Niklas Marklund - Publications

Affiliations: 
Uppsala University, Uppsala, Uppsala län, Sweden 

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Michalettos G, Clausen F, Özen I, Ruscher K, Marklund N. Impaired oligodendrogenesis in the white matter of aged mice following diffuse traumatic brain injury. Glia. PMID 38180164 DOI: 10.1002/glia.24499  0.414
2023 Garza R, Sharma Y, Atacho DAM, Thiruvalluvan A, Abu Hamdeh S, Jönsson ME, Horvath V, Adami A, Ingelsson M, Jern P, Hammell MG, Englund E, Kirkeby A, Jakobsson J, Marklund N. Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia. Cell Reports. 42: 113395. PMID 37967557 DOI: 10.1016/j.celrep.2023.113395  0.387
2023 Klang A, Molero Y, Lichtenstein P, Larsson H, D'Onofrio BM, Marklund N, Oldenburg C, Rostami E. Access to Rehabilitation After Hospitalization for Traumatic Brain Injury: A National Longitudinal Cohort Study in Sweden. Neurorehabilitation and Neural Repair. 37: 763-774. PMID 37953612 DOI: 10.1177/15459683231209315  0.499
2023 Hossain I, Rostami E, Marklund N. The management of severe traumatic brain injury in the initial postinjury hours - current evidence and controversies. Current Opinion in Critical Care. 29: 650-658. PMID 37851061 DOI: 10.1097/MCC.0000000000001094  0.463
2023 Gard A, Vedung F, Piehl F, Khademi M, Wernersson MP, Rorsman I, Tegner Y, Pessah-Rasmussen H, Ruscher K, Marklund N. Cerebrospinal fluid levels of neuroinflammatory biomarkers are increased in athletes with persistent post-concussive symptoms following sports-related concussion. Journal of Neuroinflammation. 20: 189. PMID 37592277 DOI: 10.1186/s12974-023-02864-0  0.302
2023 Marklund N. Did early studies of human traumatic brain injury overlook concomitant oligodendrocyte pathology in injured white matter tracts? A comment on "Detection and verification of neurodegeneration after traumatic brain injury in the mouse: Immunohistochemical staining for amyloid precursor protein". Brain Pathology (Zurich, Switzerland). PMID 37347524 DOI: 10.1111/bpa.13179  0.491
2023 Marklund N, Brody DL. Refined Management of Severe Traumatic Brain Injury in Children. Journal of Neurotrauma. 40: 1027-1028. PMID 37262426 DOI: 10.1089/neu.2021.29122.editorial  0.404
2023 Iaccarino C, Carretta A, Demetriades AK, Di Minno G, Giussani C, Marcucci R, Marklund N, Mastrojanni G, Pompucci A, Stefini R, Zona G, Cividini A, Petrella G, Coluccio V, Marietta M. Management of Antithrombotic Drugs in Patients with Isolated Traumatic Brain Injury: An Intersociety Consensus Document. Neurocritical Care. PMID 37029314 DOI: 10.1007/s12028-023-01715-3  0.401
2023 Cederberg D, Visse E, Marklund N, Siesjö P. Prolonged and intense neuroinflammation after severe traumatic brain injury assessed by cerebral microdialysis with 300 kDa membranes. Journal of Neuroimmunology. 377: 578020. PMID 36931209 DOI: 10.1016/j.jneuroim.2023.578020  0.457
2023 Rostami E, Ginstman F, Ljungqvist J, Olivecrona M, Koskinen LO, Bellander BM, Marklund N. [Treatment of traumatic brain injury in the acute setting - An overview]. Lakartidningen. 120. PMID 36714930  0.485
2023 Réen L, Cederberg D, Radman A, Marklund N, Visse E, Siesjö P. Low Morbidity and Mortality in Children with Severe Traumatic Brain Injury Treated According to the Lund Concept: A Population-Based Study. Journal of Neurotrauma. PMID 36472219 DOI: 10.1089/neu.2022.0116  0.315
2022 Al-Husseini A, Fazel Bakhsheshi M, Gard A, Tegner Y, Marklund N. Shorter Recovery Time in Concussed Elite Ice Hockey Players by Early Head-and-Neck Cooling: A Clinical Trial. Journal of Neurotrauma. PMID 36222612 DOI: 10.1089/neu.2022.0248  0.316
2022 Al-Husseini A, Gard A, Fransson PA, Tegner Y, Magnusson M, Marklund N, Tjernström F. Long-term postural control in elite athletes following mild traumatic brain injury. Frontiers in Neurology. 13: 906594. PMID 36172026 DOI: 10.3389/fneur.2022.906594  0.379
2022 Özen I, Mai H, De Maio A, Ruscher K, Michalettos G, Clausen F, Gottschalk M, Ansar S, Arkan S, Erturk A, Marklund N. Purkinje cell vulnerability induced by diffuse traumatic brain injury is linked to disruption of long-range neuronal circuits. Acta Neuropathologica Communications. 10: 129. PMID 36064443 DOI: 10.1186/s40478-022-01435-3  0.491
