Allen D. Roses, MD - Publications

Affiliations: 
Medicine Duke University, Durham, NC 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=26
Website:
http://medicine.duke.edu/faculty/details/0098535

303 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lutz MW, Sundseth SS, Burns DK, Saunders AM, Hayden KM, Burke JR, Welsh-Bohmer KA, Roses AD. A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease. Alzheimer's & Dementia : Translational Research & Clinical Interventions. 2: 30-44. PMID 27047990 DOI: 10.1016/j.trci.2015.12.002  1
2016 Roses AD, Akkari PA, Chiba-Falek O, Lutz MW, Gottschalk WK, Saunders AM, Saul B, Sundseth S, Burns D. Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing. Expert Opinion On Drug Metabolism & Toxicology. PMID 26727306 DOI: 10.1517/17425255.2016.1133586  1
2015 Roses AD. Polyallelic structural variants can provide accurate, highly informative genetic markers focused on diagnosis and therapeutic targets: Accuracy versus precision. Clinical Pharmacology and Therapeutics. PMID 26517180 DOI: 10.1002/cpt.288  1
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/nrneurol.2015.177  1
2015 Lyall DM, Muñoz Maniega S, Harris SE, Bastin ME, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández MD, Royle NA, Starr JM, Porteous DJ, Deary IJ, Wardlaw JM. APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds. International Journal of Stroke : Official Journal of the International Stroke Society. PMID 26310205 DOI: 10.1111/ijs.12615  1
2015 Lutz MW, Saul R, Linnertz C, Glenn OC, Roses AD, Chiba-Falek O. A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 1133-43. PMID 26079410 DOI: 10.1016/j.jalz.2015.05.011  1
2015 Crenshaw DG, Asin K, Gottschalk WK, Liang Z, Zhang N, Roses AD. Effects of low doses of pioglitazone on resting-state functional connectivity in conscious rat brain. Plos One. 10: e0117973. PMID 25671601 DOI: 10.1371/journal.pone.0117973  1
2014 Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, et al. African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 592-601.e2. PMID 25260913 DOI: 10.1016/j.jalz.2014.06.009  1
2014 Lyall DM, Harris SE, Bastin ME, Muñoz Maniega S, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity? Translational Psychiatry. 4: e449. PMID 25247594 DOI: 10.1038/tp.2014.89  1
2014 Hayden KM, Makeeva OA, Newby LK, Plassman BL, Markova VV, Dunham A, Romero HR, Melikyan ZA, Germain CM, Welsh-Bohmer KA, Roses AD. A comparison of neuropsychological performance between US and Russia: preparing for a global clinical trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 760-768.e1. PMID 25066497 DOI: 10.1016/j.jalz.2014.02.008  1
2014 Greenbaum L, Springer RR, Lutz MW, Heymann A, Lubitz I, Cooper I, Kravitz E, Sano M, Roses AD, Silverman JM, Saunders AM, Beeri MS. The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1492-9. PMID 25044051 DOI: 10.1016/j.euroneuro.2014.06.002  1
2014 Linnertz C, Lutz MW, Ervin JF, Allen J, Miller NR, Welsh-Bohmer KA, Roses AD, Chiba-Falek O. The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease. Human Molecular Genetics. 23: 4814-21. PMID 24777780 DOI: 10.1093/hmg/ddu196  1
2014 Romero HR, Welsh-Bohmer KA, Gwyther LP, Edmonds HL, Plassman BL, Germain CM, McCart M, Hayden KM, Pieper C, Roses AD. Community engagement in diverse populations for Alzheimer disease prevention trials. Alzheimer Disease and Associated Disorders. 28: 269-74. PMID 24614272 DOI: 10.1097/WAD.0000000000000029  1
2014 Roses AD, Saunders AM, Lutz MW, Zhang N, Hariri AR, Asin KE, Crenshaw DG, Budur K, Burns DK, Brannan SK. New applications of disease genetics and pharmacogenetics to drug development. Current Opinion in Pharmacology. 14: 81-9. PMID 24565016 DOI: 10.1016/j.coph.2013.12.002  1
2014 Lyall DM, Harris SE, Bastin ME, Muñoz Maniega S, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936. Neurobiology of Aging. 35: 1513.e25-33. PMID 24508314 DOI: 10.1016/j.neurobiolaging.2014.01.006  1
2014 Linnertz C, Anderson L, Gottschalk W, Crenshaw D, Lutz MW, Allen J, Saith S, Mihovilovic M, Burke JR, Welsh-Bohmer KA, Roses AD, Chiba-Falek O. The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 541-51. PMID 24439168 DOI: 10.1016/j.jalz.2013.08.280  1
2014 Davies G, Harris SE, Reynolds CA, Payton A, Knight HM, Liewald DC, Lopez LM, Luciano M, Gow AJ, Corley J, Henderson R, Murray C, Pattie A, Fox HC, Redmond P, ... ... Roses AD, et al. A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. Molecular Psychiatry. 19: 76-87. PMID 23207651 DOI: 10.1038/mp.2012.159  1
2013 Lyall DM, Royle NA, Harris SE, Bastin ME, Maniega SM, Murray C, Lutz MW, Saunders AM, Roses AD, del Valdés Hernández MC, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936. Plos One. 8: e80513. PMID 24260406 DOI: 10.1371/journal.pone.0080513  1
2013 Mastaglia FL, Rojana-udomsart A, James I, Needham M, Day TJ, Kiers L, Corbett JA, Saunders AM, Lutz MW, Roses AD. Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms. Neuromuscular Disorders : Nmd. 23: 969-74. PMID 24103330 DOI: 10.1016/j.nmd.2013.09.008  1
2013 Roses AD, Lutz MW, Crenshaw DG, Grossman I, Saunders AM, Gottschalk WK. TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 132-6. PMID 23333464 DOI: 10.1016/j.jalz.2012.10.009  1
2013 Crenshaw DG, Gottschalk WK, Lutz MW, Grossman I, Saunders AM, Burke JR, Welsh-Bohmer KA, Brannan SK, Burns DK, Roses AD. Using genetics to enable studies on the prevention of Alzheimer's disease. Clinical Pharmacology and Therapeutics. 93: 177-85. PMID 23249780 DOI: 10.1038/clpt.2012.222  1
2012 Caselli RJ, Dueck AC, Huentelman MJ, Lutz MW, Saunders AM, Reiman EM, Roses AD. Longitudinal modeling of cognitive aging and the TOMM40 effect. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 490-5. PMID 23102119 DOI: 10.1016/j.jalz.2011.11.006  1
2012 Chiba-Falek O, Linnertz C, Guyton J, Gardner SD, Roses AD, McCarthy JJ, Patel K. Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection. Human Genetics. 131: 1911-20. PMID 22898894 DOI: 10.1007/s00439-012-1220-0  1
2012 Hayden KM, McEvoy JM, Linnertz C, Attix D, Kuchibhatla M, Saunders AM, Lutz MW, Welsh-Bohmer KA, Roses AD, Chiba-Falek O. A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 381-8. PMID 22863908 DOI: 10.1016/j.jalz.2011.10.005  1
2012 Linnertz C, Saunders AM, Lutz MW, Crenshaw DM, Grossman I, Burns DK, Whitfield KE, Hauser MA, McCarthy JJ, Ulmer M, Allingham R, Welsh-Bohmer KA, Roses AD, Chiba-Falek O. Characterization of the poly-T variant in the TOMM40 gene in diverse populations. Plos One. 7: e30994. PMID 22359560 DOI: 10.1371/journal.pone.0030994  1
2011 Johnson SC, La Rue A, Hermann BP, Xu G, Koscik RL, Jonaitis EM, Bendlin BB, Hogan KJ, Roses AD, Saunders AM, Lutz MW, Asthana S, Green RC, Sager MA. The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 456-65. PMID 21784354 DOI: 10.1016/j.jalz.2010.11.012  1
2011 Pomara N, Bruno D, Sidtis JJ, Lutz MW, Greenblatt DJ, Saunders AM, Roses AD. Translocase of outer mitochondrial membrane 40 homolog (TOMM40) poly-T length modulates lorazepam-related cognitive toxicity in healthy APOE ε4-negative elderly. Journal of Clinical Psychopharmacology. 31: 544-6. PMID 21720235 DOI: 10.1097/JCP.0b013e318222810e  1
2011 Lutz MW, Crenshaw DG, Saunders AM, Roses AD. The importance of being connected. Journal of Alzheimer's Disease : Jad. 24: 247-51. PMID 21206004 DOI: 10.3233/JAD-2010-101765  1
2010 Grossman I, Lutz MW, Crenshaw DG, Saunders AM, Burns DK, Roses AD. Alzheimer's disease: diagnostics, prognostics and the road to prevention. The Epma Journal. 1: 293-303. PMID 21124753 DOI: 10.1007/s13167-010-0024-3  1
2010 Khachaturian AS, Chapman J, Farrer L, Friedland RP, Ebstein R, Grossman I, Hendler T, Hermann B, Inzelberg R, Johnson S, Khachaturian ZS, Lichter-Shapira I, Makeeva O, Mayrl R, Mizrahi E, ... Roses AD, et al. Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 475-81. PMID 21044777 DOI: 10.1016/j.jalz.2010.10.001  1
2010 Roses AD. An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease. Archives of Neurology. 67: 536-41. PMID 20457951 DOI: 10.1001/archneurol.2010.88  1
2010 Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Genetic variation at a single locus and age of onset for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 125-31. PMID 20298972 DOI: 10.1016/j.jalz.2010.01.011  1
2010 Heinzen EL, Need AC, Hayden KM, Chiba-Falek O, Roses AD, Strittmatter WJ, Burke JR, Hulette CM, Welsh-Bohmer KA, Goldstein DB. Genome-wide scan of copy number variation in late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 69-77. PMID 20061627 DOI: 10.3233/JAD-2010-1212  1
