| Year |
Citation |
Score |
| 2023 |
Kulkarni M, Hardwick JM. Programmed Cell Death in Unicellular Versus Multicellular Organisms. Annual Review of Genetics. PMID 37722687 DOI: 10.1146/annurev-genet-033123-095833 |
0.333 |
|
| 2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Hardwick JM, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.641 |
|
| 2022 |
Stolp ZD, Kulkarni M, Liu Y, Zhu C, Jalisi A, Lin S, Casadevall A, Cunningham KW, Pineda FJ, Teng X, Hardwick JM. Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization. Cell Reports. 39: 110647. PMID 35417721 DOI: 10.1016/j.celrep.2022.110647 |
0.774 |
|
| 2020 |
Sebti S, He C, Pattingre S, Meléndez A, Cuervo AM, Hardwick JM, Griffin DE. Remembering Beth Levine - the autophagy pioneer and woman extraordinaire. The Febs Journal. PMID 32812376 DOI: 10.1111/Febs.15502 |
0.499 |
|
| 2019 |
Lamb HM, Hardwick JM. The Dark Side of Estrogen Stops Translation to Induce Apoptosis. Molecular Cell. 75: 1087-1089. PMID 31539505 DOI: 10.1016/J.Molcel.2019.08.022 |
0.72 |
|
| 2019 |
Teng X, Aouacheria A, Lionnard L, Metz KA, Soane L, Kamiya A, Hardwick JM. KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders. Cns Neuroscience & Therapeutics. 25: 887-902. PMID 31197948 DOI: 10.1111/Cns.13156 |
0.769 |
|
| 2019 |
Teng X, Hardwick JM. Whi2: a new player in amino acid sensing. Current Genetics. PMID 30701278 DOI: 10.1007/S00294-018-00929-9 |
0.781 |
|
| 2019 |
Kulkarni M, Stolp ZD, Hardwick JM. Targeting intrinsic cell death pathways to control fungal pathogens. Biochemical Pharmacology. PMID 30660496 DOI: 10.1016/J.Bcp.2019.01.012 |
0.399 |
|
| 2019 |
Huska JD, Lamb HM, Hardwick JM. Overview of BCL-2 Family Proteins and Therapeutic Potentials. Methods in Molecular Biology (Clifton, N.J.). 1877: 1-21. PMID 30535995 DOI: 10.1007/978-1-4939-8861-7_1 |
0.794 |
|
| 2018 |
Metz KA, Teng X, Coppens I, Lamb HM, Wagner BE, Rosenfeld JA, Chen X, Zhang Y, Kim HJ, Meadow ME, Wang TS, Haberlandt ED, Anderson GW, Leshinsky-Silver E, Bi W, ... ... Hardwick JM, et al. KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect. Annals of Neurology. PMID 30295347 DOI: 10.1002/Ana.25351 |
0.755 |
|
| 2018 |
Teng X, Yau E, Sing C, Hardwick JM. Whi2 signals low amino acid availability to halt yeast growth and cell death. Fems Yeast Research. PMID 30165592 DOI: 10.1093/Femsyr/Foy095 |
0.777 |
|
| 2018 |
Chen X, Wang G, Zhang Y, Dayhoff-Brannigan M, Diny NL, Zhao M, He G, Sing CN, Metz KA, Stolp ZD, Aouacheria A, Cheng WC, Hardwick JM, Teng X. Whi2 is a conserved negative regulator of TORC1 in response to low amino acids. Plos Genetics. 14: e1007592. PMID 30142151 DOI: 10.1371/Journal.Pgen.1007592 |
0.748 |
|
| 2018 |
Hardwick JM. Do Fungi Undergo Apoptosis-Like Programmed Cell Death? Mbio. 9. PMID 30065087 DOI: 10.1128/Mbio.00948-18 |
0.427 |
|
| 2018 |
Aouacheria A, Cunningham KW, Hardwick JM, Palková Z, Powers T, Severin FF, Váchová L. Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death". Science (New York, N.Y.). 360. PMID 29930109 DOI: 10.1126/Science.Aar6910 |
0.428 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Hardwick JM, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.745 |
|
| 2017 |
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, et al. Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell Death and Differentiation. PMID 29229998 DOI: 10.1038/S41418-017-0020-4 |
0.345 |
|
| 2017 |
Aouacheria A, Baghdiguian S, Lamb HM, Huska JD, Pineda FJ, Hardwick JM. Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins. Neurochemistry International. PMID 28461171 DOI: 10.1016/J.Neuint.2017.04.009 |
