Simon Bullock - Publications

Affiliations: 
University of Cambridge (UK) 

34/51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wong CH, Wingett SW, Qian C, Hunter MR, Taliaferro JM, Ross-Thriepland D, Bullock SL. Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen. The Journal of Cell Biology. 223. PMID 38448164 DOI: 10.1083/jcb.202306048  0.39
2024 Heber S, McClintock MA, Simon B, Mehtab E, Lapouge K, Hennig J, Bullock SL, Ephrussi A. Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport. Nature Structural & Molecular Biology. PMID 38297086 DOI: 10.1038/s41594-024-01212-x  0.452
2023 Madan V, Albacete-Albacete L, Jin L, Scaturro P, Watson JL, Muschalik N, Begum F, Boulanger J, Bauer K, Kiebler MA, Derivery E, Bullock SL. HEATR5B associates with dynein-dynactin and promotes motility of AP1-bound endosomal membranes. The Embo Journal. e114473. PMID 37872872 DOI: 10.15252/embj.2023114473  0.363
2023 Gáspár I, Phea LJ, McClintock MA, Heber S, Bullock SL, Ephrussi A. An RNA-based feed-forward mechanism ensures motor switching in oskar mRNA transport. The Journal of Cell Biology. 222. PMID 37213090 DOI: 10.1083/jcb.202301113  0.407
2023 Wong CH, Wingett SW, Qian C, Taliaferro JM, Ross-Thriepland D, Bullock SL. Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen. Biorxiv : the Preprint Server For Biology. PMID 36909483 DOI: 10.1101/2023.03.01.530592  0.427
2021 Fumagalli L, Young FL, Boeynaems S, De Decker M, Mehta AR, Swijsen A, Fazal R, Guo W, Moisse M, Beckers J, Dedeene L, Selvaraj BT, Vandoorne T, Madan V, van Blitterswijk M, ... ... Bullock SL, et al. -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science Advances. 7. PMID 33837088 DOI: 10.1126/sciadv.abg3013  0.434
2020 Vincent J, Preston M, Mouchet E, Laugier N, Corrigan A, Boulanger J, Brown DG, Clark R, Wigglesworth M, Carter AP, Bullock SL. A High-Throughput Cellular Screening Assay for Small-Molecule Inhibitors and Activators of Cytoplasmic Dynein-1-Based Cargo Transport. Slas Discovery : Advancing Life Sciences R & D. 2472555220920581. PMID 32436764 DOI: 10.1177/2472555220920581  0.309
2020 Elshenawy MM, Kusakci E, Volz S, Baumbach J, Bullock SL, Yildiz A. Lis1 activates dynein motility by modulating its pairing with dynactin. Nature Cell Biology. PMID 32341547 DOI: 10.1038/S41556-020-0501-4  0.416
2018 McClintock MA, Dix CI, Johnson CM, McLaughlin SH, Maizels RJ, Hoang HT, Bullock SL. RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs. Elife. 7. PMID 29944118 DOI: 10.7554/Elife.36312  0.335
2017 Baumbach J, Murthy A, McClintock MA, Dix CI, Zalyte R, Hoang HT, Bullock SL. Lissencephaly-1 is a context-dependent regulator of the human dynein complex. Elife. 6. PMID 28406398 DOI: 10.7554/eLife.21768  0.424
2017 Mofatteh M, Bullock SL. SnapShot: Subcellular mRNA Localization. Cell. 169: 178-178.e1. PMID 28340345 DOI: 10.1016/j.cell.2017.03.004  0.313
2017 Hoang HT, Schlager MA, Carter AP, Bullock SL. DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28196890 DOI: 10.1073/pnas.1620141114  0.562
2016 Port F, Bullock SL. Creating Heritable Mutations in Drosophila with CRISPR-Cas9. Methods in Molecular Biology (Clifton, N.J.). 1478: 145-160. PMID 27730579 DOI: 10.1007/978-1-4939-6371-3_7  0.306
2015 Rossor AM, Oates EC, Salter HK, Liu Y, Murphy SM, Schule R, Gonzalez MA, Scoto M, Phadke R, Sewry CA, Houlden H, Jordanova A, Tournev I, Chamova T, Litvinenko I, ... ... Bullock SL, et al. Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2. Brain : a Journal of Neurology. 138: 293-310. PMID 25497877 DOI: 10.1093/Brain/Awu356  0.415
2014 Schlager MA, Hoang HT, Urnavicius L, Bullock SL, Carter AP. In vitro reconstitution of a highly processive recombinant human dynein complex. The Embo Journal. 33: 1855-68. PMID 24986880 DOI: 10.15252/embj.201488792  0.396
