Robert S. Molday - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Biochemistry, Neuroscience Biology

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Xu T, Molday LL, Molday RS. Retinal-phospholipid Schiff-base conjugates and their interaction with ABCA4, the ABC transporter associated with Stargardt disease. The Journal of Biological Chemistry. 299: 104614. PMID 36931393 DOI: 10.1016/j.jbc.2023.104614  0.344
2021 Molday RS, Garces FA, Scortecci JF, Molday LL. Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration. Progress in Retinal and Eye Research. 101036. PMID 34954332 DOI: 10.1016/j.preteyeres.2021.101036  0.377
2021 Skiba NP, Cady MA, Molday L, Han JYS, Lewis TR, Spencer WJ, Thompson WJ, Hiles S, Philp NJ, Molday RS, Arshavsky VY. TMEM67, TMEM237 and embigin in the complex with lactate transporter MCT1 are unique components of the photoreceptor outer segment plasma membrane. Molecular & Cellular Proteomics : McP. 100088. PMID 33933680 DOI: 10.1016/j.mcpro.2021.100088  0.305
2020 Garces FA, Scortecci JF, Molday RS. Functional Characterization of ABCA4 Missense Variants Linked to Stargardt Macular Degeneration. International Journal of Molecular Sciences. 22. PMID 33375396 DOI: 10.3390/ijms22010185  0.309
2020 Curtis SB, Molday LL, Garces FA, Molday RS. Functional Analysis and Classification of Homozygous and Hypomorphic ABCA4 Variants Associated with Stargardt Macular Degeneration. Human Mutation. PMID 32845050 DOI: 10.1002/Humu.24100  0.387
2020 Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, ... ... Molday RS, et al. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nature Medicine. PMID 32094924 DOI: 10.1038/S41591-020-0757-Z  0.311
2019 Novales Flamarique I, Ahmed AS, Cheng CL, Molday RS, Devlin RH. Growth hormone regulates opsin expression in the retina of a salmonid fish. Journal of Neuroendocrinology. e12804. PMID 31630448 DOI: 10.1111/Jne.12804  0.319
2019 Guissart C, Harrison AN, Benkirane M, Oncel I, Arslan EA, Chassevent AK, Baraῆano K, Larrieu L, Iascone M, Tenconi R, Claustres M, Eroglu-Ertugrul N, Calvas P, Topaloglu H, Molday RS, et al. ATP8A2-related disorders as recessive cerebellar ataxia. Journal of Neurology. PMID 31612321 DOI: 10.1007/S00415-019-09579-4  0.322
2019 Dyka FM, Molday LL, Chiodo V, Molday RS, Hauswirth WW. Dual ABCA4-AAV vector treatment reduces pathogenic retinal A2E accumulation in a mouse model of autosomal recessive Stargardt Disease. Human Gene Therapy. PMID 31418294 DOI: 10.1089/Hum.2019.132  0.425
2019 Choi H, Andersen JP, Molday RS. Expression and Functional Characterization of Missense Mutations in ATP8A2 Linked to Severe Neurological Disorders. Human Mutation. PMID 31397519 DOI: 10.1002/Humu.23889  0.363
2019 Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Molday RS, Andersen JP. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. Proceedings of the National Academy of Sciences of the United States of America. PMID 31371510 DOI: 10.1073/Pnas.1910211116  0.332
2019 Liou AY, Molday LL, Wang J, Andersen JP, Molday RS. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. The Journal of Biological Chemistry. PMID 30850395 DOI: 10.1074/Jbc.Ra118.007270  0.408
2019 Mikkelsen SA, Mogensen LS, Vilsen B, Molday RS, Vestergaard AL, Andersen JP. Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. The Journal of Biological Chemistry. PMID 30760526 DOI: 10.1074/Jbc.Ra118.007240  0.341
2019 Molday LL, Cheng CL, Molday RS. Cell-Specific Markers for the Identification of Retinal Cells and Subcellular Organelles by Immunofluorescence Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1834: 293-310. PMID 30324451 DOI: 10.1007/978-1-4939-8669-9_19  0.4
2018 Wang J, Molday LL, Hii T, Coleman JA, Wen T, Andersen JP, Molday RS. Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Scientific Reports. 8: 10795. PMID 30018401 DOI: 10.1038/S41598-018-29108-Z  0.318
2018 Garces F, Jiang K, Molday LL, Stöhr H, Weber BH, Lyons CJ, Maberley D, Molday RS. Correlating the Expression and Functional Activity of ABCA4 Disease Variants With the Phenotype of Patients With Stargardt Disease. Investigative Ophthalmology & Visual Science. 59: 2305-2315. PMID 29847635 DOI: 10.1167/Iovs.17-23364  0.349
2017 Molday LL, Wahl D, Sarunic M, Molday RS. Localization and Functional Characterization of the p.Asn965Ser (N965S) ABCA4 Variant in Mice Reveal Pathogenic Mechanisms Underlying Stargardt Macular Degeneration. Human Molecular Genetics. PMID 29145636 DOI: 10.1093/Hmg/Ddx400  0.459