2022 Vedung F, Fahlström M, Wall A, Antoni G, Lubberink M, Johansson J, Tegner Y, Stenson S, Haller S, Weis J, Larsson EM, Marklund N. Chronic cerebral blood flow alterations in traumatic brain injury and sports-related concussions. Brain Injury. 1-13. PMID 35950271 DOI: 10.1080/02699052.2022.2109746  0.418
2022 Tsitsopoulos PP, Mondello S, Holmström U, Marklund N. Cerebrospinal fluid biomarkers of white matter injury and astrogliosis are associated with the severity and surgical outcome of degenerative cervical spondylotic myelopathy. The Spine Journal : Official Journal of the North American Spine Society. PMID 35753639 DOI: 10.1016/j.spinee.2022.06.012  0.313
2022 Latini F, Fahlström M, Vedung F, Stensson S, Larsson EM, Lubberink M, Tegner Y, Haller S, Johansson J, Wall A, Antoni G, Marklund N. Refined Analysis of Chronic White Matter Changes after Traumatic Brain Injury and Repeated Sports-Related Concussions: Of Use in Targeted Rehabilitative Approaches? Journal of Clinical Medicine. 11. PMID 35054052 DOI: 10.3390/jcm11020358  0.439
2022 Ozen I, Arkan S, Clausen F, Ruscher K, Marklund N. Diffuse traumatic injury in the mouse disrupts axon-myelin integrity in the cerebellum. Journal of Neurotrauma. PMID 35018831 DOI: 10.1089/neu.2021.0321  0.392
2021 Tobieson L, Gard A, Ruscher K, Marklund N. Intracerebral Proinflammatory Cytokine Increase in Surgically Evacuated Intracerebral Hemorrhage: A Microdialysis Study. Neurocritical Care. PMID 34850333 DOI: 10.1007/s12028-021-01389-9  0.414
2021 Tobieson L, Zetterberg H, Blennow K, Marklund N. Extracellular fluid, cerebrospinal fluid and plasma biomarkers of axonal and neuronal injury following intracerebral hemorrhage. Scientific Reports. 11: 16950. PMID 34417515 DOI: 10.1038/s41598-021-96364-x  0.311
2021 Abu Hamdeh S, Tenovuo O, Peul W, Marklund N. "Omics" in traumatic brain injury: novel approaches to a complex disease. Acta Neurochirurgica. PMID 34273044 DOI: 10.1007/s00701-021-04928-7  0.449
2021 Bakalkin G, Nosova O, Sarkisyan D, Hallberg M, Zhang M, Schouenborg J, Marklund N, Watanabe H. Unilateral traumatic brain injury of the left and right hemisphere produces the left hindlimb response in rats. Experimental Brain Research. PMID 34021800 DOI: 10.1007/s00221-021-06118-4  0.378
2021 Marklund N, Vedung F, Lubberink M, Tegner Y, Johansson J, Blennow K, Zetterberg H, Fahlström M, Haller S, Stenson S, Larsson EM, Wall A, Antoni G. Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients - A PET/MR study. Neuroimage. Clinical. 30: 102665. PMID 33894460 DOI: 10.1016/j.nicl.2021.102665  0.366
2020 Watanabe H, Nosova O, Sarkisyan D, Andersen MS, Zhang M, Rorick-Kehn L, Clausen F, Gawel K, Kehr J, Hallberg M, Schouenborg J, Marklund N, Bakalkin G. Ipsilesional contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism. Brain Communications. 2: fcaa208. PMID 33364602 DOI: 10.1093/braincomms/fcaa208  0.367
2020 Abu Hamdeh S, Ciuculete DM, Sarkisyan D, Bakalkin G, Ingelsson M, Schiöth H, Marklund N. Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury. Journal of Neurotrauma. PMID 33191850 DOI: 10.1089/neu.2020.7283  0.308
2020 Rostami E, Kongstad P, Marklund N. [Should all patients with traumatic brain injury receive tranexamic acid?] Lakartidningen. 117. PMID 33021328  0.47
2020 Tobieson L, Czifra Z, Wåhlén K, Marklund N, Ghafouri B. Proteomic investigation of protein adsorption to cerebral microdialysis membranes in surgically treated intracerebral hemorrhage patients - a pilot study. Proteome Science. 18: 7. PMID 32728348 DOI: 10.1186/S12953-020-00163-7  0.302
2020 Holmström U, Tsitsopoulos PP, Holtz A, Salci K, Shaw G, Mondello S, Marklund N. Cerebrospinal fluid levels of GFAP and pNF-H are elevated in patients with chronic spinal cord injury and neurological deterioration. Acta Neurochirurgica. PMID 32588294 DOI: 10.1007/S00701-020-04422-6  0.327
2020 Tsitsopoulos PP, Marklund N, Rostami E, Enblad P, Hillered L. Association of the bleeding time test with aspects of traumatic brain injury in patients with alcohol use disorder. Acta Neurochirurgica. 162: 1597-1606. PMID 32424564 DOI: 10.1007/S00701-020-04373-Y  0.517
