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David McKinzie, Ph.D. - Publications

Affiliations: 
Neuroscience Eli Lilly, Indianapolis, IN, United States 
Area:
addiction
Website:
http://www.iupui.edu/~medneuro/FacultyPages/mckinzie.htm

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Monn JA, Prieto L, Taboada L, Hao J, Reinhard MR, Henry SS, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, ... ... McKinzie DL, et al. Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-Substituted-2-Aminobicyclo[3.1.0]hexane-2,6-Dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. Journal of Medicinal Chemistry. PMID 26313429 DOI: 10.1021/acs.jmedchem.5b01124  1
2015 Liu B, Croy CH, Hitchcock SA, Allen JR, Rao Z, Evans D, Bures MG, McKinzie DL, Watt ML, Stuart Gregory G, Hansen MM, Hoogestraat PJ, Jamison JA, Okha-Mokube FM, Stratford RE, et al. Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists. Bioorganic & Medicinal Chemistry Letters. PMID 26299349 DOI: 10.1016/j.bmcl.2015.08.011  1
2015 Kinon BJ, Millen BA, Zhang L, McKinzie DL. Exploratory Analysis for a Targeted Patient Population Responsive to the Metabotropic Glutamate 2/3 Receptor Agonist Pomaglumetad Methionil in Schizophrenia. Biological Psychiatry. PMID 25890643 DOI: 10.1016/j.biopsych.2015.03.016  1
2015 Monn JA, Prieto L, Taboada L, Pedregal C, Hao J, Reinhard MR, Henry SS, Goldsmith PJ, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, ... ... McKinzie DL, et al. Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures. Journal of Medicinal Chemistry. 58: 1776-94. PMID 25602126 DOI: 10.1021/jm501612y  1
2014 Rorick-Kehn LM, Witcher JW, Lowe SL, Gonzales CR, Weller MA, Bell RL, Hart JC, Need AB, McKinzie JH, Statnick MA, Suico JG, McKinzie DL, Tauscher-Wisniewski S, Mitch CH, Stoltz RR, et al. Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25637376 DOI: 10.1093/ijnp/pyu036  1
2014 Toledo MA, Pedregal C, Lafuente C, Diaz N, Martinez-Grau MA, Jiménez A, Benito A, Torrado A, Mateos C, Joshi EM, Kahl SD, Rash KS, Mudra DR, Barth VN, Shaw DB, ... McKinzie D, et al. Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold. Journal of Medicinal Chemistry. 57: 3418-29. PMID 24678969 DOI: 10.1021/jm500117r  1
2014 Rorick-Kehn LM, Witkin JM, Statnick MA, Eberle EL, McKinzie JH, Kahl SD, Forster BM, Wong CJ, Li X, Crile RS, Shaw DB, Sahr AE, Adams BL, Quimby SJ, Diaz N, ... ... McKinzie DL, et al. LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders. Neuropharmacology. 77: 131-44. PMID 24071566 DOI: 10.1016/j.neuropharm.2013.09.021  1
2013 Watt ML, Rorick-Kehn L, Shaw DB, Knitowski KM, Quets AT, Chesterfield AK, McKinzie DL, Felder CC. The muscarinic acetylcholine receptor agonist BuTAC mediates antipsychotic-like effects via the M4 subtype. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2717-26. PMID 23907402 DOI: 10.1038/npp.2013.186  1
2013 Monn JA, Valli MJ, Massey SM, Hao J, Reinhard MR, Bures MG, Heinz BA, Wang X, Carter JH, Getman BG, Stephenson GA, Herin M, Catlow JT, Swanson S, Johnson BG, ... McKinzie DL, et al. Synthesis and pharmacological characterization of 4-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: identification of new potent and selective metabotropic glutamate 2/3 receptor agonists. Journal of Medicinal Chemistry. 56: 4442-55. PMID 23675965 DOI: 10.1021/jm4000165  1
