Ashley Harms - Publications

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Corbin-Stein NJ, Childers GM, Webster JM, Zane A, Yang YT, Mudium N, Gupta R, Manfredsson FP, Kordower JH, Harms AS. IFNγ drives neuroinflammation, demyelination, and neurodegeneration in a mouse model of multiple system atrophy. Acta Neuropathologica Communications. 12: 11. PMID 38238869 DOI: 10.1186/s40478-023-01710-x  0.464
2023 Chu Y, Hirst WD, Federoff HJ, Harms AS, Stoessl AJ, Kordower JH. Nigrostriatal tau pathology in parkinsonism and Parkinson's disease. Brain : a Journal of Neurology. PMID 38006313 DOI: 10.1093/brain/awad388  0.345
2023 Harms AS, Yang YT, Tansey MG. Central and peripheral innate and adaptive immunity in Parkinson's disease. Science Translational Medicine. 15: eadk3225. PMID 37939158 DOI: 10.1126/scitranslmed.adk3225  0.679
2023 Tansey MG, Harms AS. Editorial: Glial-targeted therapeutics for CNS disease: getting there from here. Frontiers in Cellular Neuroscience. 17: 1231648. PMID 37465212 DOI: 10.3389/fncel.2023.1231648  0.561
2023 Standaert DG, Harms AS, Childers GM, Webster JM. Disease mechanisms as subtypes: Inflammation in Parkinson disease and related disorders. Handbook of Clinical Neurology. 193: 95-106. PMID 36803825 DOI: 10.1016/B978-0-323-85555-6.00011-4  0.662
2022 Bloem BR, Brundin P, Harms A, Lindestam Arlehamn C, Tan EK, Williams-Gray CH. Linking Immune Activation and Parkinson's Disease. Journal of Parkinson's Disease. 12: S1-S3. PMID 36155531 DOI: 10.3233/JPD-229005  0.317
2022 Xu E, Boddu R, Abdelmotilib HA, Sokratian A, Kelly K, Liu Z, Bryant N, Chandra S, Carlisle SM, Lefkowitz EJ, Harms AS, Benveniste EN, Yacoubian TA, Volpicelli-Daley LA, Standaert DG, et al. Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain. Molecular Neurodegeneration. 17: 7. PMID 35012605 DOI: 10.1186/s13024-021-00509-5  0.82
2021 Chellappan R, Guha A, Si Y, Kwan T, Nabors LB, Filippova N, Yang X, Myneni AS, Meesala S, Harms AS, King PH. SRI-42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide-induced neuroinflammation. Glia. PMID 34533864 DOI: 10.1002/glia.24094  0.328
2021 Carlisle SM, Qin H, Hendrickson RC, Muwanguzi JE, Lefkowitz EJ, Kennedy RE, Yan Z, Yacoubian TA, Benveniste EN, West AB, Harms AS, Standaert DG. Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease. Npj Parkinson's Disease. 7: 36. PMID 33850148 DOI: 10.1038/s41531-021-00180-z  0.778
2021 Williams GP, Schonhoff AM, Jurkuvenaite A, Gallups NJ, Standaert DG, Harms AS. CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson disease. Brain : a Journal of Neurology. PMID 33704423 DOI: 10.1093/brain/awab103  0.807
2021 Harms AS, Ferreira SA, Romero-Ramos M. Periphery and brain, innate and adaptive immunity in Parkinson's disease. Acta Neuropathologica. PMID 33555429 DOI: 10.1007/s00401-021-02268-5  0.487
2020 Sulzer D, Antonini A, Leta V, Nordvig A, Smeyne RJ, Goldman JE, Al-Dalahmah O, Zecca L, Sette A, Bubacco L, Meucci O, Moro E, Harms AS, Xu Y, Fahn S, et al. COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside. Npj Parkinson's Disease. 6: 18. PMID 33574316 DOI: 10.1038/s41531-020-00123-0  0.337
2020 Harms AS, Kordower JH, Sette A, Lindestam Arlehamn CS, Sulzer D, Mach RH. Inflammation in Experimental Models of α-Synucleinopathies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33009855 DOI: 10.1002/mds.28264  0.372
2020 Sulzer D, Antonini A, Leta V, Nordvig A, Smeyne RJ, Goldman JE, Al-Dalahmah O, Zecca L, Sette A, Bubacco L, Meucci O, Moro E, Harms AS, Xu Y, Fahn S, et al. COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside. Npj Parkinson's Disease. 6: 18. PMID 32885037 DOI: 10.1038/S41531-020-00123-0  0.337
2020 Schonhoff AM, Williams GP, Wallen ZD, Standaert DG, Harms AS. Innate and adaptive immune responses in Parkinson's disease. Progress in Brain Research. 252: 169-216. PMID 32247364 DOI: 10.1016/bs.pbr.2019.10.006  0.814
2020 Williams GP, Marmion DJ, Schonhoff AM, Jurkuvenaite A, Won WJ, Standaert DG, Kordower JH, Harms AS. T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease. Acta Neuropathologica. PMID 31993745 DOI: 10.1007/S00401-020-02126-W  0.796
