Thomas Fath - Publications

Affiliations: 
Macquarie University, Macquarie Park, New South Wales, Australia 

21/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Prikas E, Paric E, Asih PR, Stefanoska K, Stefen H, Fath T, Poljak A, Ittner A. Tau target identification reveals NSF-dependent effects on AMPA receptor trafficking and memory formation. The Embo Journal. 41: e10242. PMID 35993331 DOI: 10.15252/embj.2021110242  0.437
2021 Chaichim C, Tomanic T, Stefen H, Paric E, Gamaroff L, Suchowerska AK, Gunning PW, Ke YD, Fath T, Power J. Overexpression of Tropomyosin Isoform Tpm3.1 Does Not Alter Synaptic Function in Hippocampal Neurons. International Journal of Molecular Sciences. 22. PMID 34502205 DOI: 10.3390/ijms22179303  0.508
2018 Gray KT, Stefen H, Ly TNA, Keller CJ, Colpan M, Wayman GA, Pate E, Fath T, Kostyukova AS. Tropomodulin's Actin-Binding Abilities Are Required to Modulate Dendrite Development. Frontiers in Molecular Neuroscience. 11: 357. PMID 30356860 DOI: 10.3389/fnmol.2018.00357  0.533
2018 Stefen H, Hassanzadeh-Barforoushi A, Brettle M, Fok S, Suchowerska AK, Tedla N, Barber T, Warkiani ME, Fath T. A Novel Microfluidic Device-Based Neurite Outgrowth Inhibition Assay Reveals the Neurite Outgrowth-Promoting Activity of Tropomyosin Tpm3.1 in Hippocampal Neurons. Cellular and Molecular Neurobiology. PMID 30218404 DOI: 10.1007/s10571-018-0620-7  0.329
2017 Suchowerska AK, Fok S, Stefen H, Gunning PW, Hardeman EC, Power J, Fath T. Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain. Frontiers in Cellular Neuroscience. 11: 421. PMID 29311841 DOI: 10.3389/Fncel.2017.00421  0.693
2017 Patel S, Fok SYY, Stefen H, Tomanić T, Parić E, Herold R, Brettle M, Djordjevic A, Fath T. Functional characterisation of filamentous actin probe expression in neuronal cells. Plos One. 12: e0187979. PMID 29145435 DOI: 10.1371/journal.pone.0187979  0.394
2017 Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, Hoven JV, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, et al. Tau exacerbates excitotoxic brain damage in an animal model of stroke. Nature Communications. 8: 473. PMID 28883427 DOI: 10.1038/S41467-017-00618-0  0.315
2017 Gormal RS, Valmas N, Fath T, Meunier FA. A role for tropomyosins in activity-dependent bulk endocytosis? Molecular and Cellular Neurosciences. PMID 28545680 DOI: 10.1016/j.mcn.2017.04.003  0.425
2017 Gray KT, Kostyukova AS, Fath T. Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function. Molecular and Cellular Neurosciences. PMID 28433463 DOI: 10.1016/j.mcn.2017.04.002  0.462
2016 Brettle M, Patel S, Fath T. Tropomyosins in the healthy and diseased nervous system. Brain Research Bulletin. PMID 27298153 DOI: 10.1016/j.brainresbull.2016.06.004  0.56
2016 Stefen H, Chaichim C, Power J, Fath T. Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease. Neural Plasticity. 2016: 2371970. PMID 27127658 DOI: 10.1155/2016/2371970  0.506
2016 Gray KT, Suchowerska AK, Bland T, Colpan M, Wayman G, Fath T, Kostyukova AS. Tropomodulin isoforms utilize specific binding functions to modulate dendrite development. Cytoskeleton (Hoboken, N.J.). PMID 27126680 DOI: 10.1002/Cm.21304  0.419
2016 An H, Brettle M, Lee T, Heng B, Lim CK, Guillemin GJ, Lord MS, Klotzsch E, Geczy CL, Bryant K, Fath T, Tedla N. Soluble LILRA3 promotes neurite outgrowth and synapses formation through high affinity interaction with Nogo 66. Journal of Cell Science. PMID 26826187 DOI: 10.1242/jcs.182006  0.34
