Alexander Meissner - Publications

Affiliations: 
Biology, Molecular and Cellular Harvard University, Cambridge, MA, United States 
Area:
Genetics, Neuroscience Biology

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hetzel S, Mattei AL, Kretzmer H, Qu C, Chen X, Fan Y, Wu G, Roberts KG, Luger S, Litzow M, Rowe J, Paietta E, Stock W, Mardis ER, Wilson RK, ... ... Meissner A, et al. Acute lymphoblastic leukemia displays a distinct highly methylated genome. Nature Cancer. PMID 35590059 DOI: 10.1038/s43018-022-00370-5  0.35
2021 Blanco MA, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, Jambhekar A, Cheloufi S, Meissner A, Hochedlinger K, Scadden DT, et al. Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports. 37: 109967. PMID 34758323 DOI: 10.1016/j.celrep.2021.109967  0.342
2021 Andergassen D, Smith ZD, Kretzmer H, Rinn JL, Meissner A. Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages. Developmental Cell. 56: 2995-3005.e4. PMID 34752748 DOI: 10.1016/j.devcel.2021.10.010  0.309
2021 Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, ... ... Meissner A, et al. Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells. Genes & Development. PMID 34413137 DOI: 10.1101/gad.348678.121  0.441
2021 Wu HJ, Landshammer A, Stamenova EK, Bolondi A, Kretzmer H, Meissner A, Michor F. Topological isolation of developmental regulators in mammalian genomes. Nature Communications. 12: 4897. PMID 34385432 DOI: 10.1038/s41467-021-24951-7  0.315
2021 Gu H, Raman AT, Wang X, Gaiti F, Chaligne R, Mohammad AW, Arczewska A, Smith ZD, Landau DA, Aryee MJ, Meissner A, Gnirke A. Smart-RRBS for single-cell methylome and transcriptome analysis. Nature Protocols. PMID 34244697 DOI: 10.1038/s41596-021-00571-9  0.383
2021 Haggerty C, Kretzmer H, Riemenschneider C, Kumar AS, Mattei AL, Bailly N, Gottfreund J, Giesselmann P, Weigert R, Brändl B, Giehr P, Buschow R, Galonska C, von Meyenn F, Pappalardi MB, ... ... Meissner A, et al. Dnmt1 has de novo activity targeted to transposable elements. Nature Structural & Molecular Biology. PMID 34140676 DOI: 10.1038/s41594-021-00603-8  0.366
2021 Kretzmer H, Biran A, Purroy N, Lemvigh C, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes S, ... ... Meissner A, et al. Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy. Blood Cancer Discovery. 2: 54-69. PMID 33604581 DOI: 10.1158/2643-3230.BCD-19-0058  0.34
2020 Grosswendt S, Kretzmer H, Smith ZD, Kumar AS, Hetzel S, Wittler L, Klages S, Timmermann B, Mukherji S, Meissner A. Epigenetic regulator function through mouse gastrulation. Nature. 584: 102-108. PMID 32728215 DOI: 10.1038/S41586-020-2552-X  0.48
2020 Yagi M, Kabata M, Tanaka A, Ukai T, Ohta S, Nakabayashi K, Shimizu M, Hata K, Meissner A, Yamamoto T, Yamada Y. Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development. Nature Communications. 11: 3199. PMID 32581223 DOI: 10.1038/S41467-020-16989-W  0.439
2020 Charlton J, Jung EJ, Mattei AL, Bailly N, Liao J, Martin EJ, Giesselmann P, Brändl B, Stamenova EK, Müller FJ, Kiskinis E, Gnirke A, Smith ZD, Meissner A. TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers. Nature Genetics. PMID 32514123 DOI: 10.1038/S41588-020-0639-9  0.548
2020 Basu S, Mackowiak SD, Niskanen H, Knezevic D, Asimi V, Grosswendt S, Geertsema H, Ali S, Jerković I, Ewers H, Mundlos S, Meissner A, Ibrahim DM, Hnisz D. Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. Cell. PMID 32386547 DOI: 10.1016/J.Cell.2020.04.018  0.376
2020 Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, ... ... Meissner A, et al. Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling. Nature Cell Biology. PMID 32231305 DOI: 10.1038/S41556-020-0483-2  0.349
2020 Gokhman D, Nissim-Rafinia M, Agranat-Tamir L, Housman G, García-Pérez R, Lizano E, Cheronet O, Mallick S, Nieves-Colón MA, Li H, Alpaslan-Roodenberg S, Novak M, Gu H, Osinski JM, Ferrando-Bernal M, ... ... Meissner A, et al. Differential DNA methylation of vocal and facial anatomy genes in modern humans. Nature Communications. 11: 1189. PMID 32132541 DOI: 10.1038/S41467-020-15020-6  0.436
2019 Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA. Circadian Entrainment Triggers Maturation of Human In Vitro Islets. Cell Stem Cell. PMID 31839570 DOI: 10.1016/J.Stem.2019.11.011  0.419
2019 Giesselmann P, Brändl B, Raimondeau E, Bowen R, Rohrandt C, Tandon R, Kretzmer H, Assum G, Galonska C, Siebert R, Ammerpohl O, Heron A, Schneider SA, Ladewig J, Koch P, ... ... Meissner A, et al. Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing. Nature Biotechnology. PMID 31740840 DOI: 10.1038/S41587-019-0293-X  0.348
