Stephen G. Holtzman - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
opioid dependence/withdrawal

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 White DA, Ballard ME, Harmon AC, Holtzman SG. Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumption. Brain Research Bulletin. 76: 597-604. PMID 18598850 DOI: 10.1016/j.brainresbull.2008.04.002  0.827
2008 White DA, Michaels CC, Holtzman SG. Periadolescent male but not female rats have higher motor activity in response to morphine than do adult rats. Pharmacology, Biochemistry, and Behavior. 89: 188-99. PMID 18206219 DOI: 10.1016/J.Pbb.2007.12.009  0.849
2008 Michaels CC, Holtzman SG. Early postnatal stress alters place conditioning to both mu- and kappa-opioid agonists. The Journal of Pharmacology and Experimental Therapeutics. 325: 313-8. PMID 18203949 DOI: 10.1124/Jpet.107.129908  0.836
2007 Skelton KH, Oren D, Gutman DA, Easterling K, Holtzman SG, Nemeroff CB, Owens MJ. The CRF1 receptor antagonist, R121919, attenuates the severity of precipitated morphine withdrawal. European Journal of Pharmacology. 571: 17-24. PMID 17610870 DOI: 10.1016/j.ejphar.2007.05.041  0.472
2007 Michaels CC, Easterling KW, Holtzman SG. Maternal separation alters ICSS responding in adult male and female rats, but morphine and naltrexone have little affect on that behavior. Brain Research Bulletin. 73: 310-8. PMID 17562397 DOI: 10.1016/J.Brainresbull.2007.04.008  0.784
2007 Michaels CC, Holtzman SG. Enhanced sensitivity to naltrexone-induced drinking suppression of fluid intake and sucrose consumption in maternally separated rats. Pharmacology, Biochemistry, and Behavior. 86: 784-96. PMID 17459462 DOI: 10.1016/J.Pbb.2007.03.007  0.792
2007 White DA, Kalinichev M, Holtzman SG. Locomotor response to novelty as a predictor of reactivity to aversive stimuli in the rat. Brain Research. 1149: 141-8. PMID 17383617 DOI: 10.1016/j.brainres.2007.02.050  0.543
2006 Michaels CC, Holtzman SG. Neonatal stress and litter composition alter sucrose intake in both rat dam and offspring. Physiology & Behavior. 89: 735-41. PMID 16996094 DOI: 10.1016/J.Physbeh.2006.08.015  0.755
2006 Joyce AR, Easterling K, Holtzman SG, Kuhar MJ. Modeling the onset of drug dependence: a consideration of the requirement for protein synthesis. Journal of Theoretical Biology. 240: 531-7. PMID 16352315 DOI: 10.1016/J.Jtbi.2005.10.012  0.472
2005 White DA, Holtzman SG. Periadolescent morphine exposure alters subsequent behavioral sensitivity to morphine in adult rats. European Journal of Pharmacology. 528: 119-23. PMID 16321380 DOI: 10.1016/j.ejphar.2005.10.026  0.625
2005 White DA, Hwang ML, Holtzman SG. Naltrexone-induced conditioned place aversion following a single dose of morphine in the rat. Pharmacology, Biochemistry, and Behavior. 81: 451-8. PMID 15907990 DOI: 10.1016/j.pbb.2005.04.002  0.743
2005 White DA, Holtzman SG. Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey: a further characterization. The Journal of Pharmacology and Experimental Therapeutics. 314: 374-82. PMID 15843500 DOI: 10.1124/jpet.104.078584  0.716
2005 Jain R, Holtzman SG. Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists. Brain Research Bulletin. 65: 415-21. PMID 15833596 DOI: 10.1016/j.brainresbull.2005.02.024  0.496
2004 Kalinichev M, White DA, Holtzman SG. Individual differences in locomotor reactivity to a novel environment and sensitivity to opioid drugs in the rat. I. Expression of morphine-induced locomotor sensitization. Psychopharmacology. 177: 61-7. PMID 15316716 DOI: 10.1007/s00213-004-1990-8  0.717
2004 White DA, Kalinichev M, Holtzman SG. Individual differences in locomotor reactivity to a novel environment and sensitivity to opioid drugs in the rat. II. Agonist-induced antinociception and antagonist-induced suppression of fluid consumption. Psychopharmacology. 177: 68-78. PMID 15235760 DOI: 10.1007/s00213-004-1921-8  0.732
2004 Easterling KW, Holtzman SG. In rats, acute morphine dependence results in antagonist-induced response suppression of intracranial self-stimulation. Psychopharmacology. 175: 287-95. PMID 15024547 DOI: 10.1007/s00213-004-1829-3  0.668
2003 White DA, Holtzman SG. Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey. Psychopharmacology. 167: 203-10. PMID 12644889 DOI: 10.1007/s00213-002-1367-9  0.718
2003 Holtzman SG. Discrimination of a single dose of morphine followed by naltrexone: substitution of other agonists for morphine and other antagonists for naltrexone in a rat model of acute dependence. The Journal of Pharmacology and Experimental Therapeutics. 304: 1033-41. PMID 12604679 DOI: 10.1124/jpet.102.044875  0.655
2003 Kalinichev M, Easterling KW, Holtzman SG. Long-lasting changes in morphine-induced locomotor sensitization and tolerance in Long-Evans mother rats as a result of periodic postpartum separation from the litter: a novel model of increased vulnerability to drug abuse? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 317-28. PMID 12589385 DOI: 10.1038/sj.npp.1300068  0.582
2003 Kalinichev M, Holtzman SG. Changes in urination/defecation, auditory startle response, and startle-induced ultrasonic vocalizations in rats undergoing morphine withdrawal: similarities and differences between acute and chronic dependence. The Journal of Pharmacology and Experimental Therapeutics. 304: 603-9. PMID 12538812 DOI: 10.1124/jpet.102.044206  0.621
2003 Kalinichev M, White D, Holtzman S. P.5.011 Individual reactivity to a novel environment predicts differences in anxiety-like behaviours and in morphine-induced locomotor sensitisation and tolerance in the rat European Neuropsychopharmacology. 13: S412-S413. DOI: 10.1016/S0924-977X(03)92260-7  0.475
2002 Kalinichev M, Easterling KW, Holtzman SG. Early neonatal experience of Long-Evans rats results in long-lasting changes in reactivity to a novel environment and morphine-induced sensitization and tolerance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 518-33. PMID 12377389 DOI: 10.1016/S0893-133X(02)00326-3  0.585
