Karen Gale - Publications

Affiliations: 
Georgetown University, Washington, DC 
Area:
neuropharmacology, epilepsy

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Vismer MS, Forcelli PA, Skopin MD, Gale K, Koubeissi MZ. The piriform, perirhinal, and entorhinal cortex in seizure generation. Frontiers in Neural Circuits. 9: 27. PMID 26074779 DOI: 10.3389/fncir.2015.00027  1
2015 Malkova L, Forcelli PA, Wellman LL, Dybdal D, Dubach MF, Gale K. Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5043-50. PMID 25810533 DOI: 10.1523/JNEUROSCI.4307-14.2015  1
2014 Ullrich L, Dumanis SB, Evans TM, Jeannotte AM, Leonard C, Rozzi SJ, Taylor CM, Gale K, Kanwal JS, Maguire-Zeiss KA, Wolfe BB, Forcelli PA. From student to steward: the Interdisciplinary Program in Neuroscience at Georgetown University as a case study in professional development during doctoral training. Medical Education Online. 19: 22623. PMID 28440177 DOI: 10.3402/meo.v19.22623  1
2014 Gutherz SB, Kulick CV, Soper C, Kondratyev A, Gale K, Forcelli PA. Brief postnatal exposure to phenobarbital impairs passive avoidance learning and sensorimotor gating in rats. Epilepsy & Behavior : E&B. 37: 265-9. PMID 25112558 DOI: 10.1016/j.yebeh.2014.07.010  1
2014 Avanzini G, Forcelli PA, Gale K. Are there really "epileptogenic" mechanisms or only corruptions of "normal" plasticity? Advances in Experimental Medicine and Biology. 813: 95-107. PMID 25012370 DOI: 10.1007/978-94-017-8914-1_8  1
2014 Ullrich L, Dumanis SB, Evans TM, Jeannotte AM, Leonard C, Rozzi SJ, Taylor CM, Gale K, Kanwal JS, Maguire-Zeiss KA, Wolfe BB, Forcelli PA. From student to steward: the Interdisciplinary Program in Neuroscience at Georgetown University as a case study in professional development during doctoral training. Medical Education Online. 19: 22623. PMID 25005356  1
2014 Forcelli PA, Palchik G, Leath T, DesJardin JT, Gale K, Malkova L. Memory loss in a nonnavigational spatial task after hippocampal inactivation in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 111: 4315-20. PMID 24591610 DOI: 10.1073/pnas.1320562111  1
2013 Forcelli PA, Kalikhman D, Gale K. Delayed effect of craniotomy on experimental seizures in rats. Plos One. 8: e81401. PMID 24324691 DOI: 10.1371/journal.pone.0081401  1
2013 Forcelli PA, Soper C, Duckles A, Gale K, Kondratyev A. Melatonin potentiates the anticonvulsant action of phenobarbital in neonatal rats. Epilepsy Research. 107: 217-23. PMID 24206906 DOI: 10.1016/j.eplepsyres.2013.09.013  1
2013 Besio WG, Makeyev O, Medvedev A, Gale K. Effects of transcranial focal electrical stimulation via tripolar concentric ring electrodes on pentylenetetrazole-induced seizures in rats. Epilepsy Research. 105: 42-51. PMID 23290195 DOI: 10.1016/j.eplepsyres.2012.12.002  1
2013 DesJardin JT, Holmes AL, Forcelli PA, Cole CE, Gale JT, Wellman LL, Gale K, Malkova L. Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 150-5. PMID 23283329 DOI: 10.1523/JNEUROSCI.2924-12.2013  1
2013 Dybdal D, Forcelli PA, Dubach M, Oppedisano M, Holmes A, Malkova L, Gale K. Topography of dyskinesias and torticollis evoked by inhibition of substantia nigra pars reticulata. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 460-8. PMID 23115112 DOI: 10.1002/mds.25215  1
2012 Holmes AL, Forcelli PA, DesJardin JT, Decker AL, Teferra M, West EA, Malkova L, Gale K. Superior colliculus mediates cervical dystonia evoked by inhibition of the substantia nigra pars reticulata. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13326-32. PMID 22993447 DOI: 10.1523/JNEUROSCI.2295-12.2012  1
