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Warren J. Strittmatter, MD - Publications

Affiliations: 
Neurology Duke University, Durham, NC 
Area:
Alzheimer's disease
Website:
http://www.dukehealth.org/physicians/warren_j_strittmatter

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Popiel HA, Takeuchi T, Burke JR, Strittmatter WJ, Toda T, Wada K, Nagai Y. Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 440-6. PMID 23504628 DOI: 10.1007/s13311-013-0184-7  0.64
2013 Strittmatter WJ. Bathing the brain. The Journal of Clinical Investigation. 123: 1013-5. PMID 23434595 DOI: 10.1172/JCI68241  0.64
2012 Strittmatter WJ. Alzheimer’s disease: the new promise. The Journal of Clinical Investigation. 122: 1191. PMID 22754953 DOI: 10.1172/JCI62745  0.64
2012 Strittmatter WJ. Medicine. Old drug, new hope for Alzheimer's disease. Science (New York, N.Y.). 335: 1447-8. PMID 22442467 DOI: 10.1126/science.1220725  0.64
2011 Swaminathan M, Nicoara A, Phillips-Bute BG, Aeschlimann N, Milano CA, Mackensen GB, Podgoreanu MV, Velazquez EJ, Stafford-Smith M, Mathew JP. Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery. The Annals of Thoracic Surgery. 91: 1844-50. PMID 21492828 DOI: 10.1016/j.athoracsur.2011.02.008  0.64
2010 Heinzen EL, Need AC, Hayden KM, Chiba-Falek O, Roses AD, Strittmatter WJ, Burke JR, Hulette CM, Welsh-Bohmer KA, Goldstein DB. Genome-wide scan of copy number variation in late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 69-77. PMID 20061627 DOI: 10.3233/JAD-2010-1212  0.64
2009 Need AC, Ge D, Weale ME, Maia J, Feng S, Heinzen EL, Shianna KV, Yoon W, KasperaviciÅ«te D, Gennarelli M, Strittmatter WJ, Bonvicini C, Rossi G, Jayathilake K, Cola PA, et al. A genome-wide investigation of SNPs and CNVs in schizophrenia. Plos Genetics. 5: e1000373. PMID 19197363 DOI: 10.1371/journal.pgen.1000373  0.64
2008 Lai TS, Liu Y, Tucker T, Daniel KR, Sane DC, Toone E, Burke JR, Strittmatter WJ, Greenberg CS. Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries. Chemistry & Biology. 15: 969-78. PMID 18804034 DOI: 10.1016/j.chembiol.2008.07.015  0.64
2008 Weinberg JB, Volkheimer AD, Mihovilovic M, Jiang N, Chen Y, Bond K, Moore JO, Gockerman JP, Diehl LF, de Castro CM, Rizzieri DA, Levesque MC, Dekroon R, Strittmatter WJ. Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia. Leukemia. 22: 2184-92. PMID 18784741 DOI: 10.1038/leu.2008.241  0.64
2007 Hamuro L, Zhang G, Tucker TJ, Self C, Strittmatter WJ, Burke JR. Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay. Assay and Drug Development Technologies. 5: 629-36. PMID 17939755 DOI: 10.1089/adt.2007.083  0.64
2007 O'Grady G, Boyles AL, Speer M, DeRuyter F, Strittmatter W, Worley G. Apolipoprotein E alleles and sensorineural hearing loss International Journal of Audiology. 46: 183-186. PMID 17454231 DOI: 10.1080/14992020601145294  0.64
2007 Mihovilovic M, Robinette JB, DeKroon RM, Sullivan PM, Strittmatter WJ. High-fat/high-cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDL. Journal of Lipid Research. 48: 806-15. PMID 17264352 DOI: 10.1194/jlr.M600201-JLR200  0.64
2007 Osorio C, Sullivan PM, He DN, Mace BE, Ervin JF, Strittmatter WJ, Alzate O. Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. Neurobiology of Aging. 28: 1853-62. PMID 17050040 DOI: 10.1016/j.neurobiolaging.2006.08.011  0.64
2006 Kenan DJ, Strittmatter WJ, Burke JR. Phage display screening for peptides that inhibit polyglutamine aggregation. Methods in Enzymology. 413: 253-73. PMID 17046401 DOI: 10.1016/S0076-6879(06)13014-1  0.64
