| Year |
Citation |
Score |
| 2020 |
May MR, Bettridge JT, Desiderio S. Binding and allosteric transmission of histone H3 Lys-4 trimethylation to the recombinase RAG-1 are separable functions of the RAG-2 plant homeodomain finger. The Journal of Biological Chemistry. 295: 9052-9060. PMID 32414844 DOI: 10.1074/Jbc.Ra120.014382 |
0.38 |
|
| 2019 |
Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell DR, Lee S, Zhang H, Michels A, Desiderio S, Sadegh-Nasseri S, Rabb H, Gritsch S, Suva ML, Cahan P, et al. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Cell. 177: 1583-1599.e16. PMID 31150624 DOI: 10.1016/J.Cell.2019.05.007 |
0.644 |
|
| 2018 |
Wagner CL, Hanumanthu VS, Talbot CC, Abraham RS, Hamm D, Gable DL, Kanakry CG, Applegate CD, Siliciano J, Jackson JB, Desiderio SV, Alder JK, Luznik L, Armanios M. Short telomere syndromes cause a primary T cell immunodeficiency. The Journal of Clinical Investigation. PMID 30179220 DOI: 10.1172/Jci120216 |
0.352 |
|
| 2018 |
Ward A, Kumari G, Sen R, Desiderio S. The RAG-2 Inhibitory Domain Gates Accessibility Of The V(D)J Recombinase To Chromatin. Molecular and Cellular Biology. PMID 29760281 DOI: 10.1128/Mcb.00159-18 |
0.372 |
|
| 2018 |
May M, Desiderio S, Bettridge JT. An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase Blood. 132: 512-512. DOI: 10.1182/Blood-2018-99-116675 |
0.443 |
|
| 2017 |
Lu W, Dordai D, Huso D, Desiderio S. Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis. Blood. PMID 29167177 DOI: 10.1182/Blood-2017-06-793539 |
0.39 |
|
| 2017 |
Bettridge J, Na CH, Pandey A, Desiderio S. H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28174273 DOI: 10.1073/Pnas.1615727114 |
0.37 |
|
| 2016 |
Desiderio S. Pumping the breaks on B cell development. The Journal of Experimental Medicine. 213: 140. PMID 26858362 DOI: 10.1084/Jem.2132Insight1 |
0.384 |
|
| 2016 |
Bettridge JT, Na C, Pandey A, Desiderio S. Allosteric Regulation of V(D)J Recombination By Active Chromatin Blood. 128: 3707-3707. DOI: 10.1182/Blood.V128.22.3707.3707 |
0.41 |
|
| 2015 |
Lu C, Ward A, Bettridge J, Liu Y, Desiderio S. An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation. Cell Reports. 10: 29-38. PMID 25543141 DOI: 10.1016/J.Celrep.2014.12.001 |
0.441 |
|
| 2013 |
Halper-Stromberg E, Steranka J, Giraldo-Castillo N, Fuller T, Desiderio S, Burns KH. Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies Bmc Genomics. 14. PMID 23957733 DOI: 10.1186/1471-2164-14-565 |
0.403 |
|
| 2013 |
Rybanska-Spaeder I, Reynolds TL, Chou J, Prakash M, Jefferson T, Huso DL, Desiderio S, Franco S. 53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation. Molecular Cancer Research : McR. 11: 1223-34. PMID 23858098 DOI: 10.1158/1541-7786.Mcr-13-0252-T |
0.37 |
|
| 2013 |
Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Desiderio S, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/Msb.2013.12 |
0.348 |
|
| 2013 |
Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS. The transcriptional repressor NKAP is required for the development of iNKT cells. Nature Communications. 4: 1582. PMID 23481390 DOI: 10.1038/Ncomms2580 |
0.37 |
|
| 2012 |
Cooper CL, Hardy RR, Reth M, Desiderio S. Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors. Blood. 119: 5438-48. PMID 22517907 DOI: 10.1182/Blood-2011-12-397976 |
0.455 |
|
| 2011 |
