Jeffrey H. Kordower - Publications

Rush University, Chicago, IL, United States 
Neuroscience Biology

218 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Barker RA, Bjorklund A, Gash DM, Whone A, Van Laar A, Kordower JH, Bankiewicz K, Kieburtz K, Saarma M, Booms S, Huttunen HJ, Kells A, Fiandaca MS, Stoessl AJ, Eidelberg D, et al. GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop. Journal of Parkinson's Disease. PMID 32508331 DOI: 10.3233/JPD-202004  0.36
2020 Sellnow RC, Steece-Collier K, Altwal F, Sandoval IM, Kordower JH, Collier TJ, Sortwell CE, West AR, Manfredsson FP. Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32238479 DOI: 10.1523/JNEUROSCI.2936-19.2020  0.4
2020 Chu Y, Bartus RT, Manfredsson FP, Olanow CW, Kordower JH. Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease. Brain : a Journal of Neurology. 143: 960-975. PMID 32203581 DOI: 10.1093/brain/awaa020  0.6
2020 Espay AJ, Kalia LV, Gan-Or Z, Williams-Gray CH, Bedard PL, Rowe SM, Morgante F, Fasano A, Stecher B, Kauffman MA, Farrer MJ, Coffey CS, Schwarzschild MA, Sherer T, Postuma RB, ... ... Kordower JH, et al. Disease modification and biomarker development in Parkinson disease: Revision or reconstruction? Neurology. PMID 32102975 DOI: 10.1212/WNL.0000000000009107  0.44
2020 Williams GP, Marmion DJ, Schonhoff AM, Jurkuvenaite A, Won WJ, Standaert DG, Kordower JH, Harms AS. T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease. Acta Neuropathologica. PMID 31993745 DOI: 10.1007/s00401-020-02126-w  0.4
2019 Chu Y, Muller S, Tavares A, Barret O, Alagille D, Seibyl J, Tamagnan G, Marek K, Luk KC, Trojanowski JQ, Lee VMY, Kordower JH. Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes. Brain : a Journal of Neurology. PMID 31580415 DOI: 10.1093/brain/awz296  0.4
2019 Chatterjee D, Kordower JH. Immunotherapy in Parkinson's disease: Current status and future directions. Neurobiology of Disease. 104587. PMID 31454546 DOI: 10.1016/j.nbd.2019.104587  0.96
2019 Olanow CW, Savolainen M, Chu Y, Halliday GM, Kordower JH. Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease. Brain : a Journal of Neurology. PMID 31056668 DOI: 10.1093/brain/awz104  0.44
2019 Emerich DF, Kordower JH, Chu Y, Thanos C, Bintz B, Paolone G, Wahlberg LU. Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity. Neural Plasticity. 2019: 6286197. PMID 30984255 DOI: 10.1155/2019/6286197  0.48
2019 Chatterjee D, Sanchez DS, Quansah E, Rey NL, George S, Becker K, Madaj Z, Steiner JA, Ma J, Escobar Galvis ML, Kordower JH, Brundin P. Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy. Journal of Parkinson's Disease. PMID 30932894 DOI: 10.3233/JPD-191590  0.96
2018 Dodiya HB, Forsyth CB, Voigt RM, Engen PA, Patel J, Shaikh M, Green SJ, Naqib A, Roy A, Kordower JH, Pahan K, Shannon KM, Keshavarzian A. Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiology of Disease. PMID 30579705 DOI: 10.1016/j.nbd.2018.12.012  0.44
2018 Perez-Pardo P, Dodiya HB, Engen PA, Forsyth CB, Huschens AM, Shaikh M, Voigt RM, Naqib A, Green SJ, Kordower JH, Shannon KM, Garssen J, Kraneveld AD, Keshavarzian A. Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice. Gut. PMID 30554160 DOI: 10.1136/gutjnl-2018-316844  0.44
2018 Chatterjee D, Bhatt M, Butler D, De Genst E, Dobson CM, Messer A, Kordower JH. Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model. Npj Parkinson's Disease. 4: 25. PMID 30155513 DOI: 10.1038/s41531-018-0062-4  0.96
2018 Chu Y, Buchman AS, Olanow CW, Kordower JH. Do subjects with minimal motor features have prodromal PD? Annals of Neurology. PMID 29420861 DOI: 10.1002/ana.25179  0.44
2018 Manfredsson FP, Luk KC, Benskey MJ, Guezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology. Neurobiology of Disease. PMID 29341898 DOI: 10.1016/j.nbd.2018.01.008  0.4
2017 Mandel RJ, Marmion DJ, Kirik D, Chu Y, Heindel C, McCown T, Gray SJ, Kordower JH. Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates. Acta Neuropathologica Communications. 5: 47. PMID 28619074 DOI: 10.1186/s40478-017-0451-7  0.4
2017 Wakeman DR, Hiller BM, Marmion DJ, McMahon CW, Corbett GT, Mangan KP, Ma J, Little LE, Xie Z, Perez-Rosello T, Guzman JN, Surmeier DJ, Kordower JH. Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo. Stem Cell Reports. PMID 28579395 DOI: 10.1016/j.stemcr.2017.04.033  0.4
2017 Flavin WP, Bousset L, Green ZC, Chu Y, Skarpathiotis S, Chaney MJ, Kordower JH, Melki R, Campbell EM. Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins. Acta Neuropathologica. PMID 28527044 DOI: 10.1007/s00401-017-1722-x  0.4
2017 Marmion DJ, Kordower JH. α-Synuclein nonhuman primate models of Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 28434076 DOI: 10.1007/s00702-017-1720-0  0.4
2017 Engen PA, Dodiya HB, Naqib A, Forsyth CB, Green SJ, Voigt RM, Kordower JH, Mutlu EA, Shannon KM, Keshavarzian A. The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy. Journal of Parkinson's Disease. PMID 28234259 DOI: 10.3233/JPD-160991  0.44
2017 Olanow CW, Kordower JH. Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins. Movement Disorders : Official Journal of the Movement Disorder Society. 32: 203-207. PMID 28218461 DOI: 10.1002/mds.26935  0.44
2016 Kordower JH, Goetz CG, Chu Y, Halliday GM, Nicholson DA, Musial T, Marmion DJ, Stoessl AJ, Sossi V, Freeman TB, Olanow CW. Robust graft survival and normalized dopaminergic innervation does not obligate recovery in a pd patient. Annals of Neurology. PMID 27900791 DOI: 10.1002/ana.24820  0.44
2016 Kordower JH, Vinuela A, Chu Y, Isacson O, Redmond DE. Parkinsonian Monkeys With Prior Levodopa-Induced Dyskinesias Followed by Fetal Dopamine Precursor Grafts Do Not Display Graft-Induced Dyskinesias. The Journal of Comparative Neurology. PMID 27418401 DOI: 10.1002/cne.24081  0.4
2016 Brundin P, Ma J, Kordower JH. How strong is the evidence that Parkinson's disease is a prion disorder? Current Opinion in Neurology. PMID 27257944 DOI: 10.1097/WCO.0000000000000349  1