2006 DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ. APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2. Circulation Research. 99: 829-36. PMID 16973905 DOI: 10.1161/01.RES.0000245479.03190.9f  0.64
2006 Puranam KL, Wu G, Strittmatter WJ, Burke JR. Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. Biochemical and Biophysical Research Communications. 341: 607-13. PMID 16427603 DOI: 10.1016/j.bbrc.2006.01.007  0.64
2006 Halford J, Mazeika G, Slifer S, Speer M, Saunders AM, Strittmatter WJ, Morgenlander JC. APOE2 allele increased in tardive dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. 21: 540-2. PMID 16261623 DOI: 10.1002/mds.20768  0.64
2005 Blackman JA, Worley G, Strittmatter WJ. Apolipoprotein E and brain injury: implications for children. Developmental Medicine and Child Neurology. 47: 64-70. PMID 15686292 DOI: 10.1017/S0012162205000113  0.64
2004 Colton CA, Xu Q, Burke JR, Bae SY, Wakefield JK, Nair A, Strittmatter WJ, Vitek MP. Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7118-27. PMID 15306645 DOI: 10.1523/JNEUROSCI.1233-04.2004  0.64
2004 Popiel HA, Nagai Y, Onodera O, Inui T, Fujikake N, Urade Y, Strittmatter WJ, Burke JR, Ichikawa A, Toda T. Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity. Biochemical and Biophysical Research Communications. 317: 1200-6. PMID 15094397 DOI: 10.1016/j.bbrc.2004.03.161  0.64
2004 Lai TS, Tucker T, Burke JR, Strittmatter WJ, Greenberg CS. Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats. Journal of Neurochemistry. 88: 1253-60. PMID 15009681 DOI: 10.1046/j.1471-4159.2003.02249.x  0.64
2004 Colton CA, Needham LK, Brown C, Cook D, Rasheed K, Burke JR, Strittmatter WJ, Schmechel DE, Vitek MP. APOE genotype-specific differences in human and mouse macrophage nitric oxide production. Journal of Neuroimmunology. 147: 62-7. PMID 14741429 DOI: 10.1016/j.jneuroim.2003.10.015  0.64
2003 Mackensen GB, Ti LK, Phillips-Bute BG, Mathew JP, Newman MF, Grocott HP. Cerebral embolization during cardiac surgery: impact of aortic atheroma burden. British Journal of Anaesthesia. 91: 656-61. PMID 14570786 DOI: 10.1093/bja/aeg234  0.64
2003 Nagai Y, Fujikake N, Ohno K, Higashiyama H, Popiel HA, Rahadian J, Yamaguchi M, Strittmatter WJ, Burke JR, Toda T. Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila. Human Molecular Genetics. 12: 1253-9. PMID 12761040 DOI: 10.1093/hmg/ddg144  0.64
2003 DeKroon RM, Mihovilovic M, Goodger ZV, Robinette JB, Sullivan PM, Saunders AM, Strittmatter WJ. ApoE genotype-specific inhibition of apoptosis. Journal of Lipid Research. 44: 1566-73. PMID 12754278 DOI: 10.1194/jlr.M300097-JLR200  0.64
2003 Bedlack RS, Edelman D, Gibbs JW, Kelling D, Strittmatter W, Saunders AM, Morgenlander J. APOE genotype is a risk factor for neuropathy severity in diabetic patients. Neurology. 60: 1022-4. PMID 12654974  0.64
2003 Panov AV, Burke JR, Strittmatter WJ, Greenamyre JT. In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease. Archives of Biochemistry and Biophysics. 410: 1-6. PMID 12559971 DOI: 10.1016/S0003-9861(02)00585-4  0.64
2002 Panov AV, Gutekunst CA, Leavitt BR, Hayden MR, Burke JR, Strittmatter WJ, Greenamyre JT. Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nature Neuroscience. 5: 731-6. PMID 12089530 DOI: 10.1038/nn884  0.64
2002 Swaminathan M, McCreath BJ, Phillips-Bute BG, Newman MF, Mathew JP, Smith PK, Blumenthal JA, Stafford-Smith M, Grocott HP, Hill SE, Reves JG, Schwinn DA, Warner D, Harris M, Kirchner JL, ... ... Strittmatter WJ, et al. Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction Anesthesia and Analgesia. 95: 1-8. PMID 12088934  0.64