Zhang L, Reynolds TL, Shan X, Desiderio S. Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. Immunity. 34: 163-74. PMID 21349429 DOI: 10.1016/J.Immuni.2011.02.003 |
0.457 |
|
| 2011 |
Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D. Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice. Blood. 117: 3131-9. PMID 21228325 DOI: 10.1182/Blood-2010-05-286070 |
0.433 |
|
| 2010 |
Desiderio S. Temporal and spatial regulatory functions of the V(D)J recombinase Seminars in Immunology. 22: 362-369. PMID 21036059 DOI: 10.1016/J.Smim.2010.09.001 |
0.424 |
|
| 2009 |
Liu Y, Zhang L, Desiderio S. Temporal and spatial regulation of V(D)J recombination: Interactions of extrinsic factors with the RAG complex Advances in Experimental Medicine and Biology. 650: 157-165. PMID 19731809 DOI: 10.1007/978-1-4419-0296-2_13 |
0.462 |
|
| 2009 |
Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M. Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity. The Journal of Biological Chemistry. 284: 19437-44. PMID 19473983 DOI: 10.1074/Jbc.M109.006098 |
0.318 |
|
| 2009 |
Li L, Zhang L, Fan J, Greenberg KE, Desiderio S, Rassool FV, Small D. B-Lymphocyte Development Is Impaired by FLT3/ITD Signaling in Knock-in Mice Because of Defective Non-Homologous End-Joining. Blood. 114: 184-184. DOI: 10.1182/Blood.V114.22.184.184 |
0.444 |
|
| 2007 |
Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S. A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity. 27: 561-71. PMID 17936034 DOI: 10.1016/J.Immuni.2007.09.005 |
0.447 |
|
| 2007 |
Youn MY, Yoo HS, Kim MJ, Hwang SY, Choi Y, Desiderio SV, Yoo JY. hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions. The Journal of Biological Chemistry. 282: 34727-34. PMID 17911113 DOI: 10.1074/Jbc.M705411200 |
0.339 |
|
| 2006 |
Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S. Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science (New York, N.Y.). 314: 122-5. PMID 17023658 DOI: 10.1126/Science.1127815 |
0.305 |
|
| 2005 |
Jiang H, Chang FC, Ross AE, Lee J, Nakayama K, Desiderio S. Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle Molecular Cell. 18: 699-709. PMID 15949444 DOI: 10.1016/J.Molcel.2005.05.011 |
0.417 |
|
| 2005 |
Jackson TA, Taylor HE, Sharma D, Desiderio S, Danoff SK. Vascular endothelial growth factor receptor-2: counter-regulation by the transcription factors, TFII-I and TFII-IRD1. The Journal of Biological Chemistry. 280: 29856-63. PMID 15941713 DOI: 10.1074/Jbc.M500335200 |
0.318 |
|
| 2004 |
Danoff SK, Taylor HE, Blackshaw S, Desiderio S. TFII-I, a candidate gene for Williams syndrome cognitive profile: parallels between regional expression in mouse brain and human phenotype. Neuroscience. 123: 931-8. PMID 14751286 DOI: 10.1016/J.Neuroscience.2003.08.038 |
0.311 |
|
| 2004 |
Jiang H, Ross AE, Desiderio S. Cycle-dependent Accumulation in Vivo of Transposition-competent Complexes between Recombination Signal Ends and Full-length RAG Proiteins Journal of Biological Chemistry. 279: 8478-8486. PMID 14660558 DOI: 10.1074/Jbc.M311219200 |
0.453 |
|
| 2003 |
Tretter T, Ross AE, Dordai DI, Desiderio S. Mimicry of Pre-B Cell Receptor Signaling by Activation of the Tyrosine Kinase Blk Journal of Experimental Medicine. 198: 1863-1873. PMID 14662906 DOI: 10.1084/Jem.20030729 |
0.485 |
|
| 2003 |