0.804 |
|
| 2017 |
White K, Arama E, Hardwick JM. Controlling caspase activity in life and death. Plos Genetics. 13: e1006545. PMID 28207784 DOI: 10.1371/Journal.Pgen.1006545 |
0.361 |
|
| 2016 |
Tang HL, Tang HM, Fung MC, Hardwick JM. In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila. Journal of Visualized Experiments : Jove. PMID 27929458 DOI: 10.3791/53992 |
0.434 |
|
| 2016 |
Tang HL, Tang HM, Fung MC, Hardwick JM. Abstract 3495: Tracking reversal of apoptosis after caspase activation in cancer cells Cancer Research. 76: 3495-3495. DOI: 10.1158/1538-7445.Am2016-3495 |
0.464 |
|
| 2015 |
Aouacheria A, Combet C, Tompa P, Hardwick JM. Redefining the BH3 Death Domain as a 'Short Linear Motif'. Trends in Biochemical Sciences. 40: 736-48. PMID 26541461 DOI: 10.1016/J.Tibs.2015.09.007 |
0.427 |
|
| 2015 |
Tang HL, Tang HM, Fung MC, Hardwick JM. In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity. Scientific Reports. 5: 9015. PMID 25757939 DOI: 10.1038/Srep09015 |
0.43 |
|
| 2015 |
Tang HL, Tang HM, Hardwick JM, Fung MC. Strategies for tracking anastasis, a cell survival phenomenon that reverses apoptosis. Journal of Visualized Experiments : Jove. PMID 25742050 DOI: 10.3791/51964 |
0.473 |
|
| 2015 |
Teng X, Hardwick JM. Cell death in genome evolution. Seminars in Cell & Developmental Biology. 39: 3-11. PMID 25725369 DOI: 10.1016/J.Semcdb.2015.02.014 |
0.756 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Hardwick JM, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.732 |
|
| 2014 |
Teng X, Hardwick JM. Genome evolution in yeast reveals connections between rare mutations in human cancers. Microbial Cell (Graz, Austria). 1: 206-209. PMID 28357245 DOI: 10.15698/Mic2014.06.153 |
0.721 |
|
| 2013 |
Teng X, Dayhoff-Brannigan M, Cheng WC, Gilbert CE, Sing CN, Diny NL, Wheelan SJ, Dunham MJ, Boeke JD, Pineda FJ, Hardwick JM. Genome-wide consequences of deleting any single gene. Molecular Cell. 52: 485-94. PMID 24211263 DOI: 10.1016/J.Molcel.2013.09.026 |
0.742 |
|
| 2013 |
Teng X, Hardwick JM. Quantification of genetically controlled cell death in budding yeast. Methods in Molecular Biology (Clifton, N.J.). 1004: 161-70. PMID 23733576 DOI: 10.1007/978-1-62703-383-1_12 |
0.777 |
|
| 2013 |
Hardwick JM, Soane L. Multiple functions of BCL-2 family proteins. Cold Spring Harbor Perspectives in Biology. 5. PMID 23378584 DOI: 10.1101/Cshperspect.A008722 |
0.521 |
|
| 2013 |
Lamb HM, Hardwick JM. Unlatched BAX pairs for death. Cell. 152: 383-4. PMID 23374333 DOI: 10.1016/J.Cell.2013.01.018 |
0.722 |
|
| 2013 |
McNally MA, Soane L, Roelofs BA, Hartman AL, Hardwick JM. The N-terminal helix of Bcl-xL targets mitochondria. Mitochondrion. 13: 119-24. PMID 23333404 DOI: 10.1016/J.Mito.2013.01.004 |
0.799 |
|
| 2013 |
Aouacheria A, Rech de Laval V, Combet C, Hardwick JM. Evolution of Bcl-2 homology motifs: homology versus homoplasy. Trends in Cell Biology. 23: 103-11. PMID 23199982 DOI: 10.1016/J.Tcb.2012.10.010 |
0.413 |
|
| 2012 |
Basañez G, Soane L, Hardwick JM. A new view of the lethal apoptotic pore. Plos Biology. 10: e1001399. PMID 23049484 DOI: 10.1371/Journal.Pbio.1001399 |
0.441 |
|
| 2012 |
Hardwick JM, Chen YB, Jonas EA. Multipolar functions of BCL-2 proteins link energetics to apoptosis. Trends in Cell Biology. 22: 318-28. PMID 22560661 DOI: 10.1016/J.Tcb.2012.03.005 |
0.497 |
|
| 2012 |
