N.J.). 69: 506-13. PMID 22344896 DOI: 10.1002/Cm.21019  0.8
2012 Tang Y, Scott DA, Das U, Edland SD, Radomski K, Koo EH, Roy S. Early and selective impairments in axonal transport kinetics of synaptic cargoes induced by soluble amyloid β-protein oligomers. Traffic (Copenhagen, Denmark). 13: 681-93. PMID 22309053 DOI: 10.1111/J.1600-0854.2012.01340.X  0.8
2012 Schellenberger J, Zielinski DC, Choi W, Madireddi S, Portnoy V, Scott DA, Reed JL, Osterman AL, Palsson B. Predicting outcomes of steady-state ¹³C isotope tracing experiments using Monte Carlo sampling. Bmc Systems Biology. 6: 9. PMID 22289253 DOI: 10.1186/1752-0509-6-9  0.8
2012 Roy S, Yang G, Tang Y, Scott DA. A simple photoactivation and image analysis module for visualizing and analyzing axonal transport with high temporal resolution. Nature Protocols. 7: 62-8. PMID 22179592 DOI: 10.1038/Nprot.2011.428  0.8
2011 Scott DA, Richardson AD, Filipp FV, Knutzen CA, Chiang GG, Ronai ZA, Osterman AL, Smith JW. Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. The Journal of Biological Chemistry. 286: 42626-34. PMID 21998308 DOI: 10.1074/Jbc.M111.282046  0.8
2011 Richardson AD, Scott DA. Reversing the Warburg effect through stromal autophagy. Cell Cycle (Georgetown, Tex.). 10: 2830-1. PMID 21869600 DOI: 10.4161/Cc.10.17.16576  0.8
2011 Scott DA, Das U, Tang Y, Roy S. Mechanistic logic underlying the axonal transport of cytosolic proteins. Neuron. 70: 441-54. PMID 21555071 DOI: 10.1016/J.Neuron.2011.03.022  0.8
2011 Sharma V, Ichikawa M, He P, Scott DA, Bravo Y, Dahl R, Ng BG, Cosford NDP, Freeze HH. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts (The Journal of Biological Chemistry (2011) 286 (39431-39438)) Journal of Biological Chemistry. 286: 43588. DOI: 10.1074/jbc.A111.285502  0.8
2010 Portnoy VA, Scott DA, Lewis NE, Tarasova Y, Osterman AL, Palsson BØ. Deletion of genes encoding cytochrome oxidases and quinol monooxygenase blocks the aerobic-anaerobic shift in Escherichia coli K-12 MG1655. Applied and Environmental Microbiology. 76: 6529-40. PMID 20709841 DOI: 10.1128/Aem.01178-10  0.8
2010 Scott DA, Tabarean I, Tang Y, Cartier A, Masliah E, Roy S. A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8083-95. PMID 20554859 DOI: 10.1523/Jneurosci.1091-10.2010  0.8
2010 Morales MA, Watanabe R, Dacher M, Chafey P, Osorio y Fortéa J, Scott DA, Beverley SM, Ommen G, Clos J, Hem S, Lenormand P, Rousselle JC, Namane A, Späth GF. Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage. Proceedings of the National Academy of Sciences of the United States of America. 107: 8381-6. PMID 20404152 DOI: 10.1073/Pnas.0914768107  0.8
2009 Murta SM, Vickers TJ, Scott DA, Beverley SM. Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major. Molecular Microbiology. 71: 1386-401. PMID 19183277 DOI: 10.1111/J.1365-2958.2009.06610.X  0.8
2008 Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Meijler MM, Janda KD, Ulevitch RJ. Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule. Science (New York, N.Y.). 321: 259-63. PMID 18566250 DOI: 10.1126/Science.1156499  0.8
2008 Lad SP, Yang G, Scott DA, Chao TH, Correia Jda S, de la Torre JC, Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Molecular Immunology. 45: 2277-87. PMID 18207245 DOI: 10.1016/j.molimm.2007.11.018  0.8
