| Year |
Citation |
Score |
| 2011 |
Khojasteh SC, Prabhu S, Kenny JR, Halladay JS, Lu AY. Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity. European Journal of Drug Metabolism and Pharmacokinetics. 36: 1-16. PMID 21336516 DOI: 10.1007/s13318-011-0024-2 |
0.333 |
|
| 2009 |
Shou M, Lu AY. Antibodies as a probe in cytochrome P450 research. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 925-31. PMID 19196844 DOI: 10.1124/Dmd.108.025718 |
0.463 |
|
| 2008 |
Ma Q, Lu AY. The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters. Current Drug Metabolism. 9: 374-83. PMID 18537574 DOI: 10.2174/138920008784746337 |
0.373 |
|
| 2007 |
Ma Q, Lu AY. CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1009-16. PMID 17431034 DOI: 10.1124/Dmd.107.015826 |
0.347 |
|
| 2005 |
Tang W, Wang RW, Lu AY. Utility of recombinant cytochrome p450 enzymes: a drug metabolism perspective. Current Drug Metabolism. 6: 503-17. PMID 16248842 DOI: 10.2174/138920005774330602 |
0.503 |
|
| 2005 |
Tang C, Lin JH, Lu AY. Metabolism-based drug-drug interactions: what determines individual variability in cytochrome P450 induction? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 603-13. PMID 15673596 DOI: 10.1124/Dmd.104.003236 |
0.408 |
|
| 2004 |
He XY, Shen J, Ding X, Lu AY, Hong JY. Identification of critical amino acid residues of human CYP2A13 for the metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific carcinogen. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1516-21. PMID 15333516 DOI: 10.1124/Dmd.104.001370 |
0.355 |
|
| 2003 |
Lu AY, Wang RW, Lin JH. Cytochrome P450 in vitro reaction phenotyping: a re-evaluation of approaches used for P450 isoform identification. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 345-50. PMID 12642457 |
0.341 |
|
| 1998 |
Lu AY. The 1996 Bernard B. Brodie lecture: A journey in cytochrome P450 and drug metabolism research. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 1168-73. PMID 9860921 |
0.306 |
|
| 1998 |
Lin JH, Lu AY. Inhibition and induction of cytochrome P450 and the clinical implications. Clinical Pharmacokinetics. 35: 361-90. PMID 9839089 DOI: 10.2165/00003088-199835050-00003 |
0.305 |
|
| 1995 |
Cui K, Lu AY, Yang CS. Subunit functional studies of NAD(P)H:quinone oxidoreductase with a heterodimer approach. Proceedings of the National Academy of Sciences of the United States of America. 92: 1043-7. PMID 7862630 DOI: 10.1073/Pnas.92.4.1043 |
0.315 |
|
| 1995 |
Newton DJ, Wang RW, Lu AY. Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 23: 154-8. PMID 7720520 |
0.385 |
|
| 1991 |
Wang RW, Kari PH, Lu AY, Thomas PE, Guengerich FP, Vyas KP. Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes. Archives of Biochemistry and Biophysics. 290: 355-61. PMID 1929403 DOI: 10.1016/0003-9861(91)90551-S |
0.564 |
|
| 1990 |
Vyas KP, Kari PH, Wang RW, Lu AY. Biotransformation of lovastatin--III. Effect of cimetidine and famotidine on in vitro metabolism of lovastatin by rat and human liver microsomes. Biochemical Pharmacology. 39: 67-73. PMID 2297361 |
0.33 |
|
| 1990 |
Ma Q, Wang R, Yang CS, Lu AY. Expression of mammalian DT-diaphorase in Escherichia coli: purification and characterization of the expressed protein. Archives of Biochemistry and Biophysics. 283: 311-7. PMID 1703398 DOI: 10.1016/0003-9861(90)90648-I |