2002 Shimohata T, Sato A, Burke JR, Strittmatter WJ, Tsuji S, Onodera O. Expanded polyglutamine stretches form an 'aggresome'. Neuroscience Letters. 323: 215-8. PMID 11959423 DOI: 10.1016/S0304-3940(02)00162-3  0.64
2002 Strittmatter WJ, Bova Hill C. Molecular biology of apolipoprotein E. Current Opinion in Lipidology. 13: 119-23. PMID 11891413 DOI: 10.1097/00041433-200204000-00002  0.64
2002 Grigore AM, Grocott HP, Mathew JP, Phillips-Bute B, Stanley TO, Butler A, Landolfo KP, Reves JG, Blumenthal JA, Newman MF, Clements FM, De Bruijn N, Grichnik K, Hill SE, Hilton AK, ... ... Strittmatter WJ, et al. The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery Anesthesia and Analgesia. 94: 4-10. PMID 11772792  0.64
2001 Ren H, Nagai Y, Tucker T, Strittmatter WJ, Burke JR. Amino acid sequence requirements of peptides that inhibit polyglutamine-protein aggregation and cell death. Biochemical and Biophysical Research Communications. 288: 703-10. PMID 11676500 DOI: 10.1006/bbrc.2001.5783  0.64
2001 Strittmatter WJ. Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms. Biochemical Society Symposium. 101-9. PMID 11447826  0.64
2001 Dranovsky A, Vincent I, Gregori L, Schwarzman A, Colflesh D, Enghild J, Strittmatter W, Davies P, Goldgaber D. Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology. Neurobiology of Aging. 22: 517-28. PMID 11445251 DOI: 10.1016/S0197-4580(00)00248-7  0.64
2001 Fullerton SM, Shirman GA, Strittmatter WJ, Matthew WD. Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. Experimental Neurology. 169: 13-22. PMID 11312553 DOI: 10.1006/exnr.2001.7631  0.64
2000 Strittmatter WJ. Apolipoprotein E and Alzheimer's disease. Annals of the New York Academy of Sciences. 924: 91-2. PMID 11193808  0.64
2000 Bedlack RS, Strittmatter WJ, Morgenlander JC. Apolipoprotein E and neuromuscular disease: a critical review of the literature. Archives of Neurology. 57: 1561-5. PMID 11074787  0.64
2000 Chew ST, Newman MF, White WD, Conlon PJ, Saunders AM, Strittmatter WJ, Landolfo K, Grocott HP, Stafford-Smith M. Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients. Anesthesiology. 93: 325-31. PMID 10910477  0.64
2000 Saunders AM, Trowers MK, Shimkets RA, Blakemore S, Crowther DJ, Mansfield TA, Wallace DM, Strittmatter WJ, Roses AD. The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. Biochimica Et Biophysica Acta. 1502: 85-94. PMID 10899434 DOI: 10.1016/S0925-4439(00)00035-1  0.64
2000 Nagai Y, Tucker T, Ren H, Kenan DJ, Henderson BS, Keene JD, Strittmatter WJ, Burke JR. Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening. The Journal of Biological Chemistry. 275: 10437-42. PMID 10744733 DOI: 10.1074/jbc.275.14.10437  0.64
1999 Nagai Y, Onodera O, Strittmatter WJ, Burke JR. Polyglutamine domain proteins with expanded repeats bind neurofilament, altering the neurofilament network. Annals of the New York Academy of Sciences. 893: 192-202. PMID 10672238  0.64
1999 Nagai Y, Onodera O, Chun J, Strittmatter WJ, Burke JR. Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network. Experimental Neurology. 155: 195-203. PMID 10072295 DOI: 10.1006/exnr.1998.6991  0.64
1999 Cooper AJ, Sheu KF, Burke JR, Strittmatter WJ, Gentile V, Peluso G, Blass JP. Pathogenesis of inclusion bodies in (CAG)n/Qn-expansion diseases with special reference to the role of tissue transglutaminase and to selective vulnerability. Journal of Neurochemistry. 72: 889-99. PMID 10037459 DOI: 10.1046/j.1471-4159.1999.0720889.x  0.64
