| Year |
Citation |
Score |
| 2024 |
Wong TN, Mychalowych A, Feldpausch ER, Carson A, Karpova D, Link DC. The Clonal Hematopoiesis-associated Gene Plays an Essential Role in Hematopoiesis. Biorxiv : the Preprint Server For Biology. PMID 39229096 DOI: 10.1101/2024.08.16.607812 |
0.686 |
|
| 2024 |
Gruszczynska A, Maiti A, Miller CA, Ramakrishnan SM, Link DC, Uy GL, Petti AA, Hayes K, DiNardo CD, Ravandi F, Ley TJ, Spencer DH, Gao F, Konopleva MY, Welch JS. Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes. Haematologica. PMID 38618679 DOI: 10.3324/haematol.2022.281396 |
0.583 |
|
| 2023 |
Abel HJ, Oetjen KA, Miller CA, Ramakrishnan SM, Day RB, Helton NM, Fronick CC, Fulton RS, Heath SE, Tarnawsky SP, Nonavinkere Srivatsan S, Duncavage EJ, Schroeder MC, Payton JE, Spencer DH, ... ... Link DC, et al. Genomic landscape of TP53-mutated myeloid malignancies. Blood Advances. PMID 37339484 DOI: 10.1182/bloodadvances.2023010156 |
0.632 |
|
| 2023 |
Abel HJ, Oetjen KA, Miller CA, Ramakrishnan SM, Day RB, Helton NM, Fronick CC, Fulton RS, Heath SE, Tarnawsky SP, Srivatsan SN, Duncavage EJ, Schroeder MC, Payton JE, Spencer DH, ... ... Link DC, et al. Genomic landscape of -mutated myeloid malignancies. Medrxiv : the Preprint Server For Health Sciences. PMID 36711871 DOI: 10.1101/2023.01.10.23284322 |
0.622 |
|
| 2022 |
Kramer MH, Zhang Q, Sprung R, Day RB, Erdmann-Gilmore P, Li Y, Xu Z, Helton NM, George DR, Mi Y, Westervelt P, Payton JE, Ramakrishnan SM, Miller CA, Link DC, et al. Proteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia. Blood. PMID 35895896 DOI: 10.1182/blood.2022016033 |
0.64 |
|
| 2022 |
Menssen AJ, Khanna A, Miller CA, Nonavinkere Srivatsan S, Chang GS, Shao J, Robinson J, O'Laughlin M, Fronick CC, Fulton RS, Brendel K, Heath SE, Saba R, Welch JS, Spencer DH, ... ... Link DC, et al. Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression. Blood Cancer Discovery. OF1-OF16. PMID 35709710 DOI: 10.1158/2643-3230.BCD-21-0155 |
0.637 |
|
| 2022 |
Li S, Yao JC, Oetjen KA, Krambs JR, Xia J, Zhang J, Schmidt AP, Helton NM, Fulton RS, Heath SE, Turnbull IR, Mbalaviele G, Ley TJ, Walter MJ, Link DC. IL-1b expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function. Blood. PMID 35675516 DOI: 10.1182/blood.2022016084 |
0.81 |
|
| 2022 |
Yao JC, Oetjen KA, Wang T, Xu H, Abou-Ezzi G, Krambs JR, Uttarwar S, Duncavage EJ, Link DC. TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche. The Journal of Clinical Investigation. PMID 35439167 DOI: 10.1172/JCI154092 |
0.81 |
|
| 2022 |
Upadhyay P, Beales J, Shah NM, Gruszczynska A, Miller CA, Petti AA, Ramakrishnan SM, Link DC, Ley TJ, Welch JS. Recurrent Transcriptional Responses in AML and MDS patients Treated with Decitabine. Experimental Hematology. PMID 35429619 DOI: 10.1016/j.exphem.2022.04.002 |
0.625 |
|
| 2022 |
Ferraro F, Gruszczynska A, Ruzinova MB, Miller CA, Percival ME, Uy GL, Pusic I, Jacoby MA, Christopher MJ, Kim MY, Westervelt P, Cashen AF, Schroeder MA, DiPersio JF, Abboud CN, ... ... Link DC, et al. Decitabine salvage for Tumor Protein P53mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy. Haematologica. PMID 35236053 DOI: 10.3324/haematol.2021.280153 |
0.568 |
|
| 2022 |
Petti AA, Khan SM, Xu Z, Helton N, Fronick CC, Fulton R, Ramakrishnan SM, Nonavinkere Srivatsan S, Heath SE, Westervelt P, Payton JE, Walter MJ, Link DC, DiPersio J, Miller C, et al. Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia. Blood Cancer Discovery. 3: 32-49. PMID 35019859 DOI: 10.1158/2643-3230.BCD-21-0050 |
0.643 |
|
| 2021 |
Wilson ER, Helton NM, Heath SE, Fulton RS, Payton JE, Welch JS, Walter MJ, Westervelt P, DiPersio JF, Link DC, Miller CA, Ley TJ, Spencer DH. Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells. Leukemia. PMID 34873300 DOI: 10.1038/s41375-021-01476-y |
0.627 |
|
| 2021 |
Ferraro F, Miller CA, Christensen KA, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Kohlschmidt J, Eisfeld AK, Bloomfield CD, Ramakrishnan SM, Day RB, Wartman LD, Uy GL, Welch JS, ... ... Link DC, et al. Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34845035 DOI: 10.1073/pnas.2116427118 |
0.819 |
|
| 2021 |
Glaser DE, Curtis MB, Sariano PA, Rollins ZA, Shergill BS, Anand A, Deely AM, Shirure VS, Anderson L, Lowen JM, Ng NR, Weilbaecher K, Link DC, George SC. Organ-on-a-chip model of vascularized human bone marrow niches. Biomaterials. 121245. PMID 34810038 DOI: 10.1016/j.biomaterials.2021.121245 |
0.302 |
|
| 2021 |
Krambs JR, Monlish DA, Gao F, Schuettpelz LG, Link DC. Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice. Frontiers in Immunology. 12: 767267. PMID 34737755 DOI: 10.3389/fimmu.2021.767267 |
0.787 |
|
| 2021 |
Duncavage EJ, Schroeder MC, O'Laughlin M, Wilson R, MacMillan S, Bohannon A, Kruchowski S, Garza J, Du F, Hughes AEO, Robinson J, Hughes E, Heath SE, Baty JD, Neidich J, ... ... Link DC, et al. Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers. The New England Journal of Medicine. 384: 924-935. PMID 33704937 DOI: 10.1056/NEJMoa2024534 |
0.786 |
|
| 2020 |
Shannon K, Link DC. Soil and Seed: Coconspirators in Therapy-Induced Myeloid Neoplasms. Blood Cancer Discovery. 1: 10-12. PMID 34661135 DOI: 10.1158/2643-3249.BCD-20-0080 |
0.313 |
|
| 2020 |
Ritter M, Klimiankou M, Klimenkova O, Schambach A, Hoffmann D, Schmidt A, Kanz L, Link DC, Welte K, Skokowa J. Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs. Annals of Hematology. 99: 2329-2338. PMID 32821971 DOI: 10.1007/S00277-020-04194-0 |
0.486 |
|
| 2020 |
Xiao J, Wang C, Yao JC, Alippe Y, Yang T, Kress D, Sun K, Kostecki KL, Monahan JB, Veis DJ, Abu-Amer Y, Link DC, Mbalaviele G. Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells. Plos Biology. 18: e3000807. PMID 32760056 DOI: 10.1371/Journal.Pbio.3000807 |
0.333 |
|
| 2020 |
Warren JT, Link DC. Clonal hematopoiesis and risk for hematologic malignancy. Blood. PMID 32736382 DOI: 10.1182/Blood.2019000991 |
0.362 |
|
| 2020 |
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Link DC, et al. Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 11: 3856. PMID 32724180 DOI: 10.1038/S41467-020-17555-0 |
0.633 |
|
| 2020 |
Kapoor V, Collins A, Griffith K, Ghosh S, Wong N, Wang X, Challen GA, Krambs J, Link D, Hallahan DE, Thotala D. Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow. Oncotarget. 11: 1681-1690. PMID 32477458 DOI: 10.18632/Oncotarget.27564 |
0.825 |
|
| 2020 |
Krambs JR, Abou Ezzi G, Yao JC, Link DC. Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions. Plos One. 15: e0233751. PMID 32470079 DOI: 10.1371/Journal.Pone.0233751 |
0.814 |
|
| 2020 |
Matsushita Y, Nagata M, Kozloff KM, Welch JD, Mizuhashi K, Tokavanich N, Hallett SA, Link DC, Nagasawa T, Ono W, Ono N. A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nature Communications. 11: 332. PMID 31949165 DOI: 10.1038/S41467-019-14029-W |
0.448 |
|
| 2019 |
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Link DC, et al. Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 10: 5649. PMID 31827082 DOI: 10.1038/S41467-019-13542-2 |
0.69 |
|
| 2019 |
Berrien-Elliott MM, Sun Y, Neal C, Ireland A, Trissal MC, Sullivan RP, Wagner JA, Leong JW, Wong P, Mah-Som AY, Wong TN, Schappe T, Keppel CR, Cortez VS, Stamatiades EG, ... ... Link DC, et al. MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells. Immunity. PMID 31402259 DOI: 10.1016/J.Immuni.2019.06.016 |
0.657 |
|
| 2019 |
Abou-Ezzi G, Supakorndej T, Zhang J, Anthony B, Krambs J, Celik H, Karpova D, Craft CS, Link DC. TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow. Stem Cell Reports. PMID 31204302 DOI: 10.1016/J.Stemcr.2019.05.017 |
0.812 |
|
| 2019 |
Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, Abou-Ezzi G, Celik H, Wiercinska E, Yang W, Gao F, ... ... Link DC, et al. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. The Journal of Clinical Investigation. 130. PMID 31085833 DOI: 10.1172/Jci124738 |
0.387 |
|
| 2019 |
Zhang J, Supakorndej T, Krambs JR, Rao M, Abou-Ezzi G, Ye RY, Li S, Trinkaus K, Link DC. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. The Journal of Clinical Investigation. 130. PMID 31039135 DOI: 10.1172/Jci124829 |
0.822 |
|
| 2019 |
Warren JT, Wattanasirakul P, Spencer DH, Locke A, Makaryan V, Bolyard AA, Welte K, Skokowa J, Dale DC, Link DC. Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia Blood. 134: 433-433. DOI: 10.1182/Blood-2019-129635 |
0.419 |
|
| 2019 |
Yao J, Abou Ezzi G, Krambs JR, Uttarwar S, Duncavage EJ, Link DC. TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms Blood. 134: 470-470. DOI: 10.1182/Blood-2019-128943 |
