| Year |
Citation |
Score |
| 2024 |
Rybnicek J, Chen Y, Milic M, Tio ES, McLaurin J, Hohman TJ, De Jager PL, Schneider JA, Wang Y, Bennett DA, Tripathy S, Felsky D, Lambe EK. CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer's disease. Translational Psychiatry. 14: 83. PMID 38331937 DOI: 10.1038/s41398-024-02785-3 |
0.321 |
|
| 2022 |
Morrone CD, Lai AY, Bishay J, Hill ME, McLaurin J. Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer's disease. Translational Neurodegeneration. 11: 26. PMID 35501886 DOI: 10.1186/s40035-022-00300-6 |
0.334 |
|
| 2021 |
Lai AY, Joo IL, Trivedi AU, Dorr A, Hill ME, Stefanovic B, McLaurin J. Cerebrovascular damage after midlife transient hypertension in non-transgenic and Alzheimer's disease rats. Brain Research. 147369. PMID 33582120 DOI: 10.1016/j.brainres.2021.147369 |
0.309 |
|
| 2021 |
Liu M, Beckett T, Am Thomason L, Dorr A, Stefanovic B, McLaurin J. Covert strokes prior to Alzheimer's disease onset accelerate peri-lesional pathology but not cognitive deficits in an inducible APP mouse model. Brain Research. 147233. PMID 33412147 DOI: 10.1016/j.brainres.2020.147233 |
0.302 |
|
| 2020 |
Morrone CD, Bishay J, McLaurin J. Potential Role of Venular Amyloid in Alzheimer's Disease Pathogenesis. International Journal of Molecular Sciences. 21. PMID 32183293 DOI: 10.3390/ijms21061985 |
0.358 |
|
| 2019 |
Morrone CD, Bazzigaluppi P, Beckett TL, Hill ME, Koletar MM, Stefanovic B, McLaurin J. Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-β attenuation. Brain : a Journal of Neurology. PMID 31782760 DOI: 10.1093/brain/awz371 |
0.367 |
|
| 2019 |
Proulx É, Power SK, Oliver DK, Sargin D, McLaurin J, Lambe EK. Apamin Improves Prefrontal Nicotinic Impairment in Mouse Model of Alzheimer's Disease. Cerebral Cortex (New York, N.Y. : 1991). PMID 31188425 DOI: 10.1093/cercor/bhz107 |
0.507 |
|
| 2017 |
Liu M, Jevtic S, Markham-Coultes K, Ellens NPK, O'Reilly MA, Hynynen K, Aubert I, McLaurin J. Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease. Brain Research. PMID 29066368 DOI: 10.1016/J.Brainres.2017.10.015 |
0.302 |
|
| 2017 |
Bazzigaluppi P, Beckett TL, Koletar MM, Lai AY, Joo IL, Brown ME, Carlen PL, McLaurin J, Stefanovic B. Early stage attenuation of phase amplitude coupling in the hippocampus and medial prefrontal cortex in a transgenic rat model of AD. Journal of Neurochemistry. PMID 28777881 DOI: 10.1111/Jnc.14136 |
0.333 |
|
| 2017 |
Lai AY, McLaurin J. Rho-associated protein kinases as therapeutic targets for both vascular and parenchymal pathologies in Alzheimer's disease. Journal of Neurochemistry. PMID 28722749 DOI: 10.1111/jnc.14130 |
0.337 |
|
| 2017 |
Joo IL, Lai AY, Bazzigaluppi P, Koletar MM, Dorr A, Brown ME, Thomason LA, Sled JG, McLaurin J, Stefanovic B. Early neurovascular dysfunction in a transgenic rat model of Alzheimer's disease. Scientific Reports. 7: 46427. PMID 28401931 DOI: 10.1038/Srep46427 |
0.328 |
|
| 2016 |
Morrone CD, Thomason LA, Brown ME, Aubert I, McLaurin J. Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease. Plos One. 11: e0165393. PMID 27768761 DOI: 10.1371/journal.pone.0165393 |
0.372 |
|
| 2016 |