1999 Moulder KL, Onodera O, Burke JR, Strittmatter WJ, Johnson EM. Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 705-15. PMID 9880591  0.64
1998 Cooper AJ, Sheu KF, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly-Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions? Age. 21: 25-30. PMID 23604331 DOI: 10.1007/s11357-998-0004-x  0.64
1998 Cooper AJ, Sheu KF, Burke JR, Strittmatter WJ, Blass JP. Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts. Developmental Neuroscience. 20: 462-8. PMID 9778585 DOI: 10.1159/000017344  0.64
1998 Fullerton SM, Strittmatter WJ, Matthew WD. Peripheral sensory nerve defects in apolipoprotein E knockout mice. Experimental Neurology. 153: 156-63. PMID 9743578 DOI: 10.1006/exnr.1998.6872  0.64
1998 Scott BL, Welch K, deSerrano V, Moss NC, Roses AD, Strittmatter WJ. Human apolipoprotein E accelerates microtubule polymerization in vitro. Neuroscience Letters. 245: 105-8. PMID 9605496 DOI: 10.1016/S0304-3940(98)00180-3  0.64
1998 Guyton JR, Miller SE, Martin ME, Khan WA, Roses AD, Strittmatter WJ. Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid. Journal of Neurochemistry. 70: 1235-40. PMID 9489746  0.64
1998 Cooper AJL, Sheu KFR, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly- Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions? Age. 21: 25-30.  0.64
1997 Cooper AJ, Sheu KR, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. Proceedings of the National Academy of Sciences of the United States of America. 94: 12604-9. PMID 9356496 DOI: 10.1073/pnas.94.23.12604  0.64
1997 Tardiff BE, Newman MF, Saunders AM, Strittmatter WJ, Blumenthal JA, White WD, Croughwell ND, Davis RD, Roses AD, Reves JG. Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. The Annals of Thoracic Surgery. 64: 715-20. PMID 9307463 DOI: 10.1016/S0003-4975(97)00757-1  0.64
1997 Onodera O, Burke JR, Miller SE, Hester S, Tsuji S, Roses AD, Strittmatter WJ. Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells. Biochemical and Biophysical Research Communications. 238: 599-605. PMID 9299559 DOI: 10.1006/bbrc.1997.7337  0.64
1997 Gutman CR, Strittmatter WJ, Weisgraber KH, Matthew WD. Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6114-21. PMID 9236223  0.64
1997 Cooper AJ, Sheu KF, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases? Journal of Neurochemistry. 69: 431-4. PMID 9202340  0.64
1997 De Serrano V, Ribeiro AA, Strittmatter WJ, Spicer LD. Nmr investigation of a microtubule binding region peptide from human tau (τ) protein Protein and Peptide Letters. 4: 165-172.  0.64
1996 Strittmatter WJ, Burke JR, DeSerrano VS, Huang DY, Matthew W, Saunders AM, Scott BL, Vance JM, Weisgraber KH, Roses AD. Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases. Cold Spring Harbor Symposia On Quantitative Biology. 61: 597-605. PMID 9246486  0.64
1996 Onodera O, Roses AD, Tsuji S, Vance JM, Strittmatter WJ, Burke JR. Toxicity of expanded polyglutamine-domain proteins in Escherichia coli. Febs Letters. 399: 135-9. PMID 8980137 DOI: 10.1016/S0014-5793(96)01301-4  0.64
1996 Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer's disease. Annual Review of Neuroscience. 19: 53-77. PMID 8833436 DOI: 10.1146/annurev.ne.19.030196.000413  0.64
1996 Montine TJ, Huang DY, Valentine WM, Amarnath V, Saunders A, Weisgraber KH, Graham DG, Strittmatter WJ. Crosslinking of apolipoprotein E by products of lipid peroxidation. Journal of Neuropathology and Experimental Neurology. 55: 202-10. PMID 8786379  0.64