2010 Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, Huentelman MJ, Welsh-Bohmer KA, Reiman EM. A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease. The Pharmacogenomics Journal. 10: 375-84. PMID 20029386 DOI: 10.1038/tpj.2009.69  1
2010 Muglia P, Tozzi F, Galwey NW, Francks C, Upmanyu R, Kong XQ, Antoniades A, Domenici E, Perry J, Rothen S, Vandeleur CL, Mooser V, Waeber G, Vollenweider P, Preisig M, ... ... Roses AD, et al. Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. Molecular Psychiatry. 15: 589-601. PMID 19107115 DOI: 10.1038/mp.2008.131  1
2010 Makeeva OA, Markova VV, Roses AD, Puzyrev VP. An epidemiologic-based survey of public attitudes towards predictive genetic testing in Russia Personalized Medicine. 7: 291-300. DOI: 10.2217/pme.10.23  1
2009 Akkari PA, Swanson TW, Crenshaw DG, Grossman I, Sundseth S, Burns DK, Roses AD. Pipeline pharmacogenetics: a novel approach to integrating pharmaco-genetics into drug development. Current Pharmaceutical Design. 15: 3754-63. PMID 19925426 DOI: 10.2174/138161209789649538  1
2009 Scott LJ, Muglia P, Kong XQ, Guan W, Flickinger M, Upmanyu R, Tozzi F, Li JZ, Burmeister M, Absher D, Thompson RC, Francks C, Meng F, Antoniades A, Southwick AM, ... ... Roses AD, et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America. 106: 7501-6. PMID 19416921 DOI: 10.1073/pnas.0813386106  1
2009 Roses AD. Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clinical Pharmacology and Therapeutics. 85: 362-5. PMID 19295535 DOI: 10.1038/clpt.2008.192  1
2009 Need AC, Ge D, Weale ME, Maia J, Feng S, Heinzen EL, Shianna KV, Yoon W, KasperaviciÅ«te D, Gennarelli M, Strittmatter WJ, Bonvicini C, Rossi G, Jayathilake K, Cola PA, ... ... Roses AD, et al. A genome-wide investigation of SNPs and CNVs in schizophrenia. Plos Genetics. 5: e1000373. PMID 19197363 DOI: 10.1371/journal.pgen.1000373  1
2009 Lin X, Song K, Lim N, Yuan X, Johnson T, Abderrahmani A, Vollenweider P, Stirnadel H, Sundseth SS, Lai E, Burns DK, Middleton LT, Roses AD, Matthews PM, Waeber G, et al. Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Diabetologia. 52: 600-8. PMID 19139842 DOI: 10.1007/s00125-008-1254-y  1
2009 Roses AD. The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 6-17. PMID 18923406 DOI: 10.1038/npp.2008.153  1
2009 Nelson MR, Bacanu SA, Mosteller M, Li L, Bowman CE, Roses AD, Lai EH, Ehm MG. Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions. The Pharmacogenomics Journal. 9: 23-33. PMID 18301416 DOI: 10.1038/tpj.2008.4  1
2009 Spraggs CF, Koshy BT, Edbrooke MR, Roses AD. Role of Pharmacogenomics in Drug Development Genomic and Personalized Medicine, Two-Vol Set. 343-356. DOI: 10.1016/B978-0-12-369420-1.00029-9  1
2008 Cutler P, Akuffo EL, Bodnar WM, Briggs DM, Davis JB, Debouck CM, Fox SM, Gibson RA, Gormley DA, Holbrook JD, Hunter AJ, Kinsey EE, Prinjha R, Richardson JC, Roses AD, et al. Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium-derived factor: Two novel biomarkers of Alzheimer's disease in human plasma. Proteomics. Clinical Applications. 2: 467-77. PMID 21136851 DOI: 10.1002/prca.200780101  1
2008 Akuffo EL, Davis JB, Fox SM, Gloger IS, Hosford D, Kinsey EE, Jones NA, Nock CM, Roses AD, Saunders AM, Skehel JM, Smith MA, Cutler P. The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 13: 618-36. PMID 18830857 DOI: 10.1080/13547500802445199  1
2008 Roses AD. Pharmacogenetics in drug discovery and development: a translational perspective. Nature Reviews. Drug Discovery. 7: 807-17. PMID 18806753 DOI: 10.1038/nrd2593  1
2008 Nelson MR, Bryc K, King KS, Indap A, Boyko AR, Novembre J, Briley LP, Maruyama Y, Waterworth DM, Waeber G, Vollenweider P, Oksenberg JR, Hauser SL, Stirnadel HA, Kooner JS, ... ... Roses AD, et al. The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. American Journal of Human Genetics. 83: 347-58. PMID 18760391 DOI: 10.1016/j.ajhg.2008.08.005  1
2008 Roses AD. Commentary on "a roadmap for the prevention of dementia: the inaugural Leon Thal Symposium." An impending prevention clinical trial for Alzheimer's disease: roadmaps and realities. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 4: 164-6. PMID 18631961 DOI: 10.1016/j.jalz.2008.03.007  1
2008 Cogswell JP, Ward J, Taylor IA, Waters M, Shi Y, Cannon B, Kelnar K, Kemppainen J, Brown D, Chen C, Prinjha RK, Richardson JC, Saunders AM, Roses AD, Richards CA. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. Journal of Alzheimer's Disease : Jad. 14: 27-41. PMID 18525125  1
2008 Netzer C, Freudenberg J, Heinze A, Heinze-Kuhn K, Goebel I, McCarthy LC, Roses AD, Göbel H, Todt U, Kubisch C. Replication study of the insulin receptor gene in migraine with aura. Genomics. 91: 503-7. PMID 18455362 DOI: 10.1016/j.ygeno.2008.03.006  1
2008 Hughes AR, Spreen WR, Mosteller M, Warren LL, Lai EH, Brothers CH, Cox C, Nelsen AJ, Hughes S, Thorborn DE, Stancil B, Hetherington SV, Burns DK, Roses AD. Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility. The Pharmacogenomics Journal. 8: 365-74. PMID 18332899 DOI: 10.1038/tpj.2008.3  1
2008 Brodbeck J, Balestra ME, Saunders AM, Roses AD, Mahley RW, Huang Y. Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 1343-6. PMID 18212130 DOI: 10.1073/pnas.0709906104  1
2008 Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, ... ... Roses AD, et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Archives of Neurology. 65: 45-53. PMID 17998437 DOI: 10.1001/archneurol.2007.3  1
2008 Zhu G, Carlsen K, Carlsen KH, Lenney W, Silverman M, Whyte MK, Hosking L, Helms P, Roses AD, Hay DW, Barnes MR, Anderson WH, Pillai SG. Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations. Genes and Immunity. 9: 23-9. PMID 17960156 DOI: 10.1038/sj.gene.6364441  1
2007 Roses AD. Genome-wide screening for drug discovery and companion diagnostics. Expert Opinion On Drug Discovery. 2: 489-501. PMID 23484757 DOI: 10.1517/17460441.2.4.489  1
2007 Roses AD, St Jean PL, Ehm MG. Use of whole-genome association scans in disease gene identification, drug discovery and development. Idrugs : the Investigational Drugs Journal. 10: 797-804. PMID 17968762  1
2007 Warren LL, Hughes AR, Lai EH, Zaykin DV, Haneline SA, Bansal AT, Wooster AW, Spreen WR, Hernandez JE, Scott TR, Roses AD, Mosteller M. Use of pairwise marker combination and recursive partitioning in a pharmacogenetic genome-wide scan. The Pharmacogenomics Journal. 7: 180-9. PMID 16969363 DOI: 10.1038/sj.tpj.6500414  1
2007 Roses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, Mahley RW. Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease). The Pharmacogenomics Journal. 7: 10-28. PMID 16770341 DOI: 10.1038/sj.tpj.6500397  1
2006 Roses AD, Saunders AM. Perspective on a pathogenesis and treatment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 59-70. PMID 19595857 DOI: 10.1016/j.jalz.2005.12.001  1
2006 Roses AD. On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease. Journal of Alzheimer's Disease : Jad. 9: 361-6. PMID 16914873  1
2006 Risner ME, Saunders AM, Altman JF, Ormandy GC, Craft S, Foley IM, Zvartau-Hind ME, Hosford DA, Roses AD. Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. The Pharmacogenomics Journal. 6: 246-54. PMID 16446752 DOI: 10.1038/sj.tpj.6500369  1
2006 Stankovich J, Cox CJ, Tan RB, Montgomery DS, Huxtable SJ, Rubio JP, Ehm MG, Johnson L, Butzkueven H, Kilpatrick TJ, Speed TP, Roses AD, Bahlo M, Foote SJ. On the utility of data from the International HapMap Project for Australian association studies. Human Genetics. 119: 220-2. PMID 16404587 DOI: 10.1007/s00439-005-0120-y  1
2005 Liu C, Ghosh S, Searls DB, Saunders AM, Cossman J, Roses AD. Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery. Omics : a Journal of Integrative Biology. 9: 351-63. PMID 16402893 DOI: 10.1089/omi.2005.9.351  1
2005 Spraggs CF, Pillai SG, Dow D, Douglas C, McCarthy L, Manasco PK, Stubbins M, Roses AD. Pharmacogenetics and obesity: common gene variants influence weight loss response of the norepinephrine/dopamine transporter inhibitor GW320659 in obese subjects. Pharmacogenetics and Genomics. 15: 883-9. PMID 16272960  1
2005 Roses AD. Applying technologies towards safe and effective medicines. Biotechniques. 39: 563-4. PMID 16235568 DOI: 10.2144/000112042  1
2005 Roses AD, Burns DK, Chissoe S, Middleton L, St Jean P. Disease-specific target selection: a critical first step down the right road. Drug Discovery Today. 10: 177-89. PMID 15708532 DOI: 10.1016/S1359-6446(04)03321-5  1