2020 Clark D, Joannides A, Ibrahim Abdallah O, Olufemi Adeleye A, Hafid Bajamal A, Bashford T, Bhebhe A, Biluts H, Budohoska N, Budohoski K, Cherian I, Marklund N, Fernandez Mendez R, Figaji T, Kumar Gupta D, et al. Management and outcomes following emergency surgery for traumatic brain injury - A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study). International Journal of Surgery Protocols. 20: 1-7. PMID 32211566 DOI: 10.1016/J.Isjp.2020.02.001  0.545
2020 Ozen I, Ruscher K, Nilsson R, Flygt J, Clausen F, Marklund N. Interleukin-1 Beta Neutralization Attenuates Traumatic Brain Injury-Induced Microglia Activation and Neuronal Changes in the Globus Pallidus. International Journal of Molecular Sciences. 21. PMID 31936248 DOI: 10.3390/Ijms21020387  0.513
2019 Marklund N, Bellander BM, Godbolt A, Levin H, McCrory P, Thelin EP. Treatments and rehabilitation in the acute and chronic state of traumatic brain injury. Journal of Internal Medicine. PMID 30883980 DOI: 10.1111/Joim.12900  0.56
2019 Kononenko O, Watanabe H, Stålhandske L, Zarelius A, Clausen F, Yakovleva T, Bakalkin G, Marklund N. Focal traumatic brain injury induces neuroplastic molecular response in lumbar spinal cord. Restorative Neurology and Neuroscience. PMID 30856132 DOI: 10.3233/Rnn-180882  0.423
2019 Reinstrup P, Unnerbäck M, Marklund N, Schalen W, Arrocha JC, Bloomfield EL, Sadegh V, Hesselgard K. Best zero level for external ICP transducer. Acta Neurochirurgica. PMID 30848373 DOI: 10.1007/S00701-019-03856-X  0.33
2019 Tobieson L, Ghafouri B, Zsigmond P, Rossitti S, Hillman J, Marklund N. Dynamic protein changes in the perihaemorrhagic zone of Surgically Treated Intracerebral Haemorrhage Patients. Scientific Reports. 9: 3181. PMID 30816204 DOI: 10.1038/S41598-019-39499-2  0.354
2019 Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, ... ... Marklund N, et al. Primum non nocere: a call for balance when reporting on CTE. The Lancet. Neurology. 18: 231-233. PMID 30784550 DOI: 10.1016/S1474-4422(19)30020-1  0.575
2019 Wang C, Iashchishyn IA, Kara J, Foderà V, Vetri V, Sancataldo G, Marklund N, Morozova-Roche LA. Proinflammatory and Amyloidogenic S100A9 Induced by Traumatic Brain Injury in Mouse Model. Neuroscience Letters. PMID 30753908 DOI: 10.1016/J.Neulet.2019.02.012  0.532
2019 Hubertus V, Marklund N, Vajkoczy P. Management of concussion in soccer. Acta Neurochirurgica. PMID 30687899 DOI: 10.1007/S00701-019-03807-6  0.399
2018 Abu Hamdeh S, Marklund N, Lewén A, Howells T, Raininko R, Wikström J, Enblad P. Intracranial pressure elevations in diffuse axonal injury: association with nonhemorrhagic MR lesions in central mesencephalic structures. Journal of Neurosurgery. 1-8. PMID 30215559 DOI: 10.3171/2018.4.Jns18185  0.389
2018 Baunsgaard CB, Nissen UV, Brust AK, Frotzler A, Ribeill C, Kalke YB, León N, Gómez B, Samuelsson K, Antepohl W, Holmström U, Marklund N, Glott T, Opheim A, Benito Penalva J, et al. Exoskeleton gait training after spinal cord injury: An exploratory study on secondary health conditions. Journal of Rehabilitation Medicine. PMID 30183055 DOI: 10.2340/16501977-2372  0.332
2018 Clausen F, Marklund N, Hillered L. Acute inflammatory biomarker responses to diffuse traumatic brain injury in the rat monitored by a novel microdialysis technique. Journal of Neurotrauma. PMID 29790398 DOI: 10.1089/Neu.2018.5636  0.654
2018 Tobieson L, Rossitti S, Zsigmond P, Hillman J, Marklund N. Persistent Metabolic Disturbance in the Perihemorrhagic Zone Despite a Normalized Cerebral Blood Flow Following Surgery for Intracerebral Hemorrhage. Neurosurgery. PMID 29788388 DOI: 10.1093/Neuros/Nyy179  0.328
2018 Abu Hamdeh S, Shevchenko G, Mi J, Musunuri S, Bergquist J, Marklund N. Proteomic differences between focal and diffuse traumatic brain injury in human brain tissue. Scientific Reports. 8: 6807. PMID 29717219 DOI: 10.1038/S41598-018-25060-0  0.528
2018 Flygt J, Ruscher K, Norberg A, Mir A, Gram H, Clausen F, Marklund N. Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse attenuates the loss of Mature Oligodendrocytes. Journal of Neurotrauma. PMID 29690837 DOI: 10.1089/Neu.2018.5660  0.524
2018 Shahim P, Tegner Y, Marklund N, Blennow K, Zetterberg H. Neurofilament light and tau as blood biomarkers for sports-related concussion. Neurology. PMID 29653990 DOI: 10.1212/Wnl.0000000000005518  0.363
2018 Thelin EP, Helmy A, Nelson DW, Marklund N. Editorial: Monitoring Pathophysiology in the Injured Brain. Frontiers in Neurology. 9: 193. PMID 29632512 DOI: 10.3389/Fneur.2018.00193  0.602