2016 Kordower JH, Olanow CW. Fetal grafts for Parkinson's disease: Decades in the making. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247420 DOI: 10.1073/pnas.1606342113  1
2016 Chu Y, Morfini GA, Kordower JH. Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease. Journal of Parkinson's Disease. PMID 27003787 DOI: 10.3233/JPD-160812  1
2016 Kordower JH. AAV2-Neurturin for Parkinson's Disease: What Lessons Have We Learned? Methods in Molecular Biology (Clifton, N.J.). 1382: 485-90. PMID 26611606 DOI: 10.1007/978-1-4939-3271-9_32  1
2015 Fung VS, Kordower JH. Parkinson's disease and prion disease: Straining the comparison. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1727. PMID 26769458 DOI: 10.1002/mds.26437  1
2015 Olanow CW, Bartus RT, Volpicelli-Daley LA, Kordower JH. Trophic factors for Parkinson's disease: To live or let die. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1715-24. PMID 26769457 DOI: 10.1002/mds.26426  0.6
2015 Keiser MS, Kordower JH, Gonzalez-Alegre P, Davidson BL. Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy. Brain : a Journal of Neurology. PMID 26490326 DOI: 10.1093/brain/awv292  1
2015 Dehay B, Vila M, Bezard E, Brundin P, Kordower JH. Alpha-synuclein propagation: New insights from animal models. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26347034 DOI: 10.1002/mds.26370  1
2015 Su X, Chu Y, Kordower JH, Li B, Cao H, Huang L, Nishida M, Song L, Wang D, Federoff HJ. PGC-1α Promoter Methylation in Parkinson's Disease. Plos One. 10: e0134087. PMID 26317511 DOI: 10.1371/journal.pone.0134087  1
2015 Corbett GT, Kordower JH. The native form of α-Synuclein: Monomer, tetramer, or a combination in equilibrium. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1870. PMID 26230906 DOI: 10.1002/mds.26361  1
2015 Gatto RG, Chu Y, Ye AQ, Price SD, Tavassoli E, Buenaventura A, Brady ST, Magin RL, Kordower JH, Morfini GA. Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Human Molecular Genetics. 24: 5285-98. PMID 26123489 DOI: 10.1093/hmg/ddv248  1
2015 Chu Y, Kordower JH. The prion hypothesis of Parkinson's disease. Current Neurology and Neuroscience Reports. 15: 28. PMID 25868519 DOI: 10.1007/s11910-015-0549-x  0.4
2015 Bartus RT, Kordower JH, Johnson EM, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies. Neurobiology of Disease. 78: 162-71. PMID 25841760 DOI: 10.1016/j.nbd.2015.03.023  1
2015 Roy A, Mondal S, Kordower JH, Pahan K. Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey. Neuroscience. PMID 25783477 DOI: 10.1016/j.neuroscience.2015.03.011  1
2015 Kordower JH. Gene therapy for Parkinson's disease: still a hot topic? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 255-6. PMID 25482182 DOI: 10.1038/npp.2014.235  1
2014 Olanow CW, Wakeman DR, Kordower JH. Peripheral alpha-synuclein and Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 963-6. PMID 25043799 DOI: 10.1002/mds.25966  1
2014 Kordower JH, Halliday G. Misfolded proteins in Huntington disease fetal grafts: further evidence of cell-to-cell transfer? Annals of Neurology. 76: 20-1. PMID 24961209 DOI: 10.1002/ana.24205  1
2014 Wakeman DR, Kordower JH. Special issue on stem cells. The Journal of Comparative Neurology. 522: 2689-90. PMID 24942075 DOI: 10.1002/cne.23611  1
2014 Kelly LP, Carvey PM, Keshavarzian A, Shannon KM, Shaikh M, Bakay RA, Kordower JH. Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 999-1009. PMID 24898698 DOI: 10.1002/mds.25736  1
2014 Kordower JH. The prion hypothesis of Parkinson's disease: this hot topic just got hotter. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 988. PMID 24867814 DOI: 10.1002/mds.25918  1
2014 Chu Y, Goldman JG, Kelly L, He Y, Waliczek T, Kordower JH. Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease. Neurobiology of Disease. 69: 1-14. PMID 24825319 DOI: 10.1016/j.nbd.2014.05.003  1
2014 Mattis VB, Wakeman DR, Tom C, Dodiya HB, Yeung SY, Tran AH, Bernau K, Ornelas L, Sahabian A, Reidling J, Sareen D, Thompson LM, Kordower JH, Svendsen CN. Neonatal immune-tolerance in mice does not prevent xenograft rejection. Experimental Neurology. 254: 90-8. PMID 24440640 DOI: 10.1016/j.expneurol.2014.01.007  1
2014 Rafii MS, Baumann TL, Bakay RA, Ostrove JM, Siffert J, Fleisher AS, Herzog CD, Barba D, Pay M, Salmon DP, Chu Y, Kordower JH, Bishop K, Keator D, Potkin S, et al. A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 571-81. PMID 24411134 DOI: 10.1016/j.jalz.2013.09.004  1
2013 Bhatt MA, Messer A, Kordower JH. Can intrabodies serve as neuroprotective therapies for Parkinson's disease? Beginning thoughts. Journal of Parkinson's Disease. 3: 581-91. PMID 24270241 DOI: 10.3233/JPD-130252  1
2013 Kordower JH. In memorium: Roy A.E. Bakay, MD. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1809-10. PMID 24150793 DOI: 10.1002/mds.25733  1
2013 Roy A, Jana M, Corbett GT, Ramaswamy S, Kordower JH, Gonzalez FJ, Pahan K. Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α. Cell Reports. 4: 724-37. PMID 23972989 DOI: 10.1016/j.celrep.2013.07.028  1
2013 Kordower JH, Olanow CW, Dodiya HB, Chu Y, Beach TG, Adler CH, Halliday GM, Bartus RT. Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain : a Journal of Neurology. 136: 2419-31. PMID 23884810 DOI: 10.1093/brain/awt192  1
2013 Cederfjäll E, Nilsson N, Sahin G, Chu Y, Nikitidou E, Björklund T, Kordower JH, Kirik D. Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease. Scientific Reports. 3: 2157. PMID 23831692 DOI: 10.1038/srep02157  1
2013 Bjorklund A, Kordower JH. Cell therapy for Parkinson's disease: what next? Movement Disorders : Official Journal of the Movement Disorder Society. 28: 110-5. PMID 23390097 DOI: 10.1002/mds.25343  1
2013 Kordower JH, Bjorklund A. Trophic factor gene therapy for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 96-109. PMID 23390096 DOI: 10.1002/mds.25344  1
2013 Tavares AA, Batis J, Barret O, Alagille D, Vala C, Kudej G, Koren A, Cosgrove KP, Nice K, Kordower JH, Seibyl J, Tamagnan GD. In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain. Nuclear Medicine and Biology. 40: 403-9. PMID 23332393 DOI: 10.1016/j.nucmedbio.2012.12.005  1