2012 West EA, Forcelli PA, Murnen AT, McCue DL, Gale K, Malkova L. Transient inactivation of basolateral amygdala during selective satiation disrupts reinforcer devaluation in rats. Behavioral Neuroscience. 126: 563-74. PMID 22845705 DOI: 10.1037/a0029080  1
2012 Forcelli PA, Sweeney CT, Kammerich AD, Lee BC, Rubinson LH, Kayinamura YP, Gale K, Rubinson JF. Histocompatibility and in vivo signal throughput for PEDOT, PEDOP, P3MT, and polycarbazole electrodes. Journal of Biomedical Materials Research. Part A. 100: 3455-62. PMID 22821813 DOI: 10.1002/jbm.a.34285  1
2012 Forcelli PA, Janssen MJ, Vicini S, Gale K. Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development. Annals of Neurology. 72: 363-72. PMID 22581672 DOI: 10.1002/ana.23600  1
2012 Forcelli PA, Soper C, Lakhkar A, Gale K, Kondratyev A. Anticonvulsant effect of retigabine during postnatal development in rats. Epilepsy Research. 101: 135-40. PMID 22483539 DOI: 10.1016/j.eplepsyres.2012.03.006  1
2012 Bhardwaj SK, Forcelli PA, Palchik G, Gale K, Srivastava LK, Kondratyev A. Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology. 62: 2337-45. PMID 22366076 DOI: 10.1016/j.neuropharm.2012.02.001  1
2012 Forcelli PA, Kozlowski R, Snyder C, Kondratyev A, Gale K. Effects of neonatal antiepileptic drug exposure on cognitive, emotional, and motor function in adult rats. The Journal of Pharmacology and Experimental Therapeutics. 340: 558-66. PMID 22129597 DOI: 10.1124/jpet.111.188862  1
2011 Forcelli PA, Kim J, Kondratyev A, Gale K. Pattern of antiepileptic drug-induced cell death in limbic regions of the neonatal rat brain. Epilepsia. 52: e207-11. PMID 22050285 DOI: 10.1111/j.1528-1167.2011.03297.x  1
2011 West EA, DesJardin JT, Gale K, Malkova L. Transient inactivation of orbitofrontal cortex blocks reinforcer devaluation in macaques. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15128-35. PMID 22016546 DOI: 10.1523/JNEUROSCI.3295-11.2011  1
2011 Laufs H, Richardson MP, Salek-Haddadi A, Vollmar C, Duncan JS, Gale K, Lemieux L, Löscher W, Koepp MJ. Converging PET and fMRI evidence for a common area involved in human focal epilepsies. Neurology. 77: 904-10. PMID 21849655 DOI: 10.1212/WNL.0b013e31822c90f2  1
2011 Crowe SL, Tsukerman S, Gale K, Jorgensen TJ, Kondratyev AD. Phosphorylation of histone H2A.X as an early marker of neuronal endangerment following seizures in the adult rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7648-56. PMID 21613478 DOI: 10.1523/JNEUROSCI.0092-11.2011  1
2011 Forcelli PA, Gale K, Kondratyev A. Early postnatal exposure of rats to lamotrigine, but not phenytoin, reduces seizure threshold in adulthood. Epilepsia. 52: e20-2. PMID 21463268 DOI: 10.1111/j.1528-1167.2010.02971.x  1
2011 Malkova L, Kozikowski AP, Gale K. The effects of huperzine A and IDRA 21 on visual recognition memory in young macaques. Neuropharmacology. 60: 1262-8. PMID 21185313 DOI: 10.1016/j.neuropharm.2010.12.018  1
2011 West EA, Forcelli PA, Murnen A, Gale K, Malkova L. A visual, position-independent instrumental reinforcer devaluation task for rats. Journal of Neuroscience Methods. 194: 297-304. PMID 21093482 DOI: 10.1016/j.jneumeth.2010.11.004  1