2015 Brettle M, Suchowerska AK, Chua SW, Ittner LM, Fath T. Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons Neuroscience Letters. 609: 223-228. PMID 26499959 DOI: 10.1016/j.neulet.2015.09.034  0.304
2015 Jalilian I, Heu C, Cheng H, Freittag H, Desouza M, Stehn JR, Bryce NS, Whan RM, Hardeman EC, Fath T, Schevzov G, Gunning PW. Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton. Plos One. 10: e0126214. PMID 25978408 DOI: 10.1371/journal.pone.0126214  0.345
2013 Fath T. Tropomodulins and tropomyosins - organizers of cellular microcompartments. Biomolecular Concepts. 4: 89-101. PMID 25436568 DOI: 10.1515/bmc-2012-0037  0.309
2012 Schevzov G, Curthoys NM, Gunning PW, Fath T. Functional diversity of actin cytoskeleton in neurons and its regulation by tropomyosin. International Review of Cell and Molecular Biology. 298: 33-94. PMID 22878104 DOI: 10.1016/B978-0-12-394309-5.00002-X  0.467
2011 Guven K, Gunning P, Fath T. TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses. Bioarchitecture. 1: 284-289. PMID 22545181 DOI: 10.4161/bioa.1.6.19336  0.682
2011 Fath T, Fischer RS, Dehmelt L, Halpain S, Fowler VM. Tropomodulins are negative regulators of neurite outgrowth. European Journal of Cell Biology. 90: 291-300. PMID 21146252 DOI: 10.1016/J.Ejcb.2010.10.014  0.416
2010 Fath T, Agnes Chan YK, Vrhovski B, Clarke H, Curthoys N, Hook J, Lemckert F, Schevzov G, Tam P, Watson CM, Khoo PL, Gunning P. New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. European Journal of Cell Biology. 89: 489-98. PMID 20223554 DOI: 10.1016/j.ejcb.2009.11.028  0.308
2008 Schevzov G, Fath T, Vrhovski B, Vlahovich N, Rajan S, Hook J, Joya JE, Lemckert F, Puttur F, Lin JJ, Hardeman EC, Wieczorek DF, O'Neill GM, Gunning PW. Divergent regulation of the sarcomere and the cytoskeleton. The Journal of Biological Chemistry. 283: 275-83. PMID 17951248 DOI: 10.1074/Jbc.M704392200  0.35
Low-probability matches (unlikely to be authored by this person)
2011 Schevzov G, Whittaker SP, Fath T, Lin JJ, Gunning PW. Tropomyosin isoforms and reagents. Bioarchitecture. 1: 135-164. PMID 22069507 DOI: 10.4161/bioa.1.4.17897  0.297
2021 Tomanić T, Martin C, Stefen H, Parić E, Gunning P, Fath T. Deletion of the Actin-Associated Tropomyosin Leads to Reduced Cell Complexity in Cultured Hippocampal Neurons-New Insights into the Role of the C-Terminal Region of Tpm3.1. Cells. 10. PMID 33807093 DOI: 10.3390/cells10030715  0.295
2017 Fath T, Kostyukova AS, Foa L. Special issue on 'Cytoskeleton-dependent regulation of neuronal network formation'. Molecular and Cellular Neurosciences. 84: 1-3. PMID 29103565 DOI: 10.1016/j.mcn.2017.09.008  0.289
2020 Abouelezz A, Stefen H, Segerstråle M, Micinski D, Minkeviciene R, Lahti L, Hardeman EC, Gunning PW, Hoogenraad CC, Taira T, Fath T, Hotulainen P. Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment. Iscience. 23: 101053. PMID 32344377 DOI: 10.1016/j.isci.2020.101053  0.288
2018 Martin AD, Chua SW, Au CG, Stefen H, Przybyla M, Lin Y, Bertz J, Thordarson P, Fath T, Ke YD, Ittner LM. Peptide nanofiber substrates for long-term culturing of primary neurons. Acs Applied Materials & Interfaces. PMID 29979564 DOI: 10.1021/acsami.8b07560  0.264
2014 Curthoys NM, Freittag H, Connor A, Desouza M, Brettle M, Poljak A, Hall A, Hardeman E, Schevzov G, Gunning PW, Fath T. Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells. Molecular and Cellular Neurosciences. 58: 11-21. PMID 24211701 DOI: 10.1016/j.mcn.2013.10.011  0.264