2002 Kalinichev M, Easterling KW, Plotsky PM, Holtzman SG. Long-lasting changes in stress-induced corticosterone response and anxiety-like behaviors as a consequence of neonatal maternal separation in Long-Evans rats. Pharmacology, Biochemistry, and Behavior. 73: 131-40. PMID 12076732 DOI: 10.1016/S0091-3057(02)00781-5  0.367
2002 Schad CA, Justice JB, Holtzman SG. Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. The Journal of Pharmacology and Experimental Therapeutics. 300: 932-8. PMID 11861800 DOI: 10.1124/Jpet.300.3.932  0.481
2001 Easterling KW, Holtzman SG. Central discriminative effects of morphine in rats: training via intracerebroventricular administration. Brain Research Bulletin. 56: 545-51. PMID 11786240 DOI: 10.1016/S0361-9230(01)00661-X  0.519
2001 Kalinichev M, Easterling KW, Holtzman SG. Early neonatal experience of Long-Evans rats results in long-lasting changes in morphine tolerance and dependence. Psychopharmacology. 157: 305-12. PMID 11605087 DOI: 10.1007/s002130100806  0.583
2001 Powell KR, Iuvone PM, Holtzman SG. The role of dopamine in the locomotor stimulant effects and tolerance to these effects of caffeine. Pharmacology, Biochemistry, and Behavior. 69: 59-70. PMID 11420069 DOI: 10.1016/S0091-3057(01)00497-X  0.463
2001 White DA, Holtzman SG. Acute opioid pretreatment potentiates naltrexone-induced drinking suppression in water-deprived rats. The Journal of Pharmacology and Experimental Therapeutics. 298: 156-64. PMID 11408537  0.686
2001 Kalinichev M, Easterling KW, Holtzman SG. Repeated neonatal maternal separation alters morphine-induced antinociception in male rats. Brain Research Bulletin. 54: 649-54. PMID 11403991 DOI: 10.1016/S0361-9230(01)00485-3  0.583
2001 Holtzman SG. Differential interaction of GBR 12909, a dopamine uptake inhibitor, with cocaine and methamphetamine in rats discriminating cocaine. Psychopharmacology. 155: 180-6. PMID 11401007 DOI: 10.1007/s002130100684  0.356
2001 Kimmel HL, Holtzman SG. Repeated cocaine administration does not alter morphine-induced rotational behavior in nigrally denervated rats. Behavioural Pharmacology. 12: 101-8. PMID 11396514  0.727
2001 Powell KR, Holtzman SG. Parametric evaluation of the development of sensitization to the effects of morphine on locomotor activity. Drug and Alcohol Dependence. 62: 83-90. PMID 11173171 DOI: 10.1016/S0376-8716(00)00167-8  0.57
2000 Bergman J, France CP, Holtzman SG, Katz JL, Koek W, Stephens DN. Agonist efficacy, drug dependence, and medications development: preclinical evaluation of opioid, dopaminergic, and GABAA-ergic ligands. Psychopharmacology. 153: 67-84. PMID 11255930 DOI: 10.1007/S002130000567  0.399
2000 Kalinichev M, Easterling KW, Holtzman SG. Periodic postpartum separation from the offspring results in long-lasting changes in anxiety-related behaviors and sensitivity to morphine in Long-Evans mother rats. Psychopharmacology. 152: 431-9. PMID 11140336 DOI: 10.1007/s002130000556  0.544
2000 Holtzman SG. Further characterization of the discriminative stimulus effects of spiradoline. Pharmacology, Biochemistry, and Behavior. 66: 517-22. PMID 10899364 DOI: 10.1016/S0091-3057(00)00172-6  0.63
2000 Easterling KW, Plovnick RM, Holtzman SG. Acute opioid but not benzodiazepine dependence in rats responding for intracranial self-stimulation. Psychopharmacology. 148: 263-71. PMID 10755739 DOI: 10.1007/S002130050050  0.643
2000 Powell KR, Holtzman SG. Modulation of the discriminative stimulus effects of d-amphetamine by mu and kappa opioids in squirrel monkeys. Pharmacology, Biochemistry, and Behavior. 65: 43-51. PMID 10638635 DOI: 10.1016/S0091-3057(99)00183-5  0.586
2000 Kalinichev M, Easterling K, Holtzman S. Periodic postpartum separation from the litter alters stress-reactivity and sensitivity to morphine in Long-Evans dams European Neuropsychopharmacology. 10: 375-376. DOI: 10.1016/S0924-977X(00)80509-X  0.45
1999 Powell KR, Koppelman LF, Holtzman SG. Differential involvement of dopamine in mediating the discriminative stimulus effects of low and high doses of caffeine in rats. Behavioural Pharmacology. 10: 707-16. PMID 10780285  0.361
1999 Volpicelli LA, Easterling KW, Kimmel HL, Holtzman SG. Sensitization to daily morphine injections in rats with unilateral lesions of the substantia nigra. Pharmacology, Biochemistry, and Behavior. 64: 487-93. PMID 10548260 DOI: 10.1016/S0091-3057(99)00098-2  0.786
1999 Powell KR, Holtzman SG. Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine. European Journal of Pharmacology. 377: 21-8. PMID 10448921 DOI: 10.1016/S0014-2999(99)00394-5  0.555
1999 Holtzman SG. Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, have a dopamine component in monkeys. European Journal of Pharmacology. 376: 7-15. PMID 10440083 DOI: 10.1016/S0014-2999(99)00346-5  0.4
1999 Easterling KW, Holtzman SG. Discriminative stimulus effects of naltrexone after a single dose of morphine in the rat. The Journal of Pharmacology and Experimental Therapeutics. 288: 1269-77. PMID 10027868  0.441
1999 Waddell AB, Holtzman SG. Modulation of cocaine-induced antinociception by opioid-receptor agonists. Pharmacology, Biochemistry, and Behavior. 62: 247-53. PMID 9972691 DOI: 10.1016/S0091-3057(98)00161-0  0.502
1998 Easterling KW, Holtzman SG. Comparison of the discriminative and antinociceptive effects of morphine and its glucuronide metabolites after central or systemic administration in the rat. Psychopharmacology. 140: 91-7. PMID 9862407 DOI: 10.1007/s002130050743  0.606
1998 Waddell AB, Holtzman SG. Modulation of cocaine-induced motor activity in the rat by opioid receptor agonists. Behavioural Pharmacology. 9: 397-407. PMID 9832925  0.46
1998 Kimmel HL, Justice JB, Holtzman SG. Dissociation of morphine-induced potentiation of turning and striatal dopamine release by amphetamine in the nigrally-lesioned rat. European Journal of Pharmacology. 346: 203-8. PMID 9652361 DOI: 10.1016/S0014-2999(98)00072-7  0.747
1998 Kimmel HL, Schad CA, Justice JB, Holtzman SG. Naloxone does not alter amphetamine-induced rotational behavior or striatal dopamine levels of nigrally-lesioned rats. Brain Research. 789: 171-4. PMID 9602114 DOI: 10.1016/S0006-8993(98)00098-5  0.721
