| Year |
Citation |
Score |
| 2023 |
Romanuka J, Folkers GE, Gnida M, Kovačič L, Wienk H, Kaptein R, Boelens R. Genetic switching by the Lac repressor is based on two-state Monod-Wyman-Changeux allostery. Proceedings of the National Academy of Sciences of the United States of America. 120: e2311240120. PMID 38019859 DOI: 10.1073/pnas.2311240120 |
0.673 |
|
| 2018 |
Faridounnia M, Folkers GE, Boelens R. Function and Interactions of ERCC1-XPF in DNA Damage Response. Molecules (Basel, Switzerland). 23. PMID 30563071 DOI: 10.3390/Molecules23123205 |
0.536 |
|
| 2016 |
Das D, Faridounnia M, Kovacic L, Kaptein R, Boelens R, Folkers GE. Single-strand DNA Binding by the Helix-Hairpin-Helix Domain of XPF Contributes to Substrate Specificity of ERCC1-XPF. The Journal of Biological Chemistry. PMID 28028171 DOI: 10.1074/Jbc.M116.747857 |
0.753 |
|
| 2016 |
Dongre R, Folkers GE, Gualerzi CO, Boelens R, Wienk H. A model for the interaction of the G3-subdomain of Geobacillus stearothermophilus IF2 with the 30S ribosomal subunit. Protein Science : a Publication of the Protein Society. PMID 27364543 DOI: 10.1002/Pro.2977 |
0.524 |
|
| 2016 |
Dongre R, Folkers G, Gualerzi C, Boelens R, Wienk H. Structure and Dynamics of the Geobacillus stearothermophilus IF2 G3-subdomain Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr25975 |
0.474 |
|
| 2015 |
Faridounnia M, Wienk H, Kovačič L, Folkers GE, Jaspers NG, Kaptein R, Hoeijmakers JH, Boelens R. The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex. The Journal of Biological Chemistry. 290: 20541-55. PMID 26085086 DOI: 10.1074/Jbc.M114.635169 |
0.629 |
|
| 2014 |
Khan F, Daniëls MA, Folkers GE, Boelens R, Saqlan Naqvi SM, van Ingen H. Structural basis of nucleic acid binding by Nicotiana tabacum glycine-rich RNA-binding protein: implications for its RNA chaperone function. Nucleic Acids Research. 42: 8705-18. PMID 24957607 DOI: 10.1093/Nar/Gku468 |
0.577 |
|
| 2014 |
Kastritis PL, Rodrigues JP, Folkers GE, Boelens R, Bonvin AM. Proteins feel more than they see: fine-tuning of binding affinity by properties of the non-interacting surface. Journal of Molecular Biology. 426: 2632-52. PMID 24768922 DOI: 10.1016/J.Jmb.2014.04.017 |
0.543 |
|
| 2013 |
Wienk H, Slootweg JC, Speerstra S, Kaptein R, Boelens R, Folkers GE. The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition. Nucleic Acids Research. 41: 6739-49. PMID 23661679 DOI: 10.1093/Nar/Gkt354 |
0.728 |
|
| 2012 |
Das D, Folkers GE, van Dijk M, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R. The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition. Structure (London, England : 1993). 20: 667-75. PMID 22483113 DOI: 10.1016/J.Str.2012.02.009 |
0.766 |
|
| 2012 |
Wienk H, Tishchenko E, Belardinelli R, Tomaselli S, Dongre R, Spurio R, Folkers GE, Gualerzi CO, Boelens R. Structural dynamics of bacterial translation initiation factor IF2. The Journal of Biological Chemistry. 287: 10922-32. PMID 22308033 DOI: 10.1074/Jbc.M111.333393 |
0.55 |
|
| 2011 |
Berger I, Blanco AG, Boelens R, Cavarelli J, Coll M, Folkers GE, Nie Y, Pogenberg V, Schultz P, Wilmanns M, Moras D, Poterszman A. Structural insights into transcription complexes. Journal of Structural Biology. 175: 135-46. PMID 21571073 DOI: 10.1016/J.Jsb.2011.04.015 |
0.516 |
|
| 2010 |
Huang A, de Jong RN, Folkers GE, Boelens R. NMR characterization of foldedness for the production of E3 RING domains. Journal of Structural Biology. 172: 120-7. PMID 20682345 DOI: 10.1016/J.Jsb.2010.07.014 |
0.539 |
|
| 2010 |
Bird LE, Ren J, Nettleship JE, Folkers GE, Owens RJ, Stammers DK. Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains. Bmc Structural Biology. 10: 13. PMID 20509910 DOI: 10.1186/1472-6807-10-13 |
0.353 |
|
| 2009 |
Romanuka J, van den Bulke H, Kaptein R, Boelens R, Folkers GE. Novel strategies to overcome expression problems encountered with toxic proteins: application to the production of Lac repressor proteins for NMR studies. Protein Expression and Purification. 67: 104-12. PMID 19460439 DOI: 10.1016/J.Pep.2009.05.008 |
0.619 |
|
| 2009 |
Romanuka J, Folkers GE, Biris N, Tishchenko E, Wienk H, Bonvin AM, Kaptein R, Boelens R. Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. Journal of Molecular Biology. 390: 478-89. PMID 19450607 DOI: 10.1016/J.Jmb.2009.05.022 |
0.608 |
|
| 2009 |
Wienk H, Lammers I, Hotze A, Wu J, Wechselberger RW, Owens R, Stammers DK, Stuart D, Kaptein R, Folkers GE. The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension. Biochemistry. 48: 4431-9. PMID 19348505 DOI: 10.1021/bi9001997 |
0.573 |
|
| 2008 |
Diercks T, AB E, Daniels MA, de Jong RN, Besseling R, Kaptein R, Folkers GE. Solution structure and characterization of the DNA-binding activity of the B3BP-Smr domain. Journal of Molecular Biology. 383: 1156-70. PMID 18804481 DOI: 10.1016/j.jmb.2008.09.005 |
0.676 |
|
| 2008 |
de Jong RN, Truffault V, Diercks T, Ab E, Daniels MA, Kaptein R, Folkers GE. Structure and DNA binding of the human Rtf1 Plus3 domain. Structure (London, England : 1993). 16: 149-59. PMID 18184592 DOI: 10.1016/j.str.2007.10.018 |
0.632 |
|
| 2008 |
Das D, Tripsianes K, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R, Folkers GE. The HhH domain of the human DNA repair protein XPF forms stable homodimers. Proteins. 70: 1551-63. PMID 17912758 DOI: 10.1002/Prot.21635 |
0.745 |
|
| 2007 |
Tripsianes K, Folkers GE, Zheng C, Das D, Grinstead JS, Kaptein R, Boelens R. Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization. Nucleic Acids Research. 35: 5789-98. PMID 17720715 DOI: 10.1093/Nar/Gkm503 |
0.758 |
|
| 2007 |
Kamphuis MB, Monti MC, van den Heuvel RH, Santos-Sierra S, Folkers GE, Lemonnier M, DÃaz-Orejas R, Heck AJ, Boelens R. Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE. Proteins. 67: 219-31. PMID 17206710 DOI: 10.1002/Prot.21254 |
0.53 |
|
| 2007 |
Tripsianes K, Folkers G, Zheng C, Das D, Grinstead J, Kaptein R, Boelens R. Solution structure of the ERCC1 central domain Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jpd/Pdb |
0.691 |
|
| 2006 |
de Jong RN, Daniëls MA, Kaptein R, Folkers GE. Enzyme free cloning for high throughput gene cloning and expression. Journal of Structural and Functional Genomics. 7: 109-18. PMID 17295099 DOI: 10.1007/s10969-006-9014-z |
0.374 |
|
| 2006 |
Au K, Berrow NS, Blagova E, Boucher IW, Boyle MP, Brannigan JA, Carter LG, Dierks T, Folkers G, Grenha R, Harlos K, Kaptein R, Kalliomaa AK, Levdikov VM, Meier C, et al. Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis. Acta Crystallographica. Section D, Biological Crystallography. 62: 1267-75. PMID 17001104 DOI: 10.1107/S0907444906033555 |
0.502 |
|
| 2006 |
Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dötsch V, Engelke F, Folkers GE, Griesinger C, Gronwald W, Günther U, Habeck M, de Jong RN, et al. NMR in the SPINE Structural Proteomics project. Acta Crystallographica. Section D, Biological Crystallography. 62: 1150-61. PMID 17001092 DOI: 10.1107/S0907444906032070 |
0.469 |
|
| 2006 |
Grenha R, Rzechorzek NJ, Brannigan JA, de Jong RN, Ab E, Diercks T, Truffault V, Ladds JC, Fogg MJ, Bongiorni C, Perego M, Kaptein R, Wilson KS, Folkers GE, Wilkinson AJ. Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli. The Journal of Biological Chemistry. 281: 37993-8003. PMID 17001075 DOI: 10.1074/jbc.M607617200 |
0.486 |
|
| 2006 |
Milon P, Tischenko E, Tomsic J, Caserta E, Folkers G, La Teana A, Rodnina MV, Pon CL, Boelens R, Gualerzi CO. The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor. Proceedings of the National Academy of Sciences of the United States of America. 103: 13962-7. PMID 16968770 DOI: 10.1073/Pnas.0606384103 |
0.554 |
|
| 2006 |
Jonker HR, Wechselberger RW, Pinkse M, Kaptein R, Folkers GE. Gradual phosphorylation regulates PC4 coactivator function. The Febs Journal. 273: 1430-44. PMID 16689930 DOI: 10.1111/j.1742-4658.2006.05165.x |
0.508 |
|
| 2006 |
Jonker HR, Wechselberger RW, Boelens R, Kaptein R, Folkers GE. The intrinsically unstructured domain of PC4 modulates the activity of the structured core through inter- and intramolecular interactions. Biochemistry. 45: 5067-81. PMID 16605275 DOI: 10.1021/Bi052531B |
0.738 |
|
| 2006 |
Limacher A, Kloer DP, Flückiger S, Folkers G, Crameri R, Scapozza L. The crystal structure of Aspergillus fumigatus cyclophilin reveals 3D domain swapping of a central element Structure. 14: 185-195. PMID 16472738 DOI: 10.1016/J.Str.2005.10.015 |
0.374 |
|
| 2006 |
de Jong RN, Ab E, Diercks T, Truffault V, Daniëls M, Kaptein R, Folkers GE. Solution structure of the human ubiquitin-specific protease 15 DUSP domain. The Journal of Biological Chemistry. 281: 5026-31. PMID 16298993 DOI: 10.1074/jbc.M510993200 |
0.575 |
|
| 2006 |