2017 Gantzel RH, Mogensen LS, Mikkelsen SA, Vilsen B, Molday RS, Vestergaard AL, Andersen JP. Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates. Scientific Reports. 7: 10418. PMID 28874751 DOI: 10.1038/S41598-017-10741-Z  0.358
2017 Molday RS, Goldberg AF. Peripherin diverts ciliary ectosome release to photoreceptor disc morphogenesis. The Journal of Cell Biology. PMID 28400442 DOI: 10.1083/Jcb.201703020  0.378
2016 Chalat M, Moleschi K, Molday RS. C-terminus of the P4-ATPase ATP8A2 Functions in Protein Folding and Regulation of Phospholipid Flippase Activity. Molecular Biology of the Cell. PMID 27932490 DOI: 10.1091/Mbc.E16-06-0453  0.384
2016 Hickmott JW, Chen CY, Arenillas DJ, Korecki AJ, Lam SL, Molday LL, Bonaguro RJ, Zhou M, Chou AY, Mathelier A, Boye SL, Hauswirth WW, Molday RS, Wasserman WW, Simpson EM. PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina. Molecular Therapy. Methods & Clinical Development. 3: 16051. PMID 27556059 DOI: 10.1038/Mtm.2016.51  0.371
2016 Andersen JP, Vestergaard AL, Mikkelsen SA, Mogensen LS, Chalat M, Molday RS. P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas. Frontiers in Physiology. 7: 275. PMID 27458383 DOI: 10.3389/Fphys.2016.00275  0.362
2016 Bush M, Setiaputra D, Yip CK, Molday RS. Cog-Wheel Octameric Structure of RS1, the Discoidin Domain Containing Retinal Protein Associated with X-Linked Retinoschisis. Plos One. 11: e0147653. PMID 26812435 DOI: 10.1371/Journal.Pone.0147653  0.4
2015 Vestergaard AL, Mikkelsen SA, Coleman JA, Molday RS, Vilsen B, Andersen JP. Specific Mutations in Mammalian P4-ATPase ATP8A2 Catalytic Subunit Entail Differential Glycosylation of the Accessory CDC50A Subunit. Febs Letters. PMID 26592152 DOI: 10.1016/J.Febslet.2015.11.031  0.387
2015 Molday RS, Moritz OL. Photoreceptors at a glance. Journal of Cell Science. 128: 4039-45. PMID 26574505 DOI: 10.1242/Jcs.175687  0.472
2015 Molday RS. Insights into the Molecular Properties of ABCA4 and Its Role in the Visual Cycle and Stargardt Disease. Progress in Molecular Biology and Translational Science. 134: 415-31. PMID 26310168 DOI: 10.1016/Bs.Pmbts.2015.06.008  0.474
2015 Vinberg F, Wang T, Molday RS, Chen J, Kefalov VJ. A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease. Human Molecular Genetics. PMID 26246500 DOI: 10.1093/Hmg/Ddv319  0.392
2015 Thompson DA, Ali RR, Banin E, Branham KE, Flannery JG, Gamm DM, Hauswirth WW, Heckenlively JR, Iannaccone A, Jayasundera KT, Khan NW, Molday RS, Pennesi ME, Reh TA, Weleber RG, et al. Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. Investigative Ophthalmology & Visual Science. 56: 918-31. PMID 25667399 DOI: 10.1167/Iovs.14-16049  0.358
2015 Lee S, Uchida Y, Wang J, Matsudaira T, Nakagawa T, Kishimoto T, Mukai K, Inaba T, Kobayashi T, Molday RS, Taguchi T, Arai H. Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. The Embo Journal. 34: 669-88. PMID 25595798 DOI: 10.15252/Embj.201489703  0.418
2015 Zulliger R, Naash MI, Rajala RV, Molday RS, Azadi S. Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1. The Journal of Biological Chemistry. 290: 3488-99. PMID 25477517 DOI: 10.1074/Jbc.M114.616656  0.46
2015 Hickmott JW, Chen C, Arenillas DJ, Li Y, Molday LL, Korecki AJ, Ling Lam S, Ling Lam S, Bonaguro RJ, Zhou M, Chan AY, Boye SL, Hauswirth WW, Molday RS, Wasserman WW, et al. 599. Deep Informatics Utilized to Design MiniPromoters for Driving PAX6-Like Retinal Expression with AAV Molecular Therapy. 23: S238. DOI: 10.1016/S1525-0016(16)34208-3  0.367
2014 Molday LL, Molday RS. 1D4: a versatile epitope tag for the purification and characterization of expressed membrane and soluble proteins. Methods in Molecular Biology (Clifton, N.J.). 1177: 1-15. PMID 24943310 DOI: 10.1007/978-1-4939-1034-2_1  0.35
2014 Molday LL, Jefferies T, Molday RS. Insights into the role of RD3 in guanylate cyclase trafficking, photoreceptor degeneration, and Leber congenital amaurosis. Frontiers in Molecular Neuroscience. 7: 44. PMID 24904271 DOI: 10.3389/Fnmol.2014.00044  0.474
2014 Quazi F, Molday RS. ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal. Proceedings of the National Academy of Sciences of the United States of America. 111: 5024-9. PMID 24707049 DOI: 10.1073/Pnas.1400780111  0.436
2014 Vestergaard AL, Coleman JA, Lemmin T, Mikkelsen SA, Molday LL, Vilsen B, Molday RS, Dal Peraro M, Andersen JP. Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. Proceedings of the National Academy of Sciences of the United States of America. 111: E1334-43. PMID 24706822 DOI: 10.1073/Pnas.1321165111  0.377
2014 Coleman JA, Zhu X, Djajadi HR, Molday LL, Smith RS, Libby RT, John SW, Molday RS. Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival. Journal of Cell Science. 127: 1138-49. PMID 24413176 DOI: 10.1242/Jcs.145052  0.423
