Morgan Sheng

Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Synaptic Plasticity
"Morgan Sheng"
Mean distance: 12.86 (cluster 11)
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Dejanovic B, Sheng M, Hanson JE. (2023) Targeting synapse function and loss for treatment of neurodegenerative diseases. Nature Reviews. Drug Discovery
Farsi Z, Nicolella A, Simmons SK, et al. (2023) Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron
Bygrave AM, Sengupta A, Jackert EP, et al. (2023) Btbd11 supports cell-type-specific synaptic function. Cell Reports. 42: 112591
Aryal S, Bonanno K, Song B, et al. (2023) Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model. Cell Reports. 42: 112497
Zhou J, Wade SD, Graykowski D, et al. (2023) The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration. Science Translational Medicine. 15: eadf0141
Herzog LE, Wang L, Yu E, et al. (2023) Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients. Translational Psychiatry. 13: 92
Dejanovic B, Wu T, Tsai MC, et al. (2022) Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models. Nature Aging. 2: 837-850
Wang Y, Kerrisk Campbell M, Tom I, et al. (2020) PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function. Scientific Reports. 10: 10951
Vogl AM, Phu L, Becerra R, et al. (2020) Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nature Structural & Molecular Biology
Hanson JE, Ma K, Elstrott J, et al. (2020) GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. Cell Reports. 30: 381-396.e4
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