2019 Andergassen D, Smith ZD, Lewandowski JP, Gerhardinger C, Meissner A, Rinn JL. In vivo and deletion elucidates roles for autosomal gene regulation. Elife. 8. PMID 31738164 DOI: 10.7554/Elife.47214  0.332
2019 Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, ... ... Meissner A, et al. Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. PMID 31695192 DOI: 10.1038/S41586-019-1696-Z  0.33
2019 Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, et al. Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology. PMID 31659274 DOI: 10.1038/S41556-019-0403-5  0.452
2019 Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, ... ... Meissner A, et al. The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell. PMID 31588046 DOI: 10.1016/J.Stem.2019.08.018  0.478
2019 Thakurela S, Sindhu C, Yurkovsky E, Riemenschneider C, Smith ZD, Nachman I, Meissner A. Differential regulation of OCT4 targets facilitates reacquisition of pluripotency. Nature Communications. 10: 4444. PMID 31570708 DOI: 10.1038/S41467-019-11741-5  0.793
2019 Tsankov AM, Wadsworth MH, Akopian V, Charlton J, Allon SJ, Arczewska A, Mead BE, Drake RS, Smith ZD, Mikkelsen TS, Shalek AK, Meissner A. Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development (Cambridge, England). 146. PMID 31515224 DOI: 10.1242/Dev.174722  0.542
2019 Jönsson ME, Ludvik Brattås P, Gustafsson C, Petri R, Yudovich D, Pircs K, Verschuere S, Madsen S, Hansson J, Larsson J, Månsson R, Meissner A, Jakobsson J. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nature Communications. 10: 3182. PMID 31320637 DOI: 10.1038/S41467-019-11150-8  0.454
2019 Gaiti F, Chaligne R, Gu H, Brand RM, Kothen-Hill S, Schulman RC, Grigorev K, Risso D, Kim KT, Pastore A, Huang KY, Alonso A, Sheridan C, Omans ND, Biederstedt E, ... ... Meissner A, et al. Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature. PMID 31092926 DOI: 10.1038/S41586-019-1198-Z  0.438
2019 Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Molecular recording of mammalian embryogenesis. Nature. PMID 31086336 DOI: 10.1038/S41586-019-1184-5  0.418
2019 Modic M, Grosch M, Rot G, Schirge S, Lepko T, Yamazaki T, Lee FCY, Rusha E, Shaposhnikov D, Palo M, Merl-Pham J, Cacchiarelli D, Rogelj B, Hauck SM, von Mering C, ... Meissner A, et al. Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell. PMID 31047794 DOI: 10.1016/J.Molcel.2019.03.041  0.437
2019 Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, ... ... Meissner A, et al. Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications. 10: 1874. PMID 31015400 DOI: 10.1038/S41467-019-09645-5  0.463
2019 Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, et al. Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience. 22: 37-46. PMID 30559478 DOI: 10.1038/S41593-018-0291-1  0.343
2019 Biran A, Kretzmer H, Yin S, Billington L, Regis FF, Mohammad AW, Gnirke A, Neuberg DS, Carrasco RD, Meissner A, Wu CJ. Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo Blood. 134: 1737-1737. DOI: 10.1182/Blood-2019-130744  0.39
2018 Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, ... ... Meissner A, et al. KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell. PMID 30472020 DOI: 10.1016/J.Ccell.2018.10.014  0.313
2018 Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A. Targets and genomic constraints of ectopic Dnmt3b expression. Elife. 7. PMID 30468428 DOI: 10.7554/Elife.40757  0.467
2018 Ichida JK, Staats KA, Davis-Dusenbery BN, Clement K, Galloway KE, Babos KN, Shi Y, Son EY, Kiskinis E, Atwater N, Gu H, Gnirke A, Meissner A, Eggan K. Comparative genomic analysis of embryonic, lineage-converted, and stem cell-derived motor neurons. Development (Cambridge, England). PMID 30337375 DOI: 10.1242/Dev.168617  0.412
2018 Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C. Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cell Systems. PMID 30195438 DOI: 10.1016/J.Cels.2018.07.006  0.434
2018 Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, et al. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature Methods. PMID 30127506 DOI: 10.1038/S41592-018-0104-1  0.449
2018 Rajavelu A, Lungu C, Emperle M, Dukatz M, Bröhm A, Broche J, Hanelt I, Parsa E, Schiffers S, Karnik R, Meissner A, Carell T, Rathert P, Jurkowska RZ, Jeltsch A. Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research. PMID 30102379 DOI: 10.1093/Nar/Gky715  0.425
2018 Schwarz BA, Cetinbas M, Clement K, Walsh RM, Cheloufi S, Gu H, Langkabel J, Kamiya A, Schorle H, Meissner A, Sadreyev RI, Hochedlinger K. Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming. Cell Stem Cell. PMID 30017590 DOI: 10.1016/J.Stem.2018.06.013  0.553
