Alcino J. Silva - Publications

University of California, Los Angeles, Los Angeles, CA 
Learning & memory

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Bickle J, De Sousa AF, Silva AJ. New research tools suggest a "levels-less" image of the behaving organism and dissolution of the reduction vs. anti-reduction dispute. Frontiers in Psychology. 13: 990316. PMID 36110269 DOI: 10.3389/fpsyg.2022.990316  0.758
2022 Chowdhury A, Luchetti A, Fernandes G, Filho DA, Kastellakis G, Tzilivaki A, Ramirez EM, Tran MY, Poirazi P, Silva AJ. A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking. Neuron. PMID 36041433 DOI: 10.1016/j.neuron.2022.08.001  0.841
2022 Shen Y, Zhou M, Cai D, Filho DA, Fernandes G, Cai Y, de Sousa AF, Tian M, Kim N, Lee J, Necula D, Zhou C, Li S, Salinas S, Liu A, ... ... Silva AJ, et al. CCR5 closes the temporal window for memory linking. Nature. PMID 35614219 DOI: 10.1038/s41586-022-04783-1  0.822
2022 Meenakshi PK, Mehrotra D, Nruthyathi N, Almeida-Filho D, Lee YS, Silva A, Balaji J. Novel measures of Morris water maze performance that use vector field maps to assess accuracy, uncertainty, and intention of navigational searches. Hippocampus. PMID 35025127 DOI: 10.1002/hipo.23404  0.517
2022 Shen Y, Luchetti A, Fernandes G, Do Heo W, Silva AJ. The emergence of molecular systems neuroscience. Molecular Brain. 15: 7. PMID 34983613 DOI: 10.1186/s13041-021-00885-5  0.776
2021 López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, ... ... Silva AJ, et al. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Science Advances. 7: eabf2073. PMID 34533985 DOI: 10.1126/sciadv.abf2073  0.671
2021 de Sousa AF, Chowdhury A, Silva AJ. Dimensions and mechanisms of memory organization. Neuron. PMID 34242564 DOI: 10.1016/j.neuron.2021.06.014  0.83
2020 Shuman T, Aharoni D, Cai DJ, Lee CR, Chavlis S, Page-Harley L, Vetere LM, Feng Y, Yang CY, Mollinedo-Gajate I, Chen L, Pennington ZT, Taxidis J, Flores SE, Cheng K, ... ... Silva AJ, et al. Breakdown of spatial coding and interneuron synchronization in epileptic mice. Nature Neuroscience. PMID 31907437 DOI: 10.1038/S41593-019-0559-0  0.767
2019 Yetton BD, Cai DJ, Spoormaker VI, Silva AJ, Mednick SC. Human Memories Can Be Linked by Temporal Proximity. Frontiers in Human Neuroscience. 13: 315. PMID 31572150 DOI: 10.3389/Fnhum.2019.00315  0.802
2019 Ryu HH, Kim T, Kim JW, Kang M, Park P, Kim YG, Kim H, Ha J, Choi JE, Lee J, Lim CS, Kim CH, Kim SJ, Silva AJ, Kaang BK, et al. Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory. Science Signaling. 12. PMID 30837304 DOI: 10.1126/scisignal.aau5755  0.816
2019 Joy MT, Ben Assayag E, Shabashov-Stone D, Liraz-Zaltsman S, Mazzitelli J, Arenas M, Abduljawad N, Kliper E, Korczyn AD, Thareja NS, Kesner EL, Zhou M, Huang S, Silva TK, Katz N, ... ... Silva AJ, et al. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 176: 1143-1157.e13. PMID 30794775 DOI: 10.1016/J.Cell.2019.01.044  0.704
2019 Silva A, Zhou M, Shen Y, Joy MT, Assayag EB, Shabashov-Stone D, Silva T, Kliper E, Liraz-Zaltsman S, Bornstein NM, Shohami E, Carmichael ST. Genetic manipulations of CCR5 and the multifaceted molecular cellular and circuit mechanisms of cognitive enhancement: A cautionary tale Ibro Reports. 6: S24. DOI: 10.1016/J.Ibror.2019.07.063  0.701
2018 Caracciolo L, Marosi M, Mazzitelli J, Latifi S, Sano Y, Galvan L, Kawaguchi R, Holley S, Levine MS, Coppola G, Portera-Cailliau C, Silva AJ, Carmichael ST. CREB controls cortical circuit plasticity and functional recovery after stroke. Nature Communications. 9: 2250. PMID 29884780 DOI: 10.1038/S41467-018-04445-9  0.492
2018 Liraz-Zaltsman S, Slusher B, Atrakchi-Baranes D, Rosenblatt K, Friedman Levi Y, Kesner EL, Silva AJ, Biegon A, Shohami E. Enhancement of brain D-serine mediates recovery of cognitive function after TBI. Journal of Neurotrauma. PMID 29648983 DOI: 10.1089/Neu.2017.5561  0.338
2018 Sehgal M, Zhou M, Lavi A, Huang S, Zhou Y, Silva AJ. Memory allocation mechanisms underlie memory linking across time. Neurobiology of Learning and Memory. PMID 29496645 DOI: 10.1016/J.Nlm.2018.02.021  0.787
2018 Lisman J, Cooper K, Sehgal M, Silva AJ. Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability. Nature Neuroscience. PMID 29434376 DOI: 10.1038/S41593-018-0076-6  0.495
2018 Frank AC, Huang S, Zhou M, Gdalyahu A, Kastellakis G, Silva TK, Lu E, Wen X, Poirazi P, Trachtenberg JT, Silva AJ. Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory. Nature Communications. 9: 422. PMID 29379017 DOI: 10.1038/S41467-017-02751-2  0.805
2017 Ibrahim AFA, Montojo CA, Haut KM, Karlsgodt KH, Hansen L, Congdon E, Rosser T, Bilder RM, Silva AJ, Bearden CE. Spatial working memory in neurofibromatosis 1: Altered neural activity and functional connectivity. Neuroimage. Clinical. 15: 801-811. PMID 28725547 DOI: 10.1016/j.nicl.2017.06.032  0.446
2017 Silva AJ. Memory's Intricate Web. Scientific American. 317: 30-37. PMID 28632232 DOI: 10.1038/scientificamerican0717-30  0.483
2017 Oh JY, Rhee S, Silva AJ, Lee YS, Kim HK. Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation. Neuroscience Letters. PMID 28366775 DOI: 10.1016/j.neulet.2017.03.036  0.534