2005 Ahmadi KR, Weale ME, Xue ZY, Soranzo N, Yarnall DP, Briley JD, Maruyama Y, Kobayashi M, Wood NW, Spurr NK, Burns DK, Roses AD, Saunders AM, Goldstein DB. A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nature Genetics. 37: 84-9. PMID 15608640 DOI: 10.1038/ng1488  1
2005 Ahmadi KR, Weale ME, Roses AD, Saunders AM, Goldstein DB. In reply [2] Nature Genetics. 37: 916. DOI: 10.1038/ng0905-916  1
2004 Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA, Martin ER. Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. Neurogenetics. 5: 201-8. PMID 15455263 DOI: 10.1007/s10048-004-0189-9  1
2004 Roses AD. Pharmacogenetics and drug development: the path to safer and more effective drugs. Nature Reviews. Genetics. 5: 645-56. PMID 15372086 DOI: 10.1038/nrg1432  1
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, ... ... Roses AD, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/ng0904-921  1
2004 Xu CF, Lewis KF, Yeo AJ, McCarthy LC, Maguire MF, Anwar Z, Danoff TM, Roses AD, Purvis IJ. Identification of a pharmacogenetic effect by linkage disequilibrium mapping. The Pharmacogenomics Journal. 4: 374-8. PMID 15303110 DOI: 10.1038/sj.tpj.6500268  1
2004 Hauser ER, Crossman DC, Granger CB, Haines JL, Jones CJ, Mooser V, McAdam B, Winkelmann BR, Wiseman AH, Muhlestein JB, Bartel AG, Dennis CA, Dowdy E, Estabrooks S, Eggleston K, ... ... Roses AD, et al. A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. American Journal of Human Genetics. 75: 436-47. PMID 15272420 DOI: 10.1086/423900  1
2004 van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, Welsh-Bohmer KA, Saunders AM, Roses AD, Small GW, Schmechel DE, Murali Doraiswamy P, Gilbert JR, Haines JL, Vance JM, et al. Analysis of European mitochondrial haplogroups with Alzheimer disease risk. Neuroscience Letters. 365: 28-32. PMID 15234467 DOI: 10.1016/j.neulet.2004.04.051  1
2004 Hosford DA, Lai EH, Riley JH, Xu CF, Danoff TM, Roses AD. Pharmacogenetics to predict drug-related adverse events. Toxicologic Pathology. 32: 9-12. PMID 15209398  1
2004 North BV, Curtis D, Martin ER, Lai EH, Roses AD, Sham PC. Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci. Annals of Human Genetics. 68: 240-8. PMID 15180704 DOI: 10.1046/j.1529-8817.2004.00086.x  1
2004 Rose AD. Allen D. Rose. Nature Reviews. Drug Discovery. 3: 382. PMID 15152630 DOI: 10.1038/nrd1400  1
2004 Hughes AR, Mosteller M, Bansal AT, Davies K, Haneline SA, Lai EH, Nangle K, Scott T, Spreen WR, Warren LL, Roses AD. Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations. Pharmacogenomics. 5: 203-11. PMID 15016610 DOI: 10.1517/phgs.5.2.203.27481  1
2004 Danoff TM, Campbell DA, McCarthy LC, Lewis KF, Repasch MH, Saunders AM, Spurr NK, Purvis IJ, Roses AD, Xu CF. A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. The Pharmacogenomics Journal. 4: 49-53. PMID 14647407 DOI: 10.1038/sj.tpj.6500221  1
2004 Roses AD. Applying pharmacogenetics in drug development Drug Development Research. 62: 79-80. DOI: 10.1002/ddr.10369  1
2003 Li YJ, Oliveira SA, Xu P, Martin ER, Stenger JE, Scherzer CR, Hauser MA, Scott WK, Small GW, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, ... ... Roses AD, et al. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Human Molecular Genetics. 12: 3259-67. PMID 14570706 DOI: 10.1093/hmg/ddg357  1
2003 Scott WK, Hauser ER, Schmechel DE, Welsh-Bohmer KA, Small GW, Roses AD, Saunders AM, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22. American Journal of Human Genetics. 73: 1041-51. PMID 14564669 DOI: 10.1086/379083  1
2003 Ezra Y, Oron L, Moskovich L, Roses AD, Beni SM, Shohami E, Michaelson DM. Apolipoprotein E4 decreases whereas apolipoprotein E3 increases the level of secreted amyloid precursor protein after closed head injury. Neuroscience. 121: 315-25. PMID 14521991 DOI: 10.1016/S0306-4522(03)00436-6  1
2003 Schmith VD, Campbell DA, Sehgal S, Anderson WH, Burns DK, Middleton LT, Roses AD. Pharmacogenetics and disease genetics of complex diseases. Cellular and Molecular Life Sciences : Cmls. 60: 1636-46. PMID 14504654 DOI: 10.1007/s00018-003-2369-4  1
2003 Levi O, Jongen-Relo AL, Feldon J, Roses AD, Michaelson DM. ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory. Neurobiology of Disease. 13: 273-82. PMID 12901842 DOI: 10.1016/S0969-9961(03)00045-7  1
2003 Oliveira SA, Martin ER, Scott WK, Nicodemus KK, Small GW, Schmechel DE, Doraiswamy PM, Roses AD, Saunders AM, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA. The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease. Neuroscience Letters. 347: 143-6. PMID 12875906 DOI: 10.1016/S0304-3940(03)00670-0  1
2003 Norbert PW, Roses AD. Pharmacogenetics and pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications. Journal of Molecular Medicine (Berlin, Germany). 81: 135-40. PMID 12755119  1
2003 van der Walt JM, Martin ER, Scott WK, Zhang F, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, ... ... Roses AD, et al. Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. Neurology. 60: 1189-91. PMID 12682333  1
2003 Hauser ER, Mooser V, Crossman DC, Haines JL, Jones CH, Winkelmann BR, Schmidt S, Scott WK, Roses AD, Pericak-Vance MA, Granger CB, Kraus WE. Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study. American Heart Journal. 145: 602-13. PMID 12679755 DOI: 10.1067/mhj.2003.13  1
2003 Roses AD, Pangalos MN. Drug development and Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 11: 123-30. PMID 12611742 DOI: 10.1097/00019442-200303000-00003  1
2003 Roses AD. The genome era begins.. Nature Genetics. 33: 217. DOI: 10.1038/ng1110  1
2002 Roses AD. SNPs--where's the beef? The Pharmacogenomics Journal. 2: 277-83. PMID 12439733 DOI: 10.1038/sj.tpj.6500126  1
2002 Lai E, Bowman C, Bansal A, Hughes A, Mosteller M, Roses AD. Medical applications of haplotype-based SNP maps: learning to walk before we run. Nature Genetics. 32: 353. PMID 12410232 DOI: 10.1038/ng1102-353  1
2002 Roses AD. Genome-based pharmacogenetics and the pharmaceutical industry. Nature Reviews. Drug Discovery. 1: 541-9. PMID 12120260 DOI: 10.1038/nrd840  1
2002 Teter B, Xu PT, Gilbert JR, Roses AD, Galasko D, Cole GM. Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function. Journal of Neuroscience Research. 68: 331-6. PMID 12111863 DOI: 10.1002/jnr.10221  1
2002 Hetherington S, Hughes AR, Mosteller M, Shortino D, Baker KL, Spreen W, Lai E, Davies K, Handley A, Dow DJ, Fling ME, Stocum M, Bowman C, Thurmond LM, Roses AD. Genetic variations in HLA-B region and hypersensitivity reactions to abacavir. Lancet. 359: 1121-2. PMID 11943262 DOI: 10.1016/S0140-6736(02)08158-8  1
2002 Roses AD. Pharmacogenetics place in modern medical science and practice. Life Sciences. 70: 1471-80. PMID 11895098 DOI: 10.1016/S0024-3205(01)01532-6  1
2002 Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA, Goetz CG, ... ... Roses AD, et al. Age at onset in two common neurodegenerative diseases is genetically controlled. American Journal of Human Genetics. 70: 985-93. PMID 11875758 DOI: 10.1086/339815  1
2001 McCarthy LC, Hosford DA, Riley JH, Bird MI, White NJ, Hewett DR, Peroutka SJ, Griffiths LR, Boyd PR, Lea RA, Bhatti SM, Hosking LK, Hood CM, Jones KW, Handley AR, ... ... Roses AD, et al. Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine. Genomics. 78: 135-49. PMID 11735220 DOI: 10.1006/geno.2001.6647  1
2001 Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Goetz CG, ... ... Roses AD, et al. Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. Jama. 286: 2245-50. PMID 11710889  1
2001 Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Goetz CG, Small GW, ... ... Roses AD, et al. Complete genomic screen in Parkinson disease: evidence for multiple genes. Jama. 286: 2239-44. PMID 11710888  1
2001 Roses AD. 2025: the practice of neurology: back from the future. Archives of Neurology. 58: 1766-7. PMID 11708982  1
2001 Roses AD. Pharmacogenetics. Human Molecular Genetics. 10: 2261-7. PMID 11673409  1
2001 White F, Nicoll JA, Roses AD, Horsburgh K. Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion. Neurobiology of Disease. 8: 611-25. PMID 11493026 DOI: 10.1006/nbdi.2001.0401  1
2001 Roses AD. How will pharmacogenetics impact the future of research and development? Drug Discovery Today. 6: 59-60. PMID 11166244 DOI: 10.1016/S1359-6446(00)01609-3  1
2000 Horsburgh K, McCulloch J, Nilsen M, Roses AD, Nicoll JA. Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia. The European Journal of Neuroscience. 12: 4309-17. PMID 11122341 DOI: 10.1046/j.1460-9568.2000.01339.x  1
2000 Pericak-Vance MA, Grubber J, Bailey LR, Hedges D, West S, Santoro L, Kemmerer B, Hall JL, Saunders AM, Roses AD, Small GW, Scott WK, Conneally PM, Vance JM, Haines JL. Identification of novel genes in late-onset Alzheimer's disease. Experimental Gerontology. 35: 1343-52. PMID 11113612 DOI: 10.1016/S0531-5565(00)00196-0  1