1996 Saunders AM, Hulette O, Welsh-Bohmer KA, Schmechel DE, Crain B, Burke JR, Alberts MJ, Strittmatter WJ, Breitner JC, Rosenberg C. Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease. Lancet (London, England). 348: 90-3. PMID 8676723 DOI: 10.1016/S0140-6736(96)01251-2  0.64
1996 Chuang DM, Ishitani R. A role for GAPDH in apoptosis and neurodegeneration. Nature Medicine. 2: 609-10. PMID 8640541 DOI: 10.1038/nm0696-609  0.64
1996 Roses AD, Einstein G, Gilbert J, Goedert M, Han SH, Huang D, Hulette C, Masliah E, Pericak-Vance MA, Saunders AM, Schmechel DE, Strittmatter WJ, Weisgraber KH, Xi PT. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Annals of the New York Academy of Sciences. 777: 146-57. PMID 8624078  0.44
1996 Fleming LM, Weisgraber KH, Strittmatter WJ, Troncoso JC, Johnson GV. Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins. Experimental Neurology. 138: 252-60. PMID 8620924 DOI: 10.1006/exnr.1996.0064  0.64
1996 Burke JR, Enghild JJ, Martin ME, Jou YS, Myers RM, Roses AD, Vance JM, Strittmatter WJ. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nature Medicine. 2: 347-50. PMID 8612237  0.64
1996 Montine TJ, Amarnath V, Martin ME, Strittmatter WJ, Graham DG. E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. The American Journal of Pathology. 148: 89-93. PMID 8546230  0.64
1995 Roses AD, Saunders AM, Alberts MA, Strittmatter WJ, Schmechel D, Gorder E, Pericak-Vance MA. Apolipoprotein E E4 allele and risk of dementia. Jama. 273: 374-5; author reply . PMID 7823377 DOI: 10.1001/jama.1995.03520290026015  0.64
1995 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Roses AD, Pericak-Vance MA, Small GW, Haines JL. The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. Jama. 273: 373-4. PMID 7823376 DOI: 10.1001/jama.1995.03520290025013  0.64
1995 Roses AD, Saunders AM, Strittmatter WJ, Schmechel DE, Pericak-Vance MA, Hyman B. Apolipoprotein E in Creutzfeldt-Jacob disease. Lancet. 345: 69. PMID 7799733  0.64
1995 Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 92: 4725-7. PMID 7761390 DOI: 10.1073/pnas.92.11.4725  0.64
1995 Alberts MJ, Graffagnino C, McClenny C, DeLong D, Strittmatter W, Saunders AM, Roses AD. ApoE genotype and survival from intracerebral haemorrhage. Lancet. 346: 575. PMID 7658797 DOI: 10.1016/S0140-6736(95)91411-0  0.64
1995 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmler JB, Locke PA, Conneally PM, Schmader KE, Tanzi RE. Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology. 45: 1323-8. PMID 7617191  0.64
1995 Huang DY, Weisgraber KH, Goedert M, Saunders AM, Roses AD, Strittmatter WJ. ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neuroscience Letters. 192: 209-12. PMID 7566652 DOI: 10.1016/0304-3940(95)11649-H  0.64
1995 Huang DY, Weisgraber KH, Strittmatter WJ, Matthew WD. Interaction of apolipoprotein E with laminin increases neuronal adhesion and alters neurite morphology. Experimental Neurology. 136: 251-7. PMID 7498414 DOI: 10.1006/exnr.1995.1101  0.64
1994 Strittmatter WJ, Weisgraber KH, Goedert M, Saunders AM, Huang D, Corder EH, Dong LM, Jakes R, Alberts MJ, Gilbert JR. Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Experimental Neurology. 125: 163-71; discussion 1. PMID 8313935 DOI: 10.1006/exnr.1994.1019  0.64
1994 Roses AD, Pericak-Vance MA, Saunders AM, Schmechel D, Goldgaber D, Strittmatter W. Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy? Epilepsia. 35: S20-8. PMID 8293721  0.64
1994 St George-Hyslop P, McLachlan DC, Tsuda T, Rogaev E, Karlinsky H, Lippa CF, Pollen D, Tuda T. Alzheimer's disease and possible gene interaction. Science (New York, N.Y.). 263: 537. PMID 8290965  0.64