2013 Tavares AA, Barret O, Batis J, Alagille D, Koren A, Papin C, Kudej G, Nice K, Kordower JH, Cosgrove KP, Kloczynski T, Brenner E, Seibyl J, Tamagnan G. Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with (123)I-INER. Synapse (New York, N.Y.). 67: 30-41. PMID 23042643 DOI: 10.1002/syn.21613  1
2012 Brundin P, Kordower JH. Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy. Progress in Brain Research. 200: 221-41. PMID 23195421 DOI: 10.1016/B978-0-444-59575-1.00010-7  1
2012 Kordower JH, Kirik D. Introduction: gene therapy has gone from a pipe dream to clinical reality. Neurobiology of Disease. 48: 151-2. PMID 22841531 DOI: 10.1016/j.nbd.2012.07.014  1
2012 Wayman WN, Dodiya HB, Persons AL, Kashanchi F, Kordower JH, Hu XT, Napier TC. Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat. Neuroreport. 23: 825-9. PMID 22828409 DOI: 10.1097/WNR.0b013e3283578050  1
2012 Chu Y, Morfini GA, Langhamer LB, He Y, Brady ST, Kordower JH. Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease. Brain : a Journal of Neurology. 135: 2058-73. PMID 22719003 DOI: 10.1093/brain/aws133  1
2012 Mondal S, Roy A, Jana A, Ghosh S, Kordower JH, Pahan K. Testing NF-κB-based therapy in hemiparkinsonian monkeys. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 544-56. PMID 22661311 DOI: 10.1007/s11481-012-9377-9  1
2012 Shannon KM, Keshavarzian A, Dodiya HB, Jakate S, Kordower JH. Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 716-9. PMID 22550057 DOI: 10.1002/mds.25020  1
2012 Ramaswamy S, Kordower JH. Gene therapy for Huntington's disease. Neurobiology of Disease. 48: 243-54. PMID 22222669 DOI: 10.1016/j.nbd.2011.12.030  1
2012 Thompson VB, Koprich JB, Chen EY, Kordower JH, Terpstra BT, Lipton JW. Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat. Neurotoxicology and Teratology. 34: 206-13. PMID 21978916 DOI: 10.1016/  1
2012 Shannon KM, Keshavarzian A, Mutlu E, Dodiya HB, Daian D, Jaglin JA, Kordower JH. Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 709-15. PMID 21766334 DOI: 10.1002/mds.23838  1
2011 Herzog CD, Bishop KM, Brown L, Wilson A, Kordower JH, Bartus RT. Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases. Drug Delivery and Translational Research. 1: 361-82. PMID 25788422 DOI: 10.1007/s13346-011-0037-z  1
2011 Forsyth CB, Shannon KM, Kordower JH, Voigt RM, Shaikh M, Jaglin JA, Estes JD, Dodiya HB, Keshavarzian A. Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. Plos One. 6: e28032. PMID 22145021 DOI: 10.1371/journal.pone.0028032  1
2011 Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature. 480: 547-51. PMID 22056989 DOI: 10.1038/nature10648  1
2011 Mickiewicz AL, Kordower JH. GDNF family ligands: a potential future for Parkinson's disease therapy. Cns & Neurological Disorders Drug Targets. 10: 703-11. PMID 21838676  1
2011 Bartus RT, Brown L, Wilson A, Kruegel B, Siffert J, Johnson EM, Kordower JH, Herzog CD. Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease. Neurobiology of Disease. 44: 38-52. PMID 21704161 DOI: 10.1016/j.nbd.2011.05.026  1
2011 Kordower JH, Dodiya HB, Kordower AM, Terpstra B, Paumier K, Madhavan L, Sortwell C, Steece-Collier K, Collier TJ. Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat. Neurobiology of Disease. 43: 552-7. PMID 21600984 DOI: 10.1016/j.nbd.2011.05.001  1
2011 Collier TJ, Kanaan NM, Kordower JH. Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates. Nature Reviews. Neuroscience. 12: 359-66. PMID 21587290 DOI: 10.1038/nrn3039  1
2011 Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Siffert J, Johnson EM, Olanow CW, Mufson EJ, Kordower JH. Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 27-36. PMID 21322017 DOI: 10.1002/mds.23442  1
2011 Wakeman DR, Dodiya HB, Kordower JH. Cell transplantation and gene therapy in Parkinson's disease. The Mount Sinai Journal of Medicine, New York. 78: 126-58. PMID 21259269 DOI: 10.1002/msj.20233  1
2011 Chu Y, Mickiewicz AL, Kordower JH. α-synuclein aggregation reduces nigral myocyte enhancer factor-2D in idiopathic and experimental Parkinson's disease. Neurobiology of Disease. 41: 71-82. PMID 20816781 DOI: 10.1016/j.nbd.2010.08.022  1
2011 Merrill DA, Masliah E, Roberts JA, McKay H, Kordower JH, Mufson EJ, Tuszynski MH. Association of early experience with neurodegeneration in aged primates. Neurobiology of Aging. 32: 151-6. PMID 19321231 DOI: 10.1016/j.neurobiolaging.2009.01.014  1
2011 Soderstrom KE, Ramaswamy S, Olanow CW, Kordower JH. Animal Models of Parkinson's Disease: The Non-Motor and Non-Dopaminergic Features Parkinson's Disease: Non-Motor and Non-Dopaminergic Features. 79-92. DOI: 10.1002/9781444397970.ch7  1
2010 Marks WJ, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, ... ... Kordower JH, et al. Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial. The Lancet. Neurology. 9: 1164-72. PMID 20970382 DOI: 10.1016/S1474-4422(10)70254-4  1
2010 Rangasamy SB, Soderstrom K, Bakay RA, Kordower JH. Neurotrophic factor therapy for Parkinson's disease. Progress in Brain Research. 184: 237-64. PMID 20887879 DOI: 10.1016/S0079-6123(10)84013-0  1
2010 Cai Y, Xiong K, Zhang XM, Cai H, Luo XG, Feng JC, Clough RW, Struble RG, Patrylo PR, Chu Y, Kordower JH, Yan XX. β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation. The European Journal of Neuroscience. 32: 1223-38. PMID 20726888 DOI: 10.1111/j.1460-9568.2010.07376.x  1
2010 Obeso JA, Rodriguez-Oroz MC, Goetz CG, Marin C, Kordower JH, Rodriguez M, Hirsch EC, Farrer M, Schapira AH, Halliday G. Missing pieces in the Parkinson's disease puzzle. Nature Medicine. 16: 653-61. PMID 20495568 DOI: 10.1038/nm.2165  1
2010 Kordower JH, Chen EY, Morrison JH. Long-term gonadal hormone treatment and endogenous neurogenesis in the dentate gyrus of the adult female monkey. Experimental Neurology. 224: 252-7. PMID 20362573 DOI: 10.1016/j.expneurol.2010.03.027  1