2010 Besio WG, Gale KN, Medvedev AV. Possible therapeutic effects of transcutaneous electrical stimulation via concentric ring electrodes. Epilepsia. 51: 85-7. PMID 20618408 DOI: 10.1111/j.1528-1167.2010.02617.x  1
2010 Forcelli PA, Janssen MJ, Stamps LA, Sweeney C, Vicini S, Gale K. Therapeutic strategies to avoid long-term adverse outcomes of neonatal antiepileptic drug exposure. Epilepsia. 51: 18-23. PMID 20618394 DOI: 10.1111/j.1528-1167.2010.02603.x  1
2010 Kim J, Gale K, Kondratyev A. Effects of repeated minimal electroshock seizures on NGF, BDNF and FGF-2 protein in the rat brain during postnatal development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 28: 227-32. PMID 20170723 DOI: 10.1016/j.ijdevneu.2010.02.003  1
2009 Schachter SC, Guttag J, Schiff SJ, Schomer DL. Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit. Epilepsy & Behavior : E&B. 16: 3-46. PMID 19780225 DOI: 10.1016/j.yebeh.2009.06.028  1
2009 Conti G, Gale K, Kondratyev A. Immunohistochemical evaluation of the protein expression of nerve growth factor and its TrkA receptor in rat limbic regions following electroshock seizures. Neuroscience Research. 65: 201-9. PMID 19596387 DOI: 10.1016/j.neures.2009.07.001  1
2007 Kim JS, Kondratyev A, Tomita Y, Gale K. Neurodevelopmental impact of antiepileptic drugs and seizures in the immature brain. Epilepsia. 48: 19-26. PMID 17910577 DOI: 10.1111/j.1528-1167.2007.01285.x  1
2007 Kim J, Kondratyev A, Gale K. Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy. The Journal of Pharmacology and Experimental Therapeutics. 323: 165-73. PMID 17636003 DOI: 10.1124/jpet.107.126250  1
2007 Katz I, Kim J, Gale K, Kondratyev A. Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain. The Journal of Pharmacology and Experimental Therapeutics. 322: 494-500. PMID 17483293 DOI: 10.1124/jpet.107.123133  1
2005 Wellman LL, Gale K, Malkova L. GABAA-mediated inhibition of basolateral amygdala blocks reward devaluation in macaques. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4577-86. PMID 15872105 DOI: 10.1523/JNEUROSCI.2257-04.2005  1
2005 Fornai F, Busceti CL, Kondratyev A, Gale K. AMPA receptor desensitization as a determinant of vulnerability to focally evoked status epilepticus. The European Journal of Neuroscience. 21: 455-63. PMID 15673444 DOI: 10.1111/j.1460-9568.2005.03873.x  1
2004 Kondratyev A, Gale K. Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death. Brain Research. Molecular Brain Research. 121: 86-94. PMID 14969739 DOI: 10.1016/j.molbrainres.2003.11.005  1
2003 Richardson KA, Gluckman BJ, Weinstein SL, Glosch CE, Moon JB, Gwinn RP, Gale K, Schiff SJ. In vivo modulation of hippocampal epileptiform activity with radial electric fields. Epilepsia. 44: 768-77. PMID 12790889 DOI: 10.1046/j.1528-1157.2003.35402.x  1
2003 Malkova L, Barrow KV, Lower LL, Gale K. Decreased social interactions in monkeys after unilateral blockade of GABAA receptors in the basolateral amygdala Annals of the New York Academy of Sciences. 985: 540-541.  1
2002 Kondratyev A, Ved R, Gale K. The effects of repeated minimal electroconvulsive shock exposure on levels of mRNA encoding fibroblast growth factor-2 and nerve growth factor in limbic regions. Neuroscience. 114: 411-6. PMID 12204210 DOI: 10.1016/S0306-4522(02)00266-X  1
2002 Gwinn RP, Kondratyev A, Gale K. Time-dependent increase in basic fibroblast growth factor protein in limbic regions following electroshock seizures. Neuroscience. 114: 403-9. PMID 12204209 DOI: 10.1016/S0306-4522(02)00265-8  1