Ofengeim D, Chen YB, Miyawaki T, Li H, Sacchetti S, Flannery RJ, Alavian KN, Pontarelli F, Roelofs BA, Hickman JA, Hardwick JM, Zukin RS, Jonas EA. N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nature Neuroscience. 15: 574-80. PMID 22366758 DOI: 10.1038/Nn.3054 |
0.802 |
|
| 2012 |
Mastrangelo AJ, Hardwick JM, Betenbaugh MJ. Bcl-2 inhibits apoptosis and extends recombinant protein production in cells infected with Sindbis viral vectors. Cytotechnology. 22: 169-78. PMID 22358927 DOI: 10.1007/Bf00353936 |
0.414 |
|
| 2011 |
Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, ... ... Hardwick JM, et al. Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. The Journal of Cell Biology. 195: 263-76. PMID 21987637 DOI: 10.1083/Jcb.201108059 |
0.774 |
|
| 2011 |
Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen Y, Messerli SM, Mariggio MA, Rahner C, McNay E, ... ... Hardwick JM, et al. Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nature Cell Biology. 13: 1224-33. PMID 21926988 DOI: 10.1038/Ncb2330 |
0.307 |
|
| 2011 |
Teng X, Cheng WC, Qi B, Yu TX, Ramachandran K, Boersma MD, Hattier T, Lehmann PV, Pineda FJ, Hardwick JM. Gene-dependent cell death in yeast. Cell Death & Disease. 2: e188. PMID 21814286 DOI: 10.1038/Cddis.2011.72 |
0.764 |
|
| 2011 |
Roelofs BA, Hardwick JM. Flying to a halt: Drosophila Aven arrests the cell cycle. Cell Cycle (Georgetown, Tex.). 10: 1350-51. PMID 21487234 DOI: 10.4161/Cc.10.9.15436 |
0.818 |
|
| 2011 |
Abdelwahid E, Rolland S, Teng X, Conradt B, Hardwick JM, White K. Mitochondrial involvement in cell death of non-mammalian eukaryotes. Biochimica Et Biophysica Acta. 1813: 597-607. PMID 20950655 DOI: 10.1016/J.Bbamcr.2010.10.008 |
0.785 |
|
| 2011 |
Alavian KN, Li H, Sacchetti S, Nabili P, Lazrove E, Bonanni L, Smith PJ, Hardwick JM, Jonas EA. Bcl-xL Determines the Metabolic Efficiency of Neurons, through Interaction with Mitochondrial ATP Synthase Biophysical Journal. 100: 459a. DOI: 10.1016/J.Bpj.2010.12.2700 |
0.397 |
|
| 2010 |
Lamb HM, Hardwick JM. Noncanonical functions of BCL-2 proteins in the nervous system Advances in Experimental Medicine and Biology. 687: 115-129. PMID 20919641 DOI: 10.1007/978-1-4419-6706-0_7 |
0.762 |
|
| 2010 |
Teng X, Hardwick JM. The apoptosome at high resolution. Cell. 141: 402-4. PMID 20434981 DOI: 10.1016/J.Cell.2010.04.015 |
0.723 |
|
| 2010 |
Alavian K, Collis L, Li H, Zeng L, Bonanni L, Rahner C, Hardwick JM, Jonas E. BCL-xL Regulates ATP Synthase and Synaptic Efficiency Biophysical Journal. 98: 465a. DOI: 10.1016/J.Bpj.2009.12.2527 |
0.421 |
|
| 2010 |
Hardwick JM. Bcl-2 Proteins regulate mitochondrial dynamics, energetics and neuronal activity Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1797: 140. DOI: 10.1016/J.Bbabio.2010.04.419 |
0.36 |
|
| 2009 |
Hardwick JM, Youle RJ. SnapShot: BCL-2 proteins. Cell. 138: 404, 404.e1. PMID 19632186 DOI: 10.1016/J.Cell.2009.07.003 |
0.51 |
|
| 2009 |
Teng X, Hardwick JM. Reliable method for detection of programmed cell death in yeast. Methods in Molecular Biology (Clifton, N.J.). 559: 335-42. PMID 19609767 DOI: 10.1007/978-1-60327-017-5_23 |
0.774 |
|
| 2009 |
Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, ... ... Hardwick JM, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death and Differentiation. 16: 1093-107. PMID 19373242 DOI: 10.1038/Cdd.2009.44 |
0.59 |
|
| 2009 |
Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM. Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. The Journal of Cell Biology. 184: 707-19. PMID 19255249 DOI: 10.1083/Jcb.200809060 |
0.379 |
|
| 2009 |