1998 Kimmel HL, Holtzman SG. Opioid receptor agonists and antagonists alter GBR12909-induced turning in the rat. European Journal of Pharmacology. 343: 119-27. PMID 9570458 DOI: 10.1016/S0014-2999(97)01532-X  0.749
1998 Powell KR, Holtzman SG. Lack of NMDA receptor involvement in caffeine-induced locomotor stimulation and tolerance in rats. Pharmacology, Biochemistry, and Behavior. 59: 433-8. PMID 9476992 DOI: 10.1016/S0091-3057(97)00447-4  0.481
1997 Woolfolk DR, Holtzman SG. mu-, delta- and kappa-opioid receptor agonists do not alter the discriminative stimulus effects of cocaine or d-amphetamine in rats. Drug and Alcohol Dependence. 48: 209-20. PMID 9449020 DOI: 10.1016/S0376-8716(97)00129-4  0.552
1997 Tallarida RJ, Kimmel HL, Holtzman SG. Theory and statistics of detecting synergism between two active drugs: cocaine and buprenorphine. Psychopharmacology. 133: 378-82. PMID 9372538 DOI: 10.1007/s002130050417  0.628
1997 Kimmel HL, Tallarida RJ, Holtzman SG. Synergism between buprenorphine and cocaine on the rotational behavior of the nigrally-lesioned rat. Psychopharmacology. 133: 372-7. PMID 9372537 DOI: 10.1007/s002130050416  0.679
1997 Patterson AB, Gordon FJ, Holtzman SG. Naltrindole, a selective delta-opioid receptor antagonist, potentiates the lethal effects of cocaine by a central mechanism of action. European Journal of Pharmacology. 333: 47-54. PMID 9311660 DOI: 10.1016/S0014-2999(97)01090-X  0.467
1997 Kimmel HL, Holtzman SG. Mu opioid agonists potentiate amphetamine- and cocaine-induced rotational behavior in the rat. The Journal of Pharmacology and Experimental Therapeutics. 282: 734-46. PMID 9262337  0.764
1997 Holtzman SG. Antagonism of morphine-like discriminative effects by beta-funaltrexamine. Pharmacology, Biochemistry, and Behavior. 57: 771-7. PMID 9259005 DOI: 10.1016/S0091-3057(96)00395-4  0.554
1997 Holtzman SG. Discriminative stimulus effects of buprenorphine in the rat. Psychopharmacology. 130: 292-9. PMID 9151365 DOI: 10.1007/s002130050242  0.643
1997 Easterling KW, Holtzman SG. Intracranial self-stimulation in rats: sensitization to an opioid antagonist following acute or chronic treatment with mu opioid agonists. The Journal of Pharmacology and Experimental Therapeutics. 281: 188-99. PMID 9103497  0.576
1996 Woolfolk DR, Holtzman SG. The effects of opioid receptor antagonism on the discriminative stimulus effects of cocaine and d-amphetamine in the rat. Behavioural Pharmacology. 7: 779-787. PMID 11224472  0.496
1996 Schad CA, Justice JB, Holtzman SG. Differential effects of delta- and mu-opioid receptor antagonists on the amphetamine-induced increase in extracellular dopamine in striatum and nucleus accumbens. Journal of Neurochemistry. 67: 2292-9. PMID 8931460 DOI: 10.1046/J.1471-4159.1996.67062292.X  0.55
1996 Garrett BE, Holtzman SG. Comparison of the effects of prototypical behavioral stimulants on locomotor activity and rotational behavior in rats. Pharmacology, Biochemistry, and Behavior. 54: 469-77. PMID 8743610 DOI: 10.1016/0091-3057(95)02209-0  0.471
1996 Holtzman SG. Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, in monkeys: comparison to methylxanthines. The Journal of Pharmacology and Experimental Therapeutics. 277: 739-46. PMID 8627553  0.306
1995 Garrett BE, Holtzman SG. The effects of dopamine agonists on rotational behavior in non-tolerant and caffeine-tolerant rats. Behavioural Pharmacology. 6: 843-851. PMID 11224389  0.369
1995 Kimmel HL, Garrett BE, Holtzman SG. Effects of acute and chronic morphine on rotational behavior in nigral-lesioned rats. Pharmacology, Biochemistry, and Behavior. 52: 397-401. PMID 8577807 DOI: 10.1016/0091-3057(95)00125-G  0.777
1995 Schad CA, Justice JB, Holtzman SG. Naloxone reduces the neurochemical and behavioral effects of amphetamine but not those of cocaine. European Journal of Pharmacology. 275: 9-16. PMID 7774666 DOI: 10.1016/0014-2999(94)00726-N  0.521
1995 Woolfolk DR, Holtzman SG. Rat strain differences in the potentiation of morphine-induced analgesia by stress. Pharmacology, Biochemistry, and Behavior. 51: 699-703. PMID 7675846 DOI: 10.1016/0091-3057(94)00440-T  0.549
1995 Garrett BE, Holtzman SG. Does adenosine receptor blockade mediate caffeine-induced rotational behavior? The Journal of Pharmacology and Experimental Therapeutics. 274: 207-14. PMID 7616401  0.333
1994 Holtzman SG, Steinfels GF. Monoamine systems in the discriminative effects of spiradoline, a kappa-opioid agonist. Pharmacology, Biochemistry, and Behavior. 47: 575-8. PMID 8208776 DOI: 10.1016/0091-3057(94)90161-9  0.537
1994 White-Gbadebo D, Holtzman SG. Acute sensitization to opioid antagonists. Pharmacology, Biochemistry, and Behavior. 47: 559-66. PMID 8208774 DOI: 10.1016/0091-3057(94)90159-7  0.649
1994 Holtzman SG, Steinfels GF, Schmidt WK. Assessing spiradoline-like discriminative effects of DuP 747: influence of route of administration. Pharmacology, Biochemistry, and Behavior. 47: 487-91. PMID 8208766 DOI: 10.1016/0091-3057(94)90148-1  0.566
1994 Jones DN, Holtzman SG. Behavioral effects of systemically administered mu and kappa opioid agonists in the squirrel monkey: peptides versus alkaloids. Pharmacology, Biochemistry, and Behavior. 47: 421-6. PMID 7911572 DOI: 10.1016/0091-3057(94)90138-4  0.58
1994 Garrett BE, Holtzman SG. D1 and D2 dopamine receptor antagonists block caffeine-induced stimulation of locomotor activity in rats. Pharmacology, Biochemistry, and Behavior. 47: 89-94. PMID 7906891 DOI: 10.1016/0091-3057(94)90115-5  0.426
1994 Holtzman SG. Discriminative stimulus effects of dextromethorphan in the rat. Psychopharmacology. 116: 249-54. PMID 7892413 DOI: 10.1007/BF02245325  0.541
1994 Holtzman SG, Steinfels GF. Antagonism of the discriminative stimulus effects of the kappa-opioid agonist spiradoline. Psychopharmacology. 116: 243-8. PMID 7892412 DOI: 10.1007/BF02245324  0.604
1994 Hooks MS, Jones DN, Holtzman SG, Juncos JL, Kalivas PW, Justice JB. Individual differences in behavior following amphetamine, GBR-12909, or apomorphine but not SKF-38393 or quinpirole. Psychopharmacology. 116: 217-25. PMID 7862951 DOI: 10.1007/Bf02245065  0.474
