| Year |
Citation |
Score |
| 2022 |
Nouri K, Pietrancosta N, Le Corre L, Dansette PM, Mansuy D, Boucher JL. Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B. International Journal of Molecular Sciences. 23. PMID 36498943 DOI: 10.3390/ijms232314615 |
0.574 |
|
| 2022 |
Boyd DR, Sharma ND, Stevenson PJ, Hoering P, Allen CCR, Dansette PM. Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, -Dihydroxylation and Epoxidation. International Journal of Molecular Sciences. 23. PMID 35055091 DOI: 10.3390/ijms23020909 |
0.701 |
|
| 2020 |
Dubois L, Pietrancosta N, Cabaye A, Fanget I, Debacker C, Gilormini PA, Dansette PM, Dairou J, Biot C, Froissart R, Goupil-Lamy A, Bertrand HO, Acher FC, McCort-Tranchepain I, Gasnier B, et al. Amino acids bearing aromatic or heteroaromatic substituents as a new class of ligands for the lysosomal sialic acid transporter sialin (SLC17A5). Journal of Medicinal Chemistry. PMID 32608236 DOI: 10.1021/Acs.Jmedchem.9B02119 |
0.326 |
|
| 2020 |
Dali MM, Dansette PM, Mansuy D, Boucher JL. Comparison of various aryl-dithiolethiones and aryl-dithiolones as hydrogen sulfide, H2S, donors in the presence of rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32234734 DOI: 10.1124/Dmd.119.090274 |
0.646 |
|
| 2019 |
Dulac M, Nagarathinan C, Dansette PM, Mansuy D, Boucher JL. Mechanism of H2S formation from the metabolism of anetholedithiolethione and anetholedithiolone by rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31213461 DOI: 10.1124/Dmd.119.087205 |
0.625 |
|
| 2018 |
Dulac M, Sassi A, Nagarathinan C, Christen MO, Dansette PM, Mansuy D, Boucher JL. Metabolism of anethole dithiolethione by rat and human liver microsomes: formation of various products deriving from its O-demethylation and S-oxidation. Involvement of cytochromes P450 and flavin monooxygenases in these pathways. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30018103 DOI: 10.1124/Dmd.118.082545 |
0.695 |
|
| 2018 |
Lafite P, André F, Graves JP, Zeldin DC, Dansette PM, Mansuy D. Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2. International Journal of Molecular Sciences. 19. PMID 30012976 DOI: 10.3390/Ijms19072066 |
0.619 |
|
| 2018 |
Wang Y, Dansette PM, Pigeon P, Top S, McGlinchey MJ, Mansuy D, Jaouen G. A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties. Chemical Science. 9: 70-78. PMID 29629075 DOI: 10.1039/C7Sc04213B |
0.617 |
|
| 2017 |
Sodhi JK, Delarosa EM, Halladay JS, Driscoll JP, Mulder T, Dansette PM, Khojasteh SC. Inhibitory Effects of Trapping Agents of Sulfur Drug Reactive Intermediates against Major Human Cytochrome P450 Isoforms. International Journal of Molecular Sciences. 18. PMID 28726718 DOI: 10.3390/Ijms18071553 |
0.368 |
|
| 2016 |
Wang Y, Richard MA, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G. Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation. Angewandte Chemie (International Ed. in English). PMID 27276169 DOI: 10.1002/Anie.201603931 |
0.655 |
|
| 2016 |
Wang Y, Richard M, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G. Inside Back Cover: Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation (Angew. Chem. Int. Ed. 35/2016) Angewandte Chemie International Edition. 55: 10523-10523. DOI: 10.1002/Anie.201605536 |
0.631 |
|
| 2016 |
Wang Y, Richard M, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G. Innenrücktitelbild: Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation (Angew. Chem. 35/2016) Angewandte Chemie. 128: 10679-10679. DOI: 10.1002/Ange.201605536 |
0.632 |
|
| 2015 |
Dansette PM, Levent D, Hessani A, Mansuy D. Bioactivation of clopidogrel and prasugrel: factors determining the stereochemistry of the thiol metabolite double bond. Chemical Research in Toxicology. 28: 1338-45. PMID 25970225 DOI: 10.1021/Acs.Chemrestox.5B00133 |
0.646 |
|
| 2015 |
Richard MA, Hamels D, Pigeon P, Top S, Dansette PM, Lee HZ, Vessières A, Mansuy D, Jaouen G. Oxidative metabolism of ferrocene analogues of tamoxifen: characterization and antiproliferative activities of the metabolites. Chemmedchem. 10: 981-90. PMID 25882581 DOI: 10.1002/Cmdc.201500075 |
0.666 |
|
| 2015 |