0.815 |
|
| 2019 |
Xia J, Sun S, Jotte MR, Uy GL, Bohana-Kashtan O, Sorani E, Vainstein A, Peled A, Link DC. CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death Blood. 134: 2745-2745. DOI: 10.1182/Blood-2019-128881 |
0.373 |
|
| 2019 |
Oetjen KA, Bender DE, Ruzinova MB, Oh ST, Link DC. Interrogating the Spatial Architecture of Human Bone Marrow Via Imaging Mass Cytometry Blood. 134: 3728-3728. DOI: 10.1182/Blood-2019-127460 |
0.401 |
|
| 2019 |
Uy GL, Kadia TM, Stock W, Brammer JE, Bohana-Kashtan O, Vainstein A, Sorani E, Chen H, DiPersio JF, Link DC. CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma Blood. 134: 2630-2630. DOI: 10.1182/Blood-2019-127121 |
0.316 |
|
| 2019 |
Dale DC, Shannon JA, Bolyard AA, Connelly J, Link DC, Bonilla MA, Newburger PE. Severe Chronic Neutropenia in the Large Granular Lymphocyte Syndrome: Outcomes in Response to Granulocyte Colony Stimulating Factor (G-CSF) and Immunosuppressive Therapies Blood. 134: 3589-3589. DOI: 10.1182/Blood-2019-126181 |
0.392 |
|
| 2018 |
Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, ... ... Link DC, et al. Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. The New England Journal of Medicine. PMID 30380364 DOI: 10.1056/Nejmoa1808777 |
0.79 |
|
| 2018 |
Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, ... ... Link DC, et al. Mutation Clearance after Transplantation for Myelodysplastic Syndrome. The New England Journal of Medicine. 379: 1028-1041. PMID 30207916 DOI: 10.1056/Nejmoa1804714 |
0.813 |
|
| 2018 |
Trissal MC, Wong TN, Yao JC, Ramaswamy R, Kuo I, Baty JD, Sun Y, Jih G, Parikh N, Berrien-Elliott MM, Fehniger TA, Ley TJ, Maillard I, Reddy P, Link DC. MIR142 loss-of-function mutations derepress ASH1L to increase HOXA gene expression and promote leukemogenesis. Cancer Research. PMID 29724719 DOI: 10.1158/0008-5472.Can-17-3592 |
0.763 |
|
| 2018 |
Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Robinson J, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Pusic I, Welch JS, Link DC, DiPersio JF, et al. Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant. Jci Insight. 3. PMID 29515031 DOI: 10.1172/Jci.Insight.98962 |
0.756 |
|
| 2018 |
Wong TN, Miller CA, Jotte MRM, Bagegni N, Baty JD, Schmidt AP, Cashen AF, Duncavage EJ, Helton NM, Fiala M, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, ... ... Link DC, et al. Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential. Nature Communications. 9: 455. PMID 29386642 DOI: 10.1038/S41467-018-02858-0 |
0.807 |
|
| 2018 |
Warner WA, Spencer DH, Trissal M, White BS, Helton N, Ley TJ, Link DC. Expression profiling of snoRNAs in normal hematopoiesis and AML. Blood Advances. 2: 151-163. PMID 29365324 DOI: 10.1182/Bloodadvances.2017006668 |
0.655 |
|
| 2018 |
Ritter MU, Klimenkova O, Klimiankou M, Schmidt AE, Stocking C, Kanz L, Zeidler C, Link DC, Welte K, Skokowa J. Understanding the Role of CSF3R and Runx1 Runt Homology Domain Missense Mutations in Leukemic Transformation of Hematopoietic Stem Cells Blood. 132: 1101-1101. DOI: 10.1182/Blood-2018-99-118644 |
0.49 |
|
| 2018 |
Abou Ezzi G, Supakorndej T, Zhang J, Krambs JR, Celik H, Link DC. TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches Blood. 132: 3847-3847. DOI: 10.1182/Blood-2018-99-117396 |
0.823 |
|
| 2018 |
Xia J, Jotte MR, Sun S, Uy GL, Vainstein A, Sorani E, Bohana-Kashtan O, Shaw S, Link DC. The CXCR4 Antagonist, BL8040, Is Highly Active Against Human T-ALL in Preclinical Models Blood. 132: 2700-2700. DOI: 10.1182/Blood-2018-99-117213 |
0.36 |
|
| 2018 |
Jacoby M, Bera R, Fletcher T, Fiala MA, Trinkaus K, DiPersio JF, Stockerl-Goldstein KE, Schroeder MA, Link DC, Vij R. A Study of Tbo-Filgrastim (Granix) to Disrupt the Bone Marrow Microenvironment in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation Blood. 132: 2146-2146. DOI: 10.1182/Blood-2018-99-115603 |
0.359 |
|
| 2018 |
Yao J, Abou Ezzi G, Krambs JR, Duncavage EJ, Link DC. TGF-Beta Signaling in Mesenchymal Stromal Cells Contributes to Myelofibrosis but Not Hematopoietic Phenotypes in Myeloproliferative Neoplasms Blood. 132: 3053-3053. DOI: 10.1182/Blood-2018-99-113745 |
0.823 |
|
| 2018 |
Dale DC, Bolyard AA, Alter BP, Bonilla MA, Connelly J, Link DC, Newburger PE, Rosenberg PS, Shimamura A, Walkovich KJ. Myelodysplasia, Leukemia, Lymphoid Malignancies, and Other Cancers in Patients with Severe Chronic Neutropenia Blood. 132: 16-16. DOI: 10.1182/Blood-2018-99-112694 |
0.348 |
|
| 2017 |
Xia J, Miller CA, Baty J, Ramesh A, Jotte MRM, Fulton RS, Vogel TP, Cooper MA, Walkovich KJ, Makaryan V, Bolyard AA, Dinauer MC, Wilson DB, Vlachos A, Myers KC, ... ... Link DC, et al. Somatic mutations and clonal hematopoiesis in congenital neutropenia. Blood. PMID 29092827 DOI: 10.1182/Blood-2017-08-801985 |
0.401 |
|
| 2017 |
Zhang J, Griffith M, Miller CA, Griffith OL, Spencer DH, Walker JR, Magrini V, McGrath SD, Ly A, Helton NM, Trissal M, Link DC, Dang HX, Larson DE, Kulkarni S, et al. Comprehensive discovery of non-coding RNAs in acute myeloid leukemia cell transcriptomes. Experimental Hematology. PMID 28760689 DOI: 10.1016/J.Exphem.2017.07.008 |
0.59 |
|
| 2017 |
Wong TN, Link DC. miR-125b promotes leukemogenesis via VEGFA. Blood. 129: 1409-1410. PMID 28302689 DOI: 10.1182/Blood-2017-01-761544 |
0.621 |
|
| 2017 |
Fontana F, Hickman-Brecks CL, Salazar VS, Revollo L, Abou-Ezzi G, Grimston SK, Jeong SY, Watkins M, Fortunato M, Alippe Y, Link DC, Mbalaviele G, Civitelli R. N-cadherin Regulation of Bone Growth and Homeostasis Is Osteolineage Stage-Specific. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28240364 DOI: 10.1002/Jbmr.3112 |
0.38 |
|
| 2017 |
Spencer DH, Russler-Germain DA, Ketkar S, Helton NM, Lamprecht TL, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Shinawi M, Westervelt P, Payton JE, Wartman LD, Welch JS, Wilson RK, ... ... Link DC, et al. CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression. Cell. PMID 28215704 DOI: 10.1016/J.Cell.2017.01.021 |
0.679 |
|
| 2017 |
Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, ... ... Link DC, et al. Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy. Blood. PMID 28082444 DOI: 10.1182/Blood-2016-10-745273 |
0.677 |
|
| 2017 |
Wong TN, Miller CA, Jotte MR, Bagegni N, Baty JD, Schmidt AE, Cashen AF, Duncavage EJ, Helton NM, Fiala MA, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, ... ... Link DC, et al. Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential Blood. 130: 469-469. DOI: 10.1182/Blood.V130.Suppl_1.469.469 |
0.736 |
|
| 2017 |
Yao J, Wong TN, Trissal M, Ramaswamy R, Sun Y, Reddy PR, Link DC. Abstract 3042:MIR142loss-of-function mutations promote leukemogenesis through derepression ofASH1Lresulting in increasedHOXgene expression Cancer Research. 77: 3042-3042. DOI: 10.1158/1538-7445.Am2017-3042 |
0.661 |
|
| 2016 |
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, ... ... Link DC, et al. TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes. The New England Journal of Medicine. 375: 2023-2036. PMID 27959731 DOI: 10.1056/Nejmoa1605949 |
0.737 |
|
| 2016 |
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reinick T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, ... ... Link DC, et al. Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy. Leukemia. PMID 27740633 DOI: 10.1038/Leu.2016.282 |
0.769 |
|
| 2016 |
Yao JC, Link DC. The Malignant Hematopoietic Stem Cell Niche. Stem Cells (Dayton, Ohio). PMID 27647718 DOI: 10.1002/Stem.2487 |
0.441 |
|
| 2016 |
Walji TA, Turecamo SE, Sanchez AC, Anthony BA, Abou-Ezzi G, Scheller EL, Link DC, Mecham RP, Craft CS. Marrow Adipose Tissue Expansion Coincides with Insulin Resistance in MAGP1-Deficient Mice. Frontiers in Endocrinology. 7: 87. PMID 27445989 DOI: 10.3389/Fendo.2016.00087 |
0.346 |
|
| 2016 |
Zhang J, Link DC. Targeting of Mesenchymal Stromal Cells by Cre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27237054 DOI: 10.1002/Jbmr.2877 |
0.394 |
|
| 2016 |
Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, ... ... Link DC, et al. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology. PMID 27181063 DOI: 10.1016/J.Exphem.2016.04.011 |
0.802 |
|
| 2016 |
Jacoby MA, Duncavage EJ, Chang GS, Miller CA, Shao J, Elliott K, Fulton RS, Fronick C, O'Laughlin M, Link DC, DiPersio JF, Westervelt P, Ley TJ, Graubert TA, Walter MJ, et al. Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant Blood. 128: 5506-5506. DOI: 10.1182/Blood.V128.22.5506.5506 |