2008 Scott DA, Hickerson SM, Vickers TJ, Beverley SM. The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major. The Journal of Biological Chemistry. 283: 155-65. PMID 17981801 DOI: 10.1074/Jbc.M708014200  0.8
2007 Lad SP, Yang G, Scott DA, Wang G, Nair P, Mathison J, Reddy VS, Li E. Chlamydial CT441 Is a PDZ domain-containing tail-specific protease that interferes with the NF-κB pathway of immune response Journal of Bacteriology. 189: 6619-6625. PMID 17631635 DOI: 10.1128/JB.00429-07  0.8
2006 Vickers TJ, Orsomando G, de la Garza RD, Scott DA, Kang SO, Hanson AD, Beverley SM. Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence. The Journal of Biological Chemistry. 281: 38150-8. PMID 17032644 DOI: 10.1074/Jbc.M608387200  0.8
2006 Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Wood MR, Brogan AP, Lehmann M, Mee JM, Iwata K, Pan Q, Fearns C, Knaus UG, Meijler MM, Janda KD, et al. N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways. The Journal of Biological Chemistry. 281: 28822-30. PMID 16893899 DOI: 10.1074/Jbc.M606613200  0.8
2005 Zhang K, Hsu FF, Scott DA, Docampo R, Turk J, Beverley SM. Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. Molecular Microbiology. 55: 1566-78. PMID 15720561 DOI: 10.1111/J.1365-2958.2005.04493.X  0.8
2002 Rodrigues CO, Ruiz FA, Rohloff P, Scott DA, Moreno SNJ. Characterization of isolated acidocalcisomes from Toxoplasma gondii tachyzoites reveals a novel pool of hydrolyzable polyphosphate Journal of Biological Chemistry. 277: 48650-48656. PMID 12379647 DOI: 10.1074/Jbc.M208990200  0.8
2002 Luo S, Scott DA, Docampo R. Trypanosoma cruzi H+-ATPase 1 (TcHA1) and 2 (TcHA2) genes complement yeast mutants defective in H+ pumps and encode plasma membrane P-type H+-ATPases with different enzymatic properties Journal of Biological Chemistry. 277: 44497-44506. PMID 12221074 DOI: 10.1074/Jbc.M202267200  0.8
2002 Martinez R, Wang Y, Benaim G, Benchimol M, De Souza W, Scott DA, Docampo R. A proton pumping pyrophosphatase in the Golgi apparatus and plasma membrane vesicles of Trypanosoma cruzi Molecular and Biochemical Parasitology. 120: 205-213. PMID 11897126 DOI: 10.1016/S0166-6851(01)00456-X  0.8
2002 Rodriguez NM, Docampo R, Lu HG, Scott DA. Overexpression of the Leishmania amazonensis Ca2+-ATPase gene Imaa1 enhances virulence Cellular Microbiology. 4: 117-126. PMID 11896767 DOI: 10.1046/J.1462-5822.2002.00175.X  0.8
2001 Furuya T, Okura M, Ruiz FA, Scott DA, Docampo R. TcSCA Complements Yeast Mutants Defective in Ca2+ Pumps and Encode a Ca2+ -ATPase That Localizes to the Endoplasmic Reticulum of Trypanosoma cruzi Journal of Biological Chemistry. 276: 32437-32445. PMID 11382780 DOI: 10.1074/Jbc.M104000200  0.8
2000 Hill JE, Scott DA, Luo S, Docampo R. Cloning and functional expression of a encoding a vacoular-type proton-translocating pyrophosphatase from Trypanosoma cruzi Biochemical Journal. 351: 281-288. PMID 10998372 DOI: 10.1042/0264-6021:3510281  0.8
2000 Rodrigues CO, Scott DA, Bailey BN, De Souza W, Benchimol M, Moreno B, Urbina JA, Oldfield E, Moreno SN. Vacuolar proton pyrophosphatase activity and pyrophosphate (PPi) in Toxoplasma gondii as possible chemotherapeutic targets. The Biochemical Journal. 349: 737-45. PMID 10903134 DOI: 10.1042/Bj3490737  0.8
