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Lorin S. Milescu, PhD - Publications

Affiliations: 
Biological Sciences University of Missouri - Columbia, Columbia, MO, United States 
Website:
http://milesculabs.biology.missouri.edu/index.html
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Strege PR, Cowan LM, Alcaino C, Mazzone A, Ahern CA, Milescu LS, Farrugia G, Beyder A. Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel. Elife. 12. PMID 36912788 DOI: 10.7554/eLife.79271  0.625
2022 Navarro MA, Amirshenava M, Salari A, Milescu M, Milescu LS. Parameter Optimization for Ion Channel Models: Integrating New Data with Known Channel Properties. Methods in Molecular Biology (Clifton, N.J.). 2385: 353-375. PMID 34888729 DOI: 10.1007/978-1-0716-1767-0_17  0.617
2020 Navarro MA, Salari A, Lin JL, Cowan LM, Penington NJ, Milescu M, Milescu LS. Sodium channels implement a molecular leaky integrator that detects action potentials and regulates neuronal firing. Elife. 9. PMID 32101161 DOI: 10.7554/Elife.54940  0.665
2020 Navarro MA, Salari A, Lin JL, Cowan LM, Penington NJ, Milescu M, Milescu LS. Author response: Sodium channels implement a molecular leaky integrator that detects action potentials and regulates neuronal firing Elife. DOI: 10.7554/Elife.54940.Sa2  0.642
2019 DeFazio RA, Navarro MA, Adams CE, Milescu LS, Moenter SM. Estradiol enhances the depolarizing response to GABA and AMPA synaptic conductances in arcuate kisspeptin neurons by diminishing voltage-gated potassium currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31628184 DOI: 10.1523/Jneurosci.0378-19.2019  0.611
2019 Adams CE, DeFazio RA, Christian CA, Milescu LS, Schnell S, Moenter SM. Changes in both neuron intrinsic properties and neurotransmission are needed to drive the increase in GnRH neuron firing rate during estradiol positive feedback. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30655354 DOI: 10.1523/Jneurosci.2880-18.2019  0.349
2019 Navarro MA, Lin J, Salari A, Milescu M, Milescu LS. Sodium Channels Implement a Molecular Leaky Integrator to Sense Spiking Frequency and Regulate Neuronal Firing Biophysical Journal. 116: 388a. DOI: 10.1016/J.Bpj.2018.11.2101  0.64
2018 Navarro MA, Milescu LS, Milescu M. Unlocking the gating mechanism of Kv2.1 using guangxitoxin. The Journal of General Physiology. PMID 30563879 DOI: 10.1085/Jgp.201812254  0.594
2018 Yamanishi T, Koizumi H, Navarro MA, Milescu LS, Smith JC. Kinetic properties of persistent Na current orchestrate oscillatory bursting in respiratory neurons. The Journal of General Physiology. PMID 30301870 DOI: 10.1085/Jgp.201812100  0.699
2018 Mishra A, Salari A, Berigan BR, Miguel KC, Amirshenava M, Robinson A, Zars BC, Lin JL, Milescu LS, Milescu M, Zars T. The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool. Scientific Reports. 8: 901. PMID 29343813 DOI: 10.1038/S41598-017-19065-4  0.735
2018 Salari A, Navarro MA, Milescu M, Milescu LS. Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints. The Journal of General Physiology. PMID 29321264 DOI: 10.1085/Jgp.201711911  0.655
2018 Navarro MA, Salari A, Milescu M, Milescu LS. Estimating kinetic mechanisms with prior knowledge II: Behavioral constraints and numerical tests. The Journal of General Physiology. PMID 29321263 DOI: 10.1085/Jgp.201711912  0.636
2018 Amirshenava M, Zars B, Berigan B, Martinez P, Zars T, Milescu LS, Milescu M. Drosophila-Inspired Molecular Thermosensors Biophysical Journal. 114: 640a. DOI: 10.1016/J.Bpj.2017.11.3456  0.699
2018 Navarro MA, Lin JL, Berigan BR, Milescu M, Milescu LS. Intracellular Calcium Alters Sodium Channel Kinetics to Influence Neuronal Firing Biophysical Journal. 114: 633a. DOI: 10.1016/J.Bpj.2017.11.3419  0.634
2017 Strege PR, Knutson K, Eggers SJ, Li JH, Wang F, Linden D, Szurszewski JH, Milescu L, Leiter AB, Farrugia G, Beyder A. Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release. Scientific Reports. 7: 15650. PMID 29142310 DOI: 10.1038/S41598-017-15834-3  0.608
2017 Salari A, Zars BC, Mishra A, Berigan B, Zars T, Milescu LS, Milescu M. Temperature Sensitivity of Drosophila Gustatory Receptor Gr28b Biophysical Journal. 112: 251a. DOI: 10.1016/J.Bpj.2016.11.1370  0.72
2017 Salari A, Elkins ZF, Navarro MA, Berigan BR, Lin JL, Milescu M, Milescu LS. Estimating Kinetic Mechanisms with Prior Knowledge Biophysical Journal. 112: 243a. DOI: 10.1016/J.Bpj.2016.11.1328  0.556