2018 Abu Hamdeh S, Virhammar J, Sehlin D, Alafuzoff I, Cesarini KG, Marklund N. Brain tissue Aβ42 levels are linked to shunt response in idiopathic normal pressure hydrocephalus. Journal of Neurosurgery. 1-9. PMID 29350601 DOI: 10.3171/2017.7.Jns171005  0.337
2017 Tsitsopoulos PP, Abu Hamdeh S, Marklund N. Current Opportunities for Clinical Monitoring of Axonal Pathology in Traumatic Brain Injury. Frontiers in Neurology. 8: 599. PMID 29209266 DOI: 10.3389/Fneur.2017.00599  0.534
2017 Bach Baunsgaard C, Vig Nissen U, Katrin Brust A, Frotzler A, Ribeill C, Kalke YB, León N, Gómez B, Samuelsson K, Antepohl W, Holmström U, Marklund N, Glott T, Opheim A, Benito J, et al. Gait training after spinal cord injury: safety, feasibility and gait function following 8 weeks of training with the exoskeletons from Ekso Bionics. Spinal Cord. PMID 29105657 DOI: 10.1038/S41393-017-0013-7  0.316
2017 Marklund N. The Neurological Wake-up Test-A Role in Neurocritical Care Monitoring of Traumatic Brain Injury Patients? Frontiers in Neurology. 8: 540. PMID 29089921 DOI: 10.3389/Fneur.2017.00540  0.479
2017 Maegele M, Schöchl H, Menovsky T, Maréchal H, Marklund N, Buki A, Stanworth S. Coagulopathy and haemorrhagic progression in traumatic brain injury: advances in mechanisms, diagnosis, and management. The Lancet. Neurology. 16: 630-647. PMID 28721927 DOI: 10.1016/S1474-4422(17)30197-7  0.495
2017 Vedung F, Antoni G, Wall A, Fahlström M, Larsson E, Marklund N. Persistent Decrease Of Cerebral Blood Flow In Traumatic Brain Injury And Sports-Related Concussion Journal of Neurotrauma. 34. PMID 28661788 DOI: 10.1089/Neu.2017.29011.Abstracts  0.517
2017 Abu Hamdeh S, Waara ER, Möller C, Söderberg L, Basun H, Alafuzoff I, Hillered L, Lannfelt L, Ingelsson M, Marklund N. Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury. Brain Pathology (Zurich, Switzerland). PMID 28557010 DOI: 10.1111/Bpa.12532  0.624
2017 Marklund N. Michael G. Fehlings, Norbert Weidner (guest eds), Luiz R.G. Vialle (series ed): AOSpine masters series, vol 7: Spinal cord injury and regeneration : Thieme, New York Stuttgart, 2016, hardback, 225 pp., 50 illustrations (ISBN 9781626232273, eISBN 9781626232280) € 109.99/US$ 119.99. Acta Neurochirurgica. PMID 28510778 DOI: 10.1007/S00701-017-3210-4  0.324
2017 Wicher G, Wallenquist U, Lei Y, Enoksson M, Li X, Fuchs B, Abu Hamdeh S, Marklund N, Hillered L, Nilsson G, Forsberg-Nilsson K. IL-33 promotes recruitment of microglia/macrophages in response to traumatic brain injury. Journal of Neurotrauma. PMID 28490277 DOI: 10.1089/Neu.2016.4900  0.707
2017 Shahim P, Tegner Y, Marklund N, Höglund K, Portelius E, Brody DL, Blennow K, Zetterberg H. Astroglial activation and altered amyloid metabolism in human repetitive concussion. Neurology. PMID 28283595 DOI: 10.1212/Wnl.0000000000003816  0.474
2017 Clausen F, Hansson HA, Raud J, Marklund N. Intranasal Administration of the Antisecretory Peptide AF-16 Reduces Edema and Improves Cognitive Function Following Diffuse Traumatic Brain Injury in the Rat. Frontiers in Neurology. 8: 39. PMID 28261150 DOI: 10.3389/Fneur.2017.00039  0.564
2016 Marklund N. Cerebral amyloid angiopathy: a long-term consequence of traumatic brain injury? Acta Neurochirurgica. PMID 27796651 DOI: 10.1007/S00701-016-3005-Z  0.529
2016 Flygt J, Clausen F, Marklund N. Diffuse traumatic brain injury in the mouse induces a transient proliferation of oligodendrocyte progenitor cells in injured white matter tracts. Restorative Neurology and Neuroscience. PMID 27768001 DOI: 10.3233/Rnn-160675  0.553
2016 Marklund N. Rodent Models of Traumatic Brain Injury: Methods and Challenges. Methods in Molecular Biology (Clifton, N.J.). 1462: 29-46. PMID 27604711 DOI: 10.1007/978-1-4939-3816-2_3  0.508
2016 Abu Hamdeh S, Marklund N, Lannsjö M, Howells T, Raininko R, Wikström J, Enblad P. Extended anatomical grading in diffuse axonal injury using MRI - Hemorrhagic lesions in the substantia nigra and mesencephalic tegmentum indicate poor long-term outcome. Journal of Neurotrauma. PMID 27356857 DOI: 10.1089/Neu.2016.4426  0.327