Dansette PM, Levent D, Hessani A, Mansuy D. Bioactivation of Clopidogrel and Prasugrel: Factors Determining the Stereochemistry of the Thiol Metabolite Double Bond Chemical Research in Toxicology. 28: 1338-1345. DOI: 10.1021/acs.chemrestox.5b00133 |
0.524 |
|
| 2015 |
Richard M, Hamels D, Pigeon P, Top S, Dansette PM, Lee HZS, Vessières A, Mansuy D, Jaouen G. Cover Picture: Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites (ChemMedChem 6/2015) Chemmedchem. 10: 933-933. DOI: 10.1002/Cmdc.201590015 |
0.646 |
|
| 2013 |
Dansette PM, Levent D, Hessani A, Bertho G, Mansuy D. Thiolactone sulfoxides as new reactive metabolites acting as bis-electrophiles: Implication in clopidogrel and prasugrel bioactivation Chemical Research in Toxicology. 26: 794-802. PMID 23527615 DOI: 10.1021/Tx400083B |
0.691 |
|
| 2012 |
Dansette PM, Rosi J, Debernardi J, Bertho G, Mansuy D. Metabolic activation of prasugrel: Nature of the two competitive pathways resulting in the opening of its thiophene ring Chemical Research in Toxicology. 25: 1058-1065. PMID 22482514 DOI: 10.1021/Tx3000279 |
0.682 |
|
| 2012 |
Dansette PM, Rosi J, Bertho G, Mansuy D. Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer Chemical Research in Toxicology. 25: 348-356. PMID 22103858 DOI: 10.1021/Tx2004085 |
0.665 |
|
| 2011 |
Dansette PM, Rosi J, Bertho G, Mansuy D. Paraoxonase-1 and clopidogrel efficacy. Nature Medicine. 17: 1040-1041; author re. PMID 21900914 DOI: 10.1038/Nm.2436 |
0.515 |
|
| 2011 |
Mansuy D, Dansette PM. Sulfenic acids as reactive intermediates in xenobiotic metabolism Archives of Biochemistry and Biophysics. 507: 174-185. PMID 20869346 DOI: 10.1016/J.Abb.2010.09.015 |
0.634 |
|
| 2011 |
Dansette PM, Rosi J, Bertho G, Mansuy D. To the editor Nature Medicine. 17: 1040-1041. DOI: 10.1038/nm.2436 |
0.469 |
|
| 2010 |
Dansette PM, Thébault S, Bertho G, Mansuy D. Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel Chemical Research in Toxicology. 23: 1268-1274. PMID 20557086 DOI: 10.1021/Tx1001332 |
0.698 |
|
| 2010 |
MANSUY D, VALADON P, ERDELMEIER I, LOPEZ-GARCIA P, AMAR C, GIRAULT J, DANSETTE PM. ChemInform Abstract: Thiophene S-Oxides as New Reactive Metabolites: Formation by Cytochrome P450 Dependent Oxidation and Reaction with Nucleophiles. Cheminform. 23: no-no. DOI: 10.1002/chin.199201075 |
0.626 |
|
| 2009 |
Hamels D, Dansette PM, Hillard EA, Top S, Vessières A, Herson P, Jaouen G, Mansuy D. Ferrocenyl quinone methides as strong antiproliferative agents: Formation by metabolic and chemical oxidation of ferrocenyl phenols Angewandte Chemie - International Edition. 48: 9124-9126. PMID 19876986 DOI: 10.1002/Anie.200903768 |
0.639 |
|
| 2009 |
Dansette PM, Libraire J, Bertho G, Mansuy D. Metabolie oxidative cleavage of thioesters: Evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and clopidogrel Chemical Research in Toxicology. 22: 369-373. PMID 19170597 DOI: 10.1021/Tx8004828 |
0.651 |
|
| 2009 |
Sun H, Moore C, Dansette PM, Kumar S, Halpert JR, Yost GS. Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 672-84. PMID 19074530 DOI: 10.1124/Dmd.108.022707 |
0.397 |
|
| 2008 |
Schoch GA, Yano JK, Sansen S, Dansette PM, Stout CD, Johnson EF. Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. The Journal of Biological Chemistry. 283: 17227-37. PMID 18413310 DOI: 10.1074/Jbc.M802180200 |
0.482 |
|
| 2008 |
Nguyen TA, Tychopoulos M, Bichat F, Zimmermann C, Flinois JP, Diry M, Ahlberg E, Delaforge M, Corcos L, Beaune P, Dansette P, André F, de Waziers I. Improvement of cyclophosphamide activation by CYP2B6 mutants: from in silico to ex vivo. Molecular Pharmacology. 73: 1122-33. PMID 18212249 DOI: 10.1124/Mol.107.042861 |
0.336 |
|
| 2007 |
Lafite P, André F, Zeldin DC, Dansette PM, Mansuy D. Unusual regioselectivity and active site topology of human cytochrome P450 2J2 Biochemistry. 46: 10238-10247. PMID 17705402 DOI: 10.1021/Bi700876A |
0.658 |
|
| 2007 |
Lafite P, Dijols S, Zeldin DC, Dansette PM, Mansuy D. Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2 Archives of Biochemistry and Biophysics. 464: 155-168. PMID 17470359 DOI: 10.1016/J.Abb.2007.03.028 |
0.635 |
|
| 2007 |
Bochot C, Bartoli JF, Frapart Y, Dansette PM, Mansuy D, Battioni P. Synthesis and spectroscopic, electrochemical, and catalytic properties of a new manganese porphyrin bearing four positive charges close to the metal Journal of Molecular Catalysis a: Chemical. 263: 200-205. DOI: 10.1016/J.Molcata.2006.08.032 |