2013 Hao J, Dehlinger V, Fivush AM, Rudyk HC, Britton TC, Hollinshead SP, Vokits BP, Clark BP, Henry SS, Massey SM, Peng L, Dressman BA, Heinz BA, Roberts EF, Bracey-Walker MR, ... ... McKinzie DL, et al. Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator. Bioorganic & Medicinal Chemistry Letters. 23: 1249-52. PMID 23374867 DOI: 10.1016/j.bmcl.2013.01.009  1
2013 Schwarz AJ, Plawecki MH, McKinzie DL, Wong CJ. Translational Neuroimaging. Substance Abuse Disorders Translational Neuroimaging. 307-341. DOI: 10.1016/B978-0-12-386945-6.00011-1  1
2012 McKinzie DL, Bymaster FP. Muscarinic mechanisms in psychotic disorders. Handbook of Experimental Pharmacology. 233-65. PMID 23027418 DOI: 10.1007/978-3-642-25758-2_9  1
2012 Deehan GA, McKinzie DL, Carroll FI, McBride WJ, Rodd ZA. The long-lasting effects of JDTic, a kappa opioid receptor antagonist, on the expression of ethanol-seeking behavior and the relapse drinking of female alcohol-preferring (P) rats. Pharmacology, Biochemistry, and Behavior. 101: 581-7. PMID 22429993 DOI: 10.1016/j.pbb.2012.03.006  1
2012 Tan XJ, Dai YB, Wu WF, Kim HJ, Barros RP, Richardson TI, Yaden BC, Warner M, McKinzie DL, Krishnan V, Gustafsson JÃ…. Reduction of dendritic spines and elevation of GABAergic signaling in the brains of mice treated with an estrogen receptor β ligand. Proceedings of the National Academy of Sciences of the United States of America. 109: 1708-12. PMID 22307635 DOI: 10.1073/pnas.1121162109  1
2012 Dhaher R, Toalston JE, Hauser SR, Bell RL, McKinzie DL, McBride WJ, Rodd ZA. Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats. Alcohol (Fayetteville, N.Y.). 46: 17-27. PMID 21962974 DOI: 10.1016/j.alcohol.2011.08.011  1
2012 Lowe S, Dean R, Ackermann B, Jackson K, Natanegara F, Anderson S, Eckstein J, Yuen E, Ayan-Oshodi M, Ho M, McKinzie D, Perry K, Svensson K. Effects of a novel mGluâ‚‚/₃ receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid. Psychopharmacology. 219: 959-70. PMID 21847569 DOI: 10.1007/s00213-011-2427-9  1
2012 Fell MJ, McKinzie DL, Monn JA, Svensson KA. Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia. Neuropharmacology. 62: 1473-83. PMID 21704048 DOI: 10.1016/j.neuropharm.2011.06.007  1
2012 Marek GJ, Kinon BJ, McKinzie DL, Schkeryantz JM, Monn JA. Metabotropic Glutamate 2/3 Receptor Agonists and Positive Allosteric Modulators of Metabotropic Glutamate Receptor 2 as Novel Agents for the Treatment of Schizophrenia Targets and Emerging Therapies For Schizophrenia. 143-185. DOI: 10.1002/9781118309421.ch6  1
2012 Felder CC, McKinzie DL, Thompson RC, Liu B. Muscarinic Acetylcholine Receptors as Novel Targets for the Development of Therapeutics for Schizophrenia Targets and Emerging Therapies For Schizophrenia. 355-379. DOI: 10.1002/9781118309421.ch13  1
2011 Mitch CH, Quimby SJ, Diaz N, Pedregal C, de la Torre MG, Jimenez A, Shi Q, Canada EJ, Kahl SD, Statnick MA, McKinzie DL, Benesh DR, Rash KS, Barth VN. Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer. Journal of Medicinal Chemistry. 54: 8000-12. PMID 21958337 DOI: 10.1021/jm200789r  1
2011 Watt ML, Schober DA, Hitchcock S, Liu B, Chesterfield AK, McKinzie D, Felder CC. Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist. The Journal of Pharmacology and Experimental Therapeutics. 338: 622-32. PMID 21558436 DOI: 10.1124/jpet.111.182063  1