2016 Shariatgorji M, Nilsson A, Bonta M, Gan J, Marklund N, Clausen F, Källback P, Loden H, Limbeck A, Andren PE. Direct Imaging of Elemental Distributions in Tissue Sections by Laser Ablation Mass Spectrometry. Methods (San Diego, Calif.). PMID 27263025 DOI: 10.1016/J.Ymeth.2016.05.021  0.32
2016 Flygt J, Gumucio A, Ingelsson M, Skoglund K, Holm J, Alafuzoff I, Marklund N. Human Traumatic Brain Injury Results in Oligodendrocyte Death and Increases the Number of Oligodendrocyte Progenitor Cells. Journal of Neuropathology and Experimental Neurology. PMID 27105664 DOI: 10.1093/Jnen/Nlw025  0.551
2016 Ekmark-Lewén S, Flygt J, Fridgeirsdottir GA, Kiwanuka O, Hånell A, Meyerson BJ, Mir AK, Gram H, Lewén A, Clausen F, Hillered L, Marklund N. Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β. The European Journal of Neuroscience. 43: 1016-33. PMID 27091435 DOI: 10.1111/Ejn.13190  0.691
2016 Hopp S, Albert-Weissenberger C, Mencl S, Bieber M, Schuhmann MK, Stetter C, Nieswandt B, Schmidt PM, Monoranu CM, Alafuzoff I, Marklund N, Nolte MW, Sirén AL, Kleinschnitz C. Targeting Coagulation Factor XII as a Novel Therapeutic Option in Brain Trauma. Annals of Neurology. PMID 27043916 DOI: 10.1002/Ana.24655  0.528
2015 Hutchinson PJ, Jalloh I, Helmy A, Carpenter KL, Rostami E, Bellander BM, Boutelle MG, Chen JW, Claassen J, Dahyot-Fizelier C, Enblad P, Gallagher CN, Helbok R, Hillered L, Le Roux PD, ... ... Marklund N, et al. Consensus statement from the 2014 International Microdialysis Forum. Intensive Care Medicine. PMID 26194024 DOI: 10.1007/S00134-015-3930-Y  0.592
2015 Hutchinson PJ, Jalloh I, Helmy A, Carpenter KLH, Rostami E, Bellander BM, Boutelle MG, Chen JW, Claassen J, Dahyot-Fizelier C, Enblad P, Gallagher CN, Helbok R, Hillered L, Le Roux PD, ... ... Marklund N, et al. Consensus statement from the 2014 International Microdialysis Forum Intensive Care Medicine. DOI: 10.1007/s00134-015-3930-y  0.442
2014 Israelsson C, Flygt J, Åstrand E, Kiwanuka O, Bengtsson H, Marklund N. Altered expression of myelin-associated inhibitors and their receptors after traumatic brain injury in the mouse. Restorative Neurology and Neuroscience. 32: 717-31. PMID 25079982 DOI: 10.3233/Rnn-140419  0.489
2014 Ronne-Engström E, Borota L, Kothimbakam R, Marklund N, Lewén A, Enblad P. Outcome from spontaneous subarachnoid haemorrhage--results from 2007-2011 and comparison with our previous series. Upsala Journal of Medical Sciences. 119: 38-43. PMID 24147458 DOI: 10.3109/03009734.2013.849781  0.315
2014 Skoglund K, Hillered L, Purins K, Tsitsopoulos PP, Flygt J, Engquist H, Lewén A, Enblad P, Marklund N. The neurological wake-up test does not alter cerebral energy metabolism and oxygenation in patients with severe traumatic brain injury. Neurocritical Care. 20: 413-26. PMID 23934408 DOI: 10.1007/S12028-013-9876-4  0.683
2014 Marklund N, Farrokhnia N, HÃ¥nell A, Vanmechelen E, Enblad P, Zetterberg H, Blennow K, Hillered L. Monitoring of β-amyloid dynamics after human traumatic brain injury. Journal of Neurotrauma. 31: 42-55. PMID 23829439 DOI: 10.1089/Neu.2013.2964  0.715
2013 Skoglund K, Enblad P, Marklund N. Monitoring and sedation differences in the management of severe head injury and subarachnoid hemorrhage among neurocritical care centers. The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses. 45: 360-8. PMID 24217146 DOI: 10.1097/Jnn.0B013E3182A3Cf4F  0.489
2013 Tsitsopoulos PP, Enblad P, Wanhainen A, Tobieson L, HÃ¥rdemark HG, Marklund N. Improved outcome of patients with severe thalamic hemorrhage treated with cerebrospinal fluid drainage and neurocritical care during 1990-1994 and 2005-2009. Acta Neurochirurgica. 155: 2105-13. PMID 24026230 DOI: 10.1007/S00701-013-1871-1  0.304
2013 Tsitsopoulos PP, Marklund N. Amyloid-β Peptides and Tau Protein as Biomarkers in Cerebrospinal and Interstitial Fluid Following Traumatic Brain Injury: A Review of Experimental and Clinical Studies. Frontiers in Neurology. 4: 79. PMID 23805125 DOI: 10.3389/Fneur.2013.00079  0.488
2013 Ekmark-Lewén S, Flygt J, Kiwanuka O, Meyerson BJ, Lewén A, Hillered L, Marklund N. Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes. Journal of Neuroinflammation. 10: 44. PMID 23557178 DOI: 10.1186/1742-2094-10-44  0.713
2013 Flygt J, Djupsjö A, Lenne F, Marklund N. Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat. The European Journal of Neuroscience. 38: 2153-65. PMID 23458840 DOI: 10.1111/Ejn.12179  0.514