2021 Lee WS, Tan DC, Deng Y, van Hummel A, Ippati S, Stevens C, Carmona-Mora P, Ariawan D, Hou L, Stefen H, Tomanic T, Bi M, Tomasetig F, Martin A, Fath T, et al. Syntaxins 6 and 8 facilitate tau into secretory pathways. The Biochemical Journal. PMID 33769438 DOI: 10.1042/BCJ20200664  0.26
2009 Brandt R, Gergou A, Wacker I, Fath T, Hutter H. A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau. Neurobiology of Aging. 30: 22-33. PMID 17590239 DOI: 10.1016/J.Neurobiolaging.2007.05.011  0.246
2011 Hook J, Lemckert F, Schevzov G, Fath T, Gunning P. Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability. Bioarchitecture. 1: 49-59. PMID 21866263 DOI: 10.4161/bioa.1.1.15172  0.226
2021 Ippati S, Deng Y, van der Hoven J, Heu C, van Hummel A, Chua SW, Paric E, Chan G, Feiten A, Fath T, Ke YD, Haass NK, Ittner LM. Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33737393 DOI: 10.1073/pnas.2011876118  0.225
2009 Fath T, Ke YD, Gunning P, Götz J, Ittner LM. Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols. 4: 78-85. PMID 19131959 DOI: 10.1038/Nprot.2008.199  0.22
2016 Couttas TA, Kain N, Suchowerska AK, Quek LE, Turner N, Fath T, Garner B, Don AS. Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease. Neurobiology of Aging. 43: 89-100. PMID 27255818 DOI: 10.1016/j.neurobiolaging.2016.03.027  0.218
2019 Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, et al. Sphingosine kinase 2 potentiates amyloid deposition but protects against hippocampal volume loss and demyelination in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31641049 DOI: 10.1523/JNEUROSCI.0524-19.2019  0.215
2019 Tran C, Heng B, Teo JD, Humphrey SJ, Qi Y, Couttas TA, Stefen H, Brettle M, Fath T, Guillemin GJ, Don AS. Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes. Journal of Neurochemistry. PMID 31742704 DOI: 10.1111/jnc.14917  0.209
2024 Xu Z, Angstmann CN, Wu Y, Stefen H, Parić E, Fath T, Curmi PMG. Location of the axon initial segment assembly can be predicted from neuronal shape. Iscience. 27: 109264. PMID 38450155 DOI: 10.1016/j.isci.2024.109264  0.204
2002 Fath T, Eidenmüller J, Brandt R. Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9733-41. PMID 12427828  0.196
2013 Stehn JR, Haass NK, Bonello T, Desouza M, Kottyan G, Treutlein H, Zeng J, Nascimento PR, Sequeira VB, Butler TL, Allanson M, Fath T, Hill TA, McCluskey A, Schevzov G, et al. A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells. Cancer Research. 73: 5169-82. PMID 23946473 DOI: 10.1158/0008-5472.CAN-12-4501  0.195
2020 Sytnyk V, Fath T. Editorial: From Structure to Function - The Interplay Between Cell Adhesion Molecules and the Cytoskeleton. Frontiers in Cell and Developmental Biology. 8: 104. PMID 32158756 DOI: 10.3389/Fcell.2020.00104  0.194
2018 Stefen H, Suchowerska AK, Chen BJ, Brettle M, Kuschelewski J, Gunning PW, Janitz M, Fath T. Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells. Febs Open Bio. 8: 570-583. PMID 29632810 DOI: 10.1002/2211-5463.12386  0.186
2018 Fröhlich D, Suchowerska AK, Voss C, He R, Wolvetang E, von Jonquieres G, Simons C, Fath T, Housley GD, Klugmann M. Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain. Frontiers in Molecular Neuroscience. 11: 81. PMID 29615866 DOI: 10.3389/Fnmol.2018.00081  0.172
2015 Schevzov G, Kee AJ, Wang B, Sequeira VB, Hook J, Coombes JD, Lucas CA, Stehn JR, Musgrove EA, Cretu A, Assoian R, Fath T, Hanoch T, Seger R, Pleines I, et al. Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments. Molecular Biology of the Cell. 26: 2475-90. PMID 25971798 DOI: 10.1091/Mbc.E14-10-1453  0.156