2010 Dhaher R, Hauser SR, Getachew B, Bell RL, McBride WJ, McKinzie DL, Rodd ZA. The Orexin-1 Receptor Antagonist SB-334867 Reduces Alcohol Relapse Drinking, but not Alcohol-Seeking, in Alcohol-Preferring (P) Rats. Journal of Addiction Medicine. 4: 153-9. PMID 20871792 DOI: 10.1097/ADM.0b013e3181bd893f  1
2010 Arnt J, Bang-Andersen B, Grayson B, Bymaster FP, Cohen MP, DeLapp NW, Giethlen B, Kreilgaard M, McKinzie DL, Neill JC, Nelson DL, Nielsen SM, Poulsen MN, Schaus JM, Witten LM. Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1021-33. PMID 20569520 DOI: 10.1017/S1461145710000659  1
2010 Leach K, Loiacono RE, Felder CC, McKinzie DL, Mogg A, Shaw DB, Sexton PM, Christopoulos A. Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 855-69. PMID 19940843 DOI: 10.1038/npp.2009.194  1
2009 Ciccocioppo R, Gehlert DR, Ryabinin A, Kaur S, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, et al. Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol (Fayetteville, N.Y.). 43: 491-8. PMID 19913192 DOI: 10.1016/j.alcohol.2009.08.003  1
2009 Fell MJ, Perry KW, Falcone JF, Johnson BG, Barth VN, Rash KS, Lucaites VL, Threlkeld PG, Monn JA, McKinzie DL, Marek GJ, Svensson KA, Nelson DL. In vitro and in vivo evidence for a lack of interaction with dopamine D2 receptors by the metabotropic glutamate 2/3 receptor agonists 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-bicaroxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic acid (LY379268). The Journal of Pharmacology and Experimental Therapeutics. 331: 1126-36. PMID 19755662 DOI: 10.1124/jpet.109.160598  1
2009 Shekhar A, McKinzie DL, Felder CC. Drs. Shekhar, McKinzie, and Felder reply American Journal of Psychiatry. 166: 113. DOI: 10.1176/appi.ajp.2008.08091352r1  1
2008 Bell RL, Rodd ZA, Toalston JE, McKinzie DL, Lumeng L, Li TK, McBride WJ, Murphy JM. Autonomic activation associated with ethanol self-administration in adult female P rats. Pharmacology, Biochemistry, and Behavior. 91: 223-32. PMID 18713644 DOI: 10.1016/j.pbb.2008.07.016  1
2008 Chan WY, McKinzie DL, Bose S, Mitchell SN, Witkin JM, Thompson RC, Christopoulos A, Lazareno S, Birdsall NJ, Bymaster FP, Felder CC. Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 105: 10978-83. PMID 18678919 DOI: 10.1073/pnas.0800567105  1
2008 Shekhar A, Potter WZ, Lightfoot J, Lienemann J, Dubé S, Mallinckrodt C, Bymaster FP, McKinzie DL, Felder CC. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. The American Journal of Psychiatry. 165: 1033-9. PMID 18593778 DOI: 10.1176/appi.ajp.2008.06091591  1
2008 Little HJ, McKinzie DL, Setnik B, Shram MJ, Sellers EM. Pharmacotherapy of alcohol dependence: Improving translation from the bench to the clinic Animal and Translational Models For Cns Drug Discovery. 3: 91-178. DOI: 10.1016/B978-0-12-373861-5.00025-4  1
2007 Shannon HE, Eberle EL, Mitch CH, McKinzie DL, Statnick MA. Effects of kappa opioid receptor agonists on attention as assessed by a 5-choice serial reaction time task in rats. Neuropharmacology. 53: 930-41. PMID 17959202 DOI: 10.1016/j.neuropharm.2007.09.002  1
2007 Rorick-Kehn LM, Johnson BG, Knitowski KM, Salhoff CR, Witkin JM, Perry KW, Griffey KI, Tizzano JP, Monn JA, McKinzie DL, Schoepp DD. In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders. Psychopharmacology. 193: 121-36. PMID 17384937 DOI: 10.1007/s00213-007-0758-3  1