0.756 |
|
| 2016 |
Xia J, Shimamura A, Myers KC, Boxer LA, Dale DC, Ramesh A, Jotte M, Link DC. Mutation Burden in Hematopoietic Stem Cells Is Not Increased in Congenital Neutropenia Blood. 128: 405-405. DOI: 10.1182/Blood.V128.22.405.405 |
0.478 |
|
| 2016 |
Zhang J, Link DC, Supakorndej T, Rao M. Myeloid Dendritic Cells Contribute to Hematopoietic Homeostasis Blood. 128: 30-30. DOI: 10.1182/Blood.V128.22.30.30 |
0.692 |
|
| 2016 |
Yao J, Wong TN, Trissal M, Ramaswamy R, Sun Y, Ley TJ, Reddy PR, Link DC. MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression Blood. 128: 2718-2718. DOI: 10.1182/Blood.V128.22.2718.2718 |
0.776 |
|
| 2016 |
Makaryan V, Fletcher B, Kelley ML, Bolyard AA, Link DC, Duncavage EJ, Qualls DA, Dale DC. TCIRG1 Mutations As a Cause for Chronic Neutropenia Blood. 128: 2511-2511. DOI: 10.1182/Blood.V128.22.2511.2511 |
0.32 |
|
| 2016 |
Christopher M, Petti AA, Miller C, Wartman LD, Payton JE, Heath S, Fulton R, Welch JS, Walter MJ, Westervelt P, Link DC, Wilson RK, Ley TJ, DiPersio JF. Clonal Evolution of Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation Blood. 128: 1528-1528. DOI: 10.1182/Blood.V128.22.1528.1528 |
0.828 |
|
| 2016 |
Spencer D, Russler-Germain D, Helton NM, Lamprecht TL, Shinawi M, Westervelt P, Payton JE, Fulton RS, Wilson RK, Walter MJ, Link DC, DiPersio JF, Ley TJ. DNMT3A-Dependent DNA Methylation May Act As a Tumor Suppressor-Not a Tumor Promoter-during AML Progression Blood. 128: 1050-1050. DOI: 10.1182/Blood.V128.22.1050.1050 |
0.696 |
|
| 2015 |
Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, ... ... Link DC, et al. Rapid expansion of pre-existing non-leukemic hematopoietic clones frequently follows induction therapy for de novo AML. Blood. PMID 26631115 DOI: 10.1182/Blood-2015-10-677021 |
0.816 |
|
| 2015 |
Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, ... ... Link DC, et al. Genomic analysis of germline and somatic variants in familial myelodysplasia/acute myeloid leukemia. Blood. PMID 26492932 DOI: 10.1182/Blood-2015-04-641100 |
0.734 |
|
| 2015 |
Calvi LM, Link DC. The hematopoietic stem cell niche in homeostasis and disease. Blood. 126: 2443-51. PMID 26468230 DOI: 10.1182/Blood-2015-07-533588 |
0.4 |
|
| 2015 |
Uy GL, Hsu YS, Schmidt AP, Stock W, Fletcher TR, Trinkaus KM, Westervelt P, DiPersio JF, Link DC. Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia. Leukemia Research. PMID 26467815 DOI: 10.1182/Blood.V122.21.1398.1398 |
0.477 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, ... ... Link DC, et al. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. Jama. 314: 811-22. PMID 26305651 DOI: 10.1001/Jama.2015.9643 |
0.788 |
|
| 2015 |
Day RB, Bhattacharya D, Nagasawa T, Link DC. Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice. Blood. 125: 3114-7. PMID 25814527 DOI: 10.1182/Blood-2015-02-629444 |
0.431 |
|
| 2015 |
Leong JW, Schneider SE, Sullivan RP, Parikh BA, Anthony BA, Singh A, Jewell BA, Schappe T, Wagner JA, Link DC, Yokoyama WM, Fehniger TA. PTEN regulates natural killer cell trafficking in vivo. Proceedings of the National Academy of Sciences of the United States of America. 112: E700-9. PMID 25646418 DOI: 10.1073/Pnas.1413886112 |
0.373 |
|
| 2015 |
Young AL, Wong TN, Hughes AE, Heath SE, Ley TJ, Link DC, Druley TE. Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing. Leukemia. 29: 1608-11. PMID 25644247 DOI: 10.1038/Leu.2015.17 |
0.768 |
|
| 2015 |
Lodhi IJ, Wei X, Yin L, Feng C, Adak S, Abou-Ezzi G, Hsu FF, Link DC, Semenkovich CF. Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability. Cell Metabolism. 21: 51-64. PMID 25565205 DOI: 10.1016/J.Cmet.2014.12.002 |
0.326 |
|
| 2015 |
Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, ... ... Link DC, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/Nature13968 |
0.814 |
|
| 2015 |
Rao M, Supakorndej T, Schmidt AP, Link DC. Osteoclasts are dispensable for hematopoietic progenitor mobilization by granulocyte colony-stimulating factor in mice. Experimental Hematology. 43: 110-4.e1-2. PMID 25461255 DOI: 10.1016/J.Exphem.2014.10.012 |
0.678 |
|
| 2015 |
Makaryan V, Zeidler C, Bolyard AA, Skokowa J, Rodger E, Kelley ML, Boxer LA, Bonilla MA, Newburger PE, Shimamura A, Zhu B, Rosenberg PS, Link DC, Welte K, Dale DC. The diversity of mutations and clinical outcomes for ELANE-associated neutropenia. Current Opinion in Hematology. 22: 3-11. PMID 25427142 DOI: 10.1097/Moh.0000000000000105 |
0.344 |
|
| 2015 |
Welch JS, Petti A, Miller CA, Link DC, Walter MJ, Fronick CC, Fulton RS, Wartman LD, Uy GL, Ghobadi A, Tomasson M, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein K, et al. Dynamic Changes in Clonal Clearance with Decitabine Therapy in AML and MDS Patients Blood. 126: 689-689. DOI: 10.1182/Blood.V126.23.689.689 |
0.666 |
|
| 2015 |
Wong TN, Klco JM, Demeter R, Miller CA, Petti A, Havey N, Fulton R, Heath S, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert T, Wilson RK, ... ... Link DC, et al. Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Cytoreductive Chemotherapy in Adult De Novo AML Patients Blood. 126: 686-686. DOI: 10.1182/Blood.V126.23.686.686 |
0.824 |
|
| 2015 |
Abou Ezzi G, Suparkorndej T, Anthony B, Zhang J, Ganguly S, Civitelli R, Link DC. Loss of TGF-β Signaling in Bone Marrow Mesenchymal Progenitors Promotes Adipocyte over Osteoblast Differentiation but Does Not Disrupt the HSC Niche Blood. 126: 666-666. DOI: 10.1182/Blood.V126.23.666.666 |
0.446 |
|
| 2015 |
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Fulton RS, Fronick CC, O'Laughlin M, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, et al. Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy Blood. 126: 610-610. DOI: 10.1182/blood.v126.23.610.610 |
0.75 |
|
| 2015 |
Warner WA, Spencer D, Trissal M, Helton N, Ley TJ, Link DC. Characterization of snoRNA Expression in Acute Myeloid Leukemia Blood. 126: 3649-3649. DOI: 10.1182/Blood.V126.23.3649.3649 |
0.67 |
|
| 2015 |
Zhang J, Link DC. Targeting Bone Marrow Mesenchymal Stromal Cells Using Cre-Recombinase Transgenes Blood. 126: 2401-2401. DOI: 10.1182/Blood.V126.23.2401.2401 |
0.421 |
|
| 2015 |
Yao J, Wong TN, Trissal M, Sun Y, Ley TJ, Reddy P, Link DC. Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs Blood. 126: 1254-1254. DOI: 10.1182/Blood.V126.23.1254.1254 |
0.774 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, ... ... Link DC, et al. Abstract PR11: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr11 |
0.817 |
|
| 2015 |
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, ... ... Link DC, et al. Abstract PR03: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr03 |
0.817 |
|
| 2015 |
Link DC. Regulation of hematopoiesis by cxcl12/cxcr4 signaling Targeted Therapy of Acute Myeloid Leukemi. 593-605. DOI: 10.1007/978-1-4939-1393-0_30 |
0.365 |
|
| 2014 |
Day RB, Link DC. Megakaryocytes in the hematopoietic stem cell niche. Nature Medicine. 20: 1233-4. PMID 25375920 DOI: 10.1038/Nm.3745 |
0.402 |
|
| 2014 |
Lu EP, McLellan M, Ding L, Fulton R, Mardis ER, Wilson RK, Miller CA, Westervelt P, DiPersio JF, Link DC, Walter MJ, Ley TJ, Graubert TA. Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice. Blood. 124: 3887-95. PMID 25349173 DOI: 10.1182/Blood-2014-06-582551 |
0.747 |
|
| 2014 |
Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC, McMichael JF, Schmidt HK, Yellapantula V, Miller CA, Ozenberger BA, Welch JS, Link DC, Walter MJ, Mardis ER, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nature Medicine. 20: 1472-8. PMID 25326804 DOI: 10.1038/Nm.3733 |
0.675 |
|
| 2014 |
Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, et al. Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing. Plos Genetics. 10: e1004462. PMID 25010716 DOI: 10.1371/Journal.Pgen.1004462 |
0.733 |
|
| 2014 |
Wilson DB, Link DC, Mason PJ, Bessler M. Inherited bone marrow failure syndromes in adolescents and young adults. Annals of Medicine. 46: 353-63. PMID 24888387 DOI: 10.3109/07853890.2014.915579 |
0.347 |
|
| 2014 |
Panni RZ, Sanford DE, Belt BA, Mitchem JB, Worley LA, Goetz BD, Mukherjee P, Wang-Gillam A, Link DC, Denardo DG, Goedegebuure SP, Linehan DC. Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunology, Immunotherapy : Cii. 63: 513-28. PMID 24652403 DOI: 10.1007/S00262-014-1527-X |
0.349 |
|
| 2014 |
Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell. 25: 379-92. PMID 24613412 DOI: 10.1016/J.Ccr.2014.01.031 |
0.743 |
|
| 2014 |