Ma K, McLaurin J. α-Melanocyte Stimulating Hormone as a Potential Therapy for Alzheimer's Disease. Current Alzheimer Research. PMID 27539595 |
0.378 |
|
| 2015 |
Proulx É, Fraser P, McLaurin J, Lambe EK. Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12779-91. PMID 26377466 DOI: 10.1523/Jneurosci.4501-14.2015 |
0.501 |
|
| 2015 |
Morrone CD, Liu M, Black SE, McLaurin J. Interaction between therapeutic interventions for Alzheimer's disease and physiological Aβ clearance mechanisms. Frontiers in Aging Neuroscience. 7: 64. PMID 25999850 DOI: 10.3389/Fnagi.2015.00064 |
0.332 |
|
| 2015 |
Lai AY, Dorr A, Thomason LA, Koletar MM, Sled JG, Stefanovic B, McLaurin J. Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer's disease. Brain : a Journal of Neurology. 138: 1046-58. PMID 25688079 DOI: 10.1093/Brain/Awv023 |
0.325 |
|
| 2014 |
Ma K, McLaurin J. α-Melanocyte stimulating hormone prevents GABAergic neuronal loss and improves cognitive function in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6736-45. PMID 24828629 DOI: 10.1523/JNEUROSCI.5075-13.2014 |
0.339 |
|
| 2014 |
Hawkes CA, Shaw JE, Brown M, Sampson AP, McLaurin J, Carare RO. MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice. Neuro-Degenerative Diseases. 13: 17-23. PMID 24021653 DOI: 10.1159/000351096 |
0.328 |
|
| 2013 |
Thomason LAM, Stefanovic B, Mclaurin J. Cerebrovascular contributions to Alzheimer's disease pathophysiology and potential therapeutic interventions in mouse models European Journal of Neuroscience. 37: 1994-2004. PMID 23773069 DOI: 10.1111/ejn.12181 |
0.342 |
|
| 2012 |
Dorr A, Sahota B, Chinta LV, Brown ME, Lai AY, Ma K, Hawkes CA, McLaurin J, Stefanovic B. Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease. Brain : a Journal of Neurology. 135: 3039-50. PMID 23065792 DOI: 10.1093/brain/aws243 |
0.356 |
|
| 2012 |
Ma K, Thomason LA, McLaurin J. scyllo-Inositol, preclinical, and clinical data for Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 177-212. PMID 22840748 DOI: 10.1016/B978-0-12-394816-8.00006-4 |
0.356 |
|
| 2012 |
Lai AY, McLaurin J. Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1822: 1629-1637. PMID 22800931 DOI: 10.1016/j.bbadis.2012.07.003 |
0.327 |
|
| 2012 |
Girão da Cruz MT, Jordão J, Dasilva KA, Ayala-Grosso CA, Ypsilanti A, Weng YQ, Laferla FM, McLaurin J, Aubert I. Early increases in soluble amyloid-β levels coincide with cholinergic degeneration in 3xTg-AD mice. Journal of Alzheimer's Disease : Jad. 32: 267-72. PMID 22776965 DOI: 10.3233/Jad-2012-100732 |
0.351 |
|
| 2012 |
Hawkes CA, Deng L, Fenili D, Nitz M, McLaurin J. In vivo uptake of β-amyloid by non-plaque associated microglia. Current Alzheimer Research. 9: 890-901. PMID 22272621 DOI: 10.2174/156720512803251084 |
0.336 |
|
| 2012 |
Lai A, McLaurin J. P2-086: Inhibition of beta-amyloid peptide aggregation by scyllo-inositol rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer's disease Alzheimer's & Dementia. 8: P293-P293. DOI: 10.1016/j.jalz.2012.05.790 |
0.337 |
|
| 2011 |
Ma K, Mount HT, McLaurin J. Region-specific distribution of β-amyloid peptide and cytokine expression in TgCRND8 mice. Neuroscience Letters. 492: 5-10. PMID 21295112 DOI: 10.1016/j.neulet.2011.01.035 |
0.335 |
|