Grenha R, Rzechorzek NJ, Brannigan JA, Ab E, Folkers GE, Jong RND, Diercks T, Wilkinson AJ, Kaptein R, Wilson KS. Nmr Solution Structure Of A Protein Aspartic Acid Phosphate Phosphatase From Bacillus Anthracis Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr7349 |
0.458 |
|
| 2005 |
Tripsianes K, Folkers G, Ab E, Das D, Odijk H, Jaspers NG, Hoeijmakers JH, Kaptein R, Boelens R. The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair. Structure (London, England : 1993). 13: 1849-58. PMID 16338413 DOI: 10.1016/J.Str.2005.08.014 |
0.769 |
|
| 2005 |
Kopke Salinas R, Folkers GE, Bonvin AM, Das D, Boelens R, Kaptein R. Altered specificity in DNA binding by the lac repressor: a mutant lac headpiece that mimics the gal repressor. Chembiochem : a European Journal of Chemical Biology. 6: 1628-37. PMID 16094693 DOI: 10.1002/Cbic.200500049 |
0.717 |
|
| 2005 |
Patterson HM, Brannigan JA, Cutting SM, Wilson KS, Wilkinson AJ, Ab E, Diercks T, de Jong RN, Truffault V, Folkers GE, Kaptein R. The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus. The Journal of Biological Chemistry. 280: 36214-20. PMID 16049010 DOI: 10.1074/jbc.M506910200 |
0.514 |
|
| 2005 |
Jonker HR, Wechselberger RW, Boelens R, Folkers GE, Kaptein R. Structural properties of the promiscuous VP16 activation domain. Biochemistry. 44: 827-39. PMID 15654739 DOI: 10.1021/Bi0482912 |
0.673 |
|
| 2004 |
Perozzo R, Folkers G, Scapozza L. Thermodynamics of protein-ligand interactions: History, presence, and future aspects Journal of Receptors and Signal Transduction. 24: 1-52. PMID 15344878 DOI: 10.1081/Rrs-120037896 |
0.3 |
|
| 2004 |
Folkers GE, van Buuren BN, Kaptein R. Expression screening, protein purification and NMR analysis of human protein domains for structural genomics. Journal of Structural and Functional Genomics. 5: 119-31. PMID 15263851 DOI: 10.1023/B:JSFG.0000029200.66197.0c |
0.493 |
|
| 2004 |
Cavalli A, Prota AE, Stehle T, Dermody TS, Recanatini M, Folkers G, Scapozza L. A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure. Biophysical Journal. 86: 3423-31. PMID 15189844 DOI: 10.1529/Biophysj.103.030825 |
0.347 |
|
| 2002 |
Singh S, Folkers GE, Bonvin AM, Boelens R, Wechselberger R, Niztayev A, Kaptein R. Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli. The Embo Journal. 21: 6257-66. PMID 12426397 DOI: 10.1093/Emboj/Cdf627 |
0.736 |
|
| 2001 |
Kalodimos CG, Folkers GE, Boelens R, Kaptein R. Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices. Proceedings of the National Academy of Sciences of the United States of America. 98: 6039-44. PMID 11353825 DOI: 10.1073/Pnas.101129898 |
0.696 |
|
| 2000 |
Nooren IM, Folkers GE, Kaptein R, Sauer RT, Boelens R. Structure and dynamics of the tetrameric mnt repressor and a model for its DNA complex. Journal of Biomolecular Structure & Dynamics. 17: 113-22. PMID 22607414 DOI: 10.1080/07391102.2000.10506611 |
0.73 |
|
| 2000 |
van Tilborg PJ, Czisch M, Mulder FA, Folkers GE, Bonvin AM, Nair M, Boelens R, Kaptein R. Changes in dynamical behavior of the retinoid X receptor DNA-binding domain upon binding to a 14 base-pair DNA half site. Biochemistry. 39: 8747-57. PMID 10913286 DOI: 10.1021/Bi991550G |
0.69 |
|
| 1999 |
Spronk CA, Folkers GE, Noordman AM, Wechselberger R, van den Brink N, Boelens R, Kaptein R. Hinge-helix formation and DNA bending in various lac repressor-operator complexes. The Embo Journal. 18: 6472-80. PMID 10562559 DOI: 10.1093/Emboj/18.22.6472 |
0.652 |
|
| 1999 |
van Tilborg PJ, Mulder FA, de Backer MM, Nair M, van Heerde EC, Folkers G, van der Saag PT, Karimi-Nejad Y, Boelens R, Kaptein R. Millisecond to microsecond time scale dynamics of the retinoid X and retinoic acid receptor DNA-binding domains and dimeric complex formation. Biochemistry. 38: 1951-6. PMID 10026278 DOI: 10.1021/Bi982526Q |
0.708 |
|
| 1995 |
Kern P, Brunne RM, Folkers G. Nucleotide-binding properties of adenylate kinase from Escherichia coli: a molecular dynamics study in aqueous and vacuum environments. Journal of Computer-Aided Molecular Design. 8: 367-88. PMID 7815090 DOI: 10.1007/Bf00125373 |
0.335 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2000 |
Perozzo R, Jelesarov I, Bosshard HR, Folkers G, Scapozza L. Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase: A calorimetric study Journal of Biological Chemistry. 275: 16139-16145. PMID 10747922 DOI: 10.1074/Jbc.M000509200 |
0.296 |
|
| 1993 |
Folkers GE, van der Leede BJ, van der Saag PT. The retinoic acid receptor-beta 2 contains two separate cell-specific transactivation domains, at the N-terminus and in the ligand-binding domain. Molecular Endocrinology (Baltimore, Md.). 7: 616-27. PMID 8389001 DOI: 10.1210/MEND.7.4.8389001 |
0.293 |
|
| 2002 |
Lerch M, Gafner V, Bader R, Christen B, Folkers G, Zerbe O. Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles. Journal of Molecular Biology. 322: 1117-33. PMID 12367532 DOI: 10.1016/S0022-2836(02)00889-6 |
0.292 |
|
| 1992 |
Folkers G, Trumpp-Kallmeyer S, Gutbrod O, Krickl S, Fetzer J, Keil GM. Computer-aided active-site-directed modeling of the herpes simplex virus 1 and human thymidine kinase. Journal of Computer-Aided Molecular Design. 5: 385-404. PMID 1663155 DOI: 10.1007/Bf00125660 |
0.285 |
|
| 2016 |
Kaplan M, Narasimhan S, de Heus C, Mance D, van Doorn S, Houben K, Popov-Čeleketić D, Damman R, Katrukha EA, Jain P, Geerts WJ, Heck AJ, Folkers GE, Kapitein LC, Lemeer S, et al. EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR. Cell. PMID 27839865 DOI: 10.1016/J.Cell.2016.10.038 |
0.283 |
|
| 2001 |
Wurth C, Kessler U, Vogt J, Schulz GE, Folkers G, Scapozza L. The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase Protein Science. 10: 63-73. PMID 11266595 DOI: 10.1110/Ps.27401 |
0.282 |
|
| 1997 |
Folkers G, Alber F, Amrhein I, Behrends H, Bohner T, Gerber S, Kuonen O, Scapozza L. Integrated homology modelling and X-ray study of herpes simplex virus I thymidine kinase: a case study. Journal of Receptor and Signal Transduction Research. 17: 475-94. PMID 9029509 DOI: 10.3109/10799899709036622 |
0.28 |
|
| 1996 |
Folkers GE, Van der Burg B, Van der Saag PT. A role for cofactors in synergistic and cell-specific activation by retinoic acid receptors and retinoid X receptor. The Journal of Steroid Biochemistry and Molecular Biology. 56: 119-29. PMID 8603032 DOI: 10.1016/0960-0760(95)00229-4 |
0.271 |
|
| 1996 |
Kern P, Brunne RM, Rognan D, Folkers G. A pseudo-particle approach for studying protein-ligand models truncated to their active sites. Biopolymers. 38: 619-37. PMID 8722231 DOI: 10.1002/(Sici)1097-0282(199605)38:5<619::Aid-Bip7>3.0.Co;2-V |
0.271 |
|
| 2009 |
SIEMION IZ, FOLKERS G, SZEWCZUK Z, JANKOWSKI A, KUBIK A, VOELTER W. Peptides related to the active fragment of “proline rich polypeptide”, an immunoregulatory protein of the ovine colostrums International Journal of Peptide and Protein Research. 36: 506-514. DOI: 10.1111/J.1399-3011.1990.Tb00989.X |
0.268 |
|
| 1993 |
Folkers G, Brünjes J, Michael M, Schill J. Modelling by homology of the HSV1-TK sequence embedded structural alignment. Journal of Receptor Research. 13: 147-62. PMID 8383749 DOI: 10.3109/10799899309073652 |
0.268 |
|
| 2001 |
Rognan D, Mukhija S, Folkers G, Zerbe O. NMR-restrained docking of a peptidic inhibitor to the N-terminal domain of the phosphoenolpyruvate: Sugar phosphotransferase enzyme I Journal of Computer-Aided Molecular Design. 15: 103-115. PMID 11272698 DOI: 10.1023/A:1008145813315 |
0.266 |
|
| 1992 |
van der Leede BJ, Folkers GE, Kruyt FA, van der Saag PT. Genomic organization of the human retinoic acid receptor beta 2. Biochemical and Biophysical Research Communications. 188: 695-702. PMID 1332705 DOI: 10.1016/0006-291X(92)91112-4 |
0.265 |
|
| 2002 |
Flückiger S, Scapozza L, Mayer C, Blaser K, Folkers G, Crameri R. Immunological and structural analysis of IgE-mediated cross-reactivity between manganese superoxide dismutases. International Archives of Allergy and Immunology. 128: 292-303. PMID 12218367 DOI: 10.1159/000063862 |
0.259 |
|
| 2005 |
Birringer MS, Claus MT, Folkers G, Kloer DP, Schulz GE, Scapozza L. Structure of a type II thymidine kinase with bound dTTP Febs Letters. 579: 1376-1382. PMID 15733844 DOI: 10.1016/J.Febslet.2005.01.034 |
0.259 |
|
| 1995 |
Folkers GE, van der Saag PT. Adenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR beta. Molecular and Cellular Biology. 15: 5868-78. PMID 7565739 DOI: 10.1128/MCB.15.11.5868 |
0.258 |
|
| 1998 |
Kussmann-Gerber S, Kuonen O, Folkers G, Pilger BD, Scapozza L. Drug resistance of herpes simplex virus type 1--structural considerations at the molecular level of the thymidine kinase. European Journal of Biochemistry. 255: 472-81. PMID 9716390 DOI: 10.1046/J.1432-1327.1998.2550472.X |
0.257 |
|
| 2009 |
Dadvar P, Kovanich D, Folkers GE, Rumpel K, Raijmakers R, Heck AJR. Cover Picture: Phosphatidylethanolamine-Binding Proteins, Including RKIP, Exhibit Affinity for Phosphodiesterase-5 Inhibitors (ChemBioChem 16/2009) Chembiochem. 10: 2545-2545. DOI: 10.1002/Cbic.200990071 |