1994 Whitson JS, Mims MP, Strittmatter WJ, Yamaki T, Morrisett JD, Appel SH. Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E. Biochemical and Biophysical Research Communications. 199: 163-70. PMID 8123007 DOI: 10.1006/bbrc.1994.1209  0.64
1994 Han SH, Einstein G, Weisgraber KH, Strittmatter WJ, Saunders AM, Pericak-Vance M, Roses AD, Schmechel DE. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. Journal of Neuropathology and Experimental Neurology. 53: 535-44. PMID 8083695  0.64
1994 Schwarzman AL, Gregori L, Vitek MP, Lyubski S, Strittmatter WJ, Enghilde JJ, Bhasin R, Silverman J, Weisgraber KH, Coyle PK. Transthyretin sequesters amyloid beta protein and prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 91: 8368-72. PMID 8078889  0.64
1994 Han SH, Hulette C, Saunders AM, Einstein G, Pericak-Vance M, Strittmatter WJ, Roses AD, Schmechel DE. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Experimental Neurology. 128: 13-26. PMID 8070517 DOI: 10.1006/exnr.1994.1108  0.64
1994 Weisgraber KH, Roses AD, Strittmatter WJ. The role of apolipoprotein E in the nervous system. Current Opinion in Lipidology. 5: 110-6. PMID 8044413  0.64
1994 Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. The Journal of Clinical Investigation. 94: 860-9. PMID 8040342 DOI: 10.1172/JCI117407  0.64
1994 Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, Huang DY, Pericak-Vance M, Schmechel D, Roses AD. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 11183-6. PMID 7972031  0.64
1994 Goedert M, Strittmatter WJ, Roses AD. Alzheimer's disease. Risky apolipoprotein in brain. Nature. 372: 45-6. PMID 7969418 DOI: 10.1038/372045a0  0.64
1994 Corder EH, Saunders AM, Risch NJ, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmler JB, Locke PA, Conneally PM, Schmader KE. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genetics. 7: 180-4. PMID 7920638 DOI: 10.1038/ng0694-180  0.64
1994 Roses AD, Strittmatter WJ, Pericak-Vance MA, Corder EH, Saunders AM, Schmechel DE. Clinical application of apolipoprotein E genotyping to Alzheimer's disease. Lancet. 343: 1564-5. PMID 7911881  0.64
1994 Huang DY, Goedert M, Jakes R, Weisgraber KH, Garner CC, Saunders AM, Pericak-Vance MA, Schmechel DE, Roses AD, Strittmatter WJ. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neuroscience Letters. 182: 55-8. PMID 7891887 DOI: 10.1016/0304-3940(94)90204-6  0.64
1994 Roses AD, Saunders AM, Alberts MJ, Strittmatter WJ, Schmechel DE. Re: Apolipoprotein E ε4 Neurology. 44: 2421.  0.64
1993 Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 1977-81. PMID 8446617  0.64
1993 Schmechel DE, Saunders AM, Strittmatter WJ, Crain BJ, Hulette CM, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 9649-53. PMID 8415756  0.64
1993 Strittmatter WJ, Huang DY, Bhasin R, Roses AD, Goldgaber D. Avid binding of beta A amyloid peptide to its own precursor. Experimental Neurology. 122: 327-34. PMID 8405269 DOI: 10.1006/exnr.1993.1132  0.64
1993 Strittmatter WJ, Weisgraber KH, Huang DY, Dong LM, Salvesen GS, Pericak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 8098-102. PMID 8367470  0.64
1993 Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Alberts MJ. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43: 1467-72. PMID 8350998  0.64
1993 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science (New York, N.Y.). 261: 921-3. PMID 8346443  0.64