2013 Cheng CL, Molday RS. Interaction of 4.1G and cGMP-gated channels in rod photoreceptor outer segments. Journal of Cell Science. 126: 5725-34. PMID 24144699 DOI: 10.1242/Jcs.137679  0.374
2013 Quazi F, Molday RS. Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants. The Journal of Biological Chemistry. 288: 34414-26. PMID 24097981 DOI: 10.1074/Jbc.M113.508812  0.372
2013 Li L, Khan N, Hurd T, Ghosh AK, Cheng C, Molday R, Heckenlively JR, Swaroop A, Khanna H. Ablation of the X-linked retinitis pigmentosa 2 (Rp2) gene in mice results in opsin mislocalization and photoreceptor degeneration. Investigative Ophthalmology & Visual Science. 54: 4503-11. PMID 23745007 DOI: 10.1167/Iovs.13-12140  0.421
2013 Molday LL, Djajadi H, Yan P, Szczygiel L, Boye SL, Chiodo VA, Gregory-Evans K, Sarunic MV, Hauswirth WW, Molday RS. RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12. Human Molecular Genetics. 22: 3894-905. PMID 23740938 DOI: 10.1093/Hmg/Ddt244  0.428
2013 Tsybovsky Y, Orban T, Molday RS, Taylor D, Palczewski K. Molecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporter. Structure (London, England : 1993). 21: 854-60. PMID 23562398 DOI: 10.1016/J.Str.2013.03.001  0.415
2013 Reboul E, Dyka FM, Quazi F, Molday RS. Cholesterol transport via ABCA1: new insights from solid-phase binding assay. Biochimie. 95: 957-61. PMID 23201557 DOI: 10.1016/J.Biochi.2012.11.009  0.326
2013 Cheng CL, Djajadi H, Molday RS. Cell-specific markers for the identification of retinal cells by immunofluorescence microscopy. Methods in Molecular Biology (Clifton, N.J.). 935: 185-99. PMID 23150368 DOI: 10.1007/978-1-62703-080-9_12  0.394
2013 Coleman JA, Quazi F, Molday RS. Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport. Biochimica Et Biophysica Acta. 1831: 555-74. PMID 23103747 DOI: 10.1016/J.Bbalip.2012.10.006  0.391
2012 Quazi F, Lenevich S, Molday RS. ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer. Nature Communications. 3: 925. PMID 22735453 DOI: 10.1038/Ncomms1927  0.389
2012 Coleman JA, Vestergaard AL, Molday RS, Vilsen B, Andersen JP. Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2. Proceedings of the National Academy of Sciences of the United States of America. 109: 1449-54. PMID 22307598 DOI: 10.1073/Pnas.1108862109  0.378
2012 Molday RS, Kellner U, Weber BH. X-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanisms. Progress in Retinal and Eye Research. 31: 195-212. PMID 22245536 DOI: 10.1016/J.Preteyeres.2011.12.002  0.474
2012 Harkewicz R, Du H, Tong Z, Alkuraya H, Bedell M, Sun W, Wang X, Hsu YH, Esteve-Rudd J, Hughes G, Su Z, Zhang M, Lopes VS, Molday RS, Williams DS, et al. Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. The Journal of Biological Chemistry. 287: 11469-80. PMID 22199362 DOI: 10.1074/Jbc.M111.256073  0.408
2011 Cao H, Molday RS, Hu J. Gene therapy: light is finally in the tunnel. Protein & Cell. 2: 973-89. PMID 22231356 DOI: 10.1007/S13238-011-1126-Y  0.312
2011 Quazi F, Molday RS. Lipid transport by mammalian ABC proteins. Essays in Biochemistry. 50: 265-90. PMID 21967062 DOI: 10.1042/Bse0500265  0.405
2011 Peshenko IV, Olshevskaya EV, Azadi S, Molday LL, Molday RS, Dizhoor AM. Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins. Biochemistry. 50: 9511-9. PMID 21928830 DOI: 10.1021/Bi201342B  0.469
2011 Tsybovsky Y, Wang B, Quazi F, Molday RS, Palczewski K. Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4. Biochemistry. 50: 6855-66. PMID 21721517 DOI: 10.1021/Bi200774W  0.442
2011 Coleman JA, Molday RS. Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2. The Journal of Biological Chemistry. 286: 17205-16. PMID 21454556 DOI: 10.1074/Jbc.M111.229419  0.431
2011 Cao H, Wu J, Lam S, Duan R, Newnham C, Molday RS, Graziotto JJ, Pierce EA, Hu J. Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP. Plos One. 6: e15860. PMID 21283520 DOI: 10.1371/Journal.Pone.0015860  0.415
2011 Issaei A, Szczygiel L, Hossein-Javaheri N, Young M, Molday LL, Molday RS, Sarunic MV. Integrated scanning laser ophthalmoscopy and optical coherence tomography for quantitative multimodal imaging of retinal degeneration and autofluorescence Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7892. DOI: 10.1117/12.873982  0.336
2010 Jensen VL, Bialas NJ, Bishop-Hurley SL, Molday LL, Kida K, Nguyen PA, Blacque OE, Molday RS, Leroux MR, Riddle DL. Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. Plos Genetics. 6: e1001199. PMID 21124868 DOI: 10.1371/Journal.Pgen.1001199  0.388