2010 Han I, You Y, Kordower JH, Brady ST, Morfini GA. Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features. Journal of Neurochemistry. 113: 1073-91. PMID 20236390 DOI: 10.1111/j.1471-4159.2010.06672.x  1
2010 Bjorklund T, Kordower JH. Gene therapy for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S161-73. PMID 20187249 DOI: 10.1002/mds.22785  1
2010 Chu Y, Kordower JH. Lewy body pathology in fetal grafts. Annals of the New York Academy of Sciences. 1184: 55-67. PMID 20146690 DOI: 10.1111/j.1749-6632.2009.05229.x  1
2010 Dodiya HB, Bjorklund T, Stansell J, Mandel RJ, Kirik D, Kordower JH. Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 579-87. PMID 19773746 DOI: 10.1038/mt.2009.216  1
2010 Emerich DF, Mooney DJ, Storrie H, Babu RS, Kordower JH. Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease. Neurotoxicity Research. 17: 66-74. PMID 19588214 DOI: 10.1007/s12640-009-9079-0  1
2010 Kanaan NM, Kordower JH, Collier TJ. Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys. Neurobiology of Aging. 31: 937-52. PMID 18715678 DOI: 10.1016/j.neurobiolaging.2008.07.006  1
2010 Kordower JH, Halliday G, Obeso JA. Kordower, Halliday and Obeso reply Nature Medicine. 16: 961. DOI: 10.1038/nm0910-961a  1
2010 Chen EY, Fox D, Kordower JH. Neurotrophic factor therapy: GDNF and CNTF Encyclopedia of Neuroscience. 1085-1092. DOI: 10.1016/B978-008045046-9.00015-2  1
2009 Ramaswamy S, Kordower JH. Are growth factors the answer? Parkinsonism & Related Disorders. 15: S176-80. PMID 20082985 DOI: 10.1016/S1353-8020(09)70809-0  1
2009 Olanow CW, Kordower JH, Lang AE, Obeso JA. Dopaminergic transplantation for Parkinson's disease: current status and future prospects. Annals of Neurology. 66: 591-6. PMID 19938101 DOI: 10.1002/ana.21778  1
2009 Zhang XM, Cai Y, Chu Y, Chen EY, Feng JC, Luo XG, Xiong K, Struble RG, Clough RW, Patrylo PR, Kordower JH, Yan XX. Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Frontiers in Neuroanatomy. 3: 17. PMID 19862344 DOI: 10.3389/neuro.05.017.2009  1
2009 Olanow CW, Kordower JH. Modeling Parkinson's disease. Annals of Neurology. 66: 432-6. PMID 19847894 DOI: 10.1002/ana.21832  1
2009 Mak SK, McCormack AL, Langston JW, Kordower JH, Di Monte DA. Decreased alpha-synuclein expression in the aging mouse substantia nigra. Experimental Neurology. 220: 359-65. PMID 19800328 DOI: 10.1016/j.expneurol.2009.09.021  1
2009 Kordower JH, Brundin P. Propagation of host disease to grafted neurons: accumulating evidence. Experimental Neurology. 220: 224-5. PMID 19786018 DOI: 10.1016/j.expneurol.2009.09.016  1
2009 Kordower JH. Animal rights terrorists: what every neuroscientist should know. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11419-20. PMID 19759289 DOI: 10.1523/JNEUROSCI.3764-09.2009  1
2009 Ramaswamy S, Soderstrom KE, Kordower JH. Trophic factors therapy in Parkinson's disease. Progress in Brain Research. 175: 201-16. PMID 19660658 DOI: 10.1016/S0079-6123(09)17514-3  1
2009 Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiology of Disease. 36: 303-11. PMID 19660547 DOI: 10.1016/j.nbd.2009.07.022  1
2009 Cicchetti F, Saporta S, Hauser RA, Parent M, Saint-Pierre M, Sanberg PR, Li XJ, Parker JR, Chu Y, Mufson EJ, Kordower JH, Freeman TB. Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 106: 12483-8. PMID 19620721 DOI: 10.1073/pnas.0904239106  1
2009 Chu Y, Dodiya H, Aebischer P, Olanow CW, Kordower JH. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. Neurobiology of Disease. 35: 385-98. PMID 19505575 DOI: 10.1016/j.nbd.2009.05.023  1
2009 Sladek JR, Sanberg P, Kordower JH. Celebrating neural repair. The Journal of Comparative Neurology. 515: 1-3. PMID 19399900 DOI: 10.1002/cne.22036  1
2009 Herzog CD, Brown L, Gammon D, Kruegel B, Lin R, Wilson A, Bolton A, Printz M, Gasmi M, Bishop KM, Kordower JH, Bartus RT. Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease. Neurosurgery. 64: 602-12; discussion 6. PMID 19349823 DOI: 10.1227/01.NEU.0000340682.06068.01  1
2009 Cai Y, Xiong K, Chu Y, Luo DW, Luo XG, Yuan XY, Struble RG, Clough RW, Spencer DD, Williamson A, Kordower JH, Patrylo PR, Yan XX. Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups. Experimental Neurology. 216: 342-56. PMID 19166833 DOI: 10.1016/j.expneurol.2008.12.008  1
2009 Ramaswamy S, McBride JL, Han I, Berry-Kravis EM, Zhou L, Herzog CD, Gasmi M, Bartus RT, Kordower JH. Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease. Neurobiology of Disease. 34: 40-50. PMID 19150499 DOI: 10.1016/j.nbd.2008.12.005  1
2009 Kordower JH, Brundin P. Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 254. PMID 19079079 DOI: 10.1038/npp.2008.161  1
2009 Olanow CW, Gracies JM, Goetz CG, Stoessl AJ, Freeman T, Kordower JH, Godbold J, Obeso JA. Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 336-43. PMID 19006186 DOI: 10.1002/mds.22208  1
2009 Babu RS, Mungre S, Kordower JH, Sethu G, Sridevi D, Periasamy P, Namasivayam A. Recovery of functions after spinal cord injury in bonnet macaques: Behavioral analysis Handbook of Spinal Cord Injuries: Types, Treatments and Prognosis. 1-131.  1
2008 Isacson O, Kordower JH. Future of cell and gene therapies for Parkinson's disease. Annals of Neurology. 64: S122-38. PMID 19127583 DOI: 10.1002/ana.21473  1
2008 Kordower JH, Chu Y, Hauser RA, Olanow CW, Freeman TB. Transplanted dopaminergic neurons develop PD pathologic changes: a second case report. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 2303-6. PMID 19006193 DOI: 10.1002/mds.22369  1
2008 Herzog CD, Dass B, Gasmi M, Bakay R, Stansell JE, Tuszynski M, Bankiewicz K, Chen EY, Chu Y, Bishop K, Kordower JH, Bartus RT. Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1737-44. PMID 18728639 DOI: 10.1038/mt.2008.170  1
2008 Kanaan NM, Kordower JH, Collier TJ. Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration. The European Journal of Neuroscience. 27: 3205-15. PMID 18598263 DOI: 10.1111/j.1460-9568.2008.06307.x  1
