Thuc Le, Ph.D. - Publications

Affiliations: 
Neuroscience University of California, Los Angeles, Los Angeles, CA 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yu K, Liu L, Li J, Ding W, Le TD. Multi-Source Causal Feature Selection. Ieee Transactions On Pattern Analysis and Machine Intelligence. PMID 30946660 DOI: 10.1109/TPAMI.2019.2908373  0.48
2019 Pham VV, Zhang J, Liu L, Truong B, Xu T, Nguyen TT, Li J, Le TD. Identifying miRNA-mRNA regulatory relationships in breast cancer with invariant causal prediction. Bmc Bioinformatics. 20: 143. PMID 30876399 DOI: 10.1186/s12859-019-2668-x  0.48
2018 Xu T, Su N, Liu L, Zhang J, Wang H, Zhang W, Gui J, Yu K, Li J, Le TD. miRBaseConverter: an R/Bioconductor package for converting and retrieving miRNA name, accession, sequence and family information in different versions of miRBase. Bmc Bioinformatics. 19: 514. PMID 30598108 DOI: 10.1186/s12859-018-2531-5  0.48
2018 Zhang W, Le TD, Liu L, Li J. Estimating heterogeneous treatment effect by balancing heterogeneity and fitness. Bmc Bioinformatics. 19: 518. PMID 30598067 DOI: 10.1186/s12859-018-2521-7  0.48
2018 Zhang J, Liu L, Li J, Le TD. LncmiRSRN: identification and analysis of long non-coding RNA related miRNA sponge regulatory network in human cancer. Bioinformatics (Oxford, England). PMID 29955818 DOI: 10.1093/bioinformatics/bty525  0.48
2018 Truong T, Suriyanarayanan T, Zeng G, Le TD, Liu L, Li J, Tong C, Wang Y, Seneviratne CJ. Use of Haploid Model of to Uncover Mechanism of Action of a Novel Antifungal Agent. Frontiers in Cellular and Infection Microbiology. 8: 164. PMID 29938200 DOI: 10.3389/fcimb.2018.00164  0.48
2018 Zhang J, Le TD, Liu L, Li J. Inferring and analyzing module-specific lncRNA-mRNA causal regulatory networks in human cancer. Briefings in Bioinformatics. PMID 29401217 DOI: 10.1093/bib/bby008  0.48
2017 Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, et al. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nature Communications. 8: 241. PMID 28808226 DOI: 10.1038/s41467-017-00221-3  0.4
2017 Zhang J, Le TD, Liu L, Li J. Inferring miRNA sponge co-regulation of protein-protein interactions in human breast cancer. Bmc Bioinformatics. 18: 243. PMID 28482794 DOI: 10.1186/s12859-017-1672-2  0.48
2017 Zhang J, Le TD, Liu L, Li J. Identifying miRNA sponge modules using biclustering and regulatory scores. Bmc Bioinformatics. 18: 44. PMID 28361682 DOI: 10.1186/s12859-017-1467-5  0.48
2016 Le T, Hoang T, Li J, Liu L, Liu H, Hu S. A fast PC algorithm for high dimensional causal discovery with multi-core PCs. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. PMID 27429444 DOI: 10.1109/TCBB.2016.2591526  0.48
2016 Le TD, Zhang J, Liu L, Li J. Computational methods for identifying miRNA sponge interactions. Briefings in Bioinformatics. PMID 27273287 DOI: 10.1093/bib/bbw042  0.48
2016 Zhang W, Le TD, Liu L, Zhou ZH, Li J. Predicting miRNA Targets by Integrating Gene Regulatory Knowledge with Expression Profiles. Plos One. 11: e0152860. PMID 27064982 DOI: 10.1371/journal.pone.0152860  0.48
2016 Kim W, Le TM, Wei L, Poddar S, Bazzy J, Wang X, Uong NT, Abt ER, Capri JR, Austin WR, Van Valkenburgh JS, Steele D, Gipson RM, Slavik R, Cabebe AE, et al. [18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035974 DOI: 10.1073/pnas.1524212113  0.4
2016 Xu T, Le TD, Liu L, Wang R, Sun B, Li J. Identifying Cancer Subtypes from miRNA-TF-mRNA Regulatory Networks and Expression Data. Plos One. 11: e0152792. PMID 27035433 DOI: 10.1371/journal.pone.0152792  0.48
2016 Masud Karim SM, Liu L, Le TD, Li J. Identification of miRNA-mRNA regulatory modules by exploring collective group relationships. Bmc Genomics. 17: 7. PMID 26817421 DOI: 10.1186/s12864-015-2300-z  0.48
2015 Le TD, Zhang J, Liu L, Liu H, Li J. miRLAB: An R Based Dry Lab for Exploring miRNA-mRNA Regulatory Relationships. Plos One. 10: e0145386. PMID 26716983 DOI: 10.1371/journal.pone.0145386  0.48
2015 Zhang J, Le TD, Liu L, He J, Li J. A novel framework for inferring condition-specific TF and miRNA co-regulation of protein-protein interactions. Gene. PMID 26611531 DOI: 10.1016/j.gene.2015.11.023  0.48
2015 Le TD, Zhang J, Liu L, Li J. Ensemble Methods for MiRNA Target Prediction from Expression Data. Plos One. 10: e0131627. PMID 26114448 DOI: 10.1371/journal.pone.0131627  0.48