2010 Azadi S, Molday LL, Molday RS. RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 21158-63. PMID 21078983 DOI: 10.1073/Pnas.1010460107  0.481
2010 van der Velden LM, Wichers CG, van Breevoort AE, Coleman JA, Molday RS, Berger R, Klomp LW, van de Graaf SF. Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases. The Journal of Biological Chemistry. 285: 40088-96. PMID 20947505 DOI: 10.1074/Jbc.M110.139006  0.382
2010 Tsybovsky Y, Molday RS, Palczewski K. The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease. Advances in Experimental Medicine and Biology. 703: 105-25. PMID 20711710 DOI: 10.1007/978-1-4419-5635-4_8  0.471
2010 Holopainen JM, Cheng CL, Molday LL, Johal G, Coleman J, Dyka F, Hii T, Ahn J, Molday RS. Interaction and localization of the retinitis pigmentosa protein RP2 and NSF in retinal photoreceptor cells. Biochemistry. 49: 7439-47. PMID 20669900 DOI: 10.1021/Bi1005249  0.496
2010 Molday RS, Zhang K. Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration. Progress in Lipid Research. 49: 476-92. PMID 20633576 DOI: 10.1016/J.Plipres.2010.07.002  0.466
2010 Zhong M, Molday RS. Binding of retinoids to ABCA4, the photoreceptor ABC transporter associated with Stargardt macular degeneration. Methods in Molecular Biology (Clifton, N.J.). 652: 163-76. PMID 20552428 DOI: 10.1007/978-1-60327-325-1_9  0.436
2009 Coleman JA, Kwok MC, Molday RS. Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes. The Journal of Biological Chemistry. 284: 32670-9. PMID 19778899 DOI: 10.1074/Jbc.M109.047415  0.435
2009 Zhang Y, Molday LL, Molday RS, Sarfare SS, Woodruff ML, Fain GL, Kraft TW, Pittler SJ. Knockout of GARPs and the β-subunit of the rod cGMP-gated channel disrupts disk morphogenesis and rod outer segment structural integrity. Journal of Cell Science. 122: 1192-200. PMID 19339551 DOI: 10.1242/Jcs.042531  0.373
2009 Wong JP, Reboul E, Molday RS, Kast J. A carboxy-terminal affinity tag for the purification and mass spectrometric characterization of integral membrane proteins. Journal of Proteome Research. 8: 2388-96. PMID 19236039 DOI: 10.1021/Pr801008C  0.386
2009 Molday RS, Zhong M, Quazi F. The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration. Biochimica Et Biophysica Acta. 1791: 573-83. PMID 19230850 DOI: 10.1016/J.Bbalip.2009.02.004  0.497
2009 Zhong M, Molday LL, Molday RS. Role of the C terminus of the photoreceptor ABCA4 transporter in protein folding, function, and retinal degenerative diseases. The Journal of Biological Chemistry. 284: 3640-9. PMID 19056738 DOI: 10.1074/Jbc.M806580200  0.512
2009 Walia S, Fishman GA, Molday RS, Dyka FM, Kumar NM, Ehlinger MA, Stone EM. Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisin. American Journal of Ophthalmology. 147: 111-115.e1. PMID 18834580 DOI: 10.1016/J.Ajo.2008.07.041  0.308
2009 Molday RS, Zhong M. Photoreceptor ABC Transporter ABCA4: Its Role in the Visual Cycle and Retinal Degenerative Diseases Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2723  0.531
2008 Dyka FM, Wu WW, Pfeifer TA, Molday LL, Grigliatti TA, Molday RS. Characterization and purification of the discoidin domain-containing protein retinoschisin and its interaction with galactose. Biochemistry. 47: 9098-106. PMID 18690710 DOI: 10.1021/Bi800938G  0.405
2008 Togashi K, von Schimmelmann MJ, Nishiyama M, Lim CS, Yoshida N, Yun B, Molday RS, Goshima Y, Hong K. Cyclic GMP-gated CNG channels function in Sema3A-induced growth cone repulsion. Neuron. 58: 694-707. PMID 18549782 DOI: 10.1016/J.Neuron.2008.03.017  0.303
2008 Janssen A, Min SH, Molday LL, Tanimoto N, Seeliger MW, Hauswirth WW, Molday RS, Weber BHF. Effect of Late-stage therapy on disease progression in AAV-mediated rescue of photoreceptor cells in the retinoschisin-deficient mouse Molecular Therapy. 16: 1010-1017. PMID 18388913 DOI: 10.1038/Mt.2008.57  0.331
2008 Kwok MC, Holopainen JM, Molday LL, Foster LJ, Molday RS. Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusion. Molecular & Cellular Proteomics : McP. 7: 1053-66. PMID 18245078 DOI: 10.1074/Mcp.M700571-Mcp200  0.446
2007 Hornan DM, Peirson SN, Hardcastle AJ, Molday RS, Cheetham ME, Webster AR. Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling. Investigative Ophthalmology & Visual Science. 48: 5388-96. PMID 18055785 DOI: 10.1167/Iovs.07-0355  0.401
2007 Molday RS. ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration. Journal of Bioenergetics and Biomembranes. 39: 507-17. PMID 17994272 DOI: 10.1007/S10863-007-9118-6  0.507
2007 Molday LL, Wu WW, Molday RS. Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex. The Journal of Biological Chemistry. 282: 32792-801. PMID 17804407 DOI: 10.1074/Jbc.M706321200  0.463