1994 Paronis CA, Holtzman SG. Sensitization and tolerance to the discriminative stimulus effects of mu-opioid agonists. Psychopharmacology. 114: 601-10. PMID 7855222 DOI: 10.1007/BF02244991  0.637
1994 White-Gbadebo D, Holtzman S. Naloxone pretreatment blocks acute morphine-induced sensitization to naltrexone Psychopharmacology. 114: 225-228. PMID 7838911 DOI: 10.1007/BF02244840  0.643
1994 Jones DN, Holtzman SG. Influence of naloxone upon motor activity induced by psychomotor stimulant drugs. Psychopharmacology. 114: 215-24. PMID 7838910 DOI: 10.1007/BF02244839  0.504
1994 Garrett BE, Holtzman SG. Caffeine cross-tolerance to selective dopamine D1 and D2 receptor agonists but not to their synergistic interaction. European Journal of Pharmacology. 262: 65-75. PMID 7813580 DOI: 10.1016/0014-2999(94)90029-9  0.432
1993 Holtzman SG. Discriminative stimulus effects of the PCP/sigma-ligand (+)-N-allylnormetazocine in monkeys. Pharmacology, Biochemistry, and Behavior. 44: 349-55. PMID 8446667 DOI: 10.1016/0091-3057(93)90473-7  0.558
1993 Levesque D, Holtzman SG. The potentiating effects of restraint stress and continuous naloxone infusion on the analgesic potency or morphine are additive. Brain Research. 617: 176-80. PMID 8374741 DOI: 10.1016/0006-8993(93)90633-X  0.643
1993 Paronis CA, Waddell AB, Holtzman SG. Naltrexone in vivo protects mu receptors from inactivation by beta-funaltrexamine, but not kappa receptors from inactivation by nor-binaltorphimine. Pharmacology, Biochemistry, and Behavior. 46: 813-7. PMID 8309960 DOI: 10.1016/0091-3057(93)90206-9  0.552
1993 Jones DN, Bowen WD, Portoghese PS, Holtzman SG. Delta-opioid receptor antagonists attenuate motor activity induced by amphetamine but not cocaine. European Journal of Pharmacology. 249: 167-77. PMID 8287898 DOI: 10.1016/0014-2999(93)90429-L  0.583
1993 Woolfolk DR, Holtzman SG. Restraint stress potentiates analgesia induced by 5'-N-ethylcarboxamidoadenosine: comparison with morphine. European Journal of Pharmacology. 239: 177-82. PMID 8223892 DOI: 10.1016/0014-2999(93)90991-P  0.608
1992 Paronis CA, Holtzman SG. Development of tolerance to the analgesic activity of mu agonists after continuous infusion of morphine, meperidine or fentanyl in rats. The Journal of Pharmacology and Experimental Therapeutics. 262: 1-9. PMID 1625189  0.568
1992 Calcagnetti DJ, Holtzman SG. Potentiation of morphine analgesia in rats given a single exposure to restraint stress immobilization. Pharmacology, Biochemistry, and Behavior. 41: 449-53. PMID 1574536 DOI: 10.1016/0091-3057(92)90125-Y  0.619
1992 Paronis CA, Holtzman SG. Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone. Life Sciences. 50: 1407-16. PMID 1573974 DOI: 10.1016/0024-3205(92)90259-R  0.653
1992 Hooks MS, Jones DN, Justice JB, Holtzman SG. Naloxone reduces amphetamine-induced stimulation of locomotor activity and in vivo dopamine release in the striatum and nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 42: 765-70. PMID 1513859 DOI: 10.1016/0091-3057(92)90027-D  0.539
1992 Calcagnetti DJ, Holtzman SG. Intake of sweet water attenuates restraint-stress-induced potentiation of morphine analgesia in rats. Brain Research Bulletin. 29: 859-64. PMID 1473017 DOI: 10.1016/0361-9230(92)90156-R  0.518
1992 Jones DN, Holtzman SG. Effects of naloxone infusion upon spontaneous and amphetamine-induced activity. European Journal of Pharmacology. 221: 161-5. PMID 1333971 DOI: 10.1016/0014-2999(92)90787-5  0.47
1992 Jones DN, Holtzman SG. Long term kappa-opioid receptor blockade following nor-binaltorphimine. European Journal of Pharmacology. 215: 345-8. PMID 1327807 DOI: 10.1016/0014-2999(92)90055-9  0.596
1992 Jones DN, Holtzman SG. Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. 262: 638-45. PMID 1323656  0.497
1991 Holtzman SG, Young CW. Motor activity of squirrel monkeys measured with an ultrasonic motion sensor. Pharmacology, Biochemistry, and Behavior. 38: 633-7. PMID 2068200 DOI: 10.1016/0091-3057(91)90025-W  0.309
1991 Calcagnetti DJ, Holtzman SG. Delta opioid antagonist, naltrindole, selectively blocks analgesia induced by DPDPE but not DAGO or morphine. Pharmacology, Biochemistry, and Behavior. 38: 185-90. PMID 2017444 DOI: 10.1016/0091-3057(91)90608-5  0.662
1991 Holtzman SG. CGS 15943, a nonxanthine adenosine receptor antagonist: effects on locomotor activity of nontolerant and caffeine-tolerant rats. Life Sciences. 49: 1563-70. PMID 1943461 DOI: 10.1016/0024-3205(91)90329-A  0.493
1991 Mumford GK, Holtzman SG. Qualitative differences in the discriminative stimulus effects of low and high doses of caffeine in the rat. The Journal of Pharmacology and Experimental Therapeutics. 258: 857-65. PMID 1890622  0.38
1991 Mumford GK, Holtzman SG. Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat? Brain Research. 550: 172-8. PMID 1888997 DOI: 10.1016/0006-8993(91)90425-U  0.394
1991 Holtzman SG, Mante S, Minneman KP. Role of adenosine receptors in caffeine tolerance. The Journal of Pharmacology and Experimental Therapeutics. 256: 62-8. PMID 1846425  0.361
1991 Adams JU, Holtzman SG. Naltrexone-sensitizing effects of centrally administered morphine and opioid peptides. European Journal of Pharmacology. 193: 67-73. PMID 1675608 DOI: 10.1016/0014-2999(91)90201-Z  0.607
1991 Adams JU, Holtzman SG. Effects of receptor-selective opioids on operant behavior in morphine-treated and untreated rats. Pharmacology, Biochemistry, and Behavior. 38: 195-200. PMID 1673249 DOI: 10.1016/0091-3057(91)90610-E  0.639
1991 Holtzman SG, Cook L, Steinfels GF. Discriminative stimulus effects of spiradoline, a kappa-opioid agonist. Psychopharmacology. 105: 447-52. PMID 1663252 DOI: 10.1007/BF02244362  0.651
1991 Paronis CA, Holtzman SG. Increased analgesic potency of mu agonists after continuous naloxone infusion in rats. The Journal of Pharmacology and Experimental Therapeutics. 259: 582-9. PMID 1658305  0.604