0.305 |
|
| 1989 |
Thomas PE, Lu AY, Ryan D, West S, Levin W. Specificity of antisera directed against rat liver cytochrome P-448. Life Sciences. 15: 1475-83. PMID 4549989 DOI: 10.1016/0024-3205(74)90122-2 |
0.561 |
|
| 1989 |
Cheng KC, Wang RW, Lu AY. NADPH-cytochrome P-450 reductase is not a component of the liver microsomal steroid 5-alpha reductase. Biochemical and Biophysical Research Communications. 165: 590-4. PMID 2512918 |
0.397 |
|
| 1988 |
Wang RW, Miwa GT, Argenbright LS, Lu AY. In vitro studies on the interaction of famotidine with liver microsomal cytochrome P-450. Biochemical Pharmacology. 37: 3049-53. PMID 2899433 |
0.45 |
|
| 1986 |
Patten CJ, Ning SM, Lu AY, Yang CS. Acetone-inducible cytochrome P-450: purification, catalytic activity, and interaction with cytochrome b5. Archives of Biochemistry and Biophysics. 251: 629-38. PMID 3800390 DOI: 10.1016/0003-9861(86)90373-5 |
0.464 |
|
| 1986 |
Williams JB, Lu AY, Cameron RG, Pickett CB. Rat liver NAD(P)H:quinone reductase. Construction of a quinone reductase cDNA clone and regulation of quinone reductase mRNA by 3-methylcholanthrene and in persistent hepatocyte nodules induced by chemical carcinogens. The Journal of Biological Chemistry. 261: 5524-8. PMID 3007509 |
0.396 |
|
| 1985 |
Miwa GT, Harada N, Lu AY. Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions: full expression of the intrinsic isotope effect during the O-deethylation of 7-ethoxycoumarin by liver microsomes from 3-methylcholanthrene-induced hamsters. Archives of Biochemistry and Biophysics. 239: 155-62. PMID 4004255 |
0.336 |
|
| 1984 |
Wislocki PG, Bagan ES, Vandenheuvel WJ, Walker RW, Alvaro RF, Arison BH, Lu AY, Wolf FJ. Drug residue formation from ronidazole, a 5-nitroimidazole. V. Cysteine adducts formed upon reduction of ronidazole by dithionite or rat liver enzymes in the presence of cysteine. Chemico-Biological Interactions. 49: 13-25. PMID 6722933 |
0.366 |
|
| 1984 |
Harada N, Miwa GT, Walsh JS, Lu AY. Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions. Evidence for the irreversible formation of an activated oxygen intermediate of cytochrome P-448. The Journal of Biological Chemistry. 259: 3005-10. PMID 6699004 |
0.358 |
|
| 1984 |
Miwa GT, Lu AY. The association of cytochrome P-450 and NADPH-cytochrome P-450 reductase in phospholipid membranes. Archives of Biochemistry and Biophysics. 234: 161-6. PMID 6435533 |
0.371 |
|
| 1984 |
Pickett CB, Williams JB, Lu AY, Cameron RG. Regulation of glutathione transferase and DT-diaphorase mRNAs in persistent hepatocyte nodules during chemical hepatocarcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 81: 5091-5. PMID 6433344 DOI: 10.1073/Pnas.81.16.5091 |
0.344 |
|
| 1984 |
Dahlin DC, Miwa GT, Lu AY, Nelson SD. N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen. Proceedings of the National Academy of Sciences of the United States of America. 81: 1327-31. PMID 6424115 DOI: 10.1073/Pnas.81.5.1327 |
0.436 |
|
| 1984 |
Chiu SH, Sestokas E, Taub R, Smith JL, Arison B, Lu AY. The metabolism of avermectin-H2B1a and -H2B1b by pig liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 12: 464-9. PMID 6148214 |
0.318 |
|
| 1983 |