0.257 |
|
| 2015 |
Kaplan M, Cukkemane A, van Zundert GC, Narasimhan S, Daniëls M, Mance D, Waksman G, Bonvin AM, Fronzes R, Folkers GE, Baldus M. Probing a cell-embedded megadalton protein complex by DNP-supported solid-state NMR. Nature Methods. PMID 25984698 DOI: 10.1038/Nmeth.3406 |
0.256 |
|
| 2009 |
Dadvar P, Kovanich D, Folkers GE, Rumpel K, Raijmakers R, Heck AJR. Phosphatidylethanolamine-binding proteins, including RKIP, exhibit affinity for phosphodiesterase-5 inhibitors Chembiochem. 10: 2654-2662. PMID 19760692 DOI: 10.1002/Cbic.200900452 |
0.255 |
|
| 2006 |
Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, et al. Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE. Acta Crystallographica. Section D, Biological Crystallography. 62: 1103-13. PMID 17001088 DOI: 10.1107/S0907444906029775 |
0.252 |
|
| 2021 |
le Paige UB, Xiang S, Hendrix MMRM, Zhang Y, Folkers GE, Weingarth M, Bonvin AMJJ, Kutateladze TG, Voets IK, Baldus M, van Ingen H. Characterization of nucleosome sediments for protein interaction studies by solid-state NMR spectroscopy Magnetic Resonance. 2: 187-202. DOI: 10.5194/MR-2-187-2021 |
0.251 |
|
| 2021 |
le Paige UB, Xiang S, Hendrix MMRM, Zhang Y, Folkers GE, Weingarth M, Bonvin AMJJ, Kutateladze TG, Voets IK, Baldus M, van Ingen H. Characterization of nucleosome sediments for protein interaction studies by solid-state NMR spectroscopy. Magnetic Resonance (Gottingen, Germany). 2: 187-202. PMID 35647606 DOI: 10.5194/mr-2-187-2021 |
0.251 |
|
| 1998 |
Krebs S, Lamas JR, Poenaru S, Folkers G, de Castro JA, Seebach D, Rognan D. Substituting nonpeptidic spacers for the T cell receptor-binding part of class I major histocompatibility complex-binding peptides. The Journal of Biological Chemistry. 273: 19072-9. PMID 9668090 DOI: 10.1074/Jbc.273.30.19072 |
0.25 |
|
| 2000 |
Vogt J, Perozzo R, Pautsch A, Prota A, Schelling P, Pilger B, Folkers G, Scapozza L, Schulz GE. Nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography Proteins: Structure, Function and Genetics. 41: 545-553. PMID 11056041 DOI: 10.1002/1097-0134(20001201)41:4<545::Aid-Prot110>3.0.Co;2-8 |
0.248 |
|
| 2005 |
Scapozza L, Rognan D, Folkers G, Daser A. Molecular dynamics and structure-based drug design for predicting non-natural nonapeptide binding to a class I MHC protein. Acta Crystallographica. Section D, Biological Crystallography. 51: 541-9. PMID 15299842 DOI: 10.1107/S0907444995002678 |
0.245 |
|
| 2005 |
Kostrewa D, Winkler FK, Folkers G, Scapozza L, Perozzo R. The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum. Protein Science : a Publication of the Protein Society. 14: 1570-80. PMID 15930004 DOI: 10.1110/Ps.051373005 |
0.244 |
|
| 1999 |
Dédier S, Krebs S, Lamas JR, Poenaru S, Folkers G, López de Castro JA, Seebach D, Rognan D. Structure-based design of nonnatural ligands for the HLA-B27 protein. Journal of Receptor and Signal Transduction Research. 19: 645-57. PMID 10071790 DOI: 10.3109/10799899909036677 |
0.244 |
|
| 1995 |
Greenidge PA, Merz A, Folkers G. A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites. Journal of Computer-Aided Molecular Design. 9: 473-8. PMID 8789189 DOI: 10.1007/Bf00124318 |
0.241 |
|
| 1992 |
Kruyt FAE, Folkers G, Brink CEvd, Saag PTvd. A Cyclic-Amp Response Element Is Involved In Retinoic Acid-Dependent Rar-Beta-2 Promoter Activation Nucleic Acids Research. 20: 6393-6399. PMID 1335571 DOI: 10.1093/Nar/20.23.6393 |
0.241 |
|
| 1992 |
Rognan D, Zimmermann N, Jung G, Folkers G. Molecular dynamics study of a complex between the human histocompatibility antigen HLA-A2 and the IMP58-66 nonapeptide from influenza virus matrix protein. European Journal of Biochemistry. 208: 101-13. PMID 1511679 DOI: 10.1111/J.1432-1033.1992.Tb17163.X |
0.238 |
|
| 2019 |
Narasimhan S, Scherpe S, Lucini Paioni A, van der Zwan J, Folkers GE, Ovaa H, Baldus M. DNP supported solid-state NMR of proteins inside Mammalian Cells. Angewandte Chemie (International Ed. in English). PMID 31233270 DOI: 10.1002/anie.201903246 |
0.236 |
|
| 2014 |
Pliska V, Folkers G, Spiwok V. Thermodynamics of the interaction between oxytocin and its myometrial receptor in sheep: A stepwise binding mechanism Biochemical Pharmacology. 91: 119-127. PMID 25010721 DOI: 10.1016/J.Bcp.2014.06.025 |
0.231 |
|
| 1994 |
Rognan D, Scapozza L, Folkers G, Daser A. Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes. Biochemistry. 33: 11476-85. PMID 7522551 DOI: 10.1021/Bi00204A009 |
0.231 |
|
| 2001 |
Sulpizi M, Schelling P, Folkers G, Carloni P, Scapozza L. The rational of catalytic activity of herpes simplex virus thymidine kinase. A combined biochemical and quantum chemical study Journal of Biological Chemistry. 276: 21692-21697. PMID 11262392 DOI: 10.1074/Jbc.M010223200 |
0.229 |
|
| 1998 |
Seebach D, Poenaru S, Folkers G, Rognan D. Synthesis of Oligo(3-hydroxybutanoate)(OHB)-Containing Peptides with High Binding Affinity to a Class-I-MHC Protein Helvetica Chimica Acta. 81: 1181-1200. DOI: 10.1002/Hlca.19980810529 |
0.228 |
|
| 2007 |
Patterson H, Brannigan J, Cutting S, Wilson K, Wilkinson A, Ab E, Diercks T, Folkers G, Jong Rd, Truffault V. Backbone 1H, 13C, and 15N Chemical Shift Assignments for BOFC Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr6731 |
0.224 |
|
| 1992 |
Rognan D, Reddehase MJ, Koszinowski UH, Folkers G. Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein. Proteins. 13: 70-85. PMID 1594579 DOI: 10.1002/Prot.340130107 |
0.22 |
|
| 2002 |
Pospisil P, Pilger BD, Marveggio S, Schelling P, Wurth C, Scapozza L, Folkers G, Pongracic M, Mintas M, Malic SR. Synthesis, kinetics, and molecular docking of novel 9-(2-hydroxypropyl)purine nucleoside analogs as ligands of herpesviral thymidine kinases Helvetica Chimica Acta. 85: 3237-3250. DOI: 10.1002/1522-2675(200210)85:10<3237::Aid-Hlca3237>3.0.Co;2-3 |
0.22 |
|
| 1998 |
Zbinden P, Dobler M, Folkers G, Vedani A. PrGen: Pseudoreceptor Modeling Using Receptor‐mediated Ligand Alignment and Pharmacophore Equilibration Quantitative Structure-Activity Relationships. 17: 122-130. DOI: 10.1002/(Sici)1521-3838(199804)17:02<122::Aid-Qsar122>3.3.Co;2-C |
0.218 |
|
| 1999 |
Krebs S, Folkers G, Rognan D. Binding of rationally designed non-natural peptides to the human leukocyte antigen HLA-B*2705. Journal of Peptide Science : An Official Publication of the European Peptide Society. 4: 378-88. PMID 9796857 DOI: 10.1002/(Sici)1099-1387(199809)4:6<378::Aid-Psc157>3.0.Co;2-B |
0.218 |
|
| 2002 |
Pospisil P, Kuoni T, Scapozza L, Folkers G. Methodology and problems of protein-ligand docking: case study of dihydroorotate dehydrogenase, thymidine kinase, and phosphodiesterase 4. Journal of Receptor and Signal Transduction Research. 22: 141-54. PMID 12503612 DOI: 10.1081/Rrs-120014592 |
0.218 |
|
| 2001 |
Demuth C, Zerbe O, Rognan D, Söll R, Beck-Sickinger A, Folkers G, Spichiger UE. A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions Biosensors and Bioelectronics. 16: 783-789. PMID 11679256 DOI: 10.1016/S0956-5663(01)00221-4 |
0.217 |
|
| 2000 |
Zhou X, Alber F, Folkers G, Gonnet GH, Chelvanayagam G. An analysis of the helix-to-strand transition between peptides with identical sequence Proteins: Structure, Function and Genetics. 41: 248-256. PMID 10966577 DOI: 10.1002/1097-0134(20001101)41:2<248::Aid-Prot90>3.0.Co;2-J |
0.216 |
|
| 2020 |
Narasimhan S, Folkers GE, Baldus M. When Small becomes Too Big: Expanding the Use of In-Cell Solid-State NMR Spectroscopy. Chempluschem. 85: 760-768. PMID 32297474 DOI: 10.1002/Cplu.202000167 |
0.215 |
|
| 1998 |
Alber F, Kuonen O, Scapozza L, Folkers G, Carloni P. Density functional studies on herpes simplex virus type 1 thymidine kinase-substrate interactions: the role of Tyr-172 and Met-128 in thymine fixation. Proteins. 31: 453-9. PMID 9626704 DOI: 10.1002/(Sici)1097-0134(19980601)31:4<453::Aid-Prot11>3.0.Co;2-E |
0.215 |
|
| 2005 |
Lerch M, Kamimori H, Folkers G, Aguilar MI, Beck-Sickinger AG, Zerbe O. Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding Biochemistry. 44: 9255-9264. PMID 15966750 DOI: 10.1021/Bi0501232 |
0.213 |
|
| 2004 |
Folkers G. Pharmaceutical Chemistry at the ETH Zürich Chimia. 58: 707-710. DOI: 10.2533/000942904777677362 |
0.212 |
|
| 1999 |
Kussmann-Gerber S, Wurth C, Scapozza L, Pilger BD, Pliška V, Folkers G. Interaction of the recombinant Herpes Simplex Virus type 1 thymidine kinase with thymidine and aciclovir: A kinetic study Nucleosides and Nucleotides. 18: 311-330. PMID 10358938 DOI: 10.1080/15257779908043078 |
0.211 |
|
| 1998 |
Wild K, Bohner T, Folkers G, Schulz GE. The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Science : a Publication of the Protein Society. 6: 2097-106. PMID 9336833 DOI: 10.1002/Pro.5560061005 |
