Todd D. Gould, M.D.
Affiliations: | Departments of Psychiatry, Pharmacology, and Anatomy & Neurobiology | University of Maryland School of Medicine, Baltimore, MD, United States |
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Sign in to add mentorIrving I. Gottesman | grad student | UVA | |
Husseini K. Manji | post-doc | National Institute of Mental Health (NIMH) |
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Publications
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Hasin N, Riggs LM, Shekhtman T, et al. (2022) Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder. Molecular Psychiatry |
Highland JN, Morris PJ, Konrath KM, et al. (2022) Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523 |
Troppoli TA, Zanos P, Georgiou P, et al. (2021) Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. Biological Psychiatry |
Highland JN, Farmer CA, Zanos P, et al. (2021) Sex-dependent metabolism of ketamine and ()-hydroxynorketamine in mice and humans. Journal of Psychopharmacology (Oxford, England). 2698811211064922 |
Hess EM, Riggs LM, Michaelides M, et al. (2021) Mechanisms of Ketamine and its Metabolites as Antidepressants. Biochemical Pharmacology. 114892 |
Riggs LM, An X, Pereira EFR, et al. (2021) (R,S)-ketamine and (2R,6R)-hydroxynorketamine differentially affect memory as a function of dosing frequency. Translational Psychiatry. 11: 583 |
Morris PJ, Burke RD, Sharma AK, et al. (2021) A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801. Neurotoxicology and Teratology. 106993 |
Highland JN, Zanos P, Riggs LM, et al. (2021) Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791 |
Riggs LM, Gould TD. (2021) Ketamine and the Future of Rapid-Acting Antidepressants. Annual Review of Clinical Psychology |
Elmer GI, Tapocik JD, Mayo CL, et al. (2020) Ketamine metabolite (2R,6R)-hydroxynorketamine reverses behavioral despair produced by adolescent trauma. Pharmacology, Biochemistry, and Behavior. 172973 |