1993 Goldgaber D, Schwarzman AI, Bhasin R, Gregori L, Schmechel D, Saunders AM, Roses AD, Strittmatter WJ. Sequestration of amyloid beta-peptide. Annals of the New York Academy of Sciences. 695: 139-43. PMID 8239272 DOI: 10.1111/j.1749-6632.1993.tb23042.x  0.64
1993 Huang D, Martin M, Hu D, Roses AD, Goldgaber D, Strittmatter WJ. Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding. Journal of Neuroimmunology. 48: 199-203. PMID 8227317 DOI: 10.1016/0165-5728(93)90192-2  0.64
1993 Saunders AM, Schmader K, Breitner JC, Benson MD, Brown WT, Goldfarb L, Goldgaber D, Manwaring MG, Szymanski MH, McCown N. Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet. 342: 710-1. PMID 8103823 DOI: 10.1016/0140-6736(93)91709-U  0.64
1992 Roses A, Alberts M, Strittmatter W. Alzheimer's disease - reassessing the data Current Biology. 2: 7-9. DOI: 10.1016/0960-9822(92)90400-5  0.64
1991 Lennarz WJ, Strittmatter WJ. Cellular functions of metallo-endoproteinases. Biochimica Et Biophysica Acta. 1071: 149-58. PMID 1854793 DOI: 10.1016/0304-4157(91)90022-O  0.64
1990 Rolak LA, Gilmer W, Strittmatter WJ. Low yield in the diagnostic evaluation of transient ischemic attacks. Neurology. 40: 747-8. PMID 2109842  0.64
1989 Roe JL, Park HR, Strittmatter WJ, Lennarz WJ. Inhibitors of metalloendoproteases block spiculogenesis in sea urchin primary mesenchyme cells. Experimental Cell Research. 181: 542-50. PMID 2924802 DOI: 10.1016/0014-4827(89)90110-9  0.64
1989 Appel SH, McManaman JL, Strittmatter WJ. Will neurotrophic agents be harmful in Alzheimer's disease? Neurobiology of Aging. 10: 580-1; discussion 58. PMID 2812232 DOI: 10.1016/0197-4580(89)90136-X  0.64
1989 Pirozzolo FJ, Inbody SB, Sims PA, Strittmatter WJ, Baskin D. Neuropathological and neuropsychological changes in Alzheimer's disease. Relationship of biologic markers to behavioral markers. Clinics in Geriatric Medicine. 5: 425-40. PMID 2680026  0.64
1988 Roe JL, Farach HA, Strittmatter WJ, Lennarz WJ. Evidence for involvement of metalloendoproteases in a step in sea urchin gamete fusion. The Journal of Cell Biology. 107: 539-44. PMID 3417761  0.64
1988 Strittmatter WJ. Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system. Cellular and Molecular Neurobiology. 8: 19-25. PMID 3042141 DOI: 10.1007/BF00712907  0.64
1988 Terrian DM, Johnston D, Claiborne BJ, Ansah-Yiadom R, Strittmatter WJ, Rea MA. Glutamate and dynorphin release from a subcellular fraction enriched in hippocampal mossy fiber synaptosomes. Brain Research Bulletin. 21: 343-51. PMID 2905627 DOI: 10.1016/0361-9230(88)90146-3  0.64
1987 Farach HA, Mundy DI, Strittmatter WJ, Lennarz WJ. Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm. The Journal of Biological Chemistry. 262: 5483-7. PMID 3553177  0.64
1987 Mundy D, Hermann T, Strittmatter WJ. Specific inhibitors implicate a soluble metalloendoproteinase in exocytosis. Cellular and Molecular Neurobiology. 7: 425-37. PMID 3330469 DOI: 10.1007/BF00733794  0.64
1987 Farach HA, Strittmatter WJ. The soluble metalloendoprotease required in myoblast fusion remains intracellular. Biochemical and Biophysical Research Communications. 147: 474-8. PMID 3307780 DOI: 10.1016/S0006-291X(87)80145-6  0.64
1985 Mundy DI, Strittmatter WJ. Requirement for metalloendoprotease in exocytosis: evidence in mast cells and adrenal chromaffin cells. Cell. 40: 645-56. PMID 2578889 DOI: 10.1016/0092-8674(85)90213-2  0.64
1984 Couch CB, Strittmatter WJ. Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts. The Journal of Biological Chemistry. 259: 5396-9. PMID 6371004  0.64
1984 Frederick JM, Hollyfield JG, Strittmatter WJ. Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 3112-9. PMID 6150072  0.64