2013 Axelson HW, Winkler T, Flygt J, Djupsjö A, HÃ¥nell A, Marklund N. Plasticity of the contralateral motor cortex following focal traumatic brain injury in the rat. Restorative Neurology and Neuroscience. 31: 73-85. PMID 23047494 DOI: 10.3233/Rnn-2012-120242  0.55
2012 HÃ¥nell A, Clausen F, Djupsjö A, Vallstedt A, Patra K, Israelsson C, Larhammar M, Björk M, Paixão S, Kullander K, Marklund N. Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice. Journal of Neurotrauma. 29: 2660-71. PMID 22985250 DOI: 10.1089/Neu.2012.2376  0.546
2012 Hånell A, Hedin J, Clausen F, Marklund N. Facilitated assessment of tissue loss following traumatic brain injury. Frontiers in Neurology. 3: 29. PMID 22435063 DOI: 10.3389/Fneur.2012.00029  0.459
2012 Wallenquist U, Holmqvist K, HÃ¥nell A, Marklund N, Hillered L, Forsberg-Nilsson K. Ibuprofen attenuates the inflammatory response and allows formation of migratory neuroblasts from grafted stem cells after traumatic brain injury. Restorative Neurology and Neuroscience. 30: 9-19. PMID 22377906 DOI: 10.3233/Rnn-2011-0606  0.635
2012 Skoglund K, Enblad P, Hillered L, Marklund N. The neurological wake-up test increases stress hormone levels in patients with severe traumatic brain injury. Critical Care Medicine. 40: 216-22. PMID 22179339 DOI: 10.1097/Ccm.0B013E31822D7Dbd  0.668
2012 Clausen F, Marklund N, Lewén A, Enblad P, Basu S, Hillered L. Interstitial F(2)-isoprostane 8-iso-PGF(2α) as a biomarker of oxidative stress after severe human traumatic brain injury. Journal of Neurotrauma. 29: 766-75. PMID 21639729 DOI: 10.1089/Neu.2011.1754  0.666
2012 Skoglund K, Enblad P, Hillered L, Marklund N. The authors reply Critical Care Medicine. 40: 2002-2003. DOI: 10.1097/Ccm.0B013E3182515055  0.671
2012 Marklund N. Pharmacological neuroprotection in severe traumatic brain injury Management of Severe Traumatic Brain Injury: Evidence, Tricks and Pitfalls. 273-279. DOI: 10.1007/978-3-642-28126-6_50  0.514
2011 Wallenquist U, Holmqvist K, Hånell A, Marklund N, Hillered L, Forsberg-Nilsson K. Ibuprofen attenuates the inflammatory response and allows formation of migratory neuroblasts from grafted stem cells after traumatic brain injury. Restorative Neurology and Neuroscience. PMID 24398716 DOI: 10.3233/RNN-2011-606  0.642
2011 Clausen F, HÃ¥nell A, Israelsson C, Hedin J, Ebendal T, Mir AK, Gram H, Marklund N. Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice. The European Journal of Neuroscience. 34: 110-23. PMID 21623956 DOI: 10.1111/J.1460-9568.2011.07723.X  0.479
2011 Marklund N, Hillered L. Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here? British Journal of Pharmacology. 164: 1207-29. PMID 21175576 DOI: 10.1111/J.1476-5381.2010.01163.X  0.665
2011 Tsitsopoulos PP, Tobieson L, Enblad P, Marklund N. Clinical outcome following surgical treatment for bilateral cerebellar infarction. Acta Neurologica Scandinavica. 123: 345-51. PMID 20636449 DOI: 10.1111/J.1600-0404.2010.01404.X  0.327
2010 HÃ¥nell A, Clausen F, Björk M, Jansson K, Philipson O, Nilsson LN, Hillered L, Weinreb PH, Lee D, McIntosh TK, Gimbel DA, Strittmatter SM, Marklund N. Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. Journal of Neurotrauma. 27: 1297-309. PMID 20486800 DOI: 10.1089/Neu.2009.1255  0.777
2009 Skoglund K, Enblad P, Marklund N. Effects of the neurological wake-up test on intracranial pressure and cerebral perfusion pressure in brain-injured patients. Neurocritical Care. 11: 135-42. PMID 19644774 DOI: 10.1007/S12028-009-9255-3  0.439
2009 Clausen F, HÃ¥nell A, Björk M, Hillered L, Mir AK, Gram H, Marklund N. Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice. The European Journal of Neuroscience. 30: 385-96. PMID 19614750 DOI: 10.1111/J.1460-9568.2009.06820.X  0.687
2009 Marklund N, Morales D, Clausen F, HÃ¥nell A, Kiwanuka O, Pitkänen A, Gimbel DA, Philipson O, Lannfelt L, Hillered L, Strittmatter SM, McIntosh TK. Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience. 163: 540-51. PMID 19555742 DOI: 10.1016/J.Neuroscience.2009.06.042  0.73
2009 Marklund N, Sihver S, Hovda DA, LÃ¥ngström B, Watanabe Y, Ronquist G, Bergström M, Hillered L. Increased cerebral uptake of [18F]fluoro-deoxyglucose but not [1-14C]glucose early following traumatic brain injury in rats. Journal of Neurotrauma. 26: 1281-93. PMID 19355837 DOI: 10.1089/Neu.2008.0827  0.671