Pickett CB, Jeter RL, Wang R, Lu AY. Coordinate induction of multiple mRNAs specific for rat liver phenobarbital-inducible cytochromes P-450. Archives of Biochemistry and Biophysics. 225: 854-60. PMID 6194754 DOI: 10.1016/0003-9861(83)90098-X |
0.376 |
|
| 1982 |
Ortiz de Montellano PR, Mico BA, Mathews JM, Kunze KL, Miwa GT, Lu AY. Selective inactivation of cytochrome P-450 isozymes by suicide substrates. Archives of Biochemistry and Biophysics. 210: 717-28. PMID 7305355 DOI: 10.1016/0003-9861(81)90239-3 |
0.307 |
|
| 1982 |
Miwa GT, West SB, Walsh JS, Wolf FJ, Lu AY. Drug residue formation from ronidazole, a 5-nitroimidazole. III. Studies on the mechanism of protein alkylation in vitro. Chemico-Biological Interactions. 41: 297-312. PMID 6809347 DOI: 10.1016/0009-2797(82)90107-7 |
0.306 |
|
| 1982 |
West SB, Wislocki PG, Wolf FJ, Lu AY. Drug residue formation from ronidazole, a 5-nitroimidazole. II. Involvement of microsomal NADPH-cytochrome P-450 reductase in protein alkylation in vitro. Chemico-Biological Interactions. 41: 281-96. PMID 6809346 DOI: 10.1016/0009-2797(82)90106-5 |
0.425 |
|
| 1982 |
West SB, Wislocki PG, Fiorentini KM, Alvaro R, Wolf FJ, Lu AY. Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation. Chemico-Biological Interactions. 41: 265-79. PMID 6809345 DOI: 10.1016/0009-2797(82)90105-3 |
0.338 |
|
| 1982 |
Miwa GT, Lu AY. Studies on the stimulation of cytochrome P-450-dependent monooxygenase activity by dilauroylphosphatidylcholine. Archives of Biochemistry and Biophysics. 211: 454-8. PMID 6795999 DOI: 10.1016/0003-9861(81)90477-X |
0.314 |
|
| 1982 |
Pickett CB, Telakowski-Hopkins CA, Donohue AM, Lu AY, Hales BF. Differential induction of rat hepatic cytochrome P-448 and glutathione S-transferase B messenger RNAs by 3-methylcholanthrene. Biochemical and Biophysical Research Communications. 104: 611-9. PMID 6176233 DOI: 10.1016/0006-291X(82)90681-7 |
0.365 |
|
| 1980 |
Lu AY, Miwa GT. Molecular properties and biological functions of microsomal epoxide hydrase Annual Review of Pharmacology and Toxicology. 20: 513-531. PMID 6992704 DOI: 10.1146/Annurev.Pa.20.040180.002501 |
0.422 |
|
| 1980 |
Lu AY, Wislocki PG, West SB, Miwa GT. Activating enzymes: multiple monooxygenase forms with different substrate preferences as related to toxic effects. Archives of Toxicology. Supplement. = Archiv Fur Toxikologie. Supplement. 3: 161-9. PMID 6930941 DOI: 10.1007/978-3-642-67389-4_11 |
0.385 |
|
| 1980 |
Wolff T, Greim H, Huang MT, Miwa GT, Lu AY. Aldrin epoxidation catalyzed by purified rat-liver cytochrome P-450 and P-448. High selectivity for cytochrome P-450 European Journal of Biochemistry. 111: 545-551. PMID 6780342 DOI: 10.1111/j.1432-1033.1980.tb04970.x |
0.505 |
|
| 1980 |
Lu AY, Miwa GT, West SB, Hodshon BJ, Garland WA. Kinetic isotope effects in cytochrome P-450-catalyzed oxidation reactions. II. Interactions of cytochrome P-450 with substrates and NADPH-cytochrome C reductase Advances in Experimental Medicine and Biology. 132: 95-108. PMID 6775516 DOI: 10.1007/978-1-4757-1419-7_11 |
0.362 |
|
| 1979 |
West SB, Huang MT, Miwa GT, Lu AY. A simple and rapid procedure for the purification of phenobarbital-inducible cytochrome P-450 from rat liver microsomes. Archives of Biochemistry and Biophysics. 193: 42-50. PMID 453857 DOI: 10.1016/0003-9861(79)90006-7 |
0.48 |
|
| 1978 |