0.581 |
|
| 2006 |
Lafite P, Dijols S, Buisson D, Macherey AC, Zeldin DC, Dansette PM, Mansuy D. Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2 Bioorganic and Medicinal Chemistry Letters. 16: 2777-2780. PMID 16495056 DOI: 10.1016/J.Bmcl.2006.02.004 |
0.614 |
|
| 2005 |
López-García MP, Dansette PM, Coloma J. Kinetics of tienilic acid bioactivation and functional generation of drug-protein adducts in intact rat hepatocytes. Biochemical Pharmacology. 70: 1870-82. PMID 16257391 DOI: 10.1016/J.Bcp.2005.09.026 |
0.349 |
|
| 2005 |
Fontana E, Dansette PM, Poli SM. Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current Drug Metabolism. 6: 413-54. PMID 16248836 DOI: 10.2174/138920005774330639 |
0.354 |
|
| 2005 |
Dansette PM, Bertho G, Mansuy D. First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives Biochemical and Biophysical Research Communications. 338: 450-455. PMID 16137656 DOI: 10.1016/J.Bbrc.2005.08.091 |
0.661 |
|
| 2004 |
Melet A, Marques-Soares C, Schoch GA, Macherey AC, Jaouen M, Dansette PM, Sari MA, Johnson EF, Mansuy D. Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants Biochemistry. 43: 15379-15392. PMID 15581350 DOI: 10.1021/Bi0489309 |
0.707 |
|
| 2003 |
Schoch GA, Attias R, Belghazi M, Dansette PM, Werck-Reichhart D. Engineering of a water-soluble plant cytochrome P450, CYP73A1, and NMR-based orientation of natural and alternate substrates in the active site. Plant Physiology. 133: 1198-208. PMID 14576280 DOI: 10.1104/Pp.103.020305 |
0.396 |
|
| 2003 |
Wester MR, Johnson EF, Marques-Soares C, Dijols S, Dansette PM, Mansuy D, Stout CD. Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 Å resolution: Evidence for an induced fit model of substrate binding Biochemistry. 42: 9335-9345. PMID 12899620 DOI: 10.1021/Bi034556L |
0.71 |
|
| 2003 |
Wester MR, Johnson EF, Marques-Soares C, Dansette PM, Mansuy D, Stout CD. Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 Å resolution: Evidence for multiple substrate binding modes Biochemistry. 42: 6370-6379. PMID 12767218 DOI: 10.1021/Bi0273922 |
0.696 |
|
| 2003 |
Marques-Soares C, Dijols S, Macherey AC, Wester MR, Johnson EF, Dansette PM, Mansuy D. Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: Identification of a new high affinity substrate common to those enzymes Biochemistry. 42: 6363-6369. PMID 12767217 DOI: 10.1021/Bi027391+ |
0.73 |
|
| 2003 |
Melet A, Assrir N, Jean P, Lopez-Garcia MP, Marques-Soares C, Jaouen M, Dansette PM, Sari MA, Mansuy D. Substrate selectivity of human cytochrome P450 2C9: Importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid Archives of Biochemistry and Biophysics. 409: 80-91. PMID 12464247 DOI: 10.1016/S0003-9861(02)00548-9 |
0.778 |
|
| 2002 |
Treiber A, Dansette PM, Mansuy D. Mechanism of the aromatic hydroxylation of thiophene by acid-catalyzed peracid oxidation. The Journal of Organic Chemistry. 67: 7261-6. PMID 12375952 DOI: 10.1021/Jo0202177 |
0.768 |
|
| 2001 |
Ha-Duong NT, Dijols S, Macherey AC, Dansette PM, Mansuy D. Inhibition by ticlopidine and its derivatives of human liver cytochrome P450. Mechanism-based inactivation of CYP 2C19 by ticlopidine Advances in Experimental Medicine and Biology. 500: 145-148. PMID 11764927 DOI: 10.1007/978-1-4615-0667-6_18 |
0.658 |
|
| 2001 |
Belghazi M, Jean P, Poli S, Schmitter JM, Mansuy D, Dansette PM. Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation Advances in Experimental Medicine and Biology. 500: 139-144. PMID 11764926 |
0.539 |
|
| 2001 |
Ha-Duong NT, Dijols S, Marques-Soares C, Minoletti C, Dansette PM, Mansuy D. Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily Journal of Medicinal Chemistry. 44: 3622-3631. PMID 11606127 DOI: 10.1021/Jm010861Y |
0.627 |
|
| 2001 |
Ha-Duong NT, Marques-Soares C, Dijols S, Sari MA, Dansette PM, Mansuy D. Interaction of new sulfaphenazole derivatives with human liver cytochrome P450 2Cs: Structural determinants required for selective recognition by CYP 2C9 and for inhibition of human CYP 2Cs Archives of Biochemistry and Biophysics. 394: 189-200. PMID 11594733 DOI: 10.1006/Abbi.2001.2511 |
0.634 |
|
| 2001 |