2007 Dyka FM, Molday RS. Coexpression and interaction of wild-type and missense RS1 mutants associated with X-linked retinoschisis: its relevance to gene therapy. Investigative Ophthalmology & Visual Science. 48: 2491-7. PMID 17525175 DOI: 10.1167/Iovs.06-1465  0.412
2007 Mordes D, Yuan L, Xu L, Kawada M, Molday RS, Wu JY. Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa Neurobiology of Disease. 26: 291-300. PMID 17350276 DOI: 10.1016/J.Nbd.2006.08.026  0.365
2006 Molday RS, Beharry S, Ahn J, Zhong M. Binding of N-retinylidene-PE to ABCA4 and a model for its transport across membranes. Advances in Experimental Medicine and Biology. 572: 465-70. PMID 17249610 DOI: 10.1007/0-387-32442-9_64  0.32
2006 Molday LL, Min SH, Seeliger MW, Wu WW, Dinculescu A, Timmers AM, Janssen A, Tonagel F, Hudl K, Weber BH, Hauswirth WW, Molday RS. Disease mechanisms and gene therapy in a mouse model for X-linked retinoschisis. Advances in Experimental Medicine and Biology. 572: 283-9. PMID 17249585 DOI: 10.1007/0-387-32442-9_39  0.349
2006 Iannaccone A, Mura M, Dyka FM, Ciccarelli ML, Yashar BM, Ayyagari R, Jablonski MM, Molday RS. An unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutation. Vision Research. 46: 3845-52. PMID 16884758 DOI: 10.1016/J.Visres.2006.06.011  0.393
2005 Grayson C, Molday RS. Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4. The Journal of Biological Chemistry. 280: 32521-30. PMID 16036915 DOI: 10.1074/Jbc.M503411200  0.406
2005 Min SH, Molday LL, Seeliger MW, Dinculescu A, Timmers AM, Janssen A, Tonagel F, Tanimoto N, Weber BH, Molday RS, Hauswirth WW. Prolonged recovery of retinal structure/function after gene therapy in an Rs1h-deficient mouse model of x-linked juvenile retinoschisis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 644-51. PMID 16027044 DOI: 10.1016/J.Ymthe.2005.06.002  0.39
2005 Bennis M, Molday RS, Versaux-Botteri C, Repérant J, Jeanny JC, McDevitt DS. Rhodopsin-like immunoreactivity in the 'all cone' retina of the chameleon (Chameleo chameleo). Experimental Eye Research. 80: 623-7. PMID 15862168 DOI: 10.1016/J.Exer.2004.11.004  0.391
2005 Lin PJ, Williams WP, Luu Y, Molday RS, Orlowski J, Numata M. Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7. Journal of Cell Science. 118: 1885-97. PMID 15840657 DOI: 10.1242/Jcs.02315  0.422
2005 Wu WW, Wong JP, Kast J, Molday RS. RS1, a discoidin domain-containing retinal cell adhesion protein associated with X-linked retinoschisis, exists as a novel disulfide-linked octamer. The Journal of Biological Chemistry. 280: 10721-30. PMID 15644328 DOI: 10.1074/Jbc.M413117200  0.427
2005 Stöhr H, Molday LL, Molday RS, Weber BH, Biedermann B, Reichenbach A, Krämer F. Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina. The Journal of Comparative Neurology. 481: 31-41. PMID 15558731 DOI: 10.1002/Cne.20367  0.485
2004 Beharry S, Zhong M, Molday RS. N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR). The Journal of Biological Chemistry. 279: 53972-9. PMID 15471866 DOI: 10.1074/Jbc.M405216200  0.44
2004 Molday RS, Molday LL, Loewen CJ. Role of subunit assembly in autosomal dominant retinitis pigmentosa linked to mutations in peripherin 2. Novartis Foundation Symposium. 255: 95-112; discussion 1. PMID 14750599 DOI: 10.1002/0470092645.Ch8  0.765
2003 Loewen CJ, Moritz OL, Tam BM, Papermaster DS, Molday RS. The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa. Molecular Biology of the Cell. 14: 3400-13. PMID 12925772 DOI: 10.1091/Mbc.E03-02-0077  0.76
2003 Ahn J, Beharry S, Molday LL, Molday RS. Functional interaction between the two halves of the photoreceptor-specific ATP binding cassette protein ABCR (ABCA4). Evidence for a non-exchangeable ADP in the first nucleotide binding domain. The Journal of Biological Chemistry. 278: 39600-8. PMID 12888572 DOI: 10.1074/Jbc.M304236200  0.478
2003 Wu WW, Molday RS. Defective discoidin domain structure, subunit assembly, and endoplasmic reticulum processing of retinoschisin are primary mechanisms responsible for X-linked retinoschisis. The Journal of Biological Chemistry. 278: 28139-46. PMID 12746437 DOI: 10.1074/Jbc.M302464200  0.446
2002 Warren R, Molday RS. Regulation of the rod photoreceptor cyclic nucleotide-gated channel. Advances in Experimental Medicine and Biology. 514: 205-23. PMID 12596923 DOI: 10.1007/978-1-4615-0121-3_12  0.337
2002 Zhong H, Molday LL, Molday RS, Yau KW. The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry. Nature. 420: 193-8. PMID 12432397 DOI: 10.1038/Nature01201  0.33
