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John J. Graziotto, Ph.D. - Publications

Affiliations: 
2009 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neural Circuits
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Chung SY, Kishinevsky S, Mazzulli JR, Graziotto J, Mrejeru A, Mosharov EV, Puspita L, Valiulahi P, Sulzer D, Milner TA, Taldone T, Krainc D, Studer L, Shim JW. Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation. Stem Cell Reports. PMID 27641647 DOI: 10.1016/J.Stemcr.2016.08.012  0.375
2012 Cooper O, Seo H, Andrabi S, Guardia-Laguarta C, Graziotto J, Sundberg M, McLean JR, Carrillo-Reid L, Xie Z, Osborn T, Hargus G, Deleidi M, Lawson T, Bogetofte H, Perez-Torres E, et al. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Science Translational Medicine. 4: 141ra90. PMID 22764206 DOI: 10.1126/Scitranslmed.3003985  0.397
2012 Graziotto JJ, Cao K, Collins FS, Krainc D. Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders. Autophagy. 8: 147-51. PMID 22170152 DOI: 10.4161/Auto.8.1.18331  0.312
2011 Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Science Translational Medicine. 3: 89ra58. PMID 21715679 DOI: 10.1126/Scitranslmed.3002346  0.386
2011 Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5970-6. PMID 21508222 DOI: 10.1523/Jneurosci.4441-10.2011  0.403
2011 Cao H, Wu J, Lam S, Duan R, Newnham C, Molday RS, Graziotto JJ, Pierce EA, Hu J. Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP. Plos One. 6: e15860. PMID 21283520 DOI: 10.1371/Journal.Pone.0015860  0.415
2011 Graziotto JJ, Farkas MH, Bujakowska K, Deramaudt BM, Zhang Q, Nandrot EF, Inglehearn CF, Bhattacharya SS, Pierce EA. Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration. Investigative Ophthalmology & Visual Science. 52: 190-8. PMID 20811066 DOI: 10.1167/Iovs.10-5194  0.427
2008 Graziotto JJ, Inglehearn CF, Pack MA, Pierce EA. Decreased levels of the RNA splicing factor Prpf3 in mice and zebrafish do not cause photoreceptor degeneration. Investigative Ophthalmology & Visual Science. 49: 3830-8. PMID 18552388 DOI: 10.1167/Iovs.07-1483  0.388
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