2016 Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee YS, Fox K, Silva AJ. CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory. Elife. 5. PMID 27996938 DOI: 10.7554/Elife.20985  0.846
2016 Kastellakis G, Silva AJ, Poirazi P. Linking Memories across Time via Neuronal and Dendritic Overlaps in Model Neurons with Active Dendrites. Cell Reports. 17: 1491-1504. PMID 27806290 DOI: 10.1016/j.celrep.2016.10.015  0.517
2016 Rogerson T, Jayaprakash B, Cai DJ, Sano Y, Lee YS, Zhou Y, Bekal P, Deisseroth K, Silva AJ. Molecular and Cellular Mechanisms for Trapping and Activating Emotional Memories. Plos One. 11: e0161655. PMID 27579481 DOI: 10.1371/Journal.Pone.0161655  0.825
2016 Eichenbaum H, Amaral DG, Buffalo EA, Buzsáki G, Cohen N, Davachi L, Frank L, Heckers S, Morris RG, Moser EI, Nadel L, O'Keefe J, Preston A, Ranganath C, Silva A, et al. Hippocampus at 25. Hippocampus. PMID 27399159 DOI: 10.1002/hipo.22616  0.653
2016 Petrella LI, Cai Y, Sereno JV, Gonçalves SI, Silva AJ, Castelo-Branco M. Brain and behaviour phenotyping of a mouse model of neurofibromatosis type-1: an MRI/DTI study on social cognition. Genes, Brain, and Behavior. PMID 27283753 DOI: 10.1111/gbb.12305  0.356
2016 Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores SE, Kim I, Sano Y, Zhou M, Baumgaertel K, ... ... Silva AJ, et al. A shared neural ensemble links distinct contextual memories encoded close in time. Nature. 534: 115-8. PMID 27251287 DOI: 10.1038/Nature17955  0.836
2016 Bearden CE, Hellemann GS, Rosser T, Montojo C, Jonas R, Enrique N, Pacheco L, Hussain SA, Wu JY, Ho JS, McGough JJ, Sugar CA, Silva AJ. A randomized placebo-controlled lovastatin trial for neurobehavioral function in neurofibromatosis I. Annals of Clinical and Translational Neurology. 3: 266-79. PMID 27081657 DOI: 10.1002/Acn3.288  0.334
2016 Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee Y, Fox K, Silva AJ. Author response: CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory Elife. DOI: 10.7554/Elife.20985.030  0.836
2015 Tomson SN, Schreiner MJ, Narayan M, Rosser T, Enrique N, Silva AJ, Allen GI, Bookheimer SY, Bearden CE. Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1. Human Brain Mapping. 36: 4566-81. PMID 26304096 DOI: 10.1002/Hbm.22937  0.331
2015 Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Molecular Psychiatry. PMID 25917366 DOI: 10.1038/Mp.2015.48  0.779
2015 Korf B, Ahmadian R, Allanson J, Aoki Y, Bakker A, Wright EB, Denger B, Elgersma Y, Gelb BD, Gripp KW, Kerr B, Kontaridis M, Lazaro C, Linardic C, Lozano R, ... ... Silva AJ, et al. The third international meeting on genetic disorders in the RAS/MAPK pathway: Towards a therapeutic approach. American Journal of Medical Genetics. Part A. PMID 25900621 DOI: 10.1002/Ajmg.A.37089  0.544
2015 Kastellakis G, Cai DJ, Mednick SC, Silva AJ, Poirazi P. Synaptic clustering within dendrites: an emerging theory of memory formation. Progress in Neurobiology. 126: 19-35. PMID 25576663 DOI: 10.1016/J.Pneurobio.2014.12.002  0.798
2014 Sano Y, Shobe JL, Zhou M, Huang S, Shuman T, Cai DJ, Golshani P, Kamata M, Silva AJ. CREB regulates memory allocation in the insular cortex. Current Biology : Cb. 24: 2833-7. PMID 25454591 DOI: 10.1016/J.Cub.2014.10.018  0.839
2014 Lee YS, Ehninger D, Zhou M, Oh JY, Kang M, Kwak C, Ryu HH, Butz D, Araki T, Cai Y, Balaji J, Sano Y, Nam CI, Kim HK, Kaang BK, ... ... Silva AJ, et al. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nature Neuroscience. 17: 1736-43. PMID 25383899 DOI: 10.1038/Nn.3863  0.819
2014 Achterberg KG, Buitendijk GH, Kool MJ, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y. Temporal and region-specific requirements of αCaMKII in spatial and contextual learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11180-7. PMID 25143599 DOI: 10.1523/Jneurosci.0640-14.2014  0.808
2014 Czajkowski R, Jayaprakash B, Wiltgen B, Rogerson T, Guzman-Karlsson MC, Barth AL, Trachtenberg JT, Silva AJ. Encoding and storage of spatial information in the retrosplenial cortex. Proceedings of the National Academy of Sciences of the United States of America. 111: 8661-6. PMID 24912150 DOI: 10.1073/Pnas.1313222111  0.821
2014 Rogerson T, Cai DJ, Frank A, Sano Y, Shobe J, Lopez-Aranda MF, Silva AJ. Synaptic tagging during memory allocation. Nature Reviews. Neuroscience. 15: 157-69. PMID 24496410 DOI: 10.1038/Nrn3667  0.826
2013 Han X, Chen M, Wang F, Windrem M, Wang S, Shanz S, Xu Q, Oberheim NA, Bekar L, Betstadt S, Silva AJ, Takano T, Goldman SA, Nedergaard M. Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. Cell Stem Cell. 12: 342-53. PMID 23472873 DOI: 10.1016/j.stem.2012.12.015  0.402
2013 Zhou M, Li W, Huang S, Song J, Kim JY, Tian X, Kang E, Sano Y, Liu C, Balaji J, Wu S, Zhou Y, Zhou Y, Parivash SN, Ehninger D, ... ... Silva AJ, et al. mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons. Neuron. 77: 647-54. PMID 23439118 DOI: 10.1016/J.Neuron.2012.12.033  0.795