1990 Adams JU, Holtzman SG. Pharmacologic characterization of the sensitization to the rate-decreasing effects of naltrexone induced by acute opioid pretreatment in rats. The Journal of Pharmacology and Experimental Therapeutics. 253: 483-9. PMID 2338644  0.572
1990 Adams JU, Holtzman SG. Tolerance and dependence after continuous morphine infusion from osmotic pumps measured by operant responding in rats. Psychopharmacology. 100: 451-8. PMID 2320705 DOI: 10.1007/BF02243995  0.638
1990 Mumford GK, Holtzman SG. Methylxanthines elevate reinforcement threshold for electrical brain stimulation: role of adenosine receptors and phosphodiesterase inhibition. Brain Research. 528: 32-8. PMID 2245338 DOI: 10.1016/0006-8993(90)90191-D  0.375
1990 Calcagnetti DJ, Fleetwood SW, Holtzman SG. Pharmacological profile of the potentiation of opioid analgesia by restraint stress. Pharmacology, Biochemistry, and Behavior. 37: 193-9. PMID 2175919 DOI: 10.1016/0091-3057(90)90061-L  0.625
1990 Adams JU, Paronis CA, Holtzman SG. Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine. The Journal of Pharmacology and Experimental Therapeutics. 255: 1027-32. PMID 2175793  0.447
1990 Calcagnetti DJ, Bowen WD, Holtzman SG. Stress-induced tolerance to delta receptor agonist DPDPE and selectivity of the irreversible delta-ligand, DALCE. Brain Research. 509: 205-12. PMID 2157520 DOI: 10.1016/0006-8993(90)90545-M  0.497
1990 Calcagnetti DJ, Holtzman SG. Factors affecting restraint stress-induced potentiation of morphine analgesia. Brain Research. 537: 157-62. PMID 2085771 DOI: 10.1016/0006-8993(90)90352-C  0.624
1990 Finn IB, Iuvone PM, Holtzman SG. Depletion of catecholamines in the brain of rats differentially affects stimulation of locomotor activity by caffeine, D-amphetamine, and methylphenidate. Neuropharmacology. 29: 625-31. PMID 1974712 DOI: 10.1016/0028-3908(90)90023-K  0.481
1989 Fleetwood SW, Holtzman SG. Stress-induced potentiation of morphine-induced analgesia in morphine-tolerant rats. Neuropharmacology. 28: 563-7. PMID 2569174 DOI: 10.1016/0028-3908(89)90134-2  0.634
1989 Holtzman SG. Opioid- and phencyclidine-like discriminative effects of ditolylguanidine, a selective sigma ligand. The Journal of Pharmacology and Experimental Therapeutics. 248: 1054-62. PMID 2539453  0.498
1989 Holtzman SG. Phosphodiesterase inhibitors potentiate opiate-antagonist discrimination by morphine-dependent rats. Pharmacology, Biochemistry, and Behavior. 33: 875-9. PMID 2482511 DOI: 10.1016/0091-3057(89)90485-1  0.63
1988 Finn IB, Holtzman SG. Tolerance and cross-tolerance to theophylline-induced stimulation of locomotor activity in rats. Life Sciences. 42: 2475-82. PMID 3374267 DOI: 10.1016/0024-3205(88)90346-3  0.489
1988 Holtzman SG, Finn IB. Tolerance to behavioral effects of caffeine in rats. Pharmacology, Biochemistry, and Behavior. 29: 411-8. PMID 3362935 DOI: 10.1016/0091-3057(88)90179-7  0.498
1988 Ukai M, Holtzman SG. Restricted feeding does not modify discriminative stimulus effects of morphine in the rat. Pharmacology, Biochemistry, and Behavior. 29: 201-3. PMID 3353426 DOI: 10.1016/0091-3057(88)90297-3  0.607
1988 Mumford GK, Neill DB, Holtzman SG. Caffeine elevates reinforcement threshold for electrical brain stimulation: tolerance and withdrawal changes. Brain Research. 459: 163-7. PMID 3167574 DOI: 10.1016/0006-8993(88)90298-3  0.396
1988 Andrews JS, Holtzman SG. Effects of d-amphetamine, morphine, naloxone, and drug combinations on visual discrimination in rats. Psychopharmacology. 94: 172-7. PMID 3127842 DOI: 10.1007/BF00176840  0.623
1988 Ukai M, Holtzman SG. Effects of intrahypothalamic administration of opioid peptides selective for mu-, kappa, and delta-receptors on different schedules of water intake in the rat. Brain Research. 459: 275-81. PMID 2902901 DOI: 10.1016/0006-8993(88)90643-9  0.56
1988 Ukai M, Holtzman SG. Morphine-like discriminative stimulus effects of opioid peptides: possible modulatory role of D-Ala2-D-Leu5-enkephalin (DADL) and dynorphin A (1-13). Psychopharmacology. 94: 32-7. PMID 2894701 DOI: 10.1007/BF00735877  0.605
1988 Ukai M, Holtzman SG. Effects of beta-funaltrexamine on ingestive behaviors in the rat. European Journal of Pharmacology. 153: 161-5. PMID 2846315 DOI: 10.1016/0014-2999(88)90602-4  0.412
1987 Holtzman SG. Discriminative stimulus effects of caffeine: tolerance and cross-tolerance with methylphenidate. Life Sciences. 40: 381-9. PMID 3807640 DOI: 10.1016/0024-3205(87)90140-8  0.473
1987 Andrews JS, Holtzman SG. Effects of naloxone and diprenorphine on amphetamine-stimulated behavior in guinea pigs and rats. Neuropharmacology. 26: 1115-20. PMID 3658118 DOI: 10.1016/0028-3908(87)90256-5  0.468
1987 Andrews JS, Holtzman SG. The interaction of d-amphetamine and naloxone differs for rats trained on separate fixed-interval or fixed-ratio schedules of reinforcement. Pharmacology, Biochemistry, and Behavior. 26: 167-71. PMID 3562487 DOI: 10.1016/0091-3057(87)90550-8  0.552
1987 Finn IB, Holtzman SG. Pharmacologic specificity of tolerance to caffeine-induced stimulation of locomotor activity. Psychopharmacology. 93: 428-34. PMID 3124175 DOI: 10.1007/BF00207230  0.499
1987 Ukai M, Holtzman SG. Suppression of deprivation-induced water intake in the rat by opioid antagonists: central sites of action. Psychopharmacology. 91: 279-84. PMID 3104950 DOI: 10.1007/BF00518177  0.496
1987 Adams JU, Andrews JS, Hiller JM, Simon EJ, Holtzman SG. Effects of stress and beta-funal trexamine pretreatment on morphine analgesia and opioid binding in rats. Life Sciences. 41: 2835-44. PMID 2826950 DOI: 10.1016/0024-3205(87)90430-9  0.573
1986 Finn IB, Holtzman SG. Tolerance to caffeine-induced stimulation of locomotor activity in rats. The Journal of Pharmacology and Experimental Therapeutics. 238: 542-6. PMID 3735131  0.387
1986 Holtzman SG. Multiple receptor types in opioid discrimination. Nida Research Monograph. 71: 109-26. PMID 3025731  0.381
1986 Locke KW, Holtzman SG. Behavioral effects of opioid peptides selective for mu or delta receptors. II. Locomotor activity in nondependent and morphine-dependent rats. The Journal of Pharmacology and Experimental Therapeutics. 238: 997-1003. PMID 3018231  0.504