2018 Du P, Pirouz M, Choi J, Huebner AJ, Clement K, Meissner A, Hochedlinger K, Gregory RI. An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. Cell Stem Cell. PMID 29804889 DOI: 10.1016/J.Stem.2018.04.021  0.345
2018 Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, et al. Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Reports. 23: 2509-2523. PMID 29791859 DOI: 10.1016/J.Celrep.2018.04.066  0.327
2018 Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. PMID 29681539 DOI: 10.1016/J.Stemcr.2018.03.019  0.506
2018 Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, ... ... Meissner A, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 22: 575-588.e7. PMID 29625070 DOI: 10.1016/J.Stem.2018.03.012  0.412
2018 Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, et al. Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell. PMID 29551301 DOI: 10.1016/J.Stem.2018.02.012  0.506
2018 Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A. Global delay in nascent strand DNA methylation. Nature Structural & Molecular Biology. PMID 29531288 DOI: 10.1038/S41594-018-0046-4  0.524
2018 Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, ... Meissner A, et al. Genome-wide tracking of dCas9-methyltransferase footprints. Nature Communications. 9: 597. PMID 29426832 DOI: 10.1038/S41467-017-02708-5  0.457
2018 Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, ... ... Meissner A, et al. Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nature Genetics. PMID 29358654 DOI: 10.1038/S41588-017-0034-3  0.781
2018 Chaligne R, Gaiti F, Izzo F, Kothen-Hill S, Gu H, Huang K, Risso D, Schulman R, Brand RM, Lee SC, Poran A, Kim K, Pastore A, Alonso A, Gnirke A, ... ... Meissner A, et al. Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution Blood. 132: 1312-1312. DOI: 10.1182/Blood-2018-99-115596  0.444
2017 Smith ZD, Shi J, Gu H, Donaghey J, Clement K, Cacchiarelli D, Gnirke A, Michor F, Meissner A. Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature. 549: 543-547. PMID 28959968 DOI: 10.1038/Nature23891  0.473
2017 Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, ... ... Meissner A, et al. Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature. PMID 28746311 DOI: 10.1038/Nature23274  0.459
2017 Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MH, Tsankov AM, Duberow E, ... ... Meissner A, et al. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell. 20: 547-557.e7. PMID 28388431 DOI: 10.1016/J.Stem.2017.01.010  0.407
2017 Choi J, Clement K, Huebner AJ, Webster J, Rose CM, Brumbaugh J, Walsh RM, Lee S, Savol A, Etchegaray JP, Gu H, Boyle P, Elling U, Mostoslavsky R, Sadreyev R, ... ... Meissner A, et al. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell. PMID 28366588 DOI: 10.1016/J.Stem.2017.03.002  0.778
2017 Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 168: 944-945. PMID 28235203 DOI: 10.1016/J.Cell.2017.02.010  0.382
2016 Liu LL, Brumbaugh J, Bar-Nur O, Smith Z, Stadtfeld M, Meissner A, Hochedlinger K, Michor F. Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells. Cell Reports. 17: 3395-3406. PMID 28009305 DOI: 10.1016/J.Celrep.2016.11.080  0.447
2016 Ziller MJ, Stamenova EK, Gu H, Gnirke A, Meissner A. Targeted bisulfite sequencing of the dynamic DNA methylome. Epigenetics & Chromatin. 9: 55. PMID 27980681 DOI: 10.1186/S13072-016-0105-1  0.433
2016 Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT. Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 167: 1310-1322.e17. PMID 27863245 DOI: 10.1016/j.cell.2016.10.045  0.394
2016 Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, ... ... Meissner A, et al. LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. PMID 27799657 DOI: 10.1038/Nature20132  0.423
2016 Aguilar CA, Pop R, Shcherbina A, Watts A, Matheny RW, Cacchiarelli D, Han WM, Shin E, Nakhai SA, Jang YC, Carrigan CT, Gifford CA, Kottke MA, Cesana M, Lee J, ... ... Meissner A, et al. Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports. PMID 27773702 DOI: 10.1016/J.Stemcr.2016.09.009  0.756
2016 Libertini E, Heath SC, Hamoudi RA, Gut M, Ziller MJ, Czyz A, Ruotti V, Stunnenberg HG, Frontini M, Ouwehand WH, Meissner A, Gut IG, Beck S. Information recovery from low coverage whole-genome bisulfite sequencing. Nature Communications. 7: 11306. PMID 27346250 DOI: 10.1038/Ncomms11306  0.409
2016 Smith ZD, Sindhu C, Meissner A. Molecular features of cellular reprogramming and development. Nature Reviews. Molecular Cell Biology. 17: 139-54. PMID 26883001 DOI: 10.1038/Nrm.2016.6  0.493
2016 Landau DA, Clement K, Gu H, Biederstedt E, Kangeyan D, Hill S, Wang L, Aryee M, Gnirke A, Meissner A, Wu CJ. Single Cell Bisulfite Sequencing Defines Epigenetic Diversification in Chronic Lymphocytic Leukemia Blood. 128: 1047-1047. DOI: 10.1182/Blood.V128.22.1047.1047  0.44