2013 Acosta MT, Bearden CE, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, Silva AJ. Corrigendum to "The Learning Disabilities Network (LeaDNet): Using Neurofibromatosis Type 1 [NF1] as a Paradigm for Translational Research" American Journal of Medical Genetics, Part A. 161: 236. DOI: 10.1002/Ajmg.A.35667  0.577
2012 Karlsgodt KH, Rosser T, Lutkenhoff ES, Cannon TD, Silva A, Bearden CE. Alterations in white matter microstructure in neurofibromatosis-1. Plos One. 7: e47854. PMID 23094098 DOI: 10.1371/journal.pone.0047854  0.473
2012 Gutmann DH, Parada LF, Silva AJ, Ratner N. Neurofibromatosis type 1: modeling CNS dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14087-93. PMID 23055477 DOI: 10.1523/Jneurosci.3242-12.2012  0.379
2012 Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, ... Silva AJ, et al. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American Journal of Medical Genetics. Part A. 158: 2225-32. PMID 22821737 DOI: 10.1002/Ajmg.A.35535  0.696
2012 Gdalyahu A, Tring E, Polack PO, Gruver R, Golshani P, Fanselow MS, Silva AJ, Trachtenberg JT. Associative fear learning enhances sparse network coding in primary sensory cortex. Neuron. 75: 121-32. PMID 22794266 DOI: 10.1016/J.Neuron.2012.04.035  0.567
2012 Wefers B, Hitz C, Hölter SM, Trümbach D, Hansen J, Weber P, Pütz B, Deussing JM, de Angelis MH, Roenneberg T, Zheng F, Alzheimer C, Silva A, Wurst W, Kühn R. MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults. Plos One. 7: e35035. PMID 22529971 DOI: 10.1371/Journal.Pone.0035035  0.353
2012 Cho J, Bhatt R, Elgersma Y, Silva AJ. α-Calcium calmodulin kinase II modulates the temporal structure of hippocampal bursting patterns. Plos One. 7: e31649. PMID 22363696 DOI: 10.1371/Journal.Pone.0031649  0.764
2012 Halt AR, Dallapiazza RF, Zhou Y, Stein IS, Qian H, Juntti S, Wojcik S, Brose N, Silva AJ, Hell JW. CaMKII binding to GluN2B is critical during memory consolidation. The Embo Journal. 31: 1203-16. PMID 22234183 DOI: 10.1038/Emboj.2011.482  0.483
2012 Ehninger D, Sano Y, de Vries PJ, Dies K, Franz D, Geschwind DH, Kaur M, Lee YS, Li W, Lowe JK, Nakagawa JA, Sahin M, Smith K, Whittemore V, Silva AJ. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice. Molecular Psychiatry. 17: 62-70. PMID 21079609 DOI: 10.1038/Mp.2010.115  0.751
2012 Ehninger D, Sano Y, De Vries PJ, Dies K, Franz D, Geschwind DH, Kaur M, Lee YS, Li W, Lowe JK, Nakagawa JA, Sahin M, Smith K, Whittemore V, Silva AJ. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice (Molecular Psychiatry (2012) 17, (62-70) DOI:10.1038/mp.2010.115) Molecular Psychiatry. 17: 469-470. DOI: 10.1038/Mp.2011.39  0.731
2011 Kye MJ, Neveu P, Lee YS, Zhou M, Steen JA, Sahin M, Kosik KS, Silva AJ. NMDA mediated contextual conditioning changes miRNA expression. Plos One. 6: e24682. PMID 21931811 DOI: 10.1371/Journal.Pone.0024682  0.741
2011 Lee YS, Silva AJ. Modeling hyperactivity: of mice and men. Nature Medicine. 17: 541-2. PMID 21546967 DOI: 10.1038/nm0511-541  0.506
2011 Ehninger D, Silva AJ. Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders. Trends in Molecular Medicine. 17: 78-87. PMID 21115397 DOI: 10.1016/j.molmed.2010.10.002  0.604
2011 Ehninger D, Silva AJ. Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis. Behavior Genetics. 41: 357-63. PMID 20882401 DOI: 10.1007/s10519-010-9398-1  0.614
2010 Kaneko M, Cheetham CE, Lee YS, Silva AJ, Stryker MP, Fox K. Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 107: 19026-31. PMID 20937865 DOI: 10.1073/Pnas.1013866107  0.502
2010 Wiltgen BJ, Zhou M, Cai Y, Balaji J, Karlsson MG, Parivash SN, Li W, Silva AJ. The hippocampus plays a selective role in the retrieval of detailed contextual memories. Current Biology : Cb. 20: 1336-44. PMID 20637623 DOI: 10.1016/J.Cub.2010.06.068  0.842
2010 Shilyansky C, Karlsgodt KH, Cummings DM, Sidiropoulou K, Hardt M, James AS, Ehninger D, Bearden CE, Poirazi P, Jentsch JD, Cannon TD, Levine MS, Silva AJ. Neurofibromin regulates corticostriatal inhibitory networks during working memory performance. Proceedings of the National Academy of Sciences of the United States of America. 107: 13141-6. PMID 20624961 DOI: 10.1073/Pnas.1004829107  0.834
2010 Buard I, Coultrap SJ, Freund RK, Lee YS, Dell'Acqua ML, Silva AJ, Bayer KU. CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8214-20. PMID 20554872 DOI: 10.1523/Jneurosci.1469-10.2010  0.641
2010 Matynia A, Ng CH, Dansithong W, Chiang A, Silva AJ, Reddy S. Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy. Plos One. 5: e9857. PMID 20360842 DOI: 10.1371/Journal.Pone.0009857  0.688
2010 Shilyansky C, Lee YS, Silva AJ. Molecular and cellular mechanisms of learning disabilities: a focus on NF1. Annual Review of Neuroscience. 33: 221-43. PMID 20345245 DOI: 10.1146/Annurev-Neuro-060909-153215  0.802
2010 Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nature Neuroscience. 13: 423-30. PMID 20228804 DOI: 10.1038/Nn.2514  0.42
2010 Zhao Y, Fung C, Shin D, Shin BC, Thamotharan S, Sankar R, Ehninger D, Silva A, Devaskar SU. Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. Molecular Psychiatry. 15: 286-99. PMID 19506559 DOI: 10.1038/Mp.2009.51  0.649