2009 Marklund N, Blennow K, Zetterberg H, Ronne-Engström E, Enblad P, Hillered L. Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury. Journal of Neurosurgery. 110: 1227-37. PMID 19216653 DOI: 10.3171/2008.9.Jns08584  0.687
2008 Clausen F, Marklund N, Lewén A, Hillered L. The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat. Journal of Neurotrauma. 25: 1449-57. PMID 19118455 DOI: 10.1089/Neu.2008.0585  0.739
2008 Conte V, Raghupathi R, Watson DJ, Fujimoto S, Royo NC, Marklund N, Stocchetti N, McIntosh TK. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restorative Neurology and Neuroscience. 26: 45-56. PMID 18431005  0.732
2007 Marklund N, Bareyre FM, Royo NC, Thompson HJ, Mir AK, Grady MS, Schwab ME, McIntosh TK. Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression. Journal of Neurosurgery. 107: 844-53. PMID 17937233 DOI: 10.3171/Jns-07/10/0844  0.742
2007 Marklund N, Enblad P, Ronne-Engström E. Neurointensive care management of raised intracranial pressure caused by severe valproic acid intoxication. Neurocritical Care. 7: 160-4. PMID 17522786 DOI: 10.1007/S12028-007-0060-6  0.323
2007 Samuelsson C, Hillered L, Zetterling M, Enblad P, Hesselager G, Ryttlefors M, Kumlien E, Lewén A, Marklund N, Nilsson P, Salci K, Ronne-Engström E. Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1309-17. PMID 17228333 DOI: 10.1038/Sj.Jcbfm.9600433  0.556
2006 Thompson HJ, Marklund N, LeBold DG, Morales DM, Keck CA, Vinson M, Royo NC, Grundy R, McIntosh TK. Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody. The European Journal of Neuroscience. 24: 3063-72. PMID 17156367 DOI: 10.1111/J.1460-9568.2006.05197.X  0.769
2006 Marklund N, Salci K, Ronquist G, Hillered L. Energy metabolic changes in the early post-injury period following traumatic brain injury in rats. Neurochemical Research. 31: 1085-93. PMID 16909313 DOI: 10.1007/S11064-006-9120-0  0.719
2006 Marklund N, Bakshi A, Castelbuono DJ, Conte V, McIntosh TK. Evaluation of pharmacological treatment strategies in traumatic brain injury. Current Pharmaceutical Design. 12: 1645-80. PMID 16729876 DOI: 10.2174/138161206776843340  0.667
2006 Thompson HJ, LeBold DG, Marklund N, Morales DM, Hagner AP, McIntosh TK. Cognitive evaluation of traumatically brain-injured rats using serial testing in the Morris water maze. Restorative Neurology and Neuroscience. 24: 109-14. PMID 16720946  0.727
2006 Kunz T, Marklund N, Hillered L, Oliw EH. Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat. Restorative Neurology and Neuroscience. 24: 55-63. PMID 16518028  0.65
2006 Dubreuil CI, Marklund N, Deschamps K, McIntosh TK, McKerracher L. Activation of Rho after traumatic brain injury and seizure in rats. Experimental Neurology. 198: 361-9. PMID 16448651 DOI: 10.1016/J.Expneurol.2005.12.002  0.7
2006 Marklund N, Fulp CT, Shimizu S, Puri R, McMillan A, Strittmatter SM, McIntosh TK. Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Experimental Neurology. 197: 70-83. PMID 16321384 DOI: 10.1016/J.Expneurol.2005.08.029  0.698
2005 Kunz T, Marklund N, Hillered L, Oliw EH. Assessment of the effects of the cyclooxygenase-2 inhibitor rofecoxib on visuospatial learning and hippocampal cell death following kainate-induced seizures in the rat. Brain Research. Cognitive Brain Research. 25: 826-32. PMID 16263251 DOI: 10.1016/J.Cogbrainres.2005.09.017  0.561
2005 Morales DM, Marklund N, Lebold D, Thompson HJ, Pitkanen A, Maxwell WL, Longhi L, Laurer H, Maegele M, Neugebauer E, Graham DI, Stocchetti N, McIntosh TK. Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience. 136: 971-89. PMID 16242846 DOI: 10.1016/J.Neuroscience.2005.08.030  0.769
2005 Clausen F, Lewén A, Marklund N, Olsson Y, McArthur DL, Hillered L. Correlation of hippocampal morphological changes and morris water maze performance after cortical contusion injury in rats. Neurosurgery. 57: 154-63; discussion 1. PMID 15987551 DOI: 10.1227/01.Neu.0000163412.07546.57  0.585
2005 Lenzlinger PM, Shimizu S, Marklund N, Thompson HJ, Schwab ME, Saatman KE, Hoover RC, Bareyre FM, Motta M, Luginbuhl A, Pape R, Clouse AK, Morganti-Kossmann C, McIntosh TK. Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats. Neuroscience. 134: 1047-56. PMID 15979242 DOI: 10.1016/J.Neuroscience.2005.04.048  0.817