1986 Locke KW, Holtzman SG. Behavioral effects of opioid peptides selective for mu or delta receptors. I. Morphine-like discriminative stimulus effects. The Journal of Pharmacology and Experimental Therapeutics. 238: 990-6. PMID 3018230  0.465
1986 Appelbaum BD, Holtzman SG. Stress-induced changes in the analgesic and thermic effects of opioid peptides in the rat. Brain Research. 377: 330-6. PMID 3015351 DOI: 10.1016/0006-8993(86)90876-0  0.581
1986 DeRossett SE, Holtzman SG. Discriminative stimulus effects of the opioid antagonist diprenorphine in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 237: 437-44. PMID 3009783  0.52
1986 Holtzman SG. Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation. The Journal of Pharmacology and Experimental Therapeutics. 239: 706-14. PMID 2432216  0.373
1985 Appelbaum BD, Holtzman SG. Stress-induced changes in the analgesic and thermic effects of morphine administered centrally. Brain Research. 358: 303-8. PMID 4075121 DOI: 10.1016/0006-8993(85)90974-6  0.522
1985 Appelbaum BD, Holtzman SG. Restraint stress has no effect on morphine-induced inhibition of gastrointestinal transit in the rat. Physiology & Behavior. 34: 995-7. PMID 4059389 DOI: 10.1016/0031-9384(85)90026-5  0.584
1985 Holtzman SG. Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs. The Journal of Pharmacology and Experimental Therapeutics. 233: 80-6. PMID 4039002  0.552
1985 Locke KW, Holtzman SG. Characterization of the discriminative stimulus effects of centrally administered morphine in the rat. Psychopharmacology. 87: 1-6. PMID 2997824 DOI: 10.1007/BF00431767  0.633
1985 DeRossett SE, Holtzman SG. Effects of opiate antagonists and putative kappa agonists on unpunished and punished operant behavior in the rat. Psychopharmacology. 86: 386-91. PMID 2994149 DOI: 10.1007/BF00427896  0.567
1985 Appelbaum BD, Holtzman SG. Restraint stress enhances morphine-induced analgesia in the rat without changing apparent affinity of receptor. Life Sciences. 36: 1069-74. PMID 2983165 DOI: 10.1016/0024-3205(85)90492-8  0.609
1985 Holtzman SG. Drug discrimination studies. Drug and Alcohol Dependence. 14: 263-82. PMID 2859972 DOI: 10.1016/0376-8716(85)90061-4  0.554
1984 DeRossett SE, Holtzman SG. Effects of naloxone, diprenorphine, buprenorphine and etorphine on unpunished and punished food-reinforced responding in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 228: 669-75. PMID 6707916  0.433
1984 Appelbaum BD, Holtzman SG. Characterization of stress-induced potentiation of opioid effects in the rat. The Journal of Pharmacology and Experimental Therapeutics. 231: 555-65. PMID 6502514  0.525
1984 Herman BH, Holtzman SG. Repeated administration of naltrexone and diprenorphine decreases food intake and body weight in squirrel monkeys. Life Sciences. 34: 1-12. PMID 6319931 DOI: 10.1016/0024-3205(84)90324-2  0.463
1984 Minneman KP, Holtzman SG. Morphine dependence and withdrawal without alterations in cerebral beta-adrenergic receptor density. Biochemical Pharmacology. 33: 2331-3. PMID 6087822 DOI: 10.1016/0006-2952(84)90676-2  0.417
1984 Appelbaum BD, Holtzman SG. Comparison of stress-induced and hypophysectomy-induced potentiation of opioid analgesia in the rat Federation Proceedings. 43: no. 2663.  0.47
1984 Locke KW, Holtzman SG. Effects of receptor-selective opioid peptides on locomotor activity in nondependent and morphine-dependent rats Federation Proceedings. 43: No. 3811.  0.49
1983 Holtzman SG. Complete, reversible, drug-specific tolerance to stimulation of locomotor activity by caffeine. Life Sciences. 33: 779-87. PMID 6888193 DOI: 10.1016/0024-3205(83)90784-1  0.441
1983 White JM, Holtzman SG. The effects of naloxone, diprenorphine, and diazepam on responding suppressed by pre-shock and pre-food stimuli. Life Sciences. 32: 479-86. PMID 6823206 DOI: 10.1016/0024-3205(83)90141-8  0.437
1983 Cooper SJ, Holtzman SG. Patterns of drinking in the rat following the administration of opiate antagonists. Pharmacology, Biochemistry, and Behavior. 19: 505-11. PMID 6634902 DOI: 10.1016/0091-3057(83)90127-2  0.493
1983 White JM, Holtzman SG. Three-choice drug discrimination: phencyclidine-like stimulus effects of opioids. Psychopharmacology. 80: 1-9. PMID 6408661 DOI: 10.1007/BF00427484  0.578
1983 White JM, Holtzman SG. Further characterization of the three-choice morphine, cyclazocine and saline discrimination paradigm: opioids with agonist and antagonist properties. The Journal of Pharmacology and Experimental Therapeutics. 224: 95-9. PMID 6336785  0.533
1982 Brady LS, Holtzman SG. Analgesic effects of intraventricular morphine and enkephalins in nondependent and morphine-dependent rats. The Journal of Pharmacology and Experimental Therapeutics. 222: 190-7. PMID 7201020  0.772
1982 DeRossett SE, Holtzman SG. Effects of naloxone and diprenorphine on spontaneous activity in rats and mice. Pharmacology, Biochemistry, and Behavior. 17: 347-51. PMID 7134243 DOI: 10.1016/0091-3057(82)90090-9  0.565
1982 White JM, Holtzman SG. Properties of pentazocine as a discriminative stimulus in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 223: 396-401. PMID 7131294  0.462
1982 Kirby ML, Holtzman SG. Effects of chronic opiate administration on spontaneous activity of fetal rats Pharmacology, Biochemistry and Behavior. 16: 263-269. PMID 7071079 DOI: 10.1016/0091-3057(82)90159-9  0.614
1982 Holtzman SG. Phencyclidine-like discriminative stimulus properties of opioids in the squirrel monkey. Psychopharmacology. 77: 295-300. PMID 6813889 DOI: 10.1007/Bf00432758  0.575
1982 Holtzman SG. Phencyclidine-like discriminative stimulus properties of psychotomimetic opioids. Annals of the New York Academy of Sciences. 398: 230-40. PMID 6760769 DOI: 10.1111/J.1749-6632.1982.Tb39497.X  0.505
1982 Locke KW, Brown DR, Holtzman SG. Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey. Pharmacology, Biochemistry, and Behavior. 17: 1275-9. PMID 6298835 DOI: 10.1016/0091-3057(82)90133-2  0.586