2015 Feng J, Shao N, Szulwach KE, Vialou V, Huynh J, Zhong C, Le T, Ferguson D, Cahill ME, Li Y, Koo JW, Ribeiro E, Labonte B, Laitman BM, Estey D, et al. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature Neuroscience. 18: 536-44. PMID 25774451 DOI: 10.1038/nn.3976  0.48
2015 Le TD, Liu L, Zhang J, Liu B, Li J. From miRNA regulation to miRNA-TF co-regulation: computational approaches and challenges. Briefings in Bioinformatics. 16: 475-96. PMID 25016381 DOI: 10.1093/bib/bbu023  0.48
2014 Zhang J, Le TD, Liu L, Liu B, He J, Goodall GJ, Li J. Identifying direct miRNA-mRNA causal regulatory relationships in heterogeneous data. Journal of Biomedical Informatics. 52: 438-47. PMID 25181465 DOI: 10.1016/j.jbi.2014.08.005  0.48
2014 Calkins KL, Sanchez LA, Tseng CH, Faull KF, Yoon AJ, Ryan CM, Le T, Shew SB. Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates. Jpen. Journal of Parenteral and Enteral Nutrition. PMID 25139979 DOI: 10.1177/0148607114546375  0.4
2014 Zhang J, Le TD, Liu L, Liu B, He J, Goodall GJ, Li J. Inferring condition-specific miRNA activity from matched miRNA and mRNA expression data. Bioinformatics (Oxford, England). 30: 3070-7. PMID 25061069 DOI: 10.1093/bioinformatics/btu489  0.48
2014 Huang K, Wu Z, Liu Z, Hu G, Yu J, Chang KH, Kim KP, Le T, Faull KF, Rao N, Gennery A, Xue Z, Wang CY, Pellegrini M, Fan G. Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Human Molecular Genetics. 23: 6448-57. PMID 25027325 DOI: 10.1093/hmg/ddu365  0.48
2014 Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, Wang H, Le T, Faull KF, Chen R, Gu H, Bock C, Meissner A, Göttgens B, Darlington GJ, et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 14: 673-88. PMID 24792119 DOI: 10.1016/j.stem.2014.03.002  0.4
2014 Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G, Gao Q, Powell BE, Cheng AW, Faull KF, Lyko F, Jaenisch R. Loss of Tet enzymes compromises proper differentiation of embryonic stem cells. Developmental Cell. 29: 102-11. PMID 24735881 DOI: 10.1016/j.devcel.2014.03.003  0.48
2014 Nathanson DA, Armijo AL, Tom M, Li Z, Dimitrova E, Austin WR, Nomme J, Campbell DO, Ta L, Le TM, Lee JT, Darvish R, Gordin A, Wei L, Liao HI, et al. Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. The Journal of Experimental Medicine. 211: 473-86. PMID 24567448 DOI: 10.1084/jem.20131738  0.48
2014 Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B, Zhong C, Hu S, Le T, Fan G, Zhu H, Chang Q, Gao Y, Ming GL, Song H. Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nature Neuroscience. 17: 215-22. PMID 24362762 DOI: 10.1038/nn.3607  0.48
2013 Rudenko A, Dawlaty MM, Seo J, Cheng AW, Meng J, Le T, Faull KF, Jaenisch R, Tsai LH. Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron. 79: 1109-22. PMID 24050401 DOI: 10.1016/j.neuron.2013.08.003  0.48
2013 Le TD, Liu L, Liu B, Tsykin A, Goodall GJ, Satou K, Li J. Inferring microRNA and transcription factor regulatory networks in heterogeneous data. Bmc Bioinformatics. 14: 92. PMID 23497388 DOI: 10.1186/1471-2105-14-92  0.48
2013 Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT. Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 12: 470-8. PMID 23415914 DOI: 10.1016/j.stem.2013.01.016  0.48
2013 Le TD, Liu L, Tsykin A, Goodall GJ, Liu B, Sun BY, Li J. Inferring microRNA-mRNA causal regulatory relationships from expression data. Bioinformatics (Oxford, England). 29: 765-71. PMID 23365408 DOI: 10.1093/bioinformatics/btt048  0.48
2013 Dawlaty MM, Breiling A, Le T, Raddatz G, Barrasa MI, Cheng AW, Gao Q, Powell BE, Li Z, Xu M, Faull KF, Lyko F, Jaenisch R. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Developmental Cell. 24: 310-23. PMID 23352810 DOI: 10.1016/j.devcel.2012.12.015  0.48
2013 Moore LD, Le T, Fan G. DNA methylation and its basic function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 23-38. PMID 22781841 DOI: 10.1038/npp.2012.112  0.48
2012 Wu Z, Huang K, Yu J, Le T, Namihira M, Liu Y, Zhang J, Xue Z, Cheng L, Fan G. Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. Journal of Neuroscience Research. 90: 1883-91. PMID 22714992 DOI: 10.1002/jnr.23077  0.48
2011 Le T, Kim KP, Fan G, Faull KF. A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples. Analytical Biochemistry. 412: 203-9. PMID 21272560 DOI: 10.1016/j.ab.2011.01.026  0.48
2010 Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nature Neuroscience. 13: 423-30. PMID 20228804 DOI: 10.1038/nn.2514  0.48
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