2002 Kondratyev A, Selby D, Gale K. Status epilepticus leads to the degradation of the endogenous inhibitor of caspase-activated DNase in rats. Neuroscience Letters. 319: 145-8. PMID 11834314 DOI: 10.1016/S0304-3940(02)00004-6  1
2001 Kondratyev A, Gale K. Temporal and spatial patterns of DNA fragmentation following focally or systemically-evoked status epilepticus in rats. Neuroscience Letters. 310: 13-6. PMID 11524146 DOI: 10.1016/S0304-3940(01)02055-9  1
2001 Kondratyev A, Sahibzada N, Gale K. Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Research. Molecular Brain Research. 91: 1-13. PMID 11457487 DOI: 10.1016/S0169-328X(01)00099-7  1
2000 Dybdal D, Gale K. Postural and anticonvulsant effects of inhibition of the rat subthalamic nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6728-33. PMID 10964979  1
2000 Doherty J, Gale K, Eagles DA. Evoked epileptiform discharges in the rat anterior piriform cortex: generation and local propagation. Brain Research. 861: 77-87. PMID 10751567 DOI: 10.1016/S0006-8993(00)02000-X  1
2000 Kondratyev A, Gale K. Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Research. Molecular Brain Research. 75: 216-24. PMID 10686342 DOI: 10.1016/S0169-328X(99)00292-2  1
1999 Walker BR, Easton A, Gale K. Regulation of limbic motor seizures by GABA and glutamate transmission in nucleus tractus solitarius. Epilepsia. 40: 1051-7. PMID 10448815 DOI: 10.1111/j.1528-1157.1999.tb00818.x  1
1999 Masco D, Sahibzada N, Switzer R, Gale K. Electroshock seizures protect against apoptotic hippocampal cell death induced by adrenalectomy. Neuroscience. 91: 1315-9. PMID 10391438 DOI: 10.1016/S0306-4522(98)00636-8  1
1998 New KC, Gale K, Martuza RL, Rabkin SD. Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase. Brain Research. Molecular Brain Research. 61: 121-35. PMID 9795182 DOI: 10.1016/S0169-328X(98)00203-4  1
1998 Cassidy RM, Gale K. Mediodorsal thalamus plays a critical role in the development of limbic motor seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9002-9. PMID 9787005  1
1997 Tortorella A, Halonen T, Sahibzada N, Gale K. A crucial role of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptors in piriform and perirhinal cortex for the initiation and propagation of limbic motor seizures. The Journal of Pharmacology and Experimental Therapeutics. 280: 1401-5. PMID 9067329  1
1997 Proctor MR, Fornai F, Afshar JK, Gale K. The role of nitric oxide in focally-evoked limbic seizures. Neuroscience. 76: 1231-6. PMID 9027881 DOI: 10.1016/S0306-4522(96)00390-9  1
1996 Pasini A, Tortorella A, Gale K. The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin. Brain Research. 724: 84-8. PMID 8816259 DOI: 10.1016/0006-8993(96)00291-0  1
1995 Gale K. Chemoconvulsant seizures: advantages of focally-evoked seizure models. Italian Journal of Neurological Sciences. 16: 17-25. PMID 7642347 DOI: 10.1007/BF02229070  1
1995 Meloni R, Gale K. Activation of tyrosine hydroxylase by haloperidol in fetal nigral transplants. Neuroreport. 6: 666-8. PMID 7605923  1
1994 Fornai F, Dybdal DJ, Proctor MR, Gale K. Focal intracerebral elevation of L-lactate is anticonvulsant. European Journal of Pharmacology. 254: R1-2. PMID 8013555 DOI: 10.1016/0014-2999(94)90473-1  1
1994 Halonen T, Tortorella A, Zrebeet H, Gale K. Posterior piriform and perirhinal cortex relay seizures evoked from the area tempestas: role of excitatory and inhibitory amino acid receptors. Brain Research. 652: 145-8. PMID 7953711 DOI: 10.1016/0006-8993(94)90328-X  1