2007 Gehlert DR, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Ciccocioppo R, Heilig M. 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2718-26. PMID 17344409 DOI: 10.1523/JNEUROSCI.4985-06.2007  1
2007 Rorick-Kehn LM, Johnson BG, Burkey JL, Wright RA, Calligaro DO, Marek GJ, Nisenbaum ES, Catlow JT, Kingston AE, Giera DD, Herin MF, Monn JA, McKinzie DL, Schoepp DD. Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic acid (LY404039). The Journal of Pharmacology and Experimental Therapeutics. 321: 308-17. PMID 17204749 DOI: 10.1124/jpet.106.110809  1
2006 Rodd ZA, McKinzie DL, Bell RL, McQueen VK, Murphy JM, Schoepp DD, McBride WJ. The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats. Behavioural Brain Research. 171: 207-15. PMID 16678921 DOI: 10.1016/j.bbr.2006.03.032  1
2006 Tzavara ET, Bymaster FP, Overshiner CD, Davis RJ, Perry KW, Wolff M, McKinzie DL, Witkin JM, Nomikos GG. Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine. Molecular Psychiatry. 11: 187-95. PMID 16231039 DOI: 10.1038/sj.mp.4001763  1
2006 Rorick-Kehn LM, Perkins EJ, Knitowski KM, Hart JC, Johnson BG, Schoepp DD, McKinzie DL. Improved bioavailability of the mGlu2/3 receptor agonist LY354740 using a prodrug strategy: in vivo pharmacology of LY544344. The Journal of Pharmacology and Experimental Therapeutics. 316: 905-13. PMID 16223873 DOI: 10.1124/jpet.105.091926  1
2006 Smith DG, Davis RJ, Rorick-Kehn L, Morin M, Witkin JM, McKinzie DL, Nomikos GG, Gehlert DR. Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stress responses in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1135-45. PMID 16205780 DOI: 10.1038/sj.npp.1300913  1
2005 Rorick-Kehn LM, Hart JC, McKinzie DL. Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands. Psychopharmacology. 183: 226-40. PMID 16175401 DOI: 10.1007/s00213-005-0169-2  1
2005 Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s). Psychopharmacology. 179: 271-83. PMID 15717213 DOI: 10.1007/s00213-004-2099-9  1
2005 Jones CK, Eberle EL, Shaw DB, McKinzie DL, Shannon HE. Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats. The Journal of Pharmacology and Experimental Therapeutics. 312: 1055-63. PMID 15574685 DOI: 10.1124/jpet.104.075887  1
2004 Tzavara ET, Bymaster FP, Davis RJ, Wade MR, Perry KW, Wess J, McKinzie DL, Felder C, Nomikos GG. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1410-2. PMID 15231726 DOI: 10.1096/fj.04-1575fje  1
2004 Rodd ZA, Bell RL, McKinzie DL, Webster AA, Murphy JM, Lumeng L, Li TK, McBride WJ. Low-dose stimulatory effects of ethanol during adolescence in rat lines selectively bred for high alcohol intake. Alcoholism, Clinical and Experimental Research. 28: 535-43. PMID 15100603 DOI: 10.1097/01.ALC.0000122107.08417.D0  1
2003 Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL. Muscarinic mechanisms of antipsychotic atypicality. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 1125-43. PMID 14642972 DOI: 10.1016/j.pnpbp.2003.09.008  1
2003 Svenningsson P, Tzavara ET, Carruthers R, Rachleff I, Wattler S, Nehls M, McKinzie DL, Fienberg AA, Nomikos GG, Greengard P. Diverse psychotomimetics act through a common signaling pathway. Science (New York, N.Y.). 302: 1412-5. PMID 14631045 DOI: 10.1126/science.1089681  1