Huang MT, Miwa GT, Lu AY. Induction of rat liver cytosol methyl red azo-reductase by 3-methylcholanthrene assayed by a sensitive fluorometric method. Biochemical and Biophysical Research Communications. 83: 1253-9. PMID 697858 DOI: 10.1016/0006-291X(78)91356-6 |
0.43 |
|
| 1978 |
Lu AY, Levin W. Purification and assay of liver microsomal epoxide hydrase. Methods in Enzymology. 52: 193-200. PMID 672628 DOI: 10.1016/S0076-6879(78)52021-1 |
0.392 |
|
| 1978 |
Ryan D, Lu AY, Levin W. Purification of cytochrome P-450 and P-448 from rat liver microsomes. Methods in Enzymology. 52: 117-23. PMID 672622 DOI: 10.1016/S0076-6879(78)52013-2 |
0.553 |
|
| 1978 |
Levin W, Lu AY, Thomas PE, Ryan D, Kizer DE, Griffin MJ. Identification of epoxide hydrase as the preneoplastic antigen in rat liver hyperplastic nodules. Proceedings of the National Academy of Sciences of the United States of America. 75: 3240-3. PMID 210455 DOI: 10.1073/Pnas.75.7.3240 |
0.452 |
|
| 1978 |
Miwa GT, Levin W, Thomas PE, Lu AY. The direct oxidation of ethanol by a catalase- and alcohol dehydrogenase-free reconstituted system containing cytochrome P-4501. Archives of Biochemistry and Biophysics. 187: 464-75. PMID 27144 DOI: 10.1016/0003-9861(78)90058-9 |
0.444 |
|
| 1977 |
Lu AY, Ryan D, Kawalek J, Thomas P, West SB, Huang MT, Levin W. Multiplicity of liver microsomal cytochrome P-450: separation, purification and characterization. Biochemical Society Transactions. 4: 169-72. PMID 1001627 DOI: 10.1042/Bst0040169 |
0.555 |
|
| 1977 |
Kawalek JC, Levin W, Ryan D, Lu AY. Role of sulfhydryl gropus in the hydroxylation of benzo[a]pyrene by purified rat and rabbit cytochrome P-448. Archives of Biochemistry and Biophysics. 183: 732-41. PMID 921285 DOI: 10.1016/0003-9861(77)90407-6 |
0.535 |
|
| 1977 |
Cooper DY, Schleyer H, Rosenthal O, Levin W, Lu AY, Kuntzman R, Conney AH. Inhibition by CO of hepatic benzo[a]pyrene hydroxylation and its reversal by monochromatic light. European Journal of Biochemistry / Febs. 74: 69-75. PMID 856576 DOI: 10.1111/J.1432-1033.1977.Tb11367.X |
0.516 |
|
| 1977 |
Huang MT, West SB, Lu AY. Liver microsomal DT diaphorase: noninvolvement in hydroxylation of benzo(a)pyrene. Biochemical and Biophysical Research Communications. 74: 1355-61. PMID 402917 DOI: 10.1016/0006-291X(77)90591-5 |
0.543 |
|
| 1977 |
West SB, Lu AY. Liver microsomal electron transport systems. Properties of a reconstituted, NADH-mediated benzo[a]pyrene hydroxylation system. Archives of Biochemistry and Biophysics. 182: 369-78. PMID 197888 DOI: 10.1016/0003-9861(77)90517-3 |
0.395 |
|
| 1976 |
Holder GM, Yagi H, Jerina DM, Levin W, Lu AY, Conney AH. Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice. Archives of Biochemistry and Biophysics. 170: 557-66. PMID 1190779 DOI: 10.1016/0003-9861(75)90151-4 |
0.407 |
|
| 1975 |
Lu AY, Levin W, Kuntzman R. Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. VII. Stimulation of benzphetamine N-demethylation by lipid and detergent. Biochemical and Biophysical Research Communications. 60: 266-72. PMID 4371318 DOI: 10.1016/0006-291X(74)90200-9 |
0.493 |
|
| 1975 |
Lu AY, Levin W, Selander H, Jerina DM. Liver microsomal electron transport systems. III. The involvement of cytochrome b5 in the NADPH-supported cytochrome P-450-dependent hydroxylation of chlorobenzene. Biochemical and Biophysical Research Communications. 61: 1348-55. PMID 4156173 DOI: 10.1016/S0006-291X(74)80432-8 |