1994 Follesa P, Gale K, Mocchetti I. Regional and temporal pattern of expression of nerve growth factor and basic fibroblast growth factor mRNA in rat brain following electroconvulsive shock. Experimental Neurology. 127: 37-44. PMID 7515352 DOI: 10.1006/exnr.1994.1077  1
1994 Karstaedt PJ, Kerasidis H, Pincus JH, Meloni R, Graham J, Gale K. Unilateral destruction of dopamine pathways increases ipsilateral striatal serotonin turnover in rats. Experimental Neurology. 126: 25-30. PMID 7512513 DOI: 10.1006/exnr.1994.1039  1
1993 Browning R, Maggio R, Sahibzada N, Gale K. Role of brainstem structures in seizures initiated from the deep prepiriform cortex of rats. Epilepsia. 34: 393-407. PMID 8504774  1
1993 Lanaud P, Maggio R, Gale K, Grayson DR. Temporal and spatial patterns of expression of c-fos, zif/268, c-jun and jun-B mRNAs in rat brain following seizures evoked focally from the deep prepiriform cortex. Experimental Neurology. 119: 20-31. PMID 8432348 DOI: 10.1006/exnr.1993.1003  1
1993 Maggio R, Lanaud P, Grayson DR, Gale K. Expression of c-fos mRNA following seizures evoked from an epileptogenic site in the deep prepiriform cortex: regional distribution in brain as shown by in situ hybridization. Experimental Neurology. 119: 11-9. PMID 8432343 DOI: 10.1006/exnr.1993.1002  1
1993 Gale K, Pazos A, Maggio R, Japikse K, Pritchard P. Blockade of GABA receptors in superior colliculus protects against focally evoked limbic motor seizures. Brain Research. 603: 279-83. PMID 8384921 DOI: 10.1016/0006-8993(93)91248-Q  1
1993 Prendiville S, Gale K. Anticonvulsant effect of fluoxetine on focally evoked limbic motor seizures in rats. Epilepsia. 34: 381-4. PMID 8384110  1
1992 Peterson CJ, Vinayak S, Pazos A, Gale K. A rodent model of focally evoked self-sustaining status epilepticus. European Journal of Pharmacology. 221: 151-5. PMID 1459187 DOI: 10.1016/0014-2999(92)90785-3  1
1992 Pasini A, Tortorella A, Gale K. Anticonvulsant effect of intranigral fluoxetine. Brain Research. 593: 287-90. PMID 1450936 DOI: 10.1016/0006-8993(92)91320-E  1
1992 Gale K, Zhong P, Miller LP, Murray TF. Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex. Epilepsy Research. Supplement. 8: 229-34. PMID 1384540  1
1992 Gale K. Subcortical structures and pathways involved in convulsive seizure generation. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 9: 264-77. PMID 1350593  1
1992 Gale K. Role of GABA in the genesis of chemoconvulsant seizures. Toxicology Letters. 64: 417-28. PMID 1335180 DOI: 10.1016/0378-4274(92)90215-6  1
1992 Riva MA, Gale K, Mocchetti I. Basic fibroblast growth factor mRNA increases in specific brain regions following convulsive seizures. Brain Research. Molecular Brain Research. 15: 311-8. PMID 1331686 DOI: 10.1016/0169-328X(92)90123-S  1
1992 Gale K. GABA and epilepsy: basic concepts from preclinical research. Epilepsia. 33: S3-12. PMID 1330509  1
1992 Gale K, Maggio R, Halonen T, Lanaud P, Grayson D. Regional changes in immediate early gene expression following focally-evoked limbic motor seizures. Epilepsy Research. Supplement. 9: 361-9. PMID 1285911  1
1991 Meloni R, Gale K. Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra. European Journal of Pharmacology. 209: 113-7. PMID 1839982 DOI: 10.1016/0014-2999(91)90020-Q  1
