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Eugene F Douglass, Jr. - Publications

Affiliations: 
2014 Yale University, New Haven, CT 
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hu LZ, Douglass E, Turunen M, Pampou S, Grunn A, Realubit R, Antolin AA, Wang ALE, Li H, Subramaniam P, Karan C, Alvarez M, Califano A. Elucidating Compound Mechanism of Action and Polypharmacology with a Large-scale Perturbational Profile Compendium. Biorxiv : the Preprint Server For Biology. PMID 37873470 DOI: 10.1101/2023.10.08.561457  0.759
2023 Mundi PS, Dela Cruz FS, Grunn A, Diolaiti D, Mauguen A, Rainey AR, Guillan K, Siddiquee A, You D, Realubit R, Karan C, Ortiz MV, Douglass EF, Accordino M, Mistretta S, et al. A transcriptome-based precision oncology platform for patient-therapy alignment in a diverse set of treatment resistant malignancies. Cancer Discovery. PMID 37061969 DOI: 10.1158/2159-8290.CD-22-1020  0.751
2023 Hughes EA, Zieliński R, Ray AE, Priebe W, Douglass EF. Development of a Novel Tool to Demystify Drug Distribution at Tissue-Blood Barriers. Chembiochem : a European Journal of Chemical Biology. e202200804. PMID 36951632 DOI: 10.1002/cbic.202200804  0.709
2022 Vasciaveo A, Arriaga JM, Nunes de Almeida F, Zou M, Douglass EF, Picech F, Shibata M, Rodriguez-Calero A, de Brot S, Mitrofanova A, Chua CW, Karan C, Realubit R, Pampou S, Kim JY, et al. OncoLoop: A network-based precision cancer medicine framework. Cancer Discovery. PMID 36374194 DOI: 10.1158/2159-8290.CD-22-0342  0.749
2022 Douglass EF, Allaway RJ, Szalai B, Wang W, Tian T, Fernández-Torras A, Realubit R, Karan C, Zheng S, Pessia A, Tanoli Z, Jafari M, Wan F, Li S, Xiong Y, et al. A community challenge for a pancancer drug mechanism of action inference from perturbational profile data. Cell Reports. Medicine. 3: 100492. PMID 35106508 DOI: 10.1016/j.xcrm.2021.100492  0.751
2021 Scotto L, Kinahan C, Douglass E, Deng C, Safari M, Casadei B, Marchi E, Lue JK, Montanari F, Falchi L, Qiao C, Renu N, Bates SE, Califano A, O'Connor OA. TARGETING THE T-CELL LYMPHOMA EPIGENOME INDUCES CELL DEATH, CANCER TESTES ANTIGENS, IMMUNE MODULATORY SIGNALING PATHWAYS. Molecular Cancer Therapeutics. PMID 34108263 DOI: 10.1158/1535-7163.MCT-20-0377  0.742
2021 Douglass EF, Spiegel DA. Comment on a suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by heterobifunctional ligands. The Journal of Biological Chemistry. 296: 100331. PMID 33837728 DOI: 10.1016/j.jbc.2021.100331  0.722
2021 Paull EO, Aytes A, Jones SJ, Subramaniam PS, Giorgi FM, Douglass EF, Tagore S, Chu B, Vasciaveo A, Zheng S, Verhaak R, Abate-Shen C, Alvarez MJ, Califano A. A modular master regulator landscape controls cancer transcriptional identity. Cell. PMID 33434495 DOI: 10.1016/j.cell.2020.11.045  0.741
2020 Douglass EF. Bridging "Big Data" and Mechanistic Insight To Enable Precision Medicine. Chembiochem : a European Journal of Chemical Biology. PMID 32865878 DOI: 10.1002/cbic.202000494  0.685
2020 Scotto L, Kinahan C, Casadei B, Mangone M, Douglass E, Vundavalli MV, Marchi E, Ma H, George C, Montanari F, Califano A, O'Connor OA. Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers. Genes, Chromosomes & Cancer. PMID 32614991 DOI: 10.1002/Gcc.22884  0.731
2020 Laise P, Bosker G, Sun X, Shen Y, Douglass EF, Karan C, Realubit RB, Pampou S, Califano A, Alvarez MJ. The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States. Biorxiv : the Preprint Server For Biology. PMID 32511361 DOI: 10.1101/2020.05.12.091256  0.745
2018 Ding H, Douglass EF, Sonabend AM, Mela A, Bose S, Gonzalez C, Canoll PD, Sims PA, Alvarez MJ, Califano A. Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm. Nature Communications. 9: 1471. PMID 29662057 DOI: 10.1038/S41467-018-03843-3  0.733
2017 Douglass EF, Avci H, Boy R, Rojas OJ, Kotek R. A Review of Cellulose and Cellulose Blends for Preparation of Bio-derived and Conventional Membranes, Nanostructured Thin Films, and Composites Polymer Reviews. 58: 102-163. DOI: 10.1080/15583724.2016.1269124  0.738
2015 Santori FR, Huang P, van de Pavert SA, Douglass EF, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97. PMID 25651181 DOI: 10.1016/J.Cmet.2015.01.004  0.735
2014 McEnaney PJ, Fitzgerald KJ, Zhang AX, Douglass EF, Shan W, Balog A, Kolesnikova MD, Spiegel DA. Chemically synthesized molecules with the targeting and effector functions of antibodies. Journal of the American Chemical Society. 136: 18034-43. PMID 25514603 DOI: 10.1021/Ja509513C  0.725
2014 Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, et al. Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules. Chemical Science (Royal Society of Chemistry : 2010). 5: 2311-2317. PMID 25379167 DOI: 10.1039/C4Sc00484A  0.743
2013 Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF, Spiegel DA. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators. Acs Chemical Biology. 8: 2404-11. PMID 24053626 DOI: 10.1021/Cb4004942  0.747
2013 Wang T, Douglass EF, Fitzgerald KJ, Spiegel DA. A "turn-on" fluorescent sensor for methylglyoxal. Journal of the American Chemical Society. 135: 12429-33. PMID 23931147 DOI: 10.1021/Ja406077J  0.737
2013 Douglass EF, Miller CJ, Sparer G, Shapiro H, Spiegel DA. A comprehensive mathematical model for three-body binding equilibria. Journal of the American Chemical Society. 135: 6092-9. PMID 23544844 DOI: 10.1021/Ja311795D  0.739
2013 Zhu Y, Douglass E, Theyson T, Hogan R, Kotek R. Cellulose and soy proteins based membrane networks Macromolecular Symposia. 329: 70-86. DOI: 10.1002/Masy.201300032  0.738
2008 Douglass EF, Driscoll PF, Liu D, Burnham NA, Lambert CR, McGimpsey WG. Effect of electrode roughness on the capacitive behavior of self-assembled monolayers. Analytical Chemistry. 80: 7670-7. PMID 18811215 DOI: 10.1021/Ac800521Z  0.716
2008 Driscoll PF, Douglass EF, Phewluangdee M, Soto ER, Cooper CG, Macdonald JC, Lambert CR, McGimpsey WG. Photocurrent generation in noncovalently assembled multilayered thin films. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 5140-5. PMID 18393555 DOI: 10.1021/La703586E  0.727
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