2009 Silva AJ, Zhou Y, Rogerson T, Shobe J, Balaji J. Molecular and cellular approaches to memory allocation in neural circuits. Science (New York, N.Y.). 326: 391-5. PMID 19833959 DOI: 10.1126/Science.1174519  0.839
2009 Silva AJ, Ehninger D. Adult reversal of cognitive phenotypes in neurodevelopmental disorders. Journal of Neurodevelopmental Disorders. 1: 150-7. PMID 19812701 DOI: 10.1007/s11689-009-9018-7  0.611
2009 Zhou Y, Won J, Karlsson MG, Zhou M, Rogerson T, Balaji J, Neve R, Poirazi P, Silva AJ. CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala. Nature Neuroscience. 12: 1438-43. PMID 19783993 DOI: 10.1038/Nn.2405  0.821
2009 Ehninger D, de Vries PJ, Silva AJ. From mTOR to cognition: molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis. Journal of Intellectual Disability Research : Jidr. 53: 838-51. PMID 19694899 DOI: 10.1111/j.1365-2788.2009.01208.x  0.621
2009 Ehninger D, Silva AJ. Genetics and neuropsychiatric disorders: treatment during adulthood. Nature Medicine. 15: 849-50. PMID 19661989 DOI: 10.1038/nm0809-849  0.59
2009 Huynh DP, Maalouf M, Silva AJ, Schweizer FE, Pulst SM. Dissociated fear and spatial learning in mice with deficiency of ataxin-2. Plos One. 4: e6235. PMID 19617910 DOI: 10.1371/Journal.Pone.0006235  0.385
2009 Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Human Molecular Genetics. 18: 2875-88. PMID 19433415 DOI: 10.1093/Hmg/Ddp222  0.699
2009 Lee YS, Silva AJ. The molecular and cellular biology of enhanced cognition. Nature Reviews. Neuroscience. 10: 126-40. PMID 19153576 DOI: 10.1038/nrn2572  0.579
2008 Ehninger D, Li W, Fox K, Stryker MP, Silva AJ. Reversing neurodevelopmental disorders in adults. Neuron. 60: 950-60. PMID 19109903 DOI: 10.1016/J.Neuron.2008.12.007  0.658
2008 Kimura R, Silva AJ, Ohno M. Autophosphorylation of alphaCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 837-43. PMID 18984565 DOI: 10.1101/lm.1049608  0.495
2008 Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, Parada LF, Mody I, Silva AJ. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 135: 549-60. PMID 18984165 DOI: 10.1016/J.Cell.2008.09.060  0.794
2008 Wayman GA, Lee YS, Tokumitsu H, Silva AJ, Silva A, Soderling TR. Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron. 59: 914-31. PMID 18817731 DOI: 10.1016/j.neuron.2008.08.021  0.574
2008 Krab LC, de Goede-Bolder A, Aarsen FK, Pluijm SM, Bouman MJ, van der Geest JN, Lequin M, Catsman CE, Arts WF, Kushner SA, Silva AJ, de Zeeuw CI, Moll HA, Elgersma Y. Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial. Jama. 300: 287-94. PMID 18632543 DOI: 10.1001/Jama.300.3.287  0.764
2008 Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nature Medicine. 14: 843-8. PMID 18568033 DOI: 10.1038/Nm1788  0.83
2008 Matynia A, Anagnostaras SG, Wiltgen BJ, Lacuesta M, Fanselow MS, Silva AJ. A high through-put reverse genetic screen identifies two genes involved in remote memory in mice. Plos One. 3: e2121. PMID 18464936 DOI: 10.1371/Journal.Pone.0002121  0.824
2008 Won J, Silva AJ. Molecular and cellular mechanisms of memory allocation in neuronetworks. Neurobiology of Learning and Memory. 89: 285-92. PMID 17962049 DOI: 10.1016/j.nlm.2007.08.017  0.511
2008 Silva A. Molecular and cellular cognition: unraveling mechanisms and finding cures for learning disabilities International Journal of Developmental Neuroscience. 26: 830. DOI: 10.1016/J.Ijdevneu.2008.09.019  0.341
2007 Zhou Y, Takahashi E, Li W, Halt A, Wiltgen B, Ehninger D, Li GD, Hell JW, Kennedy MB, Silva AJ. Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13843-53. PMID 18077696 DOI: 10.1523/Jneurosci.4486-07.2007  0.803
2007 Li W, Zhou Y, Jentsch JD, Brown RA, Tian X, Ehninger D, Hennah W, Peltonen L, Lönnqvist J, Huttunen MO, Kaprio J, Trachtenberg JT, Silva AJ, Cannon TD. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 18280-5. PMID 17984054 DOI: 10.1073/pnas.0706900104  0.757
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, ... Silva AJ, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024  0.56
2007 Hojjati MR, van Woerden GM, Tyler WJ, Giese KP, Silva AJ, Pozzo-Miller L, Elgersma Y. Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nature Neuroscience. 10: 1125-7. PMID 17660813 DOI: 10.1038/Nn1946  0.782
2007 Wiltgen BJ, Silva AJ. Memory for context becomes less specific with time. Learning & Memory (Cold Spring Harbor, N.Y.). 14: 313-7. PMID 17522020 DOI: 10.1101/Lm.430907  0.752
2007 Han JH, Kushner SA, Yiu AP, Cole CJ, Matynia A, Brown RA, Neve RL, Guzowski JF, Silva AJ, Josselyn SA. Neuronal competition and selection during memory formation. Science (New York, N.Y.). 316: 457-60. PMID 17446403 DOI: 10.1126/Science.1139438  0.822
2007 Silva AJ. Molecular and cellular cognition: Unraveling mechanisms of learning and memory Neuroscience Research. 58: S18. DOI: 10.1016/j.neures.2007.06.106  0.478
2006 Murphy GG, Shah V, Hell JW, Silva AJ. Investigation of age-related cognitive decline using mice as a model system: neurophysiological correlates. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 14: 1012-21. PMID 17138808 DOI: 10.1097/01.JGP.0000209404.54310.b3  0.65