2000 Sabo T, Lomnitski L, Nyska A, Beni S, Maronpot RR, Shohami E, Roses AD, Michaelson DM. Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities. Neuroscience. 101: 879-84. PMID 11113336 DOI: 10.1016/S0306-4522(00)00438-3  1
2000 Roses AD. Idiosyncratic reactions to drugs: can medicine response profiles provide a dynamic drug surveillance system? Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 38: 815-8. PMID 11097333 DOI: 10.1515/CCLM.2000.117  1
2000 Roses AD. Pharmacogenetics and pharmacogenomics in the discovery and development of medicines. Novartis Foundation Symposium. 229: 63-6; discussion 66-. PMID 11084930  1
2000 Roses AD. Genetic susceptibility to cardiovascular diseases. American Heart Journal. 140: S45-7. PMID 11011323 DOI: 10.1067/mhj.2000.108471  1
2000 Wilkins MR, Roses AD, Clifford CP. Pharmacogenetics and the treatment of cardiovascular disease. Heart (British Cardiac Society). 84: 353-4. PMID 10995394  1
2000 Saunders AM, Trowers MK, Shimkets RA, Blakemore S, Crowther DJ, Mansfield TA, Wallace DM, Strittmatter WJ, Roses AD. The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. Biochimica Et Biophysica Acta. 1502: 85-94. PMID 10899434 DOI: 10.1016/S0925-4439(00)00035-1  1
2000 Martin ER, Lai EH, Gilbert JR, Rogala AR, Afshari AJ, Riley J, Finch KL, Stevens JF, Livak KJ, Slotterbeck BD, Slifer SH, Warren LL, Conneally PM, Schmechel DE, Purvis I, ... ... Roses AD, et al. SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. American Journal of Human Genetics. 67: 383-94. PMID 10869235 DOI: 10.1086/303003  1
2000 Roses AD. Pharmacogenetics and the practice of medicine. Nature. 405: 857-65. PMID 10866212 DOI: 10.1038/35015728  1
2000 Roses AD. Causes or consequences of inflammation and pathological signs of Alzheimer disease. Neurobiology of Aging. 21: 423-5. PMID 10858587 DOI: 10.1016/S0197-4580(00)00142-1  1
2000 Chapman S, Sabo T, Roses AD, Michaelson DM. Reversal of presynaptic deficits of apolipoprotein E-deficient mice in human apolipoprotein E transgenic mice. Neuroscience. 97: 419-24. PMID 10828524 DOI: 10.1016/S0306-4522(00)00087-7  1
2000 Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, Wu HM, Mega MS, Cummings JL, ... ... Roses AD, et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 6037-42. PMID 10811879 DOI: 10.1073/pnas.090106797  1
2000 Mounsey JP, John JE, Helmke SM, Bush EW, Gilbert J, Roses AD, Perryman MB, Jones LR, Moorman JR. Phospholemman is a substrate for myotonic dystrophy protein kinase. The Journal of Biological Chemistry. 275: 23362-7. PMID 10811636 DOI: 10.1074/jbc.M000899200  1
2000 Riley KP, Snowdon DA, Saunders AM, Roses AD, Mortimer JA, Nanayakkara N. Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences. 55: S69-75. PMID 10794191  1
2000 Roses AD. Pharmacogenetics and future drug development and delivery. Lancet. 355: 1358-61. PMID 10776762 DOI: 10.1016/S0140-6736(00)02126-7  1
2000 Ashizawa T, Gonzales I, Ohsawa N, Singer RH, Devillers M, Balasubramanyam A, Cooper TA, Khajavi M, Lia-Baldini AS, Miller G, Philips AV, Timchenko LT, Waring J, Yamagata H, Barbet JP, ... ... Roses AD, et al. New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1) Neurology. 54: 1218-1221. PMID 10746587  1
2000 Horsburgh K, McCulloch J, Nilsen M, McCracken E, Large C, Roses AD, Nicoll JA. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 458-62. PMID 10724109 DOI: 10.1097/00004647-200003000-00003  1
2000 Scott WK, Grubber JM, Conneally PM, Small GW, Hulette CM, Rosenberg CK, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. American Journal of Human Genetics. 66: 922-32. PMID 10712207 DOI: 10.1086/302828  1
2000 Martin ER, Gilbert JR, Lai EH, Riley J, Rogala AR, Slotterbeck BD, Sipe CA, Grubber JM, Warren LL, Conneally PM, Saunders AM, Schmechel DE, Purvis I, Pericak-Vance MA, Roses AD, et al. Analysis of association at single nucleotide polymorphisms in the APOE region. Genomics. 63: 7-12. PMID 10662539 DOI: 10.1006/geno.1999.6057  1
2000 Grubber JM, Saunders AM, Yamaoka LH, Scott WK, Martin ER, Hill DM, Standen CL, Michael Conneally P, Small GW, Lai EH, Gilbert JR, Roses AD, Haines JL, Pericak-Vance MA. Analysis of chromosome 12 candidate genes in late-onset Alzheimer disease Alzheimer's Reports. 3: 221-226.  1
1999 Boschert U, Merlo-Pich E, Higgins G, Roses AD, Catsicas S. Apolipoprotein E expression by neurons surviving excitotoxic stress. Neurobiology of Disease. 6: 508-14. PMID 10600406 DOI: 10.1006/nbdi.1999.0251  1
1999 Teter B, Xu PT, Gilbert JR, Roses AD, Galasko D, Cole GM. Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture. Journal of Neurochemistry. 73: 2613-6. PMID 10582625 DOI: 10.1046/j.1471-4159.1999.0732613.x  1
1999 Scott WK, Yamaoka LH, Stajich JM, Scott BL, Vance JM, Roses AD, Pericak-Vance MA, Watts RL, Nance M, Hubble J, Koller W, Stern MB, Colcher A, Allen FH, Hiner BC, et al. The alpha-synuclein gene is not a major risk factor in familial Parkinson disease. Neurogenetics. 2: 191-2. PMID 10541595 DOI: 10.1007/s100480050083  1
1999 Small GW, Scott WK, Komo S, Yamaoka LH, Farrer LA, Auerbach SH, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics. 2: 177-82. PMID 10541592 DOI: 10.1007/s100480050080  1
1999 Hulette CM, Pericak-Vance MA, Roses AD, Schmechel DE, Yamaoka LH, Gaskell PC, Welsh-Bohmer KA, Crowther RA, Spillantini MG. Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684. Journal of Neuropathology and Experimental Neurology. 58: 859-66. PMID 10446810  1
1999 Grubber JM, Saunders AM, Crane-Gatherum AR, Scott WK, Martin ER, Haynes CS, Conneally PM, Small GW, Roses AD, Haines JL, Pericak-Vance MA. Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K). Neuroscience Letters. 269: 115-9. PMID 10430518 DOI: 10.1016/S0304-3940(99)00426-7  1
1999 Small GW, Chen ST, Komo S, Ercoli L, Bookheimer S, Miller K, Lavretsky H, Saxena S, Kaplan A, Dorsey D, Scott WK, Saunders AM, Haines JL, Roses AD, Pericak-Vance MA. Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele. The American Journal of Psychiatry. 156: 1035-8. PMID 10401448  1
1999 Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, Song Y, Hill DL, Abou-Donia SM, Martin ER, Vance JJ, Yu G, Orlacchio A, Pei Y, Nishimura M, ... ... Roses AD, et al. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nature Genetics. 22: 19-22. PMID 10319855 DOI: 10.1038/8729  1
1999 Horsburgh K, Kelly S, McCulloch J, Higgins GA, Roses AD, Nicoll JA. Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia. Neuroreport. 10: 837-41. PMID 10208557  1
1999 Xu PT, Schmechel D, Qiu HL, Herbstreith M, Rothrock-Christian T, Eyster M, Roses AD, Gilbert JR. Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice. Neurobiology of Disease. 6: 63-75. PMID 10078974 DOI: 10.1006/nbdi.1998.0213  1
1999 Scott WK, Grubber JM, Abou-Donia SM, Church TD, Saunders AM, Roses AD, Pericak-Vance MA, Conneally PM, Small GW, Haines JL. Further evidence linking late-onset Alzheimer disease with chromosome 12. Jama. 281: 513-4. PMID 10022104 DOI: 10.1001/jama.281.6.513  1
1998 Scott WK, Yamaoka LH, Bass MP, Gaskell PC, Conneally PM, Small GW, Farrer LA, Auerbach SA, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics. 1: 179-83. PMID 10737120  1
1998 Gilbert JR, Guy V, Kumar A, Wolpert C, Kandt R, Aylesworth A, Roses AD, Pericak-Vance MA. Mutation and polymorphism analysis in the tuberous sclerosis 2 (TSC2) gene. Neurogenetics. 1: 267-72. PMID 10732801  1
1998 Roses AD. Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg. Annals of the New York Academy of Sciences. 855: 738-43. PMID 9929679  1
1998 Roses AD. Genetic testing and Alzheimer disease: the promise. Alzheimer Disease and Associated Disorders. 12: S3-9. PMID 9876936  1
1998 Einstein G, Patel V, Bautista P, Kenna M, Melone L, Fader R, Karson K, Mann S, Saunders AM, Hulette C, Mash D, Roses AD, Schmechel DE. Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology. Journal of Neuropathology and Experimental Neurology. 57: 1190-201. PMID 9862642  1
1998 Williams KR, Saunders AM, Roses AD, Armati PJ. Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons. Neurobiology of Disease. 5: 271-9. PMID 9848097 DOI: 10.1006/nbdi.1998.0198  1
1998 Farrer LA, Abraham CR, Haines JL, Rogaeva EA, Song Y, McGraw WT, Brindle N, Premkumar S, Scott WK, Yamaoka LH, Saunders AM, Roses AD, Auerbach SA, Sorbi S, Duara R, et al. Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Annals of Neurology. 44: 808-11. PMID 9818937 DOI: 10.1002/ana.410440515  1