Jonas E, Collis L, Li H, Zeng L, Bonanni L, Pypaert M, McNay E, Cline G, Smith P, Hardwick JM. Bcl-xl Regulates ATP Synthase Activity at the Inner Mitochondrial Membrane Biophysical Journal. 96: 538a. DOI: 10.1016/J.Bpj.2008.12.2775 |
0.442 |
|
| 2008 |
Qi B, Hardwick JM. Bcl-2 turns deadly. Nature Chemical Biology. 4: 722-3. PMID 19008882 DOI: 10.1038/Nchembio1208-722 |
0.324 |
|
| 2008 |
Cheng WC, Teng X, Park HK, Tucker CM, Dunham MJ, Hardwick JM. Fis1 deficiency selects for compensatory mutations responsible for cell death and growth control defects. Cell Death and Differentiation. 15: 1838-46. PMID 18756280 DOI: 10.1038/Cdd.2008.117 |
0.766 |
|
| 2008 |
Guo JY, Yamada A, Kajino T, Wu JQ, Tang W, Freel CD, Feng J, Chau BN, Wang MZ, Margolis SS, Yoo HY, Wang XF, Dunphy WG, Irusta PM, Hardwick JM, et al. Aven-dependent activation of ATM following DNA damage. Current Biology : Cb. 18: 933-42. PMID 18571408 DOI: 10.1016/J.Cub.2008.05.045 |
0.321 |
|
| 2008 |
Basañez G, Hardwick JM. Unravelling the bcl-2 apoptosis code with a simple model system. Plos Biology. 6: e154. PMID 18563968 DOI: 10.1371/Journal.Pbio.0060154 |
0.529 |
|
| 2008 |
Cheng WC, Leach KM, Hardwick JM. Mitochondrial death pathways in yeast and mammalian cells. Biochimica Et Biophysica Acta. 1783: 1272-9. PMID 18477482 DOI: 10.1016/J.Bbamcr.2008.04.012 |
0.502 |
|
| 2008 |
Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, ... Hardwick JM, et al. Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 2169-74. PMID 18250306 DOI: 10.1073/Pnas.0711647105 |
0.338 |
|
| 2008 |
Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hardwick JM, Colombini M. Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels. The Journal of Biological Chemistry. 283: 6622-30. PMID 18171672 DOI: 10.1074/Jbc.M706115200 |
0.417 |
|
| 2008 |
Hickman JA, Hardwick JM, Kaczmarek LK, Jonas EA. Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission. Journal of Neurophysiology. 99: 1515-22. PMID 18160428 DOI: 10.1152/Jn.00598.2007 |
0.362 |
|
| 2007 |
Cheng WC, Hardwick JM. A quorum on bacterial programmed cell death. Molecular Cell. 28: 515-7. PMID 18042446 DOI: 10.1016/J.Molcel.2007.11.008 |
0.341 |
|
| 2007 |
Qi B, Hardwick JM. A Bcl-xL timer sets platelet life span. Cell. 128: 1035-6. PMID 17382877 DOI: 10.1016/J.Cell.2007.03.002 |
0.325 |
|
| 2007 |
Figueroa B, Ailor E, Osborne D, Hardwick JM, Reff M, Betenbaugh MJ. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells. Biotechnology and Bioengineering. 97: 877-92. PMID 17099908 DOI: 10.1002/Bit.21222 |
0.363 |
|
| 2006 |
Galonek HL, Hardwick JM. Upgrading the BCL-2 network. Nature Cell Biology. 8: 1317-9. PMID 17139279 DOI: 10.1038/Ncb1206-1317 |
0.456 |
|
| 2006 |
Cheng WC, Berman SB, Ivanovska I, Jonas EA, Lee SJ, Chen Y, Kaczmarek LK, Pineda F, Hardwick JM. Mitochondrial factors with dual roles in death and survival. Oncogene. 25: 4697-705. PMID 16892083 DOI: 10.1038/sj.onc.1209596 |
0.404 |
|
| 2006 |
Chen YB, Seo SY, Kirsch DG, Sheu TT, Cheng WC, Hardwick JM. Alternate functions of viral regulators of cell death. Cell Death and Differentiation. 13: 1318-24. PMID 16741528 DOI: 10.1038/sj.cdd.4401964 |
0.321 |
|
| 2006 |
Sauerwald TM, Figueroa B, Hardwick JM, Oyler GA, Betenbaugh MJ. Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures. Biotechnology and Bioengineering. 94: 362-72. PMID 16598795 DOI: 10.1002/Bit.20874 |
0.444 |
|
| 2005 |
Jonas EA, Hardwick JM, Kaczmarek LK. Actions of BAX on mitochondrial channel activity and on synaptic transmission. Antioxidants & Redox Signaling. 7: 1092-100. PMID 16115013 DOI: 10.1089/Ars.2005.7.1092 |