0.21 |
|
| 1999 |
Gonser S, Crompton NEA, Weber PJA, Beck-Sickinger AG, Folkers G. TP5 triggers signal transduction involving mitogen activated protein kinases in monocytes Journal of Receptor and Signal Transduction Research. 19: 155-166. PMID 10071755 DOI: 10.3109/10799899909036642 |
0.21 |
|
| 2001 |
Wurth C, Thomas RM, Folkers G, Scapozza L. Folding and self-assembly of herpes simplex virus type 1 thymidine kinase. Journal of Molecular Biology. 313: 657-70. PMID 11676546 DOI: 10.1006/Jmbi.2001.5060 |
0.208 |
|
| 2002 |
Flückiger S, Mittl PR, Scapozza L, Fijten H, Folkers G, Grütter MG, Blaser K, Crameri R. Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. Journal of Immunology (Baltimore, Md. : 1950). 168: 1267-72. PMID 11801664 DOI: 10.4049/Jimmunol.168.3.1267 |
0.204 |
|
| 1999 |
Poenaru S, Lamas JR, Folkers G, López de Castro JA, Seebach D, Rognan D. Nonapeptide analogues containing (R)-3-hydroxybutanoate and beta-homoalanine oligomers: synthesis and binding affinity to a class I major histocompatibility complex protein. Journal of Medicinal Chemistry. 42: 2318-31. PMID 10395472 DOI: 10.1021/Jm981123L |
0.2 |
|
| 2011 |
Busso D, Peleg Y, Heidebrecht T, Romier C, Jacobovitch Y, Dantes A, Salim L, Troesch E, Schuetz A, Heinemann U, Folkers GE, Geerlof A, Wilmanns M, Polewacz A, Quedenau C, et al. Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study. Journal of Structural Biology. 175: 159-70. PMID 21382497 DOI: 10.1016/J.Jsb.2011.03.004 |
0.2 |
|
| 2004 |
Otto VI, Schürpf T, Folkers G, Cummings RD. Sialylated complex-type N-glycans enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes. The Journal of Biological Chemistry. 279: 35201-9. PMID 15201278 DOI: 10.1074/Jbc.M404947200 |
0.196 |
|
| 2023 |
Beriashvili D, Yao R, D'Amico F, Krafčíková M, Gurinov A, Safeer A, Cai X, Mulder MPC, Liu Y, Folkers GE, Baldus M. A high-field cellular DNP-supported solid-state NMR approach to study proteins with sub-cellular specificity. Chemical Science. 14: 9892-9899. PMID 37736634 DOI: 10.1039/d3sc02117c |
0.196 |
|
| 1997 |
Joore J, Timmermans A, de van Water S, Folkers GE, van der Saag PT, Zivkovic D. Domains of retinoid signalling and neurectodermal expression of zebrafish otx1 and goosecoid are mutually exclusive Biochemistry and Cell Biology. 75: 601-612. DOI: 10.1139/O97-061 |
0.195 |
|
| 2021 |
Narasimhan S, Pinto C, Lucini Paioni A, van der Zwan J, Folkers GE, Baldus M. Characterizing proteins in a native bacterial environment using solid-state NMR spectroscopy. Nature Protocols. PMID 33442051 DOI: 10.1038/s41596-020-00439-4 |
0.195 |
|
| 1995 |
Kern P, Rognan D, Folkers G. MD simulations in Pseudo-Particle Fluids: Applications to active-site Protein Complexes Quantitative Structure-Activity Relationships. 14: 229-241. DOI: 10.1002/Qsar.19950140302 |
0.194 |
|
| 2019 |
Narasimhan S, Scherpe S, Lucini Paioni A, van der Zwan J, Folkers GE, Ovaa H, Baldus M. Back Cover: DNP‐Supported Solid‐State NMR Spectroscopy of Proteins Inside Mammalian Cells (Angew. Chem. Int. Ed. 37/2019) Angewandte Chemie International Edition. 58: 13162-13162. DOI: 10.1002/Anie.201908849 |
0.192 |
|
| 2018 |
Geng C, Vangone A, Folkers GE, Xue LC, Bonvin AMJJ. iSEE: Interface Structure, Evolution and Energy-based machine learning predictor of binding affinity changes upon mutations. Proteins. PMID 30417935 DOI: 10.1002/prot.25630 |
0.192 |
|
| 1997 |
Rognan D, Krebs S, Kuonen O, Lamas JR, López de Castro JA, Folkers G. Fine specificity of antigen binding to two class I major histocompatibility proteins (B*2705 and B*2703) differing in a single amino acid residue. Journal of Computer-Aided Molecular Design. 11: 463-78. PMID 9385550 DOI: 10.1023/A:1007963901092 |
0.191 |
|
| 2010 |
SEEBACH D, POENARU S, FOLKERS G, ROGNAN D. ChemInform Abstract: Synthesis of Oligo(3-hydroxybutanoate)(OHB)-Containing Peptides with High Binding Affinity to a Class-I-MHC Protein. Cheminform. 29: no-no. DOI: 10.1002/chin.199838238 |
0.189 |
|
| 1995 |
Rognan D, Scapozza L, Folkers G, Daser A. Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen. Proceedings of the National Academy of Sciences of the United States of America. 92: 753-7. PMID 7846047 DOI: 10.1073/Pnas.92.3.753 |
0.187 |
|
| 1994 |
Folkers G. Modelling of ligand-protein interaction complexes as a basis of drug design European Journal of Pharmaceutical Sciences. 2: 31-33. DOI: 10.1016/0928-0987(94)90060-4 |
0.185 |
|
| 2019 |
Narasimhan S, Scherpe S, Lucini Paioni A, van der Zwan J, Folkers GE, Ovaa H, Baldus M. Rücktitelbild: DNP‐Supported Solid‐State NMR Spectroscopy of Proteins Inside Mammalian Cells (Angew. Chem. 37/2019) Angewandte Chemie. 131: 13296-13296. DOI: 10.1002/Ange.201908849 |
0.184 |
|
| 1997 |
Michael M, Gerber S, Fetzer J, Folkers G. Oligonucleotide-directed mutagenesis and subsequent expression of the corresponding recombinant proteins without changing the bacterial vector system. Pharmaceutica Acta Helvetiae. 72: 139-43. PMID 9204772 DOI: 10.1016/S0031-6865(97)00006-X |
0.183 |
|
| 2001 |
Cavalli A, Dezi C, Folkers G, Scapozza L, Recanatini M. Three-dimensional model of the cyclin-dependent kinase 1 (CDK1): Ab initio active site parameters for molecular dynamics studies of CDKs Proteins: Structure, Function and Genetics. 45: 478-485. PMID 11746695 DOI: 10.1002/Prot.10013 |
0.183 |
|
| 1999 |
Gonser S, Stalder J, Folkers G. Vaccines and their transfection potency Vaccine. 17: 2113-2116. PMID 10367943 DOI: 10.1016/S0264-410X(99)00007-9 |
0.182 |
|
| 1999 |
Christians FC, Scapozza L, Crameri A, Folkers G, Stemmer WPC. Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling Nature Biotechnology. 17: 259-264. PMID 10096293 DOI: 10.1038/7003 |
0.181 |
|
| 2013 |
Koch CP, Perna AM, Pillong M, Todoroff NK, Wrede P, Folkers G, Hiss JA, Schneider G. Scrutinizing MHC-I binding peptides and their limits of variation. Plos Computational Biology. 9: e1003088. PMID 23754940 DOI: 10.1371/Journal.Pcbi.1003088 |
0.181 |
|
| 2006 |
Berrow NS, Büssow K, Coutard B, Diprose J, Ekberg M, Folkers GE, Levy N, Lieu V, Owens RJ, Peleg Y, Pinaglia C, Quevillon-Cheruel S, Salim L, Scheich C, Vincentelli R, et al. Recombinant protein expression and solubility screening in Escherichia coli: a comparative study. Acta Crystallographica. Section D, Biological Crystallography. 62: 1218-26. PMID 17001098 DOI: 10.1107/S0907444906031337 |
0.18 |
|
| 1999 |
Pilger BD, Perozzo R, Alber F, Wurth C, Folkers G, Scapozza L. Substrate diversity of herpes simplex virus thymidine kinase. Impact of the kinematics of the enzyme Journal of Biological Chemistry. 274: 31967-31973. PMID 10542226 DOI: 10.1074/Jbc.274.45.31967 |
0.178 |
|
| 2006 |
Birringer MS, Perozzo R, Kut E, Stillhart C, Surber W, Scapozza L, Folkers G. High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics Protein Expression and Purification. 47: 506-515. PMID 16473525 DOI: 10.1016/J.Pep.2006.01.001 |
0.178 |
|
| 2003 |
Pospisil P, Ballmer P, Scapozza L, Folkers G. Tautomerism in computer-aided drug design. Journal of Receptor and Signal Transduction Research. 23: 361-71. PMID 14753297 DOI: 10.1081/Rrs-120026975 |
0.177 |
|
| 1995 |
Folkers GE, van Heerde EC, van der Saag PT. Activation function 1 of retinoic acid receptor beta 2 is an acidic activator resembling VP16. The Journal of Biological Chemistry. 270: 23552-9. PMID 7559520 DOI: 10.1074/jbc.270.40.23552 |
0.176 |
|
| 2000 |
Dédier S, Reinelt S, Reitinger T, Folkers G, Rognan D. Thermodynamic stability of HLA-B*2705-peptide complexes: Effect of peptide and major histocompatibility complex protein mutations Journal of Biological Chemistry. 275: 27055-27061. PMID 10823832 DOI: 10.1074/Jbc.M002777200 |
0.175 |
|
| 1993 |
Fetzer J, Folkers G, Müller I, Keil GM. Site-directed mutagenesis in the active site of the herpes simplex virus type 1 thymidine kinase gene. Virus Genes. 7: 205-9. PMID 8396286 DOI: 10.1007/Bf01702400 |
0.172 |
|
| 1995 |
Czaplicki J, Michael M, Folkers G, Milon A. Preliminary study of substrate binding to thymidine kinase by transferred NOE Journal De Chimie Physique. 92: 1773-1776. DOI: 10.1051/jcp/1995921773 |
0.17 |
|
| 1996 |
Czaplicki J, Bohner T, Habermann AK, Folkers G, Milon A. A transferred NOE study of a tricyclic analog of acyclovir bound to thymidine kinase. Journal of Biomolecular Nmr. 8: 261-72. PMID 8953217 DOI: 10.1007/Bf00410325 |
0.169 |
|
| 2008 |
Michael M, Fetzer J, Folkers G. Site-Directed Mutagenesis Clarifies the Substrate Position within the Three-Dimensional Model of the Active Site of Herpes Simplex Virus Type-1 Thymidine Kinase European Journal of Biochemistry. 226: 219-226. DOI: 10.1111/J.1432-1033.1994.0T219.X |
0.167 |
|
| 2000 |
Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L. Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine Biochemistry. 39: 9597-9603. PMID 10924157 DOI: 10.2210/Pdb1E2K/Pdb |