1998 Roses AD. Patent income. Science (New York, N.Y.). 281: 1805. PMID 9776680  1
1998 Bass MP, Yamaoka LH, Scott WK, Gaskell PC, Welsh-Bohmer KA, Roses AD, Saunders AM, Haines JL, Pericak-Vance MA. No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients. Neuroscience Letters. 250: 79-82. PMID 9697923 DOI: 10.1016/S0304-3940(98)00398-X  1
1998 Mihovilovic M, Mai Y, Austin C, Roses AD. Sera from myasthenia gravis patients recognize the PEVK domain of titin. Annals of the New York Academy of Sciences. 841: 534-7. PMID 9668289 DOI: 10.1111/j.1749-6632.1998.tb10977.x  1
1998 Mihovilovic M, Denning S, Mai Y, Fisher CM, Whichard LP, Patel DD, Roses AD. Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes. Annals of the New York Academy of Sciences. 841: 388-92. PMID 9668263 DOI: 10.1111/j.1749-6632.1998.tb10951.x  1
1998 Thomas AM, Cohen G, Cook-Deegan RM, O'Sullivan J, Post SG, Roses AD, Schaffner KF, Green RM. Alzheimer testing at Silver Years. Cambridge Quarterly of Healthcare Ethics : Cq : the International Journal of Healthcare Ethics Committees. 7: 294-307. PMID 9663350  1
1998 Xu PT, Gilbert JR, Qiu HL, Rothrock-Christian T, Settles DL, Roses AD, Schmechel DE. Regionally specific neuronal expression of human APOE gene in transgenic mice. Neuroscience Letters. 246: 65-8. PMID 9627181 DOI: 10.1016/S0304-3940(98)00247-X  1
1998 Scott BL, Welch K, deSerrano V, Moss NC, Roses AD, Strittmatter WJ. Human apolipoprotein E accelerates microtubule polymerization in vitro. Neuroscience Letters. 245: 105-8. PMID 9605496 DOI: 10.1016/S0304-3940(98)00180-3  1
1998 Tamaoka A, Fraser PE, Ishii K, Sahara N, Ozawa K, Ikeda M, Saunders AM, Komatsuzaki Y, Sherrington R, Levesque G, Yu G, Rogaeva E, Shoji S, Nee LE, Pollen DA, ... ... Roses AD, et al. Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. Brain Research. Molecular Brain Research. 56: 178-85. PMID 9602117 DOI: 10.1016/S0169-328X(98)00044-8  1
1998 Laskowitz DT, Horsburgh K, Roses AD. Apolipoprotein E and the CNS response to injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 465-71. PMID 9591838 DOI: 10.1097/00004647-199805000-00001  1
1998 Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Christian-Rothrock T, Saunders AM, Maeda N, Schmechel DE. Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiology of Aging. 19: S53-8. PMID 9562469 DOI: 10.1016/S0197-4580(98)00030-X  1
1998 Pericak-Vance MA, Bass ML, Yamaoka LH, Gaskell PC, Scott WK, Terwedow HA, Menold MM, Conneally PM, Small GW, Saunders AM, Roses AD, Haines JL. Complete genomic screen in late-onset familial Alzheimer's disease. Neurobiology of Aging. 19: S39-42. PMID 9562466 DOI: 10.1016/S0197-4580(98)00037-2  1
1998 Davies P, Resnick J, Resnick B, Gilman S, Growdon JH, Khachaturian ZS, Radebaugh TS, Roses AD, Selkoe DJ, Trojanowski JQ, Blass JP, Gibson GE, Sheu KFR, Blennow K, Delacourte A, et al. Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' Neurobiology of Aging. 19: 109-116. PMID 9558143 DOI: 10.1016/S0197-4580(98)00022-0  1
1998 Roses AD. Genetic associations. Lancet. 351: 916. PMID 9525410 DOI: 10.1016/S0140-6736(05)70341-X  1
1998 Roses AD. Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases. American Journal of Medical Genetics. 81: 49-57. PMID 9514588 DOI: 10.1002/(SICI)1096-8628(19980207)81:1<49::AID-AJMG10>3.0.CO;2-W  1
1998 Guyton JR, Miller SE, Martin ME, Khan WA, Roses AD, Strittmatter WJ. Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid. Journal of Neurochemistry. 70: 1235-40. PMID 9489746  1
1998 Robertson TA, Dutton NS, Martins RN, Roses AD, Kakulas BA, Papadimitriou JM. Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice. Neuroscience. 82: 171-80. PMID 9483513 DOI: 10.1016/S0306-4522(97)00284-4  1
1998 Mayeux R, Saunders AM, Shea S, Mirra S, Evans D, Roses AD, Hyman BT, Crain B, Tang MX, Phelps CH. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease. The New England Journal of Medicine. 338: 506-11. PMID 9468467 DOI: 10.1056/NEJM199802193380804  1
1998 Cooper AJL, Sheu KFR, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly- Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions? Age. 21: 25-30.  1
1998 Laskowitz DT, Roses AD. Apolipoprotein E: An expanding role in the neurobiology of disease Alzheimer's Reports. 1: 5-12.  1
1997 Roses AD. A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease. Neurogenetics. 1: 3-11. PMID 10735268  1
1997 Speer MC, Pericak-Vance MA, Stajich JM, Sarrica J, Jordan M, Roses AD, Vance JM, Gilbert JR. Further exclusion of FSHD1B from the telomeric region of 10q. Neurogenetics. 1: 151-2. PMID 10732819  1
1997 Scott WK, Staijich JM, Yamaoka LH, Speer MC, Vance JM, Roses AD, Pericak-Vance MA. Genetic complexity and Parkinson's disease. Deane Laboratory Parkinson Disease Research Group. Science (New York, N.Y.). 277: 387-8; author reply . PMID 9518366 DOI: 10.1126/science.277.5324.387  1
1997 Roses AD, Saunders AM. Apolipoprotein E genotyping as a diagnostic adjunct for Alzheimer's disease. International Psychogeriatrics / Ipa. 9: 277-88; discussion 3. PMID 9447448  1
1997 Okochi M, Ishii K, Usami M, Sahara N, Kametani F, Tanaka K, Fraser PE, Ikeda M, Saunders AM, Hendriks L, Shoji SI, Nee LE, Martin JJ, Van Broeckhoven C, St George-Hyslop PH, ... Roses AD, et al. Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations. Febs Letters. 418: 162-6. PMID 9414118 DOI: 10.1016/S0014-5793(97)01378-1  1
1997 Mihovilovic M, Denning S, Mai Y, Whichard LP, Patel DD, Roses AD. Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5 and beta-4 subunits of neuronal nicotinic acetylcholine receptors: preferential transcription of the alpha-3 and beta-4 genes by immature CD4 + 8 + thymocytes. Journal of Neuroimmunology. 79: 176-84. PMID 9394790 DOI: 10.1016/S0165-5728(97)00120-3  1
1997 Stajich JM, Gilchrist JM, Lennon F, Lee A, Yamaoka L, Rosi B, Gaskell PC, Pritchard M, Donald L, Roses AD, Vance JM, Pericak-Vance MA. Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13 in American families suggests the existence of a second causal mutation. Neuromuscular Disorders : Nmd. 7: S75-81. PMID 9392021 DOI: 10.1016/S0960-8966(97)00087-4  1
1997 Roses AD. Apolipoprotein E, a gene with complex biological interactions in the aging brain. Neurobiology of Disease. 4: 170-85. PMID 9361294 DOI: 10.1006/nbdi.1997.0161  1
1997 Cooper AJ, Sheu KR, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. Proceedings of the National Academy of Sciences of the United States of America. 94: 12604-9. PMID 9356496 DOI: 10.1073/pnas.94.23.12604  1
1997 Roses AD. Genetic testing for Alzheimer disease. Practical and ethical issues. Archives of Neurology. 54: 1226-9. PMID 9341568  1
1997 Pericak-Vance MA, Bass MP, Yamaoka LH, Gaskell PC, Scott WK, Terwedow HA, Menold MM, Conneally PM, Small GW, Vance JM, Saunders AM, Roses AD, Haines JL. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. Jama. 278: 1237-41. PMID 9333264  1
1997 Roses AD, Saunders AM. ApoE, Alzheimer's disease, and recovery from brain stress. Annals of the New York Academy of Sciences. 826: 200-12. PMID 9329691 DOI: 10.1111/j.1749-6632.1997.tb48471.x  1
1997 Tardiff BE, Newman MF, Saunders AM, Strittmatter WJ, Blumenthal JA, White WD, Croughwell ND, Davis RD, Roses AD, Reves JG. Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center. The Annals of Thoracic Surgery. 64: 715-20. PMID 9307463 DOI: 10.1016/S0003-4975(97)00757-1  1
1997 Scott WK, Saunders AM, Gaskell PC, Locke PA, Growdon JH, Farrer LA, Auerbach SA, Roses AD, Haines JL, Pericak-Vance MA. Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. Annals of Neurology. 42: 376-8. PMID 9307262 DOI: 10.1002/ana.410420317  1
1997 Welsh-Bohmer KA, Gearing M, Saunders AM, Roses AD, Mirra S. Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Annals of Neurology. 42: 319-25. PMID 9307253 DOI: 10.1002/ana.410420308  1
1997 Onodera O, Burke JR, Miller SE, Hester S, Tsuji S, Roses AD, Strittmatter WJ. Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells. Biochemical and Biophysical Research Communications. 238: 599-605. PMID 9299559 DOI: 10.1006/bbrc.1997.7337  1
1997 Mitsuda N, Roses AD, Vitek MP. Transcriptional regulation of the mouse presenilin-1 gene. The Journal of Biological Chemistry. 272: 23489-97. PMID 9295283 DOI: 10.1074/jbc.272.38.23489  1
1997 Laskowitz DT, Sheng H, Bart RD, Joyner KA, Roses AD, Warner DS. Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 753-8. PMID 9270492 DOI: 10.1097/00004647-199707000-00005  1