0.41 |
|
| 2005 |
Ivanovska I, Hardwick JM. Viruses activate a genetically conserved cell death pathway in a unicellular organism. The Journal of Cell Biology. 170: 391-9. PMID 16061692 DOI: 10.1083/Jcb.200503069 |
0.466 |
|
| 2005 |
Polster BM, Basañez G, Etxebarria A, Hardwick JM, Nicholls DG. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. The Journal of Biological Chemistry. 280: 6447-54. PMID 15590628 DOI: 10.1074/Jbc.M413269200 |
0.371 |
|
| 2005 |
Jonas EA, Hickman JA, Hardwick JM, Kaczmarek LK. Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse. The Journal of Biological Chemistry. 280: 4491-7. PMID 15561723 DOI: 10.1074/Jbc.M410661200 |
0.377 |
|
| 2004 |
Hardwick JM, Cheng WC. Mitochondrial programmed cell death pathways in yeast. Developmental Cell. 7: 630-2. PMID 15525523 DOI: 10.1016/J.Devcel.2004.10.013 |
0.448 |
|
| 2004 |
Fannjiang Y, Cheng WC, Lee SJ, Qi B, Pevsner J, McCaffery JM, Hill RB, Basañez G, Hardwick JM. Mitochondrial fission proteins regulate programmed cell death in yeast. Genes & Development. 18: 2785-97. PMID 15520274 DOI: 10.1101/Gad.1247904 |
0.501 |
|
| 2004 |
Jonas EA, Hickman JA, Chachar M, Polster BM, Brandt TA, Fannjiang Y, Ivanovska I, Basañez G, Kinnally KW, Zimmerberg J, Hardwick JM, Kaczmarek LK. Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals. Proceedings of the National Academy of Sciences of the United States of America. 101: 13590-5. PMID 15342906 DOI: 10.1073/Pnas.0401372101 |
0.443 |
|
| 2004 |
Seo SY, Chen YB, Ivanovska I, Ranger AM, Hong SJ, Dawson VL, Korsmeyer SJ, Bellows DS, Fannjiang Y, Hardwick JM. BAD is a pro-survival factor prior to activation of its pro-apoptotic function. The Journal of Biological Chemistry. 279: 42240-9. PMID 15231831 DOI: 10.1074/Jbc.M406775200 |
0.475 |
|
| 2004 |
Irusta PM, Hardwick JM. Neuronal apoptosis pathways in Sindbis virus encephalitis. Progress in Molecular and Subcellular Biology. 36: 71-93. PMID 15171608 DOI: 10.1007/978-3-540-74264-7_5 |
0.408 |
|
| 2004 |
Irusta PM, Lamos E, Galonek HL, Vander Maten MA, Boersma MC, Chen YB, Hardwick JM. Regulation of apoptosis by viruses that infect insects. Archives of Virology. Supplementum. 171-8. PMID 15119772 |
0.31 |
|
| 2004 |
Polster BM, Pevsner J, Hardwick JM. Viral Bcl-2 homologs and their role in virus replication and associated diseases. Biochimica Et Biophysica Acta. 1644: 211-27. PMID 14996505 DOI: 10.1016/J.Bbamcr.2003.11.001 |
0.463 |
|
| 2004 |
Figueroa B, Chen S, Oyler GA, Hardwick JM, Betenbaugh MJ. Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnology and Bioengineering. 85: 589-600. PMID 14966800 DOI: 10.1002/Bit.10913 |
0.454 |
|
| 2004 |
Dohm JA, Lee SJ, Hardwick JM, Hill RB, Gittis AG. Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins. 54: 153-6. PMID 14705031 DOI: 10.1002/Prot.10524 |
0.361 |
|
| 2004 |
Ivanovska I, Galonek HL, Hildeman DA, Hardwick JM. Regulation of cell death in the lymphoid system by Bcl-2 family proteins. Acta Haematologica. 111: 42-55. PMID 14646344 DOI: 10.1159/000074485 |
0.506 |
|
| 2003 |
Irusta PM, Chen YB, Hardwick JM. Viral modulators of cell death provide new links to old pathways. Current Opinion in Cell Biology. 15: 700-5. PMID 14644194 DOI: 10.1016/J.Ceb.2003.10.007 |
0.524 |
|
| 2003 |
Figueroa B, Sauerwald TM, Oyler GA, Hardwick JM, Betenbaugh MJ. A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. Metabolic Engineering. 5: 230-45. PMID 14642351 DOI: 10.1016/S1096-7176(03)00044-2 |
0.36 |
|
| 2003 |