Schuettpelz LG, Borgerding JN, Christopher MJ, Gopalan PK, Romine MP, Herman AC, Woloszynek JR, Greenbaum AM, Link DC. G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling. Leukemia. 28: 1851-60. PMID 24518205 DOI: 10.1038/Leu.2014.68 |
0.81 |
|
| 2014 |
Anthony BA, Link DC. Regulation of hematopoietic stem cells by bone marrow stromal cells. Trends in Immunology. 35: 32-7. PMID 24210164 DOI: 10.1016/J.It.2013.10.002 |
0.428 |
|
| 2014 |
Calvi LM, Link DC. Cellular complexity of the bone marrow hematopoietic stem cell niche. Calcified Tissue International. 94: 112-24. PMID 24101231 DOI: 10.1007/S00223-013-9805-8 |
0.428 |
|
| 2014 |
Xia J, Link DC, Uy GL. G-CSF Augments Inotuzamab-Mediated Clearance of Acute Lymphoblastic Leukemia from the Bone Marrow Blood. 124: 5502-5502. DOI: 10.1182/Blood.V124.21.5502.5502 |
0.449 |
|
| 2014 |
Young A, Wong TN, Ley TJ, Link DC, Druley TE. Rare Hematopoietic Subclones Harboring Leukemogenic TP53 Mutations Are Detectable Via Error-Corrected Sequencing in Healthy Elderly Individuals Blood. 124: 2907-2907. DOI: 10.1182/Blood.V124.21.2907.2907 |
0.784 |
|
| 2014 |
Dale DC, Bolyard AA, Zeidler C, Marrero TM, Boxer LA, Newburger PE, Alter BP, Morrow P, Bonilla MA, Dror Y, Firkin F, Kinsey S, Levine JE, Link DC, Reeves L, et al. Understanding Neutropenia: The 20 Year Experience of the Severe Chronic Neutropenia International Registry (SCNIR) Blood. 124: 2730-2730. DOI: 10.1182/Blood.V124.21.2730.2730 |
0.391 |
|
| 2014 |
Klimenkova O, Klimiankou M, Schmidt A, Stocking C, Zeidler C, Link DC, Welte K, Skokowa J. Co-Acquisition of RUNX1 and CSF3R Mutations Transforms Hematopoietic Progenitor Cells of CN Patients into More Primitive Highly Proliferative Blasts: Evidence in CN Patients and in a Mouse Model Blood. 124: 223-223. DOI: 10.1182/Blood.V124.21.223.223 |
0.474 |
|
| 2013 |
Ramsingh G, Jacoby MA, Shao J, De Jesus Pizzaro RE, Shen D, Trissal M, Getz AH, Ley TJ, Walter MJ, Link DC. Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon. Blood. 122: e44-51. PMID 24009227 DOI: 10.1182/Blood-2013-03-488007 |
0.616 |
|
| 2013 |
Schuettpelz LG, Link DC. Regulation of hematopoietic stem cell activity by inflammation. Frontiers in Immunology. 4: 204. PMID 23882270 DOI: 10.3389/Fimmu.2013.00204 |
0.45 |
|
| 2013 |
Link DC. SNAREing a new cause of neutropenia. Blood. 121: 4969-70. PMID 23788021 DOI: 10.1182/Blood-2013-05-498717 |
0.371 |
|
| 2013 |
Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, ... Link DC, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia. 27: 1275-82. PMID 23443460 DOI: 10.1038/Leu.2013.58 |
0.741 |
|
| 2013 |
Greenbaum A, Hsu YM, Day RB, Schuettpelz LG, Christopher MJ, Borgerding JN, Nagasawa T, Link DC. CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature. 495: 227-30. PMID 23434756 DOI: 10.1038/Nature11926 |
0.821 |
|
| 2013 |
Link DC. Osteocytes link bone maintenance to blood homeostasis. Blood. 121: 867-8. PMID 23393015 DOI: 10.1182/Blood-2012-12-468637 |
0.383 |
|
| 2013 |
Link D. Mechanisms of Neutrophil Release from the Bone Marrow Blood. 122: SCI-43-SCI-43. DOI: 10.1182/Blood.V122.21.Sci-43.Sci-43 |
0.472 |
|
| 2013 |
Supakorndej T, Rao M, Link DC. Myeloid Dendritic Cells Regulate HSPC Trafficking In The Bone Marrow Blood. 122: 584-584. DOI: 10.1182/Blood.V122.21.584.584 |
0.709 |
|
| 2013 |
Neal Wong T, Ramsingh G, Young A, Shen D, Miller C, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch J, Walter MJ, Graubert T, DiPersio JF, ... ... Link DC, et al. The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML Blood. 122: 5-5. DOI: 10.1182/Blood.V122.21.5.5 |
0.749 |
|
| 2013 |
Trissal M, Silva J, Wylie T, Hundal J, McGrath S, Magrini V, Ramsingh G, Mardis ER, Ley TJ, Link DC. Dysregulation and Recurrent Mutation Of miRNA-142 In De Novo AML Blood. 122: 472-472. DOI: 10.1182/Blood.V122.21.472.472 |
0.626 |
|
| 2013 |
Schuettpelz LG, Borgerding JN, Gopalan P, Christopher M, Romine M, Woloszynek J, Greenbaum A, Link DC. G-CSF Treatment Induces Toll-Like Receptor Signaling and Regulates Hematopoietic Stem Cell Function Blood. 122: 1181-1181. DOI: 10.1182/Blood.V122.21.1181.1181 |
0.82 |
|
| 2012 |
Hsu YM, Link DC. Enhancing hematopoietic growth factor performance. Nature Medicine. 18: 1740-1. PMID 23223059 DOI: 10.1038/Nm.3022 |
0.309 |
|
| 2012 |
Link DC. Molecular genetics of AML. Best Practice & Research. Clinical Haematology. 25: 409-14. PMID 23200536 DOI: 10.1016/J.Beha.2012.10.002 |
0.381 |
|
| 2012 |
Schuettpelz LG, Gopalan PK, Giuste FO, Romine MP, van Os R, Link DC. Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. Blood. 120: 2981-9. PMID 22936656 DOI: 10.1182/Blood-2012-02-409839 |
0.416 |
|
| 2012 |
Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/J.Cell.2012.06.023 |
0.755 |
|
| 2012 |
Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, ... ... Link DC, et al. Clonal architecture of secondary acute myeloid leukemia. The New England Journal of Medicine. 366: 1090-8. PMID 22417201 DOI: 10.1056/Nejmoa1106968 |
0.767 |
|
| 2012 |
Greenbaum AM, Revollo LD, Woloszynek JR, Civitelli R, Link DC. N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood. 120: 295-302. PMID 22323481 DOI: 10.1182/Blood-2011-09-377457 |
0.707 |
|
| 2012 |
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, ... ... Link DC, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/Nature10738 |
0.797 |
|
| 2012 |
Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, ... ... Link DC, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/Ng.1031 |
0.749 |
|
| 2012 |
Day RB, Link DC. Regulation of neutrophil trafficking from the bone marrow. Cellular and Molecular Life Sciences : Cmls. 69: 1415-23. PMID 22045556 DOI: 10.1007/S00018-011-0870-8 |
0.397 |
|
| 2012 |
Xia J, Boxer LA, Link DC. ER Stress-Induced Expression of CCAAT/Enhancer Binding Protein Gamma (C/EBPG) May Contribute to the Block in Granulocytic Differentiation in Severe Congenital Neutropenia Blood. 120: 8-8. DOI: 10.1182/Blood.V120.21.8.8 |
0.427 |
|
| 2012 |
Ramsingh G, Shen D, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch JS, Walter MJ, Graubert T, DiPersio JF, Ley TJ, Wilson RK, Link DC. Whole Genome Sequencing of Therapy-Related Acute Myeloid Leukemia Blood. 120: 784-784. DOI: 10.1182/Blood.V120.21.784.784 |
0.755 |
|
| 2012 |
Hsu YS, Greenbaum A, Schuettpelz LG, Christopher M, Borgerding JN, Day RB, Nagasawa T, Link DC. CXCL12 Production by Early Mesenchymal Progenitors Is Required for Hematopoietic Stem Cell Maintenance Blood. 120: 510-510. DOI: 10.1182/Blood.V120.21.510.510 |
0.822 |
|
| 2012 |
Trissal M, Spencer DH, Silva J, Wylie T, Hundal J, McGrath S, Magrini V, Ramsingh G, Wilson RJ, Ley TJ, Link DC. Dysregulation of the Imprinted DLK1-DIO3 Locus in Promyelocytic Leukemia Blood. 120: 3500-3500. DOI: 10.1182/Blood.V120.21.3500.3500 |
0.648 |
|
| 2012 |
Supakorndej T, Rao M, Link D. Myeloid Dendritic Cells Contribute to Hematopoietic Progenitor Mobilization by G-CSF. Blood. 120: 2319-2319. DOI: 10.1182/Blood.V120.21.2319.2319 |
0.698 |
|
| 2012 |
Dale DC, Bolyard AA, Marrero TM, Bonilla MA, Link DC, Newburger PE, Shimamura A, Boxer LA, Repository. The Natural History of Cyclic Neutropenia: Long-Term Prospective Observations and Current Perspectives. Blood. 120: 2141-2141. DOI: 10.1182/Blood.V120.21.2141.2141 |
0.362 |
|
| 2012 |
Borgerding JN, Gopalan P, Christopher M, Link DC, Schuettpelz LG. G-CSF Treatment Induces Hematopoietic Stem Cell Quiescence but Loss of Repopulating Activity Blood. 120: 1206-1206. DOI: 10.1182/Blood.V120.21.1206.1206 |
0.808 |
|
| 2011 |
Yoda M, Kimura T, Tohmonda T, Uchikawa S, Koba T, Takito J, Morioka H, Matsumoto M, Link DC, Chiba K, Okada Y, Toyama Y, Horiuchi K. Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis. Blood. 118: 6939-42. PMID 22042698 DOI: 10.1182/Blood-2011-06-357210 |
0.437 |
|
| 2011 |
Kunter G, Woloszynek JR, Link DC. A truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice. Experimental Hematology. 39: 1136-43. PMID 21911095 DOI: 10.1016/J.Exphem.2011.08.013 |
0.434 |
|
| 2011 |
Greenbaum A, Link DC. CXCR2 is the Tpo of the iceberg. Blood. 117: 4166-7. PMID 21511963 DOI: 10.1182/Blood-2011-02-332577 |
0.7 |
|
| 2011 |
Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, ... ... Link DC, et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. Jama. 305: 1577-84. PMID 21505136 DOI: 10.1001/Jama.2011.497 |
0.718 |
|
| 2011 |
Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/Jama.2011.473 |
0.734 |
|
| 2011 |