2015 Shea JM, Serra RW, Carone BR, Shulha HP, Kucukural A, Ziller MJ, Vallaster MP, Gu H, Tapper AR, Gardner PD, Meissner A, Garber M, Rando OJ. Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome. Developmental Cell. 35: 750-8. PMID 26702833 DOI: 10.1016/J.Devcel.2015.11.024  0.386
2015 Tsankov AM, Akopian V, Pop R, Chetty S, Gifford CA, Daheron L, Tsankova NM, Meissner A. A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells. Nature Biotechnology. 33: 1182-92. PMID 26501952 DOI: 10.1038/Nbt.3387  0.77
2015 Choi J, Lee S, Mallard W, Clement K, Tagliazucchi GM, Lim H, Choi IY, Ferrari F, Tsankov AM, Pop R, Lee G, Rinn JL, Meissner A, Park PJ, Hochedlinger K. A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs. Nature Biotechnology. PMID 26501951 DOI: 10.1038/Nbt.3388  0.442
2015 Aguilar CA, Shcherbina A, Ricke DO, Pop R, Carrigan CT, Gifford CA, Urso ML, Kottke MA, Meissner A. In vivo Monitoring of Transcriptional Dynamics After Lower-Limb Muscle Injury Enables Quantitative Classification of Healing. Scientific Reports. 5: 13885. PMID 26381351 DOI: 10.1038/Srep13885  0.734
2015 Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, ... ... Meissner A, et al. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Reports. 12: 1456-1470. PMID 26299972 DOI: 10.1016/J.Celrep.2015.07.053  0.467
2015 Paull D, Sevilla A, Zhou H, Hahn AK, Kim H, Napolitano C, Tsankov A, Shang L, Krumholz K, Jagadeesan P, Woodard CM, Sun B, Vilboux T, Zimmer M, Forero E, ... ... Meissner A, et al. Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells. Nature Methods. PMID 26237226 DOI: 10.1038/Nmeth.3507  0.397
2015 Galonska C, Ziller MJ, Karnik R, Meissner A. Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming. Cell Stem Cell. 17: 462-70. PMID 26235340 DOI: 10.1016/J.Stem.2015.07.005  0.448
2015 Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, ... ... Meissner A, et al. Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency. Cell. 162: 412-424. PMID 26186193 DOI: 10.1016/J.Cell.2015.06.016  0.772
2015 Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, et al. Corrigendum: DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nature Communications. 6: 7740. PMID 26151124 DOI: 10.1038/Ncomms8740  0.316
2015 Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA. Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies. The International Journal of Biochemistry & Cell Biology. PMID 26003740 DOI: 10.1016/J.Biocel.2015.05.009  0.372
2015 Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, ... ... Meissner A, et al. Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nature Genetics. 47: 469-78. PMID 25822089 DOI: 10.1038/Ng.3258  0.796
2015 Edri R, Yaffe Y, Ziller MJ, Mutukula N, Volkman R, David E, Jacob-Hirsch J, Malcov H, Levy C, Rechavi G, Gat-Viks I, Meissner A, Elkabetz Y. Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nature Communications. 6: 6500. PMID 25799239 DOI: 10.1038/Ncomms7500  0.445
2015 Dahlberg A, Woo S, Delaney C, Boyle P, Gnirke A, Bock C, Bernstein BE, Meissner A, Gottardo R, Bernstein ID. Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity. Leukemia. PMID 25742749 DOI: 10.1038/Leu.2015.61  0.356
2015 Tsankov AM, Gu H, Akopian V, Ziller MJ, Donaghey J, Amit I, Gnirke A, Meissner A. Transcription factor binding dynamics during human ES cell differentiation. Nature. 518: 344-9. PMID 25693565 DOI: 10.1038/Nature14233  0.515
2015 Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, ... ... Meissner A, et al. Integrative analysis of 111 reference human epigenomes. Nature. 518: 317-30. PMID 25693563 DOI: 10.1038/Nature14248  0.45
2015 French A, Bravery C, Smith J, Chandra A, Archibald P, Gold JD, Artzi N, Kim HW, Barker RW, Meissner A, Wu JC, Knowles JC, Williams D, García-Cardeña G, Sipp D, et al. Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards. Stem Cells Translational Medicine. 4: 217-23. PMID 25650438 DOI: 10.5966/Sctm.2014-0233  0.365
2015 Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K. Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells. Stem Cell Reports. 4: 297-311. PMID 25619437 DOI: 10.1016/J.Stemcr.2014.12.009  0.307
2015 Pour M, Pilzer I, Rosner R, Smith ZD, Meissner A, Nachman I. Epigenetic predisposition to reprogramming fates in somatic cells. Embo Reports. 16: 370-8. PMID 25600117 DOI: 10.15252/Embr.201439264  0.475
2015 Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, ... ... Meissner A, et al. Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 518: 355-9. PMID 25533951 DOI: 10.1038/Nature13990  0.788