2019 Brettle M, Stefen H, Djordjevic A, Fok SYY, Chan JW, van Hummel A, van der Hoven J, Przybyla M, Volkerling A, Ke YD, Delerue F, Ittner LM, Fath T. Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice. Frontiers in Molecular Neuroscience. 12: 231. PMID 31611772 DOI: 10.3389/fnmol.2019.00231  0.155
2008 Ittner LM, Fath T, Ke YD, Bi M, van Eersel J, Li KM, Gunning P, Götz J. Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 105: 15997-6002. PMID 18832465 DOI: 10.1073/Pnas.0808084105  0.149
2020 Dobson-Stone C, Hallupp M, Shahheydari H, Ragagnin AMG, Chatterton Z, Carew-Jones F, Shepherd CE, Stefen H, Paric E, Fath T, Thompson EM, Blumbergs P, Short CL, Field CD, Panegyres PK, et al. CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 32185393 DOI: 10.1093/Brain/Awaa039  0.147
2008 Götz J, David D, Hoerndli F, Ke YD, Schonrock N, Wiesner A, Fath T, Bokhari L, Lim YA, Deters N, Ittner LM. Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response. Neuro-Degenerative Diseases. 5: 179-81. PMID 18322384 DOI: 10.1159/000113696  0.145
2021 Ariawan D, Au C, Paric E, Fath T, Ke YD, Kassiou M, van Eersel J, Ittner LM. The Nature of Diamino Linker and Halogen Bonding Define Selectivity of Pyrrolopyrimidine-Based LIMK1 Inhibitors. Frontiers in Chemistry. 9: 781213. PMID 34966720 DOI: 10.3389/fchem.2021.781213  0.142
2019 Martin AD, Wojciechowski JP, Du EY, Rawal A, Stefen H, Au CG, Hou L, Cranfield CG, Fath T, Ittner LM, Thordarson P. Decoupling the effects of hydrophilic and hydrophobic moieties at the neuron-nanofibre interface. Chemical Science. 11: 1375-1382. PMID 34123262 DOI: 10.1039/c9sc05686f  0.141
2023 Fath T, Sytnyk V, Martínez-Mármol R. '10th cell architecture in development and disease (CADD)': Meeting report. Cytoskeleton (Hoboken, N.J.). PMID 38102923 DOI: 10.1002/cm.21815  0.137
2016 Tate ML, Fath T. The Only Constant Is Change: Next Generation Materials and Medical Device Design for Physical and Mental Health. Advanced Healthcare Materials. PMID 27281701 DOI: 10.1002/adhm.201600437  0.118
2016 Fröhlich D, Suchowerska AK, Spencer ZH, von Jonquieres G, Klugmann CB, Bongers A, Delerue F, Stefen H, Ittner LM, Fath T, Housley GD, Klugmann M. In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiology of Disease. PMID 27816769 DOI: 10.1016/J.Nbd.2016.10.008  0.117
2018 Nguyen HL, Ruhoff AM, Fath T, Jones NM. Hypoxic postconditioning enhances functional recovery following endothelin-1 induced middle cerebral artery occlusion in conscious rats. Experimental Neurology. PMID 29778441 DOI: 10.1016/j.expneurol.2018.05.018  0.098
2017 Tonkin RS, Bowles C, Perera CJ, Keating BA, Makker PGS, Duffy SS, Lees JG, Tran C, Don A, Fath T, Liu L, O'Carroll SJ, Nicholson LFB, Green CR, Gorrie C, et al. Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice. Experimental Neurology. PMID 29055716 DOI: 10.1016/j.expneurol.2017.10.016  0.076
2018 Turner N, Lim XY, Toop HD, Osborne B, Brandon AE, Taylor EN, Fiveash CE, Govindaraju H, Teo JD, McEwen HP, Couttas TA, Butler SM, Das A, Kowalski GM, Bruce CR, ... ... Fath T, et al. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nature Communications. 9: 3165. PMID 30131496 DOI: 10.1038/S41467-018-05613-7  0.067
2012 Dale RC, Merheb V, Pillai S, Wang D, Cantrill L, Murphy TK, Ben-Pazi H, Varadkar S, Aumann TD, Horne MK, Church AJ, Fath T, Brilot F. Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders. Brain : a Journal of Neurology. 135: 3453-68. PMID 23065479 DOI: 10.1093/brain/aws256  0.013
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