0.518 |
|
| 1975 |
Lu AY, Levin W, West S, Jacobson M, Ryan D, Kuntzman R, Conney AH. The role of cytochrome P-450 and P-448 in drug and steroid hydroxylations. Annals of the New York Academy of Sciences. 212: 156-74. PMID 4155922 DOI: 10.1111/J.1749-6632.1973.Tb47594.X |
0.484 |
|
| 1975 |
Levin W, Lu AY, Ryan D, West S, Kuntzman R, Conney AH. Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes Advances in Experimental Medicine and Biology. 58: 1-24. PMID 808108 DOI: 10.1007/978-1-4615-9026-2_1 |
0.583 |
|
| 1975 |
Lu AY, Levin W, West SB, Vore M, Ryan D, Kuntzman R, Conney AH. Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system Advances in Experimental Medicine and Biology. 58: 447-466. PMID 239545 DOI: 10.1007/978-1-4615-9026-2_31 |
0.356 |
|
| 1975 |
Stern JO, Peisach E, Peisach J, Blumberg WE, Lu AY, Ryan WD, Levin W, West S. Studies on the spin state of 3-methylcholanthrene induced cytochrome P-450 from rat liver. Advances in Experimental Medicine and Biology. 58: 189-202. PMID 168749 DOI: 10.1007/978-1-4615-9026-2_13 |
0.479 |
|
| 1975 |
Hrycay EG, Jonen HG, Levin W, Lu AY. Reconstitution of the reduced nicotinamide adenine dinucleotide phosphate- and reduced nicotinamide adenine dinucleotide-peroxidase activities from solubilized components of rat liver microsomes. Archives of Biochemistry and Biophysics. 166: 145-51. PMID 164823 DOI: 10.1016/0003-9861(75)90374-4 |
0.601 |
|
| 1974 |
Holder G, Yagi H, Dansette P, Jerina DM, Levin W, Lu AY, Conney AH. Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proceedings of the National Academy of Sciences of the United States of America. 71: 4356-4360. PMID 4530987 DOI: 10.1073/Pnas.71.11.4356 |
0.419 |
|
| 1974 |
Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7 |
0.327 |
|
| 1974 |
West SB, Levin W, Ryan D, Vore M, Lu AY. Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system. Biochemical and Biophysical Research Communications. 58: 516-522. PMID 4366168 DOI: 10.1016/0006-291X(74)90395-7 |
0.51 |
|
| 1974 |
Vore M, Hamilton JG, Lu AY. Organic solvent extraction of liver microsomal lipid. I. The requirement of lipid for 3,4-benzpyrene hydroxylase. Biochemical and Biophysical Research Communications. 56: 1038-44. PMID 4151167 DOI: 10.1016/S0006-291X(74)80293-7 |
0.412 |
|
| 1974 |
Levin W, Lu AY, Jacobson M, Kuntzman R, Poyer JL, McCay PB. Lipid peroxidation and the degradation of cytochrome P-450 heme. Archives of Biochemistry and Biophysics. 158: 842-52. PMID 4150126 DOI: 10.1016/0003-9861(73)90580-8 |
0.542 |
|
| 1974 |
Lu AY, Levin W. The resolution and reconstitution of the liver microsomal hydroxylation system Biochimica Et Biophysica Acta (Bba) - Reviews On Biomembranes. 344: 205-240. DOI: 10.1016/0304-4157(74)90004-5 |
0.428 |
|
| 1973 |
Levin W, Lu AY, Ryan D, West S, Kuntzman R, Conney AH. Partial purification and properties of cytochromes P-450 and P-448 from rat liver microsomes. Archives of Biochemistry and Biophysics. 153: 543-53. PMID 4662099 DOI: 10.1016/0003-9861(72)90373-6 |
0.572 |
|
| 1973 |