Ha-Duong NT, Dijols S, Macherey AC, Goldstein JA, Dansette PM, Mansuy D. Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19 Biochemistry. 40: 12112-12122. PMID 11580286 DOI: 10.1021/Bi010254C |
0.69 |
|
| 2001 |
Lakehal F, Dansette PM, Becquemont L, Lasnier E, Delelo R, Balladur P, Poupon R, Beaune PH, Housset C. Indirect cytotoxicity of flucloxacillin toward human biliary epithelium via metabolite formation in hepatocytes. Chemical Research in Toxicology. 14: 694-701. PMID 11409940 DOI: 10.1021/Tx0002435 |
0.358 |
|
| 1999 |
Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong NT, Battioni P, Dansette PM, Mansuy D. Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs. Biochemistry. 38: 14264-70. PMID 10572000 DOI: 10.1021/Bi991195U |
0.681 |
|
| 1999 |
Minoletti C, Dijols S, Dansette PM, Mansuy D. Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18. Biochemistry. 38: 7828-36. PMID 10387023 DOI: 10.1021/Bi9903289 |
0.661 |
|
| 1999 |
Bonierbale E, Valadon P, Pons C, Desfosses B, Dansette PM, Mansuy D. Opposite behaviors of reactive metabolites of tienilic acid and its isomer toward liver proteins: use of specific anti-tienilic acid-protein adduct antibodies and the possible relationship with different hepatotoxic effects of the two compounds. Chemical Research in Toxicology. 12: 286-96. PMID 10077492 DOI: 10.1021/Tx980136Z |
0.65 |
|
| 1998 |
Dansette PM, Bonierbale E, Minoletti C, Beaune PH, Pessayre D, Mansuy D. Drug-induced immunotoxicity. European Journal of Drug Metabolism and Pharmacokinetics. 23: 443-51. PMID 10323325 DOI: 10.1007/Bf03189993 |
0.589 |
|
| 1998 |
Minoletti C, Mancy A, Ha-Duong T, Dijols S, Dansette P, Mansuy D. Design of CYP 2C18 and 2C19 substrates based on hydroxylation of 2-aroyl-thiophenes Toxicology Letters. 95: 98. DOI: 10.1016/S0378-4274(98)80390-1 |
0.616 |
|
| 1998 |
Ho MT, Treiber A, Dansette PM. Oxidation of 2-(4-chlorobenzoyl)-thiophene into 1-oxide Diels-Alder dimers, sesquioxide and a sulfone-water adduct Tetrahedron Letters. 39: 5049-5052. DOI: 10.1016/S0040-4039(98)01004-1 |
0.693 |
|
| 1998 |
Pouzet P, Erdelmeier I, Dansette PM, Mansuy D. Synthesis of (4-chlorophenyl)-(1-oxo-1λ4-benzo[b]thien-2-yl)methanone and study of its reactivity towards sulfur- and oxygen-containing nucleophiles Tetrahedron. 54: 14811-14824. DOI: 10.1016/S0040-4020(98)00929-6 |
0.616 |
|
| 1997 |
Poli-Scaife S, Attias R, Dansette PM, Mansuy D. The substrate binding site of human liver cytochrome P450 2C9: An NMR study Biochemistry. 36: 12672-12682. PMID 9335524 DOI: 10.1021/Bi970527X |
0.749 |
|
| 1997 |
Treiber A, Dansette PM, El Amri H, Girault JP, Ginderow D, Mornon JP, Mansuy D. Chemical and biological oxidation of thiophene: Preparation and complete characterization of thiophene S-oxide dimers and evidence for thiophene S-oxide as an intermediate in thiophene metabolism in vivo and in vitro Journal of the American Chemical Society. 119: 1565-1571. DOI: 10.1021/Ja962466G |
0.776 |
|
| 1997 |
Pouzet P, Erdelmeier I, Ginderow D, Dansette PM, Mansuy D, Mornon J. Thiophene 1-oxides.V. Comparison of the crystal structures and thiophene ring aromaticity of 2,5-diphenylthiophene, its sulfoxide and sulfone Journal of Heterocyclic Chemistry. 34: 1567-1574. DOI: 10.1002/Jhet.5570340530 |
0.637 |
|
| 1997 |
Mansuy D, Jean P, Pothicr J, Dansette P, Viari A. Automated multiple analysis of protein structures: application to homology modeling of cytochromes P450 Faseb Journal. 11: A778. DOI: 10.1002/(SICI)1097-0134(199707)28:3<388::AID-PROT9>3.0.CO;2-8 |
0.533 |
|
| 1996 |
Beaune PH, Lecoeur S, Bourdi M, Gauffre A, Belloc C, Dansette P, Mansuy D. Anti-cytochrome p450 autoantibodies in drug-induced disease European Journal of Haematology, Supplement. 57: 89-92. PMID 8987248 DOI: 10.1111/J.1600-0609.1996.Tb01652.X |
0.627 |
|
| 1996 |
Valadon P, Dansette PM, Girault JP, Amar C, Mansuy D. Thiophene sulfoxides as reactive metabolites: Formation upon microsomal oxidation of a 3-aroylthiophene and fate in the presence of nucleophiles in vitro and in vivo Chemical Research in Toxicology. 9: 1403-1413. PMID 8951246 DOI: 10.1021/Tx9601622 |
0.674 |
|
| 1996 |