Ross AE, Vuica M, Desiderio S. Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells Molecular and Cellular Biology. 23: 5308-5319. PMID 12861017 DOI: 10.1128/Mcb.23.15.5308-5319.2003 |
0.399 |
|
| 2003 |
Desiderio S, Yoo JY. A genome-wide analysis of the acute-phase response and its regulation by Stat3β Annals of the New York Academy of Sciences. 987: 280-284. PMID 12727653 DOI: 10.1111/J.1749-6632.2003.Tb06062.X |
0.314 |
|
| 2002 |
Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. cGMP-dependent protein kinase Iβ physically and functionally interacts with the transcriptional regulator TFII-I Journal of Biological Chemistry. 277: 32003-32014. PMID 12082086 DOI: 10.1074/Jbc.M112332200 |
0.393 |
|
| 2001 |
Egloff AM, Desiderio S. Identification of Phosphorylation Sites for Bruton's Tyrosine Kinase within the Transcriptional Regulator BAP/TFII-I Journal of Biological Chemistry. 276: 27806-27815. PMID 11373296 DOI: 10.1074/Jbc.M103692200 |
0.464 |
|
| 2001 |
Li W, Chang FC, Desiderio S. RAG-1 mutations associated with B-Cell-negative SCID dissociate the nicking and transesterification steps of V(D)J recombination Molecular and Cellular Biology. 21: 3935-3946. PMID 11359901 DOI: 10.1128/Mcb.21.12.3935-3946.2001 |
0.393 |
|
| 2001 |
Yoo JY, Wang W, Desiderio S, Nathans D. Synergistic activity of STAT3 and c-Jun at a specific array of DNA elements in the alpha 2-macroglobulin promoter. The Journal of Biological Chemistry. 276: 26421-9. PMID 11319221 DOI: 10.1074/Jbc.M009935200 |
0.329 |
|
| 2000 |
Texido G, Su IH, Mecklenbräuker I, Saijo K, Malek SN, Desiderio S, Rajewsky K, Tarakhovsky A. The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation. Molecular and Cellular Biology. 20: 1227-33. PMID 10648608 DOI: 10.1128/Mcb.20.4.1227-1233.2000 |
0.485 |
|
| 1999 |
Lee J, Desiderio S. Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair Immunity. 11: 771-781. PMID 10626899 DOI: 10.1016/S1074-7613(00)80151-X |
0.374 |
|
| 1999 |
Swanson PC, Desiderio S. RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex Molecular and Cellular Biology. 19: 3674-3683. PMID 10207091 DOI: 10.1128/Mcb.19.5.3674 |
0.403 |
|
| 1998 |
Swanson PC, Desiderio S. V(D)J recombination signal recognition: Distinct, overlapping DNA- protein contacts in complexes containing RAG1 with and without RAG2 Immunity. 9: 115-125. PMID 9697841 DOI: 10.1016/S1074-7613(00)80593-2 |
0.334 |
|
| 1998 |
Malek SN, Dordai DI, Reim J, Dintzis H, Desiderio S. Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase Proceedings of the National Academy of Sciences of the United States of America. 95: 7351-7356. PMID 9636152 DOI: 10.1073/Pnas.95.13.7351 |
0.463 |
|
| 1997 |
Li W, Swanson P, Desiderio S. RAG-1- and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution Molecular and Cellular Biology. 17: 6932-6939. PMID 9372925 DOI: 10.1128/Mcb.17.12.6932 |
0.35 |
|
| 1997 |
Desiderio S. Role of Btk in B cell development and signaling Current Opinion in Immunology. 9: 534-540. PMID 9287186 DOI: 10.1016/S0952-7915(97)80107-0 |
0.435 |
|
| 1997 |
Vuica M, Desiderio S, Schneck JP. Differential effects of B cell receptor and B cell receptor-FcγRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62 Journal of Experimental Medicine. 186: 259-267. PMID 9221755 DOI: 10.1084/Jem.186.2.259 |
0.422 |
|
| 1997 |