Colón-Ramos DA, Irusta PM, Gan EC, Olson MR, Song J, Morimoto RI, Elliott RM, Lombard M, Hollingsworth R, Hardwick JM, Smith GK, Kornbluth S. Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Molecular Biology of the Cell. 14: 4162-72. PMID 14517326 DOI: 10.1091/Mbc.E03-03-0139 |
0.479 |
|
| 2003 |
Jonas EA, Hoit D, Hickman JA, Brandt TA, Polster BM, Fannjiang Y, McCarthy E, Montanez MK, Hardwick JM, Kaczmarek LK. Modulation of synaptic transmission by the BCL-2 family protein BCL-xL. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8423-31. PMID 12968005 DOI: 10.1523/Jneurosci.23-23-08423.2003 |
0.407 |
|
| 2003 |
Fannjiang Y, Kim CH, Huganir RL, Zou S, Lindsten T, Thompson CB, Mito T, Traystman RJ, Larsen T, Griffin DE, Mandir AS, Dawson TM, Dike S, Sappington AL, Kerr DA, ... ... Hardwick JM, et al. BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Developmental Cell. 4: 575-85. PMID 12689595 DOI: 10.1016/S1534-5807(03)00091-1 |
0.553 |
|
| 2003 |
Hardwick JM, Bellows DS. Viral versus cellular BCL-2 proteins. Cell Death and Differentiation. 10: S68-76. PMID 12655348 DOI: 10.1038/sj.cdd.4401133 |
0.313 |
|
| 2002 |
Hardwick JM, Polster BM. Bax, along with lipid conspirators, allows cytochrome c to escape mitochondria. Molecular Cell. 10: 963-5. PMID 12453403 DOI: 10.1016/S1097-2765(02)00751-7 |
0.357 |
|
| 2002 |
Basañez G, Sharpe JC, Galanis J, Brandt TB, Hardwick JM, Zimmerberg J. Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. The Journal of Biological Chemistry. 277: 49360-5. PMID 12381734 DOI: 10.1074/Jbc.M206069200 |
0.307 |
|
| 2002 |
Kerr DA, Larsen T, Cook SH, Fannjiang YR, Choi E, Griffin DE, Hardwick JM, Irani DN. BCL-2 and BAX protect adult mice from lethal Sindbis virus infection but do not protect spinal cord motor neurons or prevent paralysis. Journal of Virology. 76: 10393-400. PMID 12239316 DOI: 10.1128/Jvi.76.20.10393-10400.2002 |
0.521 |
|
| 2002 |
Ryan CA, Stennicke HR, Nava VE, Burch JB, Hardwick JM, Salvesen GS. Inhibitor specificity of recombinant and endogenous caspase-9. The Biochemical Journal. 366: 595-601. PMID 12067274 DOI: 10.1042/Bj20020863 |
0.427 |
|
| 2002 |
Bellows DS, Howell M, Pearson C, Hazlewood SA, Hardwick JM. Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins. Journal of Virology. 76: 2469-79. PMID 11836425 DOI: 10.1128/Jvi.76.5.2469-2479.2002 |
0.483 |
|
| 2001 |
Biswas RS, Cha HJ, Hardwick JM, Srivastava RK. Inhibition of drug-induced Fas ligand transcription and apoptosis by Bcl-XL. Molecular and Cellular Biochemistry. 225: 7-20. PMID 11716366 DOI: 10.1023/A:1012203110027 |
0.316 |
|
| 2001 |
Basañez G, Zhang J, Chau BN, Maksaev GI, Frolov VA, Brandt TA, Burch J, Hardwick JM, Zimmerberg J. Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes. The Journal of Biological Chemistry. 276: 31083-91. PMID 11399768 DOI: 10.1074/Jbc.M103879200 |
0.339 |
|
| 2001 |
Figueroa B, Sauerwald TM, Mastrangelo AJ, Hardwick JM, Betenbaugh MJ. Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults. Biotechnology and Bioengineering. 73: 211-22. PMID 11257603 DOI: 10.1002/Bit.1053 |
0.453 |
|
| 2001 |
Clem RJ, Sheu TT, Richter BW, He WW, Thornberry NA, Duckett CS, Hardwick JM. c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment. The Journal of Biological Chemistry. 276: 7602-8. PMID 11106668 DOI: 10.1074/Jbc.M010259200 |
0.332 |
|
| 2000 |
Hardwick JM. Cyclin' on the viral path to destruction. Nature Cell Biology. 2: E203-4. PMID 11056549 DOI: 10.1038/35041126 |
0.345 |
|
| 2000 |