Schuettpelz LG, Link DC. Niche competition and cancer metastasis to bone. The Journal of Clinical Investigation. 121: 1253-5. PMID 21436576 DOI: 10.1172/Jci57229 |
0.348 |
|
| 2011 |
Nanua S, Murakami M, Xia J, Grenda DS, Woloszynek J, Strand M, Link DC. Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane. Blood. 117: 3539-47. PMID 21285438 DOI: 10.1182/Blood-2010-10-311704 |
0.793 |
|
| 2011 |
Christopher MJ, Rao M, Liu F, Woloszynek JR, Link DC. Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. The Journal of Experimental Medicine. 208: 251-60. PMID 21282380 DOI: 10.1084/Jem.20101700 |
0.832 |
|
| 2011 |
Greenbaum AM, Link DC. Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization. Leukemia. 25: 211-7. PMID 21079612 DOI: 10.1038/Leu.2010.248 |
0.708 |
|
| 2011 |
Welch JS, Larson D, Ding L, McLellan MD, Lamprecht T, Kandoth C, Payton JE, Baty J, Harris CC, Lichti CF, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, ... ... Link DC, et al. Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes Blood. 118: 404-404. DOI: 10.1182/Blood.V118.21.404.404 |
0.746 |
|
| 2011 |
Dale DC, Makaryan V, Bolyard AA, Rodger ER, Kelley ML, Marrero TM, Phan L, Aprikyan AA, Bonilla MA, Newburger PE, Boxer LA, Link D. ELANE Mutations in Cyclic and Congenital Neutropenia: Genotype-Phenotype Relationships, Blood. 118: 3398-3398. DOI: 10.1182/Blood.V118.21.3398.3398 |
0.373 |
|
| 2011 |
Day RB, Greenbaum A, Rao M, Link D. G-CSF Induces Alterations in the Bone Marrow Microenvironment That Suppress B Lymphopoiesis, Blood. 118: 3243-3243. DOI: 10.1182/Blood.V118.21.3243.3243 |
0.795 |
|
| 2011 |
Schuettpelz L, Giuste F, Gopalan P, Link D. Kruppel Like Factor 7 Suppresses Hematopoietic Stem and Progenitor Cell Function Blood. 118: 2356-2356. DOI: 10.1182/Blood.V118.21.2356.2356 |
0.445 |
|
| 2011 |
Olsson HA, Plassard A, Dexheimer P, Phelan JD, Melnick A, Xia J, Link DC, Opferman J, Aronow BJ, Grimes HL. Conserved Transcriptional Deregulation Underlies GFI1 and ELANE Mutant Neutropenia Blood. 118: 13-13. DOI: 10.1182/Blood.V118.21.13.13 |
0.455 |
|
| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Link DC, et al. DNMT3A mutations in acute myeloid leukemia. The New England Journal of Medicine. 363: 2424-33. PMID 21067377 DOI: 10.1056/Nejmoa1005143 |
0.741 |
|
| 2010 |
Fehniger TA, Wylie T, Germino E, Leong JW, Magrini VJ, Koul S, Keppel CR, Schneider SE, Koboldt DC, Sullivan RP, Heinz ME, Crosby SD, Nagarajan R, Ramsingh G, Link DC, et al. Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Research. 20: 1590-604. PMID 20935160 DOI: 10.1101/Gr.107995.110 |
0.614 |
|
| 2010 |
Link D. Stem cells on the move Nature Medicine. 16: 1073-1074. PMID 20930742 DOI: 10.1038/Nm1010-1073 |
0.374 |
|
| 2010 |
Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang LW, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, ... Link DC, et al. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood. 116: 5316-26. PMID 20876853 DOI: 10.1182/Blood-2010-05-285395 |
0.633 |
|
| 2010 |
Eash KJ, Greenbaum AM, Gopalan PK, Link DC. CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. The Journal of Clinical Investigation. 120: 2423-31. PMID 20516641 DOI: 10.1172/Jci41649 |
0.823 |
|
| 2010 |
Rosová I, Link D, Nolta JA. shRNA-mediated decreases in c-Met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair. Tissue Engineering. Part A. 16: 2627-39. PMID 20367286 DOI: 10.1089/Ten.Tea.2009.0363 |
0.793 |
|
| 2010 |
Gregory AD, Capoccia BJ, Woloszynek JR, Link DC. Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes. Journal of Leukocyte Biology. 88: 123-31. PMID 20354107 DOI: 10.1189/Jlb.0709499 |
0.809 |
|
| 2010 |
Ramsingh G, Koboldt D, Magrini V, Trissal M, Koul S, Chang L, Nagarajan R, Ley TJ, Mardis E, Link DC. Characterization of the microRNAome in a patient with acute myeloid leukemia. Journal of Clinical Oncology. 28: 10501-10501. DOI: 10.1200/Jco.2010.28.15_Suppl.10501 |
0.625 |
|
| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch JS, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Link DC, et al. Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes Blood. 116: 99-99. DOI: 10.1182/Blood.V116.21.99.99 |
0.75 |
|
| 2010 |
Schuettpelz L, Link DC, Shen D, Walter MJ, Koboldt DC, Dooling DJ, Fulton RS, Schmidt H, Maupin R, O'Laughlin M, Chen K, McLellan MD, Kulkarni S, Ivanovich J, Lebeau M, et al. DNA Sequence of the Cancer Genome of a Patient with Therapy-Related Acute Myeloid Leukemia Blood. 116: 580-580. DOI: 10.1182/Blood.V116.21.580.580 |
0.754 |
|
| 2010 |
Kunter GM, Woloszynek J, Link DC. Alterations In the Bone Marrow Microenvironment Contribute to Oxidative Stress and DNA Damage In Hematopoietic Stem/Progenitors Carrying a Csf3r Truncation Mutation Blood. 116: 387-387. DOI: 10.1182/Blood.V116.21.387.387 |
0.438 |
|
| 2010 |
Dale DC, Makaryan V, Bolyard AA, Elin R, Aprikyan AA, Bonilla MA, Newburger PE, Boxer LA, Link D. Neutrophil Elastase Mutations and the Risk of Leukemia In Patients with Cyclic and Congenital Neutropenia. Blood. 116: 3786-3786. DOI: 10.1182/Blood.V116.21.3786.3786 |
0.407 |
|
| 2010 |
Ramsingh G, Matson A, Walter MJ, Link DC. High-Resolution Comparative Genomic Hybridization of Mirna Genes In Therapy-Related AML Identifies a Somatic Deletion of MiR-223 Blood. 116: 2759-2759. DOI: 10.1182/Blood.V116.21.2759.2759 |
0.308 |
|
| 2010 |
DiMeglio LA, Bolyard AA, Marrero TM, Alter BP, Bonilla MA, Boxer LA, Link D, Newburger PE, Rosenberg PS, Shimamura A, Dale DC. The Risk of Low Bone Mineral Density with Long-Term G-CSF Therapy for Severe Chronic Neutropenia. Blood. 116: 1484-1484. DOI: 10.1182/Blood.V116.21.1484.1484 |
0.33 |
|
| 2010 |
Fehniger TA, Wylie T, Germino E, Leong JW, Magrini VJ, Koul S, Keppel CR, Schneider SE, Koboldt DC, Sullivan RP, Heinz ME, Crosby SD, Nagarajan R, Ramsingh G, Link DC, et al. The NK Cell MicroRNA Transcriptome Defined by Next-Generation Sequencing Identifies IL-15-Signaled Alterations In Mature MiR-223 Expression, and MiR-223 as a Potential Regulator of Murine Granzyme B Blood. 116: 104-104. DOI: 10.1182/Blood.V116.21.104.104 |
0.608 |
|
| 2010 |
Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang L, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, ... Link DC, et al. Abstract B12: Complete characterization of the “microRNAome” of a human acute myeloid leukemia Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-B12 |
0.623 |
|
| 2009 |
Xia J, Bolyard AA, Rodger E, Stein S, Aprikyan AA, Dale DC, Link DC. Prevalence of mutations in ELANE, GFI1, HAX1, SBDS, WAS and G6PC3 in patients with severe congenital neutropenia. British Journal of Haematology. 147: 535-42. PMID 19775295 DOI: 10.1111/J.1365-2141.2009.07888.X |
0.38 |
|
| 2009 |
Shaked Y, Tang T, Woloszynek J, Daenen LG, Man S, Xu P, Cai SR, Arbeit JM, Voest EE, Chaplin DJ, Smythe J, Harris A, Nathan P, Judson I, Rustin G, ... ... Link DC, et al. Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Research. 69: 7524-8. PMID 19738066 DOI: 10.1158/0008-5472.Can-09-0381 |
0.366 |
|
| 2009 |
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, ... ... Link DC, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. The New England Journal of Medicine. 361: 1058-66. PMID 19657110 DOI: 10.1056/Nejmoa0903840 |
0.747 |
|
| 2009 |
Walter MJ, Payton JE, Ries RE, Shannon WD, Deshmukh H, Zhao Y, Baty J, Heath S, Westervelt P, Watson MA, Tomasson MH, Nagarajan R, O'Gara BP, Bloomfield CD, Mrózek K, ... ... Link DC, et al. Acquired copy number alterations in adult acute myeloid leukemia genomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 12950-5. PMID 19651600 DOI: 10.1073/Pnas.0903091106 |
0.718 |
|
| 2009 |
Payton JE, Grieselhuber NR, Chang LW, Murakami M, Geiss GK, Link DC, Nagarajan R, Watson MA, Ley TJ. High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples. The Journal of Clinical Investigation. 119: 1714-26. PMID 19451695 DOI: 10.1172/Jci38248 |
0.781 |
|
| 2009 |
Capoccia BJ, Robson DL, Levac KD, Maxwell DJ, Hohm SA, Neelamkavil MJ, Bell GI, Xenocostas A, Link DC, Piwnica-Worms D, Nolta JA, Hess DA. Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood. 113: 5340-51. PMID 19324906 DOI: 10.1182/Blood-2008-04-154567 |
0.753 |
|
| 2009 |
Eash KJ, Means JM, White DW, Link DC. CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions. Blood. 113: 4711-9. PMID 19264920 DOI: 10.1182/Blood-2008-09-177287 |
0.816 |
|
| 2009 |
Christopher MJ, Liu F, Hilton MJ, Long F, Link DC. Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. Blood. 114: 1331-9. PMID 19141863 DOI: 10.1182/Blood-2008-10-184754 |
0.81 |