1991 Segovia J, Castro R, Notario V, Gale K. Transplants of fetal substantia nigra regulate glutamic acid decarboxylase gene expression in host striatal neurons. Brain Research. Molecular Brain Research. 10: 359-62. PMID 1656162 DOI: 10.1016/0169-328X(91)90097-H  1
1991 Maggio R, Sohn E, Gale K. Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models. Brain Research. 547: 1-6. PMID 1650283 DOI: 10.1016/0006-8993(91)90567-F  1
1990 Meloni R, Gale K. Pharmacological evidence for feedback regulation of dopamine metabolism in solid fetal substantia nigra transplants. The Journal of Pharmacology and Experimental Therapeutics. 253: 1259-64. PMID 2359027  1
1990 Wardas J, Graham J, Gale K. Evidence for a role of glycine in area tempestas for triggering convulsive seizures. European Journal of Pharmacology. 187: 59-66. PMID 2176981 DOI: 10.1016/0014-2999(90)90340-C  1
1990 Maggio R, Liminga U, Gale K. Selective stimulation of kainate but not quisqualate or NMDA receptors in substantia nigra evokes limbic motor seizures. Brain Research. 528: 223-30. PMID 2176910 DOI: 10.1016/0006-8993(90)91661-Y  1
1990 Meloni R, Gale K. Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum. Progress in Brain Research. 82: 467-71. PMID 2127112  1
1990 Segovia J, Tillakaratne NJ, Whelan K, Tobin AJ, Gale K. Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway. Brain Research. 529: 345-8. PMID 2126483 DOI: 10.1016/0006-8993(90)90849-7  1
1989 Massotti M, Gale K. Electroencephalographic evidence for a dose-related biphasic effect of morphine on bicuculline-induced seizures in the rat. Epilepsy Research. 4: 81-9. PMID 2792070 DOI: 10.1016/0920-1211(89)90012-0  1
1989 Maggio R, Gale K. Seizures evoked from area tempestas are subject to control by GABA and glutamate receptors in substantia nigra. Experimental Neurology. 105: 184-8. PMID 2568946 DOI: 10.1016/0014-4886(89)90118-0  1
1989 Gale K. GABA in epilepsy: the pharmacologic basis. Epilepsia. 30: S1-11. PMID 2548836  1
1989 Dean P, Gale K. Anticonvulsant action of GABA receptor blockade in the nigrotectal target region. Brain Research. 477: 391-5. PMID 2539235 DOI: 10.1016/0006-8993(89)91434-0  1
1989 Segovia J, Meloni R, Gale K. Effect of dopaminergic denervation and transplant-derived reinnervation on a marker of striatal GABAergic function. Brain Research. 493: 185-9. PMID 2505886 DOI: 10.1016/0006-8993(89)91015-9  1
1988 Franklin PH, Tripp ED, Zhang G, Gale K, Murray TF. Adenosine receptor activation blocks seizures induced by bicuculline methiodide in the rat prepiriform cortex. European Journal of Pharmacology. 150: 207-9. PMID 3402541 DOI: 10.1016/0014-2999(88)90773-X  1
1988 Jessop JJ, Gale K, Bayer BM. Time-dependent enhancement of lymphocyte activation by mitogens after exposure to isolation or water scheduling. Life Sciences. 43: 1133-40. PMID 2971850 DOI: 10.1016/0024-3205(88)90472-9  1
1988 Meloni R, Childs J, Gerogan F, Yurkofsky S, Gale K. Effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. Progress in Brain Research. 78: 457-61. PMID 2854639  1
1988 Gale K. Progression and generalization of seizure discharge: anatomical and neurochemical substrates. Epilepsia. 29: S15-34. PMID 2844521  1
1988 Bachus SE, Gale K. Differential effects of chronic treatment with chlorpromazine versus cocaine on behavioral responsiveness to nigral GABA receptor stimulation. Psychopharmacology. 95: 56-62. PMID 2838860 DOI: 10.1007/BF00212767  1
