Charles Askew, PhD
Affiliations: | 2008-2015 | Neuroscience | University of Virginia, Charlottesville, VA |
| 2011-2015 | Otolaryngology | Harvard - Boston Children's Hospital | |
| 2015- | Gene Therapy Center | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Sensory NeuroscienceGoogle:
"Charles Askew"Mean distance: 16.03 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Michael Anne Gratton | research assistant | 2003-2008 | Penn |
| James C. Saunders | research assistant | 2005-2008 | Penn |
| Jeffrey R. Holt | grad student | 2008-2015 | University of Virginia, Harvard |
| Richard J. Samulski | post-doc | 2015- | UNC Chapel Hill |
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Publications
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| Casey G, Askew C, Brimble MA, et al. (2020) Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues. Plos One. 15: e0242599 |
| Pei X, Shao W, Xing A, et al. (2020) Development of AAV Variants with Human Hepatocyte Tropism and Neutralizing Antibody Escape Capacity. Molecular Therapy. Methods & Clinical Development. 18: 259-268 |
| Askew C, Chien WW. (2020) Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges. Hearing Research. 107947 |
| Pei X, Shao W, Xing A, et al. (2020) Development of AAV Variants with Human Hepatocyte Tropism and Neutralizing Antibody Escape Capacity Molecular Therapy - Methods & Clinical Development. 18: 259-268 |
| Shao W, Pei X, Cui C, et al. (2019) Superior human hepatocyte transduction with adeno-associated virus vector serotype 7. Gene Therapy |
| Pappa AK, Hutson KA, Scott WC, et al. (2019) Hair Cell and Neural Contributions to the Cochlear Summating Potential. Journal of Neurophysiology |
| Avenarius MR, Jung JY, Askew C, et al. (2018) Grxcr2 is required for stereocilia morphogenesis in the cochlea. Plos One. 13: e0201713 |
| Pan B, Askew C, Galvin A, et al. (2017) Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c. Nature Biotechnology |
| Landegger LD, Pan B, Askew C, et al. (2017) A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. Nature Biotechnology |
| Askew C, Rochat C, Pan B, et al. (2015) Tmc gene therapy restores auditory function in deaf mice. Science Translational Medicine. 7: 295ra108 |