2014 Hain D, Langlands A, Sonnenberg HC, Bailey C, Bullock SL, Müller HA. The Drosophila MAST kinase Drop out is required to initiate membrane compartmentalisation during cellularisation and regulates dynein-based transport. Development (Cambridge, England). 141: 2119-30. PMID 24803657 DOI: 10.1242/dev.104711  0.377
2014 Soundararajan HC, Bullock SL. The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA. Elife. 3: e01596. PMID 24737859 DOI: 10.7554/eLife.01596  0.458
2014 Jambor H, Mueller S, Bullock SL, Ephrussi A. A stem-loop structure directs oskar mRNA to microtubule minus ends. Rna (New York, N.Y.). 20: 429-39. PMID 24572808 DOI: 10.1261/Rna.041566.113  0.346
2013 Sanghavi P, Laxani S, Li X, Bullock SL, Gonsalvez GB. Dynein associates with oskar mRNPs and is required for their efficient net plus-end localization in Drosophila oocytes. Plos One. 8: e80605. PMID 24244700 DOI: 10.1371/Journal.Pone.0080605  0.446
2013 Dix CI, Soundararajan HC, Dzhindzhev NS, Begum F, Suter B, Ohkura H, Stephens E, Bullock SL. Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs. The Journal of Cell Biology. 202: 479-94. PMID 23918939 DOI: 10.1083/jcb.201211052  0.455
2013 Liu Y, Salter HK, Holding AN, Johnson CM, Stephens E, Lukavsky PJ, Walshaw J, Bullock SL. Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein. Genes & Development. 27: 1233-46. PMID 23723415 DOI: 10.1101/Gad.212381.112  0.42
2012 Amrute-Nayak M, Bullock SL. Single-molecule assays reveal that RNA localization signals regulate dynein-dynactin copy number on individual transcript cargoes. Nature Cell Biology. 14: 416-23. PMID 22366687 DOI: 10.1038/ncb2446  0.424
2012 Bullock SL. Messengers, motors and mysteries: sorting of eukaryotic mRNAs by cytoskeletal transport. Biochemical Society Transactions. 39: 1161-5. PMID 21936782 DOI: 10.1042/BST0391161  0.437
2010 Bianco A, Dienstbier M, Salter HK, Gatto G, Bullock SL. Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis. Current Biology : Cb. 20: 1487-92. PMID 20691595 DOI: 10.1016/j.cub.2010.07.016  0.447
2010 Bullock SL, Ringel I, Ish-Horowicz D, Lukavsky PJ. A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nature Structural & Molecular Biology. 17: 703-9. PMID 20473315 DOI: 10.1038/Nsmb.1813  0.616
2010 Li X, Kuromi H, Briggs L, Green DB, Rocha JJ, Sweeney ST, Bullock SL. Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling. The Embo Journal. 29: 992-1006. PMID 20111007 DOI: 10.1038/emboj.2009.410  0.372
2009 Dienstbier M, Boehl F, Li X, Bullock SL. Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor. Genes & Development. 23: 1546-58. PMID 19515976 DOI: 10.1101/gad.531009  0.434
2009 Navarro C, Bullock S, Lehmann R. Altered dynein-dependent transport in piRNA pathway mutants. Proceedings of the National Academy of Sciences of the United States of America. 106: 9691-6. PMID 19478063 DOI: 10.1073/pnas.0903837106  0.326
2007 Bullock SL. Translocation of mRNAs by molecular motors: think complex? Seminars in Cell & Developmental Biology. 18: 194-201. PMID 17324596 DOI: 10.1016/j.semcdb.2007.01.004  0.42
2006 Bullock SL, Nicol A, Gross SP, Zicha D. Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity. Current Biology : Cb. 16: 1447-52. PMID 16860745 DOI: 10.1016/J.Cub.2006.05.055  0.463
2004 Hughes JR, Bullock SL, Ish-Horowicz D. Inscuteable mRNA localization is dynein-dependent and regulates apicobasal polarity and spindle length in Drosophila neuroblasts. Current Biology : Cb. 14: 1950-6. PMID 15530398 DOI: 10.1016/J.Cub.2004.10.022  0.642
2004 Bullock SL, Stauber M, Prell A, Hughes JR, Ish-Horowicz D, Schmidt-Ott U. Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution. Development (Cambridge, England). 131: 4251-61. PMID 15280214 DOI: 10.1242/Dev.01289  0.557
2003 Bullock SL, Zicha D, Ish-Horowicz D. The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. The Embo Journal. 22: 2484-94. PMID 12743042 DOI: 10.1093/emboj/cdg230  0.645
2002 Bullock SL, Ish-Horowicz D. Cell polarity: Oskar seeks PARtner for a stable relationship. Nature Cell Biology. 4: E117-8. PMID 11988750 DOI: 10.1038/Ncb0502-E117  0.572
