William A. Eimer, Ph.D. - Publications

Affiliations: 
2013 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Alzheimer's

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kumar DK, Choi SH, Washicosky KJ, Eimer WA, Tucker S, Ghofrani J, Lefkowitz A, McColl G, Goldstein LE, Tanzi RE, Moir RD. Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease. Science Translational Medicine. 8: 340ra72. PMID 27225182 DOI: 10.1126/scitranslmed.aaf1059  0.92
2015 Vijaya Kumar DK, Eimer WA, Ramakrishnan S. Specificity of Toll-Like Receptor 2 and Dectin-1 Signaling in CNS Macrophages. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16015-7. PMID 26658855 DOI: 10.1523/JNEUROSCI.3453-15.2015  0.92
2015 Sadleir KR, Eimer WA, Cole SL, Vassar R. Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level. Molecular Neurodegeneration. 10: 1. PMID 25567526 DOI: 10.1186/1750-1326-10-1  0.92
2014 Sadleir KR, Eimer WA, Kaufman RJ, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. Plos One. 9: e101643. PMID 24992504 DOI: 10.1371/journal.pone.0101643  0.92
2013 Kandalepas PC, Sadleir KR, Eimer WA, Zhao J, Nicholson DA, Vassar R. The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques. Acta Neuropathologica. 126: 329-52. PMID 23820808 DOI: 10.1007/s00401-013-1152-3  0.92
2013 Eimer WA, Vassar R. Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation. Molecular Neurodegeneration. 8: 2. PMID 23316765 DOI: 10.1186/1750-1326-8-2  0.92
2012 Youmans KL, Tai LM, Nwabuisi-Heath E, Jungbauer L, Kanekiyo T, Gan M, Kim J, Eimer WA, Estus S, Rebeck GW, Weeber EJ, Bu G, Yu C, Ladu MJ. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease. The Journal of Biological Chemistry. 287: 41774-86. PMID 23060451 DOI: 10.1074/jbc.M112.407957  0.92
2012 Hitt B, Riordan SM, Kukreja L, Eimer WA, Rajapaksha TW, Vassar R. β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects. The Journal of Biological Chemistry. 287: 38408-25. PMID 22988240 DOI: 10.1074/jbc.M112.415505  0.92
2012 Youmans KL, Tai LM, Kanekiyo T, Stine WB, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ. Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. Molecular Neurodegeneration. 7: 8. PMID 22423893 DOI: 10.1186/1750-1326-7-8  0.92
2011 Rajapaksha TW, Eimer WA, Bozza TC, Vassar R. The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb. Molecular Neurodegeneration. 6: 88. PMID 22204380 DOI: 10.1186/1750-1326-6-88  0.92
2008 O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, et al. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 60: 988-1009. PMID 19109907 DOI: 10.1016/j.neuron.2008.10.047  0.92
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