0.165 |
|
| 2005 |
Yarim M, Moro S, Huber R, Meier PJ, Kaseda C, Kashima T, Hagenbuch B, Folkers G. Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates Bioorganic and Medicinal Chemistry. 13: 463-471. PMID 15598568 DOI: 10.1016/J.Bmc.2004.10.009 |
0.165 |
|
| 1995 |
Fetzer J, Michael M, Bohner T, Hofbauer R, Folkers G. A fast method for obtaining highly pure recombinant herpes simplex virus type 1 thymidine kinase. Protein Expression and Purification. 5: 432-41. PMID 7827501 DOI: 10.1006/Prep.1994.1062 |
0.164 |
|
| 2015 |
Baker LA, Folkers GE, Sinnige T, Houben K, Kaplan M, van der Cruijsen EA, Baldus M. Magic-angle-spinning solid-state NMR of membrane proteins. Methods in Enzymology. 557: 307-28. PMID 25950971 DOI: 10.1016/Bs.Mie.2014.12.023 |
0.162 |
|
| 1995 |
Wild K, Bohner T, Aubry A, Folkers G, Schulz GE. The three-dimensional structure of thymidine kinase from herpes simplex virus type 1. Febs Letters. 368: 289-92. PMID 7628623 DOI: 10.1016/0014-5793(95)00680-8 |
0.157 |
|
| 2006 |
Lack G, Homberger-Zizzari E, Folkers G, Scapozza L, Perozzo R. Recombinant expression and biochemical characterization of the unique elongating β-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates Journal of Biological Chemistry. 281: 9538-9546. PMID 16467310 DOI: 10.1074/Jbc.M509119200 |
0.156 |
|
| 2024 |
Beriashvili D, Zhou J, Liu Y, Folkers GE, Baldus M. Cellular Applications of DNP Solid-State NMR -State of the Art and a Look to the Future. Chemistry (Weinheim An Der Bergstrasse, Germany). e202400323. PMID 38451060 DOI: 10.1002/chem.202400323 |
0.156 |
|
| 2001 |
Reinelt S, Dédier S, Asuni G, Folkers G, Rognan D. Mutation of Cys-67 Alters the Thermodynamic Stability of the Human Leukocyte Antigen HLA-B*2705 Journal of Biological Chemistry. 276: 18472-18477. PMID 11279190 DOI: 10.1074/Jbc.M101282200 |
0.154 |
|
| 1989 |
Folkers G, Krug M, Trumpp S. Computer graphic study on models of the molybdenum cofactor of xanthine oxidase. Journal of Computer-Aided Molecular Design. 1: 87-94. PMID 3505588 DOI: 10.1007/Bf01680559 |
0.154 |
|
| 2002 |
Klein CDP, Folkers G. Understanding the Selectivity of Fumagillin for the Methionine Aminopeptidase Type II Oncology Research. 13: 513-520. PMID 12899241 DOI: 10.3727/000000003108748036 |
0.153 |
|
| 2003 |
Folkers G, Kubinyi H, Hoffmann R, Langer T, Scapozza L, Johner R, Ballmer P, Jahnke W. Focal point: Medicinal chemistry: A. Ligand-receptor interactions: From understanding to design Chimia. 57: 57-59. DOI: 10.2533/000942903777679677 |
0.153 |
|
| 1996 |
Behrends HW, Beck-Sickinger AG, Folkers G. Evaluation of the secondary structure of vaccinia-virus thymidine kinase by circular-dichroism spectroscopy of overlapping synthetic peptides. European Journal of Biochemistry. 241: 126-32. PMID 8898897 DOI: 10.1111/J.1432-1033.1996.0126T.X |
0.152 |
|
| 2003 |
Barnett YA, Eger K, Eriksson S, Folkers G, Hansen PE, Hofbauer R, Komitowsky D, Milon A, Munch-Petersen B. Gene technology-based antimetabolite design: the use of an in vitro protein expression system to facilitate antimetabolite design for virally-induced human diseases and malignant conditions. Biotechnology Advances. 12: 663-8. PMID 14545922 DOI: 10.1016/0734-9750(94)90007-8 |
0.151 |
|
| 2005 |
de Graaf C, Pospisil P, Pos W, Folkers G, Vermeulen NP. Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking. Journal of Medicinal Chemistry. 48: 2308-18. PMID 15801824 DOI: 10.1021/Jm049650U |
0.151 |
|
| 1995 |
Beck-Sickinger AG, Kiess M, Kern P, Folkers G. Secondary structure prediction of adenylate kinase by circular dichroism spectroscopy of synthetic peptides. Pharmaceutica Acta Helvetiae. 70: 33-41. PMID 7770476 DOI: 10.1016/0031-6865(94)00049-2 |
0.15 |
|
| 2000 |
Bissantz C, Folkers G, Rognan D. Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations Journal of Medicinal Chemistry. 43: 4759-4767. PMID 11123984 DOI: 10.1021/Jm001044L |
0.15 |
|
| 2001 |
Dédier S, Reinelt S, Rion S, Folkers G, Rognan D. Use of fluorescence polarization to monitor MHC-peptide interactions in solution. Journal of Immunological Methods. 255: 57-66. PMID 11470286 DOI: 10.1016/S0022-1759(01)00423-9 |
0.147 |
|
| 1997 |
Behrends HW, Folkers G, Beck-Sickinger AG. A new approach to secondary structure evaluation: secondary structure prediction of porcine adenylate kinase and yeast guanylate kinase by CD spectroscopy of overlapping synthetic peptide segments. Biopolymers. 41: 213-31. PMID 9004553 DOI: 10.1002/(Sici)1097-0282(199702)41:2<213::Aid-Bip8>3.0.Co;2-W |
0.143 |
|
| 2003 |
Klein CD, Schiffmann R, Folkers G, Piana S, Röthlisberger U. Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity. The Journal of Biological Chemistry. 278: 47862-7. PMID 14514693 DOI: 10.1074/Jbc.M305325200 |
0.143 |
|
| 1999 |
Weber PJ, Eckhard CP, Gonser S, Otto H, Folkers G, Beck-Sickinger AG. On the role of thymopoietins in cell proliferation. Immunochemical evidence for new members of the human thymopoietin family. Biological Chemistry. 380: 653-60. PMID 10430029 DOI: 10.1515/Bc.1999.081 |
0.141 |
|
| 2015 |
Baker LA, Daniëls M, van der Cruijsen EA, Folkers GE, Baldus M. Efficient cellular solid-state NMR of membrane proteins by targeted protein labeling. Journal of Biomolecular Nmr. 62: 199-208. PMID 25956570 DOI: 10.1007/S10858-015-9936-5 |
0.141 |
|
| 1993 |
Pijnappel WW, Hendriks HF, Folkers GE, van den Brink CE, Dekker EJ, Edelenbosch C, van der Saag PT, Durston AJ. The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification. Nature. 366: 340-4. PMID 8247127 DOI: 10.1038/366340A0 |
0.141 |
|
| 1997 |
Schmetzer S, Greenidge P, Kovar KA, Schulze-Alexandru M, Folkers G. Structure-activity relationships of cannabinoids: a joint CoMFA and pseudoreceptor modelling study. Journal of Computer-Aided Molecular Design. 11: 278-92. PMID 9263855 DOI: 10.1023/A:1007960712989 |
0.139 |
|
| 2002 |
Kratz F, Warnecke A, Scheuermann K, Stockmar C, Schwab J, Lazar P, Drückes P, Esser N, Drevs J, Rognan D, Bissantz C, Hinderling C, Folkers G, Fichtner I, Unger C. Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound. Journal of Medicinal Chemistry. 45: 5523-33. PMID 12459020 DOI: 10.1021/Jm020276C |
0.139 |
|
| 1999 |
Van Eijk MJT, Van Rooijen MA, Modina S, Scesi L, Folkers G, Van Tol HTA, Bevers MM, Fisher SR, Lewin HA, Rakacolli D, Galli C, De Vaureix C, Trounson AO, Mummery CL, Gandolfi F. Molecular cloning, genetic mapping, and developmental expression of bovine POU5F1 Biology of Reproduction. 60: 1093-1103. PMID 10208969 |
0.138 |
|
| 1999 |
Alber F, Folkers G, Carloni P. Dimethyl Phosphate: Stereoelectronic versus Environmental Effects Journal of Physical Chemistry B. 103: 6121-6126. DOI: 10.1021/Jp9901038 |
0.138 |
|
| 1994 |
Colombel J, Eger K, Folkers G. ModAnE: MODelling of ANisotropic effects Pharmaceutica Acta Helvetiae. 69: 69-75. DOI: 10.1016/0031-6865(94)90003-5 |
0.137 |
|
| 2001 |
Reinelt S, Marti M, Dédier S, Reitinger T, Folkers G, López De Castro JA, Rognan D. β-Amino Acid Scan of a Class I Major Histocompatibility Complex-restricted Alloreactive T-cell Epitope Journal of Biological Chemistry. 276: 24525-24530. PMID 11342555 DOI: 10.1074/jbc.M102772200 |
0.136 |
|
| 2006 |
Otto VI, Damoc E, Cueni LN, Schürpf T, Frei R, Ali S, Callewaert N, Moise A, Leary JA, Folkers G, Przybylski M. N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry. Glycobiology. 16: 1033-44. PMID 16877748 DOI: 10.1093/Glycob/Cwl032 |
0.135 |
|
| 1999 |
Muszynski IC, Scapozza L, Kovar KA, Folkers G. Quantitative structure-activity relationships of phenyltropanes as inhibitors of three monoamine transporters: Classical and CoMFA studies Quantitative Structure-Activity Relationships. 18: 342-353. DOI: 10.1002/(Sici)1521-3838(199910)18:4<342::Aid-Qsar342>3.0.Co;2-E |
0.134 |
|
| 2008 |
Folkers G, Merz A. Hydrophobic Fields in Quantitative Structure-Activity Relationships Lipophilicity in Drug Action and Toxicology. 4: 219-232. DOI: 10.1002/9783527614998.ch13 |
0.133 |
|
| 1993 |
Weber E, Lehmann HP, Beck-Sickinger AG, Wawrzynczak EJ, Waibel R, Folkers G, Stahel RA. Antibodies to the protein core of the small cell lung cancer workshop antigen cluster-w4 and to the leucocyte workshop antigen CD24 recognize the same short protein sequence leucine-alanine-proline. Clinical and Experimental Immunology. 93: 279-85. PMID 7688677 DOI: 10.1111/J.1365-2249.1993.Tb07980.X |
0.132 |
|
| 1985 |
Folkers G, Höltje HD. Active site molecular modelling of xanthine oxidase inhibitors with antiinflammatory activity Journal of Molecular Graphics. 3: 146-150. DOI: 10.1016/0263-7855(85)80026-6 |
0.132 |
|
| 2002 |
Otto VI, Gloor SM, Frentzel S, Gilli U, Ammann E, Hein AE, Folkers G, Trentz O, Kossmann T, Morganti-Kossmann MC. The production of macrophage inflammatory protein-2 induced by soluble intercellular adhesion molecule-1 in mouse astrocytes is mediated by src tyrosine kinases and p42/44 mitogen-activated protein kinase. Journal of Neurochemistry. 80: 824-34. PMID 11948246 DOI: 10.1046/J.0022-3042.2001.00748.X |