Jean P, Lopez-Garcia P, Dansette P, Mansuy D, Goldstein JL. Oxidation of tienilic acid by human yeast-expressed cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this drug is a mechanism-based inhibitor specific for cytochrome P-450 2C9. European Journal of Biochemistry / Febs. 241: 797-804. PMID 8944768 DOI: 10.1111/J.1432-1033.1996.00797.X |
0.677 |
|
| 1996 |
Robin MA, Maratrat M, Le Roy M, Le Breton FP, Bonierbale E, Dansette P, Ballet F, Mansuy D, Pessayre D. Antigenic targets in tienilic acid hepatitis: Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera Journal of Clinical Investigation. 98: 1471-1480. PMID 8823314 DOI: 10.1172/Jci118936 |
0.63 |
|
| 1996 |
Pons C, Dansette PM, Gregeois J, Homberg JC, Billett EE, Mansuy D. Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B Biochemical and Biophysical Research Communications. 218: 118-124. PMID 8573115 DOI: 10.1006/Bbrc.1996.0021 |
0.591 |
|
| 1995 |
Mancy A, Broto P, Dijols S, Dansette PM, Mansuy D. The substrate binding site of human liver cytochrome P450 2C9: An approach using designed tienilic acid derivatives and molecular modeling Biochemistry. 34: 10365-10375. PMID 7654690 DOI: 10.1021/Bi00033A007 |
0.652 |
|
| 1995 |
Pouzet P, Erdelmeier I, Ginderow D, Mornon JP, Dansette P, Mansuy D. Thiophene S-oxides: Convenient preparation, first complete structural characterization and unexpected dimerization of one of them, 2,5-diphenylthiophene-1-oxide Journal of the Chemical Society, Chemical Communications. 473-474. DOI: 10.1039/C39950000473 |
0.638 |
|
| 1994 |
López-Garcia MP, Dansette PM, Mansuy D. Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: Inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid Biochemistry. 33: 166-175. PMID 8286335 DOI: 10.1021/Bi00167A022 |
0.691 |
|
| 1994 |
Lecoeur S, Bonierbale E, Challine D, Gautier JC, Valadon P, Dansette PM, Catinot R, Ballet F, Mansuy D, Beaune PH. Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: Comparison with two directly hepatotoxic drugs Chemical Research in Toxicology. 7: 434-442. PMID 8075377 DOI: 10.1021/Tx00039A023 |
0.668 |
|
| 1994 |
Beaune P, Pessayre D, Dansette P, Mansuy D, Manns M. Autoantibodies against cytochromes P450: role in human diseases Advances in Pharmacology (San Diego, Calif.). 30: 199-245. PMID 7833293 DOI: 10.1016/S1054-3589(08)60175-1 |
0.604 |
|
| 1993 |
Lopez Garcia MP, Dansette PM, Valadon P, Amar C, Beaune PH, Guengerich FP, Mansuy D. Human-liver cytochromes P-450 expressed in yeast as tools for reactive-metabolite formation studies. Oxidative activation of tienilic acid by cytochromes P-450 2C9 and 2C10. European Journal of Biochemistry. 213: 223-32. PMID 8477697 DOI: 10.1111/J.1432-1033.1993.Tb17752.X |
0.69 |
|
| 1993 |
Ginderow D, Mornon JP, Erdelmeier I, Dansette P, Mansuy D. Structure du 2,5-diphényl-3-furyl 2,5-diphényl-3-thiényl sulfoxyde Acta Crystallographica Section C Crystal Structure Communications. 49: 2009-2012. DOI: 10.1107/S0108270193005487 |
0.488 |
|
| 1992 |
Dansette PM, Thang DC, el Amri H, Mansuy D. Evidence for thiophene-S-oxide as a primary reactive metabolite of thiophene in vivo: formation of a dihydrothiophene sulfoxide mercapturic acid. Biochemical and Biophysical Research Communications. 186: 1624-30. PMID 1510686 DOI: 10.1016/S0006-291X(05)81594-3 |
0.662 |
|
| 1992 |
Martinat C, Amar C, Dansette PM, Leclaire J, Lopez-Garcia P, Cao TD, N'Guyen HN, Mansuy D. In vitro metabolism of isaxonine phosphate: formation of two metabolites, 5-hydroxyisaxonine and 2-aminopyrimidine, and covalent binding to microsomal proteins. European Journal of Pharmacology. 228: 63-71. PMID 1397069 DOI: 10.1016/0926-6917(92)90013-3 |
0.656 |
|
| 1992 |
Ginderow D, Mornon JP, Erdelmeier I, Dansette P, Mansuy D. Structure du 2,3-dihydro-3-(2-hydroxyéthylthio)benzo[b]thiophène 1-oxyde, C10H12O2S2 Acta Crystallographica Section C Crystal Structure Communications. 48: 1808-1810. DOI: 10.1107/S0108270192002002 |
0.5 |
|
| 1991 |
Dansette PM, Amar C, Valadon P, Pons C, Beaune PH, Mansuy D. Hydroxylation and formation of electrophilic metabolites of tienilic acid and its isomer by human liver microsomes. Catalysis by a cytochrome P450 IIC different from that responsible for mephenytoin hydroxylation. Biochemical Pharmacology. 41: 553-60. PMID 1997003 DOI: 10.1016/0006-2952(91)90627-H |