Zwollo P, Arrieta H, Ede K, Molinder K, Desiderio S, Pollock R. The Pax-5 gene is alternatively spliced during B-cell development Journal of Biological Chemistry. 272: 10160-10168. PMID 9092562 DOI: 10.1074/Jbc.272.15.10160 |
0.476 |
|
| 1997 |
Yang W, Desiderio S. Bap-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement Proceedings of the National Academy of Sciences of the United States of America. 94: 604-609. PMID 9012831 DOI: 10.1073/Pnas.94.2.604 |
0.46 |
|
| 1996 |
Li Z, Dordai DI, Lee J, Desiderio S. A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle Immunity. 5: 575-589. PMID 8986717 DOI: 10.1016/S1074-7613(00)80272-1 |
0.438 |
|
| 1996 |
Desiderio S, Lin WC, Li Z. The cell cycle and V(D)J recombination Current Topics in Microbiology and Immunology. 217: 45-59. PMID 8787617 DOI: 10.1007/978-3-642-50140-1_4 |
0.379 |
|
| 1996 |
Malek SN, Yang CH, Earnshaw WC, Kozak CA, Desiderio S. p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains. The Journal of Biological Chemistry. 271: 6952-62. PMID 8636124 DOI: 10.1074/Jbc.271.12.6952 |
0.436 |
|
| 1995 |
Lin WC, Desiderio S. V(D)J recombination and the cell cycle Immunology Today. 16: 279-289. PMID 7662097 DOI: 10.1016/0167-5699(95)80182-0 |
0.405 |
|
| 1995 |
Yang W, Malek SN, Desiderio S. An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo Journal of Biological Chemistry. 270: 20832-20840. PMID 7657668 DOI: 10.1074/Jbc.270.35.20832 |
0.385 |
|
| 1995 |
Desiderio S. Lymphopoiesis: Transcription factors controlling B-cell development Current Biology. 5: 605-608. PMID 7552167 DOI: 10.1016/S0960-9822(95)00121-7 |
0.396 |
|
| 1994 |
Zwollo P, Desiderio S. Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein Journal of Biological Chemistry. 269: 15310-15317. PMID 8195169 |
0.418 |
|
| 1994 |
Lin WC, Desiderio S. Cell cycle regulation of V(D)J recombination-activating protein RAG-2 Proceedings of the National Academy of Sciences of the United States of America. 91: 2733-2737. PMID 8146183 DOI: 10.1073/Pnas.91.7.2733 |
0.452 |
|
| 1994 |
Desiderio S. The B cell antigen receptor in B-cell development Current Opinion in Immunology. 6: 248-256. PMID 8011209 DOI: 10.1016/0952-7915(94)90098-1 |
0.45 |
|
| 1994 |
Desiderio S, Siliciano JD. The Itk/Btk/Tec family of protein-tyrosine kinases Chemical Immunology. 59: 191-210. PMID 7945928 DOI: 10.1159/000319255 |
0.312 |
|
| 1994 |
Janis EM, Siliciano JD, Isaac DD, Griffin CA, Hawkins AL, Kozak CA, Desiderio S. Mapping of the gene for the tyrosine kinase Itk to a region of conserved synteny between mouse chromosome 11 and human chromosome 5q. Genomics. 23: 269-71. PMID 7829087 DOI: 10.1006/Geno.1994.1492 |
0.378 |
|
| 1993 |
Lin WC, Desiderio S. Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation Science. 260: 953-959. PMID 8493533 DOI: 10.1126/Science.8493533 |
0.43 |
|
| 1993 |
Klages S, Adam D, Eiseman E, Fargnoli J, Dymecki SM, Desiderio SV, Bolen JB. Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase. Oncogene. 8: 713-9. PMID 8437854 |
0.61 |
|
| 1993 |
Oltz EM, Alt FW, Lin WC, Chen J, Taccioli G, Desiderio S, Rathbun G. A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination. Molecular and Cellular Biology. 13: 6223-30. PMID 8413222 DOI: 10.1128/Mcb.13.10.6223 |
0.503 |
|
| 1992 |
Dymecki SM, Zwollo P, Zeller K, Kuhajda FP, Desiderio SV. Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk. The Journal of Biological Chemistry. 267: 4815-23. PMID 1537861 |