2018 Schonhoff AM, Harms AS. Glial GLP1R: A novel neuroprotector? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30427545 DOI: 10.1002/mds.27547  0.751
2018 Williams GP, Schonhoff AM, Jurkuvenaite A, Thome AD, Standaert DG, Harms AS. Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease. Journal of Neuroinflammation. 15: 244. PMID 30165873 DOI: 10.1186/S12974-018-1286-2  0.805
2017 Harms AS, Delic V, Thome AD, Bryant N, Liu Z, Chandra S, Jurkuvenaite A, West AB. α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration. Acta Neuropathologica Communications. 5: 85. PMID 29162163 DOI: 10.1186/S40478-017-0494-9  0.757
2017 Harms AS, Thome AD, Yan Z, Schonhoff AM, Williams GP, Li X, Liu Y, Qin H, Benveniste EN, Standaert DG. Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease. Experimental Neurology. PMID 29155051 DOI: 10.1016/j.expneurol.2017.11.010  0.817
2016 Qin H, Buckley JA, Li X, Liu Y, Fox TH, Meares GP, Yu H, Yan Z, Harms AS, Li Y, Standaert DG, Benveniste EN. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5144-59. PMID 27147665 DOI: 10.1523/Jneurosci.4658-15.2016  0.715
2016 Volpicelli-Daley LA, Kirik D, Stoyka LE, Standaert DG, Harms AS. How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson disease? Journal of Neurochemistry. PMID 27018978 DOI: 10.1111/Jnc.13627  0.798
2016 Thome AD, Harms AS, Volpicelli-Daley LA, Standaert DG. microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2383-90. PMID 26911687 DOI: 10.1523/Jneurosci.3900-15.2016  0.761
2016 Ponnazhagan R, Harms AS, Thome AD, Jurkuvenaite A, Gogliotti R, Niswender CM, Conn PJ, Standaert DG. The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 26872456 DOI: 10.1007/S11481-016-9655-Z  0.785
2015 Thome AD, Standaert DG, Harms AS. Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease. Plos One. 10: e0140566. PMID 26469270 DOI: 10.1371/journal.pone.0140566  0.813
2015 Benveniste E, Qin H, Harms A, Standaert D. ID: 163 Cytokine. 76: 64. DOI: 10.1016/J.Cyto.2015.08.038  0.722
2014 Lewis TB, Glasgow JN, Harms AS, Standaert DG, Curiel DT. Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses. 6: 3293-310. PMID 25196484 DOI: 10.3390/V6083293  0.719
2014 Harms AS, Standaert DG. Monocytes and Parkinson's disease: invaders from outside? Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1242. PMID 25124371 DOI: 10.1002/mds.25993  0.575
2013 Harms AS, Tansey MG. Isolation of murine postnatal brain microglia for phenotypic characterization using magnetic cell separation technology. Methods in Molecular Biology (Clifton, N.J.). 1041: 33-9. PMID 23813367 DOI: 10.1007/978-1-62703-520-0_5  0.53
2013 Harms AS, Cao S, Rowse AL, Thome AD, Li X, Mangieri LR, Cron RQ, Shacka JJ, Raman C, Standaert DG. MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9592-600. PMID 23739956 DOI: 10.1523/Jneurosci.5610-12.2013  0.832
2012 Cao S, Standaert DG, Harms AS. The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia. Journal of Neuroinflammation. 9: 259. PMID 23186369 DOI: 10.1186/1742-2094-9-259  0.726
2012 Harms AS, Lee JK, Nguyen TA, Chang J, Ruhn KM, Treviño I, Tansey MG. Regulation of microglia effector functions by tumor necrosis factor signaling. Glia. 60: 189-202. PMID 21989628 DOI: 10.1002/Glia.21254  0.739
2011 Harms AS, Barnum CJ, Ruhn KA, Varghese S, Treviño I, Blesch A, Tansey MG. Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 46-52. PMID 20959812 DOI: 10.1038/Mt.2010.217  0.823
2009 McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006  0.766
2009 Harms A, Varghese S, Ruhn K, Trevino I, Blesch A, Tansey M. P3.050 Role of tumor necrosis factor in the progressive phase of dopaminergic neuron death in a rat model of Parkinson's disease Parkinsonism & Related Disorders. 15: S161. DOI: 10.1016/S1353-8020(09)70614-5  0.585
2008 Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG. Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8517-28. PMID 18716210 DOI: 10.1523/Jneurosci.1806-08.2008  0.818
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