2000 Scott DA, Docampo R. Characterization of isolated acidocalcisomes of Trypanosoma cruzi Journal of Biological Chemistry. 275: 24215-24221. PMID 10816577 DOI: 10.1074/Jbc.M002454200  0.8
1999 Urbina JA, Moreno B, Vierkotter S, Oldfield E, Payares G, Sanoja C, Bailey BN, Yan W, Scott DA, Moreno SN, Docampo R. Trypanosoma cruzi contains major pyrophosphate stores, and its growth in vitro and in vivo is blocked by pyrophosphate analogs. The Journal of Biological Chemistry. 274: 33609-15. PMID 10559249 DOI: 10.1074/Jbc.274.47.33609  0.8
1999 Rodrigues CO, Scott DA, Docampo R. Characterization of a vacuolar pyrophosphatase in Trypanosoma brucei and its localization to acidocalcisomes Molecular and Cellular Biology. 19: 7712-7723. PMID 10523660 DOI: 10.1128/Mcb.19.11.7712  0.8
1999 Rodrigues CO, Scott DA, Docampo R. Presence of a vacuolar H+-pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H+-ATPase Biochemical Journal. 340: 759-766. PMID 10359662 DOI: 10.1042/0264-6021:3400759  0.8
1998 Scott DA, De Souza W, Benchimol M, Zhong L, Lu HG, Moreno SNJ, Docampo R. Presence of a plant-like proton-pumping pyrophosphatase in acidocalcisomes of Trypanosoma cruzi Journal of Biological Chemistry. 273: 22151-22158. PMID 9705361 DOI: 10.1074/Jbc.273.34.22151  0.8
1998 Scott DA, Docampo R, Benchimol M. Analysis of the uptake of the fluorescent marker 2',7'- bis-(2-carboxyethyl)-5 (and -6)-carboxyfluorescein (BCECF) by hydrogenosomes in Trichomonas vaginalis European Journal of Cell Biology. 76: 139-145. PMID 9696354 DOI: 10.1016/S0171-9335(98)80027-7  0.8
1998 Scott DA, Docampo R. Two types of H+-ATPase are involved in the acidification of internal compartments in Trypanosoma cruzi Biochemical Journal. 331: 583-589. PMID 9531501 DOI: 10.1042/Bj3310583  0.8
1997 Scott DA, Docampo R, Dvorak JA, Shi S, Leapman RD. In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi. The Journal of Biological Chemistry. 272: 28020-9. PMID 9346954 DOI: 10.1074/Jbc.272.44.28020  0.8
1995 Scott DA, North MJ, Coombs GH. Trichomonas vaginalis: amoeboid and flagellated forms synthesize similar proteinases. Experimental Parasitology. 80: 345-8. PMID 7895847 DOI: 10.1006/expr.1995.1044  0.8
1995 Scott DA, North MJ, Coombs GH. The pathway of secretion of proteinases in Trichomonas vaginalis. International Journal For Parasitology. 25: 657-66. PMID 7657450 DOI: 10.1016/0020-7519(95)99370-X  0.8
1995 Scott DA, Moreno SNJ, Docampo R. Ca2+ storage in Trypanosoma brucei: The influence of cytoplasmic pH and importance of vacuolar acidity Biochemical Journal. 310: 789-794. PMID 7575411 DOI: 10.1042/Bj3100789  0.8
1995 Docampo R, Scott DA, Vercesi AE, Moreno SNJ. Intracellular Ca2+ storage in acidocalcisomes of Trypanosoma cruzi Biochemical Journal. 310: 1005-1012. PMID 7575396 DOI: 10.1042/Bj3101005  0.8
1987 Scott DA, Coombs GH, Sanderson BE. Effects of methotrexate and other antifolates on the growth and dihydrofolate reductase activity of leishmania promastigotes Biochemical Pharmacology. 36: 2043-2045. PMID 3593407 DOI: 10.1016/0006-2952(87)90508-9  0.8
1987 Scott DA, Coombs GH, Sanderson BE. Folate utilisation by Leishmania species and the identification of intracellular derivatives and folate-metabolising enzymes Molecular and Biochemical Parasitology. 23: 139-149. PMID 3574356 DOI: 10.1016/0166-6851(87)90149-6  0.8
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