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Hideaki Yano, Ph.D. - Publications

Affiliations: 
Pharmacology and Molecular Signaling Columbia University, New York, NY 
Area:
G-protein coupled receptors and neurotransmitter transporters
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pavletić P, Semeano A, Yano H, Bonifazi A, Giorgioni G, Piergentili A, Quaglia W, Sabbieti MG, Agas D, Santoni G, Pallini R, Ricci-Vitiani L, Sabato E, Vistoli G, Del Bello F. Highly Potent and Selective Dopamine D Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma. Journal of Medicinal Chemistry. 65: 12124-12139. PMID 36098685 DOI: 10.1021/acs.jmedchem.2c00840  0.318
2021 Adhikari P, Xie B, Semeano A, Bonifazi A, Battiti FO, Newman AH, Yano H, Shi L. Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor. Biomolecules. 11. PMID 33924613 DOI: 10.3390/biom11040570  0.362
2020 Yano H, Adhikari P, Naing S, Hoffman AF, Baumann MH, Lupica CR, Shi L. Positive allosteric modulation of the 5-HT receptor by indole-based synthetic cannabinoids abused by humans. Acs Chemical Neuroscience. PMID 32324370 DOI: 10.1021/Acschemneuro.0C00034  0.393
2020 Abramyan AM, Yano H, Xu M, Liu L, Naing S, Fant AD, Shi L. The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor. Computational and Structural Biotechnology Journal. 18: 199-206. PMID 32055286 DOI: 10.1016/J.Csbj.2019.12.012  0.323
2020 Sanchez-Soto M, Verma RK, Willette BKA, Gonye EC, Moore AM, Moritz AE, Boateng CA, Yano H, Free RB, Shi L, Sibley DR. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13. PMID 32019899 DOI: 10.1126/Scisignal.Aaw5885  0.422
2020 Lane JR, Abramyan AM, Adhikari P, Keen AC, Lee KH, Sanchez J, Verma RK, Lim HD, Yano H, Javitch JA, Shi L. Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism. Elife. 9. PMID 31985399 DOI: 10.7554/Elife.52189  0.604
2020 Köfalvi A, Moreno E, Cordomí A, Cai NS, Fernández-Dueñas V, Ferreira SG, Guixà-González R, Sánchez-Soto M, Yano H, Casadó-Anguera V, Cunha RA, Sebastião AM, Ciruela F, Pardo L, Casadó V, et al. Control of glutamate release by complexes of adenosine and cannabinoid receptors. Bmc Biology. 18: 9. PMID 31973708 DOI: 10.1186/S12915-020-0739-0  0.395
2020 Lane JR, Abramyan AM, Adhikari P, Keen AC, Lee K, Sanchez J, Verma RK, Lim HD, Yano H, Javitch JA, Shi L. Author response: Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism Elife. DOI: 10.7554/Elife.52189.Sa2  0.59
2020 Adhikari P, Yano H, Bonifazi A, Battiti FO, Newman AH, Shi L. Chirality of novel bitopic agonists determine unique pharmacology at the dopamine 2 and 3 receptors The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02377  0.46
2019 Yano H, Liu L, Naing S, Shi L. The Effects of Terminal Tagging on Homomeric Interactions of the Sigma 1 Receptor. Frontiers in Neuroscience. 13: 1356. PMID 31920515 DOI: 10.3389/Fnins.2019.01356  0.362
2019 Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SKK, Newman AH, Shi L. A novel Bromine-containing paroxetine analog provides mechanistic clues for binding ambiguity at the central primary binding site of the serotonin transporter. Acs Chemical Neuroscience. PMID 31424193 DOI: 10.1021/Acschemneuro.9B00375  0.332