2002 Weber BH, Schrewe H, Molday LL, Gehrig A, White KL, Seeliger MW, Jaissle GB, Friedburg C, Tamm E, Molday RS. Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure. Proceedings of the National Academy of Sciences of the United States of America. 99: 6222-7. PMID 11983912 DOI: 10.1073/Pnas.092528599  0.403
2001 Poetsch A, Molday LL, Molday RS. The cGMP-gated Channel and Related Glutamic Acid-rich Proteins Interact with Peripherin-2 at the Rim Region of Rod Photoreceptor Disc Membranes Journal of Biological Chemistry. 276: 48009-48016. PMID 11641407 DOI: 10.1074/Jbc.M108941200  0.44
2001 Bungert S, Molday LL, Molday RS. Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: Identification of N-linked glycosylation sites Journal of Biological Chemistry. 276: 23539-23546. PMID 11320094 DOI: 10.1074/Jbc.M101902200  0.405
2001 Loewen CJ, Moritz OL, Molday RS. Molecular characterization of peripherin-2 and rom-1 mutants responsible for digenic retinitis pigmentosa. The Journal of Biological Chemistry. 276: 22388-96. PMID 11297544 DOI: 10.1074/Jbc.M011710200  0.732
2001 Molday LL, Hicks D, Sauer CG, Weber BHF, Molday RS. Expression of X-linked retinoschisis protein RS1 in photoreceptor and bipolar cells Investigative Ophthalmology and Visual Science. 42: 816-825. PMID 11222545  0.318
2000 Molday LL, Rabin AR, Molday RS. ABCR expression in foveal cone photoreceptors and its role in Stargardt macular dystrophy Nature Genetics. 25: 257-258. PMID 10888868 DOI: 10.1016/S0002-9394(00)00756-X  0.383
2000 Clarke G, Goldberg AF, Vidgen D, Collins L, Ploder L, Schwarz L, Molday LL, Rossant J, Szél A, Molday RS, Birch DG, McInnes RR. Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis. Nature Genetics. 25: 67-73. PMID 10802659 DOI: 10.1038/75621  0.456
2000 Goldberg AFX, Molday RS. Expression and characterization of peripherin/rds-rom-1 complexes and mutants implicated in retinal degenerative diseases Methods in Enzymology. 316: 671-687. PMID 10800708 DOI: 10.1016/S0076-6879(00)16756-4  0.464
2000 Ahn J, Wong JT, Molday RS. The effect of lipid environment and retinoids on the ATPase activity of ABCR, the photoreceptor ABC transporter responsible for Stargardt macular dystrophy. The Journal of Biological Chemistry. 275: 20399-405. PMID 10767284 DOI: 10.1074/Jbc.M000555200  0.423
2000 Ahn J, Molday RS. Purification and characterization of ABCR from bovine rod outer segments Methods in Enzymology. 315: 864-879. PMID 10736746 DOI: 10.1016/S0076-6879(00)15887-2  0.375
2000 Loewen CJ, Molday RS. Disulfide-mediated oligomerization of Peripherin/Rds and Rom-1 in photoreceptor disk membranes. Implications for photoreceptor outer segment morphogenesis and degeneration. The Journal of Biological Chemistry. 275: 5370-8. PMID 10681511 DOI: 10.1074/Jbc.275.8.5370  0.748
1999 Molday RS, Warren R, Loewen C, Molday L. Cyclic GMP-gated channel and peripherin/rds-rom-1 complex of rod cells. Novartis Foundation Symposium. 224: 249-61; discussion 2. PMID 10614055 DOI: 10.1002/9780470515693.Ch14  0.722
1999 Sun H, Molday RS, Nathans J. Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease. The Journal of Biological Chemistry. 274: 8269-81. PMID 10075733 DOI: 10.1074/jbc.274.12.8269  0.344
1998 Molday RS, Molday LL. Purification, characterization, and reconstitution of cyclic nucleotide- gated channels Methods in Enzymology. 294: 246-260. PMID 9916231 DOI: 10.1016/S0076-6879(99)94015-6  0.325
1998 Molday RS. Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases: The Friedenwald Lecture Investigative Ophthalmology and Visual Science. 39: 2493-2513. PMID 9856758  0.391
1998 Molday RS, Molday LL. Molecular properties of the cGMP-gated channel of rod photoreceptors Vision Research. 38: 1315-1323. PMID 9666999 DOI: 10.1016/S0042-6989(97)00409-4  0.413
1998 Kim TSY, Reid DM, Molday RS. Structure-function relationships and localization of the Na/Ca-K exchanger in rod photoreceptors Journal of Biological Chemistry. 273: 16561-16567. PMID 9632727 DOI: 10.1074/Jbc.273.26.16561  0.446
1998 Nasonkin I, Illing M, Koehler MR, Schmid M, Molday RS, Weber BHF. Mapping of the rod photoreceptor ABC transporter (ABCR) to 1p21-p22.1 and identification of novel mutations in Stargardt's disease Human Genetics. 102: 21-26. PMID 9490294 DOI: 10.1007/S004390050649  0.355
1998 Goldberg AF, Loewen CJ, Molday RS. Cysteine residues of photoreceptor peripherin/rds: role in subunit assembly and autosomal dominant retinitis pigmentosa. Biochemistry. 37: 680-5. PMID 9425091 DOI: 10.1021/Bi972036I  0.749
1997 Schwarzer A, Kim TS, Hagen V, Molday RS, Bauer PJ. The Na/Ca-K exchanger of rod photoreceptor exists as dimer in the plasma membrane. Biochemistry. 36: 13667-76. PMID 9354636 DOI: 10.1021/Bi9710232  0.354