Chau BN, Cheng EH, Kerr DA, Hardwick JM. Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1. Molecular Cell. 6: 31-40. PMID 10949025 DOI: 10.1016/S1097-2765(05)00021-3 |
0.454 |
|
| 2000 |
Hardwick JM, Levine B. Sindbis virus vector system for functional analysis of apoptosis regulators. Methods in Enzymology. 322: 492-508. PMID 10914042 DOI: 10.1016/S0076-6879(00)22045-4 |
0.579 |
|
| 2000 |
Bellows DS, Chau BN, Lee P, Lazebnik Y, Burns WH, Hardwick JM. Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins. Journal of Virology. 74: 5024-31. PMID 10799576 DOI: 10.1128/Jvi.74.11.5024-5031.2000 |
0.438 |
|
| 2000 |
Mastrangelo AJ, Hardwick JM, Zou S, Betenbaugh MJ. Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults. Biotechnology and Bioengineering. 67: 555-64. PMID 10649230 DOI: 10.1002/(Sici)1097-0290(20000305)67:5<555::Aid-Bit6>3.0.Co;2-T |
0.414 |
|
| 1999 |
Mastrangelo AJ, Zou S, Hardwick JM, Betenbaugh MJ. Antiapoptosis chemicals prolong productive lifetimes of mammalian cells upon Sindbis virus vector infection. Biotechnology and Bioengineering. 65: 298-305. PMID 10486128 DOI: 10.1002/(Sici)1097-0290(19991105)65:3<298::Aid-Bit7>3.0.Co;2-S |
0.393 |
|
| 1999 |
Srivastava RK, Sasaki CY, Hardwick JM, Longo DL. Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription. The Journal of Experimental Medicine. 190: 253-65. PMID 10432288 DOI: 10.1084/Jem.190.2.253 |
0.396 |
|
| 1999 |
Morrow TA, Muljo SA, Zhang J, Hardwick JM, Schlissel MS. Pro-B-cell-specific transcription and proapoptotic function of protein kinase Ceta. Molecular and Cellular Biology. 19: 5608-18. PMID 10409750 DOI: 10.1128/Mcb.19.8.5608 |
0.396 |
|
| 1999 |
Kirsch DG, Doseff A, Chau BN, Lim DS, de Souza-Pinto NC, Hansford R, Kastan MB, Lazebnik YA, Hardwick JM. Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. The Journal of Biological Chemistry. 274: 21155-61. PMID 10409669 DOI: 10.1074/Jbc.274.30.21155 |
0.324 |
|
| 1999 |
Lewis J, Oyler GA, Ueno K, Fannjiang YR, Chau BN, Vornov J, Korsmeyer SJ, Zou S, Hardwick JM. Inhibition of virus-induced neuronal apoptosis by Bax. Nature Medicine. 5: 832-5. PMID 10395331 DOI: 10.1038/10556 |
0.413 |
|
| 1999 |
Lin KI, Pasinelli P, Brown RH, Hardwick JM, Ratan RR. Decreased intracellular superoxide levels activate Sindbis virus-induced apoptosis. The Journal of Biological Chemistry. 274: 13650-5. PMID 10224137 DOI: 10.1074/Jbc.274.19.13650 |
0.305 |
|
| 1999 |
Griffin DE, Hardwick JM. Perspective: virus infections and the death of neurons. Trends in Microbiology. 7: 155-60. PMID 10217830 DOI: 10.1016/S0966-842X(99)01470-5 |
0.556 |
|
| 1999 |
Srivastava RK, Mi QS, Hardwick JM, Longo DL. Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 3775-80. PMID 10097113 DOI: 10.1073/Pnas.96.7.3775 |
0.369 |
|
| 1998 |
Hardwick JM. Viral interference with apoptosis. Seminars in Cell & Developmental Biology. 9: 339-49. PMID 9665871 DOI: 10.1006/Scdb.1998.0243 |
0.421 |
|
| 1998 |
Clem RJ, Cheng EH, Karp CL, Kirsch DG, Ueno K, Takahashi A, Kastan MB, Griffin DE, Earnshaw WC, Veliuona MA, Hardwick JM. Modulation of cell death by Bcl-XL through caspase interaction. Proceedings of the National Academy of Sciences of the United States of America. 95: 554-9. PMID 9435230 DOI: 10.1073/Pnas.95.2.554 |
0.625 |
|
| 1998 |
Nava VE, Rosen A, Veliuona MA, Clem RJ, Levine B, Hardwick JM. Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway. Journal of Virology. 72: 452-9. PMID 9420245 DOI: 10.1128/Jvi.72.1.452-459.1998 |
0.43 |
|
| 1998 |
Griffin DE, Hardwick JM. Apoptosis in alphavirus encephalitis Seminars in Virology. 8: 481-489. DOI: 10.1006/Smvy.1998.0152 |