2006 Murphy GG, Rahnama NP, Silva AJ. Investigation of age-related cognitive decline using mice as a model system: behavioral correlates. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 14: 1004-11. PMID 17138807 DOI: 10.1097/01.JGP.0000209405.27548.7b  0.638
2006 Frankland PW, Ding HK, Takahashi E, Suzuki A, Kida S, Silva AJ. Stability of recent and remote contextual fear memory. Learning & Memory (Cold Spring Harbor, N.Y.). 13: 451-7. PMID 16882861 DOI: 10.1101/Lm.183406  0.826
2006 Ohno M, Sametsky EA, Silva AJ, Disterhoft JF. Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability. The European Journal of Neuroscience. 23: 2235-40. PMID 16630070 DOI: 10.1111/j.1460-9568.2006.04746.x  0.433
2006 Acosta MT, Gioia GA, Silva AJ. Neurofibromatosis type 1: new insights into neurocognitive issues. Current Neurology and Neuroscience Reports. 6: 136-43. PMID 16522267 DOI: 10.1007/s11910-996-0036-5  0.317
2006 Nagy V, Bozdagi O, Matynia A, Balcerzyk M, Okulski P, Dzwonek J, Costa RM, Silva AJ, Kaczmarek L, Huntley GW. Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1923-34. PMID 16481424 DOI: 10.1523/Jneurosci.4359-05.2006  0.755
2006 Uchida S, Sakai S, Furuichi T, Hosoda H, Toyota K, Ishii T, Kitamoto A, Sekine M, Koike K, Masushige S, Murphy G, Silva AJ, Kida S. Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain. Genes, Brain, and Behavior. 5: 96-106. PMID 16436193 DOI: 10.1111/J.1601-183X.2005.00139.X  0.745
2006 Chen AP, Ohno M, Giese KP, Kühn R, Chen RL, Silva AJ. Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory. Journal of Neuroscience Research. 83: 28-38. PMID 16342120 DOI: 10.1002/jnr.20703  0.414
2005 Li W, Cui Y, Kushner SA, Brown RA, Jentsch JD, Frankland PW, Cannon TD, Silva AJ. The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Current Biology : Cb. 15: 1961-7. PMID 16271875 DOI: 10.1016/J.Cub.2005.09.043  0.823
2005 Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9721-34. PMID 16237176 DOI: 10.1523/Jneurosci.2836-05.2005  0.809
2005 Costa RM, Drew C, Silva AJ. Notch to remember. Trends in Neurosciences. 28: 429-35. PMID 15922461 DOI: 10.1016/j.tins.2005.05.003  0.633
2005 Ohno M, Tseng W, Silva AJ, Disterhoft JF. Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of alphaCaMKII in mice. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 211-5. PMID 15897256 DOI: 10.1101/lm.90205  0.418
2005 Ehninger D, Matynia A, Silva AJ. Trafficking in emotions. Nature Neuroscience. 8: 548-50. PMID 15856058 DOI: 10.1038/Nn0505-548  0.744
2005 Josselyn SA, Mortezavi M, Silva AJ. CREB: A cornerstone of memory consolidation? Synaptic Plasticity and Transsynaptic Signaling. 359-380. DOI: 10.1007/0-387-25443-9_21  0.658
2004 Murphy GG, Fedorov NB, Giese KP, Ohno M, Friedman E, Chen R, Silva AJ. Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice. Current Biology : Cb. 14: 1907-15. PMID 15530391 DOI: 10.1016/j.cub.2004.10.021  0.672
2004 Wiltgen BJ, Brown RA, Talton LE, Silva AJ. New circuits for old memories: the role of the neocortex in consolidation. Neuron. 44: 101-8. PMID 15450163 DOI: 10.1016/J.Neuron.2004.09.015  0.81
2004 Israely I, Costa RM, Xie CW, Silva AJ, Kosik KS, Liu X. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Current Biology : Cb. 14: 1657-63. PMID 15380068 DOI: 10.1016/J.Cub.2004.08.065  0.586
2004 Josselyn SA, Kida S, Silva AJ. Inducible repression of CREB function disrupts amygdala-dependent memory. Neurobiology of Learning and Memory. 82: 159-63. PMID 15341801 DOI: 10.1016/J.Nlm.2004.05.008  0.76
2004 Frankland PW, Josselyn SA, Anagnostaras SG, Kogan JH, Takahashi E, Silva AJ. Consolidation of CS and US representations in associative fear conditioning. Hippocampus. 14: 557-69. PMID 15301434 DOI: 10.1002/Hipo.10208  0.824
2004 Suzuki A, Josselyn SA, Frankland PW, Masushige S, Silva AJ, Kida S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4787-95. PMID 15152039 DOI: 10.1523/Jneurosci.5491-03.2004  0.839
2004 Frankland PW, Bontempi B, Talton LE, Kaczmarek L, Silva AJ. The involvement of the anterior cingulate cortex in remote contextual fear memory. Science (New York, N.Y.). 304: 881-3. PMID 15131309 DOI: 10.1126/science.1094804  0.752
2004 Brown R, Silva AJ. Molecular and cellular cognition; the unraveling of memory retrieval. Cell. 117: 3-4. PMID 15066276 DOI: 10.1016/S0092-8674(04)00295-8  0.592
2004 Frankland PW, Wang Y, Rosner B, Shimizu T, Balleine BW, Dykens EM, Ornitz EM, Silva AJ. Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice. Molecular Psychiatry. 9: 417-25. PMID 14981523 DOI: 10.1038/Sj.Mp.4001432  0.705
2003 Wang J, Ren K, Pérez J, Silva AJ, Peña de Ortiz S. The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 503-9. PMID 14657261 DOI: 10.1101/lm.63003  0.454
2003 Costa RM, Honjo T, Silva AJ. Learning and memory deficits in Notch mutant mice. Current Biology : Cb. 13: 1348-54. PMID 12906797 DOI: 10.1016/S0960-9822(03)00492-5  0.695
2003 Bozon B, Kelly A, Josselyn SA, Silva AJ, Davis S, Laroche S. MAPK, CREB and zif268 are all required for the consolidation of recognition memory. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 805-14. PMID 12740127 DOI: 10.1098/Rstb.2002.1224  0.72