|
| 2009 |
Rao M, Christopher M, Woloszynek J, Liu F, Link DC. Expression of the G-CSF Receptor in Monocytes Is Sufficient to Mediate Osteoblast Suppression and HSPC Mobilization by G-CSF in Mice. Blood. 114: 563-563. DOI: 10.1182/Blood.V114.22.563.563 |
0.822 |
|
| 2009 |
Nanua S, Xia J, Murakami M, Woloszynek J, Link DC. Loss of PERK Signaling Results in Impaired Granulopoiesis in Transgenic Mice Expressing Mutant Ela2. Blood. 114: 551-551. DOI: 10.1182/Blood.V114.22.551.551 |
0.421 |
|
| 2009 |
Kunter GM, Woloszynek J, Ley T, Link DC. Increased ROS Stress and Alterations in the Bone Marrow Microenvironment Contribute to DNA Damage in Hematopoietic Stem/Progenitors Carrying a Csf3r Truncation Mutation. Blood. 114: 3630-3630. DOI: 10.1182/Blood.V114.22.3630.3630 |
0.697 |
|
| 2009 |
Zeidler C, Donadieu J, Bolyard AA, Vandenberghe P, Pracht G, Beaupain B, Hoy L, Zimmermann M, Bellanne-Chantelot C, Link DC, Klein C, Germeshausen M, Dale DC, Welte K. Update On the Risk of Leukemia in Genetic Subgroups of Congenital Neutropenia (CN): Comparison of Patients with Known Gene Mutations (ELA2, HAX1, WASP, G6PC3, p14). Blood. 114: 3597-3597. DOI: 10.1182/Blood.V114.22.3597.3597 |
0.385 |
|
| 2009 |
Ramsingh G, Koboldt DC, Fehniger TA, Wylie T, Magrini V, Trissal M, Koul S, Chang L, Nagarajan R, Ley TJ, Mardis E, Link DC. Comprehensive Evaluation of MicroRNA Genes and Gene Expression Using Next Generation Sequencing in a Patient with Acute Myelogenous Leukemia. Blood. 114: 271-271. DOI: 10.1182/Blood.V114.22.271.271 |
0.634 |
|
| 2009 |
Eash KJ, Greenbaum AM, Gopalan P, Diaz GA, Link DC. CXCR2 Signals Act in Concert with CXCR4 to Regulate Neutrophil Release From the Bone Marrow. Blood. 114: 235-235. DOI: 10.1182/Blood.V114.22.235.235 |
0.827 |
|
| 2008 |
Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, ... ... Link DC, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 456: 66-72. PMID 18987736 DOI: 10.1038/Nature07485 |
0.749 |
|
| 2008 |
Christopher MJ, Link DC. Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1765-74. PMID 18597629 DOI: 10.1359/Jbmr.080612 |
0.795 |
|
| 2008 |
Hunter MG, McLemore M, Link DC, Loveland M, Copelan A, Avalos BR. Divergent pathways in COS-7 cells mediate defective internalization and intracellular routing of truncated G-CSFR forms in SCN/AML. Plos One. 3: e2452. PMID 18560579 DOI: 10.1371/Journal.Pone.0002452 |
0.362 |
|
| 2008 |
Capoccia BJ, Gregory AD, Link DC. Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. Journal of Leukocyte Biology. 84: 760-8. PMID 18550788 DOI: 10.1189/Jlb.1107756 |
0.806 |
|
| 2008 |
Rosová I, Dao M, Capoccia B, Link D, Nolta JA. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells (Dayton, Ohio). 26: 2173-82. PMID 18511601 DOI: 10.1634/Stemcells.2007-1104 |
0.798 |
|
| 2008 |
Devine SM, Vij R, Rettig M, Todt L, McGlauchlen K, Fisher N, Devine H, Link DC, Calandra G, Bridger G, Westervelt P, Dipersio JF. Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction. Blood. 112: 990-8. PMID 18426988 DOI: 10.1182/Blood-2007-12-130179 |
0.356 |
|
| 2008 |
Zhou P, Hohm S, Capoccia B, Wirthlin L, Hess D, Link D, Nolta J. Immunodeficient mouse models to study human stem cell-mediated tissue repair. Methods in Molecular Biology (Clifton, N.J.). 430: 213-25. PMID 18370302 DOI: 10.1007/978-1-59745-182-6_15 |
0.352 |
|
| 2008 |
Liu F, Kunter G, Krem MM, Eades WC, Cain JA, Tomasson MH, Hennighausen L, Link DC. Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5. The Journal of Clinical Investigation. 118: 946-55. PMID 18292815 DOI: 10.1172/Jci32704 |
0.455 |
|
| 2008 |
Tomasson MH, Xiang Z, Walgren R, Zhao Y, Kasai Y, Miner T, Ries RE, Lubman O, Fremont DH, McLellan MD, Payton JE, Westervelt P, DiPersio JF, Link DC, Walter MJ, et al. Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood. 111: 4797-808. PMID 18270328 DOI: 10.1182/Blood-2007-09-113027 |
0.759 |
|
| 2008 |
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner TL, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, et al. Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood. 111: 4809-12. PMID 18160671 DOI: 10.1182/Blood-2007-05-090308 |
0.766 |
|
| 2008 |
Xia J, Link DC. Severe congenital neutropenia and the unfolded protein response. Current Opinion in Hematology. 15: 1-7. PMID 18043239 DOI: 10.1097/Moh.0B013E3282F13Cd2 |
0.303 |
|
| 2008 |
Rosenberg PS, Alter BP, Link DC, Stein S, Rodger E, Bolyard AA, Aprikyan AA, Bonilla MA, Dror Y, Kannourakis G, Newburger PE, Boxer LA, Dale DC. Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. British Journal of Haematology. 140: 210-3. PMID 18028488 DOI: 10.1111/J.1365-2141.2007.06897.X |
0.398 |
|
| 2008 |
Gregory AD, Capoccia BJ, Link DC. Conditioning of Monocytes in the Bone Marrow by Inflammatory Cytokines Inhibits Their Angiogenic Potential at Peripheral Sites of Ischemia Blood. 112: 471-471. DOI: 10.1182/Blood.V112.11.471.471 |
0.797 |
|
| 2008 |
Xia J, Bolyard AA, Rodger E, Stein S, Aprikyan AA, Dale DC, Link DC. Incidence of SCN-Assoicated Gene Mutations in Severe Congenital Neutropenia Patients in North America Blood. 112: 3553-3553. DOI: 10.1182/Blood.V112.11.3553.3553 |
0.373 |
|
| 2008 |
Christopher M, Link DC. Bone Marrow Monocyte/Macrophages Provide Signals Necessary for Osteoblast Maintenance: Potential Role for Insulin-Like Growth Factor Signaling Blood. 112: 323-323. DOI: 10.1182/Blood.V112.11.323.323 |
0.811 |
|
| 2008 |
Murakami M, Woloszynek J, Xia J, Liu F, Link D. Induction of the Unfolded Protein Response but Normal Basal Granulopoiesis in Mice Expressing G192X ELA2 Blood. 112: 314-314. DOI: 10.1182/Blood.V112.11.314.314 |
0.423 |
|
| 2008 |
Gopalan PK, Christopher MJ, Greenbaum AM, Link DC. Disruption of the Osteoblast Niche by G-CSF Is Associated with Hematopoietic Stem Cell Quiescence and Loss of Long-Term Repopulating Activity: Role of Cdkn1a Blood. 112: 2447-2447. DOI: 10.1182/Blood.V112.11.2447.2447 |
0.827 |
|
| 2007 |
Grenda DS, Murakami M, Ghatak J, Xia J, Boxer LA, Dale D, Dinauer MC, Link DC. Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood. 110: 4179-87. PMID 17761833 DOI: 10.1182/Blood-2006-11-057299 |
0.802 |
|
| 2007 |
Rawls AS, Gregory AD, Woloszynek JR, Liu F, Link DC. Lentiviral-mediated RNAi inhibition of Sbds in murine hematopoietic progenitors impairs their hematopoietic potential. Blood. 110: 2414-22. PMID 17638857 DOI: 10.1182/Blood-2006-03-007112 |
0.757 |
|
| 2007 |
Link DC, Kunter G, Kasai Y, Zhao Y, Miner T, McLellan MD, Ries RE, Kapur D, Nagarajan R, Dale DC, Bolyard AA, Boxer LA, Welte K, Zeidler C, Donadieu J, et al. Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood. 110: 1648-55. PMID 17494858 DOI: 10.1182/Blood-2007-03-081216 |
0.76 |
|
| 2007 |
Gregory AD, Hogue LA, Ferkol TW, Link DC. Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection. Blood. 109: 3235-43. PMID 17185469 DOI: 10.1182/Blood-2005-01-015081 |
0.716 |
|
| 2007 |
Christopher MJ, Link DC. Regulation of neutrophil homeostasis. Current Opinion in Hematology. 14: 3-8. PMID 17133093 DOI: 10.1097/00062752-200701000-00003 |
0.784 |
|
| 2007 |
Yuan W, Payton JE, Holt MS, Link DC, Watson MA, DiPersio JF, Ley TJ. Commonly dysregulated genes in murine APL cells. Blood. 109: 961-70. PMID 17008535 DOI: 10.1182/Blood-2006-07-036640 |
0.664 |
|
| 2007 |
Xiang Z, Zhao Y, Mitaksov V, Fremont DH, Kasai Y, Molitoris A, Ries RE, Miner T, McLellan MD, DiPersio JF, Link DC, Payton JE, Graubert TA, Watson M, Shannon W, et al. Identification of Novel, Non-Synonymous Sequence Changes in the Tyrosine Kinase Genes of Patients with Acute Myeloid Leukemia. Blood. 110: 823-823. DOI: 10.1182/Blood.V110.11.823.823 |
0.761 |
|
| 2007 |
Payton JE, Grieselhuber NR, Chang L, Murakami MA, Yuan W, Link DC, Nagarajan R, Watson MA, Ley TJ. The Expression Signature of M3 AML Suggests Direct and Indirect Effects of PML-RARA on Target Genes. Blood. 110: 719-719. DOI: 10.1182/Blood.V110.11.719.719 |
0.788 |
|
| 2007 |
Murakami M, Xia J, Jordan CT, Boxer LA, Dale D, Bolyard AA, Dinauer MC, Link DC. Granulocytic Precursors from Patients with ELA2-Mutant Severe Congenital Neutropenia Display a Transcriptional Profile Consistent with Activation of the Unfolded Protein Response. Blood. 110: 662-662. DOI: 10.1182/Blood.V110.11.662.662 |
0.407 |
|
| 2007 |
Levac KD, Robson DL, Neelamkavil MJ, Hohm SA, Capoccia BJ, Link DC, Nolta JA, Hess DA. Aldehyde Dehydrogenase-Activity Purifies Multiple Hemangiogenic Lineages That Accelerate Vascularization of Ischemic Tissue through Paracrine Support of Neovessel Formation. Blood. 110: 3716-3716. DOI: 10.1182/Blood.V110.11.3716.3716 |