1983 Couch CB, Strittmatter WJ. Rat myoblast fusion requires metalloendoprotease activity. Cell. 32: 257-65. PMID 6337722 DOI: 10.1016/0092-8674(83)90516-0  0.64
1983 Baxter DA, Johnston D, Strittmatter WJ. Protease inhibitors implicate metalloendoprotease in synaptic transmission at the mammalian neuromuscular junction. Proceedings of the National Academy of Sciences of the United States of America. 80: 4174-8. PMID 6306666  0.64
1981 Hirata F, Tallman JF, Henneberry RC, Mallorga P, Strittmatter WJ, Axelrod J. Phospholipid methylation: a possible mechanism of signal transduction across biomembranes. Progress in Clinical and Biological Research. 63: 383-8. PMID 6273927  0.64
1981 Strittmatter WJ, Hirata F, Axelrod J. Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. Advances in Cyclic Nucleotide Research. 14: 83-91. PMID 6269406  0.64
1980 Hirata F, Tallman JF, Henneberry RC, Mallorga P, Strittmatter WJ, Axelrod J. Regulation of beta-adrenergic receptors by phospholipid methylation. Advances in Biochemical Psychopharmacology. 21: 91-7. PMID 6246762  0.64
1979 Strittmatter WJ, Hirata F, Axelrod J. Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes. Science (New York, N.Y.). 204: 1205-7. PMID 221977  0.64
1979 Strittmatter WJ, Hirata F, Axelrod J. Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes. Biochemical and Biophysical Research Communications. 88: 147-53. PMID 156544 DOI: 10.1016/0006-291X(79)91709-1  0.64
1979 Strittmatter WJ, Hirata F, Axelrod J, Mallorga P, Tallman JF, Henneberry RC. Benzodiazepine and beta-adrenergic receptor ligands independently stimulate phospholipid methylation. Nature. 282: 857-9. PMID 42020 DOI: 10.1038/282857a0  0.64
1979 Hirata F, Strittmatter WJ, Axelrod J. beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling. Proceedings of the National Academy of Sciences of the United States of America. 76: 368-72. PMID 34151  0.64
1978 Strittmatter WJ, Gagnon C, Axelrod J. Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland. The Journal of Pharmacology and Experimental Therapeutics. 207: 419-24. PMID 712630  0.64
1977 Davis JN, Strittmatter WJ, Hoyler E, Leefkowitz RJ. [3H]dihydroergocryptine binding in rat brain. Brain Research. 132: 327-36. PMID 196714 DOI: 10.1016/0006-8993(77)90425-5  0.64
1977 Strittmatter WJ, Davis JN, Lefkowitz RJ. alpha-Adrenergic receptors in rat parotid cells. II. Desensitization of receptor binding sites and potassium release. The Journal of Biological Chemistry. 252: 5478-82. PMID 195951  0.64
1977 Strittmatter WJ, Davis JN, Lefkowitz RJ. alpha-Adrenergic receptors in rat parotid cells. I. Correlation of [3H]dihydroergocryptine binding and catecholamine-stimulated potassium efflux. The Journal of Biological Chemistry. 252: 5472-7. PMID 195950  0.64
1977 Strittmatter WJ, Davis JN, Lefkowitz RJ. α Adrenergic receptor desensitization: Reduction in physiologic response and receptor binding sites in rat parotid acinar cells Clinical Research. 25: 34A.  0.64
1977 Strittmatter WJ, Davis JN, Lefkowitz RJ. α Adrenergic receptor regulation: parallel change in K+ release and [3H]dihydroergocryptine (DHE) binding in rat parotid Federation Proceedings. 36: No.3585.  0.64
1973 Strittmatter WJ, Somjen GG. Depression of sustained evoked potentials and glial depolarization in the spinal cord by barbiturates and by diphenylhydantoin. Brain Research. 55: 333-42. PMID 4714007 DOI: 10.1016/0006-8993(73)90299-0  0.64
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