2003 Frankland PW, Ohno M, Takahashi E, Chen AR, Costa RM, Kushner SA, Silva AJ. Pharmacologically regulated induction of silent mutations (PRISM): combined pharmacological and genetic approaches for learning and memory. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 9: 104-9. PMID 12708614 DOI: 10.1177/1073858403252225  0.812
2003 Weeber EJ, Jiang YH, Elgersma Y, Varga AW, Carrasquillo Y, Brown SE, Christian JM, Mirnikjoo B, Silva A, Beaudet AL, Sweatt JD. Derangements of hippocampal calcium/calmodulin-dependent protein kinase II in a mouse model for Angelman mental retardation syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2634-44. PMID 12684449 DOI: 10.1523/Jneurosci.23-07-02634.2003  0.638
2003 Dhaka A, Costa RM, Hu H, Irvin DK, Patel A, Kornblum HI, Silva AJ, O'Dell TJ, Colicelli J. The RAS effector RIN1 modulates the formation of aversive memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 748-57. PMID 12574403 DOI: 10.1523/Jneurosci.23-03-00748.2003  0.621
2003 Costa RM, Silva AJ. Mouse models of neurofibromatosis type I: bridging the GAP. Trends in Molecular Medicine. 9: 19-23. PMID 12524206 DOI: 10.1016/S1471-4914(02)00008-4  0.562
2003 Silva AJ. Molecular and cellular cognitive studies of the role of synaptic plasticity in memory. Journal of Neurobiology. 54: 224-37. PMID 12486706 DOI: 10.1002/neu.10169  0.489
2003 Anagnostaras SG, Murphy GG, Hamilton SE, Mitchell SL, Rahnama NP, Nathanson NM, Silva AJ. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nature Neuroscience. 6: 51-8. PMID 12483218 DOI: 10.1038/nn992  0.825
2002 Matynia A, Kushner SA, Silva AJ. Genetic approaches to molecular and cellular cognition: a focus on LTP and learning and memory. Annual Review of Genetics. 36: 687-720. PMID 12429705 DOI: 10.1146/Annurev.Genet.36.062802.091007  0.788
2002 Elgersma Y, Fedorov NB, Ikonen S, Choi ES, Elgersma M, Carvalho OM, Giese KP, Silva AJ. Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning. Neuron. 36: 493-505. PMID 12408851 DOI: 10.1016/S0896-6273(02)01007-3  0.625
2002 Taha S, Hanover JL, Silva AJ, Stryker MP. Autophosphorylation of alphaCaMKII is required for ocular dominance plasticity. Neuron. 36: 483-91. PMID 12408850 DOI: 10.1016/S0896-6273(02)00966-2  0.346
2002 Costa RM, Silva AJ. Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1. Journal of Child Neurology. 17: 622-6; discussion 62. PMID 12403561 DOI: 10.1177/088307380201700813  0.604
2002 Silva AJ, Josselyn SA. The molecules of forgetfulness. Nature. 418: 929-30. PMID 12198533 DOI: 10.1038/418929A  0.591
2002 Ohno M, Frankland PW, Silva AJ. A pharmacogenetic inducible approach to the study of NMDA/alphaCaMKII signaling in synaptic plasticity. Current Biology : Cb. 12: 654-6. PMID 11967152 DOI: 10.1016/S0960-9822(02)00767-4  0.668
2002 Kida S, Josselyn SA, Peña de Ortiz S, Kogan JH, Chevere I, Masushige S, Silva AJ. CREB required for the stability of new and reactivated fear memories. Nature Neuroscience. 5: 348-55. PMID 11889468 DOI: 10.1038/Nn819  0.759
2002 Givogri MI, Costa RM, Schonmann V, Silva AJ, Campagnoni AT, Bongarzone ER. Central nervous system myelination in mice with deficient expression of Notch1 receptor. Journal of Neuroscience Research. 67: 309-20. PMID 11813235 DOI: 10.1002/Jnr.10128  0.521
2002 Costa RM, Federov NB, Kogan JH, Murphy GG, Stern J, Ohno M, Kucherlapati R, Jacks T, Silva AJ. Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature. 415: 526-30. PMID 11793011 DOI: 10.1038/Nature711  0.736
2002 Silva AJ. The four Cs of memory Nature Neuroscience. 5: 1259-1259. DOI: 10.1038/nn1202-1259  0.467
2002 Silva AJ, Frankland PW, Marowitz Z, Friedman E, Lazlo G, Cioffi D, Jacks T, Bourtchuladze R. Erratum: A mouse model for the learning and memory deficits associated with neurofibromatosis type I Nature Genetics. 31: 439-439. DOI: 10.1038/ng0802-439a  0.652
2002 Josselyn SA, Kida S, de Ortiz SP, Silva AJ. Chapter XIII CREB, plasticity and memory Handbook of Chemical Neuroanatomy. 19: 329-361. DOI: 10.1016/S0924-8196(02)80024-0  0.736
2001 Matynia A, Anagnostaras SG, Silva AJ. Weaving the molecular and cognitive strands of memory. Neuron. 32: 557-9. PMID 11719197 DOI: 10.1016/S0896-6273(01)00510-4  0.82
2001 Ohno M, Frankland PW, Chen AP, Costa RM, Silva AJ. Inducible, pharmacogenetic approaches to the study of learning and memory. Nature Neuroscience. 4: 1238-43. PMID 11713472 DOI: 10.1038/nn771  0.703
2001 Giese KP, Friedman E, Telliez JB, Fedorov NB, Wines M, Feig LA, Silva AJ. Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1). Neuropharmacology. 41: 791-800. PMID 11640934 DOI: 10.1016/S0028-3908(01)00096-X  0.425
2001 Hamilton SE, Hardouin SN, Anagnostaras SG, Murphy GG, Richmond KN, Silva AJ, Feigl EO, Nathanson NM. Alteration of cardiovascular and neuronal function in M1 knockout mice. Life Sciences. 68: 2489-93. PMID 11392617 DOI: 10.1016/S0024-3205(01)01043-8  0.812
2001 Frankland PW, O'Brien C, Ohno M, Kirkwood A, Silva AJ. Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory. Nature. 411: 309-13. PMID 11357133 DOI: 10.1038/35077089  0.686