2005 Marklund N, Keck C, Hoover R, Soltesz K, Millard M, LeBold D, Spangler Z, Banning A, Benson J, McIntosh TK. Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat. Restorative Neurology and Neuroscience. 23: 31-42. PMID 15846030  0.677
2005 Thompson HJ, Lifshitz J, Marklund N, Grady MS, Graham DI, Hovda DA, McIntosh TK. Lateral fluid percussion brain injury: a 15-year review and evaluation. Journal of Neurotrauma. 22: 42-75. PMID 15665602 DOI: 10.1089/Neu.2005.22.42  0.796
2005 Pitkänen A, Longhi L, Marklund N, Morales DM, McIntosh TK. Neurodegeneration and neuroprotective strategies after traumatic brain injury Drug Discovery Today: Disease Mechanisms. 2: 409-418. DOI: 10.1016/J.Ddmec.2005.11.011  0.656
2003 Royo NC, Schouten JW, Fulp CT, Shimizu S, Marklund N, Graham DI, McIntosh TK. From cell death to neuronal regeneration: building a new brain after traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 801-11. PMID 14503636 DOI: 10.1093/Jnen/62.8.801  0.647
2002 Kunz T, Marklund N, Hillered L, Oliw EH. Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat. Journal of Neurotrauma. 19: 1051-64. PMID 12482118 DOI: 10.1089/089771502760341965  0.684
2002 Cesarini KG, Enblad P, Ronne-Engström E, Marklund N, Salci K, Nilsson P, HÃ¥rdemark HG, Hillered L, Persson L. Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome. Acta Neurochirurgica. 144: 1121-31. PMID 12434168 DOI: 10.1007/S00701-002-1011-9  0.591
2002 Marklund N, Sihver S, LÃ¥ngström B, Bergström M, Hillered L. Effect of traumatic brain injury and nitrone radical scavengers on relative changes in regional cerebral blood flow and glucose uptake in rats. Journal of Neurotrauma. 19: 1139-53. PMID 12427324 DOI: 10.1089/08977150260337958  0.646
2001 Marklund N, Clausen F, Lewander T, Hillered L. Monitoring of reactive oxygen species production after traumatic brain injury in rats with microdialysis and the 4-hydroxybenzoic acid trapping method. Journal of Neurotrauma. 18: 1217-27. PMID 11721740 DOI: 10.1089/089771501317095250  0.703
2001 Marklund N, Lewander T, Clausen F, Hillered L. Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1259-67. PMID 11702041 DOI: 10.1097/00004647-200111000-00002  0.725
2001 Marklund N, Clausen F, McIntosh TK, Hillered L. Free radical scavenger posttreatment improves functional and morphological outcome after fluid percussion injury in the rat. Journal of Neurotrauma. 18: 821-32. PMID 11526988 DOI: 10.1089/089771501316919184  0.766
2001 Sihver S, Marklund N, Hillered L, LÃ¥ngström B, Watanabe Y, Bergström M. Changes in mACh, NMDA and GABA(A) receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections. Journal of Neurochemistry. 78: 417-23. PMID 11483644 DOI: 10.1046/J.1471-4159.2001.00428.X  0.626
2001 Marklund N, Clausen F, Lewén A, Hovda DA, Olsson Y, Hillered L. alpha-Phenyl-tert-N-butyl nitrone (PBN) improves functional and morphological outcome after cortical contusion injury in the rat. Acta Neurochirurgica. 143: 73-81. PMID 11345721 DOI: 10.1007/S007010170141  0.73
2001 Lewén A, Skoglösa Y, Clausen F, Marklund N, Chan PH, Lindholm D, Hillered L. Paradoxical increase in neuronal DNA fragmentation after neuroprotective free radical scavenger treatment in experimental traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 344-50. PMID 11323520 DOI: 10.1097/00004647-200104000-00003  0.689
2001 Ronne-Engström E, Cesarini KG, Enblad P, Hesselager G, Marklund N, Nilsson P, Salci K, Persson L, Hillered L. Intracerebral microdialysis in neurointensive care: the use of urea as an endogenous reference compound. Journal of Neurosurgery. 94: 397-402. PMID 11235942 DOI: 10.3171/Jns.2001.94.3.0397  0.648
2000 Marklund N, Ostman B, Nalmo L, Persson L, Hillered L. Hypoxanthine, uric acid and allantoin as indicators of in vivo free radical reactions. Description of a HPLC method and human brain microdialysis data. Acta Neurochirurgica. 142: 1135-41; discussion . PMID 11129536 DOI: 10.1007/S007010070042  0.561
1997 Marklund N, Salci K, Lewén A, Hillered L. Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain. Neuroreport. 8: 1457-61. PMID 9172153 DOI: 10.1097/00001756-199704140-00026  0.717
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