0.13 |
|
| 2003 |
Spadola L, Novellino E, Folkers G, Scapozza L. Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase. European Journal of Medicinal Chemistry. 38: 413-9. PMID 12750029 DOI: 10.1016/S0223-5234(03)00053-9 |
0.13 |
|
| 1999 |
Alber F, Folkers G, Carloni P. Conformational analysis of dimethyl phosphate in aqueous solution: A density functional theory-based molecular dynamics study Journal of Molecular Structure: Theochem. 489: 237-245. DOI: 10.1016/S0166-1280(99)00057-3 |
0.13 |
|
| 2004 |
Raić-Malić S, Johayem A, Ametamey SM, Batinac S, De Clercq E, Folkers G, Scapozza L. Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues Nucleosides, Nucleotides and Nucleic Acids. 23: 1707-1721. PMID 15598073 DOI: 10.1081/Ncn-200033914 |
0.128 |
|
| 2010 |
Folkers G, Klein CDP. ChemInform Abstract: Computational Methods Facilitate the Assignment of Protein Functions Cheminform. 33: no-no. DOI: 10.1002/CHIN.200213283 |
0.125 |
|
| 2001 |
Folkers G, Klein CDP. Computational methods facilitate the assignment of protein functions Angewandte Chemie - International Edition. 40: 4175-4177. DOI: 10.1002/1521-3773(20011119)40:22<4175::AID-ANIE4175>3.0.CO;2-# |
0.124 |
|
| 2003 |
Džolić Z, Cetina M, Kovaček D, Hergold-Brundić A, Mrvoš-Sermek D, Nagl A, Slade N, Pavelić K, Balzarini J, De Clercq E, Zerbe O, Folkers G, Scapozza L, Mintas M. Molecular structures and ab initio molecular orbital calculations of the optically active derivatives of 1-aminocyclopropane-1-carboxylic acid Journal of Molecular Structure. 655: 229-241. DOI: 10.1016/S0022-2860(03)00255-2 |
0.123 |
|
| 2006 |
Kapková P, Heller E, Kugelmann E, Faber J, Bringmann G, Kessler U, Folkers G, Holzgrabe U. Random chemistry as a new tool for the generation of small-compound libraries. Archiv Der Pharmazie. 339: 489-97. PMID 16929558 DOI: 10.1002/Ardp.200600084 |
0.121 |
|
| 1988 |
Schultz JE, Folkers G. Unusual stereospecificity of the potential antidepressant rolipram on the cyclic AMP generating system from rat brain cortex. Pharmacopsychiatry. 21: 83-6. PMID 2839856 DOI: 10.1055/s-2007-1014653 |
0.12 |
|
| 1999 |
Folkers GE, Van Der Burg B, Van Der Saag PT. Promoter architecture, cofactors, and orphan receptors contribute to cell-specific activation of the retinoic acid receptor β2 promoter Journal of Biological Chemistry. 273: 32200-32212. PMID 9822698 DOI: 10.1074/jbc.273.48.32200 |
0.119 |
|
| 1995 |
Michael M, Fetzer J, Folkers G. Site-directed mutagenesis of herpes simplex virus type 1 thymidine kinase opposes the importance of amino acid positions 251, 321 and 348 for selective recognition of substrate analogs. Biochemical and Biophysical Research Communications. 209: 966-73. PMID 7733991 DOI: 10.1006/Bbrc.1995.1592 |
0.118 |
|
| 1991 |
Zimmermann N, Beck-Sickinger AG, Folkers G, Krickl S, Müller I, Jung G. Conformational and epitope mapping of herpes-simplex-virus type-1 thymidine kinase using synthetic peptide segments. European Journal of Biochemistry. 200: 519-28. PMID 1716203 DOI: 10.1111/J.1432-1033.1991.Tb16213.X |
0.117 |
|
| 2000 |
Amrhein I, Wurth C, Bohner T, Hofbauer R, Folkers G, Scapozza L. Highly purified recombinant varicella zoster virus thymidine kinase is a homodimer Protein Expression and Purification. 18: 338-345. PMID 10733888 DOI: 10.1006/Prep.2000.1201 |
0.115 |
|
| 1999 |
Gademann K, Jaun B, Seebach D, Perozzo R, Scapozza L, Folkers G. Temperature-dependent NMR and CD spectra of β-peptides: On the thermal stability of β-peptide helices - Is the folding process of β-peptides non- cooperative? Helvetica Chimica Acta. 82: 1-11. DOI: 10.1002/(Sici)1522-2675(19990113)82:1<1::Aid-Hlca1>3.0.Co;2-N |
0.115 |
|
| 1994 |
Orjala J, Wright AD, Behrends H, Folkers G, Sticher O, Rüegger H, Rali T. Cytotoxic and antibacterial dihydrochalcones from Piper aduncum. Journal of Natural Products. 57: 18-26. PMID 8158163 DOI: 10.1021/Np50103A003 |
0.11 |
|
| 1989 |
Krug M, Folkers G, Haas B, Hess G, Wiesmüller KH, Freund S, Jung G. Molecular dynamics of the alpha-helical epitope of a novel synthetic lipopeptide foot-and-mouth disease virus vaccine. Biopolymers. 28: 499-512. PMID 2470437 DOI: 10.1002/Bip.360280144 |
0.109 |
|
| 2013 |
Koch CP, Perna AM, Weissmüller S, Bauer S, Pillong M, Baleeiro RB, Reutlinger M, Folkers G, Walden P, Wrede P, Hiss JA, Waibler Z, Schneider G. Exhaustive proteome mining for functional MHC-I ligands. Acs Chemical Biology. 8: 1876-81. PMID 23772559 DOI: 10.1021/Cb400252T |
0.107 |
|
| 1995 |
Folkers G, Michael M. Pharmacodynamics of opioids: recent developments. Pharmaceutica Acta Helvetiae. 69: 61-8. PMID 7809173 DOI: 10.1016/0031-6865(94)90002-7 |
0.106 |
|
| 2003 |
Russ P, Schelling P, Scapozza L, Folkers G, Clercq ED, Marquez VE. Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine. Journal of Medicinal Chemistry. 46: 5045-54. PMID 14584954 DOI: 10.1021/Jm030241S |
0.103 |
|
| 2005 |
Kapková P, Heller E, Unger M, Folkers G, Holzgrabe U. Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor. Journal of Medicinal Chemistry. 48: 7496-9. PMID 16279811 DOI: 10.1021/Jm058041Z |
0.098 |
|
| 1994 |
Rupp A, Kovar KA, Beuerle G, Ruf C, Folkers G. A new pharmophoric model for 5-HT reuptake-inhibitors: differentiation of amphetamine analogues. Pharmaceutica Acta Helvetiae. 68: 235-44. PMID 8208746 DOI: 10.1016/0031-6865(94)90054-X |
0.098 |
|
| 1996 |
Folkers G. Structure-based drug design, Acanthus and other symmetry-related things in Erice, Sicily Pharmaceutica Acta Helvetiae. 71: 173-174. DOI: 10.1016/0031-6865(96)00037-4 |
0.097 |
|
| 2017 |
Cloin BMC, De Zitter E, Salas D, Gielen V, Folkers GE, Mikhaylova M, Bergeler M, Krajnik B, Harvey J, Hoogenraad CC, Van Meervelt L, Dedecker P, Kapitein LC. Efficient switching of mCherry fluorescence using chemical caging. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630286 DOI: 10.1073/Pnas.1617280114 |
0.094 |
|
| 1999 |
Gonser S, Weber E, Folkers G. Peptides and polypeptides as modulators of the immune response: Thymopentin - An example with unknown mode of action Pharmaceutica Acta Helvetiae. 73: 265-273. PMID 10443171 DOI: 10.1016/S0031-6865(99)00005-9 |
0.094 |
|
| 1993 |
Rognan D, Folkers G. Molecular dynamics simulations of viral peptides bound to class I MHC proteins Journal of Molecular Graphics. 11: 259. DOI: 10.1016/0263-7855(93)80011-F |
0.092 |
|
| 2002 |
Sulpizi M, Folkers G, Rothlisberger U, Carloni P, Scapozza L. Applications of density functional theory-based methods in medicinal chemistry Quantitative Structure-Activity Relationships. 21: 173-181. DOI: 10.1002/1521-3838(200207)21:2<173::Aid-Qsar173>3.0.Co;2-B |
0.092 |
|
| 2001 |
Schelling P, Folkers G, Scapozza L. A spectrophotometric assay for quantitative determination of kcat of herpes simplex virus type 1 thymidine kinase substrates Analytical Biochemistry. 295: 82-87. PMID 11476548 DOI: 10.1006/Abio.2001.5191 |
0.091 |
|
| 1993 |
Kern P, Folkers G. Molecular dynamics simulation of an active site-reduced model of the adenylate kinase from escherichia coli Journal of Molecular Graphics. 11: 277. DOI: 10.1016/0263-7855(93)80050-2 |
0.091 |
|
| 1993 |
Kruyt FA, Folkers GE, Walhout AJ, van der Leede BJ, van der Saag PT. E1A functions as a coactivator of retinoic acid-dependent retinoic acid receptor-beta 2 promoter activation. Molecular Endocrinology (Baltimore, Md.). 7: 604-15. PMID 8389000 DOI: 10.1210/mend.7.4.8389000 |
0.088 |
|
| 1992 |
Krug M, Folkers G. ADAPTU: animated dynamics analysis program at Tübingen University. Journal of Molecular Graphics. 9: 119-21, 102. PMID 1722700 DOI: 10.1016/0263-7855(91)85009-N |
0.088 |
|
| 1988 |
Visser B, van der Salm T, van den Brink W, Folkers G. Genes from Bacillus thuringiensis entomocidus 60.5 coding for insect-specific crystal proteins Molecular and General Genetics Mgg. 212: 219-224. DOI: 10.1007/BF00334688 |
0.088 |
|
| 2004 |
Gonser S, Crompton NE, Folkers G, Weber E. Increased radiation toxicity by enhanced apoptotic clearance of HL-60 cells in the presence of the pentapeptide thymopentin, which selectively binds to apoptotic cells. Mutation Research. 558: 19-26. PMID 15036115 DOI: 10.1016/J.Mrgentox.2003.10.010 |
0.086 |
|
| 2014 |
Hiss JA, Reutlinger M, Koch CP, Perna AM, Schneider P, Rodrigues T, Haller S, Folkers G, Weber L, Baleeiro RB, Walden P, Wrede P, Schneider G. Combinatorial chemistry by ant colony optimization. Future Medicinal Chemistry. 6: 267-80. PMID 24575965 DOI: 10.4155/Fmc.13.203 |
0.086 |
|
| 2003 |
Pizzagalli F, Varga Z, Huber RD, Folkers G, Meier PJ, St-Pierre MV. Identification of steroid sulfate transport processes in the human mammary gland. The Journal of Clinical Endocrinology and Metabolism. 88: 3902-12. PMID 12915686 DOI: 10.1210/Jc.2003-030174 |