2001 Costa RM, Yang T, Huynh DP, Pulst SM, Viskochil DH, Silva AJ, Brannan CI. Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1. Nature Genetics. 27: 399-405. PMID 11279521 DOI: 10.1038/86898  0.616
2001 Silva AJ, Elgersma Y, Costa RM. From genes to therapies: The role of animal models Clinical Neuroscience Research. 1: 187-193. DOI: 10.1016/S1566-2772(01)00005-6  0.68
2000 Falls WA, Kogan JH, Silva AJ, Willott JF, Carlson S, Turner JG. Fear-potentiated startle, but not prepulse inhibition of startle, is impaired in CREBalphadelta-/- mutant mice. Behavioral Neuroscience. 114: 998-1004. PMID 11085615 DOI: 10.1037//0735-7044.114.5.998  0.381
2000 Glazewski S, Giese KP, Silva A, Fox K. The role of alpha-CaMKII autophosphorylation in neocortical experience-dependent plasticity. Nature Neuroscience. 3: 911-918. PMID 10966622 DOI: 10.1038/78820  0.336
2000 Pandey SC, Mittal N, Silva AJ. Blockade of cyclic AMP-responsive element DNA binding in the brain of CREB delta/alpha mutant mice. Neuroreport. 11: 2577-80. PMID 10943725 DOI: 10.1097/00001756-200008030-00045  0.311
2000 Ferguson GD, Anagnostaras SG, Silva AJ, Herschman HR. Deficits in memory and motor performance in synaptotagmin IV mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 5598-603. PMID 10792055 DOI: 10.1073/Pnas.100104597  0.828
2000 Anagnostaras SG, Josselyn SA, Frankland PW, Silva AJ. Computer-assisted behavioral assessment of Pavlovian fear conditioning in mice. Learning & Memory (Cold Spring Harbor, N.Y.). 7: 58-72. PMID 10706603 DOI: 10.1101/Lm.7.1.58  0.795
2000 Kogan JH, Frankland PW, Silva AJ. Long-term memory underlying hippocampus-dependent social recognition in mice. Hippocampus. 10: 47-56. PMID 10706216 DOI: 10.1002/(SICI)1098-1063(2000)10:1<47::AID-HIPO5>3.0.CO;2-6  0.645
2000 Silva AJ, Elgersma Y, Costa RM. Molecular and cellular mechanisms of cognitive function: implications for psychiatric disorders. Biological Psychiatry. 47: 200-9. PMID 10682217 DOI: 10.1016/S0006-3223(99)00294-2  0.777
1999 Silva AJ, Murphy GG. cAMP and memory: a seminal lesson from Drosophila and Aplysia. Brain Research Bulletin. 50: 441-2. PMID 10643474 DOI: 10.1016/S0361-9230(99)00124-0  0.73
1999 Glazewski S, Barth AL, Wallace H, McKenna M, Silva A, Fox K. Impaired experience-dependent plasticity in barrel cortex of mice lacking the alpha and delta isoforms of CREB. Cerebral Cortex (New York, N.Y. : 1991). 9: 249-56. PMID 10355905 DOI: 10.1093/Cercor/9.3.249  0.342
1999 Elgersma Y, Silva AJ. Molecular mechanisms of synaptic plasticity and memory. Current Opinion in Neurobiology. 9: 209-13. PMID 10322188 DOI: 10.1016/S0959-4388(99)80029-4  0.69
1999 Narisawa-Saito M, Silva AJ, Yamaguchi T, Hayashi T, Yamamoto T, Nawa H. Growth factor-mediated Fyn signaling regulates alpha-amino-3- hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor expression in rodent neocortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 96: 2461-6. PMID 10051665 DOI: 10.1073/Pnas.96.5.2461  0.328
1998 Cho YH, Friedman E, Silva AJ. Ibotenate lesions of the hippocampus impair spatial learning but not contextual fear conditioning in mice Behavioural Brain Research. 98: 77-87. PMID 10210524 DOI: 10.1016/S0166-4328(98)00054-0  0.416
1998 Silva AJ, Elgersma Y, Friedman E, Stern J, Kogan J. A mouse model for learning and memory defects associated with neurofibromatosis type I. Pathologie-Biologie. 46: 697-8. PMID 9885821  0.647
1998 Silva AJ, Giese KP, Fedorov NB, Frankland PW, Kogan JH. Molecular, cellular, and neuroanatomical substrates of place learning. Neurobiology of Learning and Memory. 70: 44-61. PMID 9753586 DOI: 10.1006/nlme.1998.3837  0.633
1998 Frankland PW, Cestari V, Filipkowski RK, McDonald RJ, Silva AJ. The dorsal hippocampus is essential for context discrimination but not for contextual conditioning. Behavioral Neuroscience. 112: 863-74. PMID 9733192 DOI: 10.1037//0735-7044.112.4.863  0.759
1998 Silva AJ, Kogan JH, Frankland PW, Kida S. CREB and memory. Annual Review of Neuroscience. 21: 127-48. PMID 9530494 DOI: 10.1146/Annurev.Neuro.21.1.127  0.752
1998 Giese KP, Fedorov NB, Filipkowski RK, Silva AJ. Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science (New York, N.Y.). 279: 870-3. PMID 9452388 DOI: 10.1126/science.279.5352.870  0.704
1998 Cho YH, Giese KP, Tanila H, Silva AJ, Eichenbaum H. Abnormal hippocampal spatial representations in alphaCaMKIIT286A and CREBalphaDelta- mice. Science (New York, N.Y.). 279: 867-9. PMID 9452387 DOI: 10.1126/science.279.5352.867  0.382
1998 Silva AJ, Giese KP. Gene targeting: a novel window into the biology of learning and memory Neurobiology of Learning and Memory. 89-142. DOI: 10.1016/B978-012475655-7/50004-6  0.483
1998 Silva AJ, Mayford M. Learning and memory: Editorial Learning and Memory. 5: fmvii.  0.713
1997 Silva AJ, Smith AM, Giese KP. Gene targeting and the biology of learning and memory Annual Review of Genetics. 31: 527-46. PMID 9442906 DOI: 10.1146/annurev.genet.31.1.527  0.493