2015 Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, ... ... Meissner A, et al. A comparison of non-integrating reprogramming methods. Nature Biotechnology. 33: 58-63. PMID 25437882 DOI: 10.1038/Nbt.3070  0.343
2015 Yu L, Chibnik LB, Srivastava GP, Pochet N, Yang J, Xu J, Kozubek J, Obholzer N, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA. Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease. Jama Neurology. 72: 15-24. PMID 25365775 DOI: 10.1001/Jamaneurol.2014.3049  0.334
2015 Ziller MJ, Hansen KD, Meissner A, Aryee MJ. Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing. Nature Methods. 12: 230-2, 1 p following. PMID 25362363 DOI: 10.1038/Nmeth.3152  0.345
2015 Beerman I, Ziller M, Vandiver A, Gaudin R, Kirchhausen T, Feinberg A, Meissner A, Rossi D. AGE-associated clonal dominance of myeloid-biased HSC is underwritten by unique transcriptional and epigenetic alterations Experimental Hematology. 43: S49. DOI: 10.1016/J.Exphem.2015.06.065  0.376
2014 Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, et al. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 159: 1681-97. PMID 25525883 DOI: 10.1016/J.Cell.2014.11.040  0.447
2014 Landau DA, Clement K, Ziller MJ, Boyle P, Fan J, Gu H, Stevenson K, Sougnez C, Wang L, Li S, Kotliar D, Zhang W, Ghandi M, Garraway L, Fernandes SM, ... ... Meissner A, et al. Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia. Cancer Cell. 26: 813-25. PMID 25490447 DOI: 10.1016/J.Ccell.2014.10.012  0.414
2014 Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, et al. DNA methylation signatures link prenatal famine exposure to growth and metabolism. Nature Communications. 5: 5592. PMID 25424739 DOI: 10.1038/Ncomms6592  0.427
2014 Li W, Cavelti-Weder C, Zhang Y, Clement K, Donovan S, Gonzalez G, Zhu J, Stemann M, Xu K, Hashimoto T, Yamada T, Nakanishi M, Zhang Y, Zeng S, Gifford D, ... Meissner A, et al. Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells. Nature Biotechnology. 32: 1223-30. PMID 25402613 DOI: 10.1038/Nbt.3082  0.374
2014 De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, ... ... Meissner A, et al. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature Neuroscience. 17: 1156-63. PMID 25129075 DOI: 10.1038/Nn.3786  0.355
2014 Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A. DNA methylation dynamics of the human preimplantation embryo. Nature. 511: 611-5. PMID 25079558 DOI: 10.1038/Nature13581  0.524
2014 Ichida JK, TCW J, T C W J, Williams LA, Carter AC, Shi Y, Moura MT, Ziller M, Singh S, Amabile G, Bock C, Umezawa A, Rubin LL, Bradner JE, Akutsu H, ... Meissner A, et al. Notch inhibition allows oncogene-independent generation of iPS cells. Nature Chemical Biology. 10: 632-9. PMID 24952596 DOI: 10.1038/Nchembio.1552  0.435
2014 Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, Wang H, Le T, Faull KF, Chen R, Gu H, Bock C, Meissner A, Göttgens B, Darlington GJ, et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 14: 673-88. PMID 24792119 DOI: 10.1016/J.Stem.2014.03.002  0.439
2014 Galonska C, Smith ZD, Meissner A. In Vivo and in vitro dynamics of undifferentiated embryonic cell transcription factor 1. Stem Cell Reports. 2: 245-52. PMID 24672748 DOI: 10.1016/J.Stemcr.2014.01.007  0.486
2014 Federation AJ, Bradner JE, Meissner A. The use of small molecules in somatic-cell reprogramming. Trends in Cell Biology. 24: 179-87. PMID 24183602 DOI: 10.1016/J.Tcb.2013.09.011  0.36
2014 Lord AM, Clement K, Schneider RK, Marie M, Chen MC, Levine RL, Mullally A, Galili N, Ali AM, Raza A, Bejar R, Meissner A, Ebert BL. Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing Blood. 124: 775-775. DOI: 10.1182/Blood.V124.21.775.775  0.452
2013 Michels KB, Binder AM, Dedeurwaerder S, Epstein CB, Greally JM, Gut I, Houseman EA, Izzi B, Kelsey KT, Meissner A, Milosavljevic A, Siegmund KD, Bock C, Irizarry RA. Recommendations for the design and analysis of epigenome-wide association studies. Nature Methods. 10: 949-55. PMID 24076989 DOI: 10.1038/Nmeth.2632  0.333
2013 Stelzer Y, Ronen D, Bock C, Boyle P, Meissner A, Benvenisty N. Identification of novel imprinted differentially methylated regions by global analysis of human-parthenogenetic-induced pluripotent stem cells. Stem Cell Reports. 1: 79-89. PMID 24052944 DOI: 10.1016/J.Stemcr.2013.03.005  0.493
2013 Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. Charting a dynamic DNA methylation landscape of the human genome. Nature. 500: 477-81. PMID 23925113 DOI: 10.1038/Nature12433  0.519
2013 Kearns NA, Genga RM, Ziller M, Kapinas K, Peters H, Brehm MA, Meissner A, Maehr R. Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules. Stem Cell Research. 11: 1003-12. PMID 23917481 DOI: 10.1016/J.Scr.2013.06.007  0.362