2003 Fink-Jensen A, Fedorova I, Wörtwein G, Woldbye DP, Rasmussen T, Thomsen M, Bolwig TG, Knitowski KM, McKinzie DL, Yamada M, Wess J, Basile A. Role for M5 muscarinic acetylcholine receptors in cocaine addiction. Journal of Neuroscience Research. 74: 91-6. PMID 13130510 DOI: 10.1002/jnr.10728  1
2003 Tzavara ET, Bymaster FP, Felder CC, Wade M, Gomeza J, Wess J, McKinzie DL, Nomikos GG. Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice. Molecular Psychiatry. 8: 673-9. PMID 12874603 DOI: 10.1038/sj.mp.4001270  1
2003 Bymaster FP, Carter PA, Yamada M, Gomeza J, Wess J, Hamilton SE, Nathanson NM, McKinzie DL, Felder CC. Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. The European Journal of Neuroscience. 17: 1403-10. PMID 12713643 DOI: 10.1046/j.1460-9568.2003.02588.x  1
2003 Bymaster FP, McKinzie DL, Felder CC, Wess J. Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system. Neurochemical Research. 28: 437-42. PMID 12675128 DOI: 10.1023/A:1022844517200  1
2003 Rodd-Henricks ZA, McKinzie DL, Melendez RI, Berry N, Murphy JM, McBride WJ. Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats. Psychopharmacology. 165: 252-9. PMID 12447605 DOI: 10.1007/s00213-002-1300-2  1
2002 Bymaster FP, Felder C, Ahmed S, McKinzie D. Muscarinic receptors as a target for drugs treating schizophrenia. Current Drug Targets. Cns and Neurological Disorders. 1: 163-81. PMID 12769625  1
2002 Rodd-Henricks ZA, McKinzie DL, Li TK, Murphy JM, McBride WJ. Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats. The Journal of Pharmacology and Experimental Therapeutics. 303: 1216-26. PMID 12438546 DOI: 10.1124/jpet.102.038950  1
2002 McKinzie DL, McBride WJ, Murphy JM, Lumeng L, Li TK. Effects of amphetamine on locomotor activity in adult and juvenile alcohol-preferring and -nonpreferring rats. Pharmacology, Biochemistry, and Behavior. 71: 29-36. PMID 11812505 DOI: 10.1016/S0091-3057(01)00610-4  1
2001 Yamada M, Lamping KG, Duttaroy A, Zhang W, Cui Y, Bymaster FP, McKinzie DL, Felder CC, Deng CX, Faraci FM, Wess J. Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 14096-101. PMID 11707605 DOI: 10.1073/pnas.251542998  1
2001 Felder CC, Porter AC, Skillman TL, Zhang L, Bymaster FP, Nathanson NM, Hamilton SE, Gomeza J, Wess J, McKinzie DL. Elucidating the role of muscarinic receptors in psychosis. Life Sciences. 68: 2605-13. PMID 11392633 DOI: 10.1016/S0024-3205(01)01059-1  1
2000 McKinzie DL, Li TK, McBride WJ, Slusher BS. NAALADase inhibition reduces alcohol consumption in the alcohol-preferring (P) line of rats. Addiction Biology. 5: 411-6. PMID 20575858 DOI: 10.1111/j.1369-1600.2000.tb00209.x  1
2000 Bell RL, McKinzie DL, Murphy JM, McBride WJ. Sensitivity and tolerance to the motor impairing effects of moderate doses of ethanol. Pharmacology, Biochemistry, and Behavior. 67: 583-6. PMID 11164089 DOI: 10.1016/S0091-3057(00)00387-7  1
2000 Jones AE, McBride WJ, Murphy JM, Lumeng L, Li T, Shekhar A, McKinzie DL. Effects of ethanol on startle responding in alcohol-preferring and -non-preferring rats. Pharmacology, Biochemistry, and Behavior. 67: 313-8. PMID 11124395 DOI: 10.1016/S0091-3057(00)00363-4  1
2000 McKinzie DL, McBride WJ, Murphy JM, Lumeng L, Li TK. Effects of MDL 72222, a serotonin3 antagonist, on operant responding for ethanol by alcohol-preferring P rats. Alcoholism, Clinical and Experimental Research. 24: 1500-4. PMID 11045857  1