2008 Kordower JH. Introduction to the special ASNTR issue. Cell Transplantation. 17: 361-2. PMID 18522238  1
2008 Kanaan NM, Kordower JH, Collier TJ. Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys. Glia. 56: 1199-214. PMID 18484101 DOI: 10.1002/glia.20690  1
2008 Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nature Medicine. 14: 504-6. PMID 18391962 DOI: 10.1038/nm1747  1
2008 Redmond DE, Vinuela A, Kordower JH, Isacson O. Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease. Neurobiology of Disease. 29: 103-16. PMID 17920901 DOI: 10.1016/j.nbd.2007.08.008  1
2008 Kordower JH, Olanow CW. Regulatable promoters and gene therapy for Parkinson's disease: is the only thing to fear, fear itself? Experimental Neurology. 209: 34-40. PMID 17888424 DOI: 10.1016/j.expneurol.2007.08.001  1
2008 Ramaswamy S, Kordower JH. Gene and cellular transplantation therapies for huntington's disease Cns Regeneration. 267-294. DOI: 10.1016/B978-012373994-0.50013-0  1
2008 Chu Y, Kordower JH. The use of Aged Monkeys to Study PD: Important Roles in Pathogenesis and Experimental Therapeutics Parkinson's Disease. 77-85. DOI: 10.1016/B978-0-12-374028-1.00007-5  1
2008 Kordower JH, Tuszynski MH. CNS Regeneration Cns Regeneration 1
2007 Dass B, Kordower JH. Gene therapy approaches for the treatment of Parkinson's disease. Handbook of Clinical Neurology. 84: 291-304. PMID 18808954 DOI: 10.1016/S0072-9752(07)84045-0  1
2007 Bartus RT, Herzog CD, Bishop K, Ostrove JM, Tuszynski M, Kordower JH, Gasmi M. Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point. Parkinsonism & Related Disorders. 13: S469-77. PMID 18267286 DOI: 10.1016/S1353-8020(08)70052-X  1
2007 Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K. Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 18754-9. PMID 18000063 DOI: 10.1073/pnas.0704908104  1
2007 Sani S, Jobe K, Smith A, Kordower JH, Bakay RA. Deep brain stimulation for treatment of obesity in rats. Journal of Neurosurgery. 107: 809-13. PMID 17937228 DOI: 10.3171/JNS-07/10/0809  1
2007 Ramaswamy S, McBride JL, Kordower JH. Animal models of Huntington's disease. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 48: 356-73. PMID 17712222  1
2007 Kompoliti K, Chu Y, Shannon KM, Kordower JH. Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1630-3. PMID 17534949 DOI: 10.1002/mds.21528  1
2007 Gasmi M, Brandon EP, Herzog CD, Wilson A, Bishop KM, Hofer EK, Cunningham JJ, Printz MA, Kordower JH, Bartus RT. AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease. Neurobiology of Disease. 27: 67-76. PMID 17532642 DOI: 10.1016/j.nbd.2007.04.003  1
2007 Ramaswamy S, Shannon KM, Kordower JH. Huntington's disease: pathological mechanisms and therapeutic strategies. Cell Transplantation. 16: 301-12. PMID 17503740  1
2007 Herzog CD, Dass B, Holden JE, Stansell J, Gasmi M, Tuszynski MH, Bartus RT, Kordower JH. Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1124-32. PMID 17443702 DOI: 10.1002/mds.21503  1
2007 Kanaan NM, Kordower JH, Collier TJ. Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability. The Journal of Comparative Neurology. 502: 683-700. PMID 17436290 DOI: 10.1002/cne.21333  1
2007 Marchionini DM, Lehrmann E, Chu Y, He B, Sortwell CE, Becker KG, Freed WJ, Kordower JH, Collier TJ. Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease. Brain Research. 1147: 77-88. PMID 17368428 DOI: 10.1016/j.brainres.2007.02.028  1
2007 Ramaswamy S, McBride JL, Herzog CD, Brandon E, Gasmi M, Bartus RT, Kordower JH. Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease. Neurobiology of Disease. 26: 375-84. PMID 17336076 DOI: 10.1016/j.nbd.2007.01.003  1
2007 Collier TJ, Lipton J, Daley BF, Palfi S, Chu Y, Sortwell C, Bakay RA, Sladek JR, Kordower JH. Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism. Neurobiology of Disease. 26: 56-65. PMID 17254792 DOI: 10.1016/j.nbd.2006.11.013  1
2007 Chu Y, Kordower JH. Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease? Neurobiology of Disease. 25: 134-49. PMID 17055279 DOI: 10.1016/j.nbd.2006.08.021  1
2006 Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J, Gasmi M, Bartus RT. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Annals of Neurology. 60: 706-15. PMID 17192932 DOI: 10.1002/ana.21032  1
2006 Roitberg BZ, Mangubat E, Chen EY, Sugaya K, Thulborn KR, Kordower JH, Pawar A, Konecny T, Emborg ME. Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke. Journal of Neurosurgery. 105: 96-102. PMID 16871883 DOI: 10.3171/jns.2006.105.1.96  1
2006 Bové J, Zhou C, Jackson-Lewis V, Taylor J, Chu Y, Rideout HJ, Wu DC, Kordower JH, Petrucelli L, Przedborski S. Proteasome inhibition and Parkinson's disease modeling. Annals of Neurology. 60: 260-4. PMID 16862585 DOI: 10.1002/ana.20937  1
2006 Kordower JH, Kanaan NM, Chu Y, Suresh Babu R, Stansell J, Terpstra BT, Sortwell CE, Steece-Collier K, Collier TJ. Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys. Annals of Neurology. 60: 264-8. PMID 16862579 DOI: 10.1002/ana.20935  1
2006 Emerich DF, Thanos CG, Goddard M, Skinner SJ, Geany MS, Bell WJ, Bintz B, Schneider P, Chu Y, Babu RS, Borlongan CV, Boekelheide K, Hall S, Bryant B, Kordower JH. Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys. Neurobiology of Disease. 23: 471-80. PMID 16777422 DOI: 10.1016/j.nbd.2006.04.014  1
2006 Emborg ME, Moirano J, Schafernak KT, Moirano M, Evans M, Konecny T, Roitberg B, Ambarish P, Mangubat E, Ma Y, Eidelberg D, Holden J, Kordower JH, Leestma JE. Basal ganglia lesions after MPTP administration in rhesus monkeys. Neurobiology of Disease. 23: 281-9. PMID 16766201 DOI: 10.1016/j.nbd.2006.03.010  1
2006 McBride JL, Ramaswamy S, Gasmi M, Bartus RT, Herzog CD, Brandon EP, Zhou L, Pitzer MR, Berry-Kravis EM, Kordower JH. Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 9345-50. PMID 16751280 DOI: 10.1073/pnas.0508875103  1
2006 Soderstrom K, O'Malley J, Steece-Collier K, Kordower JH. Neural repair strategies for Parkinson's disease: insights from primate models. Cell Transplantation. 15: 251-65. PMID 16719060 DOI: 10.3727/000000006783982025  1