0.754 |
|
| 2007 |
Boxer LA, Bolyard AA, Newburger PE, Bonilla MA, Kannourakis G, Dror Y, Link DC, Alter BP, Rosenberg PS, Dale DC. Predictors of Transformation to Myelodysplasia/Acute Myelogenous Leukemia (MDS/AML) in Severe Congenital Neutropenia (SCN). Blood. 110: 3307-3307. DOI: 10.1182/Blood.V110.11.3307.3307 |
0.433 |
|
| 2007 |
Dale DC, Bolyard AA, Newburger PE, Bonilla MA, Kannourakis G, Dror Y, Link DC, Alter BP, Rosenberg PS, Boxer LA. Cyclic Neutropenia Is Not Associated with Transformation to MDS and AML. Blood. 110: 3306-3306. DOI: 10.1182/Blood.V110.11.3306.3306 |
0.369 |
|
| 2007 |
Eash KJ, Means JM, Woloszynek JR, Liu F, Link DC. CXCR4 Signals Regulate Neutrophil Release from the Bone Marrow but Not Clearance from the Circulation. Blood. 110: 3297-3297. DOI: 10.1182/Blood.V110.11.3297.3297 |
0.826 |
|
| 2007 |
Gregory AD, Capoccia BJ, Link DC. The Inflammatory Subset of Monocytes Stimulates Angiogenesis at Sites of Ischemia by Altering the Balance of Pro- and Anti-Inflammatory Cytokines. Blood. 110: 240-240. DOI: 10.1182/Blood.V110.11.240.240 |
0.795 |
|
| 2007 |
Gopalan PK, Christopher MJ, Link DC. Disruption of the Osteoblast Niche by G-CSF Induces Hematopoietic Stem Cell Quiescence and Loss of Long-Term Repopulating Activity. Blood. 110: 2217-2217. DOI: 10.1182/Blood.V110.11.2217.2217 |
0.807 |
|
| 2007 |
Woloszynek JR, Kunter GM, Ley T, Link DC. G-CSFSR Mutations Present in Patients with Severe Congenital Neutropenia Cooperate with PML-RARα To Induce Acute Myeloid Leukemia in Mice. Blood. 110: 2193-2193. DOI: 10.1182/Blood.V110.11.2193.2193 |
0.447 |
|
| 2007 |
Ley TJ, DiPersio J, Ding L, Ries R, Magrini V, Payton J, McGrath S, Walter M, Wylie T, Dunford-Shore B, Chen K, McLellan M, Wendl M, Dooling D, Cook L, ... ... Link D, et al. Sequencing an Acute Myeloid Leukemia (AML) Genome with “Next Generation” Technologies. Blood. 110: 205-205. DOI: 10.1182/Blood.V110.11.205.205 |
0.745 |
|
| 2007 |
Walter MJ, Ries R, Li X, Shannon W, Payton J, Books J, Bloomfield C, Mrozek K, Ruppert A, DiPersio J, Link D, Tomasson M, Graubert T, Westervelt P, Watson M, et al. High Resolution Array-Based CGH and SNP Studies of AML Genomes. Blood. 110: 107-107. DOI: 10.1182/Blood.V110.11.107.107 |
0.722 |
|
| 2006 |
Güven H, Shepherd RM, Bach RG, Capoccia BJ, Link DC. The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. Journal of the American College of Cardiology. 48: 1579-87. PMID 17045891 DOI: 10.1016/J.Jacc.2006.04.101 |
0.705 |
|
| 2006 |
Shepherd RM, Capoccia BJ, Devine SM, Dipersio J, Trinkaus KM, Ingram D, Link DC. Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100. Blood. 108: 3662-7. PMID 16912220 DOI: 10.1182/Blood-2006-06-030577 |
0.732 |
|
| 2006 |
Nervi B, Link DC, DiPersio JF. Cytokines and hematopoietic stem cell mobilization Journal of Cellular Biochemistry. 99: 690-705. PMID 16888804 DOI: 10.1002/Jcb.21043 |
0.407 |
|
| 2006 |
Panopoulos AD, Zhang L, Snow JW, Jones DM, Smith AM, El Kasmi KC, Liu F, Goldsmith MA, Link DC, Murray PJ, Watowich SS. STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood. 108: 3682-90. PMID 16888100 DOI: 10.1182/Blood-2006-02-003012 |
0.434 |
|
| 2006 |
Grenda DS, Link DC. 5. Mechanisms of disordered granulopoiesis in congenital neutropenia. Current Topics in Developmental Biology. 74: 133-76. PMID 16860667 DOI: 10.1016/S0070-2153(06)74005-4 |
0.768 |
|
| 2006 |
Mermel CH, McLemore ML, Liu F, Pereira S, Woloszynek J, Lowell CA, Link DC. Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis. Blood. 108: 2562-8. PMID 16772601 DOI: 10.1182/Blood-2006-05-024307 |
0.365 |
|
| 2006 |
Capoccia BJ, Shepherd RM, Link DC. G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood. 108: 2438-45. PMID 16735597 DOI: 10.1182/Blood-2006-04-013755 |
0.736 |
|
| 2006 |
Khanna-Gupta A, Sun H, Zibello T, Lozovatsky L, Ghosh PK, Link DC, McLemore ML, Berliner N. p120 nucleolar-proliferating antigen is a direct target of G-CSF signaling during myeloid differentiation. Journal of Leukocyte Biology. 79: 1011-21. PMID 16641140 DOI: 10.1189/Jlb.0205066 |
0.431 |
|
| 2006 |
Gamero AM, Potla R, Wegrzyn J, Szelag M, Edling AE, Shimoda K, Link DC, Dulak J, Baker DP, Tanabe Y, Grayson JM, Larner AC. Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. The Journal of Biological Chemistry. 281: 16238-44. PMID 16601124 DOI: 10.1074/Jbc.M509516200 |
0.353 |
|
| 2006 |
Christopher MJ, Gopalan PK, Link DC. G-CSF Disrupts the Stem Cell Niche by Increasing Turnover of Bone Marrow Osteoblasts. Blood. 108: 87-87. DOI: 10.1182/Blood.V108.11.87.87 |
0.798 |
|
| 2006 |
Eash KJ, Link DC. CXCR4 Signals Regulate Basal and G-CSF Induced Neutrophil Release from the Bone Marrow. Blood. 108: 673-673. DOI: 10.1182/Blood.V108.11.673.673 |
0.83 |
|
| 2006 |
Kunter GM, Liu F, Krem M, Link D. G-CSF Receptor Mutations Found in Patients with Severe Congenital Neutropenia Confer a Strong Competitive Growth Advantage at the Hematopoietic Stem Cell Level That Is Mediated by STAT5 Activation. Blood. 108: 632-632. DOI: 10.1182/Blood.V108.11.632.632 |
0.417 |
|
| 2006 |
Devine SM, Vij R, Todt L, McLaughlin K, Fisher N, Morris N, Link DC, Calandra G, Bridger G, DiPersio JF. HLA-Matched Sibling Donor Stem Cell Mobilization Can Be Safely and Effectively Reduced from a Five Day to a One Day Process by a Direct Antagonist of the CXCR4/SDF-1 Interaction. Blood. 108: 53-53. DOI: 10.1182/Blood.V108.11.53.53 |
0.348 |
|
| 2006 |
Capoccia BJ, Link DC. The Differential Role of Stromal Derived Factor-1 (SDF-1) and Monocyte Chemoattractant Protein-1 (MCP-1) in the Recruitment of Angiogenic Cells to Ischemic Tissue. Blood. 108: 417-417. DOI: 10.1182/Blood.V108.11.417.417 |
0.768 |
|
| 2006 |
Yuan W, Payton JE, Holt MS, Link DC, Watson MA, DiPersio JF, James Ley T. Commonly Dysregulated Genes in Murine Acute Promyelocytic Leukemia (APL) Cells. Blood. 108: 1925-1925. DOI: 10.1182/Blood.V108.11.1925.1925 |
0.397 |
|
| 2006 |
Sheehan AM, Ford LE, Link DC, Zutter MM. The α2β1 Integrin Regulates Hematopoietic Stem Cell Engraftment. Blood. 108: 1328-1328. DOI: 10.1182/Blood.V108.11.1328.1328 |
0.426 |
|
| 2006 |
Devine S, Todt L, Bonde J, Hess D, Devine H, Nolta J, Link D, Calandra G, Bridger G, DiPersio J. A pilot study evaluating the safety and efficacy of AMD3100 for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells in patients with advanced hematological malignancies Biology of Blood and Marrow Transplantation. 12: 35. DOI: 10.1182/Blood.V104.11.3341.3341 |
0.337 |
|
| 2005 |
Link DC. Neutrophil homeostasis: a new role for stromal cell-derived factor-1. Immunologic Research. 32: 169-78. PMID 16106067 DOI: 10.1385/Ir:32:1-3:169 |
0.41 |
|
| 2005 |
Grenda D, Link DC. A comparison of cyclic neutropenia in childhood and severe congenital neutropenia. Haematologica. 90: 1010A. PMID 16079089 |
0.751 |
|
| 2005 |
Semerad CL, Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I, Levesque JP, Chappel J, Ross FP, Link DC. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood. 106: 3020-7. PMID 16037394 DOI: 10.1182/Blood-2004-01-0272 |
0.827 |
|
| 2005 |
Grenda DS, Link DC. Neutrophil differentiation. Haematologica. 90: 2. PMID 15644299 |
0.763 |
|
| 2005 |
Grenda DS, Link DC. Mutations in the ELA2 Gene Encoding Neutrophil Elastase Induce the Unfolded Protein Response and May Contribute to Neutropenia through the UPR-Dependent Apoptosis of Granulocytic Precursors. Blood. 106: 91-91. DOI: 10.1182/Blood.V106.11.91.91 |
0.818 |
|
| 2005 |
Rawls AS, Woloszynek JR, Link DC. Lentiviral-Mediated RNAi Knockdown of SBDS in Murine Hematopoietic Progenitors Impairs Their Engraftment Potential and Granulocytic Differentiation. Blood. 106: 635-635. DOI: 10.1182/Blood.V106.11.635.635 |
0.429 |
|
| 2005 |
Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I, Levesque J, Link DC. G-CSF Potently Suppresses Osteoblast Activity in the Bone Marrow. Blood. 106: 591-591. DOI: 10.1182/Blood.V106.11.591.591 |
0.81 |
|
| 2005 |
Rettig M, Holt M, Liu F, Ritchey J, Link D, Bridger G, DiPersio J. Evaluation of the Phenotype and GVHD-Inducing Potential of Splenic T Cells Isolated from G-CSF, AMD3100, or G-CSF and AMD3100 Pretreated Allogeneic Donors. Blood. 106: 5224-5224. DOI: 10.1182/Blood.V106.11.5224.5224 |
0.361 |
|
| 2005 |
Shepherd RM, Capoccia BJ, Devine SM, Ingram DA, Link DC. AMD3100 and G-CSF Mobilize Angiogenic Cells into the Blood of Healthy Donors. Blood. 106: 3022-3022. DOI: 10.1182/blood.v106.11.3022.3022 |
