Frédéric Saudou, PhD
Affiliations: | 1999-2013 | Inserm U1005 | Institut Curie, Bures-sur-Yvette, Île-de-France, France |
| 2013- | Grenoble Institute of Neurosciences | Université Grenoble Alpes, INSERM |
Area:
Huntington's disease, intracellular dynamics, axonal transportWebsite:
https://neurosciences.ujf-grenoble.fr/search/team-saudou-intracellular-dynamics-neurodegeneration?language=enGoogle:
"Frédéric Saudou"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| René Hen | grad student | 1989-1993 | Université Strasbourg |
| Jean-Louis Mandel | post-doc | 1994-1996 | Institut de Biologie Moléculaire et Cellulaire (IGBMC) |
| Michael E. Greenberg | post-doc | 1996-1999 | Harvard Medical School - Boston Children's Hospital |
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Publications
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| Migazzi A, Scaramuzzino C, Anderson EN, et al. (2021) Huntingtin-mediated axonal transport requires arginine methylation by PRMT6. Cell Reports. 35: 108980 |
| Virlogeux A, Scaramuzzino C, Lenoir S, et al. (2021) Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice. Science Advances. 7 |
| Vitet H, Brandt V, Saudou F. (2020) Traffic signaling: new functions of huntingtin and axonal transport in neurological disease. Current Opinion in Neurobiology. 63: 122-130 |
| Kacher R, Lamazière A, Heck N, et al. (2019) CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease. Brain : a Journal of Neurology |
| Kacher R, Kappes V, Lamazière A, et al. (2018) I13 Striatal regulation of cholesterol metabolism by CYP46A1 is associated with multiple benefits in huntington’s disease knock-in mice models Journal of Neurology, Neurosurgery, and Psychiatry. 89 |
| Migazzi A, Tripathy D, Scaramuzzino C, et al. (2018) A14 Arginine methylation of huntingtin is a novel post-translational modification that impacts huntington’s disease pathogenesis Journal of Neurology, Neurosurgery, and Psychiatry. 89 |
| Kratter IH, Zahed H, Lau A, et al. (2016) Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation |
| Saudou F, Humbert S. (2016) The Biology of Huntingtin. Neuron. 89: 910-26 |
| Ochaba J, Lukacsovich T, Csikos G, et al. (2014) Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: 16889-94 |
| Drouet V, Ruiz M, Zala D, et al. (2014) Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells. Plos One. 9: e99341 |