Oesch F, Jerina DM, Daly JW, Lu AY, Kuntzman R, Conney AH. A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. Archives of Biochemistry and Biophysics. 153: 62-7. PMID 4650623 DOI: 10.1016/0003-9861(72)90420-1 |
0.529 |
|
| 1973 |
West SB, Lu AY. Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. V. Competition between cytochromes P-450 and P-448 for reductase in 3,4-benzpyrene hydroxylation. Archives of Biochemistry and Biophysics. 153: 298-303. PMID 4650614 DOI: 10.1016/0003-9861(72)90448-1 |
0.551 |
|
| 1973 |
Lu AY, Jacobson M, Levin W, West SB, Kuntzman R. Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IV. Hydroxylation of aniline. Archives of Biochemistry and Biophysics. 153: 294-7. PMID 4650613 DOI: 10.1016/0003-9861(72)90447-X |
0.607 |
|
| 1973 |
Stern JO, Peisach J, Blumberg WE, Lu AY, Levin W. A low-temperature EPR study of partially purified, soluble ferric cytochromes P-450 and P-448 from rat liver microsomes. Archives of Biochemistry and Biophysics. 156: 404-13. PMID 4352418 DOI: 10.1016/0003-9861(73)90289-0 |
0.497 |
|
| 1973 |
Lu AY, Somogyi A, West S, Kuntzman R, Conney AH. Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes. Archives of Biochemistry and Biophysics. 152: 457-62. PMID 4344124 DOI: 10.1016/0003-9861(72)90239-1 |
0.469 |
|
| 1972 |
Kuntzman R, Lu AY, West S, Jacobson M, Conney AH. The importance of cytochrome P-450 and P-448 in determining the specificity of the reconstituted liver microsomal hydroxylation system. Chemico-Biological Interactions. 3: 287-8. PMID 5133004 DOI: 10.1016/0009-2797(71)90063-9 |
0.573 |
|
| 1972 |
Jacobson M, Lu AY, Sernatinger E, West S, Kuntzman R. The effect of altering liver microsomal co-binding hemoprotein composition on pentobarbital-induced anesthesia. Chemico-Biological Interactions. 5: 183-9. PMID 5047751 DOI: 10.1016/0009-2797(72)90053-1 |
0.524 |
|
| 1972 |
Lu AY, Levin W. Partial purification of cytochromes P-450 and P-448 from rat liver microsomes. Biochemical and Biophysical Research Communications. 46: 1334-9. PMID 5012170 DOI: 10.1016/S0006-291X(72)80121-9 |
0.576 |
|
| 1971 |
Lu AY, Kuntzman R, West S, Conney AH. Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. I. Determination of substrate specificity by the cytochrome P-450 and P-448 fractions. Biochemical and Biophysical Research Communications. 42: 1200-6. PMID 5550806 DOI: 10.1016/0006-291X(71)90033-7 |
0.572 |
|
| 1970 |
Strobel HW, Lu AY, Heidema J, Coon MJ. Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. The Journal of Biological Chemistry. 245: 4851-4. PMID 4393962 |
0.546 |
|
| 1970 |
Lu AY, Strobel HW, Coon MJ. Properties of a solubilized form of the cytochrome P-450-containing mixed-function oxidase of liver microsomes. Molecular Pharmacology. 6: 213-20. PMID 4315336 |
0.63 |
|
| 1969 |
Lu AY, Strobel HW, Coon MJ. Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation. Biochemical and Biophysical Research Communications. 36: 545-51. PMID 4390187 DOI: 10.1016/0006-291X(69)90339-8 |
0.658 |
|
| 1969 |
Lu AY, Junk KW, Coon MJ. Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components. The Journal of Biological Chemistry. 244: 3714-21. PMID 4389465 |
0.634 |
|
| 1968 |
Lu AY, Coon MJ. Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes. The Journal of Biological Chemistry. 243: 1331-2. PMID 4385007 |
0.613 |
|
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