0.671 |
|
| 1991 |
Ruimy-Ifrah P, Jore D, Christen M, Dansette P, Mansuy D, Ferradini C. Étude radiolytique de réactions radicalaires du sulfarlem Journal De Chimie Physique. 88: 907-912. DOI: 10.1051/Jcp/1991880907 |
0.528 |
|
| 1991 |
Mansuy D, Valadon P, Erdelmeier I, Lopez-Garcia P, Amar C, Girault JP, Dansette PM. Thiophene S-oxides as new reactive metabolites: formation by cytochrome P-450 dependent oxidation and reaction with nucleophiles Journal of the American Chemical Society. 113: 7825-7826. DOI: 10.1021/Ja00020A089 |
0.659 |
|
| 1990 |
Neau E, Dansette PM, Andronik V, Mansuy D. Hydroxylation of the thiophene ring by hepatic monooxygenases. Evidence for 5-hydroxylation of 2-aroylthiophenes as a general metabolic pathway using a simple UV-visible assay. Biochemical Pharmacology. 39: 1101-7. PMID 2322296 DOI: 10.1016/0006-2952(90)90290-2 |
0.641 |
|
| 1990 |
Dansette PM, Amar C, Smith C, Pons C, Mansuy D. Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes. Biochemical Pharmacology. 39: 911-8. PMID 2310416 DOI: 10.1016/0006-2952(90)90207-2 |
0.682 |
|
| 1990 |
Dansette PM, Sassi A, Deschamps C, Mansuy D. Sulfur containing compounds as antioxidants Advances in Experimental Medicine and Biology. 264: 209-215. PMID 2244498 DOI: 10.1007/978-1-4684-5730-8_34 |
0.587 |
|
| 1990 |
Azerad R, Boucher J, Dansette P, Delaforge M. High-performance liquid chromatographic separation of 11-hydroxylauric acid enantiomers Journal of Chromatography A. 498: 293-302. DOI: 10.1016/S0021-9673(01)84259-X |
0.334 |
|
| 1989 |
Larrey D, Berson A, Habersetzer F, Tinel M, Castot A, Babany G, Lettéron P, Freneaux E, Loeper J, Dansette P. Genetic predisposition to drug hepatotoxicity: role in hepatitis caused by amineptine, a tricyclic antidepressant. Hepatology (Baltimore, Md.). 10: 168-73. PMID 2744728 DOI: 10.1002/Hep.1840100208 |
0.373 |
|
| 1987 |
Beaune P, Dansette PM, Mansuy D, Kiffel L, Finck M, Amar C, Leroux JP, Homberg JC. Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug. Proceedings of the National Academy of Sciences of the United States of America. 84: 551-5. PMID 3540968 DOI: 10.1073/Pnas.84.2.551 |
0.609 |
|
| 1986 |
Mansuy D, Sassi A, Dansette PM, Plat M. A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione Biochemical and Biophysical Research Communications. 135: 1015-1021. PMID 3964266 DOI: 10.1016/0006-291X(86)91029-6 |
0.592 |
|
| 1986 |
Dansette PM, Delaforge M, Sartori E, Beaune P, Jaouen M, Mansuy D. Drug interactions with macrolide antibiotics: specificity of pseudo-suicide inhibition and induction of cytochrome P-450. Advances in Experimental Medicine and Biology. 197: 155-62. PMID 3490132 DOI: 10.1007/978-1-4684-5134-4_12 |
0.638 |
|
| 1984 |
Mansuy D, Dansette PM, Foures C, Jaouen M, Moinet G, Bayer N. Metabolic hydroxylation of the thiophene ring: isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and rat. Biochemical Pharmacology. 33: 1429-35. PMID 6732860 DOI: 10.1016/0006-2952(84)90409-X |
0.62 |
|
| 1984 |
Rouet P, Dansette P, Frayssinet C. Ontogeny of benzo(a)pyrene hydroxylase, epoxide hydrolase and glutathione-S transferase in the brain, lung and liver of C57Bl/6 mice. Developmental Pharmacology and Therapeutics. 7: 245-58. PMID 6468226 DOI: 10.1159/000457171 |
0.303 |
|
| 1984 |
Tauc M, Hermann M, Dansette PM, Vandecasteele JP. Enzymatic characterization of the polynuclear aromatic hydrocarbons activating rat-liver preparations used in the mutagenicity test of Ames. Mutation Research. 125: 123-33. PMID 6366528 DOI: 10.1016/0027-5107(84)90064-2 |
0.349 |
|
| 1984 |
Mansuy D, Leclaire J, Fontecave M, Dansette P. Regioselectivity of olefin oxidation by iodosobenzene catalyzed by metalloporphyrins : control by the catalyst Tetrahedron. 40: 2847-2857. DOI: 10.1016/S0040-4020(01)91293-1 |
0.623 |
|
| 1983 |
Rouer E, Mahu JL, Columelli S, Dansette P, Leroux JP. Induction of drug metabolizing enzymes in the liver of diabetic mice. Biochimie. 64: 961-7. PMID 6295511 DOI: 10.1016/S0300-9084(82)80360-X |
0.309 |
|
| 1982 |
Lafarge-Frayssinet C, Alexandrov K, Rimbaut C, Dansette PM, Mousset S, Frayssinet C. Presence of benzo[a]pyrene metabolizing activities in isolated rat liver nucleoli. Carcinogenesis. 2: 1189-93. PMID 6274539 DOI: 10.1093/Carcin/2.11.1189 |