Low-probability matches (unlikely to be authored by this person)
2023 Salvador-Garcia D, Jin L, Hensley A, Gölcük M, Gallaud E, Chaaban S, Port F, Vagnoni A, Planelles-Herrero VJ, McClintock MA, Derivery E, Carter AP, Giet R, Gür M, Yildiz A, ... Bullock SL, et al. A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression. Biorxiv : the Preprint Server For Biology. PMID 37577480 DOI: 10.1101/2023.08.03.551815  0.281
2015 Rossor AM, Oates EC, Salter HK, Liu Y, Murphy SM, Schule R, Gonzales MA, Scoto M, Phadke R, Sewry CA, Houlden H, Jordanova A, Tournev I, Chamova T, Litvinenko I, ... ... Bullock SL, et al. Reply: The p.Ser107Leu in BICD2 is a mutation 'hot spot' causing distal spinal muscular atrophy. Brain : a Journal of Neurology. PMID 26063657 DOI: 10.1093/brain/awv160  0.265
2018 Vagnoni A, Bullock SL. A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons. Current Biology : Cb. 28: 1265-1272.e4. PMID 29606421 DOI: 10.1016/j.cub.2018.02.048  0.264
2009 Holt CE, Bullock SL. Subcellular mRNA localization in animal cells and why it matters. Science (New York, N.Y.). 326: 1212-6. PMID 19965463 DOI: 10.1126/science.1176488  0.259
2002 Houzelstein D, Bullock SL, Lynch DE, Grigorieva EF, Wilson VA, Beddington RSP. Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4 Molecular and Cellular Biology. 22: 3794-3802. PMID 11997514 DOI: 10.1128/MCB.22.11.3794-3802.2002  0.254
2005 Snee MJ, Arn EA, Bullock SL, Macdonald PM. Recognition of the bcd mRNA localization signal in Drosophila embryos and ovaries Molecular and Cellular Biology. 25: 1501-1510. PMID 15684399 DOI: 10.1128/MCB.25.4.1501-1510.2005  0.248
2003 McLaughlin D, Karlsson F, Tian N, Pratt T, Bullock SL, Wilson VA, Price DJ, Mason JO. Specific modification of heparan sulphate is required for normal cerebral cortical development. Mechanisms of Development. 120: 1481-8. PMID 14654220 DOI: 10.1016/J.Mod.2003.08.008  0.218
2020 Bullock SL, Visa N, Pederson T. Meeting report - Nuclear and cytoplasmic molecular machines at work. Journal of Cell Science. 133. PMID 32253357 DOI: 10.1242/Jcs.245134  0.194
2001 Bullock SL, Johnson TM, Bao Q, Hughes RC, Winyard PJ, Woolf AS. Galectin-3 modulates ureteric bud branching in organ culture of the developing mouse kidney. Journal of the American Society of Nephrology : Jasn. 12: 515-23. PMID 11181799  0.192
2015 Vagnoni A, Hoffmann PC, Bullock SL. Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons. Journal of Cell Science. PMID 26598558 DOI: 10.1242/jcs.179184  0.177
2015 Port F, Muschalik N, Bullock SL. Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research. G3 (Bethesda, Md.). 5: 1493-502. PMID 25999583 DOI: 10.1534/g3.115.019083  0.176
2016 Vagnoni A, Bullock SL. A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing. Nature Protocols. 11: 1711-23. PMID 27560175 DOI: 10.1038/nprot.2016.112  0.176
2016 Port F, Bullock SL. Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs. Nature Methods. 13: 852-4. PMID 27595403 DOI: 10.1038/nmeth.3972  0.166
2014 Port F, Chen HM, Lee T, Bullock SL. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 111: E2967-76. PMID 25002478 DOI: 10.1073/Pnas.1405500111  0.149
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932  0.099
2023 Bullock S, Hoolohan C, Larkin A. Accelerating shipping decarbonisation: A case study on UK shore power. Heliyon. 9: e17475. PMID 37539144 DOI: 10.1016/j.heliyon.2023.e17475  0.042
2002 Goetinck PF, Papaionnou G, Rossant J, Tam P, Anderson K, Hastie N, Soriano P, Bullock S, Rodriguez T, Dunwoodie S, Wilson V, Thomas P, Conlon F, Pevney L. Remembering Rosa Beddington--a tribute from her friends and colleagues Developmental Dynamics : An Official Publication of the American Association of Anatomists. 223: 3-11. PMID 11803565 DOI: 10.1002/Dvdy.10053  0.016
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