2016 Salari A, Vega BS, Milescu LS, Milescu M. Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels. Scientific Reports. 6: 23894. PMID 27045173 DOI: 10.1038/Srep23894  0.385
2016 Lombardo CB, Navarro MA, Salari A, Milescu LS. Modeling Ion Channel Kinetics with Parameter Constraints Biophysical Journal. 110: 438a. DOI: 10.1016/J.Bpj.2015.11.2361  0.688
2016 Miguel K, Salari A, Zars B, Zars T, Milescu LS, Milescu M. Temperature Sensitivity of Fruit Fly Gustatory Receptors Biophysical Journal. 110: 283a. DOI: 10.1016/J.Bpj.2015.11.1532  0.35
2016 Salari A, Navarro MA, Milescu LS. Modeling the kinetic mechanisms of voltage-gated ion channels Neuromethods. 113: 267-304. DOI: 10.1007/978-1-4939-3411-9_13  0.612
2015 Navarro MA, Hibbard JV, Miller ME, Nivin TW, Milescu LS. 3D Data Mapping and Real-Time Experiment Control and Visualization in Brain Slices. Biophysical Journal. 109: 1521-7. PMID 26488641 DOI: 10.1016/J.Bpj.2015.08.045  0.55
2015 Milescu LS. A stochastic relationship. Biophysical Journal. 108: 225-7. PMID 25606669 DOI: 10.1016/J.Bpj.2014.11.3475  0.439
2015 Navarro MA, Debs SL, Milescu LS. Coupling Compartmental Models to Live Neurons to Investigate Action Potential Mechanisms Biophysical Journal. 108: 577a. DOI: 10.1016/J.Bpj.2014.11.3153  0.644
2015 Hibbard JV, Navarro MA, Miller ME, Nivin TW, Milescu LS. Virtual Reality Environment for Patching and Imaging in Brain Slices Biophysical Journal. 108: 474a. DOI: 10.1016/J.Bpj.2014.11.2591  0.577
2011 Tabak J, Tomaiuolo M, Gonzalez-Iglesias AE, Milescu LS, Bertram R. Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16855-63. PMID 22090511 DOI: 10.1523/Jneurosci.3235-11.2011  0.381
2010 Milescu LS, Yamanishi T, Ptak K, Smith JC. Kinetic properties and functional dynamics of sodium channels during repetitive spiking in a slow pacemaker neuron. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12113-27. PMID 20826674 DOI: 10.1523/Jneurosci.0445-10.2010  0.572
2010 Milescu LS, Bean BP, Smith JC. Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7740-8. PMID 20519549 DOI: 10.1523/Jneurosci.6136-09.2010  0.668
2010 Nelson MT, Milescu LS, Todorovic SM, Scroggs RS. A modeling study of T-type Ca2+ channel gating and modulation by L-cysteine in rat nociceptors. Biophysical Journal. 98: 197-206. PMID 20338841 DOI: 10.1016/J.Bpj.2009.10.007  0.359
2010 Milescu LS. Fast Real-Time Computation of Na Channel Kinetic Models for Dynamic Clamp Biophysical Journal. 98: 112a. DOI: 10.1016/J.Bpj.2009.12.4202  0.467
2009 Ptak K, Yamanishi T, Aungst J, Milescu LS, Zhang R, Richerson GB, Smith JC. Raphé neurons stimulate respiratory circuit activity by multiple mechanisms via endogenously released serotonin and substance P. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3720-37. PMID 19321769 DOI: 10.1523/Jneurosci.5271-08.2009  0.475
2009 Bittner KC, Milescu L, Hanck DA. Kinetic Modeling of CaV3.1 Biophysical Journal. 96: 184a. DOI: 10.1016/J.Bpj.2008.12.861  0.416
2009 Milescu LS, Yamanishi T, Smith JC. A Kinetic Model That Explains Slow Inactivation Properties Of Na Channels In Pacemaker Neurons Biophysical Journal. 96: 251a. DOI: 10.1016/J.Bpj.2008.12.1237  0.56
2008 Milescu LS, Yamanishi T, Ptak K, Mogri MZ, Smith JC. Real-time kinetic modeling of voltage-gated ion channels using dynamic clamp. Biophysical Journal. 95: 66-87. PMID 18375511 DOI: 10.1529/biophysj.107.118190  0.543
2006 Milescu LS, Yildiz A, Selvin PR, Sachs F. Extracting dwell time sequences from processive molecular motor data. Biophysical Journal. 91: 3135-50. PMID 16905607 DOI: 10.1529/Biophysj.105.079517  0.609
2006 Milescu LS, Yildiz A, Selvin PR, Sachs F. Maximum likelihood estimation of molecular motor kinetics from staircase dwell-time sequences. Biophysical Journal. 91: 1156-68. PMID 16679362 DOI: 10.1529/Biophysj.105.079541  0.615
2005 Akk G, Milescu LS, Heckmann M. Activation of heteroliganded mouse muscle nicotinic receptors. The Journal of Physiology. 564: 359-76. PMID 15718267 DOI: 10.1113/Jphysiol.2004.078535  0.552
2005 Milescu LS, Akk G, Sachs F. Maximum likelihood estimation of ion channel kinetics from macroscopic currents. Biophysical Journal. 88: 2494-515. PMID 15681642 DOI: 10.1529/Biophysj.104.053256  0.727
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