1997 Fariss RN, Molday RS, Fisher SK, Matsumoto B. Evidence from normal and degenerating photoreceptors that two outer segment integral membrane proteins have separate transport pathways. The Journal of Comparative Neurology. 387: 148-56. PMID 9331178 DOI: 10.1002/(Sici)1096-9861(19971013)387:1<148::Aid-Cne12>3.0.Co;2-Q  0.482
1997 Illing M, Molday LL, Molday RS. The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily Journal of Biological Chemistry. 272: 10303-10310. PMID 9092582 DOI: 10.1074/Jbc.272.15.10303  0.46
1996 Colville CA, Molday RS. Primary structure and expression of the human β-subunit and related proteins of the rod photoreceptor cGMP-gated channel Journal of Biological Chemistry. 271: 32968-32974. PMID 8955140 DOI: 10.1074/Jbc.271.51.32968  0.363
1996 Goldberg AFX, Molday RS. Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1 Proceedings of the National Academy of Sciences of the United States of America. 93: 13726-13730. PMID 8943002 DOI: 10.1073/Pnas.93.24.13726  0.48
1996 Molday RS. Calmodulin regulation of cyclic-nucleotide-gated channels Current Opinion in Neurobiology. 6: 445-452. PMID 8794100 DOI: 10.1016/S0959-4388(96)80048-1  0.31
1996 Goldberg AFX, Molday RS. Subunit composition of the peripherin/rds-rom-1 disk rim complex from rod photoreceptors: Hydrodynamic evidence for a tetrameric quaternary structure Biochemistry. 35: 6144-6149. PMID 8634257 DOI: 10.1021/Bi960259N  0.455
1996 Moritz OL, Molday RS. Molecular cloning, membrane topology, and localization of bovine rom-1 in rod and cone photoreceptor cells Investigative Ophthalmology and Visual Science. 37: 352-362. PMID 8603840  0.378
1996 Moritz OL, Molday RS. Generation and characterization of C-terminal deletion mutants of bovine rom-1 and peripherin/rds Investigative Ophthalmology and Visual Science. 37.  0.325
1996 Goldberg AFX, Molday RS. Rom-1 - Dependent subunit assembly of a peripherin/rds mutant linked to a digenically inherited form of retinitis pigmentosa Investigative Ophthalmology and Visual Science. 37.  0.34
1995 Goldberg AFX, Moritz OL, Molday RS. Heterologous expression of photoreceptor peripherin/rds and rom-1 in COS-1 cells: Assembly, interactions, and localization of multisubunit complexes Biochemistry. 34: 14213-14219. PMID 7578020 DOI: 10.1021/Bi00043A028  0.499
1994 Chen TY, Illing M, Molday LL, Hsu YT, Yau KW, Molday RS. Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation. Proceedings of the National Academy of Sciences of the United States of America. 91: 11757-61. PMID 7526403 DOI: 10.1073/Pnas.91.24.11757  0.376
1994 Molday RS. Peripherin/rds and rom-1: Molecular properties and role in photoreceptor cell degeneration Progress in Retinal and Eye Research. 13: 271-299. DOI: 10.1016/1350-9462(94)90013-2  0.352
1993 Hsu YT, Wong SY, Connell GJ, Molday RS. Structural and functional properties of rhodopsin from rod outer segment disk and plasma membrane. Biochimica Et Biophysica Acta. 1145: 85-92. PMID 8422414 DOI: 10.1016/0005-2736(93)90384-C  0.382
1993 Bönigk W, Altenhofen W, Müller F, Dose A, Illing M, Molday RS, Kaupp UB. Rod and cone photoreceptor cells express distinct genes for cGMP-gated channels Neuron. 10: 865-877. PMID 7684234 DOI: 10.1016/0896-6273(93)90202-3  0.41
1993 Hsu YT, Molday RS. Modulation of the cGMP-gated channel of rod photoreceptor cells by calmodulin. Nature. 361: 76-9. PMID 7678445 DOI: 10.1038/361076A0  0.386
1993 Molday RS, Molday LL. Isolation and Characterization of Rod Outer Segment Disk and Plasma Membranes Methods in Neurosciences. 15: 131-150. DOI: 10.1016/B978-0-12-185279-5.50014-5  0.407
1992 Arikawa K, Molday LL, Molday RS, Williams DS. Localization of peripherin/rds in the disk membranes of cone and rod photoreceptors: Relationship to disk membrane morphogenesis and retinal degeneration Journal of Cell Biology. 116: 659-667. PMID 1730772 DOI: 10.1083/Jcb.116.3.659  0.489
1992 Reid DM, Laird DW, Molday RS. Characterization and application of an in vitro detection system for studying the binding and phagocytosis of rod outer segments by retinal pigment epithelial cells Experimental Eye Research. 54: 775-783. PMID 1623963 DOI: 10.1016/0014-4835(92)90033-O  0.331
1992 Bascom RA, Manara S, Collins L, Molday RS, Kalnins VI, Mclnnes RR. Cloning of the CDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies Neuron. 8: 1171-1184. PMID 1610568 DOI: 10.1016/0896-6273(92)90137-3  0.504