0.73 |
|
| 2005 |
Capoccia BJ, Wirthlin L, Shepherd R, O’Dell K, Nolta JA, Link DC, Hess DA. Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury. Blood. 106: 2663-2663. DOI: 10.1182/Blood.V106.11.2663.2663 |
0.735 |
|
| 2005 |
Walter MJ, Ries RR, Li XD, Shannon WJ, Payton J, Bloomfield CD, Mrozek K, Ruppert AS, DiPersio J, Link D, Tomasson M, Graubert T, McLeod H, Devine S, Watson M, et al. Detection of Microdeletions and Amplifications in Primary Human Acute Myeloid Leukemia (AML) Genomes Using Ultradense Oligomer Tiling Path Arrays and Comparative Genomic Hybridization (CGH). Blood. 106: 2350-2350. DOI: 10.1182/Blood.V106.11.2350.2350 |
0.719 |
|
| 2004 |
Han B, Unsinger J, Liu F, Link DC, Bessler M. G-CSF induced progenitor mobilization in mice with PIGA - Blood cells Hematology Journal. 5: 347-352. PMID 15297852 DOI: 10.1038/Sj.Thj.6200383 |
0.48 |
|
| 2004 |
Woloszynek JR, Rothbaum RJ, Rawls AS, Minx PJ, Wilson RK, Mason PJ, Bessler M, Link DC. Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndrome. Blood. 104: 3588-90. PMID 15284109 DOI: 10.1182/Blood-2004-04-1516 |
0.384 |
|
| 2004 |
Levesque JP, Liu F, Simmons PJ, Betsuyaku T, Senior RM, Pham C, Link DC. Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood. 104: 65-72. PMID 15010367 DOI: 10.1182/Blood-2003-05-1589 |
0.427 |
|
| 2004 |
Zhang Y, Woodward VK, Shelton JM, Richardson JA, Zhou XJ, Link D, Kielar ML, Jeyarajah DR, Lu CY. Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro. American Journal of Physiology-Renal Physiology. 286. PMID 14734360 DOI: 10.1152/Ajprenal.00379.2002 |
0.362 |
|
| 2004 |
Grenda DS, Liu F, Richards M, Link DC. G-CSF Receptor Mutations Found in Patients with Severe Congenital Neutropenia Confer a Strong Competitive Advantage at the Hematopoeitic Stem Cell Level That Is Dependent on Increased Systemic Levels of G-CSF. Blood. 104: 457-457. DOI: 10.1182/Blood.V104.11.457.457 |
0.832 |
|
| 2004 |
Christopher MJ, Liu F, Everly N, Link DC. Disruption of SDF-1/CXCR4 Signaling during Flt-3 Ligand and Stem Cell Factor (SCF) Induced Hematopoietic Progenitor Mobilization. Blood. 104: 4139-4139. DOI: 10.1182/Blood.V104.11.4139.4139 |
0.787 |
|
| 2004 |
Capoccia BJ, Shepherd RM, Guven H, Devine SM, Link DC. A Comparison of the Ability of AMD3100 Versus G-CSF to Induce Angiogenesis and Mobilize Endothelial Progenitor Cells (EPCs). Blood. 104: 3597-3597. DOI: 10.1182/Blood.V104.11.3597.3597 |
0.741 |
|
| 2004 |
Devine SM, Link D, DiPersio JF. Novel strategies for hematopoietic stem cell mobilization Current Opinion in Organ Transplantation. 9: 54-63. DOI: 10.1097/00075200-200403000-00012 |
0.333 |
|
| 2003 |
Cottler-Fox MH, Lapidot T, Petit I, Kollet O, DiPersio JF, Link D, Devine S. Stem cell mobilization. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 419-37. PMID 14633793 DOI: 10.1182/Asheducation-2003.1.419 |
0.392 |
|
| 2003 |
Ley TJ, Minx PJ, Walter MJ, Ries RE, Sun H, McLellan M, DiPersio JF, Link DC, Tomasson MH, Graubert TA, McLeod H, Khoury H, Watson M, Shannon W, Trinkaus K, et al. A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14275-80. PMID 14614138 DOI: 10.1073/Pnas.2335924100 |
0.756 |
|
| 2003 |
Watters JW, Kloss EF, Link DC, Graubert TA, McLeod HL. A mouse-based strategy for cyclophosphamide pharmacogenomic discovery. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1352-60. PMID 12970373 DOI: 10.1152/Japplphysiol.00214.2003 |
0.581 |
|
| 2003 |
Richards MK, Liu F, Iwasaki H, Akashi K, Link DC. Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway. Blood. 102: 3562-8. PMID 12893769 DOI: 10.1182/Blood-2003-02-0593 |
0.408 |
|
| 2002 |
Semerad CL, Liu F, Gregory AD, Stumpf K, Link DC. G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity. 17: 413-23. PMID 12387736 DOI: 10.1016/S1074-7613(02)00424-7 |
0.822 |
|
| 2002 |
Grenda DS, Johnson SE, Mayer JR, McLemore ML, Benson KF, Horwitz M, Link DC. Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis. Blood. 100: 3221-8. PMID 12384420 DOI: 10.1182/Blood-2002-05-1372 |
0.833 |
|
| 2002 |
Thomas J, Liu F, Link DC. Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor. Current Opinion in Hematology. 9: 183-9. PMID 11953662 DOI: 10.1097/00062752-200205000-00002 |
0.438 |
|
| 2001 |
McLemore ML, Grewal S, Liu F, Archambault A, Poursine-Laurent J, Haug J, Link DC. STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation Immunity. 14: 193-204. PMID 11239451 DOI: 10.1016/S1074-7613(01)00101-7 |
0.417 |
|
| 2001 |
Link DC. Regulation of granulopoiesis: lessons from leukocyte adhesion deficiency Blood. 98: 3178-3178. DOI: 10.1182/Blood.V98.12.3178 |
0.34 |
|
| 2000 |
Liu F, Poursine-Laurent J, Link DC. Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF Blood. 95: 3025-3031. PMID 10807765 DOI: 10.1182/Blood.V95.10.3025.010K32_3025_3031 |
0.447 |
|
| 2000 |
Link DC. Mechanisms of granulocyte colony-stimulating factor induced hematopoietic progenitor-cell mobilization Seminars in Hematology. 37: 25-32. PMID 10718156 DOI: 10.1016/S0037-1963(00)90086-6 |
0.369 |
|
| 1999 |
Semerad CL, Poursine-Laurent J, Liu F, Link DC. A role for G-CSF receptor signaling in the regulation of hematopoietic cell function but not lineage commitment or differentiation. Immunity. 11: 153-61. PMID 10485650 DOI: 10.1016/S1074-7613(00)80090-4 |
0.799 |
|
| 1999 |
Betsuyaku T, Liu F, Senior RM, Haug JS, Brown EJ, Jones SL, Matsushima K, Link DC. A functional granulocyte colony-stimulating factor receptor is required for normal chemoattractant-induced neutrophil activation. The Journal of Clinical Investigation. 103: 825-32. PMID 10079103 DOI: 10.1172/Jci5191 |
0.332 |
|
| 1998 |
Zhang P, Iwama A, Datta MW, Darlington GJ, Link DC, Tenen DG. Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein α (C/EBPα) is critical for granulopoiesis Journal of Experimental Medicine. 188: 1173-1184. PMID 9743535 DOI: 10.1084/Jem.188.6.1173 |
0.312 |
|
| 1998 |
McLemore ML, Poursine-Laurent J, Link DC. Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony- stimulating factor receptor mutation derived from a patient with severe congenital neutropenia Journal of Clinical Investigation. 102: 483-492. PMID 9691084 DOI: 10.1172/Jci3216 |
0.449 |
|
| 1998 |
Jacob J, Haug JS, Raptis S, Link DC. Specific signals generated by the cytoplasmic domain of the granulocyte colony-stimulating factor (G-CSF) receptor are not required for G-CSF- dependent granulocytic differentiation Blood. 92: 353-361. PMID 9657731 DOI: 10.1182/Blood.V92.2.353.414K37_353_361 |
0.374 |
|
| 1997 |
Liu F, Poursine-Laurent J, Wu HY, Link DC. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation Blood. 90: 2583-2590. PMID 9326224 DOI: 10.1182/Blood.V90.7.2583.2583_2583_2590 |
0.348 |
|
| 1997 |
Liu F, Poursine-Laurent J, Link DC. The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not Flt-3 ligand Blood. 90: 2522-2528. PMID 9326216 DOI: 10.1182/Blood.V90.7.2522.2522_2522_2528 |
0.421 |
|
| 1996 |
Liu F, Wu HY, Wesselschmidt R, Kornaga T, Link DC. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice Immunity. 5: 491-501. PMID 8934575 DOI: 10.1016/S1074-7613(00)80504-X |
0.413 |
|
| 1996 |
Rodel JE, Link DC. Suppression of apoptosis during cytokine deprivation of 32D cells is not sufficient to induce complete granulocytic differentiation Blood. 87: 858-864. PMID 8562953 DOI: 10.1182/Blood.V87.3.858.Bloodjournal873858 |
0.394 |
|
| 1995 |
Link DC, Zutter M. The proto-oncogene c-fgr is expressed in normal mantle zone B lymphocytes and is developmentally regulated during myelomonocytic differentiation in vivo Blood. 85: 472-479. PMID 7812001 DOI: 10.1182/Blood.V85.2.472.Bloodjournal852472 |
0.317 |
|
| 1992 |
Link DC, Gutkind SJ, Robbins KC, Ley TJ. Characterization of the 5' untranslated region of the human c-fgr gene and identification of the major myelomonocytic c-fgr promoter Oncogene. 7: 877-884. PMID 1373875 |
0.58 |
|
| 1991 |
Gutkind JS, Link DC, Katamine S, Lacal P, Miki T, Ley TJ, Robbins KC. A novel c-fgr exon utilized in Epstein-Barr virus-infected B lymphocytes but not in normal monocytes Molecular and Cellular Biology. 11: 1500-1507. PMID 1847500 DOI: 10.1128/Mcb.11.3.1500 |
0.637 |
|
| 1991 |
Perkins SL, Link DC, Kling S, Ley TJ, Teitelbaum SL. 1,25-Dihydroxyvitamin D3 induces monocytic differentiation of the PLB-985 leukemic line and promotes c-fgr mRNA expression Journal of Leukocyte Biology. 50: 427-433. PMID 1660912 DOI: 10.1002/Jlb.50.5.427 |
0.641 |
|
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