2000 Rodd-Henricks ZA, McKinzie DL, Edmundson VE, Dagon CL, Murphy JM, McBride WJ, Lumeng L, Li TK. Effects of 5-HT(3) receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats. Alcohol (Fayetteville, N.Y.). 21: 73-85. PMID 10946160 DOI: 10.1016/S0741-8329(00)00083-5  1
2000 Rodd-Henricks ZA, McKinzie DL, Murphy JM, McBride WJ, Lumeng L, Li TK. The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations. Alcoholism, Clinical and Experimental Research. 24: 747-53. PMID 10888060  1
2000 Nowak KL, Ingraham CM, Mckinzie DL, Mcbride WJ, Lumeng L, Li TK, Murphy JM. An assessment of novelty-seeking behavior in alcohol-preferring and nonpreferring rats. Pharmacology, Biochemistry, and Behavior. 66: 113-21. PMID 10837850 DOI: 10.1016/S0091-3057(00)00206-9  1
2000 Rodd-Henricks ZA, McKinzie DL, Crile RS, Murphy JM, McBride WJ. Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats. Psychopharmacology. 149: 217-24. PMID 10823401 DOI: 10.1007/s002139900347  1
2000 Mckinzie DL, Sajdyk TJ, Mcbride WJ, Murphy JM, Lumeng L, Li TK, Shekhar A. Acoustic startle and fear-potentiated startle in alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacology, Biochemistry, and Behavior. 65: 691-6. PMID 10764924 DOI: 10.1016/S0091-3057(99)00252-X  1
2000 Rodd-Henricks ZA, McKinzie DL, Shaikh SR, Murphy JM, McBride WJ, Lumeng L, Li TK. Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations. Alcoholism, Clinical and Experimental Research. 24: 8-16. PMID 10656186  1
1999 McKinzie DL, Cox R, Murphy JM, Li TK, Lumeng L, McBride WJ. Voluntary ethanol drinking during the first three postnatal weeks in lines of rats selectively bred for divergent ethanol preference. Alcoholism, Clinical and Experimental Research. 23: 1892-7. PMID 10630607  1
1999 Nowak KL, McKinzie DL, McBride WJ, Murphy JM. Patterns of ethanol and saccharin intake in P rats under limited-access conditions. Alcohol (Fayetteville, N.Y.). 19: 85-96. PMID 10487392 DOI: 10.1016/S0741-8329(99)00028-2  1
1999 McKinzie DL, Rodd-Henricks ZA, Dagon CT, Murphy JM, McBride WJ. Cocaine is self-administered into the shell region of the nucleus accumbens in Wistar rats. Annals of the New York Academy of Sciences. 877: 788-91. PMID 10415705 DOI: 10.1111/j.1749-6632.1999.tb09323.x  1
1998 McBride WJ, Chernet E, McKinzie DL, Lumeng L, Li TK. Quantitative autoradiography of mu-opioid receptors in the CNS of alcohol-naive alcohol-preferring P and -nonpreferring NP rats. Alcohol (Fayetteville, N.Y.). 16: 317-23. PMID 9818984 DOI: 10.1016/S0741-8329(98)00021-4  1
1998 McKinzie DL, Nowak KL, Murphy JM, Li TK, Lumeng L, McBride WJ. Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference. Alcoholism, Clinical and Experimental Research. 22: 1584-90. PMID 9802545  1
1998 McKinzie DL, Chen WJ, Spear NE. Ontogenetic differences in the expression of conditioned stimulus conditioning: effects of retention interval. Behavioral Neuroscience. 112: 920-8. PMID 9733198 DOI: 10.1037//0735-7044.112.4.920  1
1998 McKinzie DL, Nowak KL, Yorger L, McBride WJ, Murphy JM, Lumeng L, Li TK. The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions. Alcoholism, Clinical and Experimental Research. 22: 1170-6. PMID 9726292  1