1988 Gunne LM, Bachus SE, Gale K. Oral movements induced by interference with nigral GABA neurotransmission: relationship to tardive dyskinesias. Experimental Neurology. 100: 459-69. PMID 2835254 DOI: 10.1016/0014-4886(88)90031-3  1
1987 Jessop JJ, Gale K, Bayer BM. Enhancement of rat lymphocyte proliferation after prolonged exposure to stress. Journal of Neuroimmunology. 16: 261-71. PMID 3624456 DOI: 10.1016/0165-5728(87)90080-4  1
1987 Kerasidis H, Wrathall JR, Gale K. Behavioral assessment of functional deficit in rats with contusive spinal cord injury. Journal of Neuroscience Methods. 20: 167-79. PMID 3600032 DOI: 10.1016/0165-0270(87)90048-3  1
1987 Garant DS, Gale K. Substantia nigra-mediated anticonvulsant actions: role of nigral output pathways. Experimental Neurology. 97: 143-59. PMID 3582559 DOI: 10.1016/0014-4886(87)90289-5  1
1987 Piredda S, Pavlick M, Gale K. Anticonvulsant effects of GABA elevation in the deep prepiriform cortex. Epilepsy Research. 1: 102-6. PMID 3504386 DOI: 10.1016/0920-1211(87)90014-3  1
1986 Bachus SE, Gale K. Muscimol microinfused into the nigrotegmental target area blocks selected components of behavior elicited by amphetamine or cocaine. Naunyn-Schmiedeberg's Archives of Pharmacology. 333: 143-8. PMID 3748195 DOI: 10.1007/BF00506517  1
1986 Garant D, Gale K. Intranigral muscimol attenuates electrographic signs of seizure activity induced by intravenous bicuculline in rats. European Journal of Pharmacology. 124: 365-9. PMID 3732385 DOI: 10.1016/0014-2999(86)90242-6  1
1986 Piredda S, Gale K. Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex. Brain Research. 377: 205-10. PMID 2873868 DOI: 10.1016/0006-8993(86)90859-0  1
1986 Garant DS, Iadarola MJ, Gale K. Substance P antagonists in substantia nigra are anticonvulsant. Brain Research. 382: 372-8. PMID 2428445 DOI: 10.1016/0006-8993(86)91347-8  1
1985 Gale K, Kerasidis H, Wrathall JR. Spinal cord contusion in the rat: behavioral analysis of functional neurologic impairment. Experimental Neurology. 88: 123-34. PMID 3979506 DOI: 10.1016/0014-4886(85)90118-9  1
1985 Garant DS, Gale K. Infusion of opiates into substantia nigra protects against maximal electroshock seizures in rats. The Journal of Pharmacology and Experimental Therapeutics. 234: 45-8. PMID 2989511  1
1984 Lim CR, Garant DS, Gale K. GABA agonist induced analgesia elicited from the lateral preoptic area in the rat. European Journal of Pharmacology. 107: 91-4. PMID 6098483 DOI: 10.1016/0014-2999(84)90095-5  1
1983 Gale K, Iadarola MJ, Casu M. Anticonvulsant action of GABAergic drugs: cellular and anatomical localization of their site of action in vivo. Progress in Clinical and Biological Research. 124: 39-62. PMID 6878396  1
1983 Garant DS, Gale K. Lesions of substantia nigra protect against experimentally induced seizures. Brain Research. 273: 156-61. PMID 6616222 DOI: 10.1016/0006-8993(83)91105-8  1
1982 Iadarola MJ, Gale K. Substantia nigra: site of anticonvulsant activity mediated by gamma-aminobutyric acid. Science (New York, N.Y.). 218: 1237-40. PMID 7146907  1
1981 Casu M, Gale K. Intracerebral injection of gamma vinyl GABA: method for measuring rates of GABA synthesis in specific brain regions in vivo. Life Sciences. 29: 681-8. PMID 7278507  0.44
1981 Iadarola MJ, Gale K. Cellular compartments of GABA in brain and their relationship to anticonvulsant activity. Molecular and Cellular Biochemistry. 39: 305-29. PMID 6273710  1