2019 Francis TC, Yano H, Demarest TG, Shen H, Bonci A. High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs. Neuron. PMID 31221559 DOI: 10.1016/J.Neuron.2019.05.031  0.421
2019 Bonifazi A, Yano H, Guerrero AM, Kumar V, Hoffman AF, Lupica CR, Shi L, Newman AH. Novel and Potent Dopamine D Receptor Go-Protein Biased Agonists. Acs Pharmacology & Translational Science. 2: 52-65. PMID 30775693 DOI: 10.1021/acsptsci.8b00060  0.421
2019 Yano H, Abramyan AM, Naing S, Liu L, Shi L. Mechanistic Characterization of the E102Q Mutation in the Sigma 1 Receptor Biophysical Journal. 116: 533a. DOI: 10.1016/J.Bpj.2018.11.2868  0.312
2018 Sánchez-Soto M, Yano H, Cai NS, Casadó-Anguera V, Moreno E, Casadó V, Ferré S. Revisiting the Functional Role of Dopamine D Receptor Gene Polymorphisms: Heteromerization-Dependent Gain of Function of the D Receptor Variant. Molecular Neurobiology. PMID 30387076 DOI: 10.1007/S12035-018-1413-1  0.367
2018 Yano H, Cai NS, Javitch JA, Ferré S. Luciferase complementation based-detection of G-protein-coupled receptor activity. Biotechniques. 65: 9-14. PMID 30014734 DOI: 10.2144/Btn-2018-0039  0.536
2018 Del Bello F, Bonifazi A, Giorgioni G, Cifani C, Micioni Di Bonaventura MV, Petrelli R, Piergentili A, Fontana S, Mammoli V, Yano H, Matucci R, Vistoli G, Quaglia W. 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor. Journal of Medicinal Chemistry. PMID 29589445 DOI: 10.1021/Acs.Jmedchem.8B00265  0.388
2018 Sánchez-Soto M, Casadó-Anguera V, Yano H, Bender BJ, Cai NS, Moreno E, Canela EI, Cortés A, Meiler J, Casadó V, Ferré S. α- and α-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands. Molecular Neurobiology. PMID 29552726 DOI: 10.1007/S12035-018-1004-1  0.427
2018 Yano H, Bonifazi A, Xu M, Guthrie DA, Schneck SN, Abramyan AM, Fant AD, Hong WC, Newman AH, Shi L. Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays. Neuropharmacology. PMID 29407216 DOI: 10.1016/J.Neuropharm.2018.01.042  0.391
2018 Yano H, Cai NS, Xu M, Verma RK, Rea W, Hoffman AF, Shi L, Javitch JA, Bonci A, Ferré S. Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor. Nature Communications. 9: 486. PMID 29402888 DOI: 10.1038/S41467-017-02606-W  0.625
2017 Yano H, Sánchez-Soto M, Ferré S. Bioluminescence Resonance Energy Transfer Assay to Characterize Gi-Like G Protein Subtype-Dependent Functional Selectivity. Current Protocols in Neuroscience. 81: 5.33.1-5.33.13. PMID 29058771 DOI: 10.1002/Cpns.38  0.34
2017 Yano H, Provasi D, Cai NS, Filizola M, Ferre S, Javitch JA. Development of novel biosensors to study receptor-mediated activation of Gs and Golf. The Journal of Biological Chemistry. PMID 29042444 DOI: 10.1074/Jbc.M117.800698  0.614
2017 Hong WC, Yano H, Hiranita T, Chin FT, McCurdy CR, Su TP, Amara SG, Katz JL. The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats. The Journal of Biological Chemistry. PMID 28495886 DOI: 10.1074/Jbc.M116.774075  0.415
2017 Bonifazi A, Yano H, Ellenberger MP, Muller L, Kumar V, Zou MF, Cai NS, Guerrero AM, Woods AS, Shi L, Newman AH. Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism. Journal of Medicinal Chemistry. PMID 28300398 DOI: 10.1021/Acs.Jmedchem.6B01875  0.432