1997 Williams KR, Pye V, Saunders AM, Roses AD, Armati PJ. Apolipoprotein E uptake and low-density lipoprotein receptor-related protein expression by the NTera2/D1 cell line: a cell culture model of relevance for late-onset Alzheimer's disease. Neurobiology of Disease. 4: 58-67. PMID 9258912 DOI: 10.1006/nbdi.1997.0131  1
1997 Roses AD. Alzheimer's disease: the genetics of risk. Hospital Practice (1995). 32: 51-5, 58-63, 67-9. PMID 9227658  1
1997 Alexander GE, Saunders AM, Szczepanik J, Strassburger TL, Pietrini P, Dani A, Furey ML, Mentis MJ, Roses AD, Rapoport SI, Schapiro MB. Relation of age and apolipoprotein E to cognitive function in Down syndrome adults. Neuroreport. 8: 1835-40. PMID 9223061  1
1997 Roses AD, Saunders AM. Clinical overdiagnosis of vascular dementia versus necropsy confirmed series. Journal of Neurology, Neurosurgery, and Psychiatry. 62: 677-8. PMID 9219771  1
1997 Cooper AJ, Sheu KF, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases? Journal of Neurochemistry. 69: 431-4. PMID 9202340  1
1997 Hulette CM, Welsh-Bohmer KA, Crain B, Szymanski MH, Sinclaire NO, Roses AD. Rapid brain autopsy. The Joseph and Kathleen Bryan Alzheimer's Disease Research Center experience. Archives of Pathology & Laboratory Medicine. 121: 615-8. PMID 9199629  1
1997 Roses AD. Mutational and susceptibility genetics are different clinical paradigms. International Psychogeriatrics / Ipa. 9: 7-10. PMID 9195274 DOI: 10.1017/S1041610297004158  1
1997 Scott WK, Yamaoka LH, Locke PA, Rosi BL, Gaskell PC, Saunders AM, Conneally PM, Small GW, Farrer LA, Growdon JH, Roses AD, Pericak-Vance MA, Haines JL. No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genetic Epidemiology. 14: 307-15. PMID 9181359 DOI: 10.1002/(SICI)1098-2272(1997)14:3<307::AID-GEPI8>3.0.CO;2-1  1
1997 Alberts MJ, Davis JP, Graffagnino C, McClenny C, Delong D, Granger C, Herbstreith MH, Boteva K, Marchuk DA, Roses AD. Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. Annals of Neurology. 41: 683-6. PMID 9153532 DOI: 10.1002/ana.410410519  1
1997 Small GW, Noble EP, Matsuyama SS, Jarvik LF, Komo S, Kaplan A, Ritchie T, Pritchard ML, Saunders AM, Conneally PM, Roses AD, Haines JL, Pericak-Vance MA. D2 dopamine receptor A1 allele in Alzheimer disease and aging. Archives of Neurology. 54: 281-5. PMID 9074397  1
1997 Roses AD, Saunders AM. Prediction for unimpaired subjects is different from diagnosis of demented patients. Annals of Neurology. 41: 414-6. PMID 9066367 DOI: 10.1002/ana.410410322  1
1997 Post SG, Whitehouse PJ, Binstock RH, Bird TD, Eckert SK, Farrer LA, Fleck LM, Gaines AD, Juengst ET, Karlinsky H, Miles S, Murray TH, Quaid KA, Relkin NR, Roses AD, et al. The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective. Jama. 277: 832-6. PMID 9052715  1
1997 Lippa CF, Smith TW, Saunders AM, Hulette C, Pulaski-Salo D, Roses AD. Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype. Neurology. 48: 515-9. PMID 9040748  1
1997 Robertson TA, Dutton NS, Martins RN, Roses AD, Kakulas BA, Papadimitriou JM. Beta-amyloid protein-containing inclusions in skeletal muscle of apolipoprotein-E-deficient mice. The American Journal of Pathology. 150: 417-27. PMID 9033257  1
1997 Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Rothrook TC, Saunders AM, Maeda N, Schmechel DF. APOE and Alzheimer disease: Human susceptibility genes and appropriate transgenic models Brain Pathology. 7: 1033-1036.  1
1997 Roses AD. Apolipoprotein e and alzheimer's disease: The tip of the susceptibility iceberg Faseb Journal. 11: A1004.  1
1996 Strittmatter WJ, Burke JR, DeSerrano VS, Huang DY, Matthew W, Saunders AM, Scott BL, Vance JM, Weisgraber KH, Roses AD. Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases. Cold Spring Harbor Symposia On Quantitative Biology. 61: 597-605. PMID 9246486  1
1996 Small GW, Komo S, La Rue A, Saxena S, Phelps ME, Mazziotta JC, Saunders AM, Haines JL, Pericak-Vance MA, Roses AD. Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging. Annals of the New York Academy of Sciences. 802: 70-8. PMID 8993486 DOI: 10.1111/j.1749-6632.1996.tb32600.x  1
1996 Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, et al. No association between alpha 1-antichymotrypsin and familial Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 35-41. PMID 8993482 DOI: 10.1111/j.1749-6632.1996.tb32596.x  1
1996 Onodera O, Roses AD, Tsuji S, Vance JM, Strittmatter WJ, Burke JR. Toxicity of expanded polyglutamine-domain proteins in Escherichia coli. Febs Letters. 399: 135-9. PMID 8980137 DOI: 10.1016/S0014-5793(96)01301-4  1
1996 Xu PT, Schmechel D, Rothrock-Christian T, Burkhart DS, Qiu HL, Popko B, Sullivan P, Maeda N, Saunders AM, Roses AD, Gilbert JR. Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiology of Disease. 3: 229-45. PMID 8980023 DOI: 10.1006/nbdi.1996.0023  1
1996 Roses AD, Saunders AM. Evaluation of suspected dementia. The New England Journal of Medicine. 335: 1996; author reply 1. PMID 8975127 DOI: 10.1056/NEJM199612263352613  1
1996 Roses AD, Bryan J, Bryan K. Apolipoprotein E genotype: utility in clinical practice in Alzheimer's disease. Journal of the American Geriatrics Society. 44: 1479-81. PMID 8951322 DOI: 10.1111/j.1532-5415.1996.tb04077.x  1
1996 Yamaoka LH, Welsh-Bohmer KA, Hulette CM, Gaskell PC, Murray M, Rimmler JL, Helms BR, Guerra M, Roses AD, Schmechel DE, Pericak-Vance MA. Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype. American Journal of Human Genetics. 59: 1306-12. PMID 8940276  1
1996 Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer's disease. Annual Review of Neuroscience. 19: 53-77. PMID 8833436 DOI: 10.1146/annurev.ne.19.030196.000413  1
1996 Meckelein B, de Silva HA, Roses AD, Rao PN, Pettenati MJ, Xu PT, Hodge R, Glucksman MJ, Abraham CR. Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset alzheimer disease AD2 locus. Genomics. 31: 246-9. PMID 8824811 DOI: 10.1006/geno.1996.0041  1
1996 Askanas V, Engel WK, Mirabella M, Weisgraber KH, Saunders AM, Roses AD, McFerrin J. Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy. Annals of Neurology. 40: 264-5. PMID 8773613 DOI: 10.1002/ana.410400223  1
1996 Xia Y, Rohan de Silva HA, Rosi BL, Yamaoka LH, Rimmler JB, Pericak-Vance MA, Roses AD, Chen X, Masliah E, DeTeresa R, Iwai A, Sundsmo M, Thomas RG, Hofstetter CR, Gregory E, et al. Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism. Annals of Neurology. 40: 207-15. PMID 8773602 DOI: 10.1002/ana.410400212  1
1996 Pritchard ML, Saunders AM, Gaskell PC, Small GW, Conneally PM, Rosi B, Yamaoka LH, Roses AD, Haines JL, Pericak-Vance MA. No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians. Neuroscience Letters. 209: 105-8. PMID 8761993 DOI: 10.1016/0304-3940(96)12630-6  1
1996 Roses AD, Einstein G, Gilbert J, Goedert M, Han SH, Huang D, Hulette C, Masliah E, Pericak-Vance MA, Saunders AM, Schmechel DE, Strittmatter WJ, Weisgraber KH, Xi PT. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Annals of the New York Academy of Sciences. 777: 146-57. PMID 8624078  1
1996 Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, et al. No genetic effect of alpha1-antichymotrypsin in Alzheimer disease. Genomics. 33: 53-6. PMID 8617509 DOI: 10.1006/geno.1996.0158  1
1996 Lippa CF, Saunders AM, Smith TW, Swearer JM, Drachman DA, Ghetti B, Nee L, Pulaski-Salo D, Dickson D, Robitaille Y, Bergeron C, Crain B, Benson MD, Farlow M, Hyman BT, ... ... Roses AD, et al. Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology. 46: 406-12. PMID 8614503  1
1996 Burke JR, Enghild JJ, Martin ME, Jou YS, Myers RM, Roses AD, Vance JM, Strittmatter WJ. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nature Medicine. 2: 347-50. PMID 8612237  1
1996 Scott WK, Growdon JH, Roses AD, Haines JL, Pericak-Vance MA. Presenilin-1 polymorphism and Alzheimer's disease. Lancet (London, England). 347: 1186-7. PMID 8609784  1
1995 Breitner JC, Welsh KA, Helms MJ, Gaskell PC, Gau BA, Roses AD, Pericak-Vance MA, Saunders AM. Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs. Neurobiology of Aging. 16: 523-30. PMID 8544901 DOI: 10.1016/0197-4580(95)00049-K  1
1995 Othmane KB, Loeb D, Hayworth-Hodgte R, Hentati F, Rao N, Roses AD, Ben Hamida M, Pericak-Vance MA, Vance JM. Physical and genetic mapping of the CMT4A locus and exclusion of PMP-2 as the defect in CMT4A. Genomics. 28: 286-90. PMID 8530038 DOI: 10.1006/geno.1995.1143  1
1995 Roses AD, Saunders AM, Alberts MA, Strittmatter WJ, Schmechel D, Gorder E, Pericak-Vance MA. Apolipoprotein E E4 allele and risk of dementia. Jama. 273: 374-5; author reply . PMID 7823377 DOI: 10.1001/jama.1995.03520290026015  1
1995 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Roses AD, Pericak-Vance MA, Small GW, Haines JL. The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. Jama. 273: 373-4. PMID 7823376 DOI: 10.1001/jama.1995.03520290025013  1