0.681 |
|
| 1992 |
Desiderio SV. B-cell activation. Current Opinion in Immunology. 4: 252-6. PMID 1418702 DOI: 10.1016/0952-7915(92)90073-N |
0.459 |
|
| 1992 |
Siliciano JD, Morrow TA, Desiderio SV. itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. Proceedings of the National Academy of Sciences of the United States of America. 89: 11194-8. PMID 1280821 DOI: 10.1073/Pnas.89.23.11194 |
0.428 |
|
| 1991 |
Kozak CA, Dymecki SM, Niederhuber JE, Desiderio SV. Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14. Genomics. 9: 762-4. PMID 2037301 DOI: 10.1016/0888-7543(91)90372-L |
0.644 |
|
| 1991 |
Wilson RB, Kiledjian M, Shen CP, Benezra R, Zwollo P, Dymecki SM, Desiderio SV, Kadesch T. Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development. Molecular and Cellular Biology. 11: 6185-91. PMID 1944284 DOI: 10.1128/Mcb.11.12.6185 |
0.662 |
|
| 1991 |
Alessandrini A, Desiderio SV. Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation. Molecular and Cellular Biology. 11: 2096-107. PMID 1900920 DOI: 10.1128/Mcb.11.4.2096 |
0.426 |
|
| 1990 |
Dymecki SM, Niederhuber JE, Desiderio SV. Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells. Science (New York, N.Y.). 247: 332-6. PMID 2404338 DOI: 10.1126/Science.2404338 |
0.688 |
|
| 1988 |
Desiderio SV, Wolff KR. Rearrangement of exogenous immunoglobulin VH and DJH gene segments after retroviral transduction into immature lymphoid cell lines. The Journal of Experimental Medicine. 167: 372-88. PMID 2831291 |
0.364 |
|
| 1987 |
Alessandrini A, Pierce JH, Baltimore D, Desiderio SV. Continuing rearrangement of immunoglobulin and T-cell receptor genes in a Ha-ras-transformed lymphoid progenitor cell line. Proceedings of the National Academy of Sciences of the United States of America. 84: 1799-803. PMID 3470759 DOI: 10.1073/Pnas.84.7.1799 |
0.563 |
|
| 1987 |
Halligan BD, Desiderio SV. Identification of a DNA binding protein that recognizes the nonamer recombinational signal sequence of immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 84: 7019-23. PMID 3118358 DOI: 10.1073/Pnas.84.20.7019 |
0.431 |
|
| 1984 |
Desiderio S, Baltimore D. Double-stranded cleavage by cell extracts near recombinational signal sequences of immunoglobulin genes Nature. 308: 860-862. PMID 6325923 DOI: 10.1038/308860a0 |
0.502 |
|
| 1984 |
Desiderio SV, Yancopoulos GD, Paskind M, Thomas E, Boss MA, Landau N, Alt FW, Baltimore D. Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells. Nature. 311: 752-5. PMID 6092963 DOI: 10.1038/311752A0 |
0.597 |
|
| 1984 |
Yancopoulos GD, Desiderio SV, Paskind M, Kearney JF, Baltimore D, Alt FW. Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines. Nature. 311: 727-33. PMID 6092962 DOI: 10.1038/311727A0 |
0.599 |
|
| 1981 |
Desiderio SV, Kelly TJ. Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein. Journal of Molecular Biology. 145: 319-37. PMID 7265205 DOI: 10.1016/0022-2836(81)90208-4 |
0.32 |
|
| 1980 |
Challberg MD, Desiderio SV, Kelly TJ. Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands. Proceedings of the National Academy of Sciences of the United States of America. 77: 5105-9. PMID 6933548 DOI: 10.1073/Pnas.77.9.5105 |
0.327 |
|
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