0.086 |
|
| 2004 |
Altznauer F, Conus S, Cavalli A, Folkers G, Simon HU. Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. The Journal of Biological Chemistry. 279: 5947-57. PMID 14612448 DOI: 10.1074/Jbc.M308576200 |
0.085 |
|
| 2002 |
Pizzagalli F, Hagenbuch B, Stieger B, Klenk U, Folkers G, Meier PJ. Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter Molecular Endocrinology. 16: 2283-2296. PMID 12351693 DOI: 10.1210/Me.2001-0309 |
0.083 |
|
| 2007 |
Huber RD, Gao B, Pfändler MAS, Zhang-Fu W, Leuthold S, Hagenbuch B, Folkers G, Meier PJ, Stieger B. Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain American Journal of Physiology - Cell Physiology. 292: C795-C806. PMID 16971491 DOI: 10.1152/Ajpcell.00597.2005 |
0.073 |
|
| 1998 |
Pijnappel WW, Folkers GE, de Jonge WJ, Verdegem PJ, de Laat SW, Lugtenburg J, Hendriks HF, van der Saag PT, Durston AJ. Metabolism to a response pathway selective retinoid ligand during axial pattern formation. Proceedings of the National Academy of Sciences of the United States of America. 95: 15424-9. PMID 9860984 DOI: 10.1073/Pnas.95.26.15424 |
0.07 |
|
| 1992 |
Zimmermann N, Rötzschke O, Falk K, Rognan D, Folkers G, Rammensee H, Jung G. Molecular Modeling of the Class I Human Histocompatibility Molecule HLA-A2 Presenting an Allele-Specific Nonapeptide from Influenza Matrix Protein Angewandte Chemie International Edition in English. 31: 886-890. DOI: 10.1002/Anie.199208861 |
0.068 |
|
| 2000 |
Dédier S, Reinelt S, Reitinger T, Folkers G, Rognan D. Thermodynamic Stability of HLA-B*2705·Peptide Complexes Journal of Biological Chemistry. 275: 27055-27061. DOI: 10.1016/s0021-9258(19)61479-1 |
0.066 |
|
| 1997 |
Camenisch G, Folkers G, van de Waterbeemd H. Review of theoretical passive drug absorption models: historical background, recent developments and limitations. Pharmaceutica Acta Helvetiae. 71: 309-27. PMID 8973162 DOI: 10.1016/S0031-6865(96)00031-3 |
0.063 |
|
| 2005 |
Bertschi I, Collomb M, Rist L, Eberhard P, Sieber R, Bütikofer U, Wechsler D, Folkers G, von Mandach U. Maternal dietary Alpine butter intake affects human milk: fatty acids and conjugated linoleic acid isomers. Lipids. 40: 581-7. PMID 16149737 DOI: 10.1007/S11745-005-1419-8 |
0.063 |
|
| 2001 |
Zhou X, Gonnet G, Hallett M, Münchbach M, Folkers G, James P. Cell fingerprinting: An approach to classifying cells according to mass profiles of digests of protein extracts Proteomics. 1: 683-690. PMID 11678037 DOI: 10.1002/1615-9861(200104)1:5<683::Aid-Prot683>3.0.Co;2-3 |
0.061 |
|
| 1996 |
Gerber S, Folkers G. A new method for quantitative determination of tritium-labeled nucleoside kinase products adsorbed on DEAE-cellulose Biochemical and Biophysical Research Communications. 225: 263-267. PMID 8769128 DOI: 10.1006/Bbrc.1996.1164 |
0.061 |
|
| 2010 |
WEBER PJA, BADER JE, FOLKERS G, BECK-SICKINGER AG. ChemInform Abstract: A Fast and Inexpensive Method for N-Terminal Fluorescein-Labeling of Peptides. Cheminform. 29: no-no. DOI: 10.1002/chin.199826243 |
0.058 |
|
| 2005 |
Hofstetter B, Vuong V, Broggini-Tenzer A, Bodis S, Ciernik IF, Fabbro D, Wartmann M, Folkers G, Pruschy M. Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo Clinical Cancer Research. 11: 1588-1596. PMID 15746064 DOI: 10.1158/1078-0432.Ccr-04-1800 |
0.058 |
|
| 2005 |
Raic-Malic S, Johayem A, Ametamey SM, Batinac S, De Clercq E, Folkers G, Scapozza L. Synthesis,18F-Radiolabelling and Biological Evaluations of C-6 Alkylated Pyrimidine Nucleoside Analogues. Cheminform. 36. DOI: 10.1002/CHIN.200517203 |
0.057 |
|
| 2005 |
HOLZER B, STIEGER B, FOLKERS G, MEIER P, FATTINGER K. Differential regulation of basolateral and canalicular transporter expression in rat liver in chronic renal failure Clinical Pharmacology & Therapeutics. 77: P34-P34. DOI: 10.1016/J.Clpt.2004.12.023 |
0.056 |
|
| 2007 |
Iqbal J, Scapozza L, Folkers G, Müller CE. Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 846: 281-290. PMID 17023224 DOI: 10.1016/J.Jchromb.2006.09.018 |
0.055 |
|
| 1995 |
van der Leede BJ, Folkers GE, van den Brink CE, van der Saag PT, van der Burg B. Retinoic acid receptor alpha 1 isoform is induced by estradiol and confers retinoic acid sensitivity in human breast cancer cells. Molecular and Cellular Endocrinology. 109: 77-86. PMID 7789618 DOI: 10.1016/0303-7207(95)03487-R |
0.055 |
|
| 1998 |
Camenisch G, Alsenz J, van de Waterbeemd H, Folkers G. Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 6: 317-324. PMID 9795088 DOI: 10.1016/S0928-0987(97)10019-7 |
0.054 |
|
| 1998 |
Holtje HD, Folkers G, Luzar A. Molecular Modeling, Basic Principles and Applications Computers in Physics. 12: 41. DOI: 10.1063/1.168645 |
0.053 |
|
| 1996 |
van De Waterbeemd H, Camenisch G, Folkers G, Raevsky OA. Estimation of Caco-2 Cell Permeability using Calculated Molecular Descriptors Quantitative Structure-Activity Relationships. 15: 480-490. DOI: 10.1002/Qsar.19960150604 |
0.051 |
|
| 2003 |
Prekupec S, Svedruzić D, Gazivoda T, Mrvos-Sermek D, Nagl A, Grdisa M, Pavelić K, Balzarini J, De Clercq E, Folkers G, Scapozza L, Mintas M, Raić-Malić S. Synthesis and biological evaluation of iodinated and fluorinated 9-(2-hydroxypropyl) and 9-(2-hydroxyethoxy)methyl purine nucleoside analogues. Journal of Medicinal Chemistry. 46: 5763-72. PMID 14667229 DOI: 10.1021/Jm0308747 |
0.051 |
|
| 2003 |
Khov-Tran VV, Hanser CFW, Folkers G. Vireal Lab - From instruction to construction Chimia. 57: 121-127. DOI: 10.2533/000942903777679659 |
0.05 |
|
| 1999 |
Weber PJ, Bader JE, Folkers G, Beck-Sickinger AG. A fast and inexpensive method for N-terminal fluorescein-labeling of peptides. Bioorganic & Medicinal Chemistry Letters. 8: 597-600. PMID 9871567 DOI: 10.1016/S0960-894X(98)00084-5 |
0.05 |
|
| 1991 |
Houwen FP, Rebers M, Folkers GE, Stams AJM, Zehnder AJB. The use of a two-liquid-phase electron removal system for culture of proton-reducing bacteria Journal of Microbiological Methods. 13: 223-230. DOI: 10.1016/0167-7012(91)90048-U |
0.049 |
|
| 1988 |
EGER K, FOLKERS G, FREY M, ZIMMERMANN W, KOOP-KIRFEL G. ChemInform Abstract: Unusual Addition and Cycloaddition Reactions of 2-Amino-3-cyanopyrroles with Acetylenecarboxylates. Cheminform. 19. DOI: 10.1002/chin.198850188 |
0.049 |
|
| 1997 |
Camenisch G, Folkers G, van de Waterbeemd H. Comparison of passive drug transport through Caco-2 cells and artificial membranes International Journal of Pharmaceutics. 147: 61-70. DOI: 10.1016/S0378-5173(96)04796-5 |
0.048 |
|
| 1998 |
Van De Waterbeemd H, Camenisch G, Folkers G, Chretien JR, Raevsky OA. Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors Journal of Drug Targeting. 6: 151-165. PMID 9886238 DOI: 10.3109/10611869808997889 |
0.045 |
|
| 1995 |
Folkers G. Lock and key Pharmaceutica Acta Helvetiae. 69: 175-176. DOI: 10.1016/0031-6865(95)00004-S |
0.044 |
|
| 1998 |
Camenisch G, Folkers G, Van De Waterbeemd H. Shapes of membrane permeability-lipophilicity curves: Extension of theoretical models with an aqueous pore pathway European Journal of Pharmaceutical Sciences. 6: 321-329. PMID 9795090 DOI: 10.1016/S0928-0987(98)00033-5 |
0.042 |
|
| 2015 |
Martić-Kehl MI, Wernery J, Folkers G, Schubiger PA. Quality of Animal Experiments in Anti-Angiogenic Cancer Drug Development - A Systematic Review. Plos One. 10: e0137235. PMID 26421849 DOI: 10.1371/Journal.Pone.0137235 |
0.039 |
|
| 1995 |
Fenner H, Taylor D, Schattenkirchner M, Folkers G, Zueger S. Immunogenetic profiles correlate with pro-MMP expression in rheumatoid arthritis Acta Orthopaedica Scandinavica. 66: 154-155. DOI: 10.3109/17453679509157678 |
0.038 |
|
| 1994 |
Folkers G. Antibiotics and antiviral compounds, chemical synthesis and modification Pharmaceutica Acta Helvetiae. 68: 195. DOI: 10.1016/0031-6865(94)90045-0 |
0.036 |
|
| 1986 |
FOLKERS G, ROTH HJ. ChemInform Abstract: A Synthetic Route to S-Nitrobenzimidazoles with Heterocyclic Substituents at N-1. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198611213 |
0.034 |
|
| 1992 |
Kugler T, Thibaut U, Abraham M, Folkers G, Göpel W. Chemically modified semiconductor surfaces: 1,4-phenylenediamine on Si(100) Surface Science. 260: 64-74. DOI: 10.1016/0039-6028(92)90019-3 |
0.033 |
|
| 2006 |
Folkers G, Ishai A, Rudin M, Schubiger PA, Bräutigam M, Möhler H, Märki HP. Imaging in biomedical research: Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 18, 2006 Chimia. 60: 805-814. DOI: 10.2533/Chimia.2006.805 |
0.031 |
|
| 1994 |
Merz A, Folkers G. Contribution of electrostatic energies to the comfa analysis of herpes simplex virus thimidine kinase inhibitors Journal of Molecular Graphics. 12: 75-76. DOI: 10.1016/0263-7855(94)80063-4 |
0.031 |
|
| 2016 |