2013 Karnik R, Meissner A. Browsing (Epi)genomes: a guide to data resources and epigenome browsers for stem cell researchers. Cell Stem Cell. 13: 14-21. PMID 23827707 DOI: 10.1016/J.Stem.2013.06.006  0.461
2013 Zhang RR, Cui QY, Murai K, Lim YC, Smith ZD, Jin S, Ye P, Rosa L, Lee YK, Wu HP, Liu W, Xu ZM, Yang L, Ding YQ, Tang F, ... Meissner A, et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell. 13: 237-45. PMID 23770080 DOI: 10.1016/J.Stem.2013.05.006  0.389
2013 Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, ... ... Meissner A, et al. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell. 153: 1149-63. PMID 23664763 DOI: 10.1016/J.Cell.2013.04.037  0.81
2013 Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell. 12: 413-25. PMID 23415915 DOI: 10.1016/J.Stem.2013.01.017  0.455
2013 Smith ZD, Meissner A. DNA methylation: roles in mammalian development. Nature Reviews. Genetics. 14: 204-20. PMID 23400093 DOI: 10.1038/Nrg3354  0.491
2013 Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, ... ... Meissner A, et al. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell. 152: 642-54. PMID 23333102 DOI: 10.1016/J.Cell.2012.12.033  0.44
2013 Ogino S, Lochhead P, Chan AT, Nishihara R, Cho E, Wolpin BM, Meyerhardt JA, Meissner A, Schernhammer ES, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 26: 465-84. PMID 23307060 DOI: 10.1038/Modpathol.2012.214  0.396
2013 Smith ZD, Meissner A. The simplest explanation: passive DNA demethylation in PGCs. The Embo Journal. 32: 318-21. PMID 23299938 DOI: 10.1038/Emboj.2012.349  0.453
2013 Landau D, Clement K, Boyle P, Ziller M, Stevenson KE, Kotliar D, Saksena G, Eng M, Sougnez C, Zhang W, Ghandi M, Garraway L, Gabriel S, Lander ES, Brown JR, ... ... Meissner A, et al. Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution Blood. 122: 596-596. DOI: 10.1182/Blood.V122.21.596.596  0.459
2012 Meissner A. What can epigenomics do for you? Genome Biology. 13: 420. PMID 23095436 DOI: 10.1186/Gb-2012-13-10-420  0.374
2012 Boyle P, Clement K, Gu H, Smith ZD, Ziller M, Fostel JL, Holmes L, Meldrim J, Kelley F, Gnirke A, Meissner A. Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling. Genome Biology. 13: R92. PMID 23034176 DOI: 10.1186/Gb-2012-13-10-R92  0.39
2012 Sindhu C, Samavarchi-Tehrani P, Meissner A. Transcription factor-mediated epigenetic reprogramming. The Journal of Biological Chemistry. 287: 30922-31. PMID 22952239 DOI: 10.1074/Jbc.R111.319046  0.455
2012 Gifford CA, Meissner A. Epigenetic obstacles encountered by transcription factors: reprogramming against all odds. Current Opinion in Genetics & Development. 22: 409-15. PMID 22922161 DOI: 10.1016/J.Gde.2012.08.002  0.772
2012 Chan MM, Smith ZD, Egli D, Regev A, Meissner A. Mouse ooplasm confers context-specific reprogramming capacity. Nature Genetics. 44: 978-80. PMID 22902786 DOI: 10.1038/Ng.2382  0.445
2012 Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Molecular Cell. 47: 633-47. PMID 22841485 DOI: 10.1016/J.Molcel.2012.06.019  0.527
2012 Arand J, Spieler D, Karius T, Branco MR, Meilinger D, Meissner A, Jenuwein T, Xu G, Leonhardt H, Wolf V, Walter J. In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. Plos Genetics. 8: e1002750. PMID 22761581 DOI: 10.1371/Journal.Pgen.1002750  0.448
2012 Mekhoubad S, Bock C, de Boer AS, Kiskinis E, Meissner A, Eggan K. Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell. 10: 595-609. PMID 22560080 DOI: 10.1016/J.Stem.2012.02.014  0.389
2012 Brinkman AB, Gu H, Bartels SJ, Zhang Y, Matarese F, Simmer F, Marks H, Bock C, Gnirke A, Meissner A, Stunnenberg HG. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome Research. 22: 1128-38. PMID 22466170 DOI: 10.1101/Gr.133728.111  0.469
2012 Smith ZD, Chan MM, Mikkelsen TS, Gu H, Gnirke A, Regev A, Meissner A. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature. 484: 339-44. PMID 22456710 DOI: 10.1038/Nature10960  0.461
2012 Akopian V, Chan MM, Clement K, Galonska C, Gifford CA, Lehtola E, Liao J, Samavarchi-Tehrani P, Sindhu C, Smith ZD, Tsankov AM, Webster J, Zhang Y, Ziller MJ, Meissner A. Epigenomics and chromatin dynamics. Genome Biology. 13: 313. PMID 22364154 DOI: 10.1186/Gb-2012-13-2-313  0.721
2012 Xi Y, Bock C, Müller F, Sun D, Meissner A, Li W. RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing. Bioinformatics (Oxford, England). 28: 430-2. PMID 22155871 DOI: 10.1093/Bioinformatics/Btr668  0.325
2012 Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, et al. Dnmt3a is essential for hematopoietic stem cell differentiation. Nature Genetics. 44: 23-31. PMID 22138693 DOI: 10.1038/Ng.1009  0.485