2006 Dass B, Olanow CW, Kordower JH. Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease. Neurology. 66: S89-103. PMID 16717256  1
2006 Rissman RA, Nocera R, Fuller LM, Kordower JH, Armstrong DM. Age-related alterations in GABA(A) receptor subunits in the nonhuman primate hippocampus. Brain Research. 1073: 120-30. PMID 16430870 DOI: 10.1016/j.brainres.2005.12.036  1
2006 Schneider JA, Li JL, Li Y, Wilson RS, Kordower JH, Bennett DA. Substantia nigra tangles are related to gait impairment in older persons. Annals of Neurology. 59: 166-73. PMID 16374822 DOI: 10.1002/ana.20723  1
2006 Chu Y, Le W, Kompoliti K, Jankovic J, Mufson EJ, Kordower JH. Nurr1 in Parkinson's disease and related disorders. The Journal of Comparative Neurology. 494: 495-514. PMID 16320253 DOI: 10.1002/cne.20828  1
2006 Maries E, Kordower JH, Chu Y, Collier TJ, Sortwell CE, Olaru E, Shannon K, Steece-Collier K. Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats. Neurobiology of Disease. 21: 165-80. PMID 16095907 DOI: 10.1016/j.nbd.2005.07.002  1
2006 Dass B, Kladis T, Chu Y, Kordower JH. RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys. Neurobiology of Aging. 27: 857-61. PMID 15950322 DOI: 10.1016/j.neurobiolaging.2005.04.002  1
2006 Sortwell CE, Kordower JH. In vivo gene therapy as a potential treatment for Parkinson's disease Restorative Therapies in Parkinson's Disease. 317-344. DOI: 10.1007/0-387-32823-2_16  1
2005 Counts SE, Chen EY, Ginsberg SD, Kordower JH, Mufson EJ. RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus. Journal of Neuroscience Methods. 144: 197-201. PMID 15910978 DOI: 10.1016/j.jneumeth.2004.11.005  1
2005 Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, ... Kordower JH, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nature Medicine. 11: 551-5. PMID 15852017 DOI: 10.1038/nm1239  1
2005 Collier TJ, Dung Ling Z, Carvey PM, Fletcher-Turner A, Yurek DM, Sladek JR, Kordower JH. Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism. Experimental Neurology. 191: S60-7. PMID 15629762 DOI: 10.1016/j.expneurol.2004.08.018  1
2005 Collier TJ, Kordower JH. John R. Sladek Jr., Ph.D.: In celebration of 15 years of editorial service Experimental Neurology. 191: S1-S2. DOI: 10.1016/j.expneurol.2004.09.001  1
2004 Diprospero NA, Chen EY, Charles V, Plomann M, Kordower JH, Tagle DA. Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements Journal of Neurocytology. 33: 517-533. PMID 15906159 DOI: 10.1007/s11068-004-0514-8  1
2004 Perez S, Sendera TJ, Kordower JH, Mufson EJ. Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase. Brain Research. 1019: 55-63. PMID 15306238 DOI: 10.1016/j.brainres.2004.05.101  1
2004 McBride JL, Behrstock SP, Chen EY, Jakel RJ, Siegel I, Svendsen CN, Kordower JH. Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. The Journal of Comparative Neurology. 475: 211-9. PMID 15211462 DOI: 10.1002/cne.20176  1
2004 Freed CR, Breeze RE, Fahn S, Eidelberg D. Preoperative response to levodopa is the best predictor of transplant outcome. Annals of Neurology. 55: 896; author reply 89. PMID 15174028 DOI: 10.1002/ana.20085  1
2004 Kompoliti K, Chu Y, Polish A, Roberts J, McKay H, Mufson EJ, Leurgans S, Morrison JH, Kordower JH. Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys. The Journal of Comparative Neurology. 472: 193-207. PMID 15048687 DOI: 10.1002/cne.20050  1
2004 Tang Y, Janssen WG, Hao J, Roberts JA, McKay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH. Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys. Cerebral Cortex (New York, N.Y. : 1991). 14: 215-23. PMID 14704219 DOI: 10.1093/cercor/bhg121  1
2003 Collier TJ, Steece-Collier K, Kordower JH. Primate models of Parkinson's disease. Experimental Neurology. 183: 258-62. PMID 14552866 DOI: 10.1016/S0014-4886(03)00246-2  1
2003 Hao J, Janssen WG, Tang Y, Roberts JA, McKay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH. Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys. The Journal of Comparative Neurology. 465: 540-50. PMID 12975814 DOI: 10.1002/cne.10837  1
2003 Koprich JB, Chen EY, Kanaan NM, Campbell NG, Kordower JH, Lipton JW. Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) alters exploratory behavior, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of juvenile rats. Neurotoxicology and Teratology. 25: 509-17. PMID 12972064 DOI: 10.1016/S0892-0362(03)00091-6  1
2003 Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, Brin MF, Shannon KM, Nauert GM, Perl DP, Godbold J, Freeman TB. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Annals of Neurology. 54: 403-14. PMID 12953276 DOI: 10.1002/ana.10720  1
2003 Maries E, Dass B, Collier TJ, Kordower JH, Steece-Collier K. The role of alpha-synuclein in Parkinson's disease: insights from animal models. Nature Reviews. Neuroscience. 4: 727-38. PMID 12951565 DOI: 10.1038/nrn1199  1
2003 Kus L, Borys E, Ping Chu Y, Ferguson SM, Blakely RD, Emborg ME, Kordower JH, Levey AI, Mufson EJ. Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system. The Journal of Comparative Neurology. 463: 341-57. PMID 12820166 DOI: 10.1002/cne.10759  1
2003 Hanbury R, Chen EY, Wuu J, Kordower JH. Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury. Journal of Molecular Neuroscience : Mn. 20: 93-102. PMID 12794303 DOI: 10.1385/JMN:20:2:93  1
2003 McBride JL, During MJ, Wuu J, Chen EY, Leurgans SE, Kordower JH. Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF. Experimental Neurology. 181: 213-23. PMID 12781994 DOI: 10.1016/S0014-4886(03)00044-X  1
2003 Hanbury R, Ling ZD, Wuu J, Kordower JH. GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults. The Journal of Comparative Neurology. 461: 307-16. PMID 12746870 DOI: 10.1002/cne.10667  1
2003 Salzberg-Brenhouse HC, Chen EY, Emerich DF, Baldwin S, Hogeland K, Ranelli S, Lafreniere D, Perdomo B, Novak L, Kladis T, Fu K, Basile AS, Kordower JH, Bartus RT. Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. The Journal of Pharmacology and Experimental Therapeutics. 306: 218-28. PMID 12676885 DOI: 10.1124/jpet.103.049700  1