1998 McKinzie DL, Eha R, Cox R, Stewart RB, Dyr W, Murphy JM, McBride WJ, Lumeng L, Li TK. Serotonin3 receptor antagonism of alcohol intake: effects of drinking conditions. Alcohol (Fayetteville, N.Y.). 15: 291-8. PMID 9590513 DOI: 10.1016/S0741-8329(97)00132-8  1
1998 Zhou FC, McKinzie DL, Patel TD, Lumeng L, Li TK. Additive reduction of alcohol drinking by 5-HT1A antagonist WAY 100635 and serotonin uptake blocker fluoxetine in alcohol-preferring P rats. Alcoholism, Clinical and Experimental Research. 22: 266-9. PMID 9514317  1
1996 Molina JC, Bannoura MD, Chotro MG, McKinzie DL, Arnold HM, Spear NE. Alcohol-mediated tactile conditioned aversions in infant rats: devaluation of conditioning through alcohol-sucrose associations. Neurobiology of Learning and Memory. 66: 121-32. PMID 8946405 DOI: 10.1006/nlme.1996.0053  1
1996 Chotro MG, Kraebel KS, McKinzie DL, Molina JC, Spear N. Prenatal and postnatal ethanol exposure influences preweanling rats' behavioral and autonomic responding to ethanol odor. Alcohol (Fayetteville, N.Y.). 13: 377-85. PMID 8836327 DOI: 10.1016/0741-8329(96)00027-4  1
1996 McKinzie DL, Eha R, Murphy JM, McBride WJ, Lumeng L, Li TK. Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD rat lines. Alcoholism, Clinical and Experimental Research. 20: 682-7. PMID 8800385 DOI: 10.1111/j.1530-0277.1996.tb01672.x  1
1996 Salimov RM, McBride WJ, McKinzie DL, Lumeng L, Li TK. Effects of ethanol consumption by adolescent alcohol-preferring P rats on subsequent behavioral performance in the cross-maze and slip funnel tests. Alcohol (Fayetteville, N.Y.). 13: 297-300. PMID 8734846 DOI: 10.1016/0741-8329(95)02060-8  1
1996 Wenger MJ, McKinzie DL. Ontogenetic differences in variability on simple measures of learning: theoretical and practical implications. Developmental Psychobiology. 29: 219-39. PMID 8666130 DOI: 10.1002/(SICI)1098-2302(199604)29:3<219::AID-DEV3>3.0.CO;2-U  1
1996 Miller JS, McKinzie DL, Kraebel KS, Spear NE. Changes in the expression of stimulus selection: Blocking represents selective memory retrieval rather than selective associations Learning and Motivation. 27: 307-316. DOI: 10.1006/lmot.1996.0017  1
1996 McKinzie DL, Lee JS, McKinzie JH, Spear LP, Spear NE. Ontogenetic differences in ethanol-induced impairment of context and CS learning Psychobiology. 24: 306-313.  1
1995 Mckinzie DL, Spear NE. Ontogenetic differences in conditioning to context and CS as a function of context saliency and CS-US interval Animal Learning & Behavior. 23: 304-313. DOI: 10.3758/BF03198927  1
1994 McKinzie DL, Lee J, Bronfen JH, Spear LP, Spear NE. Context and tone conditioning are selectively impaired by ethanol in the preweanling rat: effects of dose and time of administration. Behavioral and Neural Biology. 62: 201-9. PMID 7857242 DOI: 10.1016/S0163-1047(05)80018-4  1
1994 Heyser CJ, McKinzie DL, Athalie F, Spear NE, Spear LP. Effects of prenatal exposure to cocaine on heart rate and nonassociative learning and retention in infant rats. Teratology. 49: 470-8. PMID 7747268 DOI: 10.1002/tera.1420490607  1
1992 Goodwin GA, Heyser CJ, Moody CA, Rajachandran L, Molina VA, Arnold HM, McKinzie DL, Spear NE, Spear LP. A fostering study of the effects of prenatal cocaine exposure: II. Offspring behavioral measures. Neurotoxicology and Teratology. 14: 423-32. PMID 1488037 DOI: 10.1016/0892-0362(92)90053-D  1
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