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Adam S. Crystal, Ph.D. - Publications

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jhaveri K, Juric D, Cresta S, Yap Y, Duhoux FP, Terret C, Layman R, Balbin A, Sheng Q, Liao S, Crystal A, Curigliano G. Abstract P4-10-07: Tumor ER protein modulation, molecular characterization and monitoring of cfDNA in phase 1 study of LSZ102 and LSZ102 + ribociclib in patients with ER+ MBC Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-10-07  0.313
2019 Jhaveri K, Curigliano G, Yap Y, Cresta S, Duhoux F, Terret C, Takahashi S, Ulaner G, Kundamal N, Baldoni D, Liao S, Crystal A, Juric D. Abstract PD1-08: Phase 1/1b study of novel oral selective estrogen receptor degrader (SERD) LSZ102 for estrogen receptor-positive (ER+) advanced breast cancer (ABC) with progression on endocrine therapy (ET) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd1-08  0.306
2019 Curigliano G, Cresta S, Yap Y, Juric D, Duhoux F, Terret C, Takahashi S, Layman R, Kundamal N, Baldoni D, Liao S, Crystal A, Jhaveri K. Abstract OT1-03-01: Phase 1/1b study of novel oral selective estrogen receptor degrader (SERD) LSZ102 in combination with alpelisib (BYL719) in estrogen receptor-positive (ER+), human epidermal growth factor receptor-2–negative (HER2–) advanced breast cancer (ABC) with progression on endocrine therapy (ET) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ot1-03-01  0.334
2019 Gaither LA, Yip CLT, Wang C, Toy W, Sheng Q, Chen J, Mishina Y, Das R, Peukert S, Loo A, Chandarlapaty S, Crystal A, Abrams TJ. Abstract 922: Preclinical anticancer activity of LSZ102, a novel oral selective estrogen receptor degrader targeting wild-type and mutant ER Cancer Research. 79: 922-922. DOI: 10.1158/1538-7445.Am2019-922  0.325
2018 Juric D, Curigliano G, Cresta S, Yap Y, Terret C, Duhoux F, Takahashi S, Kundamal N, Bhansali S, Liao S, Crystal A, Jhaveri K. Abstract P5-21-04: Phase I/Ib study of the SERD LSZ102 alone or in combination with ribociclib in ER+ breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-21-04  0.318
2006 Morais VA, Brito C, Pijak DS, Crystal AS, Fortna RR, Li T, Wong PC, Doms RW, Costa J. N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10. PMID 16938437 DOI: 10.1016/J.Bbadis.2006.06.018  0.408
2004 Crystal AS, Morais VA, Fortna RR, Carlin D, Pierson TC, Wilson CA, Lee VM, Doms RW. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63. PMID 15035625 DOI: 10.1021/Bi0361214  0.571
2004 Fortna RR, Crystal AS, Morais VA, Pijak DS, Lee VM, Doms RW. Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex. The Journal of Biological Chemistry. 279: 3685-93. PMID 14593096 DOI: 10.1074/Jbc.M310505200  0.493
2004 Fortna RR, Schaller N, Morais VA, Crystal AS, Li T, Lee VM, Wong PC, Doms RW. P4-319 Assembly, trafficking, and activity of the gamma-secretase complex Neurobiology of Aging. 25: S566. DOI: 10.1016/S0197-4580(04)81877-3  0.307
2003 Crystal AS, Giasson BI, Crowe A, Kung MP, Zhuang ZP, Trojanowski JQ, Lee VM. A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. Journal of Neurochemistry. 86: 1359-68. PMID 12950445 DOI: 10.1046/J.1471-4159.2003.01949.X  0.531
2003 Morais VA, Crystal AS, Pijak DS, Carlin D, Costa J, Lee VM, Doms RW. The transmembrane domain region of nicastrin mediates direct interactions with APH-1 and the gamma-secretase complex. The Journal of Biological Chemistry. 278: 43284-91. PMID 12917438 DOI: 10.1074/Jbc.M305685200  0.508
2003 Crystal AS, Morais VA, Pierson TC, Pijak DS, Carlin D, Lee VM, Doms RW. Membrane topology of gamma-secretase component PEN-2. The Journal of Biological Chemistry. 278: 20117-23. PMID 12639958 DOI: 10.1074/Jbc.M213107200  0.491
2000 Bertram L, Blacker D, Crystal A, Mullin K, Keeney D, Jones J, Basu S, Yhu S, Guénette S, McInnis M, Go R, Tanzi R. Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies. Experimental Gerontology. 35: 1353-61. PMID 11113613 DOI: 10.1016/S0531-5565(00)00193-5  0.317
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