1981 Gale K, Casu M. Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications. Molecular and Cellular Biochemistry. 39: 369-405. PMID 6118827  0.44
1981 Casu M, Gale K. Differential effects of gamma-aminobutyric acid (GABA)-elevating agents on the neuroleptic-induced activation of striatal tyrosine-hydroxylase: evidence that di-n-propylacetate augments GABAergic neurotransmission. The Journal of Pharmacology and Experimental Therapeutics. 217: 177-80. PMID 6110774  0.44
1980 Shibuya H, Gale K, Pert CB. Supersensitivity to GABA's effect on benzodiazepine receptors develops after striatonigral lesions. European Journal of Pharmacology. 62: 243-4. PMID 7379846 DOI: 10.1016/0014-2999(80)90286-1  1
1980 Gale K, Iadarola MJ. Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition. Science (New York, N.Y.). 208: 288-91. PMID 6768130  1
1980 Gale K, Iadarola MJ. GABAergic denervation of rat substantia nigra: functional and pharmacological properties. Brain Research. 183: 217-23. PMID 6244049  1
1979 DiMicco JA, Gale K, Hamilton B, Gillis RA. GABA receptor control of parasympathetic outflow to heart: characterization and brainstem localization. Science (New York, N.Y.). 204: 1106-9. PMID 451556  1
1979 Iadarola MJ, Gale K. Dissociation between drug-induced increases in nerve terminal and non-nerve terminal pools of GABA in vivo. European Journal of Pharmacology. 59: 125-9. PMID 389641  1
1979 Iadarola MJ, Raines A, Gale K. Differential effects of n-dipropylacetate and amino-oxyacetic acid on gamma-aminobutyric acid levels in discrete areas of rat brain. Journal of Neurochemistry. 33: 1119-23. PMID 387917  1
1979 Guidotti A, Gale K, Suria A, Toffano G. Biochemical evidence for two classes of GABA receptors in rat brain. Brain Research. 172: 566-71. PMID 224975  1
1979 Gale K, Moroni F, Kumakura K, Guidotti A. Opiate-receptors in substantia nigra: role in the regulation of striatal tyrosine hydroxylase activity. Neuropharmacology. 18: 427-30. PMID 36574  1
1978 Guidotti A, Gale K, Toffano G, Vargas FM. Tolerance to tyrosine hydroxylase activation in n. accumbens and c. striatum after repeated injections of "classical" and "atypical" antischizophrenic drugs. Life Sciences. 23: 501-5. PMID 29190  1
1978 Gale K, Costa E, Toffano G, Hong JS, Guidotti A. Evidence for a role of nigral gamma-aminobutyric acid and substance P in the haloperidol-induced activation of striatal tyrosine hydroxylase. The Journal of Pharmacology and Experimental Therapeutics. 206: 29-37. PMID 26799  1
1977 Gale K, Hong JS, Ghidotti A. Presence of substance P and GABA in separate striatonigral neurons. Brain Research. 136: 371-5. PMID 922491  0.96
1977 Guidotti A, Gale K. Participation of GABA receptors in the short-term activation of striatal tyrosine-3-monooxygenase elicited by neuroleptics. Advances in Biochemical Psychopharmacology. 16: 455-60. PMID 18893  1
1977 Gale K, Guidotti A, Costa E. Dopamine-sensitive adenylate cyclase: location in substantia nigra. Science (New York, N.Y.). 195: 503-5. PMID 13499  1
1976 Gale KN, Guidotti A. GABA-mediated control of rat neostriatal tyrosine hydroxylase revealed by intranigral muscimol. Nature. 263: 691-3. PMID 10528  1
1975 Gale KN, Murray JP, Horita A. Modification of apomorphine induced stereotypies in rates by aversive conditioning. Proceedings of the Western Pharmacology Society. 18: 375-9. PMID 1237143  0.6
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