0.525 |
|
| 1997 |
Cheng EH, Kirsch DG, Clem RJ, Ravi R, Kastan MB, Bedi A, Ueno K, Hardwick JM. Conversion of Bcl-2 to a Bax-like death effector by caspases. Science (New York, N.Y.). 278: 1966-8. PMID 9395403 DOI: 10.1126/Science.278.5345.1966 |
0.35 |
|
| 1997 |
Griffin DE, Hardwick JM. Regulators of apoptosis on the road to persistent alphavirus infection Annual Review of Microbiology. 51: 565-592. PMID 9343360 DOI: 10.1146/Annurev.Micro.51.1.565 |
0.598 |
|
| 1997 |
Dropulic LK, Hardwick JM, Griffin DE. A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication. Journal of Virology. 71: 6100-5. PMID 9223504 DOI: 10.1128/Jvi.71.8.6100-6105.1997 |
0.436 |
|
| 1997 |
Nava VE, Cheng EH, Veliuona M, Zou S, Clem RJ, Mayer ML, Hardwick JM. Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene. Journal of Virology. 71: 4118-22. PMID 9094693 DOI: 10.1128/Jvi.71.5.4118-4122.1997 |
0.359 |
|
| 1997 |
Cheng EH, Nicholas J, Bellows DS, Hayward GS, Guo HG, Reitz MS, Hardwick JM. A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proceedings of the National Academy of Sciences of the United States of America. 94: 690-4. PMID 9012846 DOI: 10.1073/Pnas.94.2.690 |
0.489 |
|
| 1996 |
Levine B, Goldman JE, Jiang HH, Griffin DE, Hardwick JM. Bc1-2 protects mice against fatal alphavirus encephalitis. Proceedings of the National Academy of Sciences of the United States of America. 93: 4810-5. PMID 8643485 DOI: 10.1073/Pnas.93.10.4810 |
0.649 |
|
| 1996 |
Cheng EH, Levine B, Boise LH, Thompson CB, Hardwick JM. Bax-independent inhibition of apoptosis by Bcl-XL. Nature. 379: 554-6. PMID 8596636 DOI: 10.1038/379554A0 |
0.744 |
|
| 1996 |
Lewis J, Wesselingh SL, Griffin DE, Hardwick JM. Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence. Journal of Virology. 70: 1828-1835. DOI: 10.1128/jvi.70.3.1828-1835.1996 |
0.442 |
|
| 1996 |
Hardwick JM, Oyler GA, Clem RJ. AACR meeting on programmed cell death, Lake George, 19?23 October 1996 Apoptosis. 1: 171-174. DOI: 10.1007/Bf01321099 |
0.383 |
|
| 1996 |
Duckett CS, Nava VE, Gedrich RW, Clem RJ, Van Dongen JL, Gilfillan MC, Shiels H, Hardwick JM, Thompson CB. A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. The Embo Journal. 15: 2685-2694. DOI: 10.1002/J.1460-2075.1996.Tb00629.X |
0.393 |
|
| 1995 |
Esolen LM, Park SW, Hardwick JM, Griffin DE. Apoptosis as a cause of death in measles virus-infected cells. Journal of Virology. 69: 3955-3958. DOI: 10.1128/Jvi.69.6.3955-3958.1995 |
0.487 |
|
| 1994 |
Ubol S, Tucker PC, Griffin DE, Hardwick JM. Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. 91: 5202-6. PMID 8197207 DOI: 10.1073/Pnas.91.11.5202 |
0.494 |
|
| 1994 |
Griffin DE, Levine B, Ubol S, Hardwick JM. The effects of alphavirus infection on neurons Annals of Neurology. 35. PMID 8185292 DOI: 10.1002/Ana.410350709 |
0.645 |
|
| 1994 |
Griffin DE, Levine B, Tyor WR, Tucker PC, Hardwick JM. Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons. Archives of Virology. Supplementum. 9: 31-9. PMID 8032263 DOI: 10.1007/978-3-7091-9326-6_4 |
0.62 |
|
| 1993 |
Levine B, Huang Q, Isaacs JT, Reed JC, Griffin DE, Hardwick JM. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature. 361: 739-42. PMID 8441470 DOI: 10.1038/361739A0 |
0.692 |
|
| 1991 |
Levine B, Hardwick JM, Trapp BD, Crawford TO, Bollinger RC, Griffin DE. Antibody-mediated clearance of alphavirus infection from neurons. Science (New York, N.Y.). 254: 856-60. PMID 1658936 DOI: 10.1126/Science.1658936 |
0.613 |
|
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