1997 Silva AJ, Simpson EM, Takahashi JS, Lipp HP, Nakanishi S, Wehner JM, Giese KP, Tully T, Abel T, Chapman PF, Fox K, Grant S, Itohara S, Lathe R, Mayford M, et al. Mutant mice and neuroscience: Recommendations concerning genetic background Neuron. 19: 755-759. PMID 9354323 DOI: 10.1016/S0896-6273(00)80958-7  0.689
1997 Crawley JN, Belknap JK, Collins A, Crabbe JC, Frankel W, Henderson N, Hitzemann RJ, Maxson SC, Miner LL, Silva AJ, Wehner JM, Wynshaw-Boris A, Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology. 132: 107-24. PMID 9266608 DOI: 10.1007/S002130050327  0.307
1997 Kirkwood A, Silva A, Bear MF. Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 3380-3. PMID 9096402 DOI: 10.1073/pnas.94.7.3380  0.336
1997 Silva AJ, Frankland PW, Marowitz Z, Friedman E, Laszlo GS, Cioffi D, Jacks T, Bourtchuladze R, Lazlo G. A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nature Genetics. 15: 281-4. PMID 9054942 DOI: 10.1038/Ng0397-281  0.675
1997 Kogan JH, Frankland PW, Blendy JA, Coblentz J, Marowitz Z, Schütz G, Silva AJ. Spaced training induces normal long-term memory in CREB mutant mice. Current Biology : Cb. 7: 1-11. PMID 8999994 DOI: 10.1016/S0960-9822(06)00022-4  0.693
1996 Silva AJ, Fedorov N, Kogan J, Frankland P, Coblentz J, Lundsten R, Friedman E, Smith A, Cho Y, Giese KP. Genetic analysis of function and dysfunction in the central nervous system Cold Spring Harbor Symposia On Quantitative Biology. 61: 239-246. PMID 9246452 DOI: 10.1101/Sqb.1996.061.01.026  0.624
1996 Silva AJ, Rosahl TW, Chapman PF, Marowitz Z, Friedman E, Frankland PW, Cestari V, Cioffi D, Südhof TC, Bourtchuladze R. Impaired learning in mice with abnormal short-lived plasticity. Current Biology : Cb. 6: 1509-18. PMID 8939606 DOI: 10.1016/S0960-9822(96)00756-7  0.667
1996 Gordon JA, Cioffi D, Silva AJ, Stryker MP. Deficient plasticity in the primary visual cortex of alpha-calcium/calmodulin-dependent protein kinase II mutant mice. Neuron. 17: 491-9. PMID 8816712 DOI: 10.1016/S0896-6273(00)80181-6  0.333
1996 Glazewski S, Chen CM, Silva A, Fox K. Requirement for alpha-CaMKII in experience-dependent plasticity of the barrel cortex. Science (New York, N.Y.). 272: 421-3. PMID 8602534 DOI: 10.1126/Science.272.5260.421  0.338
1996 Wehner JM, Silva A. Importance of strain differences in evaluations of learning and memory processes in null mutants Mental Retardation and Developmental Disabilities Research Reviews. 2: 243-248. DOI: 10.1002/(Sici)1098-2779(1996)2:4<243::Aid-Mrdd8>3.0.Co;2-R  0.44
1995 Butler LS, Silva AJ, Abeliovich A, Watanabe Y, Tonegawa S, McNamara JO. Limbic epilepsy in transgenic mice carrying a Ca2+/calmodulin-dependent kinase II alpha-subunit mutation. Proceedings of the National Academy of Sciences of the United States of America. 92: 6852-5. PMID 7624331 DOI: 10.1073/Pnas.92.15.6852  0.565
1995 Tonegawa S, Li Y, Erzurumlu RS, Jhaveri S, Chen C, Goda Y, Paylor R, Silva AJ, Kim JJ, Wehner JM. The gene knockout technology for the analysis of learning and memory, and neural development. Progress in Brain Research. 105: 3-14. PMID 7568891 DOI: 10.1016/S0079-6123(08)63279-3  0.597
1994 Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell. 79: 59-68. PMID 7923378 DOI: 10.1016/0092-8674(94)90400-6  0.464
1994 Silva AJ, Giese KP. Plastic genes are in! Current Opinion in Neurobiology. 4: 413-420. PMID 7919937 DOI: 10.1016/0959-4388(94)90104-X  0.442
1994 Grant SGN, Silva AJ. Targeting learning Trends in Neurosciences. 17: 71-75. PMID 7512771 DOI: 10.1016/0166-2236(94)90077-9  0.341
1993 Silva AJ, Paylor R, Wehner JM, Tonegawa S. Responses. Science (New York, N.Y.). 262: 761-2. PMID 17812342 DOI: 10.1126/science.262.5134.761  0.341
1993 Abeliovich A, Chen C, Goda Y, Silva AJ, Stevens CF, Tonegawa S. Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell. 75: 1253-62. PMID 8269509 DOI: 10.1016/0092-8674(93)90613-U  0.533
1992 Silva AJ, Stevens CF, Tonegawa S, Wang Y. Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science (New York, N.Y.). 257: 201-6. PMID 1378648 DOI: 10.1126/Science.1378648  0.563
1992 Silva AJ, Wang Y, Paylor R, Wehner JM, Stevens CF, Tonegawa S. Alpha calcium/calmodulin kinase II mutant mice: deficient long-term potentiation and impaired spatial learning. Cold Spring Harbor Symposia On Quantitative Biology. 57: 527-39. PMID 1339689 DOI: 10.1101/Sqb.1992.057.01.058  0.537
1992 Silva AJ, Paylor R, Wehner JM, Tonegawa S. Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science (New York, N.Y.). 257: 206-11. PMID 1321493 DOI: 10.1126/Science.1321493  0.615
1988 Silva AJ, White R. Inheritance of allelic blueprints for methylation patterns Cell. 54: 145-152. PMID 2898978 DOI: 10.1016/0092-8674(88)90546-6  0.405
1988 Nakamura Y, Martin C, Silva A, Leppert M, O'Connell P, Lathrop GM, Lalouel JM, White R. Isolation and mapping of a polymorphic DNA sequence (pCMI37) on chromosome 7 [D7S368]. Nucleic Acids Research. 16: 4192. PMID 2897676 DOI: 10.1093/Nar/16.9.4192  0.383
1987 Silva AJ, Johnson JP, White RL. Characterization of a highly polymorphic region 5' to JH in the human immunoglobulin heavy chain. Nucleic Acids Research. 15: 3845-57. PMID 2884636 DOI: 10.1093/nar/15.9.3845  0.407
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