0.413 |
|
| 1982 |
Rouet P, Alexandrov K, Markovits P, Frayssinet C, Dansette PM. Metabolism of benzo[a]pyrene by brain microsomes of fetal and adult rats and mice. Induction by 5,6 benzoflavone, comparison with liver and lung microsomal activities. Carcinogenesis. 2: 919-26. PMID 6271416 DOI: 10.1093/Carcin/2.9.919 |
0.359 |
|
| 1981 |
Mansuy D, Dansette PM, Pecquet F, Chottard JC. Iron-porphyrin catalysis of the oxidative dealkylation of para-nitro-anisole and 7-ethoxycoumarin by cumylhydroperoxide: a possible model for the corresponding cytochrome P 450-dependent reactions. Biochemical and Biophysical Research Communications. 96: 433-9. PMID 7437045 DOI: 10.1016/0006-291X(80)91233-4 |
0.607 |
|
| 1980 |
Alexandrov K, Dansette PM, Frayssinet C. Effect of purified epoxide hydrolase on metabolic activation and binding of benzo(a)pyrene to exogenous DNA. Shift of the activation pathway. Biochemical and Biophysical Research Communications. 93: 611-6. PMID 7190013 DOI: 10.1016/0006-291X(80)91122-5 |
0.367 |
|
| 1980 |
Cresteil T, Mahu JL, Dansette PM, Leroux JP. In vivo administration of hydroxylated phenobarbital metabolites: effect on rat hepatic cytochromes P-450, epoxide hydrolase and UDP-glucuronosyltransferase. Biochemical Pharmacology. 29: 1127-33. PMID 6770872 DOI: 10.1016/0006-2952(80)90407-4 |
0.382 |
|
| 1980 |
Beaune P, Kremers P, Dansette PM, Flinois JP, Leroux JP. Monooxygenase Activities Of Partially Purified Cytochromes P-450 From Human Liver Microsomes Microsomes, Drug Oxidations and Chemical Carcinogenesis. 107-110. DOI: 10.1016/B978-0-12-187701-9.50017-6 |
0.36 |
|
| 1979 |
Dansette PM, DuBois GC, Jerina DM. Continous fluorometric assay of epoxide hydrase activity. Analytical Biochemistry. 97: 340-5. PMID 525797 DOI: 10.1016/0003-2697(79)90083-6 |
0.562 |
|
| 1979 |
James MO, Bowen ER, Dansette PM, Bend JR. Epoxide hydrase and glutathione S-transferase activities with selected alkene and adrene oxides in several marine species. Chemico-Biological Interactions. 25: 321-44. PMID 466737 DOI: 10.1016/0009-2797(79)90055-3 |
0.383 |
|
| 1979 |
Beaune P, Dansette P, Flinois JP, Columelli S, Mansuy D, Leroux JP. Partial purification of human liver cytochrome P 450. Biochemical and Biophysical Research Communications. 88: 826-32. PMID 465082 DOI: 10.1016/0006-291X(79)91482-7 |
0.629 |
|
| 1978 |
Dansette PM, Makedonska VB, Jerina DM. Mechanism of catalysis for the hydration of substituted styrene oxides by hepatic epoxide hydrase. Archives of Biochemistry and Biophysics. 187: 290-8. PMID 666312 DOI: 10.1016/0003-9861(78)90037-1 |
0.551 |
|
| 1977 |
Bresnick E, Mukhtar H, Stoming TA, Dansette PM, Jerina DM. Effect of phenobarbital and 3-methylcholanthrene administration on epoxide hydrase levels in liver microsomes. Biochemical Pharmacology. 26: 891-2. PMID 861055 DOI: 10.1016/0006-2952(77)90406-3 |
0.399 |
|
| 1977 |
Kapitulnik J, Levin W, Morecki R, Dansette PM, Jerina DM, Conney AH. Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes. Clinical Pharmacology and Therapeutics. 21: 158-65. PMID 65238 DOI: 10.1002/Cpt1977212158 |
0.59 |
|
| 1977 |
Whalen DL, Ross AM, Dansette PM, Jerina DM. Specific effects of chloride ion in the hydrolysis of a K-region arene oxide Journal of the American Chemical Society. 99: 5672-5676. DOI: 10.1021/Ja00459A024 |
0.499 |
|
| 1977 |
WHALEN DL, ROSS AM, DANSETTE PM, JERINA DM. ChemInform Abstract: SPECIFIC EFFECTS OF CHLORIDE ION IN THE HYDROLYSIS OF A K-REGION ARENE OXIDE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197747093 |
0.434 |
|
| 1976 |
Levin W, Wood AW, Yagi H, Dansette PM, Jerina DM, Conney AH. Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin. Proceedings of the National Academy of Sciences of the United States of America. 73: 243-7. PMID 1061121 DOI: 10.1073/Pnas.73.1.243 |
0.542 |
|
| 1976 |
Yagi H, Holder GM, Dansette PM, Hernandez O, Yeh HJC, LeMahieu RA, Jerina DM. Synthesis and spectral properties of the isomeric hydroxybenzo[a]pyrenes The Journal of Organic Chemistry. 41: 977-985. DOI: 10.1021/Jo00868A017 |
0.449 |
|
| 1976 |