2012 Xu H, Yi BA, Wu H, Bock C, Gu H, Lui KO, Park JH, Shao Y, Riley AK, Domian IJ, Hu E, Willette R, Lepore J, Meissner A, Wang Z, et al. Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Research. 22: 142-54. PMID 22064699 DOI: 10.1038/Cr.2011.171  0.472
2012 Jager PD, Srivastava G, Eaton M, Chibnik L, Keenan B, Zou F, Song H, Younkin C, Younkin S, Ertekin-Taner N, Bernstein B, Meissner A, Kellis M, Bennett D. Genome-wide exploration of DNA methylation in the aging brain and its relation to Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1829  0.341
2012 Keenan B, Srivastava G, Eaton M, Schneider J, Chibnik L, Meissner A, Kellis M, Bennett D, Jager PD. The role of DNA methylation in Alzheimer's susceptibility genes with Alzheimer's disease phenotypes Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1203  0.325
2011 Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A. Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. Plos Genetics. 7: e1002389. PMID 22174693 DOI: 10.1371/Journal.Pgen.1002389  0.474
2011 Shearstone JR, Pop R, Bock C, Boyle P, Meissner A, Socolovsky M. Global DNA demethylation during mouse erythropoiesis in vivo. Science (New York, N.Y.). 334: 799-802. PMID 22076376 DOI: 10.1126/Science.1207306  0.486
2011 Meissner A. Guiding DNA methylation. Cell Stem Cell. 9: 388-90. PMID 22056134 DOI: 10.1016/J.Stem.2011.10.014  0.426
2011 Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW, Zamponi R, Gazit R, Bock C, Jäger N, Smith ZD, Kim TM, Saunders AH, Wong J, Lee JH, ... ... Meissner A, et al. Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. Cell Stem Cell. 9: 272-81. PMID 21885022 DOI: 10.1016/J.Stem.2011.07.007  0.411
2011 Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, Yang X, Amit I, Meissner A, Regev A, Rinn JL, et al. lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature. 477: 295-300. PMID 21874018 DOI: 10.1038/Nature10398  0.447
2011 Thomson M, Liu SJ, Zou LN, Smith Z, Meissner A, Ramanathan S. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell. 145: 875-89. PMID 21663792 DOI: 10.1016/J.Cell.2011.05.017  0.471
2011 Gu H, Smith ZD, Bock C, Boyle P, Gnirke A, Meissner A. Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling. Nature Protocols. 6: 468-81. PMID 21412275 DOI: 10.1038/Nprot.2010.190  0.399
2011 Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith ZD, Ziller M, Croft GF, Amoroso MW, Oakley DH, Gnirke A, Eggan K, Meissner A. Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell. 144: 439-52. PMID 21295703 DOI: 10.1016/J.Cell.2010.12.032  0.465
2011 Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A. Reprogramming factor expression initiates widespread targeted chromatin remodeling. Cell Stem Cell. 8: 96-105. PMID 21211784 DOI: 10.1016/J.Stem.2010.12.001  0.519
2011 Jeong M, Sun D, Luo M, Ergen A, Gu H, Bock C, Meissner A, Darlington G, Li W, Goodell MA. Genome Wide DNA Methylation and Transcriptome Analysis in HSC Aging Blood. 118: 2367-2367. DOI: 10.1182/Blood.V118.21.2367.2367  0.477
2010 Tomazou EM, Meissner A. Epigenetic regulation of pluripotency. Advances in Experimental Medicine and Biology. 695: 26-40. PMID 21222197 DOI: 10.1007/978-1-4419-7037-4_3  0.532
2010 Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 143: 1084-96. PMID 21183072 DOI: 10.1016/J.Cell.2010.12.008  0.318
2010 Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/Jcb.201003048  0.349
2010 Meissner A. Epigenetic modifications in pluripotent and differentiated cells. Nature Biotechnology. 28: 1079-88. PMID 20944600 DOI: 10.1038/Nbt.1684  0.544
2010 Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell. 7: 618-30. PMID 20888316 DOI: 10.1016/J.Stem.2010.08.012  0.442
2010 Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, ... ... Meissner A, et al. Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nature Biotechnology. 28: 1097-105. PMID 20852635 DOI: 10.1038/Nbt.1682  0.447
2010 Bock C, Tomazou EM, Brinkman AB, Müller F, Simmer F, Gu H, Jäger N, Gnirke A, Stunnenberg HG, Meissner A. Quantitative comparison of genome-wide DNA methylation mapping technologies. Nature Biotechnology. 28: 1106-14. PMID 20852634 DOI: 10.1038/Nbt.1681  0.477
2010 Artyomov MN, Meissner A, Chakraborty AK. A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency. Plos Computational Biology. 6: e1000785. PMID 20485562 DOI: 10.1371/Journal.Pcbi.1000785  0.452
2010 Smith ZD, Nachman I, Regev A, Meissner A. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event. Nature Biotechnology. 28: 521-6. PMID 20436460 DOI: 10.1038/Nbt.1632  0.441