2003 Kordower JH, Isacson, Brooks, Olanow, Hunot, Stocchi, Jenner, Rascol, Marek. In vivo gene delivery of glial cell line-derived neurotrophic factor for Parkinson's disease Annals of Neurology. 53. PMID 12666104 DOI: 10.1002/ana.10485  1
2003 Roitberg B, Khan N, Tuccar E, Kompoliti K, Chu Y, Alperin N, Kordower JH, Emborg ME. Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study. Neurological Research. 25: 68-78. PMID 12564129 DOI: 10.1179/016164103101200950  1
2002 Eberling JL, Pivirotto P, Bringas J, Steiner JP, Kordower JH, Chu Y, Emborg ME, Bankiewicz KS. The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys. Experimental Neurology. 178: 236-42. PMID 12504882 DOI: 10.1006/exnr.2002.8023  1
2002 McBride JL, Kordower JH. Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF. Progress in Brain Research. 138: 421-32. PMID 12432782 DOI: 10.1016/S0079-6123(02)38091-9  1
2002 Steece-Collier K, Maries E, Kordower JH. Etiology of Parkinson's disease: Genetics and environment revisited Proceedings of the National Academy of Sciences of the United States of America. 99: 13972-13974. PMID 12391311 DOI: 10.1073/pnas.242594999  1
2002 Chu Y, Kompoliti K, Cochran EJ, Mufson EJ, Kordower JH. Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. The Journal of Comparative Neurology. 450: 203-14. PMID 12209851 DOI: 10.1002/cne.10261  1
2002 Palfi S, Leventhal L, Chu Y, Ma SY, Emborg M, Bakay R, Déglon N, Hantraye P, Aebischer P, Kordower JH. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4942-54. PMID 12077191  1
2002 Hanbury R, Charles V, Chen EY, Leventhal L, Rosenstein JM, Mufson EJ, Kordower JH. Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors. The Journal of Comparative Neurology. 444: 291-305. PMID 11891644 DOI: 10.1002/cne.10104  1
2002 Roitberg BZ, Emborg ME, Sramek JG, Palfi S, Kordower JH. Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease. Neurosurgery. 50: 137-45; discussion 1. PMID 11844244 DOI: 10.1097/00006123-200201000-00022  1
2002 DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Annals of Neurology. 51: 145-55. PMID 11835370 DOI: 10.1002/ana.10069  1
2002 Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, Bennett DA, Jaffar S, Gilmor ML, Levey AI, Kordower JH. Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease. The Journal of Comparative Neurology. 443: 136-53. PMID 11793352 DOI: 10.1002/cne.10122  1
2001 Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH. Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease. The Journal of Comparative Neurology. 437: 296-307. PMID 11494257 DOI: 10.1002/cne.1284  1
2001 Guidetti P, Charles V, Chen EY, Reddy PH, Kordower JH, Whetsell WO, Schwarcz R, Tagle DA. Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production. Experimental Neurology. 169: 340-50. PMID 11358447 DOI: 10.1006/exnr.2000.7626  1
2001 Kordower JH, Aebischer P. Gene therapy to the rescue in Parkinson's disease: Response from Kordower and Aebischer Trends in Pharmacological Sciences. 22: 105-106. PMID 11239562 DOI: 10.1016/S0165-6147(00)01637-0  1
2001 Kordower JH, Chu Y, Stebbins GT, DeKosky ST, Cochran EJ, Bennett D, Mufson EJ. Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Annals of Neurology. 49: 202-13. PMID 11220740 DOI: 10.1002/1531-8249(20010201)49:2<202::AID-ANA40>3.0.CO;2-3  1
2001 Emborg ME, Shin P, Roitberg B, Sramek JG, Chu Y, Stebbins GT, Hamilton JS, Suzdak PD, Steiner JP, Kordower JH. Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys Experimental Neurology. 168: 171-182. PMID 11170732 DOI: 10.1006/exnr.2000.7592  1
2001 Emborg ME, Deglon N, Leventhal L, Aebischer P, Kordower JH. Viral vector-mediated gene therapy for Parkinson's disease Clinical Neuroscience Research. 1: 496-506. DOI: 10.1016/S1566-2772(01)00027-5  1
2000 Gurevich EV, Kordower JH, Joyce JN. Ontogeny of the dopamine D2 receptor mRNA expressing cells in the human hippocampal formation and temporal neocortex Journal of Chemical Neuroanatomy. 20: 307-325. PMID 11207428 DOI: 10.1016/S0891-0618(00)00108-3  1
2000 Kordower JH, Isacson O, Leventhal L, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Progress in Brain Research. 127: 414-30. PMID 11142039 DOI: 10.1016/S0079-6123(00)27020-9  1
2000 Kordower JH, Sortwell CE. Neuropathology of fetal nigra transplants for Parkinson's disease. Progress in Brain Research. 127: 333-44. PMID 11142034 DOI: 10.1016/S0079-6123(00)27016-7  1
2000 Freeman TB, Cicchetti F, Hauser RA, Deacon TW, Li XJ, Hersch SM, Nauert GM, Sanberg PR, Kordower JH, Saporta S, Isacson O. Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology. Proceedings of the National Academy of Sciences of the United States of America. 97: 13877-82. PMID 11106399 DOI: 10.1073/pnas.97.25.13877  1
2000 Emborg ME, Kordower JH. Delivery of therapeutic molecules into the CNS Progress in Brain Research. 128: 323-332. PMID 11105691 DOI: 10.1016/S0079-6123(00)28029-1  1
2000 Kordower JH. Making the counts count: The stereology revolution Journal of Chemical Neuroanatomy. 20: 1-2. PMID 11074338 DOI: 10.1016/S0891-0618(00)00079-X  1
2000 Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, Brown WD, Holden JE, Pyzalski R, Taylor MD, Carvey P, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (New York, N.Y.). 290: 767-73. PMID 11052933 DOI: 10.1126/science.290.5492.767  1
2000 Mufson EJ, Ma SY, Cochran EJ, Bennett DA, Beckett LA, Jaffar S, Saragovi HU, Kordower JH. Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease. The Journal of Comparative Neurology. 427: 19-30. PMID 11042589 DOI: 10.1002/1096-9861(20001106)427:1<19::AID-CNE2>3.0.CO;2-A  1
2000 Chen EY, Emerich DF, Bartus RT, Kordower JH. B2 bradykinin receptor immunoreactivity in rat brain. The Journal of Comparative Neurology. 427: 1-18. PMID 11042588 DOI: 10.1002/1096-9861(20001106)427:1<1::AID-CNE1>3.0.CO;2-0  1