2016 Michino M, Boateng CA, Donthamsetti P, Yano H, Bakare OM, Bonifazi A, Ellenberger MP, Keck TM, Kumar V, Zhu C, Verma R, Deschamps JR, Javitch JA, Newman AH, Shi L. Towards understanding the structural basis of partial agonism at the dopamine D3 receptor. Journal of Medicinal Chemistry. PMID 27983845 DOI: 10.1021/Acs.Jmedchem.6B01148  0.616
2016 Cao J, Slack RD, Bakare OM, Burzynski C, Rais R, Slusher BS, Kopajtic T, Bonifazi A, Ellenberger MP, Yano H, He Y, Bi GH, Xi ZX, Loland CJ, Newman AH. Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors. Journal of Medicinal Chemistry. 59: 10676-10691. PMID 27933960 DOI: 10.1021/Acs.Jmedchem.6B01373  0.37
2016 Sanchez-Soto M, Bonifazi A, Cai NS, Ellenberger MP, Newman AH, Ferre S, Yano H. Evidence for Non-Canonical Neurotransmitter Activation: Norepinephrine as a Dopamine D2-like Receptor Agonist. Molecular Pharmacology. PMID 26843180 DOI: 10.1124/Mol.115.101808  0.505
2015 Frederick AL, Yano H, Trifilieff P, Vishwasrao HD, Biezonski D, Mészáros J, Urizar E, Sibley DR, Kellendonk C, Sonntag KC, Graham DL, Colbran RJ, Stanwood GD, Javitch JA. Evidence against dopamine D1/D2 receptor heteromers. Molecular Psychiatry. PMID 25560761 DOI: 10.1038/Mp.2014.166  0.604
2014 Malinauskaite L, Quick M, Reinhard L, Lyons JA, Yano H, Javitch JA, Nissen P. A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters. Nature Structural & Molecular Biology. 21: 1006-12. PMID 25282149 DOI: 10.1038/Nsmb.2894  0.519
2014 Bonifazi A, Yano H, Del Bello F, Farande A, Quaglia W, Petrelli R, Matucci R, Nesi M, Vistoli G, Ferré S, Piergentili A. Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1). Journal of Medicinal Chemistry. 57: 9065-77. PMID 25275964 DOI: 10.1021/Jm501173Q  0.316
2014 Gaskill PJ, Yano HH, Kalpana GV, Javitch JA, Berman JW. Dopamine receptor activation increases HIV entry into primary human macrophages. Plos One. 9: e108232. PMID 25268786 DOI: 10.1371/Journal.Pone.0108232  0.518
2014 Guitart X, Navarro G, Moreno E, Yano H, Cai NS, Sánchez-Soto M, Kumar-Barodia S, Naidu YT, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ, Ferré S. Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer. Molecular Pharmacology. 86: 417-29. PMID 25097189 DOI: 10.1124/Mol.114.093096  0.489
2013 Pizzo AB, Karam CS, Zhang Y, Yano H, Freyberg RJ, Karam DS, Freyberg Z, Yamamoto A, McCabe BD, Javitch JA. The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila. Molecular Psychiatry. 18: 824-33. PMID 22710269 DOI: 10.1038/Mp.2012.82  0.672
2013 Yano H, Provasi D, Filizola M, Javitch J. Towards Better Understanding of G(s) Coupling in Catecholamine Receptors Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 89-90. DOI: 10.1016/B978-0-12-800044-1.00076-3  0.492
2011 Urizar E, Yano H, Kolster R, Galés C, Lambert N, Javitch JA. CODA-RET reveals functional selectivity as a result of GPCR heteromerization. Nature Chemical Biology. 7: 624-30. PMID 21785426 DOI: 10.1038/Nchembio.623  0.637
2009 Sohy D, Yano H, de Nadai P, Urizar E, Guillabert A, Javitch JA, Parmentier M, Springael JY. Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists. The Journal of Biological Chemistry. 284: 31270-9. PMID 19758998 DOI: 10.1074/Jbc.M109.054809  0.578
2006 Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum. The Journal of Biological Chemistry. 281: 26444-54. PMID 16798738 DOI: 10.1074/Jbc.M602438200  0.675
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