Bruice PY, Bruice TC, Dansette PM, Selander HG, Yagi H, Jerina DM. Comparison of the mechanisms of solvolysis and rearrangement of K-region vs. non-K-region arene oxides of phenanthrene. Comparative solvolytic rate constants of K-region and non-K-region arene oxides Journal of the American Chemical Society. 98: 2965-2973. DOI: 10.1021/Ja00426A048 |
0.485 |
|
| 1976 |
Silverton J, Dansette P, Jerina D. Oxidation of 4,5-dihydrobenzo[a]pyrene with osmium tetroxide. Stereochemistry of a substituted K-region diol. Tetrahedron Letters. 17: 1557-1560. DOI: 10.1016/S0040-4039(01)91615-6 |
0.526 |
|
| 1976 |
Dansette P, Ziffer H, Jerina D. Optically active 4-substituted cis-1,2-diphenylethylene oxides and related 1,2-diphenylethane diols Tetrahedron. 32: 2071-2074. DOI: 10.1016/0040-4020(76)85110-1 |
0.508 |
|
| 1976 |
Yagi H, Dansette P, Jerina DM. Specifically tritiated arene oxides Journal of Labelled Compounds and Radiopharmaceuticals. 12: 127-132. DOI: 10.1002/Jlcr.2580120115 |
0.544 |
|
| 1976 |
DANSETTE PM, ZIFFER H, JERINA DM. ChemInform Abstract: OPTICALLY ACTIVE 4-SUBSTITUTED CIS-1,2-DIPHENYLETHYLENE OXIDES AND RELATED 1,2-DIPHENYLETHANE DIOLS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197652206 |
0.427 |
|
| 1976 |
BRUICE PY, BRUICE TC, DANSETTE PM, SELANDER HG, YAGI H, JERINA DM. ChemInform Abstract: COMPARISON OF THE MECHANISMS OF SOLVOLYSIS AND REARRANGEMENT OF K-REGION VS. NON-K-REGION ARENE OXIDES OF PHENANTHRENE. COMPARATIVE SOLVOLYTIC RATE CONSTANTS OF K-REGION AND NON-K-REGION ARENE OXIDES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197631079 |
0.486 |
|
| 1976 |
YAGI H, HOLDER GM, DANSETTE PM, HERNANDEZ O, YEH HJC, LEMAHIEU RA, JERINA DM. ChemInform Abstract: SYNTHESIS AND SPECTRAL PROPERTIES OF THE ISOMERIC HYDROXYBENZO(A)PYRENES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197626189 |
0.451 |
|
| 1975 |
Dansette P, Azerad R. The shikimate pathway : II. Stereospecificity of hydrogen transfer catalyzed by NADPH-dehydroshikimate reductase of E. coli. Biochimie. 56: 751-5. PMID 4155957 DOI: 10.1016/S0300-9084(74)80046-5 |
0.703 |
|
| 1975 |
Wood AW, Goode RL, Chang RL, Levin W, Conney AH, Yagi H, Dansette PM, Jerina DM. Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols. Proceedings of the National Academy of Sciences of the United States of America. 72: 3176-80. PMID 1103140 DOI: 10.1073/Pnas.72.8.3176 |
0.538 |
|
| 1975 |
Moriarty R, Dansette P, Jerina D. Pyrene derivatives oxygenated at both K-regions. Synthesis of a bis-arene oxide. Tetrahedron Letters. 16: 2557-2560. DOI: 10.1016/S0040-4039(00)75177-X |
0.525 |
|
| 1975 |
MORIARTY RM, DANSETTE P, JERINA DM. ChemInform Abstract: PYRENE DERIVATIVES OXYGENATED AT BOTH K-REGIONS, SYNTHESIS OF A BIS-ARENE OXIDE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197543252 |
0.462 |
|
| 1974 |
Dansette P, Jerina DM. A facile synthesis of arene oxides at the K regions of polycylic hydrocarbons. Journal of the American Chemical Society. 96: 1224-5. PMID 4816471 DOI: 10.1002/Chin.197417257 |
0.521 |
|
| 1974 |
Dansette P, Azerad R. The shikimate pathway. I. Preparation of 3-3H, 4-3H and 2,4-3H2 D-shikimic acid. Biochimie. 55: 583-9. PMID 4754189 DOI: 10.1016/S0300-9084(73)80420-1 |
0.717 |
|
| 1974 |
Holder G, Yagi H, Dansette P, Jerina DM, Levin W, Lu AY, Conney AH. Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proceedings of the National Academy of Sciences of the United States of America. 71: 4356-4360. PMID 4530987 DOI: 10.1073/Pnas.71.11.4356 |
0.577 |
|
| 1974 |
Dansette PM, Yagi H, Jerina DM, Daly JW, Levin W, Lu AY, Kuntzman R, Conney AH. Assay and partial purification of epoxide hydrase from rat liver microsomes. Archives of Biochemistry and Biophysics. 164: 511-7. PMID 4460878 DOI: 10.1016/0003-9861(74)90061-7 |
0.666 |
|
| 1974 |
DANSETTE P, JERINA DM. ChemInform Abstract: A FACILE SYNTHESIS OF ARENE OXIDES AT THE K REGIONS OF POLYCYCLIC HYDROCARBONS Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/chin.197417257 |
0.46 |
|
| 1970 |
Leduc MM, Dansette PM, Azerad RG. [Incorporation of shikimic acid into the ring of bacterial and plant naphthoquinones]. European Journal of Biochemistry. 15: 428-35. PMID 5455660 DOI: 10.1111/J.1432-1033.1970.Tb01025.X |
0.347 |
|
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