1982 Kirby ML, DeRossett SE, Holtzman SG. Enhanced analgesic response to morphine in adult rats exposed to morphine prenatally. Pharmacology, Biochemistry, and Behavior. 17: 1161-4. PMID 6298830 DOI: 10.1016/0091-3057(82)90113-7  0.638
1982 Holtzman SG. Stimulus properties of opioids with mixed agonist and antagonist activity. Federation Proceedings. 41: 2328-32. PMID 6281084  0.49
1982 Holtzman SG. Discriminative stimulus properties of opioids in the rat and squirrel monkey Psychopharmacology. 76: No. 20.  0.475
1981 Brown DR, Holtzman SG. Suppression of drinking by naloxone in rats homo- and heterozygous for diabetes insipidus. Pharmacology, Biochemistry, and Behavior. 15: 109-14. PMID 7291218 DOI: 10.1016/0091-3057(81)90347-6  0.608
1981 Brown DR, Holtzman SG. Opiate antagonists: central sites of action in suppressing water intake of the rat. Brain Research. 221: 432-6. PMID 7284781 DOI: 10.1016/0006-8993(81)90796-4  0.507
1981 Brown DR, Holtzman SG. Narcotic antagonists attenuate drinking induced by water deprivation in a primate. Life Sciences. 28: 1287-94. PMID 7231051 DOI: 10.1016/0024-3205(81)90455-0  0.546
1981 White JM, Holtzman SG. Three-choice drug discrimination in the rat: morphine, cyclazocine and saline. The Journal of Pharmacology and Experimental Therapeutics. 217: 254-62. PMID 7229971  0.458
1981 Brown DR, Holtzman SG. Suppression of drinking by naloxone in the rat: a further characterization. European Journal of Pharmacology. 69: 331-40. PMID 7215432 DOI: 10.1016/0014-2999(81)90479-9  0.494
1981 Brady LS, Holtzman SG. Effects of intraventricular morphine and enkephalins on schedule-controlled behavior in nondependent, morphine-dependent and postdependent rats. The Journal of Pharmacology and Experimental Therapeutics. 219: 344-51. PMID 7197301  0.772
1981 Brady LS, Holtzman SG. Locomotor activity in morphine-dependent and post-dependent rats. Pharmacology, Biochemistry, and Behavior. 14: 361-70. PMID 7195032 DOI: 10.1016/0091-3057(81)90403-2  0.779
1981 Brady LS, Holtzman SG. Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats. The Journal of Pharmacology and Experimental Therapeutics. 218: 613-20. PMID 7021799  0.763
1981 Schaefer GJ, Holtzman SG. Morphine-like stimulus effects in the monkey: opioids with antagonist properties. Pharmacology, Biochemistry, and Behavior. 14: 241-5. PMID 6451874 DOI: 10.1016/0091-3057(81)90250-1  0.592
1981 Holtzman SG. Suppression of the discriminative effects of morphine (M) withdrawal in the dependent rat Federation Proceedings. 40: 56.  0.468
1981 Brady LS, Holtzman SG. Effects of intraventricular (IVT) morphine and enkephalins on schedule-controlled responding in morphine-dependent and non-dependent rats Federation Proceedings. 40: 411.  0.758
1980 Teal JJ, Holtzman SG. Stereoselectivity of the stimulus effects of morphine and cyclazocine in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 215: 369-76. PMID 7441501  0.429
1980 Brown DR, Blank MS, Holtzman SG. Suppression by naloxone of water intake induced by deprivation and hypertonic saline in intact and hypophysectomized rats. Life Sciences. 26: 1535-42. PMID 7392802 DOI: 10.1016/0024-3205(80)90277-5  0.454
1980 Brady LS, Holtzman SG. Schedule-controlled behavior in the morphine-dependent and post-dependent rat. Psychopharmacology. 70: 11-8. PMID 6775328 DOI: 10.1007/BF00432364  0.797
1980 Teal JJ, Holtzman SG. Stimulus effects of morphine in the monkey: quantitative analysis of antagonism. Pharmacology, Biochemistry, and Behavior. 12: 587-93. PMID 6771774 DOI: 10.1016/0091-3057(80)90193-8  0.62
1980 Teal JJ, Holtzman SG. Discriminative stimulus effects of prototype opiate receptor agonists in monkeys. European Journal of Pharmacology. 68: 1-10. PMID 6256182 DOI: 10.1016/0014-2999(80)90053-9  0.564
1980 Brown DR, Holtzman SG. Evidence that opiate receptors mediate suppression of hypertonic saline-induced drinking in the mouse by narcotic antagonists. Life Sciences. 26: 1543-50. PMID 6248713 DOI: 10.1016/0024-3205(80)90278-7  0.508
1980 Holtzman SG. Phencyclidine-like discriminative effects of opioids in the rat. The Journal of Pharmacology and Experimental Therapeutics. 214: 614-9. PMID 6105206  0.49
1980 White JM, Holtzman SG. Concurrent discrimination of morphine (M), cyclazocine (C) and saline (S) in the rat Federation Proceedings. 39: 3823.  0.383
1980 Holtzman SG. Phencyclidine (PCP)-like discriminative effects of opioids in the rat Federation Proceedings. 39: 3822.  0.533
1980 Brown DR, Holtzman SG. Suppression of drinking by pure opiate antagonists in rats and monkeys Federation Proceedings. 39: 3825.  0.378
1979 Gellert VF, Holtzman SG. Discriminative stimulus effects of naltrexone in the morphine-dependent rat. The Journal of Pharmacology and Experimental Therapeutics. 211: 596-605. PMID 574545  0.589
1979 Holtzman SG. Suppression of appetitive behavior in the rat by naloxone: lack of effect of prior morphine dependence. Life Sciences. 24: 219-26. PMID 570626 DOI: 10.1016/0024-3205(79)90222-4  0.639
1979 Brown DR, Holtzman SG. Suppression of deprivation-induced food and water intake in rats and mice by naloxone. Pharmacology, Biochemistry, and Behavior. 11: 567-73. PMID 531080 DOI: 10.1016/0091-3057(79)90043-1  0.455
1979 Holtzman SG. Discriminative stimulus properties of levo-alpha-acetylmethadol and its metabolites. Pharmacology, Biochemistry, and Behavior. 10: 565-8. PMID 461484 DOI: 10.1016/0091-3057(79)90234-X  0.414
1979 Schaefer GJ, Holtzman SG. Free-operant and auto-titration brain self-stimulation procedures in the rat: a comparison of drug effects. Pharmacology, Biochemistry, and Behavior. 10: 127-35. PMID 441089 DOI: 10.1016/0091-3057(79)90178-3  0.361
1979 Shannon HE, Holtzman SG. Morphine training dose: a determinant of stimulus generalization to narcotic antagonists in the rat. Psychopharmacology. 61: 239-44. PMID 156379 DOI: 10.1007/BF00432265  0.585
1979 Holtzman SG. Failure of naloxone to modify the effects of chlorpromazine and d-amphetamine on avoidance behavior in the squirrel monkey. Psychopharmacology. 63: 207-9. PMID 113805 DOI: 10.1007/BF00433551  0.469