Grüntzig K, Graf R, Boo G, Guscetti F, Hässig M, Axhausen KW, Fabrikant S, Welle M, Meier D, Folkers G, Pospischil A. Swiss Canine Cancer Registry 1955-2008: Occurrence of the Most Common Tumour Diagnoses and Influence of Age, Breed, Body Size, Sex and Neutering Status on Tumour Development. Journal of Comparative Pathology. PMID 27406312 DOI: 10.1016/J.Jcpa.2016.05.011 |
0.03 |
|
| 2015 |
Pospischil A, Folkers G. How much reproducibility do we need in human and veterinary pathology? Experimental and Toxicologic Pathology. 67: 77-80. DOI: 10.1016/j.etp.2014.11.005 |
0.029 |
|
| 2015 |
Graf R, Grüntzig K, Hässig M, Axhausen KW, Fabrikant S, Welle M, Meier D, Guscetti F, Folkers G, Otto V, Pospischil A. Swiss Feline Cancer Registry: A Retrospective Study of the Occurrence of Tumours in Cats in Switzerland from 1965 to 2008. Journal of Comparative Pathology. PMID 26422414 DOI: 10.1016/J.Jcpa.2015.08.007 |
0.028 |
|
| 2015 |
Grüntzig K, Graf R, Hässig M, Welle M, Meier D, Lott G, Erni D, Schenker NS, Guscetti F, Boo G, Axhausen K, Fabrikant S, Folkers G, Pospischil A. The Swiss Canine Cancer Registry: a retrospective study on the occurrence of tumours in dogs in Switzerland from 1955 to 2008. Journal of Comparative Pathology. 152: 161-71. PMID 25824119 DOI: 10.1016/j.jcpa.2015.02.005 |
0.028 |
|
| 1987 |
Eger K, Pfahl JG, Folkers G, Roth HJ. Selected reactions on the o-aminonitrile system of substituted pyrroles Journal of Heterocyclic Chemistry. 24: 425-430. DOI: 10.1002/Jhet.5570240224 |
0.027 |
|
| 2010 |
FOLKERS G. ChemInform Abstract: Molecular Modeling and Computer Aided Drug Design 1992-1993 Cheminform. 25: no-no. DOI: 10.1002/chin.199452209 |
0.027 |
|
| 1987 |
PICHLER H, FOLKERS G, ROTH HJ, EGER K. ChemInform Abstract: Synthesis of 7-Unsubstituted 7H-Pyrrolo(2,3-d)pyrimidines. Cheminform. 18. DOI: 10.1002/chin.198702224 |
0.027 |
|
| 2015 |
Grüntzig K, Graf R, Hässig M, Welle M, Meier D, Lott G, Erni D, Schenker NS, Guscetti F, Boo G, Axhausen K, Fabrikant S, Folkers G, Pospischil A. Corrigendum to "The Swiss Canine Cancer Registry: A Retrospective Study on the Occurrence of Tumours in Dogs in Switzerland from 1955 to 2008" [J Comp Pathol 152 (2-3) (2015) 161-171] Journal of Comparative Pathology. 153. DOI: 10.1016/J.Jcpa.2015.04.008 |
0.027 |
|
| 1986 |
FOLKERS G, ROTH HJ. ChemInform Abstract: A Synthetic Route to Potential Inhibitors of 5-Lipoxygenase. Part 1. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198645184 |
0.026 |
|
| 1987 |
EGER K, FOLKERS G, ZIMMERMANN W, SCHMIDT R, HILLER W. ChemInform Abstract: Unexpected Formation of a Heterocyclic Spiran in the Michael Reaction of Ascorbic Acid with Acrolein. Cheminform. 18. DOI: 10.1002/chin.198752175 |
0.025 |
|
| 2018 |
Sieroka N, Otto VI, Folkers G. Critical Thinking in Education and Research-Why and How? Angewandte Chemie (International Ed. in English). PMID 30320446 DOI: 10.1002/Anie.201810397 |
0.023 |
|
| 2007 |
van de Waterbeemd H, Testa B, Folkers G. Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry Computer-Assisted Lead Finding and Optimization: Current Tools For Medicinal Chemistry. 1-553. DOI: 10.1002/9783906390406 |
0.022 |
|
| 2003 |
Folkers G, Otto M. pnn ag: Pharma Nation Network AG – CME online Chimia International Journal For Chemistry. 57: 345-348. DOI: 10.2533/000942903777679226 |
0.02 |
|
| 1987 |
EGER K, PFAHL JG, FOLKERS G, ROTH HJ. ChemInform Abstract: Selected Reactions on the o-Aminonitrile System of Substituted Pyrroles. Cheminform. 18. DOI: 10.1002/chin.198746236 |
0.02 |
|
| 1990 |
Folkers G. Multivariate Chemometrics in QSAR: A Dialogue. Von P. P. Mager, John Wiley & Sons Inc. New York – Chichester – Toronto – Brisbane – Singapore 1988. 345 S., $ 49.50 Pharmazie in Unserer Zeit. 19: 223-223. DOI: 10.1002/Pauz.19900190514 |
0.02 |
|
| 2014 |
Atmanspacher H, Bezzola Lambert L, Folkers G, Schubiger PA. Relevance relations for the concept of reproducibility Journal of the Royal Society Interface. 11. DOI: 10.1098/rsif.2013.1030 |
0.017 |
|
| 1985 |
Folkers G. Multidimensional Pharmacochemistry, Design of safer drugs; Vol. 20, Series Medicinal Chemistry. Von P. P. Mager; Academic Press New York 1984, 418 S., 17 Abb., 188 Tab., geb. US$ 89, -(ca. DM 400,-). Pharmazie in Unserer Zeit. 14: 158-158. DOI: 10.1002/pauz.19850140524 |
0.017 |
|
| 2003 |
Tran VV, Lichtsteiner S, Ernst B, Otto M, Folkers G. Towards a virtual education in pharmaceutical sciences. An innovative E-learning approach. Current Problems in Dermatology. 32: 43-51. PMID 12471989 DOI: 10.1159/000067345 |
0.015 |
|
| 1993 |
Folkers G. Why a new Pharmaceutica Acta Helvetiae? Pharmaceutica Acta Helvetiae. 68: 1. DOI: 10.1016/0031-6865(93)90002-N |
0.015 |
|
| 2005 |
Meier Y, Cavallaro M, Roos M, Pauli-Magnus C, Folkers G, Meier PJ, Fattinger K. Incidence of drug-i'nduced liver injury in medical inpatients European Journal of Clinical Pharmacology. 61: 135-143. PMID 15726344 DOI: 10.1007/S00228-004-0888-Z |
0.014 |
|
| 1994 |
Folkers G. β-casomorphins and related peptides: Recent developments Pharmaceutica Acta Helvetiae. 69: 54. DOI: 10.1016/0031-6865(94)90034-5 |
0.014 |
|
| 1995 |
Folkers G. Fatalism or efficiency? Pharmaceutica Acta Helvetiae. 70: 1. DOI: 10.1016/0031-6865(95)90631-7 |
0.012 |
|
| 1986 |
Folkers G. QSAR and strategies in the design of bioactive compounds. Von J. K. Seydel; VCH Verlagsgesellschaft, Weinheim/Deerfield Beach, Florida/Basel 1985. XIV/442 S., 150 Abb., 68 Tab., DM 148,– Pharmazie in Unserer Zeit. 15: 29-29. DOI: 10.1002/pauz.19860150119 |
0.011 |
|
| 2016 |
Grüntzig K, Graf R, Boo G, Guscetti F, Hässig M, Axhausen KW, Fabrikant S, Welle M, Meier D, Folkers G, Pospischil A. Swiss Canine Cancer Registry 1955–2008 Journal of Comparative Pathology. 155: 156-170. DOI: 10.3929/Ethz-B-000118646 |
0.011 |
|
| 1994 |
Folkers G. Synthesis in medicinal chemistry, a future orphan discipline? Pharmaceutica Acta Helvetiae. 68: 143. DOI: 10.1016/0031-6865(94)90036-1 |
0.011 |
|
| 1994 |
Thibaut U, Folkers G, Klebe G, Kubinyi H, Merz A, Rognan D. Recommendations for CoMFA Studies and 3D QSAR Publications Qsar & Combinatorial Science. 13: 1-3. DOI: 10.1002/Qsar.19940130102 |
0.01 |
|
| 2020 |
Folkers G. [On the Economization of Medicine]. Praxis. 109: 181-182. PMID 32126907 DOI: 10.1024/1661-8157/A003405 |
0.01 |
|
| 2015 |
Graf R, Grüntzig K, Boo G, Hässig M, Axhausen KW, Fabrikant S, Welle M, Meier D, Guscetti F, Folkers G, Otto V, Pospischil A. Swiss Feline Cancer Registry 1965-2008: The Influence of Sex, Breed and Age on Tumour Types and Tumour Locations Journal of Comparative Pathology. DOI: 10.1016/j.jcpa.2016.01.008 |
0.01 |
|
| 2010 |
FOLKERS G, MICHAEL M. ChemInform Abstract: Pharmacodynamics of Opioids: Recent Developments Cheminform. 26: no-no. DOI: 10.1002/chin.199515331 |
0.01 |
|
| 2007 |
Testa B, Krämer SD, Wunderli-Allenspach H, Folkers G. Pharmacokinetic Profiling in Drug Research Pharmacokinetic Profiling in Drug Research. 1-493. DOI: 10.1002/9783906390468 |
0.01 |
|
| 2004 |
Hofstetter B, Vuong V, Broggini-Tenzer A, Wartmann M, Fabbro D, Bodis S, Folkers G, Pruschy M. 537 Multidrug-resistant tumors treated with Epothilone B in combination with clinically relevant doses of ionizing radiation European Journal of Cancer Supplements. 2: 163-164. DOI: 10.1016/S1359-6349(04)80545-7 |
0.01 |
|
| 2002 |
Chen HY, Liu F, Hou CMH, Huang JSW, Sharma BB, Chang TW, Schmidt M, Hoffman DR, Yagami T, Folkers G, Crameri R, Hileman RE, Silvanovich A, Goodman RE, Rice EA, et al. Contents Vol. 128, 2002 International Archives of Allergy and Immunology. 128: 357-358. DOI: 10.1159/000065988 |
0.01 |
|
| 2002 |
Chen HY, Liu F, Hou CMH, Huang JSW, Sharma BB, Chang TW, Schmidt M, Hoffman DR, Yagami T, Folkers G, Crameri R, Hileman RE, Silvanovich A, Goodman RE, Rice EA, et al. Subject Index Vol. 128, 2002 International Archives of Allergy and Immunology. 128: 355-356. DOI: 10.1159/000065987 |
0.01 |
|
| 1995 |
Folkers G. Snails and shells teach us Pharmaceutica Acta Helvetiae. 70: 267-268. DOI: 10.1016/0031-6865(96)89544-6 |
0.01 |
|
| 1995 |
Folkers G. Is pharmacy an interdisciplinary science? Pharmaceutica Acta Helvetiae. 70: 201. DOI: 10.1016/0031-6865(95)90115-E |
0.01 |
|
| 1995 |
Folkers G. Biochemistry of redox reaction Pharmaceutica Acta Helvetiae. 70: 263. DOI: 10.1016/0031-6865(95)90003-9 |
0.01 |
|
| 1994 |
Folkers G. Genetic engineering and biotechnology, the future of making drugs? Pharmaceutica Acta Helvetiae. 69: 1. PMID 7938071 DOI: 10.1016/0031-6865(94)90023-X |
0.01 |
|
| 1994 |
Folkers G. The Pharmaceutical codex, principles and practice of pharmaceutics Pharmaceutica Acta Helvetiae. 69: 53. DOI: 10.1016/0031-6865(94)90033-7 |
0.01 |
|
| 1994 |
Folkers G. Tadeus Reichstein medal awarded to William I. Higuchi Pharmaceutica Acta Helvetiae. 69: 117-118. DOI: 10.1016/0031-6865(94)90011-6 |
0.01 |
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