1995 Roses AD, Saunders AM, Strittmatter WJ, Schmechel DE, Pericak-Vance MA, Hyman B. Apolipoprotein E in Creutzfeldt-Jacob disease. Lancet. 345: 69. PMID 7799733  1
1995 Roses AD, Saunders AM, Corder EH, Pericak-Vance MA, Han SH, Einstein G, Hulette C, Schmechel DE, Holsti M, Huang D. Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease. Arzneimittel-Forschung. 45: 413-7. PMID 7763336  1
1995 Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 92: 4725-7. PMID 7761390 DOI: 10.1073/pnas.92.11.4725  1
1995 Mounsey JP, Xu P, John JE, Horne LT, Gilbert J, Roses AD, Moorman JR. Modulation of skeletal muscle sodium channels by human myotonin protein kinase. The Journal of Clinical Investigation. 95: 2379-84. PMID 7738201 DOI: 10.1172/JCI117931  1
1995 Ben Othmane K, Speer MC, Stauffer J, Blel S, Middleton L, Ben Hamida C, Etribi A, Loeb D, Hentati F, Roses AD. Evidence for linkage disequilibrium in chromosome 13-linked Duchenne-like muscular dystrophy (LGMD2C) American Journal of Human Genetics. 57: 732-4. PMID 7668303  1
1995 Alberts MJ, Graffagnino C, McClenny C, DeLong D, Strittmatter W, Saunders AM, Roses AD. ApoE genotype and survival from intracerebral haemorrhage. Lancet. 346: 575. PMID 7658797 DOI: 10.1016/S0140-6736(95)91411-0  1
1995 Chen X, de Silva HA, Pettenati MJ, Rao PN, St George-Hyslop P, Roses AD, Xia Y, Horsburgh K, Uéda K, Saitoh T. The human NACP/alpha-synuclein gene: chromosome assignment to 4q21.3-q22 and TaqI RFLP analysis. Genomics. 26: 425-7. PMID 7601479 DOI: 10.1016/0888-7543(95)80237-G  1
1995 Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, ... ... Roses AD, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375: 754-60. PMID 7596406 DOI: 10.1038/375754a0  1
1995 Huang DY, Weisgraber KH, Goedert M, Saunders AM, Roses AD, Strittmatter WJ. ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neuroscience Letters. 192: 209-12. PMID 7566652 DOI: 10.1016/0304-3940(95)11649-H  1
1995 Masliah E, Mallory M, Ge N, Alford M, Veinbergs I, Roses AD. Neurodegeneration in the central nervous system of apoE-deficient mice. Experimental Neurology. 136: 107-22. PMID 7498401 DOI: 10.1006/exnr.1995.1088  1
1995 Graffagnino C, Herbstreith MH, Schmechel DE, Levy E, Roses AD, Alberts MJ. Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage. Stroke; a Journal of Cerebral Circulation. 26: 2190-3. PMID 7482672  1
1994 Roses AD, Pericak-Vance MA, Saunders AM, Schmechel D, Goldgaber D, Strittmatter W. Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy? Epilepsia. 35: S20-8. PMID 8293721  1
1994 Roses AD. Muscle biochemistry and a genetic study of myotonic dystrophy. Science (New York, N.Y.). 264: 587-8. PMID 8160018  1
1994 Peacock ML, Murman DL, Sima AA, Warren JT, Roses AD, Fink JK. Novel amyloid precursor protein gene mutation (codon 665Asp) in a patient with late-onset Alzheimer's disease. Annals of Neurology. 35: 432-8. PMID 8154870 DOI: 10.1002/ana.410350410  1
1994 Samson F, Mesnard L, Mihovilovic M, Potter TG, Mercadier JJ, Roses AD, Gilbert JR. A new human slow skeletal troponin T (TnTs) mRNA isoform derived from alternative splicing of a single gene. Biochemical and Biophysical Research Communications. 199: 841-7. PMID 8135831 DOI: 10.1006/bbrc.1994.1305  1
1994 Han SH, Einstein G, Weisgraber KH, Strittmatter WJ, Saunders AM, Pericak-Vance M, Roses AD, Schmechel DE. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. Journal of Neuropathology and Experimental Neurology. 53: 535-44. PMID 8083695  1
1994 Näslund J, Schierhorn A, Hellman U, Lannfelt L, Roses AD, Tjernberg LO, Silberring J, Gandy SE, Winblad B, Greengard P. Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging. Proceedings of the National Academy of Sciences of the United States of America. 91: 8378-82. PMID 8078890  1
1994 Han SH, Hulette C, Saunders AM, Einstein G, Pericak-Vance M, Strittmatter WJ, Roses AD, Schmechel DE. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Experimental Neurology. 128: 13-26. PMID 8070517 DOI: 10.1006/exnr.1994.1108  1
1994 Weisgraber KH, Roses AD, Strittmatter WJ. The role of apolipoprotein E in the nervous system. Current Opinion in Lipidology. 5: 110-6. PMID 8044413  1
1994 Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. The Journal of Clinical Investigation. 94: 860-9. PMID 8040342 DOI: 10.1172/JCI117407  1
1994 Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, Huang DY, Pericak-Vance M, Schmechel D, Roses AD. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 11183-6. PMID 7972031  1
1994 Goedert M, Strittmatter WJ, Roses AD. Alzheimer's disease. Risky apolipoprotein in brain. Nature. 372: 45-6. PMID 7969418 DOI: 10.1038/372045a0  1
1994 Burke JR, Wingfield MS, Lewis KE, Roses AD, Lee JE, Hulette C, Pericak-Vance MA, Vance JM. The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family. Nature Genetics. 7: 521-4. PMID 7951323 DOI: 10.1038/ng0894-521  1
1994 Fink JK, Peacock ML, Warren JT, Roses AD, Prusiner SB. Detecting prion protein gene mutations by denaturing gradient gel electrophoresis. Human Mutation. 4: 42-50. PMID 7951257 DOI: 10.1002/humu.1380040106  1
1994 Graffagnino C, Herbstreith MH, Roses AD, Alberts MJ. A molecular genetic study of intracerebral hemorrhage. Archives of Neurology. 51: 981-4. PMID 7945009  0.56
1994 Huang DY, Goedert M, Jakes R, Weisgraber KH, Garner CC, Saunders AM, Pericak-Vance MA, Schmechel DE, Roses AD, Strittmatter WJ. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neuroscience Letters. 182: 55-8. PMID 7891887 DOI: 10.1016/0304-3940(94)90204-6  1
1994 Yamaoka LH, Westbrook CA, Speer MC, Gilchrist JM, Jabs EW, Schweins EG, Stajich JM, Gaskell PC, Roses AD, Pericak-Vance MA. Development of a microsatellite genetic map spanning 5q31-q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9. Neuromuscular Disorders : Nmd. 4: 471-5. PMID 7881291 DOI: 10.1016/0960-8966(94)90086-8  1
1993 Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 1977-81. PMID 8446617  1
1993 Schmechel DE, Saunders AM, Strittmatter WJ, Crain BJ, Hulette CM, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 9649-53. PMID 8415756  1
1993 Strittmatter WJ, Huang DY, Bhasin R, Roses AD, Goldgaber D. Avid binding of beta A amyloid peptide to its own precursor. Experimental Neurology. 122: 327-34. PMID 8405269 DOI: 10.1006/exnr.1993.1132  1
1993 Phillips KL, Gartrell DM, Roses AD, Lee JE. A triplet repeat polymorphism in a gene expressed in human hypothalamus. Human Molecular Genetics. 2: 1332. PMID 8401526 DOI: 10.1093/hmg/2.8.1332-a  1
1993 Strittmatter WJ, Weisgraber KH, Huang DY, Dong LM, Salvesen GS, Pericak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 8098-102. PMID 8367470  1
1993 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science (New York, N.Y.). 261: 921-3. PMID 8346443  1
1993 Pericak-Vance MA, St George-Hyslop PH, Gaskell PC, Growdon J, Crain BJ, Hulette C, Gusella JF, Yamaoka L, Tanzi RE, Roses AD. Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets. Genetic Epidemiology. 10: 361-4. PMID 8314027 DOI: 10.1002/gepi.1370100605  1
1993 Ben Othmane K, Hentati F, Lennon F, Ben Hamida C, Blel S, Roses AD, Pericak-Vance MA, Ben Hamida M, Vance JM. Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q. Human Molecular Genetics. 2: 1625-8. PMID 8268915  1
1993 Goldgaber D, Schwarzman AI, Bhasin R, Gregori L, Schmechel D, Saunders AM, Roses AD, Strittmatter WJ. Sequestration of amyloid beta-peptide. Annals of the New York Academy of Sciences. 695: 139-43. PMID 8239272 DOI: 10.1111/j.1749-6632.1993.tb23042.x  1
1993 Huang D, Martin M, Hu D, Roses AD, Goldgaber D, Strittmatter WJ. Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding. Journal of Neuroimmunology. 48: 199-203. PMID 8227317 DOI: 10.1016/0165-5728(93)90192-2  1
1993 Peacock ML, Warren JT, Roses AD, Fink JK. Novel polymorphism in the A4 region of the amyloid precursor protein gene in a patient without Alzheimer's disease. Neurology. 43: 1254-6. PMID 8170579  1
1993 Haas M, Ward DC, Lee J, Roses AD, Clarke V, D'Eustachio P, Lau D, Vega-Saenz de Miera E, Rudy B. Localization of Shaw-related K+ channel genes on mouse and human chromosomes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 711-5. PMID 8111118 DOI: 10.1007/BF00357794  1
1993 Zeldenrust SR, Murrell J, Farlow M, Ghetti B, Roses AD, Benson MD. RFLP analysis for APP 717 mutations associated with Alzheimer's disease. Journal of Medical Genetics. 30: 476-8. PMID 7686976  1