| 2010 |
Lai AY, McLaurin J. Mechanisms of amyloid-Beta Peptide uptake by neurons: the role of lipid rafts and lipid raft-associated proteins. International Journal of Alzheimer's Disease. 2011: 548380. PMID 21197446 DOI: 10.4061/2011/548380 |
0.304 |
|
| 2009 |
Hawkes CA, McLaurin J. Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy. Proceedings of the National Academy of Sciences of the United States of America. 106: 1261-6. PMID 19164591 DOI: 10.1073/pnas.0805453106 |
0.303 |
|
| 2009 |
Jordao JF, Ayala-Grosso CA, Chopra R, McLaurin J, Aubert I, Hynynena K. Ultrasound delivery of an anti-Aβ therapeutic agent to the brain in a mouse model of Alzheimer's disease Aip Conference Proceedings. 1113: 428-432. DOI: 10.1063/1.3131464 |
0.311 |
|
| 2009 |
DaSilva KA, Brown ME, Cousins JE, Rappaport RV, Aubert I, Westaway D, McLaurin J. scyllo-inositol (ELND005) ameliorates amyloid pathology in an aggressive mouse model of Alzheimer's disease Alzheimers & Dementia. 5: 425. DOI: 10.1016/J.Jalz.2009.04.950 |
0.371 |
|
| 2009 |
Ng V, Gelinas D, Brown M, McLaurin J. P4-194: Modulation of endogenous TGF-β1 reduces microglial proliferation and Aβ deposition in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 5: P488-P488. DOI: 10.1016/j.jalz.2009.04.761 |
0.302 |
|
| 2009 |
Hawkes CA, Ng V, McLaurin J. Small molecule inhibitors of Aβ-aggregation and neurotoxicity Drug Development Research. 70: 111-124. DOI: 10.1002/ddr.20290 |
0.327 |
|
| 2007 |
Fenili D, Brown M, Rappaport R, McLaurin J. Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology. Journal of Molecular Medicine (Berlin, Germany). 85: 603-11. PMID 17279347 DOI: 10.1007/s00109-007-0156-7 |
0.345 |
|
| 2006 |
Dasilva KA, Aubert I, McLaurin J. Vaccine development for Alzheimer's disease. Current Pharmaceutical Design. 12: 4283-93. PMID 17105428 DOI: 10.2174/138161206778793001 |
0.33 |
|
| 2006 |
McLaurin J, Kierstead ME, Brown ME, Hawkes CA, Lambermon MH, Phinney AL, Darabie AA, Cousins JE, French JE, Lan MF, Chen F, Wong SS, Mount HT, Fraser PE, Westaway D, et al. Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. Nature Medicine. 12: 801-8. PMID 16767098 DOI: 10.1038/Nm1423 |
0.374 |
|
| 2005 |
Fenili D, McLaurin J. Cholesterol and apoe: a target for Alzheimer's disease therapeutics. Current Drug Targets. Cns and Neurological Disorders. 4: 553-67. PMID 16266288 DOI: 10.2174/156800705774322085 |
0.325 |
|
| 2004 |
Dasilva KA, McLaurin J. New therapeutic approaches for Alzheimer's disease. Discovery Medicine. 4: 384-9. PMID 20704936 |
0.377 |
|
| 2004 |
Gelinas DS, DaSilva K, Fenili D, St George-Hyslop P, McLaurin J. Immunotherapy for Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 14657-62. PMID 15297619 DOI: 10.1073/pnas.0404866101 |
0.306 |
|
| 2002 |
Westaway D, Janus C, Johnson H, Chishti MA, McLaurin J, Mathews P, Jiang Y, Schmidt SD, Horne P, French J, Nixon RA, Mercken M, Fraser PE, Bergeron C, Carlson GA, et al. Aβ-immunization reduces learning impairment and amyloid plaque burden in an animal model of Alzheimer's disease European Neuropsychopharmacology. 12: 98. DOI: 10.1016/S0924-977X(02)80030-X |
0.323 |
|
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