2010 Gu H, Bock C, Mikkelsen TS, Jäger N, Smith ZD, Tomazou E, Gnirke A, Lander ES, Meissner A. Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. Nature Methods. 7: 133-6. PMID 20062050 DOI: 10.1038/Nmeth.1414  0.399
2009 Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, ... ... Meissner A, et al. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science (New York, N.Y.). 326: 257-63. PMID 19729616 DOI: 10.1126/Science.1179050  0.379
2009 Smith ZD, Gu H, Bock C, Gnirke A, Meissner A. High-throughput bisulfite sequencing in mammalian genomes. Methods (San Diego, Calif.). 48: 226-32. PMID 19442738 DOI: 10.1016/J.Ymeth.2009.05.003  0.408
2009 Han DW, Do JT, Araúzo-Bravo MJ, Lee SH, Meissner A, Lee HT, Jaenisch R, Schöler HR. Epigenetic hierarchy governing Nestin expression. Stem Cells (Dayton, Ohio). 27: 1088-97. PMID 19415779 DOI: 10.1002/Stem.43  0.496
2009 Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 4: 200-1; author reply . PMID 19265657 DOI: 10.1016/J.Stem.2009.02.009  0.459
2009 Amabile G, Meissner A. Induced pluripotent stem cells: current progress and potential for regenerative medicine. Trends in Molecular Medicine. 15: 59-68. PMID 19162546 DOI: 10.1016/J.Molmed.2008.12.003  0.478
2009 Meissner A, Eminli S, Jaenisch R. Derivation and manipulation of murine embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 482: 3-19. PMID 19089346 DOI: 10.1007/978-1-59745-060-7_1  0.422
2008 Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/Nature07107  0.54
2008 Markoulaki S, Meissner A, Jaenisch R. Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse. Methods (San Diego, Calif.). 45: 101-14. PMID 18593608 DOI: 10.1016/J.Ymeth.2008.04.002  0.45
2008 Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/Nature07056  0.547
2008 Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, Van Neste L, Jaenisch R, Fan G. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell. 2: 160-9. PMID 18371437 DOI: 10.1016/J.Stem.2007.12.011  0.493
2008 Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2: 10-2. PMID 18371415 DOI: 10.1016/J.Stem.2007.12.001  0.351
2007 Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/Science.1152092  0.452
2007 Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes & Development. 21: 3110-22. PMID 18056424 DOI: 10.1101/Gad.1594007  0.403
2007 Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology. 25: 1177-81. PMID 17724450 DOI: 10.1038/Nbt1335  0.439
2007 Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Meissner A, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/Nature06008  0.504
2007 Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature. 448: 318-24. PMID 17554336 DOI: 10.1038/Nature05944  0.512
2007 Bernstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 128: 669-81. PMID 17320505 DOI: 10.1016/J.Cell.2007.01.033  0.42
2006 Meissner A, Jaenisch R. Mammalian nuclear transfer. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2460-9. PMID 16881069 DOI: 10.1002/Dvdy.20915  0.392
2006 Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells (Dayton, Ohio). 24: 2007-13. PMID 16709876 DOI: 10.1634/Stemcells.2006-0050  0.483
2006 Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041  0.524
2006 Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. Suppression of intestinal neoplasia by deletion of Dnmt3b. Molecular and Cellular Biology. 26: 2976-83. PMID 16581773 DOI: 10.1128/Mcb.26.8.2976-2983.2006  0.339
2006 Jaenisch R, Meissner A. Politically correct human embryonic stem cells? The New England Journal of Medicine. 354: 1208-9; author reply. PMID 16540629 DOI: 10.1056/Nejmc055530  0.376
2006 Meissner A, Jaenisch R. Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature. 439: 212-5. PMID 16227971 DOI: 10.1038/Nature04257  0.387
2005 Meissner A, Gnirke A, Bell GW, Ramsahoye B, Lander ES, Jaenisch R. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Research. 33: 5868-77. PMID 16224102 DOI: 10.1093/Nar/Gki901  0.42
2005 Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13580-5. PMID 16174748 DOI: 10.1073/Pnas.0506612102  0.376
2004 Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. Cre-lox-regulated conditional RNA interference from transgenes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10380-5. PMID 15240889 DOI: 10.1073/Pnas.0403954101  0.32
2004 Gaudet F, Rideout WM, Meissner A, Dausman J, Leonhardt H, Jaenisch R. Dnmt1 expression in pre- and postimplantation embryogenesis and the maintenance of IAP silencing. Molecular and Cellular Biology. 24: 1640-8. PMID 14749379 DOI: 10.1128/Mcb.24.4.1640-1648.2004  0.447
2003 Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (New York, N.Y.). 302: 885-9. PMID 14593183 DOI: 10.1126/Science.1086446  0.316
Show low-probability matches.