1979 Brady LS, Holtzman SG. Locomotor activity (LA) in morphine (M) tolerant and nontolerant rats Federation Proceedings. 38: No. 1899.  0.692
1979 Brown DR, Holtzman SG. Effects of naloxone on appetitive behavior in rats and mice Federation Proceedings. 38: No. 3300.  0.311
1978 Gellert VF, Holtzman SG. Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions. The Journal of Pharmacology and Experimental Therapeutics. 205: 536-46. PMID 566320  0.504
1978 Schaefer GJ, Holtzman SG. Discriminative effects of cyclazocine in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 205: 291-301. PMID 417173  0.383
1977 Shannon HE, Holtzman SG. Discriminative effects of morphine administered intracerebrally in the rat. Life Sciences. 21: 585-94. PMID 904437 DOI: 10.1016/0024-3205(77)90101-1  0.616
1977 Holtzman SG, Shannon E, Schaefer GJ. Discriminative effects of narcotic agonists and antagonists in the rat and squirrel monkey [proceedings]. Psychopharmacology Bulletin. 13: 37-8. PMID 402009  0.426
1977 Schaefer GJ, Holtzman SG. Dose- and time-dependent effects of narcotic analgesics on intracranial self-stimulation in the rat. Psychopharmacology. 53: 227-34. PMID 19804 DOI: 10.1007/Bf00492356  0.59
1977 Shannon HE, Holtzman SG. Further evaluation of the discriminative effects of morphine in the rat. The Journal of Pharmacology and Experimental Therapeutics. 201: 55-66. PMID 15104  0.47
1977 O'Callaghan JP, Holtzman SG. Prenatal administration of levorphanol or dextrorphan to the rat: analgesic effect of morphine in the offspring. The Journal of Pharmacology and Experimental Therapeutics. 200: 255-62. PMID 14248  0.549
1976 Shannon HE, Holtzman SG. Blockade of the specific lethal effects of narcotic analgesics in the mouse. European Journal of Pharmacology. 39: 295-303. PMID 976325 DOI: 10.1016/0014-2999(76)90139-4  0.581
1976 Holtzman SG. Comparison of the effects of morphine, pentazocine, cyclazocine and amphetamine on intracranial self-stimulation in the rat. Psychopharmacologia. 46: 223-7. PMID 951457 DOI: 10.1007/Bf00421106  0.56
1976 O'Callaghan JP, Holtzman SG. Prenatal administration of morphine to the rat: tolerance to the analgesic effect of morphine in the offspring. The Journal of Pharmacology and Experimental Therapeutics. 197: 533-44. PMID 932990  0.57
1976 Shannon HE, Holtzman SG. Blockade of the discriminative effects of morphine in the rat by naltrexone and naloxone. Psychopharmacology. 50: 119-24. PMID 826950 DOI: 10.1007/Bf00430479  0.654
1976 Holtzman SG, Shannon HE, Schaefer GJ. Discriminative properties of narcotic antagonists. Psychopharmacology Communications. 2: 315-8. PMID 825930 DOI: 10.1007/978-1-4684-3090-5_4  0.404
1976 Holtzman SG. Effects of morphine and narcotic antagonists on avoidance behavior of the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 196: 145-55. PMID 812979  0.459
1976 Shannon HE, Holtzman SG, Davis DC. Interactions between narcotic analgesics and benzodiazepine derivatives on behavior in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 199: 389-99. PMID 10428  0.482
1976 Shannon HE, Holtzman SG. Evaluation of the discriminative effects of morphine in the rat. The Journal of Pharmacology and Experimental Therapeutics. 198: 54-65. PMID 6794  0.47
1976 Sung YF, Holtzman SG. Effects of intravenous anesthetics on continuous avoidance behavior in the rat. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 219: 243-50. PMID 5976  0.303
1975 Holtzman SG. Effects of narcotic antagonists on fluid intake in the rat. Life Sciences. 16: 1465-70. PMID 1134204 DOI: 10.1016/0024-3205(75)90043-0  0.459
1974 Holtzman SG. Behavioral effects of separate and combined administration of naloxone and d-amphetamine. The Journal of Pharmacology and Experimental Therapeutics. 189: 51-60. PMID 4823299  0.311
1974 Holtzman SG. Behavioral effects of profadol in the rat. Psychopharmacologia. 34: 135-42. PMID 4818022 DOI: 10.1007/Bf00421938  0.613
1974 Holtzman SG. Interactions of pentazocine and naloxone on the monoamine content of discrete regions of the rat brain. Biochemical Pharmacology. 23: 3029-35. PMID 4429600 DOI: 10.1016/0006-2952(74)90278-0  0.471
1974 Holtzman SG. Tolerance to the stimulant effects of morphine and pentazocine on avoidance responding in the rat. Psychopharmacologia. 39: 23-37. PMID 4423602 DOI: 10.1007/Bf00421455  0.64
1973 Holtzman SG. Narcotic antagonists as stimulants of behavior in the rat: specific and nonspecific effects. Advances in Biochemical Psychopharmacology. 8: 371-82. PMID 4794990  0.319
1973 Holtzman SG, Jewett RE. Stimulation of behavior in the rat by cyclazocine: effects of naloxone. The Journal of Pharmacology and Experimental Therapeutics. 187: 380-90. PMID 4748554  0.346
1973 Steinert HR, Holtzman SG, Jewett RE. Some agonistic actions of the morphone antagonist levallorphan on behavior and brain monoamines in the rat. Psychopharmacologia. 31: 35-48. PMID 4721474 DOI: 10.1007/BF00429297  0.5
1973 Holtzman SG, Villarreal JE. Operant behavior in the morphine-dependent rhesus monkey. The Journal of Pharmacology and Experimental Therapeutics. 184: 528-41. PMID 4631467  0.346
1971 Holtzman SG, Jewett RE. Interactions of morphine and nalorphine with physostigmine on operant behavior in the rat. Psychopharmacologia. 22: 384-95. PMID 5133439 DOI: 10.1007/BF00406876  0.541
1971 Holtzman SG, Jewett RE. The role of brain norepinephrine in the anorexic effects of dextroamphetamine and monoamine oxidase inhibitors in the rat. Psychopharmacologia. 22: 151-61. PMID 5124188 DOI: 10.1007/BF00403623  0.362
1971 Holtzman SG, Villarreal JE. Pharmacologic analysis of the hypothermic responses of the morphine-dependent rhesus monkey. The Journal of Pharmacology and Experimental Therapeutics. 177: 317-25. PMID 4998695  0.441
1969 Holtzman SG, Villarreal JE. Morphine dependence and body temperature in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 166: 125-33. PMID 4975673  0.324
1969 Holtzman SG, Villarreal JE. The effects of morphine on conditioned suppression in rhesus monkeys Psychonomic Science. 17: 161-162. DOI: 10.3758/BF03336496  0.404
Show low-probability matches.