2000 Chen EY, Kallwitz E, Leff SE, Cochran EJ, Mufson EJ, Kordower JH, Mandel RJ. Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra. The Journal of Comparative Neurology. 426: 534-48. PMID 11027397 DOI: 10.1002/1096-9861(20001030)426:4<534::AID-CNE3>3.0.CO;2-G  1
2000 Leventhal L, Sortwell CE, Hanbury R, Collier TJ, Kordower JH, Palfi S. Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity. The Journal of Comparative Neurology. 425: 471-8. PMID 10975874 DOI: 10.1002/1096-9861(20001002)425:4<471::AID-CNE1>3.0.CO;2-U  1
2000 Palfi S, Leventhal L, Goetz CG, Hantraye T, Roitberg BZ, Sramek J, Emborg M, Kordower JH. Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys. Movement Disorders : Official Journal of the Movement Disorder Society. 15: 524-30. PMID 10830419 DOI: 10.1002/1531-8257(200005)15:3<524::AID-MDS1016>3.0.CO;2-F  1
2000 Sendera TJ, Ma SY, Jaffar S, Kozlowski PB, Kordower JH, Mawal Y, Saragovi HU, Mufson EJ. Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome. Journal of Neurochemistry. 74: 1185-96. PMID 10693951  1
2000 Bartus RT, Snodgrass P, Dean RL, Kordower JH, Emerich DF. Evidence that Cereport's ability to increase permeability of rat gliomas is dependent upon extent of tumor growth: implications for treating newly emerging tumor colonies. Experimental Neurology. 161: 234-44. PMID 10683290 DOI: 10.1006/exnr.1999.7247  1
2000 Zimmer J, Kordower JH. Experimental Neurology: Proceedings of the 7th International Meeting on Neural Transplantation and Repair. Guest editorial Experimental Neurology. 164: 1. DOI: 10.1006/exnr.2000.7478  1
1999 Kordower JH, Goetz CG. The first miracle in neurodegenerative disease: The discovery of oral levodopa Brain Research Bulletin. 50: 377-378. PMID 10643443 DOI: 10.1016/S0361-9230(99)00112-4  1
1999 Kordower JH, Bloch J, Ma SY, Chu Y, Palfi S, Roitberg BZ, Emborg M, Hantraye P, Déglon N, Aebischer P. Lentiviral gene transfer to the nonhuman primate brain. Experimental Neurology. 160: 1-16. PMID 10630186 DOI: 10.1006/exnr.1999.7178  1
1999 Mufson EJ, Cai WJ, Jaffar S, Chen E, Stebbins G, Sendera T, Kordower JH. Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase. Brain Research. 849: 253-74. PMID 10592312 DOI: 10.1016/S0006-8993(99)01960-5  1
1999 Kordower JH, Isacson O, Emerich DF. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? Experimental Neurology. 159: 4-20. PMID 10486171 DOI: 10.1006/exnr.1999.7156  1
1999 Kordower JH, Palfi S, Chen EY, Ma SY, Sendera T, Cochran EJ, Cochran EJ, Mufson EJ, Penn R, Goetz CG, Comella CD. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Annals of Neurology. 46: 419-24. PMID 10482276 DOI: 10.1002/1531-8249(199909)46:3<419::AID-ANA21>3.0.CO;2-Q  1
1999 Mufson EJ, Chen EY, Cochran EJ, Beckett LA, Bennett DA, Kordower JH. Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment. Experimental Neurology. 158: 469-90. PMID 10415154 DOI: 10.1006/exnr.1999.7086  1
1999 Ma SY, Ciliax BJ, Stebbins G, Jaffar S, Joyce JN, Cochran EJ, Kordower JH, Mash DC, Levey AI, Mufson EJ. Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra. The Journal of Comparative Neurology. 409: 25-37. PMID 10363709 DOI: 10.1002/(SICI)1096-9861(19990621)409:1<25::AID-CNE3>3.0.CO;2-E  1
1999 Bartus RT, Chen EY, Lynch G, Kordower JH. Cortical ablation induces a spreading calcium-dependent, secondary pathogenesis which can be reduced by inhibiting calpain. Experimental Neurology. 155: 315-26. PMID 10072307 DOI: 10.1006/exnr.1998.7001  1
1999 Hauser RA, Freeman TB, Snow BJ, Nauert M, Gauger L, Kordower JH, Olanow CW. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease Archives of Neurology. 56: 179-187. PMID 10025423 DOI: 10.1001/archneur.56.2.179  1
1998 Mufson EJ, Kahl U, Bowser R, Mash DC, Kordower JH, Deecher DC. Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential. Annals of the New York Academy of Sciences. 863: 291-304. PMID 9928179 DOI: 10.1111/j.1749-6632.1998.tb10703.x  1
1998 Emborg ME, Ma SY, Mufson EJ, Levey AI, Taylor MD, Brown WD, Holden JE, Kordower JH. Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. The Journal of Comparative Neurology. 401: 253-65. PMID 9822152 DOI: 10.1002/(SICI)1096-9861(19981116)401:2<253::AID-CNE7>3.0.CO;2-X  1
1998 Kordower JH, Freeman TB, Chen EY, Mufson EJ, Sanberg PR, Hauser RA, Snow B, Olanow CW. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 13: 383-93. PMID 9613726 DOI: 10.1002/mds.870130303  1
1998 Kordower JH, Freeman TB, Olanow CW. Neuropathology of fetal nigral crafts in patients with Parkinson's disease Movement Disorders. 13: 88-95. PMID 9613724  1
1998 Emerich DF, Bruhn S, Chu Y, Kordower JH. Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease. Cell Transplantation. 7: 213-25. PMID 9588602 DOI: 10.1016/S0963-6897(97)00163-2  1
1997 Carpenter MK, Winkler C, Fricker R, Emerich DF, Wong SC, Greco C, Chen EY, Chu Y, Kordower JH, Messing A, Björklund A, Hammang JP. Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice. Experimental Neurology. 148: 187-204. PMID 9398461 DOI: 10.1006/exnr.1997.6657  1
1997 Kordower JH, Chen EY, Winkler C, Fricker R, Charles V, Messing A, Mufson EJ, Wong SC, Rosenstein JM, Björklund A, Emerich DF, Hammang J, Carpenter MK. Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease. The Journal of Comparative Neurology. 387: 96-113. PMID 9331174 DOI: 10.1002/(SICI)1096-9861(19971013)387:1<96::AID-CNE8>3.0.CO;2-I  1
1997 Mufson EJ, Sobreviela T, Kordower JH. Chapter VII Chemical neuroanatomy of the primate insula cortex: Relationship to cytoarchitectonics, connectivity, function and neurodegeneration Handbook of Chemical Neuroanatomy. 13: 377-454. DOI: 10.1016/S0924-8196(97)80009-7  1
1995 Hammang JP, Emerich DF, Winn SR, Lee A, Lindner MD, Gentile FT, Doherty EJ, Kordower JH, Baetge EE. DELIVERY OF NEUROTROPHIC FACTORS TO THE CNS USING ENCAPSULATED CELLS: DEVELOPING TREATMENTS FOR NEURODEGENERATIVE DISEASES. Cell Transplantation. 4: 27-28. PMID 28173905  0.48
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