1992 Olsson JE, Gordon JW, Pawlyk BS, Roof D, Hayes A, Molday RS, Mukai S, Cowley GS, Berson EL, Dryja TP. Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa Neuron. 9: 815-830. PMID 1418997 DOI: 10.1016/0896-6273(92)90236-7  0.413
1992 Wässle H, Grünert U, Cook NJ, Molday RS. The cGMP-gated channel of rod outer segments is not localized in bipolar cells of the mammalian retina. Neuroscience Letters. 134: 199-202. PMID 1375352 DOI: 10.1016/0304-3940(92)90516-A  0.384
1991 Connell G, Bascom R, Molday L, Reid D, McInnes RR, Molday RS. Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse Proceedings of the National Academy of Sciences of the United States of America. 88: 723-726. PMID 1992463 DOI: 10.1073/Pnas.88.3.723  0.498
1991 Molday RS, Molday LL, Dosé A, Clark-Lewis I, Illing M, Cook NJ, Eismann E, Benjamin Kaupp U. The cGMP-gated channel of the rod photoreceptor cell characterization and orientation of the amino terminus Journal of Biological Chemistry. 266: 21917-21922. PMID 1718987  0.306
1990 Hsu SC, Molday RS. Glyceraldehyde-3-phosphate dehydrogenase is a major protein associated with the plasma membrane of retinal photoreceptor outer segments Journal of Biological Chemistry. 265: 13308-13313. PMID 2376595  0.324
1990 Molday RS. Molecular cloning, primary structure, and orientation of the vertebrate photoreceptor cell protein peripherin in the rod outer segment disk membrane Biochemistry ®. 29: 4691-4698. PMID 2372552 DOI: 10.1021/Bi00471A025  0.383
1990 Doi T, Molday RS, Gobind Khorana H. Role of the intradiscal domain in rhodopsin assembly and function Proceedings of the National Academy of Sciences of the United States of America. 87: 4991-4995. PMID 2367520 DOI: 10.1073/Pnas.87.13.4991  0.359
1990 Reid DM, Friedel U, Molday RS, Cook NJ. Identification of the sodium-calcium exchanger as the major ricin-binding glycoprotein of bovine rod outer segments and its localization to the plasma membrane Biochemistry. 29: 1601-1607. PMID 2334719 DOI: 10.1021/Bi00458A035  0.39
1988 Molday RS. Monoclonal antibodies to rhodopsin and other proteins of rod outer segments Progress in Retinal Research. 8: 173-209. DOI: 10.1016/0278-4327(88)90025-9  0.349
1987 Oprian DD, Molday RS, Kaufman RJ, Khorana HG. Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 8874-8. PMID 2962193 DOI: 10.1073/Pnas.84.24.8874  0.316
1987 Molday RS, Molday LL. Differences in the protein composition of bovine retinal rod outer segment disk and plasma membranes isolated by a ricin-gold-dextran density perturbation method Journal of Cell Biology. 105: 2589-2601. PMID 2447095 DOI: 10.1083/Jcb.105.6.2589  0.401
1987 Molday LL, Molday RS. Glycoproteins specific for the retinal rod outer segment plasma membrane Bba - Biomembranes. 897: 335-340. PMID 2434131 DOI: 10.1016/0005-2736(87)90430-5  0.44
1987 Molday RS, Hicks D, Molday L. Peripherin. A rim-specific membrane protein of rod outer segment discs Investigative Ophthalmology and Visual Science. 28: 50-61. PMID 2433249  0.301
1986 Wong S, Molday RS. A spectrin-like protein in retinal rod outer segments Biochemistry. 25: 6294-6300. PMID 3790524 DOI: 10.1021/Bi00368A069  0.416
1986 Hicks D, Molday RS. Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin Experimental Eye Research. 42: 55-71. PMID 2420630 DOI: 10.1016/0014-4835(86)90017-5  0.336
1985 Molday RS, MacKenzie D. Inhibition of monoclonal antibody binding and proteolysis by light-induced phosphorylation of rhodopsin Biochemistry. 24: 776-781. PMID 2581604 DOI: 10.1021/Bi00324A036  0.341
1983 Loo TW, Stan-Lotter H, Mackenzie D, Molday RS, Bragg PD. Interaction of Escherichia coli F1-ATPase with dicyclohexylcarbodiimide-binding polypeptide Bba - Biomembranes. 733: 274-282. PMID 6224513 DOI: 10.1016/0005-2736(83)90532-1  0.347
1979 Clark SP, Molday RS. Orientation of membrane glycoproteins in sealed rod outer segment disks Biochemistry. 18: 5868-5873. PMID 518872 DOI: 10.1021/Bi00593A017  0.362
1979 Molday RS, Molday LL. Identification and characterization of multiple forms of rhodopsin and minor proteins in frog and bovine rod outer segment disc membranes. Electrophoresis, lectin labeling, and proteolysis studies Journal of Biological Chemistry. 254: 4653-4660. PMID 312291  0.312
1976 Molday R, Jaffe R, McMahon D. Concanavalin a and wheat germ agglutinin receptors on dictyostelium: Their visualization by scanning electron microscopy with microspheres Journal of Cell Biology. 71: 314-322. PMID 988030 DOI: 10.1083/Jcb.71.1.314  0.311
1973 Huang HV, Molday RS, Dreyer WJ. Isoelectric focusing of rod outer segment membrane proteins. Febs Letters. 37: 285-90. PMID 4128507 DOI: 10.1016/0014-5793(73)80479-X  0.308
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