1992 Gilbert JR, Stajich JM, Speer MC, Vance JM, Stewart CS, Yamaoka LH, Samson F, Fardeau M, Potter TG, Roses AD. Linkage studies in facioscapulohumeral muscular dystrophy (FSHD). American Journal of Human Genetics. 51: 424-7. PMID 1642241  1
1992 Sharp NJ, Kornegay JN, Van Camp SD, Herbstreith MH, Secore SL, Kettle S, Hung WY, Constantinou CD, Dykstra MJ, Roses AD. An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy. Genomics. 13: 115-21. PMID 1577476  0.56
1992 Constantinou-Deltas CD, Gilbert J, Bartlett RJ, Herbstreith M, Roses AD, Lee JE. The identification and characterization of KRAB-domain-containing zinc finger proteins. Genomics. 12: 581-9. PMID 1559709  0.44
1992 Loprest LJ, Pericak-Vance MA, Stajich J, Gaskell PC, Lucas AM, Lennon F, Yamaoka LH, Roses AD, Vance JM. Linkage studies in Charcot-Marie-Tooth disease type 2: evidence that CMT types 1 and 2 are distinct genetic entities. Neurology. 42: 597-601. PMID 1549221  1
1992 Samson F, de Jong PJ, Trask BJ, Koza-Taylor P, Speer MC, Potter T, Roses AD, Gilbert JR. Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis. Genomics. 13: 1374-5. PMID 1505979 DOI: 10.1016/0888-7543(92)90077-6  1
1992 Kazantsev A, Yamaoka LH, Roses AD. A dinucleotide repeat polymorphism in the human Na+,K+ ATPase, alpha subunit (ATP1A3) gene. Nucleic Acids Research. 20: 1164. PMID 1312709  0.44
1992 Phillips KL, Garbutt JH, Roses AD, Lee JE. A chromosome 19 CA-dinucleotide repeat polymorphism. Human Molecular Genetics. 1: 551. PMID 1307260 DOI: 10.1093/hmg/1.7.551-a  1
1992 Ben Othmane K, Ben Hamida M, Pericak-Vance MA, Ben Hamida C, Blel S, Carter SC, Bowcock AM, Petruhkin K, Gilliam TC, Roses AD. Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q. Nature Genetics. 2: 315-7. PMID 1303286 DOI: 10.1038/ng1292-315  1
1991 Roses AD, Conneally PM. Alzheimer's disease cell bank. Science (New York, N.Y.). 252: 14. PMID 2011751  1
1991 Goodkin DE, Doolittle TH, Hauser SS, Ransohoff RM, Roses AD, Rudick RA. Diagnostic criteria for multiple sclerosis research involving multiply affected families. Archives of Neurology. 48: 805-7. PMID 1898254 DOI: 10.1001/archneur.1991.00530200041016  1
1991 Alberts MJ, Kandt RS, Pericak-Vance MA, Bebout J, Speer MC, Siddique TS, Yamaoka L, Hung WY, Gaskell PC, Roses AD. MspI RFLP for microtubule associated protein-2 (MAP2). Nucleic Acids Research. 19: 960. PMID 1708129 DOI: 10.1093/nar/19.4.960  1
1991 Samson F, Gilbert JR, Koza-Taylor P, Speer MC, Lee J, Roses AD. A PstI polymorphism detected by a genomic clone at the human slow troponin T (TNNT1) gene locus. Nucleic Acids Research. 19: 6058. PMID 1682896 DOI: 10.1093/nar/19.21.6058  1
1991 Lucas AM, Vance JM, Stajich JM, Roses AD. A PvuII polymorphism detected by pEW404 (D17S64) on chromosome 17. Nucleic Acids Research. 19: 5802. PMID 1682890 DOI: 10.1093/nar/19.20.5802-a  1
1991 Alberts MJ, Pericak-Vance MA, Royal V, Bebout J, Gaskell P, Thomas J, Hung WY, Clark C, Earl N, Roses AD. Genetic linkage analysis of nerve growth factor (beta) in familial Alzheimer's disease. Annals of Neurology. 30: 216-9. PMID 1680304 DOI: 10.1002/ana.410300217  0.44
1991 Royal V, Alberts MJ, Pericak-Vance MA, Finocchiaro G, Bebout J, Yamaoka L, Hung WY, Gaskell PC, Roses AD. RsaI RFLP for electron transport flavoprotein-beta(ETFB). Nucleic Acids Research. 19: 4021. PMID 1677763  0.44
1991 Vance JM, Barker D, Yamaoka LH, Stajich JM, Loprest L, Hung WY, Fischbeck K, Roses AD, Pericak-Vance MA. Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2. Genomics. 9: 623-8. PMID 1674726  0.44
1989 Laing NG, Siddique T, Bartlett R, Yamaoka LH, Hung WY, Pericak-Vance MA, Roses AD. Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry. Clinical Genetics. 35: 393-8. PMID 2736788  0.44
1989 Siddique T, Roper H, Pericak-Vance MA, Shaw J, Warner KL, Hung WY, Phillips KL, Lunt P, Cumming WJ, Roses AD. Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease. Journal of Medical Genetics. 26: 487-9. PMID 2570155 DOI: 10.1136/jmg.26.8.487  1
1989 Siddique T, Phillips K, Betz H, Grenningloh G, Warner K, Hung WY, Laing N, Roses AD. RFLPs of the gene for the human glycine receptor on the X-chromosome. Nucleic Acids Research. 17: 1785. PMID 2564191  0.44
1988 Siddique T, Bartlett R, Pericak-Vance M, Yamaoka L, Koh J, Chen J, Hung WY, Kandt R, Roses AD. Update on the molecular genetics of Duchenne muscular dystrophy. Australian Paediatric Journal. 24: 9-14. PMID 3060079  0.44
1988 Walker AP, Bartlett RJ, Laing NG, Siddique T, Yamaoka LH, Chen JC, Hung WY, Roses AD. RFLP for Duchenne muscular dystrophy cDNA clone 30-2. Nucleic Acids Research. 16: 9072. PMID 2902573  0.44
1988 Laing NG, Siddique T, Bartlett RJ, Yamaoka LH, Chen JC, Walker AP, Hung WY, Roses AD. RFLP for Duchenne muscular dystrophy cDNA clone 44-1. Nucleic Acids Research. 16: 7209. PMID 2900496  0.44
1988 Siddique T, McKinney R, Hung WY, Bartlett RJ, Bruns G, Mohandas TK, Ropers HH, Wilfert C, Roses AD. The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2. Genomics. 3: 156-60. PMID 2852161  0.44
1987 Vance JM, Pericak-Vance MA, Bowman MH, Payne CS, Fredane L, Siddique T, Roses AD, Massey EW. Chorea-acanthocytosis: a report of three new families and implications for genetic counselling. American Journal of Medical Genetics. 28: 403-10. PMID 3322006 DOI: 10.1002/ajmg.1320280219  0.44
1986 Roses AD, Pericak-Vance MA, Yamaoka LH, Herbstreith MH, Bartlett RJ, Siddique T, Hung WY, Ross DA, Mohandas TK, Bruns G. A new tightly linked DNA probe for myotonic dystrophy. Neurology. 36: 1146. PMID 3736889  0.56
1976 Roses AD, Roses MJ, Miller SE, Hull KL, Appel SH. Carrier detection in Duchenne muscular dystrophy. The New England Journal of Medicine. 294: 193-8. PMID 1244534 DOI: 10.1056/NEJM197601222940404  1
1976 Roses AD, Appel SH. Erythrocyte spectrin peak II phosphorylation in Duchenne muscular dystrophy. Journal of the Neurological Sciences. 29: 185-93. PMID 978207 DOI: 10.1016/0022-510X(76)90170-2  1
1976 Butterfield DA, Roses AD, Appel SH, Chesnut DB. Electron spin resonance studies of membrane proteins in erythrocytes in myotonic muscular dystrophy. Archives of Biochemistry and Biophysics. 177: 226-34. PMID 187121 DOI: 10.1016/0003-9861(76)90432-X  1
1976 Butterfield DA, Chesnut DB, Appel SH, Roses AD. Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia. Nature. 263: 159-61. PMID 184394 DOI: 10.1038/263159a0  1
1976 Roses AD, Herbstreith M, Metcalf B, Appel SH. Increased phosphorylated components of erythrocyte membrane spectrin band II with reference to Duchenne muscular dystrophy. Journal of the Neurological Sciences. 30: 167-78. PMID 10352  1
1976 Miller SE, Roses AD, Appel SH. Scanning electron microscopy studies in muscular dystrophy. Archives of Neurology. 33: 172-4. PMID 3154  1
1975 Miller SE, Roses AD, Appel SH. Letter: Erythrocytes in human muscular dystrophy. Science (New York, N.Y.). 188: 1131. PMID 1215993  1
1975 Roses AD, Herbstreith MH, Appel SH. Membrane protein kinase alteration in Duchenne muscular dystrophy. Nature. 254: 350-1. PMID 1118019  1
1975 Roses AD, Appel SH, Butterfield DA, Miller SE, Chesnut DB. Specificity of biochemical and biophysical tests in Duchenne and myotonic muscular dystrophy, carrier states, and congenital myotonia. Transactions of the American Neurological Association. 100: 131-4. PMID 179179  1
1975 Roses AD, Butterfield A, Appel SH, Chestnut DB. Phenytoin and membrane fluidity in myotonic dystrophy. Archives of Neurology. 32: 535-8. PMID 168843  1
1975 Roses AD, Appel SH. Phosphorylation of component a of the human erythrocyte membrane in myotonic muscular dystrophy. The Journal of Membrane Biology. 20: 51-8. PMID 123592 DOI: 10.1007/BF01870627  1
1974 Butterfield DA, Roses AD, Cooper ML, Appel SH, Chesnut DB. A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy. Biochemistry. 13: 5078-82. PMID 4373028  1
1974 Butterfield DA, Chesnut DB, Roses AD, Appel SH. Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 71: 909-13. PMID 4362637  1
1974 Roses AD, Appel SH. Muscle membrane protein kinase in myotonic muscular dystrophy. Nature. 250: 245-7. PMID 4277586 DOI: 10.1038/250245a0  1
1974 Roses AD, Appel SH. Letter: Muscular dystrophies. Lancet (London, England). 2: 1400. PMID 4143368  1
1973 Andrew CG, Roses AD, Almon RR, Appel SH. Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase. Science (New York, N.Y.). 182: 927-9. PMID 4355523  1
1973 Roses AD, Appel SH. Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 70: 1855-9. PMID 4352659  1
1973 Roses AD, Appel SH. Erythrocyte protein phosphorylation. The Journal of Biological Chemistry. 248: 1408-11. PMID 4346955  1
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